BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50529300 CN(C)C(=O)c1ccc2n(nc(Oc3c(Cl)cccc3C(F)(F)F)c2c1)-c1ccc(cc1)C(O)=O InChI=1S/C24H17ClF3N3O4/c1-30(2)22(32)14-8-11-19-16(12-14)21(29-31(19)15-9-6-13(7-10-15)23(33)34)35-20-17(24(26,27)28)4-3-5-18(20)25/h3-12H,1-2H3,(H,33,34) PRFOAGMHUSKCKE-UHFFFAOYSA-N 50203462 CHEMBL3931161 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2016.10.023 10.7270/Q2D79DDH 27815118 Ouvry, G; Bouix-Peter, C; Ciesielski, F; Chantalat, L; Christin, O; Comino, C; Duvert, D; Feret, C; Harris, CS; Lamy, L; Luzy, AP; Musicki, B; Orfila, D; Pascau, J; Parnet, V; Perrin, A; Pierre, R; Polge, G; Raffin, C; Rival, Y; Taquet, N; Thoreau, E; Hennequin, LF Galderma R & D http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203462&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 79U 5LWP 122235238 375980075 CHEMBL3931161 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36568 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 27 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36569 COc1cccc(C2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H16ClF3N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-14(25)11-17(19)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3 LORGBPUOJISMFM-UHFFFAOYSA-N 20131 5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 2 (racemate) Oxysterols receptor LXR-beta 300 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20131&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23643871 46520118 ZINC14972814 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36570 COc1cccc([C@H]2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H16ClF3N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-14(25)11-17(19)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3/t23-/m1/s1 LORGBPUOJISMFM-HSZRJFAPSA-N 20132 (2R)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 3-R Oxysterols receptor LXR-beta 67 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20132&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648532 46520119 ZINC14972814 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36571 COc1cccc(C2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(F)cc2)c1OC InChI=1S/C23H16F4N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-14(25)11-17(19)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3 QFPFADQBVCQGIH-UHFFFAOYSA-N 20133 2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 5 Oxysterols receptor LXR-beta 76 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20133&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648533 46520120 ZINC14972822 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36572 COc1cccc(C2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(C)cc2)c1OC InChI=1S/C24H19F3N2O3S/c1-13-7-9-14(10-8-13)22-28-29(23(30)20-17(26)11-15(25)12-18(20)27)24(33-22)16-5-4-6-19(31-2)21(16)32-3/h4-12,24H,1-3H3 JBJCOXFQDYYDCT-UHFFFAOYSA-N 20134 2-(2,3-dimethoxyphenyl)-5-(4-methylphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 6 Oxysterols receptor LXR-beta 200 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20134&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648534 46520121 ZINC14972831 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36573 COc1cccc(C2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(Cl)c(Cl)c2)c1OC InChI=1S/C23H15Cl2F3N2O3S/c1-32-18-5-3-4-13(20(18)33-2)23-30(22(31)19-16(27)9-12(26)10-17(19)28)29-21(34-23)11-6-7-14(24)15(25)8-11/h3-10,23H,1-2H3 ISPXLKSACDLINS-UHFFFAOYSA-N 20147 5-(3,4-dichlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 7 Oxysterols receptor LXR-beta >10000 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20147&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648547 46520134 ZINC14972933 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36574 COc1ccccc1C1SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(Cl)cc1 InChI=1S/C22H14ClF3N2O2S/c1-30-18-5-3-2-4-15(18)22-28(21(29)19-16(25)10-14(24)11-17(19)26)27-20(31-22)12-6-8-13(23)9-7-12/h2-11,22H,1H3 OAGHMLOTIYBLDR-UHFFFAOYSA-N 20135 5-(4-chlorophenyl)-2-(2-methoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 8 Oxysterols receptor LXR-beta 35 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20135&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648535 46520122 ZINC14972839 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36575 COc1cccc(c1)C1SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(Cl)cc1 InChI=1S/C22H14ClF3N2O2S/c1-30-16-4-2-3-13(9-16)22-28(21(29)19-17(25)10-15(24)11-18(19)26)27-20(31-22)12-5-7-14(23)8-6-12/h2-11,22H,1H3 IJPQKGYDDLFFKO-UHFFFAOYSA-N 20148 5-(4-chlorophenyl)-2-(3-methoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 9 Oxysterols receptor LXR-beta 3700 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20148&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648548 46520135 ZINC14972941 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36576 COc1cc(F)ccc1C1SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(F)cc1 InChI=1S/C22H13F5N2O2S/c1-31-18-10-13(24)6-7-15(18)22-29(21(30)19-16(26)8-14(25)9-17(19)27)28-20(32-22)11-2-4-12(23)5-3-11/h2-10,22H,1H3 SANUVDQUZBJEFO-UHFFFAOYSA-N 20136 2-(4-fluoro-2-methoxyphenyl)-5-(4-fluorophenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 10 Oxysterols receptor LXR-beta 6 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20136&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648536 46520123 ZINC14972847 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36577 Fc1cc(F)c(C(=O)N2N=C(SC2c2ccccc2OC(F)(F)F)c2ccc(Cl)cc2)c(F)c1 InChI=1S/C22H11ClF6N2O2S/c23-12-7-5-11(6-8-12)19-30-31(20(32)18-15(25)9-13(24)10-16(18)26)21(34-19)14-3-1-2-4-17(14)33-22(27,28)29/h1-10,21H ODTFPULHXAAGNG-UHFFFAOYSA-N 20149 5-(4-chlorophenyl)-2-[2-(trifluoromethoxy)phenyl]-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 11 Oxysterols receptor LXR-beta 3400 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20149&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648549 46520136 ZINC14972949 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36578 FC(F)Oc1ccccc1C1SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(F)cc1 InChI=1S/C22H12F6N2O2S/c23-12-7-5-11(6-8-12)19-29-30(20(31)18-15(25)9-13(24)10-16(18)26)21(33-19)14-3-1-2-4-17(14)32-22(27)28/h1-10,21-22H NEYYMHOBVMYCFZ-UHFFFAOYSA-N 20137 2-[2-(difluoromethoxy)phenyl]-5-(4-fluorophenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 12 Oxysterols receptor LXR-beta 150 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20137&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648537 46520124 ZINC14972855 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36579 Fc1cc(F)c(C(=O)N2N=C(SC2c2cccc3OC(F)(F)Oc23)c2ccc(Cl)cc2)c(F)c1 InChI=1S/C22H10ClF5N2O3S/c23-11-6-4-10(5-7-11)19-29-30(20(31)17-14(25)8-12(24)9-15(17)26)21(34-19)13-2-1-3-16-18(13)33-22(27,28)32-16/h1-9,21H IUOGEZKRWWZZDU-UHFFFAOYSA-N 20138 5-(4-chlorophenyl)-2-(2,2-difluoro-2H-1,3-benzodioxol-4-yl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 13 Oxysterols receptor LXR-beta 800 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20138&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648538 46520125 ZINC14972863 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36580 COc1ncccc1C1SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(F)cc1 InChI=1S/C21H13F4N3O2S/c1-30-18-14(3-2-8-26-18)21-28(20(29)17-15(24)9-13(23)10-16(17)25)27-19(31-21)11-4-6-12(22)7-5-11/h2-10,21H,1H3 JBGKBFVOUGZORS-UHFFFAOYSA-N 20139 5-(4-fluorophenyl)-2-(2-methoxypyridin-3-yl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 14 Oxysterols receptor LXR-beta 210 7.2 37.00 C Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20139&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648539 46520126 ZINC14972870 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36581 COc1ccccc1C1(C)SC(=NN1C(=O)c1c(F)cc(F)cc1F)c1ccc(F)cc1 InChI=1S/C23H16F4N2O2S/c1-23(16-5-3-4-6-19(16)31-2)29(22(30)20-17(26)11-15(25)12-18(20)27)28-21(32-23)13-7-9-14(24)10-8-13/h3-12H,1-2H3 QXTOGDQRXCPBNC-UHFFFAOYSA-N 20150 5-(4-fluorophenyl)-2-(2-methoxyphenyl)-2-methyl-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 15 Oxysterols receptor LXR-beta 4000 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20150&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648550 46520137 ZINC14972957 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36582 COc1cccc(C2SC(=NN2C(=O)c2ccccc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H18ClFN2O3S/c1-29-19-9-5-7-17(20(19)30-2)23-27(22(28)16-6-3-4-8-18(16)25)26-21(31-23)14-10-12-15(24)13-11-14/h3-13,23H,1-2H3 SSHNBLVLMIFHDU-UHFFFAOYSA-N 20151 5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2-fluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 17 Oxysterols receptor LXR-beta 7700 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20151&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648551 46520138 ZINC14972965 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36583 COc1cccc(C2SC(=NN2C(=O)c2ccc(F)cc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H17ClF2N2O3S/c1-30-19-5-3-4-17(20(19)31-2)23-28(22(29)16-11-10-15(25)12-18(16)26)27-21(32-23)13-6-8-14(24)9-7-13/h3-12,23H,1-2H3 KGAJHUFABOMAGA-UHFFFAOYSA-N 20140 5-(4-chlorophenyl)-3-[(2,4-difluorophenyl)carbonyl]-2-(2,3-dimethoxyphenyl)-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 18 Oxysterols receptor LXR-beta 980 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20140&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648540 46520127 ZINC14972879 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36584 COc1cccc(C2SC(=NN2C(=O)c2c(F)ccc(F)c2F)c2ccc(F)cc2)c1OC InChI=1S/C23H16F4N2O3S/c1-31-17-5-3-4-14(20(17)32-2)23-29(22(30)18-15(25)10-11-16(26)19(18)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3 GWQVYTYBBVOPAI-UHFFFAOYSA-N 20152 2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-3-[(2,3,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 19 Oxysterols receptor LXR-beta 970 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20152&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648552 46520139 ZINC14972973 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36585 COc1cccc(C2SC(=NN2C(=O)c2cc(F)c(F)cc2F)c2ccc(F)cc2)c1OC InChI=1S/C23H16F4N2O3S/c1-31-19-5-3-4-14(20(19)32-2)23-29(22(30)15-10-17(26)18(27)11-16(15)25)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3 ROLKOYRAZLSJBT-UHFFFAOYSA-N 20153 2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-3-[(2,4,5-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 20 Oxysterols receptor LXR-beta 600 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20153&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648553 46520140 ZINC14972980 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36586 COc1cccc(C2SC(=NN2C(=O)c2cccc(F)c2)c2ccc(F)c(F)c2)c1OC InChI=1S/C23H17F3N2O3S/c1-30-19-8-4-7-16(20(19)31-2)23-28(22(29)14-5-3-6-15(24)11-14)27-21(32-23)13-9-10-17(25)18(26)12-13/h3-12,23H,1-2H3 ZMVRODFTWKZWCS-UHFFFAOYSA-N 20141 5-(3,4-difluorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(3-fluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 21 Oxysterols receptor LXR-beta 560 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20141&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648541 46520128 ZINC14972886 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36587 COc1cccc(C2SC(=NN2C(=O)c2cc(F)cc(F)c2)c2ccc(F)cc2)c1OC InChI=1S/C23H17F3N2O3S/c1-30-19-5-3-4-18(20(19)31-2)23-28(22(29)14-10-16(25)12-17(26)11-14)27-21(32-23)13-6-8-15(24)9-7-13/h3-12,23H,1-2H3 VZTOPZAXDXYSBN-UHFFFAOYSA-N 20142 3-[(3,5-difluorophenyl)carbonyl]-2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 22 Oxysterols receptor LXR-beta 470 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20142&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648542 46520129 ZINC14972895 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36588 COc1cccc(C2SC(=NN2C(=O)c2cccc(Cl)c2)c2ccc(F)cc2)c1OC InChI=1S/C23H18ClFN2O3S/c1-29-19-8-4-7-18(20(19)30-2)23-27(22(28)15-5-3-6-16(24)13-15)26-21(31-23)14-9-11-17(25)12-10-14/h3-13,23H,1-2H3 KDDWANWSZBFGNC-UHFFFAOYSA-N 20154 3-[(3-chlorophenyl)carbonyl]-2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 23 Oxysterols receptor LXR-beta 250 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20154&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648554 46520141 ZINC14972988 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36589 COc1cccc(C2SC(=NN2C(=O)c2cc(F)ccc2C)c2ccc(F)cc2)c1OC InChI=1S/C24H20F2N2O3S/c1-14-7-10-17(26)13-19(14)23(29)28-24(18-5-4-6-20(30-2)21(18)31-3)32-22(27-28)15-8-11-16(25)12-9-15/h4-13,24H,1-3H3 VKBIQBUYQXDRMY-UHFFFAOYSA-N 20143 2-(2,3-dimethoxyphenyl)-3-[(5-fluoro-2-methylphenyl)carbonyl]-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 24 Oxysterols receptor LXR-beta 140 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20143&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648543 46520130 ZINC14972903 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36590 COc1cc(F)c(C(=O)N2N=C(SC2c2cccc(OC)c2OC)c2ccc(F)cc2)c(F)c1 InChI=1S/C24H19F3N2O4S/c1-31-15-11-17(26)20(18(27)12-15)23(30)29-24(16-5-4-6-19(32-2)21(16)33-3)34-22(28-29)13-7-9-14(25)10-8-13/h4-12,24H,1-3H3 SPEZOWKRIVQCNP-UHFFFAOYSA-N 20144 3-[(2,6-difluoro-4-methoxyphenyl)carbonyl]-2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 25 Oxysterols receptor LXR-beta 170 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20144&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648544 46520131 ZINC14972911 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36591 COc1cccc(C2SC(=NN2C(=O)c2c(F)cc(Br)cc2F)c2ccc(F)cc2)c1OC InChI=1S/C23H16BrF3N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-13(24)11-17(19)27)28-21(33-23)12-6-8-14(25)9-7-12/h3-11,23H,1-2H3 MOOQLWMHXDNZEH-UHFFFAOYSA-N 20145 3-[(4-bromo-2,6-difluorophenyl)carbonyl]-2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 26 Oxysterols receptor LXR-beta 160 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20145&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648545 46520132 ZINC14972918 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36592 COc1cccc(C2SC(=NN2C(=O)c2cc(F)c(F)c(OC)c2F)c2ccc(F)cc2)c1OC InChI=1S/C24H18F4N2O4S/c1-32-17-6-4-5-14(20(17)33-2)24-30(29-22(35-24)12-7-9-13(25)10-8-12)23(31)15-11-16(26)19(28)21(34-3)18(15)27/h4-11,24H,1-3H3 HBEVEKLDXZVCSW-UHFFFAOYSA-N 20146 2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-3-[(2,4,5-trifluoro-3-methoxyphenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 27 Oxysterols receptor LXR-beta 81 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20146&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648546 46520133 ZINC14972925 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36596 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 23 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797953 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36597 COc1cccc(C2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H16ClF3N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-14(25)11-17(19)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3 LORGBPUOJISMFM-UHFFFAOYSA-N 20131 5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 2 (racemate) Oxysterols receptor LXR-beta 300 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797953 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20131&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23643871 46520118 ZINC14972814 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36598 COc1cccc([C@H]2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H16ClF3N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-14(25)11-17(19)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3/t23-/m1/s1 LORGBPUOJISMFM-HSZRJFAPSA-N 20132 (2R)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 3-R Oxysterols receptor LXR-beta 66 Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797953 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20132&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648532 46520119 ZINC14972814 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36599 COc1cccc([C@@H]2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H16ClF3N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-14(25)11-17(19)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3/t23-/m0/s1 LORGBPUOJISMFM-QHCPKHFHSA-N 20155 (2S)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 4-S Oxysterols receptor LXR-beta Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797953 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20155&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648555 46520142 ZINC14972810 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36602 COc1cccc([C@@H]2SC(=NN2C(=O)c2c(F)cc(F)cc2F)c2ccc(Cl)cc2)c1OC InChI=1S/C23H16ClF3N2O3S/c1-31-18-5-3-4-15(20(18)32-2)23-29(22(30)19-16(26)10-14(25)11-17(19)27)28-21(33-23)12-6-8-13(24)9-7-12/h3-11,23H,1-2H3/t23-/m0/s1 LORGBPUOJISMFM-QHCPKHFHSA-N 20155 (2S)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4,6-trifluorophenyl)carbonyl]-2,3-dihydro-1,3,4-thiadiazole::N-Acylthiadiazoline, 4-S Oxysterols receptor LXR-beta Curated from the literature by BindingDB 10.1021/jm070453f 10.7270/Q2BK19N6 17665897 aid1797952 Molteni, V; Li, X; Nabakka, J; Liang, F; Wityak, J; Koder, A; Vargas, L; Romeo, R; Mitro, N; Mak, PA; Seidel, HM; Haslam, JA; Chow, D; Tuntland, T; Spalding, TA; Brock, A; Bradley, M; Castrillo, A; Tontonoz, P; Saez, E GNF http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20155&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23648555 46520142 ZINC14972810 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 859984 CC(CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F InChI=1S/C34H33ClF3NO3/c1-24(18-19-42-29-16-8-10-25(20-29)21-32(40)41)39(22-28-15-9-17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41) ZLJZDYOBXVOTSA-UHFFFAOYSA-N 426493 US10543183, Compound SB742881::US10669296, Compound SB742881::US10945978, Compound 25 Oxysterols receptor LXR-beta 25.0 US Patent 10.7270/Q2JW8H8C aid1804094 US10543183 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=426493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=426493&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 68861577 434320823 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36614 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 20 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36615 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 30 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36616 COc1ccc(NC2=C(C(=O)N(Cc3ccccc3)C2=O)c2ccccc2)cc1 InChI=1S/C24H20N2O3/c1-29-20-14-12-19(13-15-20)25-22-21(18-10-6-3-7-11-18)23(27)26(24(22)28)16-17-8-4-2-5-9-17/h2-15,25H,16H2,1H3 HLZMYWLMBBLASX-UHFFFAOYSA-N 20156 1-benzyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987::Substituted Maleimide, 4 Oxysterols receptor LXR-beta 40 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20156&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search L05 2ACL 5288679 49688231 DB08063 ZINC13671633 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36617 O=C1N(Cc2ccccc2)C(=O)C(=C1Nc1ccccc1)c1ccccc1 InChI=1S/C23H18N2O2/c26-22-20(18-12-6-2-7-13-18)21(24-19-14-8-3-9-15-19)23(27)25(22)16-17-10-4-1-5-11-17/h1-15,24H,16H2 GLDDBILAEOMQJI-UHFFFAOYSA-N 20157 1-benzyl-3-phenyl-4-(phenylamino)-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 5 Oxysterols receptor LXR-beta 70 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20157&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24768116 49688232 ZINC13671635 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36618 Clc1ccc(NC2=C(C(=O)N(Cc3ccccc3)C2=O)c2ccccc2)cc1 InChI=1S/C23H17ClN2O2/c24-18-11-13-19(14-12-18)25-21-20(17-9-5-2-6-10-17)22(27)26(23(21)28)15-16-7-3-1-4-8-16/h1-14,25H,15H2 XNAXKONPRDDOBL-UHFFFAOYSA-N 20158 1-benzyl-3-[(4-chlorophenyl)amino]-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 6 Oxysterols receptor LXR-beta 110 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20158&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24768117 49688233 ZINC13671637 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36619 CCN1C(=O)C(Nc2ccc(OC)cc2)=C(C1=O)c1ccccc1 InChI=1S/C19H18N2O3/c1-3-21-18(22)16(13-7-5-4-6-8-13)17(19(21)23)20-14-9-11-15(24-2)12-10-14/h4-12,20H,3H2,1-2H3 XAQNYALTFTXDFC-UHFFFAOYSA-N 20159 1-ethyl-3-[(4-methoxyphenyl)amino]-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 7 Oxysterols receptor LXR-beta 200 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20159&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24768118 49688234 ZINC13671639 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36620 COc1ccc(cc1)N=C1C(C(=O)N(C1=O)c1ccccc1)c1ccccc1 InChI=1S/C23H18N2O3/c1-28-19-14-12-17(13-15-19)24-21-20(16-8-4-2-5-9-16)22(26)25(23(21)27)18-10-6-3-7-11-18/h2-15,20H,1H3 IVMIYZHBOTZWSL-UHFFFAOYSA-N 20160 3-[(4-methoxyphenyl)amino]-1,4-diphenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 8 Oxysterols receptor LXR-beta 260 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20160&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91895929 49688235 ZINC13671641 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36621 COc1ccc(NC2=C(C(=O)N(C)C2=O)c2ccccc2)cc1 InChI=1S/C18H16N2O3/c1-20-17(21)15(12-6-4-3-5-7-12)16(18(20)22)19-13-8-10-14(23-2)11-9-13/h3-11,19H,1-2H3 SRRMALAKIVOBLG-UHFFFAOYSA-N 20161 3-[(4-methoxyphenyl)amino]-1-methyl-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 9 Oxysterols receptor LXR-beta 300 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20161&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24768120 49688236 ZINC13671643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36622 CCN1C(=O)C(Nc2ccccc2)=C(C1=O)c1ccccc1 InChI=1S/C18H16N2O2/c1-2-20-17(21)15(13-9-5-3-6-10-13)16(18(20)22)19-14-11-7-4-8-12-14/h3-12,19H,2H2,1H3 UWSUYWGSXYIDQX-UHFFFAOYSA-N 20162 1-ethyl-3-phenyl-4-(phenylamino)-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 10 Oxysterols receptor LXR-beta 560 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20162&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24768121 49688237 ZINC13671645 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36623 CCN1C(=O)C(Nc2ccc(Cl)cc2)=C(C1=O)c1ccccc1 InChI=1S/C18H15ClN2O2/c1-2-21-17(22)15(12-6-4-3-5-7-12)16(18(21)23)20-14-10-8-13(19)9-11-14/h3-11,20H,2H2,1H3 SFMSQWAOWRDRJX-UHFFFAOYSA-N 20163 3-[(4-chlorophenyl)amino]-1-ethyl-4-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione::GSK3987 Analogue::Substituted Maleimide, 11 Oxysterols receptor LXR-beta 575 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20163&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24768122 49688238 ZINC13671647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36624 CN1C(=O)C(Nc2ccccc2)=C(C1=O)c1ccccc1 InChI=1S/C17H14N2O2/c1-19-16(20)14(12-8-4-2-5-9-12)15(17(19)21)18-13-10-6-3-7-11-13/h2-11,18H,1H3 VHMAXOKYWIMGCU-UHFFFAOYSA-N 8293 1-methyl-3-phenyl-4-(phenylamino)-2,5-dihydro-1H-pyrrole-2,5-dione::4-arylmaleimide deriv. 9a::JMC485419 Compound 12 Oxysterols receptor LXR-beta 850 7.5 22.00 C Curated from the literature by BindingDB 10.1021/jm050532w 10.7270/Q26T0JXG 16107141 aid1797957 Jaye, MC; Krawiec, JA; Campobasso, N; Smallwood, A; Qiu, C; Lu, Q; Kerrigan, JJ; De Los Frailes Alvaro, M; Laffitte, B; Liu, WS; Marino, JP; Meyer, CR; Nichols, JA; Parks, DJ; Perez, P; Sarov-Blat, L; Seepersaud, SD; Steplewski, KM; Thompson, SK; Wang, P; Watson, MA; Webb, CL; Haigh, D; Caravella, JA; Macphee, CH; Willson, TM; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8293&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6539523 11109046 ZINC13671649 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43311 OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 LXBIFEVIBLOUGU-JGWLITMVSA-N 18351 (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol, 10::(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol::1-Deoxynojirimycin::1-deoxynojirimycin (DNJ)::CHEMBL307429::US9181184, 1::dNM Oxysterols receptor LXR-beta >100000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18351&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search DNJ 1DIE,1DOG,1I75,1OIM,2J77,2JKE,2PWD,3GBE,3GXT 29435 46518429 44369 CHEMBL307429 4642 C16843 ZINC03794714 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43312 Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H TZBJGXHYKVUXJN-UHFFFAOYSA-N 19459 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one::CHEMBL44::Genistein::Genistein, 8::Genisteol::Prunetol::US8552057, 2::cid_5280961 Oxysterols receptor LXR-beta 22000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19459&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search GEN 1X7J,1X7R,5AV4,5AUZ,3KGU,3KGT,2QA8,1QKM,6G8G,4FJ1,5KDA,7NFB 5280961 46519480 28088 CHEMBL44 DB01645 2826 C06563 ZINC18825330 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43313 O=C1N(C(=O)c2ccccc12)c1ccccc1CCc1ccccc1 InChI=1S/C22H17NO2/c24-21-18-11-5-6-12-19(18)22(25)23(21)20-13-7-4-10-17(20)15-14-16-8-2-1-3-9-16/h1-13H,14-15H2 XGSWAPNRKGOSKD-UHFFFAOYSA-N 23840 2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindole-1,3-dione::CHEMBL246144::PP2P Oxysterols receptor LXR-beta 44000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23840&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10616182 50092092 CHEMBL246144 ZINC28898291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43314 CCCCCCc1ccccc1N1C(=O)c2ccccc2C1=O InChI=1S/C20H21NO2/c1-2-3-4-5-10-15-11-6-9-14-18(15)21-19(22)16-12-7-8-13-17(16)20(21)23/h6-9,11-14H,2-5,10H2,1H3 USXHUJLIZBGCGH-UHFFFAOYSA-N 23841 2-(2-hexylphenyl)-2,3-dihydro-1H-isoindole-1,3-dione::CHEMBL245943::PP60 Oxysterols receptor LXR-beta 65000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23841&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10638446 50092093 CHEMBL245943 ZINC28898280 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43315 CC(C)c1cccc(C(C)C)c1N1C(=O)c2ccccc2C1=S InChI=1S/C20H21NOS/c1-12(2)14-10-7-11-15(13(3)4)18(14)21-19(22)16-8-5-6-9-17(16)20(21)23/h5-13H,1-4H3 NLSLEAPXLGIRCU-UHFFFAOYSA-N 23842 2-[2,6-bis(propan-2-yl)phenyl]-3-sulfanylidene-2,3-dihydro-1H-isoindol-1-one::CHEMBL329471::PPS-33 Oxysterols receptor LXR-beta 18000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23842&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10064801 50092094 CHEMBL329471 ZINC00023409 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43316 Oc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2c(O)c5)ccc4O)cc3)c1 InChI=1S/C28H24O4/c29-22-9-13-24-21(17-22)8-3-18-4-10-23(11-5-18)32-28-16-20(7-14-26(28)30)2-1-19-6-12-25(24)27(31)15-19/h4-7,9-17,29-31H,1-3,8H2 JMKSVONWZFVEAI-UHFFFAOYSA-N 23839 14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(25),2(7),3,5,10,12,15,17,19(27),22(26),23,28-dodecaene-5,16,24-triol::Riccardin C Oxysterols receptor LXR-beta 6600 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23839&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10070992 50092091 ZINC14687268 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43317 COc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2c(OC)c5)ccc4OC)cc3)c1 InChI=1S/C31H30O4/c1-32-26-14-16-27-24(20-26)11-6-21-7-12-25(13-8-21)35-31-19-23(10-17-29(31)33-2)5-4-22-9-15-28(27)30(18-22)34-3/h7-10,12-20H,4-6,11H2,1-3H3 CDFKRQXFXHECQG-UHFFFAOYSA-N 23843 5,16,25-trimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 19a Oxysterols receptor LXR-beta 14000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23843&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10528213 50092095 ZINC29124357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43318 COc1ccc2CCc3ccc(c(OC)c3)-c3ccccc3CCc3ccc(Oc1c2)cc3 InChI=1S/C30H28O3/c1-31-28-18-13-23-8-7-22-12-17-27(29(19-22)32-2)26-6-4-3-5-24(26)14-9-21-10-15-25(16-11-21)33-30(28)20-23/h3-6,10-13,15-20H,7-9,14H2,1-2H3 BXLSIUXUNIEEJB-UHFFFAOYSA-N 23844 16,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 19b Oxysterols receptor LXR-beta 12000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23844&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860506 50092096 ZINC29124351 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43319 COc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2cc5)ccc4OC)cc3)c1 InChI=1S/C30H28O3/c1-31-27-16-17-28-24-11-5-21(6-12-24)3-4-23-10-18-29(32-2)30(19-23)33-26-14-8-22(9-15-26)7-13-25(28)20-27/h5-6,8-12,14-20H,3-4,7,13H2,1-2H3 HMOXHHMJBYTUJK-UHFFFAOYSA-N 23845 5,16-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 19c Oxysterols receptor LXR-beta 26000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23845&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860507 50092097 ZINC29124353 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43320 COc1ccc-2c(CCc3ccc(Oc4cccc(CCc5ccc-2c(OC)c5)c4)cc3)c1 InChI=1S/C30H28O3/c1-31-26-15-17-28-24(20-26)12-8-21-9-13-25(14-10-21)33-27-5-3-4-22(18-27)6-7-23-11-16-29(28)30(19-23)32-2/h3-5,9-11,13-20H,6-8,12H2,1-2H3 GLTFSJARKJFXDI-UHFFFAOYSA-N 23846 5,25-dimethoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 19d Oxysterols receptor LXR-beta 46000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23846&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860508 50092098 ZINC29124309 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43321 COc1ccc2CCc3ccc(cc3)-c3ccccc3CCc3ccc(Oc1c2)cc3 InChI=1S/C29H26O2/c1-30-28-19-13-23-7-6-21-9-15-25(16-10-21)27-5-3-2-4-24(27)14-8-22-11-17-26(18-12-22)31-29(28)20-23/h2-5,9-13,15-20H,6-8,14H2,1H3 KPPHKUBDCAKMJR-UHFFFAOYSA-N 23847 16-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 19e Oxysterols receptor LXR-beta 41000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23847&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860509 50092099 ZINC29124311 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43322 COc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3 InChI=1S/C29H26O2/c1-30-29-20-23-10-9-22-5-4-7-26(19-22)31-25-16-12-21(13-17-25)11-15-24-6-2-3-8-27(24)28(29)18-14-23/h2-8,12-14,16-20H,9-11,15H2,1H3 UYGWEAIWBIKKSH-UHFFFAOYSA-N 23848 25-methoxy-14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 19f Oxysterols receptor LXR-beta 11000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23848&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860510 50092100 ZINC29124305 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43323 Oc1ccc2CCc3ccc(c(O)c3)-c3ccccc3CCc3ccc(Oc1c2)cc3 InChI=1S/C28H24O3/c29-26-16-11-21-6-5-20-10-15-25(27(30)17-20)24-4-2-1-3-22(24)12-7-19-8-13-23(14-9-19)31-28(26)18-21/h1-4,8-11,13-18,29-30H,5-7,12H2 OAEVJFPPXJHCKV-UHFFFAOYSA-N 23849 14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(25),2(7),3,5,10,12,15,17,19(27),22(26),23,28-dodecaene-16,24-diol::Riccardin C derivative, 20b Oxysterols receptor LXR-beta 13000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23849&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860511 50092101 ZINC29124307 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43324 Oc1ccc-2c(CCc3ccc(Oc4cc(CCc5ccc-2cc5)ccc4O)cc3)c1 InChI=1S/C28H24O3/c29-24-12-15-26-22-9-3-19(4-10-22)1-2-21-8-16-27(30)28(17-21)31-25-13-6-20(7-14-25)5-11-23(26)18-24/h3-4,6-10,12-18,29-30H,1-2,5,11H2 VSXIMYQGZUVRSK-UHFFFAOYSA-N 23850 14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene-5,16-diol::Riccardin C derivative, 20c Oxysterols receptor LXR-beta 7600 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23850&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860512 50092102 ZINC29124263 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43325 Oc1ccc-2c(CCc3ccc(Oc4cccc(CCc5ccc-2c(O)c5)c4)cc3)c1 InChI=1S/C28H24O3/c29-23-11-15-26-22(18-23)10-6-19-7-12-24(13-8-19)31-25-3-1-2-20(16-25)4-5-21-9-14-27(26)28(30)17-21/h1-3,7-9,11-18,29-30H,4-6,10H2 ZCEPVFMKRVLFDX-UHFFFAOYSA-N 23851 14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(25),2(7),3,5,10,12,15,17,19(27),22(26),23,28-dodecaene-5,24-diol::Riccardin C derivative, 20d Oxysterols receptor LXR-beta 10000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23851&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860513 50092103 ZINC29124248 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43326 Oc1ccc2CCc3ccc(cc3)-c3ccccc3CCc3ccc(Oc1c2)cc3 InChI=1S/C28H24O2/c29-27-18-12-22-6-5-20-8-14-24(15-9-20)26-4-2-1-3-23(26)13-7-21-10-16-25(17-11-21)30-28(27)19-22/h1-4,8-12,14-19,29H,5-7,13H2 CTGIBRGBEVEPID-UHFFFAOYSA-N 23852 14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaen-16-ol::Riccardin C derivative, 20e Oxysterols receptor LXR-beta 14000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23852&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860514 50092104 ZINC29124181 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43327 Oc1cc2CCc3cccc(Oc4ccc(CCc5ccccc5-c1cc2)cc4)c3 InChI=1S/C28H24O2/c29-28-19-22-9-8-21-4-3-6-25(18-21)30-24-15-11-20(12-16-24)10-14-23-5-1-2-7-26(23)27(28)17-13-22/h1-7,11-13,15-19,29H,8-10,14H2 AWANYYTXBZWDHH-UHFFFAOYSA-N 23853 14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(25),2(7),3,5,10,12,15,17,19(27),22(26),23,28-dodecaen-24-ol::Riccardin C derivative, 20f Oxysterols receptor LXR-beta 7300 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23853&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860515 50092105 ZINC29124179 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 43328 C1Cc2cccc(Oc3ccc(CCc4ccccc4-c4ccc1cc4)cc3)c2 InChI=1S/C28H24O/c1-2-7-28-24(5-1)15-10-22-13-18-26(19-14-22)29-27-6-3-4-23(20-27)9-8-21-11-16-25(28)17-12-21/h1-7,11-14,16-20H,8-10,15H2 VHGMCOKOKWHSEA-UHFFFAOYSA-N 23854 14-oxapentacyclo[20.2.2.2^{10,13}.1^{15,19}.0^{2,7}]nonacosa-1(24),2(7),3,5,10,12,15,17,19(27),22,25,28-dodecaene::Riccardin C derivative, 22 Oxysterols receptor LXR-beta 77000 Curated from the literature by BindingDB 10.1016/j.bmc.2008.02.078 10.7270/Q28S4N7J 18343126 aid1798364 Dodo, K; Aoyama, A; Noguchi-Yachide, T; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23854&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24860516 50092106 ZINC29124129 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49830 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 25 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49831 Cc1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)[nH]n1 InChI=1S/C29H29ClF3N3O/c1-21-18-27(35-34-21)37-17-9-16-36(19-24-14-8-15-26(28(24)30)29(31,32)33)20-25(22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-8,10-15,18,25H,9,16-17,19-20H2,1H3,(H,34,35) JLMNPTOCKBOBJT-UHFFFAOYSA-N 27164 1H-indol-1-yl tertiary amine, 8::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl){3-[(5-methyl-1H-pyrazol-3-yl)oxy]propyl}amine Oxysterols receptor LXR-beta 15 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27164&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11489411 57298874 ZINC40402948 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49832 COC(=O)c1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)no1 InChI=1S/C30H28ClF3N2O4/c1-38-29(37)26-18-27(35-40-26)39-17-9-16-36(19-23-14-8-15-25(28(23)31)30(32,33)34)20-24(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-8,10-15,18,24H,9,16-17,19-20H2,1H3 UMYHRDJPCVNPPU-UHFFFAOYSA-N 27165 1H-indol-1-yl tertiary amine, 9::methyl 3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1,2-oxazole-5-carboxylate Oxysterols receptor LXR-beta 26 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27165&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11180636 57298875 ZINC42877029 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49833 FC(F)(F)c1cccc(CN(CCCOc2n[nH]c3ccccc23)CC(c2ccccc2)c2ccccc2)c1Cl InChI=1S/C32H29ClF3N3O/c33-30-25(15-9-17-28(30)32(34,35)36)21-39(19-10-20-40-31-26-16-7-8-18-29(26)37-38-31)22-27(23-11-3-1-4-12-23)24-13-5-2-6-14-24/h1-9,11-18,27H,10,19-22H2,(H,37,38) JFYYICQUPIPHLA-UHFFFAOYSA-N 27166 1H-indol-1-yl tertiary amine, 10::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indazol-3-yloxy)propyl]amine Oxysterols receptor LXR-beta 60 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27166&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190753 57298876 ZINC49867477 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49834 Cc1cc(C)c2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)n[nH]c2n1 InChI=1S/C33H32ClF3N4O/c1-22-19-23(2)38-31-29(22)32(40-39-31)42-18-10-17-41(20-26-15-9-16-28(30(26)34)33(35,36)37)21-27(24-11-5-3-6-12-24)25-13-7-4-8-14-25/h3-9,11-16,19,27H,10,17-18,20-21H2,1-2H3,(H,38,39,40) UIUZIKMYVPKHET-UHFFFAOYSA-N 27167 1H-indol-1-yl tertiary amine, 11::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}[3-({4,6-dimethyl-1H-pyrazolo[3,4-b]pyridin-3-yl}oxy)propyl](2,2-diphenylethyl)amine Oxysterols receptor LXR-beta 510 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27167&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190754 57298877 ZINC44350726 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49835 Cc1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)n2ncnc2n1 InChI=1S/C31H29ClF3N5O/c1-22-18-28(40-30(38-22)36-21-37-40)41-17-9-16-39(19-25-14-8-15-27(29(25)32)31(33,34)35)20-26(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-8,10-15,18,21,26H,9,16-17,19-20H2,1H3 GQKJTVVPKFBCQQ-UHFFFAOYSA-N 27168 1H-indol-1-yl tertiary amine, 12::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl){3-[(5-methyl-1,3,4,8000000-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)oxy]propyl}amine Oxysterols receptor LXR-beta 560 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27168&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91663364 57298878 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49836 COC(=O)Cc1c[nH]c2ccc(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cc12 InChI=1S/C36H34ClF3N2O3/c1-44-34(43)20-28-22-41-33-17-16-29(21-30(28)33)45-19-9-18-42(23-27-14-8-15-32(35(27)37)36(38,39)40)24-31(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-8,10-17,21-22,31,41H,9,18-20,23-24H2,1H3 QCPMSPLCIPCOOQ-UHFFFAOYSA-N 27169 1H-indol-1-yl tertiary amine, 13::methyl 2-{5-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1H-indol-3-yl}acetate Oxysterols receptor LXR-beta 288 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27169&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190755 57298879 ZINC49889460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49837 FC(F)(F)c1cccc(CN(CCCOc2ccc3[nH]ccc3c2)CC(c2ccccc2)c2ccccc2)c1Cl InChI=1S/C33H30ClF3N2O/c34-32-27(13-7-14-30(32)33(35,36)37)22-39(19-8-20-40-28-15-16-31-26(21-28)17-18-38-31)23-29(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-7,9-18,21,29,38H,8,19-20,22-23H2 JVBLJBOHCQRKTI-UHFFFAOYSA-N 27170 1H-indol-1-yl tertiary amine, 14::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-5-yloxy)propyl]amine Oxysterols receptor LXR-beta 23 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27170&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190756 57298880 ZINC42875435 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49838 FC(F)(F)c1cccc(CN(CCCOc2cccc3[nH]ccc23)CC(c2ccccc2)c2ccccc2)c1Cl InChI=1S/C33H30ClF3N2O/c34-32-26(14-7-15-29(32)33(35,36)37)22-39(20-9-21-40-31-17-8-16-30-27(31)18-19-38-30)23-28(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-8,10-19,28,38H,9,20-23H2 FSENUVJQKQCYBD-UHFFFAOYSA-N 27171 1H-indol-1-yl tertiary amine, 15::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indol-4-yloxy)propyl]amine Oxysterols receptor LXR-beta 15 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27171&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190757 57298881 ZINC44360473 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49839 Cn1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 InChI=1S/C34H32ClF3N2O/c1-39-21-19-28-31(39)17-9-18-32(28)41-22-10-20-40(23-27-15-8-16-30(33(27)35)34(36,37)38)24-29(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-9,11-19,21,29H,10,20,22-24H2,1H3 YBVHXCRCXDFGNF-UHFFFAOYSA-N 27172 1H-indol-1-yl tertiary amine, 16::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl){3-[(1-methyl-1H-indol-4-yl)oxy]propyl}amine Oxysterols receptor LXR-beta 12 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27172&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11273187 57298882 ZINC42835481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49840 CS(=O)(=O)n1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 InChI=1S/C34H32ClF3N2O3S/c1-44(41,42)40-21-19-28-31(40)17-9-18-32(28)43-22-10-20-39(23-27-15-8-16-30(33(27)35)34(36,37)38)24-29(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-9,11-19,21,29H,10,20,22-24H2,1H3 PMNRZVRQMPJDNZ-UHFFFAOYSA-N 27173 1H-indol-1-yl tertiary amine, 17::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl){3-[(1-methanesulfonyl-1H-indol-4-yl)oxy]propyl}amine Oxysterols receptor LXR-beta 7 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27173&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11377209 57298883 ZINC49898232 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 49841 OC(=O)Cn1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 InChI=1S/C35H32ClF3N2O3/c36-34-27(14-7-15-30(34)35(37,38)39)22-40(23-29(25-10-3-1-4-11-25)26-12-5-2-6-13-26)19-9-21-44-32-17-8-16-31-28(32)18-20-41(31)24-33(42)43/h1-8,10-18,20,29H,9,19,21-24H2,(H,42,43) RHWNXOWPCIQOAH-UHFFFAOYSA-N 27174 1H-indol-1-yl tertiary amine, 18::2-{4-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]-1H-indol-1-yl}acetic acid Oxysterols receptor LXR-beta 4 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.004 10.7270/Q28W3BMD 19167885 aid1798783 Washburn, DG; Hoang, TH; Campobasso, N; Smallwood, A; Parks, DJ; Webb, CL; Frank, KA; Nord, M; Duraiswami, C; Evans, C; Jaye, M; Thompson, SK GSK http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27174&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search LX2 3FC6 25147499 57298884 ZINC39716198 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50017 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3 ODJWHQQYADUVIQ-UHFFFAOYSA-N 27251 indan derivative, 1::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 190 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27251&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190792 57298960 ZINC28822967 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50018 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1cccc(CCNS(=O)(=O)c2ccccc2)c1 InChI=1S/C27H28N2O4S/c1-27(2,3)33-26(30)29-24-15-8-7-11-22(24)19-25(29)21-12-9-10-20(18-21)16-17-28-34(31,32)23-13-5-4-6-14-23/h4-15,18-19,28H,16-17H2,1-3H3 ITARVGIWSLJAAL-UHFFFAOYSA-N 27252 Boc-indole derivative, 10::tert-butyl 2-[3-(2-benzenesulfonamidoethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 420 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27252&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190793 57298961 ZINC28822968 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50019 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCNS(=O)(=O)c2ccccc2)cc1 InChI=1S/C27H28N2O4S/c1-27(2,3)33-26(30)29-24-12-8-7-9-22(24)19-25(29)21-15-13-20(14-16-21)17-18-28-34(31,32)23-10-5-4-6-11-23/h4-16,19,28H,17-18H2,1-3H3 XIHLOKCAGFEWSY-UHFFFAOYSA-N 27253 Boc-indole derivative, 11::tert-butyl 2-[4-(2-benzenesulfonamidoethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 120 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27253&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190794 57298962 ZINC28822970 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50020 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CNS(=O)(=O)c2ccccc2)cc1 InChI=1S/C26H26N2O4S/c1-26(2,3)32-25(29)28-23-12-8-7-9-21(23)17-24(28)20-15-13-19(14-16-20)18-27-33(30,31)22-10-5-4-6-11-22/h4-17,27H,18H2,1-3H3 CLECJEAZJQUVHR-UHFFFAOYSA-N 27254 Boc-indole derivative, 12::tert-butyl 2-[4-(benzenesulfonamidomethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 220 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27254&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190795 57298963 ZINC28822971 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50021 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCCNS(=O)(=O)c2ccccc2)cc1 InChI=1S/C28H30N2O4S/c1-28(2,3)34-27(31)30-25-14-8-7-11-23(25)20-26(30)22-17-15-21(16-18-22)10-9-19-29-35(32,33)24-12-5-4-6-13-24/h4-8,11-18,20,29H,9-10,19H2,1-3H3 ZBNPFNJMAUUSGZ-UHFFFAOYSA-N 27255 Boc-indole derivative, 13::tert-butyl 2-[4-(3-benzenesulfonamidopropyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 350 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27255&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190796 57298964 ZINC28822973 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50022 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(NS(=O)(=O)c2ccccc2)cc1 InChI=1S/C25H24N2O4S/c1-25(2,3)31-24(28)27-22-12-8-7-9-19(22)17-23(27)18-13-15-20(16-14-18)26-32(29,30)21-10-5-4-6-11-21/h4-17,26H,1-3H3 IBYNZVLBKSXPHL-UHFFFAOYSA-N 27256 Boc-indole derivative, 14::tert-butyl 2-(4-benzenesulfonamidophenyl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1320 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27256&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190797 57298965 ZINC28822974 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50023 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCNS(=O)(=O)c2cccs2)cc1 InChI=1S/C25H26N2O4S2/c1-25(2,3)31-24(28)27-21-8-5-4-7-20(21)17-22(27)19-12-10-18(11-13-19)14-15-26-33(29,30)23-9-6-16-32-23/h4-13,16-17,26H,14-15H2,1-3H3 UKWZKSRAHQOEFY-UHFFFAOYSA-N 27257 Boc-indole derivative, 15::tert-butyl 2-{4-[2-(thiophene-2-sulfonamido)ethyl]phenyl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 58 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27257&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190798 57298966 ZINC28822976 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50024 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCNS(=O)(=O)c2ccc(s2)-c2ccccn2)cc1 InChI=1S/C30H29N3O4S2/c1-30(2,3)37-29(34)33-25-10-5-4-8-23(25)20-26(33)22-13-11-21(12-14-22)17-19-32-39(35,36)28-16-15-27(38-28)24-9-6-7-18-31-24/h4-16,18,20,32H,17,19H2,1-3H3 SGIRNEGPFZYLSL-UHFFFAOYSA-N 27258 Boc-indole derivative, 16::tert-butyl 2-[4-(2-{[5-(pyridin-2-yl)thiophene-2-]sulfonamido}ethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 230 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27258&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190799 57298967 ZINC59029487 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50025 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CNC(=O)c2ccccc2)cc1 InChI=1S/C27H26N2O3/c1-27(2,3)32-26(31)29-23-12-8-7-11-22(23)17-24(29)20-15-13-19(14-16-20)18-28-25(30)21-9-5-4-6-10-21/h4-17H,18H2,1-3H3,(H,28,30) DRJQMKWIDPDWOD-UHFFFAOYSA-N 27259 Boc-indole derivative, 17::tert-butyl 2-{4-[(phenylformamido)methyl]phenyl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1800 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27259&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190800 57298968 ZINC28822979 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50026 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCNC(=O)c2ccccc2)cc1 InChI=1S/C28H28N2O3/c1-28(2,3)33-27(32)30-24-12-8-7-11-23(24)19-25(30)21-15-13-20(14-16-21)17-18-29-26(31)22-9-5-4-6-10-22/h4-16,19H,17-18H2,1-3H3,(H,29,31) CANDDIRWDWFMQO-UHFFFAOYSA-N 27260 Boc-indole derivative, 18::tert-butyl 2-{4-[2-(phenylformamido)ethyl]phenyl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1750 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27260&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190801 57298969 ZINC28822980 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50027 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCCNC(=O)c2ccccc2)cc1 InChI=1S/C29H30N2O3/c1-29(2,3)34-28(33)31-25-14-8-7-13-24(25)20-26(31)22-17-15-21(16-18-22)10-9-19-30-27(32)23-11-5-4-6-12-23/h4-8,11-18,20H,9-10,19H2,1-3H3,(H,30,32) YUMVVYLDGGAYSE-UHFFFAOYSA-N 27261 Boc-indole derivative, 19::tert-butyl 2-{4-[3-(phenylformamido)propyl]phenyl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 360 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27261&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190802 57298970 ZINC28822981 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50028 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CN)cc1 InChI=1S/C20H22N2O2/c1-20(2,3)24-19(23)22-17-7-5-4-6-16(17)12-18(22)15-10-8-14(13-21)9-11-15/h4-12H,13,21H2,1-3H3 GBUXJHHZGCVCOF-UHFFFAOYSA-N 27262 Boc-indole derivative, 20::tert-butyl 2-[4-(aminomethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 5600 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27262&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190803 57298971 ZINC28822982 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50029 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CC#N)cc1 InChI=1S/C21H20N2O2/c1-21(2,3)25-20(24)23-18-7-5-4-6-17(18)14-19(23)16-10-8-15(9-11-16)12-13-22/h4-11,14H,12H2,1-3H3 USXVGBNPSOPVMP-UHFFFAOYSA-N 27263 Boc-indole derivative, 21::tert-butyl 2-[4-(cyanomethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 300 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27263&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190804 57298972 C04116 ZINC28822983 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50030 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCC#N)cc1 InChI=1S/C22H22N2O2/c1-22(2,3)26-21(25)24-19-9-5-4-8-18(19)15-20(24)17-12-10-16(11-13-17)7-6-14-23/h4-5,8-13,15H,6-7H2,1-3H3 DJJZHQMUPSIXOU-UHFFFAOYSA-N 27264 Boc-indole derivative, 22::tert-butyl 2-[4-(2-cyanoethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 130 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27264&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190805 57298973 ZINC28822984 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50031 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCCO)cc1 InChI=1S/C22H25NO3/c1-22(2,3)26-21(25)23-19-9-5-4-8-18(19)15-20(23)17-12-10-16(11-13-17)7-6-14-24/h4-5,8-13,15,24H,6-7,14H2,1-3H3 ARPXHHWSHWMMOR-UHFFFAOYSA-N 27265 Boc-indole derivative, 23::tert-butyl 2-[4-(3-hydroxypropyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 380 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27265&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190806 57298974 ZINC28822985 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50032 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(OCCO)cc1 InChI=1S/C21H23NO4/c1-21(2,3)26-20(24)22-18-7-5-4-6-16(18)14-19(22)15-8-10-17(11-9-15)25-13-12-23/h4-11,14,23H,12-13H2,1-3H3 JXAZDEXRLDFYHT-UHFFFAOYSA-N 27266 Boc-indole derivative, 24::tert-butyl 2-[4-(2-hydroxyethoxy)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 420 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27266&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190807 57298975 ZINC28822986 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50033 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCC(O)=O)cc1 InChI=1S/C22H23NO4/c1-22(2,3)27-21(26)23-18-7-5-4-6-17(18)14-19(23)16-11-8-15(9-12-16)10-13-20(24)25/h4-9,11-12,14H,10,13H2,1-3H3,(H,24,25) MKCFFUAMLVRSKU-UHFFFAOYSA-N 27267 3-(4-{1-[(tert-butoxy)carbonyl]-1H-indol-2-yl}phenyl)propanoic acid::Boc-indole derivative, 25 Oxysterols receptor LXR-beta 220 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27267&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190808 57298976 ZINC28822988 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50034 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCC(N)=O)cc1 InChI=1S/C22H24N2O3/c1-22(2,3)27-21(26)24-18-7-5-4-6-17(18)14-19(24)16-11-8-15(9-12-16)10-13-20(23)25/h4-9,11-12,14H,10,13H2,1-3H3,(H2,23,25) UGGWFWBEVUZUOW-UHFFFAOYSA-N 27268 Boc-indole derivative, 26::tert-butyl 2-[4-(2-carbamoylethyl)phenyl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 57 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27268&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190809 57298977 ZINC28822989 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50035 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(\C=C\C(N)=O)cc1 InChI=1S/C22H22N2O3/c1-22(2,3)27-21(26)24-18-7-5-4-6-17(18)14-19(24)16-11-8-15(9-12-16)10-13-20(23)25/h4-14H,1-3H3,(H2,23,25)/b13-10+ GNZNNFALCSHPDY-JLHYYAGUSA-N 27269 Boc-indole derivative, 27::tert-butyl 2-{4-[(1E)-2-carbamoyleth-1-en-1-yl]phenyl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 4900 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27269&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190810 57298978 ZINC28822990 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50036 CNC(=O)CCc1ccc(cc1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C23H26N2O3/c1-23(2,3)28-22(27)25-19-8-6-5-7-18(19)15-20(25)17-12-9-16(10-13-17)11-14-21(26)24-4/h5-10,12-13,15H,11,14H2,1-4H3,(H,24,26) YTOCQJJZBNKKDQ-UHFFFAOYSA-N 27270 Boc-indole derivative, 28::tert-butyl 2-{4-[2-(methylcarbamoyl)ethyl]phenyl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 490 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27270&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190811 57298979 ZINC28822991 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50037 CC(C)CNC(=O)CCc1ccc(cc1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C26H32N2O3/c1-18(2)17-27-24(29)15-12-19-10-13-20(14-11-19)23-16-21-8-6-7-9-22(21)28(23)25(30)31-26(3,4)5/h6-11,13-14,16,18H,12,15,17H2,1-5H3,(H,27,29) TWKMYSHUTIQTCV-UHFFFAOYSA-N 27271 Boc-indole derivative, 29::tert-butyl 2-(4-{2-[(2-methylpropyl)carbamoyl]ethyl}phenyl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1510 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27271&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190812 57298980 ZINC28822992 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50038 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc(CCC(=O)Nc2ccccc2)cc1 InChI=1S/C28H28N2O3/c1-28(2,3)33-27(32)30-24-12-8-7-9-22(24)19-25(30)21-16-13-20(14-17-21)15-18-26(31)29-23-10-5-4-6-11-23/h4-14,16-17,19H,15,18H2,1-3H3,(H,29,31) CWWNQIXWUGATTK-UHFFFAOYSA-N 27272 Boc-indole derivative, 30::tert-butyl 2-{4-[2-(phenylcarbamoyl)ethyl]phenyl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1780 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27272&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190813 57298981 ZINC28822993 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50039 O=C(c1ccccc1)n1c(cc2ccccc12)-c1ccc(CCC#N)cc1 InChI=1S/C24H18N2O/c25-16-6-7-18-12-14-19(15-13-18)23-17-21-10-4-5-11-22(21)26(23)24(27)20-8-2-1-3-9-20/h1-5,8-15,17H,6-7H2 QTTITSQRAWWOBG-UHFFFAOYSA-N 27273 3-[4-(1-benzoyl-1H-indol-2-yl)phenyl]propanenitrile::benzamide derivative, 8 Oxysterols receptor LXR-beta 12 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27273&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16725052 57298982 ZINC28822994 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50040 O=C(NCCc1ccc(cc1)-c1cc2ccccc2n1C(=O)c1ccccc1)c1ccccc1 InChI=1S/C30H24N2O2/c33-29(24-9-3-1-4-10-24)31-20-19-22-15-17-23(18-16-22)28-21-26-13-7-8-14-27(26)32(28)30(34)25-11-5-2-6-12-25/h1-18,21H,19-20H2,(H,31,33) NUXVHTUSPPVIQJ-UHFFFAOYSA-N 27274 N-{2-[4-(1-benzoyl-1H-indol-2-yl)phenyl]ethyl}benzamide::benzamide derivative, 9 Oxysterols receptor LXR-beta 1780 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27274&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190814 57298983 ZINC28822995 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50048 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 35 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50049 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 15 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.06.017 10.7270/Q2N58JQ9 17587573 aid1798792 Kher, S; Lake, K; Sircar, I; Pannala, M; Bakir, F; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50050 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3 ODJWHQQYADUVIQ-UHFFFAOYSA-N 27251 indan derivative, 1::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 210 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27251&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190792 57298960 ZINC28822967 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50051 CC(C)(C)OC(=O)n1c(cc2c(O)cccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H28N2O5S/c1-28(2,3)35-27(32)30-24-10-7-11-26(31)23(24)17-25(30)19-13-12-18-15-21(16-20(18)14-19)29-36(33,34)22-8-5-4-6-9-22/h4-14,17,21,29,31H,15-16H2,1-3H3 VPKQELIIELQIKH-UHFFFAOYSA-N 27275 indole derivative, 1a::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-indole-1-carboxylate Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27275&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190815 57298984 ZINC28949427 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50052 CC(C)(C)OC(=O)n1c(cc2c(OCc3ccccc3)cccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C35H34N2O5S/c1-35(2,3)42-34(38)37-31-15-10-16-33(41-23-24-11-6-4-7-12-24)30(31)22-32(37)26-18-17-25-20-28(21-27(25)19-26)36-43(39,40)29-13-8-5-9-14-29/h4-19,22,28,36H,20-21,23H2,1-3H3 WIYXNJLKNMNODU-UHFFFAOYSA-N 27276 indole derivative, 1b::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-4-(benzyloxy)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27276&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190816 57298985 ZINC28949432 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50053 CC(C)(C)OC(=O)n1c(cc2cc(O)ccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H28N2O5S/c1-28(2,3)35-27(32)30-25-12-11-23(31)16-21(25)17-26(30)19-10-9-18-14-22(15-20(18)13-19)29-36(33,34)24-7-5-4-6-8-24/h4-13,16-17,22,29,31H,14-15H2,1-3H3 GPMOKHWGTGSTLL-UHFFFAOYSA-N 27277 indole derivative, 1c::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-5-hydroxy-1H-indole-1-carboxylate Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27277&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190817 57298986 ZINC28949437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50054 CC(C)(C)OC(=O)n1c(cc2cc(OCc3ccccc3)ccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C35H34N2O5S/c1-35(2,3)42-34(38)37-32-17-16-30(41-23-24-10-6-4-7-11-24)21-28(32)22-33(37)26-15-14-25-19-29(20-27(25)18-26)36-43(39,40)31-12-8-5-9-13-31/h4-18,21-22,29,36H,19-20,23H2,1-3H3 HPLWSWRMSMTACS-UHFFFAOYSA-N 27278 indole derivative, 1d::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-5-(benzyloxy)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27278&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190818 57298987 ZINC28949441 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50055 CC(C)(C)OC(=O)n1c(cc2cc(F)ccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H27FN2O4S/c1-28(2,3)35-27(32)31-25-12-11-22(29)14-21(25)17-26(31)19-10-9-18-15-23(16-20(18)13-19)30-36(33,34)24-7-5-4-6-8-24/h4-14,17,23,30H,15-16H2,1-3H3 JNEJBGJOSRBXQZ-UHFFFAOYSA-N 27279 indole derivative, 1e::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-5-fluoro-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1500 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27279&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190819 57298988 ZINC28949445 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50056 CC(C)(C)OC(=O)n1c(cc2cc(ccc12)C#N)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-26-12-9-19(18-30)13-23(26)17-27(32)21-11-10-20-15-24(16-22(20)14-21)31-37(34,35)25-7-5-4-6-8-25/h4-14,17,24,31H,15-16H2,1-3H3 YPHIKMLTSIUXLS-UHFFFAOYSA-N 27280 indole derivative, 1f::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-5-cyano-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 26000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27280&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190820 57298989 ZINC28949450 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50057 COc1ccc2n(C(=O)OC(C)(C)C)c(cc2c1)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-26-13-12-24(35-4)17-22(26)18-27(31)20-11-10-19-15-23(16-21(19)14-20)30-37(33,34)25-8-6-5-7-9-25/h5-14,17-18,23,30H,15-16H2,1-4H3 RMXRRZGKCORVBU-UHFFFAOYSA-N 27281 indole derivative, 1g::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-5-methoxy-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 28000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27281&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190821 57298990 ZINC28949454 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50058 Cc1ccc2n(C(=O)OC(C)(C)C)c(cc2c1)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H30N2O4S/c1-19-10-13-26-23(14-19)18-27(31(26)28(32)35-29(2,3)4)21-12-11-20-16-24(17-22(20)15-21)30-36(33,34)25-8-6-5-7-9-25/h5-15,18,24,30H,16-17H2,1-4H3 VFPZJYHPFQWFMB-UHFFFAOYSA-N 27282 indole derivative, 1h::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-5-methyl-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 18000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27282&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190822 57298991 ZINC28949458 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50059 CC(C)(C)OC(=O)n1c(cc2ccc(OCc3ccccc3)cc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C35H34N2O5S/c1-35(2,3)42-34(38)37-32(21-27-16-17-30(22-33(27)37)41-23-24-10-6-4-7-11-24)26-15-14-25-19-29(20-28(25)18-26)36-43(39,40)31-12-8-5-9-13-31/h4-18,21-22,29,36H,19-20,23H2,1-3H3 UORPHNLUSNFHNJ-UHFFFAOYSA-N 27283 indole derivative, 1i::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-6-(benzyloxy)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27283&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190823 57298992 ZINC28949461 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50060 COc1ccc2cc(-c3ccc4CC(Cc4c3)NS(=O)(=O)c3ccccc3)n(C(=O)OC(C)(C)C)c2c1 InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-26(17-21-12-13-24(35-4)18-27(21)31)20-11-10-19-15-23(16-22(19)14-20)30-37(33,34)25-8-6-5-7-9-25/h5-14,17-18,23,30H,15-16H2,1-4H3 BGFSCEOUOQETMV-UHFFFAOYSA-N 27284 indole derivative, 1j::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-6-methoxy-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1600 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27284&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190824 57298993 ZINC28949466 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50061 Cc1ccc2cc(-c3ccc4CC(Cc4c3)NS(=O)(=O)c3ccccc3)n(C(=O)OC(C)(C)C)c2c1 InChI=1S/C29H30N2O4S/c1-19-10-11-22-18-27(31(26(22)14-19)28(32)35-29(2,3)4)21-13-12-20-16-24(17-23(20)15-21)30-36(33,34)25-8-6-5-7-9-25/h5-15,18,24,30H,16-17H2,1-4H3 CIHVDXSUTNSSRH-UHFFFAOYSA-N 27285 indole derivative, 1k::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-6-methyl-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 300 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27285&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190825 57298994 ZINC28949470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50062 CC(C)(C)OC(=O)n1c(cc2ccc(O)cc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H28N2O5S/c1-28(2,3)35-27(32)30-25(16-20-11-12-23(31)17-26(20)30)19-10-9-18-14-22(15-21(18)13-19)29-36(33,34)24-7-5-4-6-8-24/h4-13,16-17,22,29,31H,14-15H2,1-3H3 KYJBKJMDJLPNHY-UHFFFAOYSA-N 27286 indole derivative, 1l::tert-butyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-6-hydroxy-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 670 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27286&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190826 57298995 ZINC28949474 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50063 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2C[C@H](Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3/t23-/m1/s1 ODJWHQQYADUVIQ-HSZRJFAPSA-N 27287 indole derivative, 1m (R)::tert-butyl 2-[(2R)-2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 660 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27287&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190827 57298996 ZINC28822966 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50064 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2C[C@@H](Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3/t23-/m0/s1 ODJWHQQYADUVIQ-QHCPKHFHSA-N 27288 indole derivative, 1n (S)::tert-butyl 2-[(2S)-2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 130 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190828 57298997 ZINC28822967 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50065 O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2[nH]1)c1ccccc1 InChI=1S/C23H20N2O2S/c26-28(27,21-7-2-1-3-8-21)25-20-13-16-10-11-18(12-19(16)14-20)23-15-17-6-4-5-9-22(17)24-23/h1-12,15,20,24-25H,13-14H2 JGPPKFSZHLHEKV-UHFFFAOYSA-N 27289 N-[5-(1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]benzenesulfonamide::indole derivative, 6 Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27289&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190829 57298998 ZINC28949478 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50066 COC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C25H22N2O4S/c1-31-25(28)27-23-10-6-5-7-18(23)16-24(27)19-12-11-17-14-21(15-20(17)13-19)26-32(29,30)22-8-3-2-4-9-22/h2-13,16,21,26H,14-15H2,1H3 SHUFLHYMWNTOCX-UHFFFAOYSA-N 27290 indole derivative, 12::methyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27290&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190830 57298999 ZINC28949482 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50067 CCOC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C26H24N2O4S/c1-2-32-26(29)28-24-11-7-6-8-19(24)17-25(28)20-13-12-18-15-22(16-21(18)14-20)27-33(30,31)23-9-4-3-5-10-23/h3-14,17,22,27H,2,15-16H2,1H3 NIMFRIUMYBJXEB-UHFFFAOYSA-N 27291 ethyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate::indole derivative, 13 Oxysterols receptor LXR-beta 1600 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27291&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190831 57299000 ZINC28949486 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068 CC(C)CCOC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H30N2O4S/c1-20(2)14-15-35-29(32)31-27-11-7-6-8-22(27)19-28(31)23-13-12-21-17-25(18-24(21)16-23)30-36(33,34)26-9-4-3-5-10-26/h3-13,16,19-20,25,30H,14-15,17-18H2,1-2H3 QFWUXCWSEPJDMD-UHFFFAOYSA-N 27292 3-methylbutyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate::indole derivative, 14 Oxysterols receptor LXR-beta 1300 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27292&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190832 57299001 ZINC28949490 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50069 CC(C)(C)COC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H30N2O4S/c1-29(2,3)19-35-28(32)31-26-12-8-7-9-21(26)18-27(31)22-14-13-20-16-24(17-23(20)15-22)30-36(33,34)25-10-5-4-6-11-25/h4-15,18,24,30H,16-17,19H2,1-3H3 UTZBOEHRXWUQDC-UHFFFAOYSA-N 27293 2,2-dimethylpropyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate::indole derivative, 15 Oxysterols receptor LXR-beta 1400 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27293&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190833 57299002 ZINC28949495 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50070 CCCCC(C)COC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C31H34N2O4S/c1-3-4-10-22(2)21-37-31(34)33-29-14-9-8-11-24(29)20-30(33)25-16-15-23-18-27(19-26(23)17-25)32-38(35,36)28-12-6-5-7-13-28/h5-9,11-17,20,22,27,32H,3-4,10,18-19,21H2,1-2H3 NPYFWOGKIKIDOE-UHFFFAOYSA-N 27294 2-methylhexyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate::indole derivative, 16 Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27294&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190834 57299003 ZINC28949503 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071 O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1S(=O)(=O)c1ccccc1)c1ccccc1 InChI=1S/C29H24N2O4S2/c32-36(33,26-10-3-1-4-11-26)30-25-18-21-15-16-23(17-24(21)19-25)29-20-22-9-7-8-14-28(22)31(29)37(34,35)27-12-5-2-6-13-27/h1-17,20,25,30H,18-19H2 ONHJIXSTAYJGBY-UHFFFAOYSA-N 27295 N-{5-[1-(benzenesulfonyl)-1H-indol-2-yl]-2,3-dihydro-1H-inden-2-yl}benzenesulfonamide::indole derivative, 17 Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27295&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190835 57299004 ZINC28949507 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50072 O=C(CC1CC1)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C28H26N2O3S/c31-28(14-19-10-11-19)30-26-9-5-4-6-21(26)18-27(30)22-13-12-20-16-24(17-23(20)15-22)29-34(32,33)25-7-2-1-3-8-25/h1-9,12-13,15,18-19,24,29H,10-11,14,16-17H2 OCLUGKDGDSHUTF-UHFFFAOYSA-N 27296 N-{5-[1-(2-cyclopropylacetyl)-1H-indol-2-yl]-2,3-dihydro-1H-inden-2-yl}benzenesulfonamide::indole derivative, 18 Oxysterols receptor LXR-beta 1160 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27296&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190836 57299005 ZINC28949511 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50073 O=C(C1CCCC1)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H28N2O3S/c32-29(20-8-4-5-9-20)31-27-13-7-6-10-22(27)19-28(31)23-15-14-21-17-25(18-24(21)16-23)30-35(33,34)26-11-2-1-3-12-26/h1-3,6-7,10-16,19-20,25,30H,4-5,8-9,17-18H2 GOFKZQPHWQEKAE-UHFFFAOYSA-N 27297 N-[5-(1-cyclopentanecarbonyl-1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]benzenesulfonamide::indole derivative, 19 Oxysterols receptor LXR-beta 900 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27297&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190837 57299006 ZINC28949516 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50074 CCCCCC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H30N2O3S/c1-2-3-5-14-29(32)31-27-13-9-8-10-22(27)20-28(31)23-16-15-21-18-25(19-24(21)17-23)30-35(33,34)26-11-6-4-7-12-26/h4,6-13,15-17,20,25,30H,2-3,5,14,18-19H2,1H3 QFAYFGIEPQGOAP-UHFFFAOYSA-N 27298 N-[5-(1-hexanoyl-1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]benzenesulfonamide::indole derivative, 20 Oxysterols receptor LXR-beta 2100 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27298&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190838 57299007 ZINC28949520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50075 CC(C)(C)CC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H30N2O3S/c1-29(2,3)19-28(32)31-26-12-8-7-9-21(26)18-27(31)22-14-13-20-16-24(17-23(20)15-22)30-35(33,34)25-10-5-4-6-11-25/h4-15,18,24,30H,16-17,19H2,1-3H3 HMFYVUXCNMFRMS-UHFFFAOYSA-N 27299 N-{5-[1-(3,3-dimethylbutanoyl)-1H-indol-2-yl]-2,3-dihydro-1H-inden-2-yl}benzenesulfonamide::indole derivative, 21 Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190839 57299008 ZINC28949524 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50076 Cn1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C24H22N2O2S/c1-26-23-10-6-5-7-18(23)16-24(26)19-12-11-17-14-21(15-20(17)13-19)25-29(27,28)22-8-3-2-4-9-22/h2-13,16,21,25H,14-15H2,1H3 VCOMAOSFHGZPHP-UHFFFAOYSA-N 27300 N-[5-(1-methyl-1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]benzenesulfonamide::indole derivative, 22 Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27300&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190840 57299009 ZINC28949528 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50077 CC(C)(C)OC(=O)Cn1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1 InChI=1S/C29H30N2O4S/c1-29(2,3)35-28(32)19-31-26-12-8-7-9-21(26)18-27(31)22-14-13-20-16-24(17-23(20)15-22)30-36(33,34)25-10-5-4-6-11-25/h4-15,18,24,30H,16-17,19H2,1-3H3 ANROTCZUIDKWLG-UHFFFAOYSA-N 27301 indole derivative, 23::tert-butyl 2-[2-(2-benzenesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indol-1-yl]acetate Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27301&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190841 57299010 ZINC28949533 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50078 O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1CCCOCc1ccccc1)c1ccccc1 InChI=1S/C33H32N2O3S/c36-39(37,31-13-5-2-6-14-31)34-30-21-26-16-17-28(20-29(26)22-30)33-23-27-12-7-8-15-32(27)35(33)18-9-19-38-24-25-10-3-1-4-11-25/h1-8,10-17,20,23,30,34H,9,18-19,21-22,24H2 GKDJMWJPRTXIOW-UHFFFAOYSA-N 27302 N-(5-{1-[3-(benzyloxy)propyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)benzenesulfonamide::indole derivative, 24 Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27302&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190842 57299011 ZINC28949537 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50079 O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1Cc1ccccc1)c1ccccc1 InChI=1S/C30H26N2O2S/c33-35(34,28-12-5-2-6-13-28)31-27-18-23-15-16-25(17-26(23)19-27)30-20-24-11-7-8-14-29(24)32(30)21-22-9-3-1-4-10-22/h1-17,20,27,31H,18-19,21H2 XIZDVLOROQMCPV-UHFFFAOYSA-N 27303 N-[5-(1-benzyl-1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]benzenesulfonamide::indole derivative, 25 Oxysterols receptor LXR-beta >30000 7.5 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27303&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190843 57299012 ZINC28949542 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50080 COc1ccc(Cn2c(cc3ccccc23)-c2ccc3CC(Cc3c2)NS(=O)(=O)c2ccccc2)cc1 InChI=1S/C31H28N2O3S/c1-36-28-15-11-22(12-16-28)21-33-30-10-6-5-7-24(30)20-31(33)25-14-13-23-18-27(19-26(23)17-25)32-37(34,35)29-8-3-2-4-9-29/h2-17,20,27,32H,18-19,21H2,1H3 BVCXHWCCPVRXFJ-UHFFFAOYSA-N 27304 N-(5-{1-[(4-methoxyphenyl)methyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)benzenesulfonamide::indole derivative, 26 Oxysterols receptor LXR-beta >30000 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27304&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190844 57299013 ZINC28949547 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50081 O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1CCc1ccccc1)c1ccccc1 InChI=1S/C31H28N2O2S/c34-36(35,29-12-5-2-6-13-29)32-28-20-24-15-16-26(19-27(24)21-28)31-22-25-11-7-8-14-30(25)33(31)18-17-23-9-3-1-4-10-23/h1-16,19,22,28,32H,17-18,20-21H2 HFJFDLQVZPHGMA-UHFFFAOYSA-N 27305 N-{5-[1-(2-phenylethyl)-1H-indol-2-yl]-2,3-dihydro-1H-inden-2-yl}benzenesulfonamide::indole derivative, 27 Oxysterols receptor LXR-beta >10000 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27305&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190845 57299014 ZINC28949552 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50082 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(Cl)cc1 InChI=1S/C28H27ClN2O4S/c1-28(2,3)35-27(32)31-25-7-5-4-6-19(25)17-26(31)20-9-8-18-15-23(16-21(18)14-20)30-36(33,34)24-12-10-22(29)11-13-24/h4-14,17,23,30H,15-16H2,1-3H3 KEXOTJQYORSDJN-UHFFFAOYSA-N 27306 indole derivative, 5a::tert-butyl 2-{2-[(4-chlorobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1160 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27306&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190846 57299015 ZINC28949556 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50083 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H27FN2O4S/c1-28(2,3)35-27(32)31-25-7-5-4-6-19(25)17-26(31)20-9-8-18-15-23(16-21(18)14-20)30-36(33,34)24-12-10-22(29)11-13-24/h4-14,17,23,30H,15-16H2,1-3H3 XXFZWQNDUDEIOH-UHFFFAOYSA-N 27307 indole derivative, 5b::tert-butyl 2-{2-[(4-fluorobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 460 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27307&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190847 57299016 ZINC28949560 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50084 CCc1ccc(cc1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C30H32N2O4S/c1-5-20-10-14-26(15-11-20)37(34,35)31-25-17-21-12-13-23(16-24(21)18-25)28-19-22-8-6-7-9-27(22)32(28)29(33)36-30(2,3)4/h6-16,19,25,31H,5,17-18H2,1-4H3 ILNYYRYYUAWVSN-UHFFFAOYSA-N 27308 indole derivative, 5c::tert-butyl 2-{2-[(4-ethylbenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 650 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27308&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190848 57299017 ZINC28949564 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50085 Cc1ccc(cc1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C29H30N2O4S/c1-19-9-13-25(14-10-19)36(33,34)30-24-16-20-11-12-22(15-23(20)17-24)27-18-21-7-5-6-8-26(21)31(27)28(32)35-29(2,3)4/h5-15,18,24,30H,16-17H2,1-4H3 SSQVZKYSPZQBIV-UHFFFAOYSA-N 27309 indole derivative, 5d::tert-butyl 2-{2-[(4-methylbenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 430 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27309&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190849 57299018 ZINC28949569 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50086 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(cc1)C(F)(F)F InChI=1S/C29H27F3N2O4S/c1-28(2,3)38-27(35)34-25-7-5-4-6-19(25)17-26(34)20-9-8-18-15-23(16-21(18)14-20)33-39(36,37)24-12-10-22(11-13-24)29(30,31)32/h4-14,17,23,33H,15-16H2,1-3H3 IEFIRZRIIIGNIE-UHFFFAOYSA-N 27310 indole derivative, 5e::tert-butyl 2-(2-{[4-(trifluoromethyl)benzene]sulfonamido}-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 730 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27310&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190850 57299019 ZINC28949574 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50087 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccc(Cl)c1 InChI=1S/C28H27ClN2O4S/c1-28(2,3)35-27(32)31-25-10-5-4-7-19(25)16-26(31)20-12-11-18-14-23(15-21(18)13-20)30-36(33,34)24-9-6-8-22(29)17-24/h4-13,16-17,23,30H,14-15H2,1-3H3 KNAFZUYKGSZIFR-UHFFFAOYSA-N 27311 indole derivative, 5f::tert-butyl 2-{2-[(3-chlorobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1810 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27311&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190851 57299020 ZINC28949578 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50088 Cc1cccc(c1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C29H30N2O4S/c1-19-8-7-10-25(14-19)36(33,34)30-24-16-20-12-13-22(15-23(20)17-24)27-18-21-9-5-6-11-26(21)31(27)28(32)35-29(2,3)4/h5-15,18,24,30H,16-17H2,1-4H3 RUUQQFYQVWJFKU-UHFFFAOYSA-N 27312 indole derivative, 5g::tert-butyl 2-{2-[(3-methylbenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1330 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27312&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190852 57299021 ZINC28949584 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50089 COc1cccc(c1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-26-11-6-5-8-20(26)17-27(31)21-13-12-19-15-23(16-22(19)14-21)30-37(33,34)25-10-7-9-24(18-25)35-4/h5-14,17-18,23,30H,15-16H2,1-4H3 CDXKPTNMOFCZKM-UHFFFAOYSA-N 27313 indole derivative, 5h::tert-butyl 2-{2-[(3-methoxybenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 960 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27313&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190853 57299022 ZINC28949588 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50090 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccc(c1)C#N InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-26-10-5-4-8-21(26)17-27(32)22-12-11-20-15-24(16-23(20)14-22)31-37(34,35)25-9-6-7-19(13-25)18-30/h4-14,17,24,31H,15-16H2,1-3H3 BHWGWWTXKOFQPA-UHFFFAOYSA-N 27314 indole derivative, 5i::tert-butyl 2-{2-[(3-cyanobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 460 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27314&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190854 57299023 ZINC28949592 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50091 COC(=O)c1ccccc1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C30H30N2O6S/c1-30(2,3)38-29(34)32-25-11-7-5-9-20(25)18-26(32)21-14-13-19-16-23(17-22(19)15-21)31-39(35,36)27-12-8-6-10-24(27)28(33)37-4/h5-15,18,23,31H,16-17H2,1-4H3 KPFCKXIWPWIOAM-UHFFFAOYSA-N 27315 indole derivative, 5j::tert-butyl 2-(2-{[2-(methoxycarbonyl)benzene]sulfonamido}-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 600 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27315&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190855 57299024 ZINC28949596 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C(O)=O InChI=1S/C29H28N2O6S/c1-29(2,3)37-28(34)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-38(35,36)26-11-7-5-9-23(26)27(32)33/h4-14,17,22,30H,15-16H2,1-3H3,(H,32,33) GAIAHCFLZIBWBP-UHFFFAOYSA-N 27316 2-[(5-{1-[(tert-butoxy)carbonyl]-1H-indol-2-yl}-2,3-dihydro-1H-inden-2-yl)sulfamoyl]benzoic acid::indole derivative, 5k Oxysterols receptor LXR-beta 3350 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27316&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190856 57299025 ZINC28949600 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50093 Cc1ccccc1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C29H30N2O4S/c1-19-9-5-8-12-27(19)36(33,34)30-24-16-20-13-14-22(15-23(20)17-24)26-18-21-10-6-7-11-25(21)31(26)28(32)35-29(2,3)4/h5-15,18,24,30H,16-17H2,1-4H3 KZSQWSOCBOKLFN-UHFFFAOYSA-N 27317 indole derivative, 5l::tert-butyl 2-{2-[(2-methylbenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 200 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27317&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190857 57299026 ZINC28949605 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50094 COc1ccccc1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-24-10-6-5-9-20(24)18-25(31)21-14-13-19-16-23(17-22(19)15-21)30-37(33,34)27-12-8-7-11-26(27)35-4/h5-15,18,23,30H,16-17H2,1-4H3 RJIVSRDFLIRYNZ-UHFFFAOYSA-N 27318 indole derivative, 5m::tert-butyl 2-{2-[(2-methoxybenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 600 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27318&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190858 57299027 ZINC28949609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50095 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C(F)(F)F InChI=1S/C29H27F3N2O4S/c1-28(2,3)38-27(35)34-24-10-6-4-8-19(24)17-25(34)20-13-12-18-15-22(16-21(18)14-20)33-39(36,37)26-11-7-5-9-23(26)29(30,31)32/h4-14,17,22,33H,15-16H2,1-3H3 MZOJZGMOVWKVAE-UHFFFAOYSA-N 27319 indole derivative, 5n::tert-butyl 2-(2-{[2-(trifluoromethyl)benzene]sulfonamido}-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 800 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27319&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190859 57299028 ZINC28949613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50096 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C#N InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-25-10-6-4-8-20(25)17-26(32)21-13-12-19-15-24(16-23(19)14-21)31-37(34,35)27-11-7-5-9-22(27)18-30/h4-14,17,24,31H,15-16H2,1-3H3 GWRYATMHUPAHEK-UHFFFAOYSA-N 27320 indole derivative, 5o::tert-butyl 2-{2-[(2-cyanobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 60 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27320&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17753624 57299029 ZINC28949617 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50097 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1F InChI=1S/C28H27FN2O4S/c1-28(2,3)35-27(32)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-36(33,34)26-11-7-5-9-23(26)29/h4-14,17,22,30H,15-16H2,1-3H3 LYZPFOMSSIJUAS-UHFFFAOYSA-N 27321 indole derivative, 5p::tert-butyl 2-{2-[(2-fluorobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 100 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27321&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190860 57299030 ZINC28949621 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50098 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1c(F)cccc1F InChI=1S/C28H26F2N2O4S/c1-28(2,3)36-27(33)32-24-10-5-4-7-18(24)16-25(32)19-12-11-17-14-21(15-20(17)13-19)31-37(34,35)26-22(29)8-6-9-23(26)30/h4-13,16,21,31H,14-15H2,1-3H3 HQASURSDDJNDLH-UHFFFAOYSA-N 27322 indole derivative, 5q::tert-butyl 2-{2-[(2,6-difluorobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 90 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27322&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190861 57299031 ZINC28949625 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50099 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1Cl InChI=1S/C28H27ClN2O4S/c1-28(2,3)35-27(32)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-36(33,34)26-11-7-5-9-23(26)29/h4-14,17,22,30H,15-16H2,1-3H3 XUXWBFCBXZAZME-UHFFFAOYSA-N 27323 indole derivative, 5r::tert-butyl 2-{2-[(2-chlorobenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 760 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27323&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190862 57299032 ZINC28949629 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50100 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccs1 InChI=1S/C26H26N2O4S2/c1-26(2,3)32-25(29)28-22-8-5-4-7-18(22)16-23(28)19-11-10-17-14-21(15-20(17)13-19)27-34(30,31)24-9-6-12-33-24/h4-13,16,21,27H,14-15H2,1-3H3 AGKUZMNQBHXLGU-UHFFFAOYSA-N 27324 indole derivative, 5s::tert-butyl 2-[2-(thiophene-2-sulfonamido)-2,3-dihydro-1H-inden-5-yl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 110 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27324&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190863 57299033 ZINC28949633 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50101 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(s1)-c1ccon1 InChI=1S/C29H27N3O5S2/c1-29(2,3)37-28(33)32-24-7-5-4-6-19(24)17-25(32)20-9-8-18-15-22(16-21(18)14-20)31-39(34,35)27-11-10-26(38-27)23-12-13-36-30-23/h4-14,17,22,31H,15-16H2,1-3H3 AOVLEUVYXSWIDO-UHFFFAOYSA-N 27325 indole derivative, 5t::tert-butyl 2-(2-{[5-(1,2-oxazol-3-yl)thiophene-2-]sulfonamido}-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 670 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27325&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190864 57299034 ZINC28949638 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50102 Cc1noc(C)c1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C27H29N3O5S/c1-16-25(17(2)35-28-16)36(32,33)29-22-13-18-10-11-20(12-21(18)14-22)24-15-19-8-6-7-9-23(19)30(24)26(31)34-27(3,4)5/h6-12,15,22,29H,13-14H2,1-5H3 RXIFCVQKTVDIHV-UHFFFAOYSA-N 27326 indole derivative, 5u::tert-butyl 2-{2-[(3,5-dimethyl-1,2-oxazole-4-)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 130 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27326&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190865 57299035 ZINC28949643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50103 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C34H32N2O4S/c1-34(2,3)40-33(37)36-31-12-8-7-11-26(31)22-32(36)27-14-13-25-20-29(21-28(25)19-27)35-41(38,39)30-17-15-24(16-18-30)23-9-5-4-6-10-23/h4-19,22,29,35H,20-21H2,1-3H3 OVYUZYMDQSIVKO-UHFFFAOYSA-N 27327 indole derivative, 5v::tert-butyl 2-{2-[(4-phenylbenzene)sulfonamido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 2100 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27327&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190866 57299036 ZINC28949647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50104 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)Cc1ccccc1 InChI=1S/C29H30N2O4S/c1-29(2,3)35-28(32)31-26-12-8-7-11-22(26)18-27(31)23-14-13-21-16-25(17-24(21)15-23)30-36(33,34)19-20-9-5-4-6-10-20/h4-15,18,25,30H,16-17,19H2,1-3H3 HUXLUFBSEKYKGP-UHFFFAOYSA-N 27328 indole derivative, 5w::tert-butyl 2-[2-(phenylmethanesulfonamido)-2,3-dihydro-1H-inden-5-yl]-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 520 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27328&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190867 57299037 ZINC28949651 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50105 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(C)(=O)=O InChI=1S/C23H26N2O4S/c1-23(2,3)29-22(26)25-20-8-6-5-7-16(20)14-21(25)17-10-9-15-12-19(13-18(15)11-17)24-30(4,27)28/h5-11,14,19,24H,12-13H2,1-4H3 VTYPSCYHJXORCD-UHFFFAOYSA-N 27329 indole derivative, 5x::tert-butyl 2-(2-methanesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 210 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27329&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190868 57299038 ZINC28949655 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50106 CCS(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C24H28N2O4S/c1-5-31(28,29)25-20-13-16-10-11-18(12-19(16)14-20)22-15-17-8-6-7-9-21(17)26(22)23(27)30-24(2,3)4/h6-12,15,20,25H,5,13-14H2,1-4H3 GUQBISCYWXXXQL-UHFFFAOYSA-N 27330 indole derivative, 5y::tert-butyl 2-(2-ethanesulfonamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 400 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27330&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190869 57299039 ZINC28949658 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50112 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)c1ccccc1 InChI=1S/C29H28N2O3/c1-29(2,3)34-28(33)31-25-12-8-7-11-21(25)18-26(31)22-14-13-20-16-24(17-23(20)15-22)30-27(32)19-9-5-4-6-10-19/h4-15,18,24H,16-17H2,1-3H3,(H,30,32) YHKUJDFJHRPTPX-UHFFFAOYSA-N 27331 indole derivative, 37::tert-butyl 2-(2-benzamido-2,3-dihydro-1H-inden-5-yl)-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 190 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27331&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190870 57299040 ZINC28949662 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50113 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)c1ccccc1F InChI=1S/C29H27FN2O3/c1-29(2,3)35-28(34)32-25-11-7-4-8-19(25)17-26(32)20-13-12-18-15-22(16-21(18)14-20)31-27(33)23-9-5-6-10-24(23)30/h4-14,17,22H,15-16H2,1-3H3,(H,31,33) QKNPSJWHUYDMPZ-UHFFFAOYSA-N 27332 indole derivative, 38::tert-butyl 2-{2-[(2-fluorobenzene)amido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 170 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27332&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190871 57299041 ZINC28949666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50114 COc1ccccc1C(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C InChI=1S/C30H30N2O4/c1-30(2,3)36-29(34)32-25-11-7-5-9-20(25)18-26(32)21-14-13-19-16-23(17-22(19)15-21)31-28(33)24-10-6-8-12-27(24)35-4/h5-15,18,23H,16-17H2,1-4H3,(H,31,33) RBJGBZDZNUUOPX-UHFFFAOYSA-N 27333 indole derivative, 39::tert-butyl 2-{2-[(2-methoxybenzene)amido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 470 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190872 57299042 ZINC28949670 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50115 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)c1ccccc1O InChI=1S/C29H28N2O4/c1-29(2,3)35-28(34)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-27(33)23-9-5-7-11-26(23)32/h4-14,17,22,32H,15-16H2,1-3H3,(H,30,33) RMDWQZDXZBKQAU-UHFFFAOYSA-N 27334 indole derivative, 40::tert-butyl 2-{2-[(2-hydroxybenzene)amido]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 530 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27334&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190873 57299043 ZINC28949674 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50116 CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)Nc1ccccc1 InChI=1S/C29H29N3O3/c1-29(2,3)35-28(34)32-25-12-8-7-9-20(25)18-26(32)21-14-13-19-16-24(17-22(19)15-21)31-27(33)30-23-10-5-4-6-11-23/h4-15,18,24H,16-17H2,1-3H3,(H2,30,31,33) VWKOKWYNWNUAPJ-UHFFFAOYSA-N 27335 indole derivative, 41::tert-butyl 2-{2-[(phenylcarbamoyl)amino]-2,3-dihydro-1H-inden-5-yl}-1H-indole-1-carboxylate Oxysterols receptor LXR-beta 1500 Curated from the literature by BindingDB 10.1016/j.bmcl.2007.03.076 10.7270/Q2HD7T00 17416521 aid1798795 Bakir, F; Kher, S; Pannala, M; Wilson, N; Nguyen, T; Sircar, I; Takedomi, K; Fukushima, C; Zapf, J; Xu, K; Zhang, SH; Liu, J; Morera, L; Schneider, L; Sakurai, N; Jack, R; Cheng, JF Tanabe Research Laboratories USA, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27335&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25190874 57299044 ZINC28949679 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51318 COC(=O)[C@](C)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C21H20ClNO4S/c1-21(20(24)27-2,28(25,26)15-6-4-3-5-7-15)13-10-16-17-12-14(22)8-9-18(17)23-19(16)11-13/h3-9,12-13,23H,10-11H2,1-2H3/t13-,21+/m1/s1 ATLBWTISZKGUSO-ASSNKEHSSA-N 28131 methyl (2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]propanoate::tetrahydro-cyclopenta[b]indole, (+/-)8 Oxysterols receptor LXR-beta 350 250 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28131&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218828 57560643 ZINC40863098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51319 COC(=O)[C@](C)([C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C22H21ClFNO4S/c1-22(21(26)29-2,30(27,28)16-7-5-15(24)6-8-16)13-3-9-17-18-12-14(23)4-10-19(18)25-20(17)11-13/h4-8,10,12-13,25H,3,9,11H2,1-2H3/t13-,22+/m1/s1 BUJFSGHBPYJFOP-DMZKTXOQSA-N 28132 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(4-fluorobenzene)sulfonyl]propanoate::tetrahydro-carbazole, (+/-)12 Oxysterols receptor LXR-beta 3300 370 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28132&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218829 57560644 ZINC36426383 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51320 COC(=O)[C@](C)([C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21)S(=O)(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C22H20Cl3NO4S/c1-22(21(27)30-2,31(28,29)14-5-7-17(24)18(25)11-14)12-3-6-15-16-10-13(23)4-8-19(16)26-20(15)9-12/h4-5,7-8,10-12,26H,3,6,9H2,1-2H3/t12-,22+/m1/s1 WUCULNIWKNLKMF-IPQOISQHSA-N 28133 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(3,4-dichlorobenzene)sulfonyl]propanoate::tetrahydro-carbazole, (+/-)13 Oxysterols receptor LXR-beta 31200 >40000 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28133&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218830 57560645 ZINC40848539 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51321 COC(=O)[C@](C)([C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21)S(=O)(=O)c1cccc(Cl)c1 InChI=1S/C22H21Cl2NO4S/c1-22(21(26)29-2,30(27,28)16-5-3-4-14(23)11-16)13-6-8-17-18-12-15(24)7-9-19(18)25-20(17)10-13/h3-5,7,9,11-13,25H,6,8,10H2,1-2H3/t13-,22+/m1/s1 YJSNRRWHVBEGIG-DMZKTXOQSA-N 28134 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(3-chlorobenzene)sulfonyl]propanoate::tetrahydro-carbazole, (+/-)14 Oxysterols receptor LXR-beta 150 1700 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28134&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218831 57560646 ZINC40848541 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51322 COC(=O)[C@](C)([C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21)S(=O)(=O)c1ccccc1Cl InChI=1S/C22H21Cl2NO4S/c1-22(21(26)29-2,30(27,28)20-6-4-3-5-17(20)24)13-7-9-15-16-12-14(23)8-10-18(16)25-19(15)11-13/h3-6,8,10,12-13,25H,7,9,11H2,1-2H3/t13-,22+/m1/s1 GVGFPQNEINNGIL-DMZKTXOQSA-N 28135 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(2-chlorobenzene)sulfonyl]propanoate::tetrahydro-carbazole, (+/-)15 Oxysterols receptor LXR-beta 800 1530 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28135&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218832 57560647 ZINC40380501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51323 COC(=O)[C@](C)([C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21)S(=O)(=O)c1ccccc1OC InChI=1S/C23H24ClNO5S/c1-23(22(26)30-3,31(27,28)21-7-5-4-6-20(21)29-2)14-8-10-16-17-13-15(24)9-11-18(17)25-19(16)12-14/h4-7,9,11,13-14,25H,8,10,12H2,1-3H3/t14-,23+/m1/s1 GYQVWNOSYMGCOY-FATZIPQQSA-N 28136 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(2-methoxybenzene)sulfonyl]propanoate::tetrahydro-carbazole, (+/-)16 Oxysterols receptor LXR-beta 3420 3160 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28136&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218833 57560648 ZINC36426682 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51324 COC(=O)[C@](F)([C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21)S(=O)(=O)c1cccc(Cl)c1 InChI=1S/C21H18Cl2FNO4S/c1-29-20(26)21(24,30(27,28)15-4-2-3-13(22)10-15)12-5-7-16-17-11-14(23)6-8-18(17)25-19(16)9-12/h2-4,6,8,10-12,25H,5,7,9H2,1H3/t12-,21+/m1/s1 KPQLWJWAGXJIST-GTJPDFRWSA-N 28137 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(3-chlorobenzene)sulfonyl]-2-fluoroacetate::tetrahydro-carbazole, (+/-)17 Oxysterols receptor LXR-beta 31 1810 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28137&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218834 57560649 ZINC40876091 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51325 COC(=O)[C@](F)([C@@H]1CCc2c(C1)[nH]c1ccc(Cl)cc21)S(=O)(=O)c1cccc(F)c1 InChI=1S/C21H18ClF2NO4S/c1-29-20(26)21(24,30(27,28)15-4-2-3-14(23)11-15)12-5-7-16-17-10-13(22)6-8-18(17)25-19(16)9-12/h2-4,6,8,10-12,25H,5,7,9H2,1H3/t12-,21+/m1/s1 TUWUXPOHUVIUKC-GTJPDFRWSA-N 28138 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-fluoro-2-[(3-fluorobenzene)sulfonyl]acetate::tetrahydro-carbazole, (+/-)18 Oxysterols receptor LXR-beta 21 430 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28138&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218835 57560650 ZINC40861441 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51326 COC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1cccc(OC)c1 InChI=1S/C21H19ClFNO5S/c1-28-14-4-3-5-15(11-14)30(26,27)21(23,20(25)29-2)12-8-16-17-10-13(22)6-7-18(17)24-19(16)9-12/h3-7,10-12,24H,8-9H2,1-2H3/t12-,21+/m1/s1 MBYSDJHWBSSHJB-GTJPDFRWSA-N 28139 methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-fluoro-2-[(3-methoxybenzene)sulfonyl]acetate::tetrahydro-cyclopenta[b]indole, (+/-)19 Oxysterols receptor LXR-beta 56 160 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28139&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218836 57560651 ZINC40861761 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51327 COC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1cccc(Cl)c1 InChI=1S/C20H16Cl2FNO4S/c1-28-19(25)20(23,29(26,27)14-4-2-3-12(21)9-14)11-7-15-16-10-13(22)5-6-17(16)24-18(15)8-11/h2-6,9-11,24H,7-8H2,1H3/t11-,20+/m1/s1 MTRFPHKOVNDQRZ-GIPWTMENSA-N 28140 methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-[(3-chlorobenzene)sulfonyl]-2-fluoroacetate::tetrahydro-cyclopenta[b]indole, (+/-)20 Oxysterols receptor LXR-beta 700 190 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28140&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218837 57560652 ZINC40393376 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51328 COC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1cccc(F)c1 InChI=1S/C20H16ClF2NO4S/c1-28-19(25)20(23,29(26,27)14-4-2-3-13(22)10-14)11-7-15-16-9-12(21)5-6-17(16)24-18(15)8-11/h2-6,9-11,24H,7-8H2,1H3/t11-,20+/m1/s1 XFCBZLRZOYZTSH-GIPWTMENSA-N 28141 methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-fluoro-2-[(3-fluorobenzene)sulfonyl]acetate::tetrahydro-cyclopenta[b]indole, (+/-)21 Oxysterols receptor LXR-beta 26 360 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28141&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218838 57560653 ZINC40848094 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51329 COC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1cccc(Br)c1 InChI=1S/C20H16BrClFNO4S/c1-28-19(25)20(23,29(26,27)14-4-2-3-12(21)9-14)11-7-15-16-10-13(22)5-6-17(16)24-18(15)8-11/h2-6,9-11,24H,7-8H2,1H3/t11-,20+/m1/s1 HTTQXFNNULAJHM-GIPWTMENSA-N 28142 methyl (2S)-2-[(3-bromobenzene)sulfonyl]-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-fluoroacetate::tetrahydro-cyclopenta[b]indole, (+/-)22 Oxysterols receptor LXR-beta 30 150 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28142&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218839 57560654 ZINC40848226 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51330 COC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1cccnc1 InChI=1S/C19H16ClFN2O4S/c1-27-18(24)19(21,28(25,26)13-3-2-6-22-10-13)11-7-14-15-9-12(20)4-5-16(15)23-17(14)8-11/h2-6,9-11,23H,7-8H2,1H3/t11-,19+/m1/s1 WWRWMFVFGCQTFC-WYRIXSBYSA-N 28143 methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-fluoro-2-(pyridine-3-sulfonyl)acetate::tetrahydro-cyclopenta[b]indole, (+/-)23 Oxysterols receptor LXR-beta 500 340 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28143&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218840 57560655 ZINC38309209 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51331 COC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccn1 InChI=1S/C19H16ClFN2O4S/c1-27-18(24)19(21,28(25,26)17-4-2-3-7-22-17)11-8-13-14-10-12(20)5-6-15(14)23-16(13)9-11/h2-7,10-11,23H,8-9H2,1H3/t11-,19+/m1/s1 TWQMTZMVDLJNNX-WYRIXSBYSA-N 28144 methyl (2S)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-fluoro-2-(pyridine-2-sulfonyl)acetate::tetrahydro-cyclopenta[b]indole, (+/-)24 Oxysterols receptor LXR-beta 3950 270 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28144&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218841 57560656 ZINC38309205 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51332 COC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)nc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C19H16ClFN2O4S/c1-27-18(24)19(21,28(25,26)12-5-3-2-4-6-12)11-9-13-15(10-11)22-14-7-8-16(20)23-17(13)14/h2-8,11,22H,9-10H2,1H3/t11-,19+/m1/s1 QUJZEJMHCCGRNR-WYRIXSBYSA-N 28145 methyl (2S)-2-(benzenesulfonyl)-2-[(4R)-11-chloro-7,12-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9,11-tetraen-4-yl]-2-fluoroacetate::tetrahydro-cyclopenta[b]indole, (+/-)25 Oxysterols receptor LXR-beta 400 370 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28145&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218842 57560657 ZINC40380683 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51333 CNC(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C20H18ClFN2O3S/c1-23-19(25)20(22,28(26,27)14-5-3-2-4-6-14)12-9-15-16-11-13(21)7-8-17(16)24-18(15)10-12/h2-8,11-12,24H,9-10H2,1H3,(H,23,25)/t12-,20+/m1/s1 OESYIXZKTVZBJV-ODXCJYRJSA-N 28146 (2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-fluoro-N-methylacetamide::tetrahydro-cyclopenta[b]indole, (+/-)26a Oxysterols receptor LXR-beta 3870 400 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28146&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218843 57560658 ZINC40848333 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51334 CN(C)C(=O)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C21H20ClFN2O3S/c1-25(2)20(26)21(23,29(27,28)15-6-4-3-5-7-15)13-10-16-17-12-14(22)8-9-18(17)24-19(16)11-13/h3-9,12-13,24H,10-11H2,1-2H3/t13-,21+/m1/s1 ULNCPHZNOMRNFX-ASSNKEHSSA-N 28147 (2S)-2-(benzenesulfonyl)-2-[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]-2-fluoro-N,N-dimethylacetamide::tetrahydro-cyclopenta[b]indole, (+/-)26b Oxysterols receptor LXR-beta 170 110 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28147&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218844 57560659 ZINC40848547 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51335 F[C@]([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)(c1nnco1)S(=O)(=O)c1ccccc1 InChI=1S/C20H15ClFN3O3S/c21-13-6-7-17-16(10-13)15-8-12(9-18(15)24-17)20(22,19-25-23-11-28-19)29(26,27)14-4-2-1-3-5-14/h1-7,10-12,24H,8-9H2/t12-,20+/m1/s1 OUYZAPGHALHUNN-ODXCJYRJSA-N 28148 2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]fluoromethyl]-1,3,4-oxadiazole::tetrahydro-cyclopenta[b]indole, (+/-)27a Oxysterols receptor LXR-beta 490 170 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28148&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218845 57560660 ZINC40848878 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51336 Cc1nnc(o1)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C21H17ClFN3O3S/c1-12-25-26-20(29-12)21(23,30(27,28)15-5-3-2-4-6-15)13-9-16-17-11-14(22)7-8-18(17)24-19(16)10-13/h2-8,11,13,24H,9-10H2,1H3/t13-,21+/m1/s1 QGRVHWHTSMJVAO-ASSNKEHSSA-N 28149 2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]fluoromethyl]-5-methyl-1,3,4-oxadiazole::tetrahydro-cyclopenta[b]indole, (+/-)27b Oxysterols receptor LXR-beta 65 240 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28149&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218846 57560661 ZINC34480353 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51337 F[C@]([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)(c1nnc(o1)C1CC1)S(=O)(=O)c1ccccc1 InChI=1S/C23H19ClFN3O3S/c24-15-8-9-19-18(12-15)17-10-14(11-20(17)26-19)23(25,22-28-27-21(31-22)13-6-7-13)32(29,30)16-4-2-1-3-5-16/h1-5,8-9,12-14,26H,6-7,10-11H2/t14-,23+/m1/s1 FDPTZOBGHHQMTN-FATZIPQQSA-N 28150 2-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]fluoromethyl]-5-cyclopropyl-1,3,4-oxadiazole::tetrahydro-cyclopenta[b]indole, (+/-)27c Oxysterols receptor LXR-beta 83 92 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28150&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218847 57560662 ZINC40863096 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51338 CN(C)c1nnc(o1)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C22H20ClFN4O3S/c1-28(2)21-27-26-20(31-21)22(24,32(29,30)15-6-4-3-5-7-15)13-10-16-17-12-14(23)8-9-18(17)25-19(16)11-13/h3-9,12-13,25H,10-11H2,1-2H3/t13-,22+/m1/s1 IPFQNBHHJCPINI-DMZKTXOQSA-N 28151 5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]fluoromethyl]-N,N-dimethyl-1,3,4-oxadiazol-2-amine::tetrahydro-cyclopenta[b]indole, (+/-)27d Oxysterols receptor LXR-beta 150 76 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28151&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218848 57560663 ZINC40391658 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51339 Cc1noc(n1)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C21H17ClFN3O3S/c1-12-24-20(29-26-12)21(23,30(27,28)15-5-3-2-4-6-15)13-9-16-17-11-14(22)7-8-18(17)25-19(16)10-13/h2-8,11,13,25H,9-10H2,1H3/t13-,21+/m1/s1 QZUURSVVTAUZTJ-ASSNKEHSSA-N 28152 5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]fluoromethyl]-3-methyl-1,2,4-oxadiazole::tetrahydro-cyclopenta[b]indole, (+/-)28a Oxysterols receptor LXR-beta 27 210 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28152&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218849 57560664 ZINC40866595 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51340 CN(C)c1noc(n1)[C@](F)([C@H]1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccc1 InChI=1S/C22H20ClFN4O3S/c1-28(2)21-26-20(31-27-21)22(24,32(29,30)15-6-4-3-5-7-15)13-10-16-17-12-14(23)8-9-18(17)25-19(16)11-13/h3-9,12-13,25H,10-11H2,1-2H3/t13-,22+/m1/s1 LIBSEWDVSYHTJA-DMZKTXOQSA-N 28154 5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]fluoromethyl]-N,N-dimethyl-1,2,4-oxadiazol-3-amine::tetrahydro-cyclopenta[b]indole, (+/-)28c Oxysterols receptor LXR-beta 13 120 Curated from the literature by BindingDB 10.1016/j.bmcl.2009.01.109 10.7270/Q2BK19PN 19231176 aid1798871 Ratni, H; Blum-Kaelin, D; Dehmlow, H; Hartman, P; Jablonski, P; Masciadri, R; Maugeais, C; Patiny-Adam, A; Panday, N; Wright, M F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=28154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=28154&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25218851 57560666 ZINC40845228 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 186706 CC(C)(O)C1OC2CCC3(C)C4(C)C(Cc5c4[nH]c4ccccc54)CCC3(O)C2=CC1=O InChI=1S/C27H33NO4/c1-24(2,30)23-20(29)14-18-21(32-23)10-11-25(3)26(4)15(9-12-27(18,25)31)13-17-16-7-5-6-8-19(16)28-22(17)26/h5-8,14-15,21,23,28,30-31H,9-13H2,1-4H3 ACNHBCIZLNNLRS-UHFFFAOYSA-N 86263 CAS_57186-25-1::NSC_0::paxilline Oxysterols receptor LXR-beta 1100 PDSP Ki 10.1124/jpet.103.052852 10.7270/Q2JD4VCH 12893846 Bramlett, KS; Houck, KA; Borchert, KM; Dowless, MS; Kulanthaivel, P; Zhang, Y; Beyer, TP; Schmidt, R; Thomas, JS; Michael, LF; Barr, R; Montrose, C; Eacho, PI; Cao, G; Burris, TP Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86263&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4697 136352363 2309 ZINC03874620 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 186707 CC(C)CC[C@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25-,26-,27+/m0/s1 RZPAXNJLEKLXNO-QUOSNDFLSA-N 20176 (1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::22(R)-hydroxycholesterol::22(S)-hydroxycholesterol Oxysterols receptor LXR-beta 490 PDSP Ki 10.1124/jpet.103.052852 10.7270/Q2JD4VCH 12893846 Bramlett, KS; Houck, KA; Borchert, KM; Dowless, MS; Kulanthaivel, P; Zhang, Y; Beyer, TP; Schmidt, R; Thomas, JS; Michael, LF; Barr, R; Montrose, C; Eacho, PI; Cao, G; Burris, TP Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20176&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168038 49688251 1301 ZINC05759161 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238595 Cc1sc(NC(=O)c2ccc(Cl)s2)c(C(N)=O)c1C InChI=1S/C12H11ClN2O2S2/c1-5-6(2)18-12(9(5)10(14)16)15-11(17)7-3-4-8(13)19-7/h3-4H,1-2H3,(H2,14,16)(H,15,17) BFCDSWDRSWYOSX-UHFFFAOYSA-N 49303 2-[(5-chloranylthiophen-2-yl)carbonylamino]-4,5-dimethyl-thiophene-3-carboxamide::2-[(5-chlorothiophene-2-carbonyl)amino]-4,5-dimethyl-thiophene-3-carboxamide::2-[(5-chlorothiophene-2-carbonyl)amino]-4,5-dimethylthiophene-3-carboxamide::2-[[(5-chloro-2-thiophenyl)-oxomethyl]amino]-4,5-dimethyl-3-thiophenecarboxamide::MLS000065679::N-[3-(aminocarbonyl)-4,5-dimethyl-2-thienyl]-5-chloro-2-thiophenecarboxamide::SMR000080332::cid_1245304 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49303&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1245304 252629583 ZINC01053686 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238596 COc1ccc(cc1)-c1noc(n1)-c1ccccc1F InChI=1S/C15H11FN2O2/c1-19-11-8-6-10(7-9-11)14-17-15(20-18-14)12-4-2-3-5-13(12)16/h2-9H,1H3 DANKTKKLNXAGKW-UHFFFAOYSA-N 50293103 5-(2-fluorophenyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole::CHEMBL472929::cid_925735 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50293103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50293103&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 925735 104134654 CHEMBL472929 ZINC00515041 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238597 COc1ccccc1-c1nc(no1)-c1ccccn1 InChI=1S/C14H11N3O2/c1-18-12-8-3-2-6-10(12)14-16-13(17-19-14)11-7-4-5-9-15-11/h2-9H,1H3 JCQQRWFKXLYVTR-UHFFFAOYSA-N 50293102 5-(2-methoxyphenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole::CHEMBL512749::cid_912656 Oxysterols receptor LXR-beta 67539 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50293102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50293102&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 912656 104134653 CHEMBL512749 ZINC00496804 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238598 COc1cccc(c1)-c1nc2cc(C)ccc2o1 InChI=1S/C15H13NO2/c1-10-6-7-14-13(8-10)16-15(18-14)11-4-3-5-12(9-11)17-2/h3-9H,1-2H3 GEZFTJBSAPYQBR-UHFFFAOYSA-N 48172 2-(3-methoxyphenyl)-5-methyl-1,3-benzoxazole::MLS000110524::SMR000106453::cid_880161 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48172&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 880161 252628470 ZINC00450460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238599 Cc1ccc(cc1)-c1noc(n1)-c1cccs1 InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)12-14-13(16-15-12)11-3-2-8-17-11/h2-8H,1H3 ZBIZYSIIJRBDSE-UHFFFAOYSA-N 50171428 5-Thiophen-2-yl-3-p-tolyl-[1,2,4]oxadiazole::CHEMBL191015::cid_784811 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171428&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 784811 104057665 CHEMBL191015 ZINC00280924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238600 O=C1C(=CNCc2ccco2)C(=O)c2ccccc12 InChI=1S/C15H11NO3/c17-14-11-5-1-2-6-12(11)15(18)13(14)9-16-8-10-4-3-7-19-10/h1-7,9,16H,8H2 HXOPTYZHTQUBET-UHFFFAOYSA-N 114720 2-[(2-furanylmethylamino)methylidene]indene-1,3-dione::2-[(2-furfurylamino)methylene]indane-1,3-quinone::2-[(furan-2-ylmethylamino)methylidene]indene-1,3-dione::MLS000108102::SMR000104064::cid_869136 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114720&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 869136 252664201 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238601 Brc1ccc(o1)-c1nc(no1)-c1ccccn1 InChI=1S/C11H6BrN3O2/c12-9-5-4-8(16-9)11-14-10(15-17-11)7-3-1-2-6-13-7/h1-6H MWRCJQDUIXMGTI-UHFFFAOYSA-N 48183 5-(5-bromanylfuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole::5-(5-bromo-2-furanyl)-3-(2-pyridinyl)-1,2,4-oxadiazole::5-(5-bromo-2-furyl)-3-(2-pyridyl)-1,2,4-oxadiazole::5-(5-bromofuran-2-yl)-3-pyridin-2-yl-1,2,4-oxadiazole::MLS000114047::SMR000109937::cid_752709 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48183&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 752709 252628480 ZINC00204100 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238602 Cc1ccc(cc1)-c1nc2cc(C)ccc2o1 InChI=1S/C15H13NO/c1-10-3-6-12(7-4-10)15-16-13-9-11(2)5-8-14(13)17-15/h3-9H,1-2H3 RETREZSKHMFVCD-UHFFFAOYSA-N 48186 5-methyl-2-(4-methylphenyl)-1,3-benzoxazole::5-methyl-2-(p-tolyl)-1,3-benzoxazole::MLS000113249::SMR000109153::cid_85307 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48186&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 85307 252628483 ZINC00312745 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238603 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc1nccs1 InChI=1S/C13H12N4OS2/c1-6-5-7(2)16-12-8(6)9(14)10(20-12)11(18)17-13-15-3-4-19-13/h3-5H,14H2,1-2H3,(H,15,17,18) AYFVEDGCZPOUEK-UHFFFAOYSA-N 48192 3-amino-4,6-dimethyl-N-(1,3-thiazol-2-yl)thieno[2,3-b]pyridine-2-carboxamide::3-amino-4,6-dimethyl-N-(2-thiazolyl)-2-thieno[2,3-b]pyridinecarboxamide::3-amino-4,6-dimethyl-N-thiazol-2-yl-thieno[2,3-b]pyridine-2-carboxamide::3-azanyl-4,6-dimethyl-N-(1,3-thiazol-2-yl)thieno[2,3-b]pyridine-2-carboxamide::MLS000111537::SMR000107459::cid_788673 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48192&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 788673 252628489 ZINC00287840 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238604 Clc1ccc(NC(=O)COc2ccccc2Cl)nc1 InChI=1S/C13H10Cl2N2O2/c14-9-5-6-12(16-7-9)17-13(18)8-19-11-4-2-1-3-10(11)15/h1-7H,8H2,(H,16,17,18) MLWAGZDETKOBEW-UHFFFAOYSA-N 49344 2-(2-chloranylphenoxy)-N-(5-chloranylpyridin-2-yl)ethanamide::2-(2-chlorophenoxy)-N-(5-chloro-2-pyridinyl)acetamide::2-(2-chlorophenoxy)-N-(5-chloro-2-pyridyl)acetamide::2-(2-chlorophenoxy)-N-(5-chloropyridin-2-yl)acetamide::MLS000110802::SMR000106731::cid_883796 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49344&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 883796 252629623 ZINC00455387 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238605 COc1ccccc1Nc1nc(cs1)-c1cccs1 InChI=1S/C14H12N2OS2/c1-17-12-6-3-2-5-10(12)15-14-16-11(9-19-14)13-7-4-8-18-13/h2-9H,1H3,(H,15,16) ZXKZAXGRBLECJJ-UHFFFAOYSA-N 40934 (2-methoxyphenyl)-[4-(2-thienyl)thiazol-2-yl]amine::MLS000107274::N-(2-methoxyphenyl)-4-thiophen-2-yl-1,3-thiazol-2-amine::N-(2-methoxyphenyl)-4-thiophen-2-yl-2-thiazolamine::SMR000111646::cid_785027 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40934&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 785027 252621717 ZINC00281303 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238606 Cc1ccc(cc1)-c1noc(n1)-c1ccccc1Br InChI=1S/C15H11BrN2O/c1-10-6-8-11(9-7-10)14-17-15(19-18-14)12-4-2-3-5-13(12)16/h2-9H,1H3 IJJVPMHKKLHRRK-UHFFFAOYSA-N 49346 5-(2-bromophenyl)-3-(4-methylphenyl)-1,2,4-oxadiazole::5-(2-bromophenyl)-3-(p-tolyl)-1,2,4-oxadiazole::MLS000109501::SMR000105444::cid_867101 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49346&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 867101 252629625 ZINC00430485 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238607 Oc1cccc(c1)N=CCC(=O)c1ccccc1 InChI=1S/C15H13NO2/c17-14-8-4-7-13(11-14)16-10-9-15(18)12-5-2-1-3-6-12/h1-8,10-11,17H,9H2 NHZKHZWUYNAYCL-UHFFFAOYSA-N 48196 (E)-3-(3-hydroxyanilino)-1-phenyl-2-propen-1-one::(E)-3-(3-hydroxyanilino)-1-phenyl-prop-2-en-1-one::(E)-3-(3-hydroxyanilino)-1-phenylprop-2-en-1-one::(E)-3-[(3-hydroxyphenyl)amino]-1-phenyl-prop-2-en-1-one::MLS000107688::SMR000103653::cid_2255407 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48196&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 40624926 252628493 ZINC06552483 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238608 COc1ccc(cc1)-c1cn2ccc3ccccc3c2n1 InChI=1S/C18H14N2O/c1-21-15-8-6-14(7-9-15)17-12-20-11-10-13-4-2-3-5-16(13)18(20)19-17/h2-12H,1H3 ZYWYGWRRHDDHSN-UHFFFAOYSA-N 49357 2-(4-Methoxy-phenyl)-imidazo[2,1-a]isoquinoline::2-(4-methoxyphenyl)imidaz[2,1-a]isoquinoline::2-(4-methoxyphenyl)imidazo[2,1-a]isoquinoline::MLS000121240::SMR000118707::cid_746061 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49357&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 746061 252629636 ZINC00189092 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238609 O=C1C(C(=O)c2ccccc12)c1ccnc2ccccc12 InChI=1S/C18H11NO2/c20-17-13-6-1-2-7-14(13)18(21)16(17)12-9-10-19-15-8-4-3-5-11(12)15/h1-10,16H NLWBFTBOPUZRIV-UHFFFAOYSA-N 40551 2-(1H-quinolin-4-ylidene)indane-1,3-quinone::2-(1H-quinolin-4-ylidene)indene-1,3-dione::2-(4-quinolyl)indane-1,3-quinone::3-Hydroxy-2-quinolin-4-yl-inden-1-one::MLS000122777::SMR000120181::cid_5765327 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40551&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1207745 252621373 ZINC13124108 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238610 Oc1ccc2ccccc2c1CNc1cnc2ccccc2c1 InChI=1S/C20H16N2O/c23-20-10-9-14-5-1-3-7-17(14)18(20)13-21-16-11-15-6-2-4-8-19(15)22-12-16/h1-12,21,23H,13H2 LNVSFKTWZHFXGK-UHFFFAOYSA-N 51686 1-(Quinolin-3-ylaminomethyl)-naphthalen-2-ol::1-[(3-quinolinylamino)methyl]-2-naphthalenol::1-[(3-quinolylamino)methyl]-2-naphthol::1-[(quinolin-3-ylamino)methyl]naphthalen-2-ol::MLS000067462::SMR000124941::cid_951184 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51686&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 951184 252631867 ZINC00416793 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238611 Cc1ccc2ccc(nc2c1)C1C(=O)c2ccccc2C1=O InChI=1S/C19H13NO2/c1-11-6-7-12-8-9-15(20-16(12)10-11)17-18(21)13-4-2-3-5-14(13)19(17)22/h2-10,17H,1H3 HUNOPLLEKHNEKN-UHFFFAOYSA-N 40552 2-(7-Methyl-quinolin-2-yl)-indan-1,3-dione::2-(7-methyl-2-quinolinyl)indene-1,3-dione::2-(7-methyl-2-quinolyl)indane-1,3-quinone::2-(7-methylquinolin-2-yl)indene-1,3-dione::MLS000526211::SMR000116685::cid_2843949 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40552&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2843949 252621374 ZINC03833604 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238612 Cc1ccc(cc1)-n1nc2cc(C)c(N)cc2n1 InChI=1S/C14H14N4/c1-9-3-5-11(6-4-9)18-16-13-7-10(2)12(15)8-14(13)17-18/h3-8H,15H2,1-2H3 WPWFGODZYVRBTJ-UHFFFAOYSA-N 34668 6-Methyl-2-p-tolyl-2H-benzotriazol-5-ylamine::6-methyl-2-(4-methylphenyl)-5-benzotriazolamine::6-methyl-2-(4-methylphenyl)benzotriazol-5-amine::MLS000526849::SMR000117323::[6-methyl-2-(p-tolyl)benzotriazol-5-yl]amine::cid_736271 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34668&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 736271 252617318 ZINC00156786 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238613 Cc1cccc(Nc2nc(cs2)-c2cccs2)n1 InChI=1S/C13H11N3S2/c1-9-4-2-6-12(14-9)16-13-15-10(8-18-13)11-5-3-7-17-11/h2-8H,1H3,(H,14,15,16) GNUGUUFOOMYNGW-UHFFFAOYSA-N 49376 (6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2-yl)-amine::(6-methyl-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine::MLS000527802::N-(6-methyl-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine::N-(6-methylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::SMR000120376::cid_973018 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49376&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 973018 252629655 ZINC00613473 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238614 Cc1ccc2nc([nH]c2c1)-c1sc2nc(C)cc(C)c2c1N InChI=1S/C17H16N4S/c1-8-4-5-11-12(6-8)21-16(20-11)15-14(18)13-9(2)7-10(3)19-17(13)22-15/h4-7H,18H2,1-3H3,(H,20,21) LHXJRPUBIGMCAJ-UHFFFAOYSA-N 62936 4,6-dimethyl-2-(5-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-ylamine::4,6-dimethyl-2-(6-methyl-1H-benzimidazol-2-yl)-3-thieno[2,3-b]pyridinamine::4,6-dimethyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-amine::MLS000547126::SMR000115128::[4,6-dimethyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-yl]amine::cid_845804 Oxysterols receptor LXR-beta 67485 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=62936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=62936&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 845804 252642054 ZINC06493798 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238615 Cc1ccc2nc([nH]c2c1)-c1sc2nc(C)ccc2c1N InChI=1S/C16H14N4S/c1-8-3-6-11-12(7-8)20-15(19-11)14-13(17)10-5-4-9(2)18-16(10)21-14/h3-7H,17H2,1-2H3,(H,19,20) JSZUFXOHXIQNRZ-UHFFFAOYSA-N 49392 6-methyl-2-(5-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-ylamine::6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-3-thieno[2,3-b]pyridinamine::6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-amine::MLS000547128::SMR000115129::[6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-yl]amine::cid_845805 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49392&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 845805 252629671 ZINC06493799 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238616 Cc1ccc(cc1)-c1nc2-c3ccccc3Cn2n1 InChI=1S/C16H13N3/c1-11-6-8-12(9-7-11)15-17-16-14-5-3-2-4-13(14)10-19(16)18-15/h2-9H,10H2,1H3 QBPTUGPJJOOHAY-UHFFFAOYSA-N 48230 2-(4-methylphenyl)-5H-[1,2,4]triazolo[5,1-a]isoindole::2-(p-tolyl)-5H-[1,2,4]triazol[5,1-a]isoindole::MLS000548465::SMR000114054::cid_1040002 Oxysterols receptor LXR-beta 67496 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48230&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1040002 252628526 ZINC00711395 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238617 Clc1ccc(cc1)-c1nc2-c3ccccc3Cn2n1 InChI=1S/C15H10ClN3/c16-12-7-5-10(6-8-12)14-17-15-13-4-2-1-3-11(13)9-19(15)18-14/h1-8H,9H2 YOLSZCDGNJWZDU-UHFFFAOYSA-N 49393 2-(4-chlorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindole::2-(4-chlorophenyl)-5H-[1,2,4]triazolo[5,1-a]isoindole::MLS000548467::SMR000114053::cid_134450 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49393&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134450 252629672 ZINC01020522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238618 COc1ccccc1-c1nc(no1)-c1ccc(Br)o1 InChI=1S/C13H9BrN2O3/c1-17-9-5-3-2-4-8(9)13-15-12(16-19-13)10-6-7-11(14)18-10/h2-7H,1H3 QLLJJRSZQXRNKB-UHFFFAOYSA-N 49399 3-(5-bromanylfuran-2-yl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furanyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::MLS000522326::SMR000127594::cid_717857 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49399&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 717857 252629678 ZINC00116771 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238619 Brc1ccc(cc1)-n1ncc2ccccc2c1=O InChI=1S/C14H9BrN2O/c15-11-5-7-12(8-6-11)17-14(18)13-4-2-1-3-10(13)9-16-17/h1-9H PSGHMUSVWHDVRN-UHFFFAOYSA-N 49407 2-(4-bromophenyl)-1(2H)-phthalazinone::2-(4-bromophenyl)-1-phthalazinone::2-(4-bromophenyl)phthalazin-1-one::MLS000540544::SMR000125802::cid_1478661 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49407&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1478661 252629686 ZINC01391337 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238620 Clc1ccc(cc1)-n1ncc2ccccc2c1=O InChI=1S/C14H9ClN2O/c15-11-5-7-12(8-6-11)17-14(18)13-4-2-1-3-10(13)9-16-17/h1-9H QQJQSWFPMBORPH-UHFFFAOYSA-N 114721 2-(4-chlorophenyl)-1(2H)-phthalazinone::2-(4-chlorophenyl)-1-phthalazinone::2-(4-chlorophenyl)phthalazin-1-one::MLS000540543::SMR000125801::cid_519224 Oxysterols receptor LXR-beta 67506 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114721&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 519224 252664202 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238621 Cc1ccc(CSc2nc3ccncc3[nH]2)cc1 InChI=1S/C14H13N3S/c1-10-2-4-11(5-3-10)9-18-14-16-12-6-7-15-8-13(12)17-14/h2-8H,9H2,1H3,(H,16,17) AOGVVVMNQFKNIM-UHFFFAOYSA-N 114722 2-[(4-methylbenzyl)thio]-3H-imidazo[4,5-c]pyridine::2-[(4-methylphenyl)methylsulfanyl]-3H-imidazo[4,5-c]pyridine::2-[(4-methylphenyl)methylthio]-3H-imidazo[4,5-c]pyridine::MLS000522806::SMR000128072::cid_3551008 Oxysterols receptor LXR-beta 67507 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114722&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3551008 252664203 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238622 COc1cc(ccc1N=CCC(=O)c1cccs1)[N+]([O-])=O InChI=1S/C14H12N2O4S/c1-20-13-9-10(16(18)19)4-5-11(13)15-7-6-12(17)14-3-2-8-21-14/h2-5,7-9H,6H2,1H3 MALRTWANLNTZPJ-UHFFFAOYSA-N 48245 (E)-3-(2-methoxy-4-nitro-anilino)-1-(2-thienyl)prop-2-en-1-one::(E)-3-(2-methoxy-4-nitroanilino)-1-thiophen-2-yl-2-propen-1-one::(E)-3-(2-methoxy-4-nitroanilino)-1-thiophen-2-ylprop-2-en-1-one::(E)-3-[(2-methoxy-4-nitro-phenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one::3-[(2-methoxy-4-nitrophenyl)amino]-1-(2-thienyl)-2-propen-1-one::MLS000537797::SMR000144035::cid_5739690 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48245&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896749 252628541 ZINC08828869 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238623 O=C1C(=CNc2ccccc2)C(=O)c2ccccc12 InChI=1S/C16H11NO2/c18-15-12-8-4-5-9-13(12)16(19)14(15)10-17-11-6-2-1-3-7-11/h1-10,17H RJWGMPWJKXQPAO-UHFFFAOYSA-N 114723 2-(anilinomethylene)-1H-indene-1,3(2H)-dione::2-(anilinomethylene)indane-1,3-quinone::2-(anilinomethylidene)indene-1,3-dione::2-(phenylazanylmethylidene)indene-1,3-dione::MLS000534789::SMR000142245::cid_217228 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114723&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 217228 252664204 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238624 Cc1ccc(cc1)-c1nc(N=NCc2ccncc2)c2ccccc2n1 InChI=1S/C21H17N5/c1-15-6-8-17(9-7-15)20-24-19-5-3-2-4-18(19)21(25-20)26-23-14-16-10-12-22-13-11-16/h2-13H,14H2,1H3 HRKZLOUJWAFMEC-UHFFFAOYSA-N 48254 2-(4-methylphenyl)-N-(pyridin-4-ylmethylideneamino)-4-quinazolinamine::2-(4-methylphenyl)-N-(pyridin-4-ylmethylideneamino)quinazolin-4-amine::MLS000532966::SMR000140404::[2-(p-tolyl)quinazolin-4-yl]-(4-pyridylmethyleneamino)amine::[2-(p-tolyl)quinazolin-4-yl]-[(E)-4-pyridylmethyleneamino]amine::cid_2846763::isonicotinaldehyde [2-(4-methylphenyl)-4-quinazolinyl]hydrazone Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48254&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896751 252628550 ZINC33394731 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238625 Clc1ccccc1NN=c1c(=O)c2ccccc2c1=O InChI=1S/C15H9ClN2O2/c16-11-7-3-4-8-12(11)17-18-13-14(19)9-5-1-2-6-10(9)15(13)20/h1-8,17H OFJOYDJTXCDYHM-UHFFFAOYSA-N 114725 1H-indene-1,2,3-trione 2-[(2-chlorophenyl)hydrazone]::2-[(2-chlorophenyl)hydrazinylidene]indene-1,3-dione::2-[(2-chlorophenyl)hydrazono]indane-1,3-quinone::MLS000532731::SMR000140169::cid_867445 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114725&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 867445 252664205 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238626 CCc1ccc(NC(=O)c2cnn3ccccc23)cc1 InChI=1S/C16H15N3O/c1-2-12-6-8-13(9-7-12)18-16(20)14-11-17-19-10-4-3-5-15(14)19/h3-11H,2H2,1H3,(H,18,20) LOSOOOHTAHWTDO-UHFFFAOYSA-N 97199 MLS000522615::N-(4-ethylphenyl)-3-pyrazolo[1,5-a]pyridinecarboxamide::N-(4-ethylphenyl)pyrazolo[1,5-a]pyridine-3-carboxamide::SMR000127882::cid_6622623 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97199&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6622623 164038443 ZINC05035588 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238627 [O-][N+](=O)c1cccc(c1)N=CCC(=O)c1cccs1 InChI=1S/C13H10N2O3S/c16-12(13-5-2-8-19-13)6-7-14-10-3-1-4-11(9-10)15(17)18/h1-5,7-9H,6H2 VCRGFILYJCNWQE-UHFFFAOYSA-N 114726 (E)-3-(3-nitroanilino)-1-(2-thienyl)prop-2-en-1-one::(E)-3-(3-nitroanilino)-1-thiophen-2-yl-2-propen-1-one::(E)-3-(3-nitroanilino)-1-thiophen-2-ylprop-2-en-1-one::(E)-3-[(3-nitrophenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one::3-[(3-nitrophenyl)amino]-1-(2-thienyl)-2-propen-1-one::MLS000537687::SMR000143911::cid_2211323 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114726&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899727 252664206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238628 NC(=S)NN=Cc1ccc(o1)-c1ccc(Cl)c(Cl)c1 InChI=1S/C12H9Cl2N3OS/c13-9-3-1-7(5-10(9)14)11-4-2-8(18-11)6-16-17-12(15)19/h1-6H,(H3,15,17,19) XPPSSQLRMZVJFH-UHFFFAOYSA-N 114727 1-[(E)-[5-(3,4-dichlorophenyl)furan-2-yl]methylideneamino]thiourea::5-(3,4-dichlorophenyl)-2-furaldehyde thiosemicarbazone::MLS000533260::SMR000140698::[(E)-[5-(3,4-dichlorophenyl)-2-furanyl]methylideneamino]thiourea::[(E)-[5-(3,4-dichlorophenyl)-2-furyl]methyleneamino]thiourea::[(E)-[5-(3,4-dichlorophenyl)furan-2-yl]methylideneamino]thiourea::cid_5342491 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114727&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5342491 252664207 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238629 CN1\C(Sc2ccccc12)=C\C(=O)c1cccs1 InChI=1S/C14H11NOS2/c1-15-10-5-2-3-6-12(10)18-14(15)9-11(16)13-7-4-8-17-13/h2-9H,1H3/b14-9- JMBZNSQGQKVUPF-ZROIWOOFSA-N 49453 (2Z)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-(2-thienyl)ethanone::(2Z)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-thiophen-2-yl-ethanone::(2Z)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-thiophen-2-ylethanone::2-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)-1-(2-thienyl)ethanone::MLS000536852::SMR000143489::cid_1633230 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49453&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1633230 252629730 ZINC04746671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238630 CC(=Nc1ccc(C)cc1)c1sc2ccccc2c1O InChI=1S/C17H15NOS/c1-11-7-9-13(10-8-11)18-12(2)17-16(19)14-5-3-4-6-15(14)20-17/h3-10,19H,1-2H3 IMQYOORYIQDZTK-UHFFFAOYSA-N 114728 (2Z)-2-[1-(4-methylanilino)ethylidene]-1-benzothiophen-3-one::(2Z)-2-[1-(p-toluidino)ethylidene]benzothiophen-3-one::(2Z)-2-[1-[(4-methylphenyl)amino]ethylidene]-1-benzothiophen-3-one::2-[1-p-Tolylamino-eth-(Z)-ylidene]-benzo[b]thiophen-3-one::MLS000550926::SMR000145054::cid_6858996 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114728&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6858996 252664208 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238631 Cc1cc(N2CCOCC2)n2ncc(-c3ccccc3)c2n1 InChI=1S/C17H18N4O/c1-13-11-16(20-7-9-22-10-8-20)21-17(19-13)15(12-18-21)14-5-3-2-4-6-14/h2-6,11-12H,7-10H2,1H3 SUEDPLSNXHDQJF-UHFFFAOYSA-N 48274 4-(5-methyl-3-phenyl-7-pyrazolo[1,5-a]pyrimidinyl)morpholine::4-(5-methyl-3-phenyl-pyrazolo[1,5-a]pyrimidin-7-yl)morpholine::4-(5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)morpholine::5-Methyl-7-morpholin-4-yl-3-phenyl-pyrazolo[1,5-a]pyrimidine::MLS000558888::SMR000149204::cid_3614066 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48274&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3614066 252628570 ZINC05572921 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238632 COc1ccc(cc1)-c1cc(n[nH]1)-c1ccccc1O InChI=1S/C16H14N2O2/c1-20-12-8-6-11(7-9-12)14-10-15(18-17-14)13-4-2-3-5-16(13)19/h2-10,19H,1H3,(H,17,18) AASRUAOBYASXDX-UHFFFAOYSA-N 49458 (6E)-6-[5-(4-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[5-(4-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[5-(4-methoxyphenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::2-[5-(4-Methoxy-phenyl)-1H-pyrazol-3-yl]-phenol::MLS000551030::SMR000145157::cid_6614449 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49458&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6614449 252629735 ZINC13118859 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238633 Cc1cc(NCCCn2ccnc2)n2ncc(-c3ccc(Cl)cc3)c2n1 InChI=1S/C19H19ClN6/c1-14-11-18(22-7-2-9-25-10-8-21-13-25)26-19(24-14)17(12-23-26)15-3-5-16(20)6-4-15/h3-6,8,10-13,22H,2,7,9H2,1H3 SLWUMZKNTLKMGT-UHFFFAOYSA-N 48278 3-(4-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-amine::3-(4-chlorophenyl)-N-(3-imidazol-1-ylpropyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine::3-(4-chlorophenyl)-N-[3-(1-imidazolyl)propyl]-5-methyl-7-pyrazolo[1,5-a]pyrimidinamine::MLS000559109::SMR000149425::[3-(4-Chloro-phenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-yl]-(3-imidazol-1-yl-propyl)-amine::[3-(4-chlorophenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-yl]-(3-imidazol-1-ylpropyl)amine::cid_4886402 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48278&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4886402 252628574 ZINC08577966 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238634 Cc1ccc(C)c(NC(=O)c2ccc3ccccc3n2)c1 InChI=1S/C18H16N2O/c1-12-7-8-13(2)17(11-12)20-18(21)16-10-9-14-5-3-4-6-15(14)19-16/h3-11H,1-2H3,(H,20,21) VQQQTTKPKNHMMQ-UHFFFAOYSA-N 49465 MLS000568162::N-(2,5-dimethylphenyl)-2-quinolinecarboxamide::N-(2,5-dimethylphenyl)quinaldamide::N-(2,5-dimethylphenyl)quinoline-2-carboxamide::SMR000154529::cid_2547832 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49465&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2547832 252629741 ZINC03428387 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238635 C1COc2cc(Nc3nc(cs3)-c3ccccc3)ccc2O1 InChI=1S/C17H14N2O2S/c1-2-4-12(5-3-1)14-11-22-17(19-14)18-13-6-7-15-16(10-13)21-9-8-20-15/h1-7,10-11H,8-9H2,(H,18,19) KAXKKOPKEONSGB-UHFFFAOYSA-N 114729 2,3-dihydro-1,4-benzodioxin-6-yl-(4-phenylthiazol-2-yl)amine;hydrobromide::MLS000569419::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-1,3-thiazol-2-amine;hydrobromide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-2-thiazolamine;hydrobromide::SMR000155005::cid_9551891 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114729&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2325130 252664209 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238636 COc1ccc(cc1)C(=O)Nc1nnc(s1)-c1cccs1 InChI=1S/C14H11N3O2S2/c1-19-10-6-4-9(5-7-10)12(18)15-14-17-16-13(21-14)11-3-2-8-20-11/h2-8H,1H3,(H,15,17,18) HOQITGNXLUTLNE-UHFFFAOYSA-N 114730 4-Methoxy-N-(5-thiophen-2-yl-[1,3,4]thiadiazol-2-yl)-benzamide::4-methoxy-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)benzamide::4-methoxy-N-[5-(2-thienyl)-1,3,4-thiadiazol-2-yl]benzamide::MLS000528098::SMR000120672::cid_3212603 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114730&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3212603 252664210 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238637 COc1ccc(Nc2nc(cs2)-c2ccccc2)cc1 InChI=1S/C16H14N2OS/c1-19-14-9-7-13(8-10-14)17-16-18-15(11-20-16)12-5-3-2-4-6-12/h2-11H,1H3,(H,17,18) NAVZSNBQDOGYKD-UHFFFAOYSA-N 49484 (4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine::MLS000565006::N-(4-methoxyphenyl)-4-phenyl-1,3-thiazol-2-amine::N-(4-methoxyphenyl)-4-phenyl-2-thiazolamine::SMR000152166::cid_1548457 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49484&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1548457 252629760 ZINC05526864 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238638 Cc1ccc2nc(CSc3nc(C)ccc3C#N)[nH]c2c1 InChI=1S/C16H14N4S/c1-10-3-6-13-14(7-10)20-15(19-13)9-21-16-12(8-17)5-4-11(2)18-16/h3-7H,9H2,1-2H3,(H,19,20) UJMMTOFYGMTFAD-UHFFFAOYSA-N 114731 6-methyl-2-[(6-methyl-1H-benzimidazol-2-yl)methylsulfanyl]pyridine-3-carbonitrile::6-methyl-2-[(6-methyl-1H-benzimidazol-2-yl)methylthio]-3-pyridinecarbonitrile::6-methyl-2-[(6-methyl-1H-benzimidazol-2-yl)methylthio]nicotinonitrile::6-methyl-2-{[(5-methyl-1H-benzimidazol-2-yl)methyl]sulfanyl}nicotinonitrile::MLS000537226::SMR000160405::cid_7304501 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114731&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7304501 252664211 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238639 CC(N=Nc1nc2CCCCc2s1)c1ccccc1 InChI=1S/C15H17N3S/c1-11(12-7-3-2-4-8-12)17-18-15-16-13-9-5-6-10-14(13)19-15/h2-4,7-8,11H,5-6,9-10H2,1H3 CSHIGVQPPMCKRO-UHFFFAOYSA-N 114732 4,5,6,7-tetrahydro-1,3-benzothiazol-2(3H)-one (1-phenylethylidene)hydrazone::MLS000545714::N-[(E)-1-phenylethylideneamino]-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine;hydrochloride::SMR000163535::[(E)-1-phenylethylideneamino]-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)amine;hydrochloride::cid_56642823 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114732&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899728 252664212 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238640 Cc1[nH]n(C(N)=S)c(=O)c1N=Nc1ccc(C)cc1C InChI=1S/C13H15N5OS/c1-7-4-5-10(8(2)6-7)15-16-11-9(3)17-18(12(11)19)13(14)20/h4-6,17H,1-3H3,(H2,14,20) SHEHNQOKTGEPEX-UHFFFAOYSA-N 114733 4-(2,4-Dimethyl-phenylazo)-3-methyl-5-oxo-4,5-dihydro-pyrazole-1-carbothioic acid amide::4-(2,4-dimethylphenyl)azo-3-methyl-5-oxo-4H-pyrazole-1-carbothioamide::4-(2,4-dimethylphenyl)azo-5-keto-3-methyl-2-pyrazoline-1-carbothioamide::4-[(2,4-dimethylphenyl)diazenyl]-3-methyl-5-oxidanylidene-4H-pyrazole-1-carbothioamide::4-[(2,4-dimethylphenyl)diazenyl]-3-methyl-5-oxo-4H-pyrazole-1-carbothioamide::MLS000526883::SMR000117357::cid_3106473 Oxysterols receptor LXR-beta 67488 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114733&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6139089 252664213 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238641 Cc1ccc(CN=C2Nc3ccccc3CS2)cc1 InChI=1S/C16H16N2S/c1-12-6-8-13(9-7-12)10-17-16-18-15-5-3-2-4-14(15)11-19-16/h2-9H,10-11H2,1H3,(H,17,18) BWUREMXPFYRLHH-UHFFFAOYSA-N 49507 4H-3,1-benzothiazin-2-yl-(4-methylbenzyl)amine::MLS000543331::N-(4-methylbenzyl)-4H-3,1-benzothiazin-2-amine::N-[(4-methylphenyl)methyl]-4H-3,1-benzothiazin-2-amine::SMR000169300::cid_3721736 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49507&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3721736 252629783 ZINC03052287 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238642 Cn1cc(Cl)c(n1)C(=O)Nc1nc2ccccc2s1 InChI=1S/C12H9ClN4OS/c1-17-6-7(13)10(16-17)11(18)15-12-14-8-4-2-3-5-9(8)19-12/h2-6H,1H3,(H,14,15,18) HYALETWBHGSDOP-UHFFFAOYSA-N 114734 4-Chloro-1-methyl-1H-pyrazole-3-carboxylic acid benzothiazol-2-ylamide::MLS000560315::N-(1,3-benzothiazol-2-yl)-4-chloranyl-1-methyl-pyrazole-3-carboxamide::N-(1,3-benzothiazol-2-yl)-4-chloro-1-methyl-3-pyrazolecarboxamide::N-(1,3-benzothiazol-2-yl)-4-chloro-1-methyl-pyrazole-3-carboxamide::N-(1,3-benzothiazol-2-yl)-4-chloro-1-methylpyrazole-3-carboxamide::SMR000178022::cid_749848 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114734&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 749848 252664214 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238643 COc1ccc(C(N)=S)c(OC)c1 InChI=1S/C9H11NO2S/c1-11-6-3-4-7(9(10)13)8(5-6)12-2/h3-5H,1-2H3,(H2,10,13) KYGPUPQKDUNOLW-UHFFFAOYSA-N 87901 2,4-dimethoxybenzenecarbothioamide::2,4-dimethoxythiobenzamide::MLS000391452::SMR000260488::cid_3857241 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=87901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=87901&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3857241 252660099 ZINC00067494 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238644 [O-][N+](=O)c1ccccc1N=[NH+]Cc1c[n-]c2ccccc12 InChI=1S/C15H11N4O2/c20-19(21)15-8-4-3-7-14(15)18-17-10-11-9-16-13-6-2-1-5-12(11)13/h1-9H,10H2/q-1/p+1 HFJUWLHNMQGRFH-UHFFFAOYSA-O 76435 1-[(Z)-3-indolylidenemethyl]-2-(2-nitrophenyl)hydrazine::1-[(Z)-indol-3-ylidenemethyl]-2-(2-nitrophenyl)diazane::1-[(Z)-indol-3-ylidenemethyl]-2-(2-nitrophenyl)hydrazine::MLS000555664::N-(1H-Indol-3-ylmethylene)-N'-(2-nitro-phenyl)-hydrazine::SMR000175220::cid_5332521 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76435&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91898166 252653614 ZINC13130812 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238645 Cc1ccc2nc(CSc3nc(C)cc(C)c3C#N)[nH]c2c1 InChI=1S/C17H16N4S/c1-10-4-5-14-15(6-10)21-16(20-14)9-22-17-13(8-18)11(2)7-12(3)19-17/h4-7H,9H2,1-3H3,(H,20,21) GPHMYOVIOIYQHA-UHFFFAOYSA-N 114735 4,6-dimethyl-2-[(6-methyl-1H-benzimidazol-2-yl)methylsulfanyl]pyridine-3-carbonitrile::4,6-dimethyl-2-[(6-methyl-1H-benzimidazol-2-yl)methylthio]-3-pyridinecarbonitrile::4,6-dimethyl-2-[(6-methyl-1H-benzimidazol-2-yl)methylthio]nicotinonitrile::4,6-dimethyl-2-{[(5-methyl-1H-benzimidazol-2-yl)methyl]sulfanyl}nicotinonitrile::MLS000537223::SMR000160406::cid_845813 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 845813 252664215 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238646 Fc1ccc(cc1)-c1cn2cc(cc(Cl)c2n1)C(F)(F)F InChI=1S/C14H7ClF4N2/c15-11-5-9(14(17,18)19)6-21-7-12(20-13(11)21)8-1-3-10(16)4-2-8/h1-7H LHUTUFIEQFAVFB-UHFFFAOYSA-N 49517 8-chloranyl-2-(4-fluorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine::8-chloro-2-(4-fluorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine::MLS000547249::SMR000180347::cid_1485610 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49517&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1485610 252629793 ZINC01399532 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238647 Clc1ccc2nc(cn2c1)-c1ccc(Br)s1 InChI=1S/C11H6BrClN2S/c12-10-3-2-9(16-10)8-6-15-5-7(13)1-4-11(15)14-8/h1-6H CFGPYJKNIUPURR-UHFFFAOYSA-N 76438 2-(5-bromanylthiophen-2-yl)-6-chloranyl-imidazo[1,2-a]pyridine::2-(5-bromo-2-thienyl)-6-chloro-imidazo[1,2-a]pyridine::2-(5-bromo-2-thienyl)-6-chloroimidazo[1,2-a]pyridine::2-(5-bromo-2-thiophenyl)-6-chloroimidazo[1,2-a]pyridine::2-(5-bromothiophen-2-yl)-6-chloroimidazo[1,2-a]pyridine::MLS000546882::SMR000180080::cid_3850729 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76438&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3850729 252653617 ZINC04003185 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238648 COc1ccc(cc1)C1=c2cc(OC)ccc2=NC(=NN1)c1cccs1 InChI=1S/C20H17N3O2S/c1-24-14-7-5-13(6-8-14)19-16-12-15(25-2)9-10-17(16)21-20(23-22-19)18-4-3-11-26-18/h3-12,22H,1-2H3 FMDMRXBOCVGROC-UHFFFAOYSA-N 77687 7-Methoxy-5-(4-methoxy-phenyl)-2-thiophen-2-yl-3H-benzo[e][1,2,4]triazepine::7-methoxy-5-(4-methoxyphenyl)-2-(2-thienyl)-4H-1,3,4-benzotriazepine::7-methoxy-5-(4-methoxyphenyl)-2-thiophen-2-yl-4H-1,3,4-benzotriazepine::MLS000527138::SMR000117612::cid_1375020 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77687&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1375020 252654682 ZINC13125631 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238649 CSc1ccccc1-c1nnc(o1)-c1ccccc1 InChI=1S/C15H12N2OS/c1-19-13-10-6-5-9-12(13)15-17-16-14(18-15)11-7-3-2-4-8-11/h2-10H,1H3 XNQSCZPDOBRILD-UHFFFAOYSA-N 49519 2-(2-methylsulfanylphenyl)-5-phenyl-1,3,4-oxadiazole::2-[2-(methylthio)phenyl]-5-phenyl-1,3,4-oxadiazole::MLS000325940::SMR000170101::cid_1484133::methyl 2-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl sulfide Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49519&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1484133 252629795 ZINC01397857 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238650 CSc1nnc(o1)-c1cc2CCc3ccccc3-c2s1 InChI=1S/C15H12N2OS2/c1-19-15-17-16-14(18-15)12-8-10-7-6-9-4-2-3-5-11(9)13(10)20-12/h2-5,8H,6-7H2,1H3 YTESSBCNMNDZIN-UHFFFAOYSA-N 76317 2-(4,5-dihydrobenzo[g][1]benzothiol-2-yl)-5-(methylthio)-1,3,4-oxadiazole::2-(4,5-dihydrobenzo[g][1]benzothiol-2-yl)-5-methylsulfanyl-1,3,4-oxadiazole::2-(4,5-dihydrobenzo[g]benzothiophen-2-yl)-5-(methylthio)-1,3,4-oxadiazole::2-(4,5-dihydronaphtho[1,2-b]thiophen-2-yl)-5-(methylsulfanyl)-1,3,4-oxadiazole::MLS000326827::SMR000179408::cid_4351721 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76317&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4351721 252653496 ZINC04091932 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238651 Clc1ccc(\C=C\c2nc3ccccc3[nH]2)c(Cl)c1 InChI=1S/C15H10Cl2N2/c16-11-7-5-10(12(17)9-11)6-8-15-18-13-3-1-2-4-14(13)19-15/h1-9H,(H,18,19)/b8-6+ ZUMIBXPTGMOQDK-SOFGYWHQSA-N 39783 2-(2,4-dichlorostyryl)-1H-1,3-benzimidazole::2-[(E)-2-(2,4-dichlorophenyl)ethenyl]-1H-benzimidazole::2-[(E)-2-(2,4-dichlorophenyl)vinyl]-1H-benzimidazole::MLS000325842::SMR000169722::cid_6050443 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39783&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6050443 252620669 ZINC04002700 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238652 Cc1ccccc1-c1cc(on1)-c1ccccc1O InChI=1S/C16H13NO2/c1-11-6-2-3-7-12(11)14-10-16(19-17-14)13-8-4-5-9-15(13)18/h2-10,18H,1H3 YKNHGENBUSXLPZ-UHFFFAOYSA-N 49531 (6E)-6-[3-(2-methylphenyl)-2H-1,2-oxazol-5-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[3-(2-methylphenyl)-2H-isoxazol-5-ylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[3-(o-tolyl)-3-isoxazolin-5-ylidene]cyclohexa-2,4-dien-1-one::2-[3-(2-methylphenyl)-5-isoxazolyl]phenol::MLS000570875::SMR000193297::cid_11958868 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49531&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11958868 252629807 ZINC15974419 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238653 Oc1ccccc1-c1cc(no1)-c1ccccc1 InChI=1S/C15H11NO2/c17-14-9-5-4-8-12(14)15-10-13(16-18-15)11-6-2-1-3-7-11/h1-10,17H XWLIMTFPYMGWEB-UHFFFAOYSA-N 49532 (6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-6-(3-phenyl-2H-1,2-oxazol-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-6-(3-phenyl-2H-isoxazol-5-ylidene)-1-cyclohexa-2,4-dienone::(6Z)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::2-(3-phenyl-5-isoxazolyl)phenol::MLS000570866::SMR000187290::cid_5343445 Oxysterols receptor LXR-beta 67472 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49532&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5343445 252629808 ZINC13130481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238654 Fc1cccc(c1)N=CCC(=O)c1cccs1 InChI=1S/C13H10FNOS/c14-10-3-1-4-11(9-10)15-7-6-12(16)13-5-2-8-17-13/h1-5,7-9H,6H2 GDIGEJBUPDZKNJ-UHFFFAOYSA-N 49538 (Z)-3-(3-fluoroanilino)-1-(2-thienyl)prop-2-en-1-one::(Z)-3-(3-fluoroanilino)-1-thiophen-2-yl-2-propen-1-one::(Z)-3-(3-fluoroanilino)-1-thiophen-2-ylprop-2-en-1-one::(Z)-3-[(3-fluorophenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one::3-[(3-fluorophenyl)amino]-1-(2-thienyl)-2-propen-1-one::MLS000574114::SMR000195699::cid_5731334 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49538&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896807 252629814 ZINC04754700 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238655 Fc1ccc(cc1)N=CCC(=O)c1cccs1 InChI=1S/C13H10FNOS/c14-10-3-5-11(6-4-10)15-8-7-12(16)13-2-1-9-17-13/h1-6,8-9H,7H2 UZJLEZYVNYVIND-UHFFFAOYSA-N 114736 (E)-3-(4-fluoroanilino)-1-(2-thienyl)prop-2-en-1-one::(E)-3-(4-fluoroanilino)-1-thiophen-2-yl-2-propen-1-one::(E)-3-(4-fluoroanilino)-1-thiophen-2-ylprop-2-en-1-one::(E)-3-[(4-fluorophenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one::3-[(4-fluorophenyl)amino]-1-(2-thienyl)-2-propen-1-one::MLS000580171::SMR000199702::cid_2204617 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899729 252664216 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238656 NC(=NOC(=O)c1ccccc1Cl)c1ccccc1 InChI=1S/C14H11ClN2O2/c15-12-9-5-4-8-11(12)14(18)19-17-13(16)10-6-2-1-3-7-10/h1-9H,(H2,16,17) ATXRRRCIHZTEEH-UHFFFAOYSA-N 49546 2-chlorobenzoic acid [(Z)-[amino(phenyl)methylene]amino] ester::2-chlorobenzoic acid [(Z)-[amino(phenyl)methylidene]amino] ester::MLS000576943::N'-[(2-chlorobenzoyl)oxy]benzenecarboximidamide::SMR000185421::[(Z)-[amino(phenyl)methylidene]amino] 2-chlorobenzoate::[(Z)-[azanyl(phenyl)methylidene]amino] 2-chloranylbenzoate::cid_5332683 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49546&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5332683 252629822 ZINC04170067 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238657 Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)nc1 InChI=1S/C15H11ClN2OS/c1-9-6-7-12(17-8-9)18-15(19)14-13(16)10-4-2-3-5-11(10)20-14/h2-8H,1H3,(H,17,18,19) GUMUTRKQFWRANF-UHFFFAOYSA-N 43065 3-chloranyl-N-(5-methylpyridin-2-yl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methyl-2-pyridinyl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methyl-2-pyridyl)benzothiophene-2-carboxamide::3-chloro-N-(5-methylpyridin-2-yl)-1-benzothiophene-2-carboxamide::MLS000572006::SMR000194166::cid_903387 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 903387 252623751 ZINC00483533 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238658 NC(=NOC(=O)c1ccc(Cl)cc1Cl)c1ccccc1 InChI=1S/C14H10Cl2N2O2/c15-10-6-7-11(12(16)8-10)14(19)20-18-13(17)9-4-2-1-3-5-9/h1-8H,(H2,17,18) AFSPDMVYLXZASM-UHFFFAOYSA-N 66032 2,4-dichlorobenzoic acid [(Z)-[amino(phenyl)methylene]amino] ester::2,4-dichlorobenzoic acid [(Z)-[amino(phenyl)methylidene]amino] ester::MLS000576961::N'-[(2,4-dichlorobenzoyl)oxy]benzenecarboximidamide::SMR000185439::[(Z)-[amino(phenyl)methylidene]amino] 2,4-dichlorobenzoate::[(Z)-[azanyl(phenyl)methylidene]amino] 2,4-bis(chloranyl)benzoate::cid_5332708 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5332708 252644361 ZINC04577027 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238659 Cc1cc(C)c2c(N)c3cccc(C)c3nc2n1 InChI=1S/C15H15N3/c1-8-5-4-6-11-13(16)12-9(2)7-10(3)17-15(12)18-14(8)11/h4-7H,1-3H3,(H2,16,17,18) WRUVTYDQVPMYDZ-UHFFFAOYSA-N 83759 (2,4,9-trimethylbenzo[b][1,8]naphthyridin-5-yl)amine::2,4,9-Trimethyl-benzo[b][1,8]naphthyridin-5-ylamine::2,4,9-trimethyl-5-benzo[b][1,8]naphthyridinamine::2,4,9-trimethylbenzo[b][1,8]naphthyridin-5-amine::MLS000552981::SMR000178181::cid_698490 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 698490 252658941 ZINC00075835 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238661 CCOC(=O)c1sc2nc(ccc2c1N)-c1ccccc1 InChI=1S/C16H14N2O2S/c1-2-20-16(19)14-13(17)11-8-9-12(18-15(11)21-14)10-6-4-3-5-7-10/h3-9H,2,17H2,1H3 RHLVCLJIDVQESM-UHFFFAOYSA-N 114737 3-amino-6-phenyl-2-thieno[2,3-b]pyridinecarboxylic acid ethyl ester::3-amino-6-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid ethyl ester::MLS000583378::SMR000185191::cid_690223::ethyl 3-amino-6-phenylthieno[2,3-b]pyridine-2-carboxylate::ethyl 3-azanyl-6-phenyl-thieno[2,3-b]pyridine-2-carboxylate Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 690223 252664217 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238662 NNc1nc(nc2sc3CCCCc3c12)-c1ccccc1 InChI=1S/C16H16N4S/c17-20-15-13-11-8-4-5-9-12(11)21-16(13)19-14(18-15)10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9,17H2,(H,18,19,20) FJJSQIUPILXYQS-UHFFFAOYSA-N 96034 (2-Phenyl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazine::(2-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)diazane::(2-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)hydrazine::(2-phenyl-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]pyrimidin-4-yl)hydrazine::MLS000594970::SMR000218184::cid_947382 Oxysterols receptor LXR-beta 67518 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96034&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 947382 164037278 ZINC00546335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238663 Nc1nc(nc2sc3CCCCc3c12)-c1ccccc1 InChI=1S/C16H15N3S/c17-14-13-11-8-4-5-9-12(11)20-16(13)19-15(18-14)10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9H2,(H2,17,18,19) FBXQBNOGCILJCD-UHFFFAOYSA-N 49587 (2-phenyl-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]pyrimidin-4-yl)amine::2-Phenyl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-ylamine::2-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-amine::MLS000561401::SMR000177806::cid_337817 Oxysterols receptor LXR-beta 67489 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49587&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 337817 252629862 ZINC03071497 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238664 Cc1ccnc(NC(=S)NC(=O)c2cccs2)c1 InChI=1S/C12H11N3OS2/c1-8-4-5-13-10(7-8)14-12(17)15-11(16)9-3-2-6-18-9/h2-7H,1H3,(H2,13,14,15,16,17) MEJUVKDBEDNEBI-UHFFFAOYSA-N 114738 1-(4-Methyl-pyridin-2-yl)-3-(thiophene-2-carbonyl)-thiourea::MLS000567458::N-[(4-methyl-2-pyridyl)thiocarbamoyl]thiophene-2-carboxamide::N-[(4-methylpyridin-2-yl)carbamothioyl]thiophene-2-carboxamide::N-[[(4-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamide::SMR000177673::cid_817344 Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 817344 252664218 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238665 NC(=O)c1ccsc1NC(=O)c1ccc2CCCCc2c1 InChI=1S/C16H16N2O2S/c17-14(19)13-7-8-21-16(13)18-15(20)12-6-5-10-3-1-2-4-11(10)9-12/h5-9H,1-4H2,(H2,17,19)(H,18,20) YPVPTDGLGFOXBD-UHFFFAOYSA-N 49622 2-(5,6,7,8-tetrahydronaphthalen-2-ylcarbonylamino)thiophene-3-carboxamide::2-(5,6,7,8-tetrahydronaphthalene-2-carbonylamino)thiophene-3-carboxamide::2-(tetralin-6-carbonylamino)thiophene-3-carboxamide::2-[[oxo(5,6,7,8-tetrahydronaphthalen-2-yl)methyl]amino]-3-thiophenecarboxamide::MLS000724714::SMR000237558::cid_4158664 Oxysterols receptor LXR-beta 67507 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49622&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4158664 252629897 ZINC04275755 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238666 Cn1c2ccccc2nc(\C=C\c2ccccc2)c1=O InChI=1S/C17H14N2O/c1-19-16-10-6-5-9-14(16)18-15(17(19)20)12-11-13-7-3-2-4-8-13/h2-12H,1H3/b12-11+ OZMKUHPCTODLRM-VAWYXSNFSA-N 1735 cid_6166749 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=1735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=1735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6166749 252614756 ZINC04100405 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238667 Fc1cccc(F)c1\C=C\c1ccc2ccccc2n1 InChI=1S/C17H11F2N/c18-15-5-3-6-16(19)14(15)11-10-13-9-8-12-4-1-2-7-17(12)20-13/h1-11H/b11-10+ WSACSADFZCIBQG-ZHACJKMWSA-N 93791 2-[(E)-2-(2,6-difluorophenyl)ethenyl]quinoline::2-[(E)-2-(2,6-difluorophenyl)vinyl]quinoline::2-[(E)-2-[2,6-bis(fluoranyl)phenyl]ethenyl]quinoline::MLS000417981::SMR000264741::cid_6224185 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93791&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6224185 164035035 ZINC05637348 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238669 O=C(\C=C\c1cccs1)N1CCc2ccccc12 InChI=1S/C15H13NOS/c17-15(8-7-13-5-3-11-18-13)16-10-9-12-4-1-2-6-14(12)16/h1-8,11H,9-10H2/b8-7+ AGFMCRQYCDIVNO-BQYQJAHWSA-N 49636 (E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-propen-1-one::(E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-prop-2-en-1-one::(E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-ylprop-2-en-1-one::(E)-1-indolin-1-yl-3-(2-thienyl)prop-2-en-1-one::1-[3-(2-thienyl)acryloyl]indoline::MLS000678854::SMR000269910::cid_885474 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49636&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 885474 252629911 ZINC00457757 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238670 Fc1ccc2c(Cl)c(sc2c1)C(=O)NC1=NCCS1 InChI=1S/C12H8ClFN2OS2/c13-9-7-2-1-6(14)5-8(7)19-10(9)11(17)16-12-15-3-4-18-12/h1-2,5H,3-4H2,(H,15,16,17) WIYIHXHWMONCNB-UHFFFAOYSA-N 114739 3-chloranyl-N-(4,5-dihydro-1,3-thiazol-2-yl)-6-fluoranyl-1-benzothiophene-2-carboxamide::3-chloro-6-fluoro-N-(2-thiazolin-2-yl)benzothiophene-2-carboxamide::3-chloro-N-(4,5-dihydro-1,3-thiazol-2-yl)-6-fluoro-1-benzothiophene-2-carboxamide::3-chloro-N-(4,5-dihydrothiazol-2-yl)-6-fluoro-1-benzothiophene-2-carboxamide::MLS000389777::SMR000256051::cid_2386708 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search K3T 5MXV 2386708 252664219 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238671 CC(C)(C)NC(=O)NC(=O)COc1ccc(Br)cc1Br InChI=1S/C13H16Br2N2O3/c1-13(2,3)17-12(19)16-11(18)7-20-10-5-4-8(14)6-9(10)15/h4-6H,7H2,1-3H3,(H2,16,17,18,19) QSMNMGLAKWUCTJ-UHFFFAOYSA-N 69043 2-[2,4-bis(bromanyl)phenoxy]-N-(tert-butylcarbamoyl)ethanamide::MLS000388683::N-(tert-butylcarbamoyl)-2-(2,4-dibromophenoxy)acetamide::N-[(tert-butylamino)-oxomethyl]-2-(2,4-dibromophenoxy)acetamide::SMR000254856::cid_2632575 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69043&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2632575 252647215 ZINC03515558 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238672 CC(N=Nc1nc2ccccc2s1)c1cccs1 InChI=1S/C13H11N3S2/c1-9(11-7-4-8-17-11)15-16-13-14-10-5-2-3-6-12(10)18-13/h2-9H,1H3 ONVDGJXRMVWIJE-UHFFFAOYSA-N 96064 1,3-benzothiazol-2-yl-[(E)-1-(2-thienyl)ethylideneamino]amine::MLS000390974::N-[(E)-1-thiophen-2-ylethylideneamino]-1,3-benzothiazol-2-amine::SMR000260011::cid_9635036 Oxysterols receptor LXR-beta 67514 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96064&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899588 164037308 ZINC04964377 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238673 CN1C(=O)\C(=N/NC(=O)c2ccoc2C)c2ccccc12 InChI=1S/C15H13N3O3/c1-9-10(7-8-21-9)14(19)17-16-13-11-5-3-4-6-12(11)18(2)15(13)20/h3-8H,1-2H3,(H,17,19)/b16-13- QDZYXBYFXXIABC-SSZFMOIBSA-N 114740 2-methyl-N-[(Z)-(1-methyl-2-oxidanylidene-indol-3-ylidene)amino]furan-3-carboxamide::2-methyl-N-[(Z)-(1-methyl-2-oxo-3-indolylidene)amino]-3-furancarboxamide::2-methyl-N-[(Z)-(1-methyl-2-oxoindol-3-ylidene)amino]furan-3-carboxamide::MLS000416846::N-[(Z)-(2-keto-1-methyl-indolin-3-ylidene)amino]-2-methyl-3-furamide::SMR000241784::cid_6217008 Oxysterols receptor LXR-beta 67481 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6217008 252664220 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238674 Clc1ccccc1C=NNC1=Nc2cccc3cccc1c23 InChI=1S/C18H12ClN3/c19-15-9-2-1-5-13(15)11-20-22-18-14-8-3-6-12-7-4-10-16(21-18)17(12)14/h1-11H,(H,21,22) GWWLAHNKGIJBJK-UHFFFAOYSA-N 43425 MLS000392773::N-[(2-chlorophenyl)methylideneamino]-2-benzo[cd]indolamine::N-[(2-chlorophenyl)methylideneamino]benzo[cd]indol-2-amine::SMR000261714::benzo[cd]indol-2-yl-[(2-chlorobenzylidene)amino]amine::benzo[cd]indol-2-yl-[(E)-(2-chlorobenzylidene)amino]amine::cid_2315072 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43425&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6899625 252624106 ZINC33402460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238675 N(N=Cc1ccccc1)C1=Nc2cccc3cccc1c23 InChI=1S/C18H13N3/c1-2-6-13(7-3-1)12-19-21-18-15-10-4-8-14-9-5-11-16(20-18)17(14)15/h1-12H,(H,20,21) BHVRGHUCIOBZDB-UHFFFAOYSA-N 51101 (benzalamino)-benzo[cd]indol-2-yl-amine::MLS000392783::N-(benzylideneamino)benzo[cd]indol-2-amine::N-[(phenylmethylene)amino]-2-benzo[cd]indolamine::N-[(phenylmethylidene)amino]benzo[cd]indol-2-amine::SMR000261715::[(E)-benzalamino]-benzo[cd]indol-2-yl-amine::cid_2315076 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51101&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6899626 252631337 ZINC06440858 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238676 Cc1cnc(NC(=O)c2sc3ccccc3c2Cl)s1 InChI=1S/C13H9ClN2OS2/c1-7-6-15-13(18-7)16-12(17)11-10(14)8-4-2-3-5-9(8)19-11/h2-6H,1H3,(H,15,16,17) PETQNGKAFAHVEX-UHFFFAOYSA-N 76503 3-chloranyl-N-(5-methyl-1,3-thiazol-2-yl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methyl-1,3-thiazol-2-yl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methyl-2-thiazolyl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methylthiazol-2-yl)benzothiophene-2-carboxamide::MLS000334487::SMR000249245::cid_2523343 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76503&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2523343 252653681 ZINC03404622 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238677 OC(=O)c1cccc(c1)N=NCc1cccs1 InChI=1S/C12H10N2O2S/c15-12(16)9-3-1-4-10(7-9)14-13-8-11-5-2-6-17-11/h1-7H,8H2,(H,15,16) NJDHUEMYUNJCEC-UHFFFAOYSA-N 49676 3-[(N''E)-N''-(2-thenylidene)hydrazino]benzoic acid::3-[(N'E)-N'-(2-thenylidene)hydrazino]benzoic acid::3-[2-(thiophen-2-ylmethylidene)hydrazinyl]benzoic acid::3-[N'-(2-thenylidene)hydrazino]benzoic acid::MLS000336751::SMR000244066::cid_3687019 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49676&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896829 252629951 ZINC13143470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238678 CSC1=NC(=O)C(N1)=Cc1c[nH]c2ccccc12 InChI=1S/C13H11N3OS/c1-18-13-15-11(12(17)16-13)6-8-7-14-10-5-3-2-4-9(8)10/h2-7,14H,1H3,(H,15,16,17) MRDGQLKPAZJMQY-UHFFFAOYSA-N 114742 (5Z)-5-(1H-indol-3-ylmethylene)-2-(methylthio)-2-imidazolin-4-one::(5Z)-5-(1H-indol-3-ylmethylidene)-2-(methylthio)-1H-imidazol-4-one::(5Z)-5-(1H-indol-3-ylmethylidene)-2-methylsulfanyl-1H-imidazol-4-one::5-(1H-indol-3-ylmethylene)-2-(methylsulfanyl)-3,5-dihydro-4H-imidazol-4-one::MLS000700869::SMR000231390::cid_5471247 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5471247 252664221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238679 Cc1[nH]n(C(N)=S)c(=O)c1N=Nc1ccc(C)c(C)c1 InChI=1S/C13H15N5OS/c1-7-4-5-10(6-8(7)2)15-16-11-9(3)17-18(12(11)19)13(14)20/h4-6,17H,1-3H3,(H2,14,20) RHBXXKXINVFILS-UHFFFAOYSA-N 114743 (4Z)-4-[(3,4-dimethylphenyl)hydrazinylidene]-3-methyl-5-oxidanylidene-pyrazole-1-carbothioamide::(4Z)-4-[(3,4-dimethylphenyl)hydrazinylidene]-3-methyl-5-oxo-1-pyrazolecarbothioamide::(4Z)-4-[(3,4-dimethylphenyl)hydrazinylidene]-3-methyl-5-oxopyrazole-1-carbothioamide::(4Z)-4-[(3,4-dimethylphenyl)hydrazono]-5-keto-3-methyl-2-pyrazoline-1-carbothioamide::4-[(3,4-dimethylphenyl)hydrazono]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothioamide::MLS000704517::SMR000231463::cid_5411098 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5411098 252664222 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238680 Cc1cc(-c2ccccc2)n2ncc(-c3ccccc3)c2n1 InChI=1S/C19H15N3/c1-14-12-18(16-10-6-3-7-11-16)22-19(21-14)17(13-20-22)15-8-4-2-5-9-15/h2-13H,1H3 RPRKTTBEGCMEHF-UHFFFAOYSA-N 114744 5-methyl-3,7-diphenyl-pyrazolo[1,5-a]pyrimidine::5-methyl-3,7-diphenylpyrazolo[1,5-a]pyrimidine::MLS000681210::SMR000269480::cid_832119 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 832119 252664223 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238681 Cc1ccc(cc1)C1=Nc2ccccc2N=C(C1)C(Cl)Cl InChI=1S/C17H14Cl2N2/c1-11-6-8-12(9-7-11)15-10-16(17(18)19)21-14-5-3-2-4-13(14)20-15/h2-9,17H,10H2,1H3 SXTHRXQRBXWCJH-UHFFFAOYSA-N 114745 2-(dichloromethyl)-4-(4-methylphenyl)-3H-1,5-benzodiazepine::4-(dichloromethyl)-2-(4-methylphenyl)-3H-1,5-benzodiazepine::4-(dichloromethyl)-2-(p-tolyl)-3H-1,5-benzodiazepine::4-[bis(chloranyl)methyl]-2-(4-methylphenyl)-3H-1,5-benzodiazepine::MLS000728204::SMR000306897::cid_685576 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 685576 252664224 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238682 Oc1ccccc1C=Cc1noc(n1)-c1ccccc1O InChI=1S/C16H12N2O3/c19-13-7-3-1-5-11(13)9-10-15-17-16(21-18-15)12-6-2-4-8-14(12)20/h1-10,19-20H OUGQQERBJUGIMD-UHFFFAOYSA-N 76519 (6E)-6-[(2E)-2-[(5Z)-5-(6-ketocyclohexa-2,4-dien-1-ylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[(2E)-2-[(5Z)-5-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[(2E)-2-[(5Z)-5-(6-oxo-1-cyclohexa-2,4-dienylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[(2E)-2-[(5Z)-5-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]cyclohexa-2,4-dien-1-one::2-{2-[5-(2-hydroxyphenyl)-1,2,4-oxadiazol-3-yl]vinyl}phenol::MLS000626734::SMR000299118::cid_16188892 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76519&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16188892 252653697 ZINC04171743 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238683 Cc1csc(NC(=O)Nc2ccccc2[N+]([O-])=O)n1 InChI=1S/C11H10N4O3S/c1-7-6-19-11(12-7)14-10(16)13-8-4-2-3-5-9(8)15(17)18/h2-6H,1H3,(H2,12,13,14,16) LQYSRVCLRUOTQB-UHFFFAOYSA-N 114746 1-(4-methyl-1,3-thiazol-2-yl)-3-(2-nitrophenyl)urea::1-(4-methyl-2-thiazolyl)-3-(2-nitrophenyl)urea::1-(4-methylthiazol-2-yl)-3-(2-nitrophenyl)urea::MLS000672095::N-(4-methyl-1,3-thiazol-2-yl)-N'-(2-nitrophenyl)urea::SMR000293525::cid_2950184 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2950184 252664225 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238684 Brc1ccc(NC(=S)NC(=O)c2cccs2)nc1 InChI=1S/C11H8BrN3OS2/c12-7-3-4-9(13-6-7)14-11(17)15-10(16)8-2-1-5-18-8/h1-6H,(H2,13,14,15,16,17) ZYMDJTMLIHWJFO-UHFFFAOYSA-N 114747 MLS000665983::N-[(5-bromanylpyridin-2-yl)carbamothioyl]thiophene-2-carboxamide::N-[(5-bromo-2-pyridyl)thiocarbamoyl]thiophene-2-carboxamide::N-[(5-bromopyridin-2-yl)carbamothioyl]thiophene-2-carboxamide::N-[[(5-bromo-2-pyridinyl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamide::N-{[(5-bromo-2-pyridinyl)amino]carbonothioyl}-2-thiophenecarboxamide::SMR000268911::cid_739034 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 739034 252664226 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238685 Cc1nc(NC(=O)c2cccs2)ccc1Br InChI=1S/C11H9BrN2OS/c1-7-8(12)4-5-10(13-7)14-11(15)9-3-2-6-16-9/h2-6H,1H3,(H,13,14,15) AZDOGCVSSJSWGH-UHFFFAOYSA-N 49785 MLS000662240::N-(5-bromanyl-6-methyl-pyridin-2-yl)thiophene-2-carboxamide::N-(5-bromo-6-methyl-2-pyridinyl)-2-thiophenecarboxamide::N-(5-bromo-6-methyl-2-pyridyl)thiophene-2-carboxamide::N-(5-bromo-6-methylpyridin-2-yl)thiophene-2-carboxamide::SMR000293150::cid_834138 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49785&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 834138 252630060 ZINC00359977 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238686 COc1cccc(c1)-c1nc(no1)-c1cccs1 InChI=1S/C13H10N2O2S/c1-16-10-5-2-4-9(8-10)13-14-12(15-17-13)11-6-3-7-18-11/h2-8H,1H3 YCPYSZXBSIVBQG-UHFFFAOYSA-N 114748 5-(3-methoxyphenyl)-3-(2-thienyl)-1,2,4-oxadiazole::5-(3-methoxyphenyl)-3-thiophen-2-yl-1,2,4-oxadiazole::MLS000674346::SMR000297310::cid_718728 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114748&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 718728 252664227 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238687 Cc1cc(ccc1F)N=CCC(=O)c1cccs1 InChI=1S/C14H12FNOS/c1-10-9-11(4-5-12(10)15)16-7-6-13(17)14-3-2-8-18-14/h2-5,7-9H,6H2,1H3 ZIIFJKSQEHVLIG-UHFFFAOYSA-N 49799 (E)-3-(4-fluoro-3-methyl-anilino)-1-(2-thienyl)prop-2-en-1-one::(E)-3-(4-fluoro-3-methylanilino)-1-thiophen-2-yl-2-propen-1-one::(E)-3-(4-fluoro-3-methylanilino)-1-thiophen-2-ylprop-2-en-1-one::(E)-3-[(4-fluoranyl-3-methyl-phenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one::3-[(4-fluoro-3-methylphenyl)amino]-1-(2-thienyl)-2-propen-1-one::MLS000671999::SMR000294505::cid_2211284 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49799&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896847 252630074 ZINC02857988 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238688 Oc1cccc(CN=Nc2cccc3cccnc23)c1 InChI=1S/C16H13N3O/c20-14-7-1-4-12(10-14)11-18-19-15-8-2-5-13-6-3-9-17-16(13)15/h1-10,20H,11H2 ZNYHMSCZUCMHEP-UHFFFAOYSA-N 49805 3-[(8-quinolinylhydrazinylidene)methyl]phenol::3-[(8-quinolylhydrazono)methyl]phenol::3-[(E)-(8-quinolylhydrazono)methyl]phenol::3-[(quinolin-8-ylhydrazinylidene)methyl]phenol::MLS000713447::SMR000272928::cid_2856025 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49805&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896849 252630080 ZINC33398799 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238689 Cc1ccc(cc1)-c1cc2nc(C)cc(C)n2n1 InChI=1S/C15H15N3/c1-10-4-6-13(7-5-10)14-9-15-16-11(2)8-12(3)18(15)17-14/h4-9H,1-3H3 UVVMCIKINUABHH-UHFFFAOYSA-N 114750 5,7-dimethyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine::5,7-dimethyl-2-(p-tolyl)pyrazolo[1,5-a]pyrimidine::MLS000711692::SMR000281459::cid_761947 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 761947 252664228 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238690 Oc1cccc(c1)-c1nc2cc(ccc2o1)[N+]([O-])=O InChI=1S/C13H8N2O4/c16-10-3-1-2-8(6-10)13-14-11-7-9(15(17)18)4-5-12(11)19-13/h1-7,16H UCTFKBGKVAFVLT-UHFFFAOYSA-N 114751 3-(5-nitro-1,3-benzoxazol-2-yl)phenol::MLS000715569::SMR000275548::cid_1160269 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1160269 252664229 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238691 Fc1cccc2sc(C(=O)Nc3ccccn3)c(Cl)c12 InChI=1S/C14H8ClFN2OS/c15-12-11-8(16)4-3-5-9(11)20-13(12)14(19)18-10-6-1-2-7-17-10/h1-7H,(H,17,18,19) QJFIHMHMBUXRIV-UHFFFAOYSA-N 49824 3-chloranyl-4-fluoranyl-N-pyridin-2-yl-1-benzothiophene-2-carboxamide::3-chloro-4-fluoro-N-(2-pyridinyl)-1-benzothiophene-2-carboxamide::3-chloro-4-fluoro-N-(2-pyridyl)benzothiophene-2-carboxamide::3-chloro-4-fluoro-N-2-pyridinyl-1-benzothiophene-2-carboxamide::3-chloro-4-fluoro-N-pyridin-2-yl-1-benzothiophene-2-carboxamide::MLS000684152::SMR000295829::cid_1244206 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49824&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1244206 252630099 ZINC01052235 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238692 O=C(Nc1ccccc1)Nc1cccc2nsnc12 InChI=1S/C13H10N4OS/c18-13(14-9-5-2-1-3-6-9)15-10-7-4-8-11-12(10)17-19-16-11/h1-8H,(H2,14,15,18) SSGUWQAALJPDJC-UHFFFAOYSA-N 114752 1-(2,1,3-benzothiadiazol-4-yl)-3-phenyl-urea::1-(2,1,3-benzothiadiazol-4-yl)-3-phenylurea::1-phenyl-3-piazthiol-4-yl-urea::MLS000708464::SMR000287931::cid_748227 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 748227 252664230 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238693 CC(C)c1ccc(cc1)-n1nc2ccc(N)cc2n1 InChI=1S/C15H16N4/c1-10(2)11-3-6-13(7-4-11)19-17-14-8-5-12(16)9-15(14)18-19/h3-10H,16H2,1-2H3 ASQLLSICFDWTQD-UHFFFAOYSA-N 114753 (2-p-cumenylbenzotriazol-5-yl)amine::2-(4-propan-2-ylphenyl)-5-benzotriazolamine::2-(4-propan-2-ylphenyl)benzotriazol-5-amine::MLS000718708::SMR000290976::cid_960810 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 960810 252664231 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238694 Cc1ccc2c(cc3[nH]c4ccccc4nc23)c1 InChI=1S/C16H12N2/c1-10-6-7-12-11(8-10)9-15-16(12)18-14-5-3-2-4-13(14)17-15/h2-9,17H,1H3 PNRPFKVWZOAOLA-UHFFFAOYSA-N 114754 2-methyl-11H-indeno[1,2-b]quinoxaline::MLS000728106::SMR000306799::cid_616082 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899730 252664232 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238695 Cc1ccsc1CN=Nc1cccc(c1)C(O)=O InChI=1S/C13H12N2O2S/c1-9-5-6-18-12(9)8-14-15-11-4-2-3-10(7-11)13(16)17/h2-7H,8H2,1H3,(H,16,17) BEUFDGUFNAXBJT-UHFFFAOYSA-N 49882 3-[(N''E)-N''-[(3-methyl-2-thienyl)methylene]hydrazino]benzoic acid::3-[(N'E)-N'-[(3-methyl-2-thienyl)methylene]hydrazino]benzoic acid::3-[2-[(3-methyl-2-thiophenyl)methylidene]hydrazinyl]benzoic acid::3-[2-[(3-methylthiophen-2-yl)methylidene]hydrazinyl]benzoic acid::3-[N'-[(3-methyl-2-thienyl)methylene]hydrazino]benzoic acid::3-{(2E)-2-[(3-methylthien-2-yl)methylene]hydrazino}benzoic acid::MLS000673314::SMR000314555::cid_5025342 Oxysterols receptor LXR-beta 67539 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49882&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896858 252630157 ZINC13133445 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238696 CCOC(=O)c1s\c(=N/C(=O)c2cccs2)n(C)c1C InChI=1S/C13H14N2O3S2/c1-4-18-12(17)10-8(2)15(3)13(20-10)14-11(16)9-6-5-7-19-9/h5-7H,4H2,1-3H3/b14-13- UWHDIVYSYWNAEV-YPKPFQOOSA-N 49889 3,4-dimethyl-2-(2-thenoylimino)-4-thiazoline-5-carboxylic acid ethyl ester::3,4-dimethyl-2-[oxo(thiophen-2-yl)methyl]imino-5-thiazolecarboxylic acid ethyl ester::MLS000678948::SMR000323343::cid_4122444::ethyl 3,4-dimethyl-2-(thiophene-2-carbonylimino)-1,3-thiazole-5-carboxylate::ethyl 3,4-dimethyl-2-thiophen-2-ylcarbonylimino-1,3-thiazole-5-carboxylate Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49889&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4122444 252630164 ZINC13139467 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238697 CCOC(=O)c1s\c(=N/C(=O)c2ccc(Cl)s2)n(C)c1C InChI=1S/C13H13ClN2O3S2/c1-4-19-12(18)10-7(2)16(3)13(21-10)15-11(17)8-5-6-9(14)20-8/h5-6H,4H2,1-3H3/b15-13- SYMZLNUWBPNEIT-SQFISAMPSA-N 114756 2-(5-chlorothiophene-2-carbonyl)imino-3,4-dimethyl-4-thiazoline-5-carboxylic acid ethyl ester::2-[(5-chloro-2-thiophenyl)-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester::MLS000678967::SMR000323364::cid_3460648::ethyl 2-(5-chloranylthiophen-2-yl)carbonylimino-3,4-dimethyl-1,3-thiazole-5-carboxylate::ethyl 2-(5-chlorothiophene-2-carbonyl)imino-3,4-dimethyl-1,3-thiazole-5-carboxylate Oxysterols receptor LXR-beta 67487 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3460648 252664233 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238698 Nc1nn(cc1-c1ccc(Cl)cc1)-c1cccc(F)n1 InChI=1S/C14H10ClFN4/c15-10-6-4-9(5-7-10)11-8-20(19-14(11)17)13-3-1-2-12(16)18-13/h1-8H,(H2,17,19) DTVVDWOJSTZXJT-UHFFFAOYSA-N 49903 4-(4-chlorophenyl)-1-(6-fluoranylpyridin-2-yl)pyrazol-3-amine::4-(4-chlorophenyl)-1-(6-fluoro-2-pyridinyl)-1H-pyrazol-3-amine::4-(4-chlorophenyl)-1-(6-fluoro-2-pyridinyl)-3-pyrazolamine::4-(4-chlorophenyl)-1-(6-fluoropyridin-2-yl)pyrazol-3-amine::MLS000694605::SMR000333274::[4-(4-chlorophenyl)-1-(6-fluoro-2-pyridyl)pyrazol-3-yl]amine::cid_1478416 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49903&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1478416 252630177 ZINC01391065 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238699 CC(C)c1ccc(cc1)-n1cnn(-c2ncccc2[N+]([O-])=O)c1=O InChI=1S/C16H15N5O3/c1-11(2)12-5-7-13(8-6-12)19-10-18-20(16(19)22)15-14(21(23)24)4-3-9-17-15/h3-11H,1-2H3 GRAYRERDOKLXBX-UHFFFAOYSA-N 49908 2-(3-nitro-2-pyridinyl)-4-(4-propan-2-ylphenyl)-1,2,4-triazol-3-one::2-(3-nitro-2-pyridyl)-4-p-cumenyl-1,2,4-triazol-3-one::2-(3-nitropyridin-2-yl)-4-(4-propan-2-ylphenyl)-1,2,4-triazol-3-one::4-(4-isopropylphenyl)-2-(3-nitro-2-pyridinyl)-2,4-dihydro-3H-1,2,4-triazol-3-one::MLS000764220::SMR000335042::cid_1480901 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49908&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1480901 252630182 ZINC01393905 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238700 Cc1nn(-c2ccc(Cl)cc2)c(=O)c2ccccc12 InChI=1S/C15H11ClN2O/c1-10-13-4-2-3-5-14(13)15(19)18(17-10)12-8-6-11(16)7-9-12/h2-9H,1H3 QZUJICHPSGQZMU-UHFFFAOYSA-N 114757 2-(4-chlorophenyl)-4-methyl-1(2H)-phthalazinone::2-(4-chlorophenyl)-4-methyl-1-phthalazinone::2-(4-chlorophenyl)-4-methyl-phthalazin-1-one::2-(4-chlorophenyl)-4-methylphthalazin-1-one::MLS000764186::SMR000335023::cid_3454514 Oxysterols receptor LXR-beta 67507 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114757&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3454514 252664234 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238701 Cc1c(-c2ccccn2)c(=O)[nH]n1-c1ccc(F)cc1 InChI=1S/C15H12FN3O/c1-10-14(13-4-2-3-9-17-13)15(20)18-19(10)12-7-5-11(16)6-8-12/h2-9H,1H3,(H,18,20) QZZHZDLTRHSVBX-UHFFFAOYSA-N 114758 1-(4-fluorophenyl)-5-methyl-4-(2-pyridinyl)-1H-pyrazol-3-ol::1-(4-fluorophenyl)-5-methyl-4-(2-pyridyl)-3-pyrazolin-3-one::2-(4-fluorophenyl)-3-methyl-4-(2-pyridinyl)-1H-pyrazol-5-one::2-(4-fluorophenyl)-3-methyl-4-pyridin-2-yl-1H-pyrazol-5-one::MLS000736352::SMR000338302::cid_3816222 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114758&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3816222 252664235 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238702 Cc1ccc(cc1)-c1nc2ccsc2c(=O)[nH]1 InChI=1S/C13H10N2OS/c1-8-2-4-9(5-3-8)12-14-10-6-7-17-11(10)13(16)15-12/h2-7H,1H3,(H,14,15,16) WMMVFPDZGPLXSU-UHFFFAOYSA-N 114759 2-(4-methylphenyl)-1H-thieno[3,2-d]pyrimidin-4-one::2-(4-methylphenyl)thieno[3,2-d]pyrimidin-4-ol::2-(p-tolyl)-1H-thieno[3,2-d]pyrimidin-4-one::MLS000736332::SMR000338282::cid_3817062 Oxysterols receptor LXR-beta 67516 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3817062 252664236 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238703 Cc1cccc(c1)-c1cc2c(N=O)c3ccccc3c2n[nH]1 InChI=1S/C18H13N3O/c1-11-5-4-6-12(9-11)16-10-15-17(20-19-16)13-7-2-3-8-14(13)18(15)21-22/h2-10,19H,1H3 KKEAHXQAZJATBP-UHFFFAOYSA-N 114760 3-(3-methylphenyl)-5-nitroso-2H-indeno[1,2-c]pyridazine::3-(3-methylphenyl)-5H-indeno[1,2-c]pyridazin-5-one oxime::3-(m-tolyl)-5-nitroso-2H-indeno[1,2-c]pyridazine::MLS000721481::SMR000337106::cid_1489562 Oxysterols receptor LXR-beta 67519 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1489562 252664237 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238704 O=C(Nc1nc2ccccc2s1)c1ccccc1 InChI=1S/C14H10N2OS/c17-13(10-6-2-1-3-7-10)16-14-15-11-8-4-5-9-12(11)18-14/h1-9H,(H,15,16,17) FZVLVMRGZRRBFD-UHFFFAOYSA-N 114761 MLS001033258::N-(1,3-benzothiazol-2-yl)benzamide::SMR000363752::cid_689669 Oxysterols receptor LXR-beta 67449 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114761&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 689669 252664238 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238705 Cc1ccc2n(C)\c(=N\C(=O)c3cccs3)sc2c1 InChI=1S/C14H12N2OS2/c1-9-5-6-10-12(8-9)19-14(16(10)2)15-13(17)11-4-3-7-18-11/h3-8H,1-2H3/b15-14- VFAXDRSABFWDBR-PFONDFGASA-N 114762 MLS001004688::N-(3,6-dimethyl-1,3-benzothiazol-2-ylidene)-2-thiophenecarboxamide::N-(3,6-dimethyl-1,3-benzothiazol-2-ylidene)thiophene-2-carboxamide::SMR000348271::cid_2321009 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114762&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2321009 252664239 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238706 CC(C)NC1=NN=C(CS1)c1cccs1 InChI=1S/C10H13N3S2/c1-7(2)11-10-13-12-8(6-15-10)9-4-3-5-14-9/h3-5,7H,6H2,1-2H3,(H,11,13) JZGCHRQNUFEPRL-UHFFFAOYSA-N 114763 MLS001032945::N-propan-2-yl-5-thiophen-2-yl-6H-1,3,4-thiadiazin-2-amine::SMR000363521::cid_3585427::isopropyl-[5-(2-thienyl)-6H-1,3,4-thiadiazin-2-yl]amine Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114763&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3585427 252664240 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238707 Fc1cccc(F)c1CN=Nc1ccccn1 InChI=1S/C12H9F2N3/c13-10-4-3-5-11(14)9(10)8-16-17-12-6-1-2-7-15-12/h1-7H,8H2 MKJUUPZBKSWHRY-UHFFFAOYSA-N 114764 MLS001005311::N-[(E)-(2,6-difluorophenyl)methylideneamino]-2-pyridinamine::N-[(E)-(2,6-difluorophenyl)methylideneamino]pyridin-2-amine::N-[(E)-[2,6-bis(fluoranyl)phenyl]methylideneamino]pyridin-2-amine::SMR000348604::[(E)-(2,6-difluorobenzylidene)amino]-(2-pyridyl)amine::cid_9640541 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114764&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899731 252664241 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238708 [O-][N+](=O)c1ccccc1-c1ccc(o1)C(=S)N1CCCC1 InChI=1S/C15H14N2O3S/c18-17(19)12-6-2-1-5-11(12)13-7-8-14(20-13)15(21)16-9-3-4-10-16/h1-2,5-8H,3-4,9-10H2 LNTMERMVWRMWOQ-UHFFFAOYSA-N 83925 MLS001005319::SMR000348684::[5-(2-nitrophenyl)-2-furanyl]-(1-pyrrolidinyl)methanethione::[5-(2-nitrophenyl)-2-furyl]-pyrrolidino-methanethione::[5-(2-nitrophenyl)furan-2-yl]-pyrrolidin-1-yl-methanethione::[5-(2-nitrophenyl)furan-2-yl]-pyrrolidin-1-ylmethanethione::cid_1540853 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83925&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1540853 252659096 ZINC01471359 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238709 COc1ccc(cc1)C(=O)\N=c1/sc2ccccc2n1C InChI=1S/C16H14N2O2S/c1-18-13-5-3-4-6-14(13)21-16(18)17-15(19)11-7-9-12(20-2)10-8-11/h3-10H,1-2H3/b17-16- MRSIYRACITXUGL-MSUUIHNZSA-N 49954 4-methoxy-N-(3-methyl-1,3-benzothiazol-2-ylidene)benzamide::MLS001007199::SMR000352474::cid_2318917 Oxysterols receptor LXR-beta 67481 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49954&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2318917 252630228 ZINC12512390 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238710 Fc1cccc(Cl)c1CN=Nc1ccccn1 InChI=1S/C12H9ClFN3/c13-10-4-3-5-11(14)9(10)8-16-17-12-6-1-2-7-15-12/h1-7H,8H2 SEXWNQJEZDYAJP-UHFFFAOYSA-N 114765 MLS001005565::N-[(E)-(2-chloranyl-6-fluoranyl-phenyl)methylideneamino]pyridin-2-amine::N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]-2-pyridinamine::N-[(E)-(2-chloro-6-fluorophenyl)methylideneamino]pyridin-2-amine::SMR000348839::[(E)-(2-chloro-6-fluoro-benzylidene)amino]-(2-pyridyl)amine::cid_9612911 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114765&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899732 252664242 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238711 N(N=Cc1ccccn1)C1=Nc2cccc3cccc1c23 InChI=1S/C17H12N4/c1-2-10-18-13(7-1)11-19-21-17-14-8-3-5-12-6-4-9-15(20-17)16(12)14/h1-11H,(H,20,21) DNFFPBKFHTVMKK-UHFFFAOYSA-N 49958 MLS001003771::N-(2-pyridinylmethylideneamino)-2-benzo[cd]indolamine::N-(pyridin-2-ylmethylideneamino)benzo[cd]indol-2-amine::SMR000347601::benzo[cd]indol-2-yl-(2-pyridylmethyleneamino)amine::benzo[cd]indol-2-yl-[(E)-2-pyridylmethyleneamino]amine::cid_2315102 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49958&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6899636 252630232 ZINC06455520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238712 Cc1csc(SCC(=O)Nc2sccc2C#N)n1 InChI=1S/C11H9N3OS3/c1-7-5-17-11(13-7)18-6-9(15)14-10-8(4-12)2-3-16-10/h2-3,5H,6H2,1H3,(H,14,15) PKGPVTOMEBHOTG-UHFFFAOYSA-N 114766 MLS001004197::N-(3-cyano-2-thienyl)-2-[(4-methylthiazol-2-yl)thio]acetamide::N-(3-cyano-2-thiophenyl)-2-[(4-methyl-2-thiazolyl)thio]acetamide::N-(3-cyanothiophen-2-yl)-2-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]acetamide::N-(3-cyanothiophen-2-yl)-2-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]ethanamide::SMR000377856::cid_2087887 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114766&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2087887 252664243 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238713 Cc1ccc(cc1)\N=N\c1cc(C)ccc1N InChI=1S/C14H15N3/c1-10-3-6-12(7-4-10)16-17-14-9-11(2)5-8-13(14)15/h3-9H,15H2,1-2H3/b17-16+ BBVUAJTZGSWJDD-WUKNDPDISA-N 114767 4-methyl-2-(4-methylphenyl)azoaniline::4-methyl-2-[(4-methylphenyl)diazenyl]aniline::MLS001013357::SMR000385271::[4-methyl-2-(p-tolylazo)phenyl]amine::cid_571869 Oxysterols receptor LXR-beta 67506 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114767&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 571869 252664244 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238714 COc1ccc(-c2csc(n2)-c2ccccc2)c(OC)c1 InChI=1S/C17H15NO2S/c1-19-13-8-9-14(16(10-13)20-2)15-11-21-17(18-15)12-6-4-3-5-7-12/h3-11H,1-2H3 UYAPYZIXBMPWKE-UHFFFAOYSA-N 49975 4-(2,4-dimethoxyphenyl)-2-phenyl-1,3-thiazole::4-(2,4-dimethoxyphenyl)-2-phenyl-thiazole::4-(2,4-dimethoxyphenyl)-2-phenylthiazole::MLS000807208::SMR000376343::cid_2441960 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49975&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2441960 252630249 ZINC03326337 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238715 Clc1nc2sccn2c1C(=O)N(C(=O)c1c(Cl)nc2sccn12)c1ccc(Cl)cn1 InChI=1S/C17H7Cl3N6O2S2/c18-8-1-2-9(21-7-8)26(14(27)10-12(19)22-16-24(10)3-5-29-16)15(28)11-13(20)23-17-25(11)4-6-30-17/h1-7H QIKABAMNVDMLJH-UHFFFAOYSA-N 114768 6-chloranyl-N-(6-chloranylimidazo[2,1-b][1,3]thiazol-5-yl)carbonyl-N-(5-chloranylpyridin-2-yl)imidazo[2,1-b][1,3]thiazole-5-carboxamide::6-chloro-N-(6-chloroimidazo[2,1-b][1,3]thiazole-5-carbonyl)-N-(5-chloropyridin-2-yl)imidazo[2,1-b][1,3]thiazole-5-carboxamide::6-chloro-N-(6-chloroimidazo[2,1-b]thiazole-5-carbonyl)-N-(5-chloro-2-pyridyl)imidazo[2,1-b]thiazole-5-carboxamide::6-chloro-N-[(6-chloro-5-imidazo[2,1-b]thiazolyl)-oxomethyl]-N-(5-chloro-2-pyridinyl)-5-imidazo[2,1-b]thiazolecarboxamide::MLS000879883::SMR000065735::cid_2316653 Oxysterols receptor LXR-beta 67540 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114768&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2316653 252664245 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238716 CN=c1scc(-c2ccccc2F)n1N=Cc1ccc(O)c(O)c1O InChI=1S/C17H14FN3O3S/c1-19-17-21(13(9-25-17)11-4-2-3-5-12(11)18)20-8-10-6-7-14(22)16(24)15(10)23/h2-9,22-24H,1H3 DVLVRLUCOKAWQB-UHFFFAOYSA-N 34982 (4E)-4-[[[4-(2-fluorophenyl)-2-methylimino-1,3-thiazol-3-yl]amino]methylidene]-2,3-bis(oxidanyl)cyclohexa-2,5-dien-1-one::(4E)-4-[[[4-(2-fluorophenyl)-2-methylimino-1,3-thiazol-3-yl]amino]methylidene]-2,3-dihydroxycyclohexa-2,5-dien-1-one::(4E)-4-[[[4-(2-fluorophenyl)-2-methylimino-3-thiazolyl]amino]methylidene]-2,3-dihydroxy-1-cyclohexa-2,5-dienone::(4E)-4-[[[4-(2-fluorophenyl)-2-methylimino-4-thiazolin-3-yl]amino]methylene]-2,3-dihydroxy-cyclohexa-2,5-dien-1-one::MLS000774515::SMR000372035::cid_5894545 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34982&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5894545 252617625 ZINC38166859 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238717 CC(=O)Nc1ccc(CN=Nc2nc3ccccc3s2)cc1 InChI=1S/C16H14N4OS/c1-11(21)18-13-8-6-12(7-9-13)10-17-20-16-19-14-4-2-3-5-15(14)22-16/h2-9H,10H2,1H3,(H,18,21) YHPDSGONSNFBIC-UHFFFAOYSA-N 43774 MLS001017252::N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]acetamide::N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]ethanamide::N-[4-[(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide::N-[4-[(E)-(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide::SMR000353528::cid_220697 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43774&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896576 252624450 ZINC31601757 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238718 [O-][N+](=O)c1cccc(c1)-c1nc(no1)-c1ccccn1 InChI=1S/C13H8N4O3/c18-17(19)10-5-3-4-9(8-10)13-15-12(16-20-13)11-6-1-2-7-14-11/h1-8H YYKRPCBJFTUNFZ-UHFFFAOYSA-N 90654 2-[5-(3-Nitro-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine::5-(3-nitrophenyl)-3-(2-pyridinyl)-1,2,4-oxadiazole::5-(3-nitrophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole::5-(3-nitrophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole::MLS001012185::SMR000425198::cid_867096 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=90654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=90654&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 867096 252662209 ZINC00430479 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238719 Cn1c2ccccc2n(CC(=O)c2ccccc2)c1=N InChI=1S/C16H15N3O/c1-18-13-9-5-6-10-14(13)19(16(18)17)11-15(20)12-7-3-2-4-8-12/h2-10,17H,11H2,1H3 GCNZGZROTNFCTM-UHFFFAOYSA-N 114770 2-(2-Imino-3-methyl-2,3-dihydro-benzoimidazol-1-yl)-1-phenyl-ethanone::2-(2-azanylidene-3-methyl-benzimidazol-1-yl)-1-phenyl-ethanone;hydrobromide::2-(2-imino-3-methyl-1-benzimidazolyl)-1-phenylethanone;hydrobromide::2-(2-imino-3-methyl-benzimidazol-1-yl)-1-phenyl-ethanone;hydrobromide::2-(2-imino-3-methylbenzimidazol-1-yl)-1-phenylethanone;hydrobromide::MLS001049377::SMR000427359::cid_2852336 Oxysterols receptor LXR-beta 67460 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114770&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 594732 252664246 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238720 Nc1c2CCc3ccccc3-c2nc2sc3CCCCc3c12 InChI=1S/C19H18N2S/c20-17-14-10-9-11-5-1-2-6-12(11)18(14)21-19-16(17)13-7-3-4-8-15(13)22-19/h1-2,5-6H,3-4,7-10H2,(H2,20,21) QDXAWXXELADXKG-UHFFFAOYSA-N 114771 5,6,8,9,10,11-Hexahydro-12-thia-13-aza-indeno[1,2-b]phenanthren-7-ylamine::MLS000768861::SMR000432160::cid_828292 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114771&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 828292 242053906 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238721 Oc1c(N=Nc2ccccc2)sc2ccccc12 InChI=1S/C14H10N2OS/c17-13-11-8-4-5-9-12(11)18-14(13)16-15-10-6-2-1-3-7-10/h1-9,17H NINPOLKSNFCLDI-UHFFFAOYSA-N 114772 (2Z)-2-(phenylhydrazinylidene)-1-benzothiophen-3-one::(2Z)-2-(phenylhydrazono)benzothiophen-3-one::2-(Phenyl-hydrazono)-benzo[b]thiophen-3-one::MLS000777106::SMR000413502::cid_5419037 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114772&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5419037 252664247 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238722 c1ccc(nc1)-c1nnc(s1)-c1ccccn1 InChI=1S/C12H8N4S/c1-3-7-13-9(5-1)11-15-16-12(17-11)10-6-2-4-8-14-10/h1-8H BGORQFGAWSNEBU-UHFFFAOYSA-N 114773 2,5-bis(2-pyridinyl)-1,3,4-thiadiazole::2,5-bis(2-pyridyl)-1,3,4-thiadiazole::2,5-dipyridin-2-yl-1,3,4-thiadiazole::MLS000737262::SMR000444347::cid_267294 Oxysterols receptor LXR-beta 67499 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114773&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 267294 252664248 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238723 Cc1ccc(cc1\N=N\c1cc(C)c(N)cc1N)\N=N\c1cc(C)c(N)cc1N InChI=1S/C21H24N8/c1-11-4-5-14(26-28-20-6-12(2)15(22)9-17(20)24)8-19(11)27-29-21-7-13(3)16(23)10-18(21)25/h4-10H,22-25H2,1-3H3/b28-26+,29-27+ SOJKLCSQJMPLCK-TUUFZWAFSA-N 51880 4-[3-(2,4-diamino-5-methylphenyl)azo-4-methylphenyl]azo-6-methylbenzene-1,3-diamine::4-[[3-[(2,4-diamino-5-methylphenyl)diazenyl]-4-methylphenyl]diazenyl]-6-methylbenzene-1,3-diamine::4-[[3-[[2,4-bis(azanyl)-5-methyl-phenyl]diazenyl]-4-methyl-phenyl]diazenyl]-6-methyl-benzene-1,3-diamine::MLS000736629::SMR000528226::Vesuvine::[5-amino-2-[3-(2,4-diamino-5-methyl-phenyl)azo-4-methyl-phenyl]azo-4-methyl-phenyl]amine::cid_24674 Oxysterols receptor LXR-beta 67521 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51880&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24674 252632042 ZINC01400944 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238724 COc1ccc(cc1)C(=O)CC=Nc1cc(C)ccn1 InChI=1S/C16H16N2O2/c1-12-7-9-17-16(11-12)18-10-8-15(19)13-3-5-14(20-2)6-4-13/h3-7,9-11H,8H2,1-2H3 NTLCODYJXMHWHY-UHFFFAOYSA-N 95967 (E)-1-(4-Methoxy-phenyl)-3-(4-methyl-pyridin-2-ylamino)-propenone::(E)-1-(4-methoxyphenyl)-3-[(4-methyl-2-pyridinyl)amino]-2-propen-1-one::(E)-1-(4-methoxyphenyl)-3-[(4-methyl-2-pyridyl)amino]prop-2-en-1-one::(E)-1-(4-methoxyphenyl)-3-[(4-methylpyridin-2-yl)amino]prop-2-en-1-one::MLS001043227::SMR000425297::cid_1927485 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95967&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899582 164037211 ZINC00286200 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238725 NC(SCC=C)=NN=Cc1c(O)ccc2ccccc12 InChI=1S/C15H15N3OS/c1-2-9-20-15(16)18-17-10-13-12-6-4-3-5-11(12)7-8-14(13)19/h2-8,10,19H,1,9H2,(H2,16,18) IXIGRVITDDGCKN-UHFFFAOYSA-N 114549 2-allyl-3-[[(Z)-(2-keto-1-naphthylidene)methyl]amino]isothiourea::MLS000777469::N'-[[(Z)-(2-oxo-1-naphthalenylidene)methyl]amino]carbamimidothioic acid prop-2-enyl ester::SMR000413863::cid_56642948::prop-2-enyl N'-[[(Z)-(2-oxidanylidenenaphthalen-1-ylidene)methyl]amino]carbamimidothioate::prop-2-enyl N'-[[(Z)-(2-oxonaphthalen-1-ylidene)methyl]amino]carbamimidothioate Oxysterols receptor LXR-beta 67473 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114549&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 56642948 252664048 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238726 Cc1ccc(NN=C(C#N)C(=N)N2CCCCC2)cc1 InChI=1S/C15H19N5/c1-12-5-7-13(8-6-12)18-19-14(11-16)15(17)20-9-3-2-4-10-20/h5-8,17-18H,2-4,9-10H2,1H3 SIEYPLBBVFUPJU-UHFFFAOYSA-N 114775 (1E)-2-imino-N-(4-methylanilino)-2-piperidin-1-ylethanimidoyl cyanide::(2E)-3-azanylidene-2-[(4-methylphenyl)hydrazinylidene]-3-piperidin-1-yl-propanenitrile::(2E)-3-imino-2-[(4-methylphenyl)hydrazinylidene]-3-(1-piperidinyl)propanenitrile::(2E)-3-imino-3-piperidino-2-(p-tolylhydrazono)propionitrile::3-Imino-3-piperidin-1-yl-2-(p-tolyl-hydrazono)-propionitrile::MLS000779899::SMR000420079::cid_6401658 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6401658 252664249 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238727 Cc1cc(C=C2SC(S)=NC2=O)c(C)n1-c1ccccc1 InChI=1S/C16H14N2OS2/c1-10-8-12(9-14-15(19)17-16(20)21-14)11(2)18(10)13-6-4-3-5-7-13/h3-9H,1-2H3,(H,17,19,20) HGDVAXSIRLADHC-UHFFFAOYSA-N 114776 (5Z)-5-[(2,5-dimethyl-1-phenyl-3-pyrrolyl)methylidene]-2-sulfanylidene-4-thiazolidinone::(5Z)-5-[(2,5-dimethyl-1-phenyl-pyrrol-3-yl)methylene]-2-thioxo-thiazolidin-4-one::(5Z)-5-[(2,5-dimethyl-1-phenyl-pyrrol-3-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one::(5Z)-5-[(2,5-dimethyl-1-phenylpyrrol-3-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one::5-[1-(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one::MLS000779590::SMR000419773::cid_1201959 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114776&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1201959 252664250 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238728 OC(=O)c1cccc(NC(=O)C(=O)Nc2ccc(cc2)[N+]([O-])=O)c1 InChI=1S/C15H11N3O6/c19-13(16-10-4-6-12(7-5-10)18(23)24)14(20)17-11-3-1-2-9(8-11)15(21)22/h1-8H,(H,16,19)(H,17,20)(H,21,22) WADXPDDPAAFLRR-UHFFFAOYSA-N 114777 3-[(4-Nitro-phenylaminooxalyl)-amino]-benzoic acid::3-[[2-(4-nitroanilino)-1,2-dioxoethyl]amino]benzoic acid::3-[[2-(4-nitroanilino)-2-oxoacetyl]amino]benzoic acid::3-[[2-[(4-nitrophenyl)amino]-2-oxidanylidene-ethanoyl]amino]benzoic acid::3-[[2-keto-2-(4-nitroanilino)acetyl]amino]benzoic acid::MLS000777654::SMR000414048::cid_4617342 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114777&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4617342 252664251 C02125 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238729 c1cc(sc1-c1ccccn1)-c1ccccn1 InChI=1S/C14H10N2S/c1-3-9-15-11(5-1)13-7-8-14(17-13)12-6-2-4-10-16-12/h1-10H NIJMGWPTVYSTCQ-UHFFFAOYSA-N 114778 2-(5-pyridin-2-ylthiophen-2-yl)pyridine::2-[5-(2-pyridinyl)-2-thiophenyl]pyridine::2-[5-(2-pyridyl)-2-thienyl]pyridine::MLS000851103::SMR000457346::cid_2801704 Oxysterols receptor LXR-beta 67520 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114778&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2801704 252664252 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238730 C(N=Nc1ccccc1)c1nc2ccccc2s1 InChI=1S/C14H11N3S/c1-2-6-11(7-3-1)17-15-10-14-16-12-8-4-5-9-13(12)18-14/h1-9H,10H2 KLHDBNWZDLVHLJ-UHFFFAOYSA-N 76599 (1,3-benzothiazol-2-ylmethyleneamino)-phenyl-amine::1,3-benzothiazole-2-carbaldehyde 2-phenylhydrazone::MLS000860196::N-(1,3-benzothiazol-2-ylmethylideneamino)aniline::SMR000460975::[(E)-1,3-benzothiazol-2-ylmethyleneamino]-phenyl-amine::cid_2740166 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76599&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91898183 252653777 ZINC15924191 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238731 C1C2CCc3ccccc3C2=NN1c1ccccc1 InChI=1S/C17H16N2/c1-2-7-15(8-3-1)19-12-14-11-10-13-6-4-5-9-16(13)17(14)18-19/h1-9,14H,10-12H2 AZVVFDRHHIKULU-UHFFFAOYSA-N 72741 2-phenyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole::2-phenyl-3,3a,4,5-tetrahydrobenz[g]indazole::2-phenyl-3,3a,4,5-tetrahydrobenzo[g]indazole::MLS000860761::SMR000459545::cid_619222 Oxysterols receptor LXR-beta 67495 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 619222 252649994 ZINC04362106 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238732 CCCC#Cc1ccc-2c(COc3n-2nc2ccccc32)c1 InChI=1S/C19H16N2O/c1-2-3-4-7-14-10-11-18-15(12-14)13-22-19-16-8-5-6-9-17(16)20-21(18)19/h5-6,8-12H,2-3,13H2,1H3 NARJKBPPRTYBJX-UHFFFAOYSA-N 114780 3-pent-1-ynyl-5H-indazolo[2,3-a][3,1]benzoxazine::MLS000911992::SMR000471334::cid_23640972 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114780&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23640972 252664253 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238733 c1ccc(cc1)-c1cnc(nn1)-c1ccccc1 InChI=1S/C15H11N3/c1-3-7-12(8-4-1)14-11-16-15(18-17-14)13-9-5-2-6-10-13/h1-11H LRGATPZENUYRBP-UHFFFAOYSA-N 93859 3,6-diphenyl-1,2,4-triazine::MLS000911953::SMR000471597::cid_6617829 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93859&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6617829 164035103 ZINC13118821 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238734 Cc1ccccc1NNC1=c2ccccc2=NC1=O InChI=1S/C15H13N3O/c1-10-6-2-4-8-12(10)17-18-14-11-7-3-5-9-13(11)16-15(14)19/h2-9,17H,1H3,(H,16,18,19) GNENHQKUQDNVBG-UHFFFAOYSA-N 114781 1H-indole-2,3-dione 3-[(2-methylphenyl)hydrazone]::3-[(2-methylphenyl)hydrazo]-2-indolone::3-[2-(2-methylphenyl)hydrazinyl]indol-2-one::3-[N'-(o-tolyl)hydrazino]indol-2-one::MLS001178907::SMR000475997::cid_5381405 Oxysterols receptor LXR-beta 67462 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114781&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5381405 252664254 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238735 CC(=O)n1nc(cc1-c1ccccc1)-c1ccccc1 InChI=1S/C17H14N2O/c1-13(20)19-17(15-10-6-3-7-11-15)12-16(18-19)14-8-4-2-5-9-14/h2-12H,1H3 LEZLHOKJTQXBOW-UHFFFAOYSA-N 114782 1-(3,5-diphenyl-1-pyrazolyl)ethanone::1-(3,5-diphenylpyrazol-1-yl)ethanone::1-acetyl-3,5-diphenyl-1H-pyrazole::MLS001178338::SMR000476011::cid_828167 Oxysterols receptor LXR-beta 67460 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114782&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 828167 252664255 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238737 c1cc2cccccc2c1\N=N\c1ccccc1 InChI=1S/C16H12N2/c1-3-7-13-11-12-16(15(13)10-6-1)18-17-14-8-4-2-5-9-14/h1-12H/b18-17+ FILMYAMPKWRDQD-ISLYRVAYSA-N 76615 1-(1-azulenyl)-2-phenyldiazene::1-azulenyl(phenyl)diazene::MLS001180429::SMR000476304::azulen-1-yl(phenyl)diazene::cid_3666713 Oxysterols receptor LXR-beta 67462 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76615&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3666713 252653792 ZINC18101416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238738 Cc1ccc(O)c(c1)-c1cc(no1)-c1ccc(F)cc1 InChI=1S/C16H12FNO2/c1-10-2-7-15(19)13(8-10)16-9-14(18-20-16)11-3-5-12(17)6-4-11/h2-9,19H,1H3 MZLONDGTDQSWHL-UHFFFAOYSA-N 114784 (6Z)-6-[3-(4-fluorophenyl)-2H-1,2-oxazol-5-ylidene]-4-methyl-cyclohexa-2,4-dien-1-one::(6Z)-6-[3-(4-fluorophenyl)-2H-1,2-oxazol-5-ylidene]-4-methylcyclohexa-2,4-dien-1-one::(6Z)-6-[3-(4-fluorophenyl)-2H-isoxazol-5-ylidene]-4-methyl-1-cyclohexa-2,4-dienone::(6Z)-6-[3-(4-fluorophenyl)-3-isoxazolin-5-ylidene]-4-methyl-cyclohexa-2,4-dien-1-one::2-[3-(4-fluorophenyl)-5-isoxazolyl]-4-methylphenol::MLS001163487::SMR000496767::cid_5726794 Oxysterols receptor LXR-beta 67485 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114784&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5726794 252664257 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238739 CC(C)N(CCO)Cc1nc(oc1C)-c1ccc(cc1)-c1ccccc1 InChI=1S/C22H26N2O2/c1-16(2)24(13-14-25)15-21-17(3)26-22(23-21)20-11-9-19(10-12-20)18-7-5-4-6-8-18/h4-12,16,25H,13-15H2,1-3H3 CHVWMSPMCIIYOG-UHFFFAOYSA-N 114785 2-[[(2-biphenyl-4-yl-5-methyl-1,3-oxazol-4-yl)methyl](isopropyl)amino]ethanol::2-[[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]methyl-propan-2-yl-amino]ethanol::2-[[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]methyl-propan-2-ylamino]ethanol::2-[[5-methyl-2-(4-phenylphenyl)-4-oxazolyl]methyl-propan-2-ylamino]ethanol::2-[isopropyl-[[5-methyl-2-(4-phenylphenyl)oxazol-4-yl]methyl]amino]ethanol::MLS000971245::SMR000495702::cid_23723216 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114785&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23723216 252664258 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238740 Cc1ccsc1C=NN=Cc1sccc1C InChI=1S/C12H12N2S2/c1-9-3-5-15-11(9)7-13-14-8-12-10(2)4-6-16-12/h3-8H,1-2H3 AQSGGOLDOQGOAO-UHFFFAOYSA-N 114786 (E)-(3-methyl-2-thienyl)methylene-[(E)-(3-methyl-2-thienyl)methyleneamino]amine::(E)-1-(3-methyl-2-thiophenyl)-N-[(E)-(3-methyl-2-thiophenyl)methylideneamino]methanimine::(E)-1-(3-methylthiophen-2-yl)-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]methanimine::3-methyl-2-thiophenecarbaldehyde [(3-methyl-2-thienyl)methylene]hydrazone::MLS001008496::SMR000495861::cid_6895732 Oxysterols receptor LXR-beta 67540 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114786&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6895732 252664259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238741 Cc1csc(N=NCc2ccccc2F)n1 InChI=1S/C11H10FN3S/c1-8-7-16-11(14-8)15-13-6-9-4-2-3-5-10(9)12/h2-5,7H,6H2,1H3 HNRRLXBTFVYPFZ-UHFFFAOYSA-N 114787 2-fluorobenzaldehyde (4-methyl-1,3-thiazol-2-yl)hydrazone::MLS001001393::N-[(E)-(2-fluorophenyl)methylideneamino]-4-methyl-1,3-thiazol-2-amine::N-[(E)-(2-fluorophenyl)methylideneamino]-4-methyl-2-thiazolamine::SMR000496928::[(E)-(2-fluorobenzylidene)amino]-(4-methylthiazol-2-yl)amine::cid_5348649 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114787&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899734 252664260 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238742 Cn1c2ccccc2n(CC(=O)c2ccc(Br)cc2)c1=N InChI=1S/C16H14BrN3O/c1-19-13-4-2-3-5-14(13)20(16(19)18)10-15(21)11-6-8-12(17)9-7-11/h2-9,18H,10H2,1H3 PUVXHJNHJICBBO-UHFFFAOYSA-N 84297 1-(4-bromophenyl)-2-(2-imino-3-methyl-1-benzimidazolyl)ethanone;hydrobromide::1-(4-bromophenyl)-2-(2-imino-3-methyl-2,3-dihydro-1H-benzimidazol-1-yl)ethanone::1-(4-bromophenyl)-2-(2-imino-3-methyl-benzimidazol-1-yl)ethanone;hydrobromide::1-(4-bromophenyl)-2-(2-imino-3-methylbenzimidazol-1-yl)ethanone;hydrobromide::2-(2-azanylidene-3-methyl-benzimidazol-1-yl)-1-(4-bromophenyl)ethanone;hydrobromide::CHEMBL255837::MLS001179161::SMR000476138::cid_2851497 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84297&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 594995 252659423 CHEMBL255837 ZINC00087629 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238744 O=c1oc2ccccc2cc1-c1nc2ccccc2[nH]1 InChI=1S/C16H10N2O2/c19-16-11(9-10-5-1-4-8-14(10)20-16)15-17-12-6-2-3-7-13(12)18-15/h1-9H,(H,17,18) YRFHFTBLQARMCG-UHFFFAOYSA-N 114789 3-(1H-Benzoimidazol-2-yl)-chromen-2-one::3-(1H-benzimidazol-2-yl)-1-benzopyran-2-one::3-(1H-benzimidazol-2-yl)chromen-2-one::3-(1H-benzimidazol-2-yl)coumarin::MLS001205135::SMR000515825::cid_732122 Oxysterols receptor LXR-beta 67476 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114789&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 732122 252664262 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238745 Cc1cc(C)nc(Nc2nc(cs2)-c2ccccc2)n1 InChI=1S/C15H14N4S/c1-10-8-11(2)17-14(16-10)19-15-18-13(9-20-15)12-6-4-3-5-7-12/h3-9H,1-2H3,(H,16,17,18,19) MEYHVGRXGIMJNL-UHFFFAOYSA-N 76632 (4,6-dimethylpyrimidin-2-yl)-(4-phenylthiazol-2-yl)amine::MLS001183973::N-(4,6-dimethyl-2-pyrimidinyl)-4-phenyl-2-thiazolamine::N-(4,6-dimethylpyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-amine::SMR000502662::cid_2354999 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76632&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2354999 252653809 ZINC03237231 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238746 Cc1ccc(-c2cc([nH]n2)-c2ccc(F)cc2)c(O)c1 InChI=1S/C16H13FN2O/c1-10-2-7-13(16(20)8-10)15-9-14(18-19-15)11-3-5-12(17)6-4-11/h2-9,20H,1H3,(H,18,19) ZRVVXIGRKYZYGG-UHFFFAOYSA-N 114790 (6Z)-6-[5-(4-fluorophenyl)-1,2-dihydropyrazol-3-ylidene]-3-methyl-1-cyclohexa-2,4-dienone::(6Z)-6-[5-(4-fluorophenyl)-1,2-dihydropyrazol-3-ylidene]-3-methyl-cyclohexa-2,4-dien-1-one::(6Z)-6-[5-(4-fluorophenyl)-1,2-dihydropyrazol-3-ylidene]-3-methylcyclohexa-2,4-dien-1-one::(6Z)-6-[5-(4-fluorophenyl)-3-pyrazolin-3-ylidene]-3-methyl-cyclohexa-2,4-dien-1-one::2-[5-(4-Fluoro-phenyl)-1H-pyrazol-3-yl]-5-methyl-phenol::MLS001207693::SMR000516051::cid_5405903 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114790&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5405903 252664263 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238747 CC([NH+]=Nc1ccccc1[N+]([O-])=O)[c-]1ccccc1=O InChI=1S/C14H12N3O3/c1-10(11-6-2-5-9-14(11)18)15-16-12-7-3-4-8-13(12)17(19)20/h2-10H,1H3/q-1/p+1 NSZDFXQMJPDXSP-UHFFFAOYSA-O 114791 (6E)-6-[1-[(2-nitrophenyl)hydrazo]ethylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[1-[2-(2-nitrophenyl)hydrazinyl]ethylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[1-[N'-(2-nitrophenyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one::2-{1-[(2-Nitro-phenyl)-hydrazono]-ethyl}-phenol::MLS001209980::SMR000514599::cid_5758075 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114791&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899735 252664264 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238748 Cc1ccc(Nc2nc(cs2)-c2ccccc2)nc1 InChI=1S/C15H13N3S/c1-11-7-8-14(16-9-11)18-15-17-13(10-19-15)12-5-3-2-4-6-12/h2-10H,1H3,(H,16,17,18) QIQMGBPCRJGQLU-UHFFFAOYSA-N 114792 (5-Methyl-pyridin-2-yl)-(4-phenyl-thiazol-2-yl)-amine::(5-methyl-2-pyridyl)-(4-phenylthiazol-2-yl)amine::MLS001206596::N-(5-methyl-2-pyridinyl)-4-phenyl-2-thiazolamine::N-(5-methylpyridin-2-yl)-4-phenyl-1,3-thiazol-2-amine::SMR000524294::cid_972993 Oxysterols receptor LXR-beta 67481 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114792&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 972993 252664265 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238749 NC(=O)c1c(NC(=O)c2ccc(F)cc2)sc2CCCc12 InChI=1S/C15H13FN2O2S/c16-9-6-4-8(5-7-9)14(20)18-15-12(13(17)19)10-2-1-3-11(10)21-15/h4-7H,1-3H2,(H2,17,19)(H,18,20) APSCBHPLIJURCC-UHFFFAOYSA-N 75652 2-(4-Fluoro-benzoylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid amide::2-[(4-fluorobenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide::2-[(4-fluorophenyl)carbonylamino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide::2-[[(4-fluorophenyl)-oxomethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide::MLS001201422::SMR000523557::cid_675164 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75652&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 675164 252652855 ZINC00037917 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238750 NC(=O)c1c(NC(=O)c2ccccc2)sc2CCCCc12 InChI=1S/C16H16N2O2S/c17-14(19)13-11-8-4-5-9-12(11)21-16(13)18-15(20)10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9H2,(H2,17,19)(H,18,20) ZYIMILUMMMUVLQ-UHFFFAOYSA-N 50185089 2-benzamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide::CHEMBL210266::cid_678544 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185089&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 678544 104069330 CHEMBL210266 ZINC00042568 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238751 NC(=O)c1c(NC(=O)c2ccccc2)sc2CCCc12 InChI=1S/C15H14N2O2S/c16-13(18)12-10-7-4-8-11(10)20-15(12)17-14(19)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H2,16,18)(H,17,19) WUXSRILVTCNVAY-UHFFFAOYSA-N 76651 2-Benzoylamino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid amide::2-benzamido-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide::MLS001206402::SMR000523552::cid_712900 Oxysterols receptor LXR-beta 67498 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76651&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 712900 252653828 ZINC00106317 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238752 N(c1nc(cs1)-c1ccccc1)c1ccccn1 InChI=1S/C14H11N3S/c1-2-6-11(7-3-1)12-10-18-14(16-12)17-13-8-4-5-9-15-13/h1-10H,(H,15,16,17) WSTKLVLYBZVDNA-UHFFFAOYSA-N 93875 (4-Phenyl-thiazol-2-yl)-pyridin-2-yl-amine::(4-phenylthiazol-2-yl)-(2-pyridyl)amine::4-phenyl-N-(2-pyridinyl)-2-thiazolamine::4-phenyl-N-pyridin-2-yl-1,3-thiazol-2-amine::MLS001206908::SMR000524292::cid_750531 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93875&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 750531 164035119 ZINC00199190 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238753 Cc1cccc(Nc2nc(cs2)-c2ccccc2)n1 InChI=1S/C15H13N3S/c1-11-6-5-9-14(16-11)18-15-17-13(10-19-15)12-7-3-2-4-8-12/h2-10H,1H3,(H,16,17,18) LSBCOVVXPPHMML-UHFFFAOYSA-N 114793 (6-Methyl-pyridin-2-yl)-(4-phenyl-thiazol-2-yl)-amine::(6-methyl-2-pyridyl)-(4-phenylthiazol-2-yl)amine::MLS001206894::N-(6-methyl-2-pyridinyl)-4-phenyl-2-thiazolamine::N-(6-methylpyridin-2-yl)-4-phenyl-1,3-thiazol-2-amine::SMR000524295::cid_972914 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114793&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 972914 252664266 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238754 [O-][N+](=O)c1cc(ccc1Cl)C(=O)Nc1ccc(Nc2ccccc2)cc1 InChI=1S/C19H14ClN3O3/c20-17-11-6-13(12-18(17)23(25)26)19(24)22-16-9-7-15(8-10-16)21-14-4-2-1-3-5-14/h1-12,21H,(H,22,24) UNEYAHULDSQRNV-UHFFFAOYSA-N 77836 4-chloranyl-3-nitro-N-(4-phenylazanylphenyl)benzamide::MLS001001419::N-(4-anilinophenyl)-4-chloro-3-nitro-benzamide::N-(4-anilinophenyl)-4-chloro-3-nitrobenzamide::SMR000497019::cid_3824991 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77836&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3824991 252654710 ZINC13126729 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238755 CCc1ccc(cc1)-n1nc2cc(C)c(N)cc2n1 InChI=1S/C15H16N4/c1-3-11-4-6-12(7-5-11)19-17-14-8-10(2)13(16)9-15(14)18-19/h4-9H,3,16H2,1-2H3 SNNHVUDPIOPIPM-UHFFFAOYSA-N 96061 2-(4-Ethyl-phenyl)-6-methyl-2H-benzotriazol-5-ylamine::2-(4-ethylphenyl)-6-methyl-5-benzotriazolamine::2-(4-ethylphenyl)-6-methyl-benzotriazol-5-amine::2-(4-ethylphenyl)-6-methylbenzotriazol-5-amine::MLS001211694::SMR000518909::[2-(4-ethylphenyl)-6-methyl-benzotriazol-5-yl]amine::cid_783935 Oxysterols receptor LXR-beta 67500 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 783935 164037305 ZINC00279698 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238756 Cc1[nH]n(C(N)=S)c(=O)c1N=Nc1ccc(Br)cc1 InChI=1S/C11H10BrN5OS/c1-6-9(10(18)17(16-6)11(13)19)15-14-8-4-2-7(12)3-5-8/h2-5,16H,1H3,(H2,13,19) KMUKJMGGGCHKSR-UHFFFAOYSA-N 114794 (4E)-4-[(4-bromophenyl)hydrazono]-5-keto-3-methyl-2-pyrazoline-1-carbothioamide::4-(4-Bromo-phenylazo)-3-methyl-5-oxo-4,5-dihydro-pyrazole-1-carbothioic acid amide::4-(4-bromophenyl)azo-3-methyl-5-oxo-4H-pyrazole-1-carbothioamide::4-(4-bromophenyl)azo-5-keto-3-methyl-2-pyrazoline-1-carbothioamide::4-[(4-bromophenyl)diazenyl]-3-methyl-5-oxidanylidene-4H-pyrazole-1-carbothioamide::4-[(4-bromophenyl)diazenyl]-3-methyl-5-oxo-4H-pyrazole-1-carbothioamide::MLS001210117::SMR000514003::cid_3106491 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114794&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5800217 252664267 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238757 Cc1cc2ncc(nc2cc1C)-c1cccs1 InChI=1S/C14H12N2S/c1-9-6-11-12(7-10(9)2)16-13(8-15-11)14-4-3-5-17-14/h3-8H,1-2H3 GXAYHHPSLBZYPW-UHFFFAOYSA-N 114795 6,7-dimethyl-2-(2-thienyl)quinoxaline::6,7-dimethyl-2-thiophen-2-yl-quinoxaline::6,7-dimethyl-2-thiophen-2-ylquinoxaline::MLS001173390::SMR000538991::cid_677565 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114795&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 677565 252664268 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238758 Cc1nn(-c2ccc(Br)cc2)c(=O)c2ccccc12 InChI=1S/C15H11BrN2O/c1-10-13-4-2-3-5-14(13)15(19)18(17-10)12-8-6-11(16)7-9-12/h2-9H,1H3 XQMYCQQCDKDZGI-UHFFFAOYSA-N 114796 2-(4-bromophenyl)-4-methyl-1(2H)-phthalazinone::2-(4-bromophenyl)-4-methyl-1-phthalazinone::2-(4-bromophenyl)-4-methyl-phthalazin-1-one::2-(4-bromophenyl)-4-methylphthalazin-1-one::MLS001166289::SMR000549903::cid_755477 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114796&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 755477 252664269 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238759 Cc1ccccc1C(=O)ON=C(N)c1ccccc1 InChI=1S/C15H14N2O2/c1-11-7-5-6-10-13(11)15(18)19-17-14(16)12-8-3-2-4-9-12/h2-10H,1H3,(H2,16,17) RLLIUBHOTCUQQU-UHFFFAOYSA-N 114797 2-methylbenzoic acid [(Z)-[amino(phenyl)methylene]amino] ester::2-methylbenzoic acid [(Z)-[amino(phenyl)methylidene]amino] ester::MLS001196748::N'-[(2-methylbenzoyl)oxy]benzenecarboximidamide::SMR000555889::[(Z)-[amino(phenyl)methylidene]amino] 2-methylbenzoate::[(Z)-[azanyl(phenyl)methylidene]amino] 2-methylbenzoate::cid_5338754 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114797&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5338754 252664270 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238760 COc1ccccc1C(=O)NC(=O)Nc1cccc(Cl)c1 InChI=1S/C15H13ClN2O3/c1-21-13-8-3-2-7-12(13)14(19)18-15(20)17-11-6-4-5-10(16)9-11/h2-9H,1H3,(H2,17,18,19,20) MDFGBWHNTAIZFR-UHFFFAOYSA-N 114798 MLS001195000::N-[(3-chloroanilino)-oxomethyl]-2-methoxybenzamide::N-[(3-chlorophenyl)carbamoyl]-2-methoxy-benzamide::N-[(3-chlorophenyl)carbamoyl]-2-methoxybenzamide::N-{[(3-chlorophenyl)amino]carbonyl}-2-methoxybenzamide::SMR000554536::cid_4035462 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114798&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4035462 252664271 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238761 Cc1ccccc1-c1nc(no1)-c1ccc(Br)o1 InChI=1S/C13H9BrN2O2/c1-8-4-2-3-5-9(8)13-15-12(16-18-13)10-6-7-11(14)17-10/h2-7H,1H3 BSEYQWSYIXNDMN-UHFFFAOYSA-N 76693 3-(5-bromanylfuran-2-yl)-5-(2-methylphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furanyl)-5-(2-methylphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(2-methylphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(o-tolyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-(2-methylphenyl)-1,2,4-oxadiazole::MLS001198212::SMR000559313::cid_715522 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76693&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 715522 252653870 ZINC00112056 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238762 Cc1ccc(cc1C)-c1cnc2ccccc2n1 InChI=1S/C16H14N2/c1-11-7-8-13(9-12(11)2)16-10-17-14-5-3-4-6-15(14)18-16/h3-10H,1-2H3 AJYKLFYVMCSPOL-UHFFFAOYSA-N 114799 2-(3,4-dimethylphenyl)quinoxaline::MLS001197406::SMR000555276::cid_616375 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114799&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 616375 252664272 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238763 Cc1cccc2=C(NNc3ccccc3)C(=O)N=c12 InChI=1S/C15H13N3O/c1-10-6-5-9-12-13(10)16-15(19)14(12)18-17-11-7-3-2-4-8-11/h2-9,17H,1H3,(H,16,18,19) PCYWVEYLUIIDSS-UHFFFAOYSA-N 114800 (3Z)-7-methyl-1H-indole-2,3-dione 3-(phenylhydrazone)::7-methyl-3-(2-phenylhydrazinyl)indol-2-one::7-methyl-3-(N'-phenylhydrazino)indol-2-one::7-methyl-3-(phenylhydrazo)-2-indolone::MLS001194880::SMR000554656::cid_5286407 Oxysterols receptor LXR-beta 67498 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114800&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5286407 252664273 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238764 Fc1ccccc1-c1nc(no1)-c1ccc(Br)o1 InChI=1S/C12H6BrFN2O2/c13-10-6-5-9(17-10)11-15-12(18-16-11)7-3-1-2-4-8(7)14/h1-6H XVPMGLODKHSQKU-UHFFFAOYSA-N 114801 3-(5-bromanylfuran-2-yl)-5-(2-fluorophenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furanyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-(2-fluorophenyl)-1,2,4-oxadiazole::MLS001198373::SMR000559246::cid_1259900 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114801&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1259900 252664274 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238765 Cc1ccc(Nc2nc(cs2)-c2cccnc2)cc1C InChI=1S/C16H15N3S/c1-11-5-6-14(8-12(11)2)18-16-19-15(10-20-16)13-4-3-7-17-9-13/h3-10H,1-2H3,(H,18,19) YYQJMUZUTIQOHV-UHFFFAOYSA-N 76699 (3,4-dimethylphenyl)-[4-(3-pyridyl)thiazol-2-yl]amine::MLS001198635::N-(3,4-dimethylphenyl)-4-(3-pyridinyl)-2-thiazolamine::N-(3,4-dimethylphenyl)-4-pyridin-3-yl-1,3-thiazol-2-amine::SMR000558990::cid_972507 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76699&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 972507 252653876 ZINC00612752 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238766 COc1cccc(NC(=O)n2ncc3c(C)cccc23)c1 InChI=1S/C16H15N3O2/c1-11-5-3-8-15-14(11)10-17-19(15)16(20)18-12-6-4-7-13(9-12)21-2/h3-10H,1-2H3,(H,18,20) MNGMRUVRSZJREZ-UHFFFAOYSA-N 114802 MLS001200210::N-(3-methoxyphenyl)-4-methyl-1-indazolecarboxamide::N-(3-methoxyphenyl)-4-methyl-1H-indazole-1-carboxamide::N-(3-methoxyphenyl)-4-methyl-indazole-1-carboxamide::N-(3-methoxyphenyl)-4-methylindazole-1-carboxamide::SMR000563537::cid_22510376 Oxysterols receptor LXR-beta 67512 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114802&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22510376 252664275 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238767 Fc1cccc(Cl)c1\C=C\c1cnc2ccccc2n1 InChI=1S/C16H10ClFN2/c17-13-4-3-5-14(18)12(13)9-8-11-10-19-15-6-1-2-7-16(15)20-11/h1-10H/b9-8+ CXHPHRDFVBQLLC-CMDGGOBGSA-N 114803 2-[(E)-2-(2-chloranyl-6-fluoranyl-phenyl)ethenyl]quinoxaline::2-[(E)-2-(2-chloro-6-fluoro-phenyl)vinyl]quinoxaline::2-[(E)-2-(2-chloro-6-fluorophenyl)ethenyl]quinoxaline::MLS001181610::SMR000567353::cid_5714039 Oxysterols receptor LXR-beta 67519 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114803&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5714039 252664276 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238768 CN(C)c1ccc(cc1)\N=N\c1ccccc1Br InChI=1S/C14H14BrN3/c1-18(2)12-9-7-11(8-10-12)16-17-14-6-4-3-5-13(14)15/h3-10H,1-2H3/b17-16+ GRUMPROWLYTPSY-WUKNDPDISA-N 75760 4-(2-bromophenyl)azo-N,N-dimethylaniline::4-[(2-bromophenyl)diazenyl]-N,N-dimethyl-aniline::4-[(2-bromophenyl)diazenyl]-N,N-dimethylaniline::MLS001170858::SMR000588378::[4-(2-bromophenyl)azophenyl]-dimethyl-amine::cid_4153146 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4153146 252652961 ZINC18168915 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238769 CCOC(=O)C(=NNc1ncnc2ccccc12)c1ccc(C)cc1 InChI=1S/C19H18N4O2/c1-3-25-19(24)17(14-10-8-13(2)9-11-14)22-23-18-15-6-4-5-7-16(15)20-12-21-18/h4-12H,3H2,1-2H3,(H,20,21,23) NODKTAFDLVLLRV-UHFFFAOYSA-N 76704 (2Z)-2-(p-tolyl)-2-(quinazolin-4-ylhydrazono)acetic acid ethyl ester::2-(4-methylphenyl)-2-(4-quinazolinylhydrazinylidene)acetic acid ethyl ester::2-(p-tolyl)-2-(quinazolin-4-ylhydrazono)acetic acid ethyl ester::MLS001176690::SMR000595544::cid_24761663::ethyl 2-(4-methylphenyl)-2-(quinazolin-4-ylhydrazinylidene)acetate::ethyl 2-(4-methylphenyl)-2-(quinazolin-4-ylhydrazinylidene)ethanoate Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76704&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9717959 252653881 ZINC12473392 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238770 Nc1cccc2C(=O)N(CCOc3ccccc3F)C(=O)c12 InChI=1S/C16H13FN2O3/c17-11-5-1-2-7-13(11)22-9-8-19-15(20)10-4-3-6-12(18)14(10)16(19)21/h1-7H,8-9,18H2 ILAVPZWPAIWSBL-UHFFFAOYSA-N 114805 4-amino-2-[2-(2-fluorophenoxy)ethyl]isoindole-1,3-dione::4-amino-2-[2-(2-fluorophenoxy)ethyl]isoindoline-1,3-quinone::4-azanyl-2-[2-(2-fluoranylphenoxy)ethyl]isoindole-1,3-dione::MLS001174542::SMR000589780::cid_2092383 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114805&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2092383 252664277 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238771 Oc1ccccc1C(=O)Nc1ccc2ccccc2c1 InChI=1S/C17H13NO2/c19-16-8-4-3-7-15(16)17(20)18-14-10-9-12-5-1-2-6-13(12)11-14/h1-11,19H,(H,18,20) KFLNUTIUYWTQNV-UHFFFAOYSA-N 95946 2-hydroxy-N-(2-naphthalenyl)benzamide::2-hydroxy-N-(2-naphthyl)benzamide::2-hydroxy-N-naphthalen-2-ylbenzamide::MLS001166722::N-naphthalen-2-yl-2-oxidanyl-benzamide::SMR000595197::cid_219325 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95946&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 219325 164037190 ZINC01555555 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238772 Brc1ccccc1C1NC(=NO1)c1ccccc1 InChI=1S/C14H11BrN2O/c15-12-9-5-4-8-11(12)14-16-13(17-18-14)10-6-2-1-3-7-10/h1-9,14H,(H,16,17) WRHPNBSQUJFECI-UHFFFAOYSA-N 114806 5-(2-bromophenyl)-3-phenyl-2,5-dihydro-1,2,4-oxadiazole::MLS001176841::SMR000596494::cid_4463708 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114806&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4463708 252664278 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238773 Cc1[nH]n(C(N)=S)c(=O)c1N=Nc1ccc(Br)cc1 InChI=1S/C11H10BrN5OS/c1-6-9(10(18)17(16-6)11(13)19)15-14-8-4-2-7(12)3-5-8/h2-5,16H,1H3,(H2,13,19) KMUKJMGGGCHKSR-UHFFFAOYSA-N 114794 (4E)-4-[(4-bromophenyl)hydrazono]-5-keto-3-methyl-2-pyrazoline-1-carbothioamide::4-(4-Bromo-phenylazo)-3-methyl-5-oxo-4,5-dihydro-pyrazole-1-carbothioic acid amide::4-(4-bromophenyl)azo-3-methyl-5-oxo-4H-pyrazole-1-carbothioamide::4-(4-bromophenyl)azo-5-keto-3-methyl-2-pyrazoline-1-carbothioamide::4-[(4-bromophenyl)diazenyl]-3-methyl-5-oxidanylidene-4H-pyrazole-1-carbothioamide::4-[(4-bromophenyl)diazenyl]-3-methyl-5-oxo-4H-pyrazole-1-carbothioamide::MLS001210117::SMR000514003::cid_3106491 Oxysterols receptor LXR-beta 67496 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114794&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5800217 252664267 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238774 Nc1nc2c(nnn2c2ccccc12)-c1ccc(Br)cc1 InChI=1S/C15H10BrN5/c16-10-7-5-9(6-8-10)13-15-18-14(17)11-3-1-2-4-12(11)21(15)20-19-13/h1-8H,(H2,17,18) VJSJQHOXJLXWRP-UHFFFAOYSA-N 114808 3-(4-bromophenyl)-5-triazolo[1,5-a]quinazolinamine::3-(4-bromophenyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine::3-(4-bromophenyl)triazolo[1,5-a]quinazolin-5-amine::MLS001181630::SMR000567315::[3-(4-bromophenyl)triazolo[1,5-a]quinazolin-5-yl]amine::cid_2804214 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114808&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2804214 252664279 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238775 Fc1ccccc1NC(=O)Nc1nc2ccccc2[nH]1 InChI=1S/C14H11FN4O/c15-9-5-1-2-6-10(9)18-14(20)19-13-16-11-7-3-4-8-12(11)17-13/h1-8H,(H3,16,17,18,19,20) XEEVCOVNDDLYGV-UHFFFAOYSA-N 76719 1-(1H-benzimidazol-2-yl)-3-(2-fluorophenyl)urea::MLS001172858::SMR000589803::cid_4963407 Oxysterols receptor LXR-beta 67520 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76719&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4963407 252653896 ZINC05267382 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238776 Clc1ccccc1-c1cc(no1)C(=O)N1CCCC1 InChI=1S/C14H13ClN2O2/c15-11-6-2-1-5-10(11)13-9-12(16-19-13)14(18)17-7-3-4-8-17/h1-2,5-6,9H,3-4,7-8H2 CAVPPTIDSYUOLB-UHFFFAOYSA-N 114809 MLS001216883::SMR000612814::[5-(2-Chloro-phenyl)-isoxazol-3-yl]-pyrrolidin-1-yl-methanone::[5-(2-chlorophenyl)-1,2-oxazol-3-yl]-pyrrolidin-1-yl-methanone::[5-(2-chlorophenyl)-1,2-oxazol-3-yl]-pyrrolidin-1-ylmethanone::[5-(2-chlorophenyl)-3-isoxazolyl]-(1-pyrrolidinyl)methanone::[5-(2-chlorophenyl)isoxazol-3-yl]-pyrrolidino-methanone::cid_1093868 Oxysterols receptor LXR-beta 67500 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114809&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1093868 252664280 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238777 CC1CCCCN1C(=O)CSc1nnc(o1)-c1ccccc1O InChI=1S/C16H19N3O3S/c1-11-6-4-5-9-19(11)14(21)10-23-16-18-17-15(22-16)12-7-2-3-8-13(12)20/h2-3,7-8,11,20H,4-6,9-10H2,1H3 RTLQWJIUROGJRD-UHFFFAOYSA-N 114810 (6Z)-6-[5-[2-(2-methylpiperidin-1-yl)-2-oxidanylidene-ethyl]sulfanyl-3H-1,3,4-oxadiazol-2-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[5-[2-(2-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3H-1,3,4-oxadiazol-2-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[5-[[2-(2-methyl-1-piperidinyl)-2-oxoethyl]thio]-3H-1,3,4-oxadiazol-2-ylidene]-1-cyclohexa-2,4-dienone::(6Z)-6-[5-[[2-keto-2-(2-methylpiperidino)ethyl]thio]-3H-1,3,4-oxadiazol-2-ylidene]cyclohexa-2,4-dien-1-one::2-[5-(2-Hydroxy-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-1-(2-methyl-piperidin-1-yl)-ethanone::MLS001221414::SMR000599968::cid_5938646 Oxysterols receptor LXR-beta 67485 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114810&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5938646 252664281 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238778 COc1ccccc1C(=O)NC(=S)Nc1cccnc1Cl InChI=1S/C14H12ClN3O2S/c1-20-11-7-3-2-5-9(11)13(19)18-14(21)17-10-6-4-8-16-12(10)15/h2-8H,1H3,(H2,17,18,19,21) ZCKLACTUTMWGMO-UHFFFAOYSA-N 114811 MLS000936812::N-[(2-chloranylpyridin-3-yl)carbamothioyl]-2-methoxy-benzamide::N-[(2-chloro-3-pyridyl)thiocarbamoyl]-2-methoxy-benzamide::N-[(2-chloropyridin-3-yl)carbamothioyl]-2-methoxybenzamide::N-[[(2-chloro-3-pyridinyl)amino]-sulfanylidenemethyl]-2-methoxybenzamide::SMR000621429::cid_768734 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114811&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 768734 252664282 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238779 CCc1ccc(NC(=O)Nc2ccsc2C(=O)OC)cc1 InChI=1S/C15H16N2O3S/c1-3-10-4-6-11(7-5-10)16-15(19)17-12-8-9-21-13(12)14(18)20-2/h4-9H,3H2,1-2H3,(H2,16,17,19) PISFGKBDZWQQFD-UHFFFAOYSA-N 114812 3-[(4-ethylphenyl)carbamoylamino]thiophene-2-carboxylic acid methyl ester::3-[[(4-ethylanilino)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester::MLS001229826::SMR000678187::cid_24818579::methyl 3-[(4-ethylphenyl)carbamoylamino]thiophene-2-carboxylate Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114812&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24818579 252664283 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238780 Cc1ccnc(NC(=O)Cc2ccc(cc2)-c2ccccc2)c1 InChI=1S/C20H18N2O/c1-15-11-12-21-19(13-15)22-20(23)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-13H,14H2,1H3,(H,21,22,23) RHYNLNMKHHGIKE-UHFFFAOYSA-N 97279 MLS001149295::N-(4-methyl-2-pyridinyl)-2-(4-phenylphenyl)acetamide::N-(4-methyl-2-pyridyl)-2-(4-phenylphenyl)acetamide::N-(4-methylpyridin-2-yl)-2-(4-phenylphenyl)acetamide::N-(4-methylpyridin-2-yl)-2-(4-phenylphenyl)ethanamide::SMR000688399::cid_24238955 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97279&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24238955 164038523 ZINC12641823 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238781 COc1ccc2oc(C(=O)Nc3ccccn3)c(C)c2c1 InChI=1S/C16H14N2O3/c1-10-12-9-11(20-2)6-7-13(12)21-15(10)16(19)18-14-5-3-4-8-17-14/h3-9H,1-2H3,(H,17,18,19) YZLNIEFMQRLAHX-UHFFFAOYSA-N 114813 5-methoxy-3-methyl-N-(2-pyridinyl)-2-benzofurancarboxamide::5-methoxy-3-methyl-N-(2-pyridyl)coumarilamide::5-methoxy-3-methyl-N-pyridin-2-yl-1-benzofuran-2-carboxamide::MLS001079001::SMR000713001::cid_16382764 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114813&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16382764 252664284 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238782 COc1c(Cl)scc1C(=O)Nc1nnc(s1)C1CC1 InChI=1S/C11H10ClN3O2S2/c1-17-7-6(4-18-8(7)12)9(16)13-11-15-14-10(19-11)5-2-3-5/h4-5H,2-3H2,1H3,(H,13,15,16) PNDTYUXKRXUUIH-UHFFFAOYSA-N 114814 5-chloranyl-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-4-methoxy-thiophene-3-carboxamide::5-chloro-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-4-methoxy-3-thiophenecarboxamide::5-chloro-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-4-methoxy-thiophene-3-carboxamide::5-chloro-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-4-methoxythiophene-3-carboxamide::MLS001098042::SMR000657664::cid_2814043 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114814&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2814043 252664285 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238783 Cc1ccc(cc1)-c1cc(no1)-c1ccccc1 InChI=1S/C16H13NO/c1-12-7-9-14(10-8-12)16-11-15(17-18-16)13-5-3-2-4-6-13/h2-11H,1H3 DTBZUMKAINUIIW-UHFFFAOYSA-N 76753 3-phenyl-5-(p-tolyl)isoxazole::5-(4-methylphenyl)-3-phenyl-1,2-oxazole::5-(4-methylphenyl)-3-phenylisoxazole::MLS001242722::SMR000841528::cid_296680 Oxysterols receptor LXR-beta 67504 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 296680 252653930 ZINC01660041 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238784 Cc1csc(NC(=O)c2oc3ccccc3c2C)n1 InChI=1S/C14H12N2O2S/c1-8-7-19-14(15-8)16-13(17)12-9(2)10-5-3-4-6-11(10)18-12/h3-7H,1-2H3,(H,15,16,17) XWTCXKKCZQASHJ-UHFFFAOYSA-N 114815 3-methyl-N-(4-methyl-1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide::3-methyl-N-(4-methyl-2-thiazolyl)-2-benzofurancarboxamide::3-methyl-N-(4-methylthiazol-2-yl)coumarilamide::MLS001139556::SMR000715021::cid_7770823 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114815&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7770823 252664286 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238785 OC[C@H]1O[C@H](C[C@@H]1O)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1 WOVKYSAHUYNSMH-RRKCRQDMSA-N 50207303 5-BROMO-2'-DEOXY URIDINE::5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione::Bromodeoxyuridine::CHEMBL222280::cid_6035 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50207303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50207303&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search U33 2GRB 6035 104084911 472552 CHEMBL222280 ZINC01081243 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238786 COc1ccc(cc1)-c1cc2ccccc2cn1 InChI=1S/C16H13NO/c1-18-15-8-6-12(7-9-15)16-10-13-4-2-3-5-14(13)11-17-16/h2-11H,1H3 VBCFPFDUNNOWIZ-UHFFFAOYSA-N 96071 3-(4-methoxyphenyl)isoquinoline::MLS002391737::SMR001355702::cid_2752930 Oxysterols receptor LXR-beta 67528 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2752930 164037315 ZINC03848043 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238787 CN(C)c1ccc(cc1)-c1cc2ccccc2c(=O)o1 InChI=1S/C17H15NO2/c1-18(2)14-9-7-12(8-10-14)16-11-13-5-3-4-6-15(13)17(19)20-16/h3-11H,1-2H3 KMRJHLYHSGQPDJ-UHFFFAOYSA-N 114816 3-[4-(dimethylamino)phenyl]-2-benzopyran-1-one::3-[4-(dimethylamino)phenyl]isochromen-1-one::3-[4-(dimethylamino)phenyl]isocoumarin::MLS001308081::SMR001216465::cid_25058362 Oxysterols receptor LXR-beta 67642 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114816&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25058362 252664287 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238788 O=C(CSc1nncs1)Nc1sccc1C#N InChI=1S/C9H6N4OS3/c10-3-6-1-2-15-8(6)12-7(14)4-16-9-13-11-5-17-9/h1-2,5H,4H2,(H,12,14) BVDIVRHFGIGDCM-UHFFFAOYSA-N 114817 MLS002251598::N-(3-cyano-2-thienyl)-2-(1,3,4-thiadiazol-2-ylthio)acetamide::N-(3-cyano-2-thiophenyl)-2-(1,3,4-thiadiazol-2-ylthio)acetamide::N-(3-cyanothiophen-2-yl)-2-(1,3,4-thiadiazol-2-ylsulfanyl)acetamide::N-(3-cyanothiophen-2-yl)-2-(1,3,4-thiadiazol-2-ylsulfanyl)ethanamide::SMR001313987::cid_2532005 Oxysterols receptor LXR-beta 67507 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114817&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2532005 252664288 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238789 C[C@]12[C@H]([C@H]3COc4ccccc4[C@@H]3N1C(=O)c1cc(Cl)ccc1NC2=O)c1ccccc1 InChI=1S/C26H21ClN2O3/c1-26-22(15-7-3-2-4-8-15)19-14-32-21-10-6-5-9-17(21)23(19)29(26)24(30)18-13-16(27)11-12-20(18)28-25(26)31/h2-13,19,22-23H,14H2,1H3,(H,28,31)/t19-,22+,23+,26-/m1/s1 GHYZYEWFTIVWLF-WVIBYCHQSA-N 77929 MLS002174170::SMR001261337::cid_25102468 Oxysterols receptor LXR-beta 67399 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77929&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102468 242053623 ZINC05687435 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238790 COc1ccc(cc1)-n1nc2cc(C)c(N)c(Br)c2n1 InChI=1S/C14H13BrN4O/c1-8-7-11-14(12(15)13(8)16)18-19(17-11)9-3-5-10(20-2)6-4-9/h3-7H,16H2,1-2H3 KDTXZMQLDJGXRG-UHFFFAOYSA-N 34628 4-bromanyl-2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-amine::4-bromo-2-(4-methoxyphenyl)-6-methyl-2H-1,2,3-benzotriazol-5-amine::4-bromo-2-(4-methoxyphenyl)-6-methyl-5-benzotriazolamine::4-bromo-2-(4-methoxyphenyl)-6-methylbenzotriazol-5-amine::MLS000052623::SMR000082196::[4-bromo-2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-yl]amine::cid_2236497 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34628&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2236497 252617279 ZINC02884195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238791 CC(C)c1ccc(CN=Nc2ccc(cn2)[N+]([O-])=O)cc1 InChI=1S/C15H16N4O2/c1-11(2)13-5-3-12(4-6-13)9-17-18-15-8-7-14(10-16-15)19(20)21/h3-8,10-11H,9H2,1-2H3 NNRZTCCPCBFBMH-UHFFFAOYSA-N 114818 5-nitro-N-[(4-propan-2-ylphenyl)methylideneamino]-2-pyridinamine::5-nitro-N-[(4-propan-2-ylphenyl)methylideneamino]pyridin-2-amine::MLS002608483::SMR001527231::[(4-isopropylbenzylidene)amino]-(5-nitro-2-pyridyl)amine::cid_95915 Oxysterols receptor LXR-beta 67629 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114818&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 54121017 252664289 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238792 O=C1C(Cc2ccccc12)=C1CCc2ccccc12 InChI=1S/C18H14O/c19-18-15-8-4-2-6-13(15)11-17(18)16-10-9-12-5-1-3-7-14(12)16/h1-8H,9-11H2 GDGCNJMFHOCJEH-UHFFFAOYSA-N 114819 2-(1-Indanylidene)-1-indanone::2-(2,3-dihydroinden-1-ylidene)-3H-inden-1-one::2-indan-1-ylideneindan-1-one::MLS002638557::SMR001548030::cid_226774 Oxysterols receptor LXR-beta 67439 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114819&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 226774 252664290 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238793 Clc1ccc(C=Cc2ccccn2)c(Cl)c1 InChI=1S/C13H9Cl2N/c14-11-6-4-10(13(15)9-11)5-7-12-3-1-2-8-16-12/h1-9H RKOSAWWBEHBDKH-UHFFFAOYSA-N 93915 2-[2-(2,4-dichlorophenyl)ethenyl]pyridine::2-[2-(2,4-dichlorophenyl)vinyl]pyridine::MLS002637619::SMR001547146::cid_220147 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93915&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 220147 164035159 ZINC04817536 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238794 NC(=O)c1c(NC(=O)c2cc3ccccc3o2)sc2CCCc12 InChI=1S/C17H14N2O3S/c18-15(20)14-10-5-3-7-13(10)23-17(14)19-16(21)12-8-9-4-1-2-6-11(9)22-12/h1-2,4,6,8H,3,5,7H2,(H2,18,20)(H,19,21) BEDOWVBPFLCOBB-UHFFFAOYSA-N 39980 MLS000099000::N-(3-aminocarbonyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-1-benzofuran-2-carboxamide::N-(3-carbamoyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-1-benzofuran-2-carboxamide::N-(3-carbamoyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-2-benzofurancarboxamide::N-(3-carbamoyl-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)coumarilamide::SMR000062987::cid_2439735 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39980&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2439735 252620811 ZINC03324261 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238795 CNc1ccc(C=C2C=Cc3ccccc23)cc1 InChI=1S/C17H15N/c1-18-16-10-6-13(7-11-16)12-15-9-8-14-4-2-3-5-17(14)15/h2-12,18H,1H3 NGLDRQSSOKKORP-UHFFFAOYSA-N 93918 4-(1-indenylidenemethyl)-N-methylaniline::4-(inden-1-ylidenemethyl)-N-methyl-aniline::4-(inden-1-ylidenemethyl)-N-methylaniline::Benzenamine, 4-(1H-inden-1-ylidenemethyl)-N-methyl-::MLS002694461::SMR001560390::[4-(inden-1-ylidenemethyl)phenyl]-methyl-amine::cid_98136 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93918&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 98136 164035162 ZINC17354169 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238796 Cc1cc2NP(=S)(Nc2cc1C)c1ccccc1 InChI=1S/C14H15N2PS/c1-10-8-13-14(9-11(10)2)16-17(18,15-13)12-6-4-3-5-7-12/h3-9H,1-2H3,(H2,15,16,18) QSDRGJPZPNMKCD-UHFFFAOYSA-N 114820 5,6-dimethyl-2-phenyl-2-sulfanylidene-1,3-dihydro-1,3,2-benzodiazaphosphole::5,6-dimethyl-2-phenyl-2-thioxo-1,3-dihydro-1,3,2-benzodiazaphosphole::MLS002694835::SMR001560753::cid_258924 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114820&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 258924 252664291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238797 Fc1ccc(cc1)-c1nnc(o1)-c1ccc2ccccc2c1 InChI=1S/C18H11FN2O/c19-16-9-7-13(8-10-16)17-20-21-18(22-17)15-6-5-12-3-1-2-4-14(12)11-15/h1-11H BFFQFOBHPRLZCN-UHFFFAOYSA-N 114821 2-(4-fluorophenyl)-5-(2-naphthalenyl)-1,3,4-oxadiazole::2-(4-fluorophenyl)-5-(2-naphthyl)-1,3,4-oxadiazole::2-(4-fluorophenyl)-5-naphthalen-2-yl-1,3,4-oxadiazole::MLS002694978::SMR001560891::cid_96845 Oxysterols receptor LXR-beta 67508 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114821&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 96845 252664292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238798 Cc1ccc(cc1)-c1nnc(o1)-c1cccc2ccccc12 InChI=1S/C19H14N2O/c1-13-9-11-15(12-10-13)18-20-21-19(22-18)17-8-4-6-14-5-2-3-7-16(14)17/h2-12H,1H3 ISTKKLXTQRJPRV-UHFFFAOYSA-N 95887 2-(1-naphthyl)-5-(p-tolyl)-1,3,4-oxadiazole::2-(4-methylphenyl)-5-(1-naphthalenyl)-1,3,4-oxadiazole::2-(4-methylphenyl)-5-naphthalen-1-yl-1,3,4-oxadiazole::MLS002695030::SMR001560943::cid_260001 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95887&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 260001 164037131 ZINC01581023 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238799 C(=Cc1nccc2ccccc12)c1c[nH]c2ccccc12 InChI=1S/C19H14N2/c1-2-6-16-14(5-1)11-12-20-19(16)10-9-15-13-21-18-8-4-3-7-17(15)18/h1-13,21H GXWLLYOLXFYXAT-UHFFFAOYSA-N 114822 1-[2-(1H-indol-3-yl)ethenyl]isoquinoline::1-[2-(1H-indol-3-yl)vinyl]isoquinoline::MLS002694045::SMR001559978::cid_254080 Oxysterols receptor LXR-beta 67442 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114822&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 254080 252664293 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238800 Cc1cc(ccc1N)-c1nc2ccccc2s1 InChI=1S/C14H12N2S/c1-9-8-10(6-7-11(9)15)14-16-12-4-2-3-5-13(12)17-14/h2-8H,15H2,1H3 IDBCUMFOZBUJCL-UHFFFAOYSA-N 50141278 2-(4-Amino-3-methylphenyl)benzothiazole::4-(3H-1lambda*4*-Benzothiazol-2-yl)-2-methyl-phenylamine::4-(benzo[d]thiazol-2-yl)-2-methylbenzenamine::4-Benzothiazol-2-yl-2-methyl-phenyl amine::4-Benzothiazol-2-yl-2-methyl-phenylamine::CHEMBL11825::cid_384525 Oxysterols receptor LXR-beta 67649 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141278&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search BM8 6EOY 384525 104030737 CHEMBL11825 ZINC00006701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238801 Oc1cccc(c1)-c1nnc(nn1)-c1cccc(O)c1 InChI=1S/C14H10N4O2/c19-11-5-1-3-9(7-11)13-15-17-14(18-16-13)10-4-2-6-12(20)8-10/h1-8,19-20H YDADTNARCJIMQM-UHFFFAOYSA-N 25867 3-[6-(3-hydroxyphenyl)-1,2,4,5-tetrazin-3-yl]phenol::cid_269792::hydroxyphenyl substituted tetrazine, 39 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25867&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 269792 56413155 ZINC01703222 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238802 C1C2COc3ccccc3C2=NN1c1ccccc1 InChI=1S/C16H14N2O/c1-2-6-13(7-3-1)18-10-12-11-19-15-9-5-4-8-14(15)16(12)17-18/h1-9,12H,10-11H2 DATNOZAQAIEORG-UHFFFAOYSA-N 114823 2-phenyl-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]pyrazole::2-phenyl-3a,4-dihydro-3H-chromeno[4,3-c]pyrazole::MLS002706663::SMR001574064::cid_272282 Oxysterols receptor LXR-beta 67432 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114823&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 272282 252664294 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238803 Clc1ccccc1N=NCc1ccccn1 InChI=1S/C12H10ClN3/c13-11-6-1-2-7-12(11)16-15-9-10-5-3-4-8-14-10/h1-8H,9H2 UCUVHLJWNGWLJK-UHFFFAOYSA-N 114824 (2-chlorophenyl)-(2-pyridylmethyleneamino)amine::2-chloranyl-N-(pyridin-2-ylmethylideneamino)aniline::2-chloro-N-(2-pyridinylmethylideneamino)aniline::2-chloro-N-(pyridin-2-ylmethylideneamino)aniline::MLS002920042::SMR001797641::cid_279303 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114824&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899737 252664295 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238804 Nc1ccccc1-n1nc2ccc3ccccc3c2n1 InChI=1S/C16H12N4/c17-13-7-3-4-8-15(13)20-18-14-10-9-11-5-1-2-6-12(11)16(14)19-20/h1-10H,17H2 WMCKDNPVZDYHGP-UHFFFAOYSA-N 114825 (2-benzo[e]benzotriazol-2-ylphenyl)amine::2-(2-benzo[e]benzotriazolyl)aniline::2-benzo[e]benzotriazol-2-ylaniline::MLS003106484::SMR001821386::cid_292642 Oxysterols receptor LXR-beta 67523 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114825&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 292642 252664296 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238805 COc1cccc(c1)-c1nc2-c3ccccc3CCn2n1 InChI=1S/C17H15N3O/c1-21-14-7-4-6-13(11-14)16-18-17-15-8-3-2-5-12(15)9-10-20(17)19-16/h2-8,11H,9-10H2,1H3 OITUZFHSDXLWBR-UHFFFAOYSA-N 114826 2-(3-methoxyphenyl)-5,6-dihydro-[1,2,4]triazol[5,1-a]isoquinoline::2-(3-methoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-a]isoquinoline::L 10503::MLS003115726::SMR001831297::cid_100434 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114826&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 100434 252664297 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238806 C1Oc2cc3nn-4c(OCc5ccccc-45)c3cc2O1 InChI=1S/C15H10N2O3/c1-2-4-12-9(3-1)7-18-15-10-5-13-14(20-8-19-13)6-11(10)16-17(12)15/h1-6H,7-8H2 AYQUHPYWEYGYCI-UHFFFAOYSA-N 95912 MLS003151681::SMR001856274::cid_46904963 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95912&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46904963 164037156 ZINC61920911 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238807 CCCc1nc2c(C)cc(Br)cn2c1Cc1ccc(C)cc1 InChI=1S/C19H21BrN2/c1-4-5-17-18(11-15-8-6-13(2)7-9-15)22-12-16(20)10-14(3)19(22)21-17/h6-10,12H,4-5,11H2,1-3H3 PYJOVWSQUCOBMY-UHFFFAOYSA-N 114827 6-bromanyl-8-methyl-3-[(4-methylphenyl)methyl]-2-propyl-imidazo[1,2-a]pyridine::6-bromo-8-methyl-3-(4-methylbenzyl)-2-propyl-imidazo[1,2-a]pyridine::6-bromo-8-methyl-3-[(4-methylphenyl)methyl]-2-propylimidazo[1,2-a]pyridine::MLS003222318::SMR001906873::cid_51359041 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114827&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 51359041 252664298 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238808 C1Oc2ccc(Nc3nc(cs3)-c3ccccc3)cc2O1 InChI=1S/C16H12N2O2S/c1-2-4-11(5-3-1)13-9-21-16(18-13)17-12-6-7-14-15(8-12)20-10-19-14/h1-9H,10H2,(H,17,18) VCCSHBSYIOMBBU-UHFFFAOYSA-N 50382181 CHEMBL1894768::cid_684847 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382181&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 684847 160861264 CHEMBL1894768 ZINC00051594 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238809 NC(=NC(=S)Nc1ccc2OCOc2c1)c1ccccc1 InChI=1S/C15H13N3O2S/c16-14(10-4-2-1-3-5-10)18-15(21)17-11-6-7-12-13(8-11)20-9-19-12/h1-8H,9H2,(H3,16,17,18,21) CBUOHALHKBRDTB-UHFFFAOYSA-N 114828 (1Z)-1-[amino(phenyl)methylene]-3-(1,3-benzodioxol-5-yl)thiourea::(1Z)-1-[amino(phenyl)methylidene]-3-(1,3-benzodioxol-5-yl)thiourea::(1Z)-1-[azanyl(phenyl)methylidene]-3-(1,3-benzodioxol-5-yl)thiourea::MLS003315839::SMR001994974::cid_51360485 Oxysterols receptor LXR-beta 67507 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114828&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 51360485 252664299 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238810 CC(C)(C)c1ccc(Nc2n[nH]c3ccccc23)cc1 InChI=1S/C17H19N3/c1-17(2,3)12-8-10-13(11-9-12)18-16-14-6-4-5-7-15(14)19-20-16/h4-11H,1-3H3,(H2,18,19,20) RACMIUAAKPPEPS-UHFFFAOYSA-N 114829 (4-tert-butylphenyl)-(1H-indazol-3-yl)amine::MLS003269464::N-(4-tert-butylphenyl)-1H-indazol-3-amine::SMR001949433::cid_51361059 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114829&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 51361059 252664300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238811 COc1ccc(cc1)-c1cc2ccccc2c(=O)o1 InChI=1S/C16H12O3/c1-18-13-8-6-11(7-9-13)15-10-12-4-2-3-5-14(12)16(17)19-15/h2-10H,1H3 LCTOHXUIVJEHSV-UHFFFAOYSA-N 114830 3-(4-methoxyphenyl)-1H-isochromen-1-one::3-(4-methoxyphenyl)-2-benzopyran-1-one::3-(4-methoxyphenyl)isochromen-1-one::3-(4-methoxyphenyl)isocoumarin::MLS001360841::SMR000743609::cid_275900 Oxysterols receptor LXR-beta 67468 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114830&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 275900 252664301 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238813 CC(C)(C)NC(=O)C(c1cc2ccccc2o1)n1c(nc2ccccc12)-c1ccc(cc1)-c1ccccc1 InChI=1S/C33H29N3O2/c1-33(2,3)35-32(37)30(29-21-25-13-7-10-16-28(25)38-29)36-27-15-9-8-14-26(27)34-31(36)24-19-17-23(18-20-24)22-11-5-4-6-12-22/h4-21,30H,1-3H3,(H,35,37) TZZMXEBNOJXGSI-UHFFFAOYSA-N 114832 2-(1-benzofuran-2-yl)-N-tert-butyl-2-[2-(4-phenylphenyl)benzimidazol-1-yl]acetamide::2-(1-benzofuran-2-yl)-N-tert-butyl-2-[2-(4-phenylphenyl)benzimidazol-1-yl]ethanamide::2-(2-benzofuranyl)-N-tert-butyl-2-[2-(4-phenylphenyl)-1-benzimidazolyl]acetamide::2-(benzofuran-2-yl)-N-tert-butyl-2-[2-(4-phenylphenyl)benzimidazol-1-yl]acetamide::MLS003674655::SMR002353949::cid_53383229 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114832&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53383229 252664303 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238814 Cc1ccc2nc(oc2c1)-c1ccccn1 InChI=1S/C13H10N2O/c1-9-5-6-10-12(8-9)16-13(15-10)11-4-2-3-7-14-11/h2-8H,1H3 FCVLTYALDWKRND-UHFFFAOYSA-N 114962 6-Methyl-2-pyridin-2-yl-benzooxazole::6-methyl-2-(2-pyridinyl)-1,3-benzoxazole::6-methyl-2-(2-pyridyl)-1,3-benzoxazole::6-methyl-2-pyridin-2-yl-1,3-benzoxazole::MLS000033711::SMR000013748::cid_646454 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114962&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 646454 252664424 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238815 Cn1c(SCc2ccccc2F)nc2cccnc12 InChI=1S/C14H12FN3S/c1-18-13-12(7-4-8-16-13)17-14(18)19-9-10-5-2-3-6-11(10)15/h2-8H,9H2,1H3 FFHQCGKIMJHDFG-UHFFFAOYSA-N 39520 2-(2-Fluoro-benzylsulfanyl)-3-methyl-3H-imidazo[4,5-b]pyridine::2-[(2-fluorobenzyl)thio]-3-methyl-imidazo[4,5-b]pyridine::2-[(2-fluorophenyl)methylsulfanyl]-3-methyl-imidazo[4,5-b]pyridine::2-[(2-fluorophenyl)methylsulfanyl]-3-methylimidazo[4,5-b]pyridine::2-[(2-fluorophenyl)methylthio]-3-methylimidazo[4,5-b]pyridine::MLS000073602::SMR000006767::cid_649231 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39520&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 649231 252620412 ZINC01346450 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238816 C1CN(CCO1)c1ccc(cc1)-c1nnc(o1)-c1cccs1 InChI=1S/C16H15N3O2S/c1-2-14(22-11-1)16-18-17-15(21-16)12-3-5-13(6-4-12)19-7-9-20-10-8-19/h1-6,11H,7-10H2 NBZCJRUGPOBOJX-UHFFFAOYSA-N 95939 4-[4-(5-Thiophen-2-yl-[1,3,4]oxadiazol-2-yl)-phenyl]-morpholine::4-[4-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)phenyl]morpholine::4-[4-[5-(2-thienyl)-1,3,4-oxadiazol-2-yl]phenyl]morpholine::MLS000026817::SMR000002070::cid_650568 Oxysterols receptor LXR-beta 67522 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 650568 164037183 ZINC00420057 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238817 Cn1c(NCc2c[nH]c3ccccc23)nc2ccccc12 InChI=1S/C17H16N4/c1-21-16-9-5-4-8-15(16)20-17(21)19-11-12-10-18-14-7-3-2-6-13(12)14/h2-10,18H,11H2,1H3,(H,19,20) FOIVXEQNSMOVOD-UHFFFAOYSA-N 114963 (1H-Indol-3-ylmethyl)-(1-methyl-1H-benzoimidazol-2-yl)-amine::1H-indol-3-ylmethyl-(1-methylbenzimidazol-2-yl)amine::MLS000034035::N-(1H-indol-3-ylmethyl)-1-methyl-2-benzimidazolamine::N-(1H-indol-3-ylmethyl)-1-methyl-benzimidazol-2-amine::N-(1H-indol-3-ylmethyl)-1-methylbenzimidazol-2-amine::SMR000013297::cid_652872 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114963&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652872 252664425 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238818 CCOC(=O)CSc1nc(ccc1C#N)-c1ccncc1 InChI=1S/C15H13N3O2S/c1-2-20-14(19)10-21-15-12(9-16)3-4-13(18-15)11-5-7-17-8-6-11/h3-8H,2,10H2,1H3 PSOFEUJECPFMAT-UHFFFAOYSA-N 39435 2-[(3-cyano-6-pyridin-4-yl-2-pyridinyl)thio]acetic acid ethyl ester::2-[[3-cyano-6-(4-pyridyl)-2-pyridyl]thio]acetic acid ethyl ester::MLS000027979::SMR000038899::cid_657961::ethyl 2-(3-cyano-6-pyridin-4-yl-pyridin-2-yl)sulfanylethanoate::ethyl 2-(3-cyano-6-pyridin-4-ylpyridin-2-yl)sulfanylacetate Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39435&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 657961 252620327 ZINC00495572 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238819 CN1CCN(CC1)\C=N\c1sc2CCCCCc2c1C#N InChI=1S/C16H22N4S/c1-19-7-9-20(10-8-19)12-18-16-14(11-17)13-5-3-2-4-6-15(13)21-16/h12H,2-10H2,1H3/b18-12+ FCMGAQVDVZZVMS-LDADJPATSA-N 114964 2-[(E)-(4-methyl-1-piperazinyl)methylideneamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile::2-[(E)-(4-methylpiperazin-1-yl)methylideneamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile::2-[(E)-(4-methylpiperazino)methyleneamino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile::MLS000027580::SMR000037262::cid_9568654 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114964&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9568654 252664426 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238821 COc1cccc(c1)-c1noc(n1)-c1cccs1 InChI=1S/C13H10N2O2S/c1-16-10-5-2-4-9(8-10)12-14-13(17-15-12)11-6-3-7-18-11/h2-8H,1H3 NWPANAJPHRXMQR-UHFFFAOYSA-N 39543 3-(3-methoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole::3-(3-methoxyphenyl)-5-thiophen-2-yl-1,2,4-oxadiazole::MLS000083721::SMR000047269::cid_665971 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39543&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 665971 252620434 ZINC02440132 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238822 Cc1nn(c(N)c1Sc1ccc(F)cc1)-c1nc(C)cc(C)n1 InChI=1S/C16H16FN5S/c1-9-8-10(2)20-16(19-9)22-15(18)14(11(3)21-22)23-13-6-4-12(17)5-7-13/h4-8H,18H2,1-3H3 UHKSHIBWGZYKCL-UHFFFAOYSA-N 37328 2-(4,6-dimethyl-2-pyrimidinyl)-4-[(4-fluorophenyl)thio]-5-methyl-3-pyrazolamine::2-(4,6-dimethylpyrimidin-2-yl)-4-(4-fluorophenyl)sulfanyl-5-methyl-pyrazol-3-amine::2-(4,6-dimethylpyrimidin-2-yl)-4-(4-fluorophenyl)sulfanyl-5-methylpyrazol-3-amine::MLS000081884::SMR000060530::[2-(4,6-dimethylpyrimidin-2-yl)-4-[(4-fluorophenyl)thio]-5-methyl-pyrazol-3-yl]amine::cid_2321431 Oxysterols receptor LXR-beta 67520 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37328&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2321431 252618299 ZINC03192470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238823 Oc1ccccc1-c1cc([nH]n1)-c1ccc2OCCOc2c1 InChI=1S/C17H14N2O3/c20-15-4-2-1-3-12(15)14-10-13(18-19-14)11-5-6-16-17(9-11)22-8-7-21-16/h1-6,9-10,20H,7-8H2,(H,18,19) BHAIJGZQJXALAJ-UHFFFAOYSA-N 49227 (6E)-6-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::MLS000097909::SMR000060538::cid_5742561 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49227&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5742561 252629508 ZINC13124383 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238824 O=C(NCCCn1ccnc1)c1cc(on1)-c1cccs1 InChI=1S/C14H14N4O2S/c19-14(16-4-2-6-18-7-5-15-10-18)11-9-12(20-17-11)13-3-1-8-21-13/h1,3,5,7-10H,2,4,6H2,(H,16,19) LRGVDHZAEYAHLG-UHFFFAOYSA-N 49229 MLS000087245::N-(3-imidazol-1-ylpropyl)-5-(2-thienyl)isoxazole-3-carboxamide::N-(3-imidazol-1-ylpropyl)-5-thiophen-2-yl-1,2-oxazole-3-carboxamide::N-[3-(1-imidazolyl)propyl]-5-thiophen-2-yl-3-isoxazolecarboxamide::N-[3-(1H-imidazol-1-yl)propyl]-5-thien-2-ylisoxazole-3-carboxamide::SMR000023468::cid_3235911 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49229&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3235911 252629510 ZINC02497870 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238825 CCOC(=O)c1c(C)oc2c1cc(O)c1ccccc21 InChI=1S/C16H14O4/c1-3-19-16(18)14-9(2)20-15-11-7-5-4-6-10(11)13(17)8-12(14)15/h4-8,17H,3H2,1-2H3 NAYMIPUFIQUKOS-UHFFFAOYSA-N 114966 5-hydroxy-2-methyl-3-benzo[g]benzofurancarboxylic acid ethyl ester::5-hydroxy-2-methyl-benzo[g]benzofuran-3-carboxylic acid ethyl ester::MLS000090329::SMR000024939::cid_678599::ethyl 2-methyl-5-oxidanyl-benzo[g][1]benzofuran-3-carboxylate::ethyl 5-hydroxy-2-methylbenzo[g][1]benzofuran-3-carboxylate::ethyl 5-hydroxy-2-methylnaphtho[1,2-b]furan-3-carboxylate Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114966&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 678599 252664428 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238826 N(c1nc(cs1)-c1cccnc1)c1ccccn1 InChI=1S/C13H10N4S/c1-2-7-15-12(5-1)17-13-16-11(9-18-13)10-4-3-6-14-8-10/h1-9H,(H,15,16,17) YVFMRJIXHKPNTN-UHFFFAOYSA-N 50264070 CHEMBL492010::N-(4-(pyridin-3-yl)thiazol-2-yl)pyridin-2-amine::cid_704624 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 704624 104112192 CHEMBL492010 ZINC00088667 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238827 O=C(NCCc1ccccc1)c1cc(on1)-c1ccco1 InChI=1S/C16H14N2O3/c19-16(17-9-8-12-5-2-1-3-6-12)13-11-15(21-18-13)14-7-4-10-20-14/h1-7,10-11H,8-9H2,(H,17,19) KSWYOFGMLOJPMD-UHFFFAOYSA-N 114967 5-(2-furanyl)-N-(2-phenylethyl)-3-isoxazolecarboxamide::5-(2-furyl)-N-(2-phenylethyl)isoxazole-3-carboxamide::5-(2-furyl)-N-phenethyl-isoxazole-3-carboxamide::5-(furan-2-yl)-N-(2-phenylethyl)-1,2-oxazole-3-carboxamide::MLS000087198::SMR000023421::cid_3245765 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114967&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3245765 252664429 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238828 CCOC(=O)c1cnc(SCc2ccccc2)nc1N InChI=1S/C14H15N3O2S/c1-2-19-13(18)11-8-16-14(17-12(11)15)20-9-10-6-4-3-5-7-10/h3-8H,2,9H2,1H3,(H2,15,16,17) PMPWPSTVTPCAGQ-UHFFFAOYSA-N 49248 4-amino-2-(benzylthio)pyrimidine-5-carboxylic acid ethyl ester::4-amino-2-(phenylmethylthio)-5-pyrimidinecarboxylic acid ethyl ester::MLS000099282::SMR000073548::cid_251641::ethyl 4-amino-2-(benzylthio)-5-pyrimidinecarboxylate::ethyl 4-amino-2-benzylsulfanylpyrimidine-5-carboxylate::ethyl 4-azanyl-2-(phenylmethylsulfanyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49248&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 251641 252629529 ZINC00422101 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238829 COc1ccccc1-c1noc(n1)-c1ccco1 InChI=1S/C13H10N2O3/c1-16-10-6-3-2-5-9(10)12-14-13(18-15-12)11-7-4-8-17-11/h2-8H,1H3 OZGJXPIMHWRQIR-UHFFFAOYSA-N 114968 5-(2-furanyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole::5-(2-furyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole::5-(furan-2-yl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole::MLS000066686::SMR000082053::cid_1946188 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114968&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1946188 252664430 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238830 Cc1ccc(cc1)-c1nnc(Nc2ccccc2)[nH]1 InChI=1S/C15H14N4/c1-11-7-9-12(10-8-11)14-17-15(19-18-14)16-13-5-3-2-4-6-13/h2-10H,1H3,(H2,16,17,18,19) INDCVHFFYIEZRU-UHFFFAOYSA-N 49285 5-(4-methylphenyl)-N-phenyl-1H-1,2,4-triazol-3-amine::MLS000097050::SMR000075700::cid_2951125::phenyl-[5-(p-tolyl)-1H-1,2,4-triazol-3-yl]amine Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49285&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2951125 252629566 ZINC06492163 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238831 Clc1ccc(Nc2nc(cs2)-c2cccs2)nc1 InChI=1S/C12H8ClN3S2/c13-8-3-4-11(14-6-8)16-12-15-9(7-18-12)10-2-1-5-17-10/h1-7H,(H,14,15,16) OSWCDUQDLSLAGR-UHFFFAOYSA-N 49288 (5-chloro-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine::5-chloro-N-[4-(2-thienyl)-1,3-thiazol-2-yl]-2-pyridinamine::MLS000064746::N-(5-chloranylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::N-(5-chloro-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine::N-(5-chloropyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::SMR000077573::cid_2214576 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2214576 252629569 ZINC02861307 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238832 Clc1ccc(NC(=O)c2cc3ccccc3o2)nc1 InChI=1S/C14H9ClN2O2/c15-10-5-6-13(16-8-10)17-14(18)12-7-9-3-1-2-4-11(9)19-12/h1-8H,(H,16,17,18) HOLGMGFRFOWLGQ-UHFFFAOYSA-N 49299 MLS000061332::N-(5-chloranylpyridin-2-yl)-1-benzofuran-2-carboxamide::N-(5-chloro-2-pyridinyl)-1-benzofuran-2-carboxamide::N-(5-chloro-2-pyridinyl)-2-benzofurancarboxamide::N-(5-chloro-2-pyridyl)coumarilamide::N-(5-chloropyridin-2-yl)-1-benzofuran-2-carboxamide::SMR000070589::cid_673886 Oxysterols receptor LXR-beta 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 673886 252629580 ZINC00036086 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238833 Cc1cc(cs1)C(=O)NC1=NCCS1 InChI=1S/C9H10N2OS2/c1-6-4-7(5-14-6)8(12)11-9-10-2-3-13-9/h4-5H,2-3H2,1H3,(H,10,11,12) MESYCVOFSOUXRI-UHFFFAOYSA-N 114969 5-methyl-N-(2-thiazolin-2-yl)thiophene-3-carboxamide::MLS000065694::N-(4,5-dihydro-1,3-thiazol-2-yl)-5-methyl-3-thiophenecarboxamide::N-(4,5-dihydro-1,3-thiazol-2-yl)-5-methyl-thiophene-3-carboxamide::N-(4,5-dihydro-1,3-thiazol-2-yl)-5-methylthiophene-3-carboxamide::N-(4,5-dihydrothiazol-2-yl)-5-methyl-3-thiophenecarboxamide::SMR000080349::cid_1245366 Oxysterols receptor LXR-beta 67477 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114969&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1245366 252664431 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238834 COC(=O)C1C(C)Cc2[nH]c(C(=O)OC3CCCCC3)c(C)c2C1=O InChI=1S/C19H25NO5/c1-10-9-13-15(17(21)14(10)18(22)24-3)11(2)16(20-13)19(23)25-12-7-5-4-6-8-12/h10,12,14,20H,4-9H2,1-3H3 SOUPFDNQACDAQX-UHFFFAOYSA-N 44702 2-O-cyclohexyl 5-O-methyl 3,6-dimethyl-4-oxo-1,5,6,7-tetrahydroindole-2,5-dicarboxylate::3,6-dimethyl-4-oxo-1,5,6,7-tetrahydroindole-2,5-dicarboxylic acid O2-cyclohexyl ester O5-methyl ester::4-keto-3,6-dimethyl-1,5,6,7-tetrahydroindole-2,5-dicarboxylic acid O2-cyclohexyl ester O5-methyl ester::MLS000116516::O2-cyclohexyl O5-methyl 3,6-dimethyl-4-oxidanylidene-1,5,6,7-tetrahydroindole-2,5-dicarboxylate::SMR000093486::cid_2997361 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2997361 252625308 ZINC03215103 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238835 CC1CCC(CC1)OC(=O)c1[nH]c2CCCC(=O)c2c1C InChI=1S/C17H23NO3/c1-10-6-8-12(9-7-10)21-17(20)16-11(2)15-13(18-16)4-3-5-14(15)19/h10,12,18H,3-9H2,1-2H3 BJFBZCMAPVQWEQ-UHFFFAOYSA-N 44706 (4-methylcyclohexyl) 3-methyl-4-oxidanylidene-1,5,6,7-tetrahydroindole-2-carboxylate::(4-methylcyclohexyl) 3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylate::3-methyl-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester::4-keto-3-methyl-1,5,6,7-tetrahydroindole-2-carboxylic acid (4-methylcyclohexyl) ester::MLS000116534::SMR000093504::cid_2996853 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44706&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2996853 252625312 ZINC03344554 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238836 CCOC(=O)N1CCC(CC1)NC(=O)c1cc2ccccn2n1 InChI=1S/C16H20N4O3/c1-2-23-16(22)19-9-6-12(7-10-19)17-15(21)14-11-13-5-3-4-8-20(13)18-14/h3-5,8,11-12H,2,6-7,9-10H2,1H3,(H,17,21) YLNAAFSWYCZZKP-UHFFFAOYSA-N 114970 4-(pyrazolo[1,5-a]pyridine-2-carbonylamino)piperidine-1-carboxylic acid ethyl ester::4-[[oxo(2-pyrazolo[1,5-a]pyridinyl)methyl]amino]-1-piperidinecarboxylic acid ethyl ester::MLS000118411::SMR000095352::cid_5307919::ethyl 4-(pyrazolo[1,5-a]pyridin-2-ylcarbonylamino)piperidine-1-carboxylate::ethyl 4-(pyrazolo[1,5-a]pyridine-2-carbonylamino)piperidine-1-carboxylate Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114970&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5307919 252664432 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238837 Cc1nn(C(=O)c2cccs2)c(N)c1-c1ccccc1 InChI=1S/C15H13N3OS/c1-10-13(11-6-3-2-4-7-11)14(16)18(17-10)15(19)12-8-5-9-20-12/h2-9H,16H2,1H3 IWLLOIUNYLLJGP-UHFFFAOYSA-N 37176 (5-amino-3-methyl-4-phenyl-1-pyrazolyl)-thiophen-2-ylmethanone::(5-amino-3-methyl-4-phenyl-pyrazol-1-yl)-(2-thienyl)methanone::(5-amino-3-methyl-4-phenylpyrazol-1-yl)-thiophen-2-ylmethanone::(5-azanyl-3-methyl-4-phenyl-pyrazol-1-yl)-thiophen-2-yl-methanone::MLS000115895::SMR000092900::cid_1263277 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37176&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1263277 252618147 ZINC01075576 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238838 CC(C)Oc1cc(O)c2c(c1)occ(-c1ccc(O)cc1)c2=O InChI=1S/C18H16O5/c1-10(2)23-13-7-15(20)17-16(8-13)22-9-14(18(17)21)11-3-5-12(19)6-4-11/h3-10,19-20H,1-2H3 GBXSXYPMIFTYHI-UHFFFAOYSA-N 37183 3-(4-hydroxyphenyl)-5-oxidanyl-7-propan-2-yloxy-chromen-4-one::5-hydroxy-3-(4-hydroxyphenyl)-7-isopropoxy-chromone::5-hydroxy-3-(4-hydroxyphenyl)-7-propan-2-yloxy-1-benzopyran-4-one::5-hydroxy-3-(4-hydroxyphenyl)-7-propan-2-yloxychromen-4-one::MLS000115520::SMR000092610::cid_5308744 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37183&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5308744 252618154 ZINC05817431 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238839 CCOc1ccc2nc(NC(=O)Nc3cccs3)sc2c1 InChI=1S/C14H13N3O2S2/c1-2-19-9-5-6-10-11(8-9)21-14(15-10)17-13(18)16-12-4-3-7-20-12/h3-8H,2H2,1H3,(H2,15,16,17,18) JBLGCZDPPLPWSW-UHFFFAOYSA-N 37478 1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-(2-thienyl)urea::1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl-urea::1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-ylurea::MLS000119982::SMR000096899::cid_4101591 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37478&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4101591 252618449 ZINC02908206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238840 Cn1c(NC(=O)CCc2ccccc2)cc(=O)n(C)c1=O InChI=1S/C15H17N3O3/c1-17-12(10-14(20)18(2)15(17)21)16-13(19)9-8-11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3,(H,16,19) PWNLOMKLYXYKRC-UHFFFAOYSA-N 114971 MLS000103591::N-(1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)-3-phenylpropanamide::N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)-3-phenylpropanamide::N-(2,6-diketo-1,3-dimethyl-pyrimidin-4-yl)-3-phenyl-propionamide::N-[1,3-dimethyl-2,6-bis(oxidanylidene)pyrimidin-4-yl]-3-phenyl-propanamide::SMR000018868::cid_2148465 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114971&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2148465 252664433 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238841 CCS(=O)(=O)Nc1cc(ccc1C)-c1nc2cccnc2s1 InChI=1S/C15H15N3O2S2/c1-3-22(19,20)18-13-9-11(7-6-10(13)2)14-17-12-5-4-8-16-15(12)21-14/h4-9,18H,3H2,1-2H3 FUQNNFOLBVVFIR-UHFFFAOYSA-N 114972 MLS000102794::N-(2-methyl-5-thiazolo[5,4-b]pyridin-2-yl-phenyl)ethanesulfonamide::N-[2-methyl-5-(2-thiazolo[5,4-b]pyridinyl)phenyl]ethanesulfonamide::N-[2-methyl-5-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]ethanesulfonamide::SMR000018258::cid_5310341 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114972&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5310341 252664434 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238842 Cn1c(NC(=O)CCC2CCCCC2)cc(=O)n(C)c1=O InChI=1S/C15H23N3O3/c1-17-12(10-14(20)18(2)15(17)21)16-13(19)9-8-11-6-4-3-5-7-11/h10-11H,3-9H2,1-2H3,(H,16,19) YXMRLWJUDLJHQZ-UHFFFAOYSA-N 114973 3-cyclohexyl-N-(1,3-dimethyl-2,6-dioxo-4-pyrimidinyl)propanamide::3-cyclohexyl-N-(1,3-dimethyl-2,6-dioxopyrimidin-4-yl)propanamide::3-cyclohexyl-N-(2,6-diketo-1,3-dimethyl-pyrimidin-4-yl)propionamide::3-cyclohexyl-N-[1,3-dimethyl-2,6-bis(oxidanylidene)pyrimidin-4-yl]propanamide::MLS000103599::SMR000018874::cid_2148477 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114973&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2148477 252664435 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238843 CCCS(=O)(=O)NCc1cn2c(C)csc2n1 InChI=1S/C10H15N3O2S2/c1-3-4-17(14,15)11-5-9-6-13-8(2)7-16-10(13)12-9/h6-7,11H,3-5H2,1-2H3 KKSHWAITTSRIHM-UHFFFAOYSA-N 114974 MLS000102772::N-[(3-methyl-6-imidazo[2,1-b]thiazolyl)methyl]-1-propanesulfonamide::N-[(3-methylimidazo[2,1-b][1,3]thiazol-6-yl)methyl]propane-1-sulfonamide::N-[(3-methylimidazo[2,1-b]thiazol-6-yl)methyl]propane-1-sulfonamide::SMR000018213::cid_5310488 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114974&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5310488 252664436 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238844 CN(C)c1ccc(Nc2nc(cs2)-c2cccnc2)cc1 InChI=1S/C16H16N4S/c1-20(2)14-7-5-13(6-8-14)18-16-19-15(11-21-16)12-4-3-9-17-10-12/h3-11H,1-2H3,(H,18,19) VQQBVGGMFGFZPI-UHFFFAOYSA-N 33061 4-N,4-N-dimethyl-1-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine::MLS000108847::N4,N4-dimethyl-N1-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzene-1,4-diamine::N4,N4-dimethyl-N1-[4-(3-pyridinyl)-2-thiazolyl]benzene-1,4-diamine::SMR000104797::cid_704601::dimethyl-[4-[[4-(3-pyridyl)thiazol-2-yl]amino]phenyl]amine Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 704601 252616191 ZINC00088638 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238845 Clc1cccc(c1)-c1nnc(o1)-c1ccccc1 InChI=1S/C14H9ClN2O/c15-12-8-4-7-11(9-12)14-17-16-13(18-14)10-5-2-1-3-6-10/h1-9H HFKZYMPEMMAFOG-UHFFFAOYSA-N 48184 2-(3-chlorophenyl)-5-phenyl-1,3,4-oxadiazole::2-phenyl-5-(3-chlorophenyl)-1,3,4-oxadiazole (2d)::MLS000108072::SMR000104035::cid_259755 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48184&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 259755 252628481 ZINC00177082 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238846 CCOC(=O)C(=C/C=C1C=CN(CC=C)C=C1)\C#N InChI=1S/C15H16N2O2/c1-3-9-17-10-7-13(8-11-17)5-6-14(12-16)15(18)19-4-2/h3,5-8,10-11H,1,4,9H2,2H3/b14-6- YBLJJUJKZAXDPG-NSIKDUERSA-N 42978 (Z)-2-cyano-4-(1-prop-2-enyl-4-pyridinylidene)-2-butenoic acid ethyl ester::(Z)-4-(1-allyl-4-pyridylidene)-2-cyano-but-2-enoic acid ethyl ester::MLS000548178::SMR000113956::cid_6381056::ethyl (Z)-2-cyano-4-(1-prop-2-enylpyridin-4-ylidene)but-2-enoate::ethyl 4-(1-allyl-4(1H)-pyridinylidene)-2-cyano-2-butenoate Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42978&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6381056 252623666 ZINC13119733 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238847 Cc1nc2sc(nn2c(=O)c1Br)-c1ccccc1 InChI=1S/C12H8BrN3OS/c1-7-9(13)11(17)16-12(14-7)18-10(15-16)8-5-3-2-4-6-8/h2-6H,1H3 GUGVCERVYNWYFX-UHFFFAOYSA-N 114975 6-bromanyl-7-methyl-2-phenyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one::6-bromo-7-methyl-2-phenyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one::MLS000392047::SMR000102567::cid_792220 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114975&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 792220 252664437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238848 CCc1ccc2oc(nc2c1)-c1cccc(N)c1 InChI=1S/C15H14N2O/c1-2-10-6-7-14-13(8-10)17-15(18-14)11-4-3-5-12(16)9-11/h3-9H,2,16H2,1H3 CPAMZMMYEPRNLO-UHFFFAOYSA-N 48214 3-(5-Ethyl-benzooxazol-2-yl)-phenylamine::3-(5-ethyl-1,3-benzoxazol-2-yl)aniline::MLS000525240::SMR000122114::[3-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]amine::cid_735963 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48214&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 735963 252628511 ZINC00154721 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238849 CCOC(=O)c1cnc(SCCc2ccccc2)nc1N InChI=1S/C15H17N3O2S/c1-2-20-14(19)12-10-17-15(18-13(12)16)21-9-8-11-6-4-3-5-7-11/h3-7,10H,2,8-9H2,1H3,(H2,16,17,18) APNCRASUNSLSDH-UHFFFAOYSA-N 114976 4-Amino-2-phenethylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester::4-amino-2-(2-phenylethylthio)-5-pyrimidinecarboxylic acid ethyl ester::4-amino-2-(phenethylthio)pyrimidine-5-carboxylic acid ethyl ester::MLS000525438::SMR000122312::cid_864377::ethyl 4-amino-2-(2-phenylethylsulfanyl)pyrimidine-5-carboxylate::ethyl 4-azanyl-2-(2-phenylethylsulfanyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114976&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 864377 252664438 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238850 Cc1ccc(cc1)C(N)=NOC(=O)c1ccco1 InChI=1S/C13H12N2O3/c1-9-4-6-10(7-5-9)12(14)15-18-13(16)11-3-2-8-17-11/h2-8H,1H3,(H2,14,15) ZDEZEPUNRRREQN-UHFFFAOYSA-N 114977 2-furancarboxylic acid [(Z)-[amino-(4-methylphenyl)methylidene]amino] ester::MLS000548091::N'-(2-furoyloxy)-4-methylbenzenecarboximidamide::SMR000114333::[(Z)-[amino-(4-methylphenyl)methylidene]amino] furan-2-carboxylate::[(Z)-[azanyl-(4-methylphenyl)methylidene]amino] furan-2-carboxylate::cid_9549684::furan-2-carboxylic acid [(Z)-[amino(p-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114977&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9549684 252664439 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238851 Cc1cccc(c1)C(N)=NOC(=O)c1ccco1 InChI=1S/C13H12N2O3/c1-9-4-2-5-10(8-9)12(14)15-18-13(16)11-6-3-7-17-11/h2-8H,1H3,(H2,14,15) QKEPUYQNERUQSB-UHFFFAOYSA-N 114978 2-furancarboxylic acid [(Z)-[amino-(3-methylphenyl)methylidene]amino] ester::MLS000533507::N'-(2-furoyloxy)-3-methylbenzenecarboximidamide::SMR000140945::[(Z)-[amino-(3-methylphenyl)methylidene]amino] furan-2-carboxylate::[(Z)-[azanyl-(3-methylphenyl)methylidene]amino] furan-2-carboxylate::cid_5346031::furan-2-carboxylic acid [(Z)-[amino(m-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114978&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5346031 252664440 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238852 COc1cccc(c1)-c1nc2ccccc2s1 InChI=1S/C14H11NOS/c1-16-11-6-4-5-10(9-11)14-15-12-7-2-3-8-13(12)17-14/h2-9H,1H3 HROHCTACUYNNLZ-UHFFFAOYSA-N 49422 2-(3-methoxyphenyl)-1,3-benzothiazole::MLS000533667::SMR000141111::cid_833673 Oxysterols receptor LXR-beta 67479 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49422&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 833673 252629701 ZINC00359224 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238853 Cc1ccc(cc1C)N=CC(C#N)c1ccsc1 InChI=1S/C15H14N2S/c1-11-3-4-15(7-12(11)2)17-9-14(8-16)13-5-6-18-10-13/h3-7,9-10,14H,1-2H3 NNVITGHWPHCCAR-UHFFFAOYSA-N 49423 (E)-3-(3,4-dimethylanilino)-2-(3-thienyl)acrylonitrile::(E)-3-(3,4-dimethylanilino)-2-(3-thiophenyl)-2-propenenitrile::(E)-3-(3,4-dimethylanilino)-2-thiophen-3-ylprop-2-enenitrile::(E)-3-[(3,4-dimethylphenyl)amino]-2-thiophen-3-yl-prop-2-enenitrile::MLS000539447::SMR000125105::cid_2766393 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49423&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896797 252629702 ZINC03209983 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238854 COc1ccccc1-c1noc(n1)-c1cccs1 InChI=1S/C13H10N2O2S/c1-16-10-6-3-2-5-9(10)12-14-13(17-15-12)11-7-4-8-18-11/h2-8H,1H3 SVYWWEZMFNQJRZ-UHFFFAOYSA-N 114979 3-(2-methoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole::3-(2-methoxyphenyl)-5-thiophen-2-yl-1,2,4-oxadiazole::MLS000538854::SMR000144691::cid_1870209 Oxysterols receptor LXR-beta 67476 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114979&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1870209 252664441 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238855 Cc1cc(NC(=O)c2nn3cccnc3c2Cl)no1 InChI=1S/C11H8ClN5O2/c1-6-5-7(16-19-6)14-11(18)9-8(12)10-13-3-2-4-17(10)15-9/h2-5H,1H3,(H,14,16,18) ODSJDGAPXJATKT-UHFFFAOYSA-N 114980 3-chloranyl-N-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide::3-chloro-N-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide::3-chloro-N-(5-methyl-3-isoxazolyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide::3-chloro-N-(5-methyl-3-isoxazolyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide::3-chloro-N-(5-methylisoxazol-3-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide::MLS000538609::SMR000144646::cid_1256890 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114980&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1256890 252664442 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238856 Cc1nnc(SCC(=O)Nc2nsc(n2)-c2ccc(cc2)C(C)(C)C)s1 InChI=1S/C17H19N5OS3/c1-10-20-21-16(25-10)24-9-13(23)18-15-19-14(26-22-15)11-5-7-12(8-6-11)17(2,3)4/h5-8H,9H2,1-4H3,(H,18,22,23) WJGRHTNRJDYYMY-UHFFFAOYSA-N 114981 MLS000522293::N-[5-(4-tert-butylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetamide::N-[5-(4-tert-butylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]ethanamide::N-[5-(4-tert-butylphenyl)-1,2,4-thiadiazol-3-yl]-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]acetamide::SMR000127561::cid_3527790 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114981&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3527790 252664443 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238857 Clc1ccc(CSc2nc3ccncc3[nH]2)cc1 InChI=1S/C13H10ClN3S/c14-10-3-1-9(2-4-10)8-18-13-16-11-5-6-15-7-12(11)17-13/h1-7H,8H2,(H,16,17) LSMGUBAANPNITB-UHFFFAOYSA-N 49439 2-[(4-chlorobenzyl)thio]-3H-imidazo[4,5-c]pyridine::2-[(4-chlorophenyl)methylsulfanyl]-3H-imidazo[4,5-c]pyridine::2-[(4-chlorophenyl)methylthio]-3H-imidazo[4,5-c]pyridine::MLS000522716::SMR000127983::cid_9551354 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49439&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9551354 252629717 ZINC08828536 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238858 CC(=Nc1ccccc1)c1sc2ccccc2c1O InChI=1S/C16H13NOS/c1-11(17-12-7-3-2-4-8-12)16-15(18)13-9-5-6-10-14(13)19-16/h2-10,18H,1H3 OWBIXPDECLROKM-UHFFFAOYSA-N 49454 (2Z)-2-(1-anilinoethylidene)-1-benzothiophen-3-one::(2Z)-2-(1-anilinoethylidene)benzothiophen-3-one::(2Z)-2-(1-phenylazanylethylidene)-1-benzothiophen-3-one::2-[1-Phenylamino-eth-(Z)-ylidene]-benzo[b]thiophen-3-one::MLS000550925::SMR000145053::cid_5399972 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49454&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5399972 252629731 ZINC19940244 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238859 CC(=Nc1cccc(C)c1)c1sc2ccccc2c1O InChI=1S/C17H15NOS/c1-11-6-5-7-13(10-11)18-12(2)17-16(19)14-8-3-4-9-15(14)20-17/h3-10,19H,1-2H3 WDGGDHCOGSHKMB-UHFFFAOYSA-N 49455 (2Z)-2-[1-(3-methylanilino)ethylidene]-1-benzothiophen-3-one::(2Z)-2-[1-(m-toluidino)ethylidene]benzothiophen-3-one::(2Z)-2-[1-[(3-methylphenyl)amino]ethylidene]-1-benzothiophen-3-one::2-[1-m-Tolylamino-eth-(Z)-ylidene]-benzo[b]thiophen-3-one::MLS000550927::SMR000145055::cid_6859005 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49455&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6859005 252629732 ZINC13471367 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238860 CC(C)c1cc([nH]n1)C(=O)NN=C(C)c1cccs1 InChI=1S/C13H16N4OS/c1-8(2)10-7-11(16-15-10)13(18)17-14-9(3)12-5-4-6-19-12/h4-8H,1-3H3,(H,15,16)(H,17,18) BWBUORCJHAHWOT-UHFFFAOYSA-N 114982 5-Isopropyl-2H-pyrazole-3-carboxylic acid [1-thiophen-2-yl-eth-(Z)-ylidene]-hydrazide::5-isopropyl-N-[(Z)-1-(2-thienyl)ethylideneamino]-1H-pyrazole-3-carboxamide::5-propan-2-yl-N-[(Z)-1-thiophen-2-ylethylideneamino]-1H-pyrazole-3-carboxamide::MLS000556493::SMR000147810::cid_5782679 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114982&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5782679 252664444 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238861 CCOC(=O)c1sc2nc3CC(C)(CC)OCc3cc2c1N InChI=1S/C16H20N2O3S/c1-4-16(3)7-11-9(8-21-16)6-10-12(17)13(15(19)20-5-2)22-14(10)18-11/h6H,4-5,7-8,17H2,1-3H3 OQOQNULQSFFCLL-UHFFFAOYSA-N 49464 3-Amino-7-ethyl-7-methyl-7,8-dihydro-5H-pyrano[4,3-b]thieno[3,2-e]pyridine-2-carboxylic acid ethyl ester::MLS000557283::SMR000148200::cid_3421545 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49464&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3421545 242053132 ZINC00524961 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238862 Cc1nc(N)sc1N=Nc1ccc(Br)cc1 InChI=1S/C10H9BrN4S/c1-6-9(16-10(12)13-6)15-14-8-4-2-7(11)3-5-8/h2-5H,1H3,(H2,12,13) CLMHKUIJZLOVDX-UHFFFAOYSA-N 49467 (4-bromophenyl)-[(Z)-(2-imino-4-methyl-3-thiazolin-5-ylidene)amino]amine::4-bromo-N-[(Z)-(2-imino-4-methyl-1,3-thiazol-5-ylidene)amino]aniline::4-bromo-N-[(Z)-(2-imino-4-methyl-5-thiazolylidene)amino]aniline::MLS000564283::N-[(Z)-(2-azanylidene-4-methyl-1,3-thiazol-5-ylidene)amino]-4-bromanyl-aniline::SMR000151833::cid_9551866 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49467&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9551866 252629743 ZINC13110703 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238863 Cc1cccc(NC(=O)c2ccc3ccccc3n2)c1C InChI=1S/C18H16N2O/c1-12-6-5-9-15(13(12)2)20-18(21)17-11-10-14-7-3-4-8-16(14)19-17/h3-11H,1-2H3,(H,20,21) IBFFDAXZKQDQLD-UHFFFAOYSA-N 49470 MLS000569762::N-(2,3-dimethylphenyl)-2-quinolinecarboxamide::N-(2,3-dimethylphenyl)quinaldamide::N-(2,3-dimethylphenyl)quinoline-2-carboxamide::SMR000155229::cid_2116521 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49470&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2116521 252629746 ZINC02653136 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238864 O=C(CCCC(=O)N(CC(=O)NC1CCCC1)C1CCCC1)Nc1ccccn1 InChI=1S/C22H32N4O3/c27-20(25-19-12-5-6-15-23-19)13-7-14-22(29)26(18-10-3-4-11-18)16-21(28)24-17-8-1-2-9-17/h5-6,12,15,17-18H,1-4,7-11,13-14,16H2,(H,24,28)(H,23,25,27) WUNZIMUNMRLMRA-UHFFFAOYSA-N 51792 MLS000072836::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-keto-ethyl]-N-(2-pyridyl)glutaramide::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-pyridin-2-yl-pentanediamide::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-oxoethyl]-N-(2-pyridinyl)pentanediamide::N'-cyclopentyl-N'-[2-(cyclopentylamino)-2-oxoethyl]-N-pyridin-2-ylpentanediamide::Pentanedioic acid cyclopentyl-cyclopentylcarbamoylmethyl-amide pyridin-2-ylamide::SMR000004293::cid_650348 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51792&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 650348 252631971 ZINC18036714 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238865 Nc1nc(Nc2ccc(Cl)cc2)nc2ccccc12 InChI=1S/C14H11ClN4/c15-9-5-7-10(8-6-9)17-14-18-12-4-2-1-3-11(12)13(16)19-14/h1-8H,(H3,16,17,18,19) WXPPDLYBIBDKHZ-UHFFFAOYSA-N 44548 (4-aminoquinazolin-2-yl)-(4-chlorophenyl)amine;hydrochloride::2-N-(4-chlorophenyl)quinazoline-2,4-diamine;hydrochloride::MLS000536850::N2-(4-chlorophenyl)quinazoline-2,4-diamine;hydrochloride::N~2~-(4-chlorophenyl)-2,4-quinazolinediamine hydrochloride::SMR000143487::cid_2953146 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44548&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 962704 252625159 ZINC03328762 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238866 Cc1ccc(cc1)S(=O)(=O)NC(=NC(=S)Nc1ccccc1)c1ccccc1 InChI=1S/C21H19N3O2S2/c1-16-12-14-19(15-13-16)28(25,26)24-20(17-8-4-2-5-9-17)23-21(27)22-18-10-6-3-7-11-18/h2-15H,1H3,(H2,22,23,24,27) KGQQJVZZQBFORJ-UHFFFAOYSA-N 49482 1-[(E)-(4-methylphenyl)sulfonylimino-phenylmethyl]-3-phenylthiourea::1-[(E)-N-(4-methylphenyl)sulfonyl-C-phenyl-carbonimidoyl]-3-phenyl-thiourea::1-[(E)-N-(4-methylphenyl)sulfonyl-C-phenylcarbonimidoyl]-3-phenylthiourea::1-phenyl-3-[(E)-C-phenyl-N-tosyl-carbonimidoyl]thiourea::MLS000570232::SMR000150341::cid_6306769 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49482&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6306769 252629758 ZINC13482078 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238867 O=c1n(ncc2ccccc12)-c1ccc2ccccc2c1 InChI=1S/C18H12N2O/c21-18-17-8-4-3-7-15(17)12-19-20(18)16-10-9-13-5-1-2-6-14(13)11-16/h1-12H FSLCVBMZDHZDKO-UHFFFAOYSA-N 114983 2-(2-naphthalenyl)-1-phthalazinone::2-(2-naphthyl)phthalazin-1-one::2-naphthalen-2-ylphthalazin-1-one::MLS000565163::SMR000152430::cid_730347 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114983&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 730347 252664445 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238868 Cc1ccsc1C=NNC(=O)c1sccc1C InChI=1S/C12H12N2OS2/c1-8-3-5-16-10(8)7-13-14-12(15)11-9(2)4-6-17-11/h3-7H,1-2H3,(H,14,15) ASVULYVVYQJTBX-UHFFFAOYSA-N 114984 3-methyl-N'-[(3-methyl-2-thienyl)methylene]-2-thiophenecarbohydrazide::3-methyl-N-[(E)-(3-methyl-2-thienyl)methyleneamino]thiophene-2-carboxamide::3-methyl-N-[(E)-(3-methyl-2-thiophenyl)methylideneamino]-2-thiophenecarboxamide::3-methyl-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]thiophene-2-carboxamide::MLS000325445::SMR000159522::cid_6873509 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114984&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6873509 252664446 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238869 [O-][N+](=O)c1cccnc1NCCNc1ncc(cc1Cl)C(F)(F)F InChI=1S/C13H11ClF3N5O2/c14-9-6-8(13(15,16)17)7-21-11(9)19-4-5-20-12-10(22(23)24)2-1-3-18-12/h1-3,6-7H,4-5H2,(H,18,20)(H,19,21) ZVZGCHWOUJKNOM-UHFFFAOYSA-N 76427 MLS000326042::N'-[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]-N-(3-nitropyridin-2-yl)ethane-1,2-diamine::N'-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3-nitro-2-pyridinyl)ethane-1,2-diamine::N'-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-nitropyridin-2-yl)ethane-1,2-diamine::N~1~-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N~2~-(3-nitro-2-pyridinyl)-1,2-ethanediamine::SMR000170132::[3-chloro-5-(trifluoromethyl)-2-pyridyl]-[2-[(3-nitro-2-pyridyl)amino]ethyl]amine::cid_3773884 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76427&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3773884 252653606 ZINC20366010 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238870 FC(F)(F)c1cc(Cl)c2nc(cn2c1)-c1ccccc1 InChI=1S/C14H8ClF3N2/c15-11-6-10(14(16,17)18)7-20-8-12(19-13(11)20)9-4-2-1-3-5-9/h1-8H ATHNSQRFCXRPMB-UHFFFAOYSA-N 49504 8-chloranyl-2-phenyl-6-(trifluoromethyl)imidazo[1,2-a]pyridine::8-chloro-2-phenyl-6-(trifluoromethyl)imidazo[1,2-a]pyridine::MLS000327118::SMR000179717::cid_2725829 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49504&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2725829 252629780 ZINC00074217 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238871 Cc1cccc(c1)C(N)=NOC(=O)c1cccs1 InChI=1S/C13H12N2O2S/c1-9-4-2-5-10(8-9)12(14)15-17-13(16)11-6-3-7-18-11/h2-8H,1H3,(H2,14,15) XRPVRHOSGACNPK-UHFFFAOYSA-N 114985 2-thiophenecarboxylic acid [(Z)-[amino-(3-methylphenyl)methylidene]amino] ester::MLS000553241::SMR000176880::[(Z)-[amino-(3-methylphenyl)methylidene]amino] thiophene-2-carboxylate::[(Z)-[azanyl-(3-methylphenyl)methylidene]amino] thiophene-2-carboxylate::cid_9586568::thiophene-2-carboxylic acid [(Z)-[amino(m-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114985&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9586568 252664447 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238872 CCNC(=S)NNC(=O)c1cc(nc2ccccc12)-c1ccc(OCC)cc1 InChI=1S/C21H22N4O2S/c1-3-22-21(28)25-24-20(26)17-13-19(23-18-8-6-5-7-16(17)18)14-9-11-15(12-10-14)27-4-2/h5-13H,3-4H2,1-2H3,(H,24,26)(H2,22,25,28) OUMOCZYTTNFGNH-UHFFFAOYSA-N 49511 1-[[2-(4-ethoxyphenyl)quinolin-4-yl]carbonylamino]-3-ethyl-thiourea::1-[[2-(4-ethoxyphenyl)quinoline-4-carbonyl]amino]-3-ethylthiourea::1-[[[2-(4-ethoxyphenyl)-4-quinolinyl]-oxomethyl]amino]-3-ethylthiourea::1-ethyl-3-[(2-p-phenetylquinoline-4-carbonyl)amino]thiourea::2-{[2-(4-ethoxyphenyl)-4-quinolinyl]carbonyl}-N-ethylhydrazinecarbothioamide::MLS000545499::SMR000160210::cid_1767610 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49511&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1767610 252629787 ZINC08681131 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238873 C(Cc1ccccc1)Sc1nccn1-c1ccccc1 InChI=1S/C17H16N2S/c1-3-7-15(8-4-1)11-14-20-17-18-12-13-19(17)16-9-5-2-6-10-16/h1-10,12-13H,11,14H2 VARJAHYAMWUYFI-UHFFFAOYSA-N 114986 1-phenyl-2-(2-phenylethylsulfanyl)imidazole::1-phenyl-2-(2-phenylethylthio)imidazole::2-(phenethylsulfanyl)-1-phenyl-1H-imidazole::2-(phenethylthio)-1-phenyl-imidazole::MLS000327196::SMR000179805::cid_1477534 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114986&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1477534 252664448 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238874 Clc1ccc(cc1)-c1ccc(o1)C(=S)N1CCCCC1 InChI=1S/C16H16ClNOS/c17-13-6-4-12(5-7-13)14-8-9-15(19-14)16(20)18-10-2-1-3-11-18/h4-9H,1-3,10-11H2 OBWNESFOIWOSHR-UHFFFAOYSA-N 114987 1-{[5-(4-chlorophenyl)-2-furyl]carbonothioyl}piperidine::MLS000571391::SMR000193476::[5-(4-chlorophenyl)-2-furanyl]-(1-piperidinyl)methanethione::[5-(4-chlorophenyl)-2-furyl]-piperidino-methanethione::[5-(4-chlorophenyl)furan-2-yl]-piperidin-1-yl-methanethione::[5-(4-chlorophenyl)furan-2-yl]-piperidin-1-ylmethanethione::cid_796821 Oxysterols receptor LXR-beta 67497 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114987&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 796821 252664449 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238875 Nc1c2CCCCCc2nc2sc3CCCCc3c12 InChI=1S/C16H20N2S/c17-15-10-6-2-1-3-8-12(10)18-16-14(15)11-7-4-5-9-13(11)19-16/h1-9H2,(H2,17,18) INQNGSMMHYFCSF-UHFFFAOYSA-N 114988 2,3,4,7,8,9,10,11-octahydro-1H-[1]benzothieno[2,3-b]cyclohepta[e]pyridin-12-amine::MLS000570484::SMR000186910::cid_744115 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114988&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 744115 242053908 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238876 CCc1ccc(cc1)C1CC(=NN1S(C)(=O)=O)c1ccco1 InChI=1S/C16H18N2O3S/c1-3-12-6-8-13(9-7-12)15-11-14(16-5-4-10-21-16)17-18(15)22(2,19)20/h4-10,15H,3,11H2,1-2H3 OAOCQEHAIHFWPC-UHFFFAOYSA-N 114989 3-(4-ethylphenyl)-5-(2-furanyl)-2-methylsulfonyl-3,4-dihydropyrazole::3-(4-ethylphenyl)-5-(furan-2-yl)-2-methylsulfonyl-3,4-dihydropyrazole::5-(4-ethylphenyl)-3-(2-furyl)-1-(methylsulfonyl)-4,5-dihydro-1H-pyrazole::5-(4-ethylphenyl)-3-(2-furyl)-1-mesyl-2-pyrazoline::MLS000580616::SMR000199505::cid_2951757 Oxysterols receptor LXR-beta 67528 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114989&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2951757 252664450 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238877 O=C(NN=Cc1cccs1)c1[nH]nc2CCCc12 InChI=1S/C12H12N4OS/c17-12(16-13-7-8-3-2-6-18-8)11-9-4-1-5-10(9)14-15-11/h2-3,6-7H,1,4-5H2,(H,14,15)(H,16,17) RHTNOJVNXRSZGT-UHFFFAOYSA-N 114990 MLS000576863::N'-(2-thienylmethylene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide::N-[(E)-2-thenylideneamino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide::N-[(E)-thiophen-2-ylmethylideneamino]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxamide::SMR000185339::cid_5720643 Oxysterols receptor LXR-beta 67519 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114990&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5720643 252664451 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238878 Cc1ccnc(NC(=O)\C=C\c2cccs2)c1 InChI=1S/C13H12N2OS/c1-10-6-7-14-12(9-10)15-13(16)5-4-11-3-2-8-17-11/h2-9H,1H3,(H,14,15,16)/b5-4+ YVGHONIDDFLTOD-SNAWJCMRSA-N 114991 (E)-N-(4-methyl-2-pyridinyl)-3-thiophen-2-yl-2-propenamide::(E)-N-(4-methyl-2-pyridyl)-3-(2-thienyl)acrylamide::(E)-N-(4-methylpyridin-2-yl)-3-thiophen-2-yl-prop-2-enamide::(E)-N-(4-methylpyridin-2-yl)-3-thiophen-2-ylprop-2-enamide::MLS000578251::N-(4-methyl-2-pyridinyl)-3-(2-thienyl)acrylamide::SMR000197660::cid_845032 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114991&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 845032 252664452 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238879 Cc1n[nH]c(Nc2cccc(C)c2)c1[N+]([O-])=O InChI=1S/C11H12N4O2/c1-7-4-3-5-9(6-7)12-11-10(15(16)17)8(2)13-14-11/h3-6H,1-2H3,(H2,12,13,14) WTPOMZKVZLWDAL-UHFFFAOYSA-N 43701 (5-Methyl-4-nitro-2H-pyrazol-3-yl)-m-tolyl-amine::(5-methyl-4-nitro-1H-pyrazol-3-yl)-(m-tolyl)amine::5-methyl-N-(3-methylphenyl)-4-nitro-1H-pyrazol-3-amine::MLS000569061::SMR000176283::cid_3122354 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43701&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3122354 252624377 ZINC13151805 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238880 Cc1c(csc1-c1ccccc1)C(=O)Nc1ccccc1 InChI=1S/C18H15NOS/c1-13-16(18(20)19-15-10-6-3-7-11-15)12-21-17(13)14-8-4-2-5-9-14/h2-12H,1H3,(H,19,20) PRNOOINXYPYYPJ-UHFFFAOYSA-N 76463 4-Methyl-5-phenyl-thiophene-3-carboxylic acid phenylamide::4-methyl-N,5-diphenyl-3-thiophenecarboxamide::4-methyl-N,5-diphenyl-thiophene-3-carboxamide::4-methyl-N,5-diphenylthiophene-3-carboxamide::MLS000564604::SMR000177122::cid_829294 Oxysterols receptor LXR-beta 67516 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76463&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 829294 252653641 ZINC00351154 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238881 O=C1\C(Sc2ccc3ccccc3c12)=C/c1cccs1 InChI=1S/C17H10OS2/c18-17-15(10-12-5-3-9-19-12)20-14-8-7-11-4-1-2-6-13(11)16(14)17/h1-10H/b15-10+ NYRSOTAWRKGABU-XNTDXEJSSA-N 114852 (2E)-2-(2-thenylidene)benzo[e]benzothiophen-1-one::(2E)-2-(thien-2-ylmethylene)naphtho[2,1-b]thiophen-1(2H)-one::(2E)-2-(thiophen-2-ylmethylidene)-1-benzo[e][1]benzothiolone::(2E)-2-(thiophen-2-ylmethylidene)benzo[e][1]benzothiol-1-one::MLS000584663::SMR000203626::cid_12004806 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114852&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 12004806 252664320 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238882 Cc1ccc(cc1)C(N)=NOC(=O)c1cccs1 InChI=1S/C13H12N2O2S/c1-9-4-6-10(7-5-9)12(14)15-17-13(16)11-3-2-8-18-11/h2-8H,1H3,(H2,14,15) NRSOGUSQGSRUCP-UHFFFAOYSA-N 114992 2-thiophenecarboxylic acid [(Z)-[amino-(4-methylphenyl)methylidene]amino] ester::4-methyl-N'-[(thien-2-ylcarbonyl)oxy]benzenecarboximidamide::MLS000585209::SMR000203972::[(Z)-[amino-(4-methylphenyl)methylidene]amino] thiophene-2-carboxylate::[(Z)-[azanyl-(4-methylphenyl)methylidene]amino] thiophene-2-carboxylate::cid_9666663::thiophene-2-carboxylic acid [(Z)-[amino(p-tolyl)methylene]amino] ester Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9666663 252664453 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238883 Cc1cc(O)n(c1O)-c1ccc(NCc2ccc(Cl)cc2)c(c1)[N+]([O-])=O InChI=1S/C18H16ClN3O4/c1-11-8-17(23)21(18(11)24)14-6-7-15(16(9-14)22(25)26)20-10-12-2-4-13(19)5-3-12/h2-9,20,23-24H,10H2,1H3 DVKRIRMDNXYYMV-UHFFFAOYSA-N 83558 1-[4-[(4-chlorobenzyl)amino]-3-nitro-phenyl]-3-methyl-pyrrolidine-2,5-quinone::1-[4-[(4-chlorophenyl)methylamino]-3-nitro-phenyl]-3-methyl-pyrrolidine-2,5-dione::1-[4-[(4-chlorophenyl)methylamino]-3-nitrophenyl]-3-methylpyrrolidine-2,5-dione::1-{4-[(4-chlorobenzyl)amino]-3-nitrophenyl}-3-methylpyrrolidine-2,5-dione::MLS000584616::SMR000207201::cid_12005260 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83558&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91898509 252658745 ZINC13122032 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238884 N=C1N(CC(=O)c2ccccc2)Cc2ccccc12 InChI=1S/C16H14N2O/c17-16-14-9-5-4-8-13(14)10-18(16)11-15(19)12-6-2-1-3-7-12/h1-9,17H,10-11H2 GMXDICRNXLEYQM-UHFFFAOYSA-N 114993 2-(1-Imino-1,3-dihydro-isoindol-2-yl)-1-phenyl-ethanone::2-(1-iminoisoindolin-2-yl)-1-phenyl-ethanone;hydrochloride::2-(3-azanylidene-1H-isoindol-2-yl)-1-phenyl-ethanone;hydrochloride::2-(3-imino-1H-isoindol-2-yl)-1-phenylethanone;hydrochloride::MLS000587574::SMR000211541::cid_12005557 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 682597 252664454 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238885 Clc1ccccc1Nc1nnc(s1)-c1ccncc1 InChI=1S/C13H9ClN4S/c14-10-3-1-2-4-11(10)16-13-18-17-12(19-13)9-5-7-15-8-6-9/h1-8H,(H,16,18) KYLJEAUZXBZHNF-UHFFFAOYSA-N 78207 (2-Chloro-phenyl)-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-amine::(2-chlorophenyl)-[5-(4-pyridyl)-1,3,4-thiadiazol-2-yl]amine::MLS000331918::N-(2-chlorophenyl)-5-pyridin-4-yl-1,3,4-thiadiazol-2-amine::SMR000221404::cid_1952758 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78207&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1952758 252654968 ZINC02339055 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238886 CC1=CN2C(S1)=NC(=O)\C(=C/c1ccco1)C2=N InChI=1S/C12H9N3O2S/c1-7-6-15-10(13)9(5-8-3-2-4-17-8)11(16)14-12(15)18-7/h2-6,13H,1H3/b9-5-,13-10? QNEHKBLPIIBDAT-NYADUSNBSA-N 49614 (6Z)-5-azanylidene-6-(furan-2-ylmethylidene)-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one::(6Z)-6-(2-furanylmethylidene)-5-imino-2-methyl-7-thiazolo[3,2-a]pyrimidinone::(6Z)-6-(2-furfurylidene)-5-imino-2-methyl-thiazolo[3,2-a]pyrimidin-7-one::(6Z)-6-(furan-2-ylmethylidene)-5-imino-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one::6-[1-Furan-2-yl-meth-(Z)-ylidene]-5-imino-2-methyl-5,6-dihydro-thiazolo[3,2-a]pyrimidin-7-one::MLS000580241::SMR000220510::cid_1779857 Oxysterols receptor LXR-beta 67489 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49614&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1779857 252629889 ZINC59837599 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238887 Cc1ccc(\C=N\NC(=O)c2ccccn2)s1 InChI=1S/C12H11N3OS/c1-9-5-6-10(17-9)8-14-15-12(16)11-4-2-3-7-13-11/h2-8H,1H3,(H,15,16)/b14-8+ MMKIBXLZUXTSKE-RIYZIHGNSA-N 114994 MLS000589024::N-[(E)-(5-methyl-2-thienyl)methyleneamino]picolinamide::N-[(E)-(5-methyl-2-thiophenyl)methylideneamino]-2-pyridinecarboxamide::N-[(E)-(5-methylthiophen-2-yl)methylideneamino]pyridine-2-carboxamide::Pyridine-2-carboxylic acid [1-(5-methyl-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide::SMR000219653::cid_6878933 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114994&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6878933 252664455 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238888 Cc1ccc(\C=N\NC(=O)c2ccoc2C)s1 InChI=1S/C12H12N2O2S/c1-8-3-4-10(17-8)7-13-14-12(15)11-5-6-16-9(11)2/h3-7H,1-2H3,(H,14,15)/b13-7+ XVROMXHMMIUPRJ-NTUHNPAUSA-N 114995 2-Methyl-furan-3-carboxylic acid [1-(5-methyl-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide::2-methyl-N-[(E)-(5-methyl-2-thienyl)methyleneamino]-3-furamide::2-methyl-N-[(E)-(5-methyl-2-thiophenyl)methylideneamino]-3-furancarboxamide::2-methyl-N-[(E)-(5-methylthiophen-2-yl)methylideneamino]furan-3-carboxamide::MLS000591098::SMR000217916::cid_6886797 Oxysterols receptor LXR-beta 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114995&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6886797 252664456 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238889 C(Sc1ccc(nn1)-c1cccs1)c1ccccc1 InChI=1S/C15H12N2S2/c1-2-5-12(6-3-1)11-19-15-9-8-13(16-17-15)14-7-4-10-18-14/h1-10H,11H2 ALXJYDIYDDOWBL-UHFFFAOYSA-N 114996 3-(benzylthio)-6-(2-thienyl)pyridazine::3-(phenylmethylsulfanyl)-6-thiophen-2-yl-pyridazine::3-(phenylmethylthio)-6-thiophen-2-ylpyridazine::3-benzylsulfanyl-6-thiophen-2-ylpyridazine::MLS000696686::SMR000237137::cid_6624149 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114996&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6624149 252664457 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238890 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)OCC(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2s1 InChI=1S/C27H27N3O5S2/c1-4-30(5-2)37(33,34)22-13-9-20(10-14-22)27(32)35-17-25(31)28-21-11-7-19(8-12-21)26-29-23-15-6-18(3)16-24(23)36-26/h6-16H,4-5,17H2,1-3H3,(H,28,31) PGGQXUGPYJVIRG-UHFFFAOYSA-N 96095 4-(diethylsulfamoyl)benzoic acid [2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] ester::4-(diethylsulfamoyl)benzoic acid [2-keto-2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]ethyl] ester::MLS000395044::SMR000248410::[2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] 4-(diethylsulfamoyl)benzoate::[2-[[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]amino]-2-oxidanylidene-ethyl] 4-(diethylsulfamoyl)benzoate::cid_2353548 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96095&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2353548 164037339 ZINC03235724 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238892 Cc1nn(c(C)c1Br)-c1nnc(NC2CCCCC2)nn1 InChI=1S/C13H18BrN7/c1-8-11(14)9(2)21(20-8)13-18-16-12(17-19-13)15-10-6-4-3-5-7-10/h10H,3-7H2,1-2H3,(H,15,16,17) VIWOUODEFPGMBW-UHFFFAOYSA-N 114998 6-(4-bromanyl-3,5-dimethyl-pyrazol-1-yl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine::6-(4-bromo-3,5-dimethyl-1-pyrazolyl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine::6-(4-bromo-3,5-dimethylpyrazol-1-yl)-N-cyclohexyl-1,2,4,5-tetrazin-3-amine::MLS000702666::N-[6-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetraazin-3-yl]-N-cyclohexylamine::SMR000225861::[6-(4-bromo-3,5-dimethyl-pyrazol-1-yl)-1,2,4,5-tetrazin-3-yl]-cyclohexyl-amine::cid_5113181 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114998&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5113181 252664459 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238893 Cc1ccc(\C=N\N=C\c2ccc(C)s2)s1 InChI=1S/C12H12N2S2/c1-9-3-5-11(15-9)7-13-14-8-12-6-4-10(2)16-12/h3-8H,1-2H3/b13-7+,14-8+ QXERRTVWENUEGZ-FNCQTZNRSA-N 114999 (E)-(5-methyl-2-thienyl)methylene-[(E)-(5-methyl-2-thienyl)methyleneamino]amine::(E)-1-(5-methyl-2-thiophenyl)-N-[(E)-(5-methyl-2-thiophenyl)methylideneamino]methanimine::(E)-1-(5-methylthiophen-2-yl)-N-[(E)-(5-methylthiophen-2-yl)methylideneamino]methanimine::5-methyl-2-thiophenecarbaldehyde [(5-methyl-2-thienyl)methylene]hydrazone::MLS000702008::SMR000228632::cid_6875563 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114999&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6875563 252664460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238894 Cc1cc(C(=O)NC2CCCCC2)c(C)n1-c1ccc(F)cc1 InChI=1S/C19H23FN2O/c1-13-12-18(19(23)21-16-6-4-3-5-7-16)14(2)22(13)17-10-8-15(20)9-11-17/h8-12,16H,3-7H2,1-2H3,(H,21,23) GHKAEQQTNJGAAS-UHFFFAOYSA-N 115000 MLS000335592::N-cyclohexyl-1-(4-fluorophenyl)-2,5-dimethyl-3-pyrrolecarboxamide::N-cyclohexyl-1-(4-fluorophenyl)-2,5-dimethyl-pyrrole-3-carboxamide::N-cyclohexyl-1-(4-fluorophenyl)-2,5-dimethylpyrrole-3-carboxamide::SMR000253346::cid_3881988 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115000&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3881988 252664461 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238895 COCCNc1nc(cs1)-c1cc2ccccc2o1 InChI=1S/C14H14N2O2S/c1-17-7-6-15-14-16-11(9-19-14)13-8-10-4-2-3-5-12(10)18-13/h2-5,8-9H,6-7H2,1H3,(H,15,16) AAQZGOOBPBBYOB-UHFFFAOYSA-N 49665 4-(1-benzofuran-2-yl)-N-(2-methoxyethyl)-1,3-thiazol-2-amine::4-(2-benzofuranyl)-N-(2-methoxyethyl)-2-thiazolamine::MLS000388876::SMR000255049::[4-(benzofuran-2-yl)thiazol-2-yl]-(2-methoxyethyl)amine::cid_2469776 Oxysterols receptor LXR-beta 67528 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49665&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2469776 252629940 ZINC03352664 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238896 Fc1ccccc1SCn1nnc2ccccc2c1=O InChI=1S/C14H10FN3OS/c15-11-6-2-4-8-13(11)20-9-18-14(19)10-5-1-3-7-12(10)16-17-18/h1-8H,9H2 VVFGFLFZBRPQFD-UHFFFAOYSA-N 115001 3-[(2-fluorophenyl)sulfanylmethyl]-1,2,3-benzotriazin-4-one::3-[[(2-fluorophenyl)thio]methyl]-1,2,3-benzotriazin-4-one::MLS000388902::SMR000255075::cid_2591914 Oxysterols receptor LXR-beta 67518 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115001&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2591914 252664462 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238897 N(N=Cc1ccccc1)C1=Nc2cccc3cccc1c23 InChI=1S/C18H13N3/c1-2-6-13(7-3-1)12-19-21-18-15-10-4-8-14-9-5-11-16(20-18)17(14)15/h1-12H,(H,20,21) BHVRGHUCIOBZDB-UHFFFAOYSA-N 51101 (benzalamino)-benzo[cd]indol-2-yl-amine::MLS000392783::N-(benzylideneamino)benzo[cd]indol-2-amine::N-[(phenylmethylene)amino]-2-benzo[cd]indolamine::N-[(phenylmethylidene)amino]benzo[cd]indol-2-amine::SMR000261715::[(E)-benzalamino]-benzo[cd]indol-2-yl-amine::cid_2315076 Oxysterols receptor LXR-beta 67540 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51101&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6899626 252631337 ZINC06440858 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238899 [O-][N+](=O)c1n[nH]c(C(=O)Nc2ccn(Cc3ccccc3)n2)c1Cl InChI=1S/C14H11ClN6O3/c15-11-12(17-18-13(11)21(23)24)14(22)16-10-6-7-20(19-10)8-9-4-2-1-3-5-9/h1-7H,8H2,(H,17,18)(H,16,19,22) JMTYOGKXLZBBGH-UHFFFAOYSA-N 72350 4-chloranyl-3-nitro-N-[1-(phenylmethyl)pyrazol-3-yl]-1H-pyrazole-5-carboxamide::4-chloro-3-nitro-N-[1-(phenylmethyl)-3-pyrazolyl]-1H-pyrazole-5-carboxamide::MLS000698607::N-(1-benzyl-1H-pyrazol-3-yl)-4-chloro-5-nitro-1H-pyrazole-3-carboxamide::N-(1-benzylpyrazol-3-yl)-4-chloro-3-nitro-1H-pyrazole-5-carboxamide::SMR000228119::cid_843505 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72350&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 843505 252649612 ZINC18162084 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238900 Cc1cccc(C=Cc2nc3ccccc3c(=O)[nH]2)c1 InChI=1S/C17H14N2O/c1-12-5-4-6-13(11-12)9-10-16-18-15-8-3-2-7-14(15)17(20)19-16/h2-11H,1H3,(H,18,19,20) BLVJYZMMPDHHHO-UHFFFAOYSA-N 49809 2-[(E)-2-(3-methylphenyl)ethenyl]-1H-quinazolin-4-one::2-[(E)-2-(m-tolyl)vinyl]-1H-quinazolin-4-one::2-[(Z)-2-(m-tolyl)vinyl]-1H-quinazolin-4-one::MLS000716115::SMR000277632::cid_5768144 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49809&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5768144 252630084 ZINC18045297 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238901 Cc1ccn(n1)-c1cccc(n1)-n1ccc(C)n1 InChI=1S/C13H13N5/c1-10-6-8-17(15-10)12-4-3-5-13(14-12)18-9-7-11(2)16-18/h3-9H,1-2H3 RAIXXDUNEZBGDR-UHFFFAOYSA-N 115003 2,6-bis(3-methyl-1-pyrazolyl)pyridine::2,6-bis(3-methyl-1H-pyrazol-1-yl)pyridine::2,6-bis(3-methylpyrazol-1-yl)pyridine::MLS000702817::SMR000229839::cid_850137 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115003&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 850137 252664463 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238902 Nc1ncc(Br)cc1\N=C\c1ccccc1 InChI=1S/C12H10BrN3/c13-10-6-11(12(14)16-8-10)15-7-9-4-2-1-3-5-9/h1-8H,(H2,14,16)/b15-7+ OZFHWELCBWFVEW-VIZOYTHASA-N 115004 3-(benzylideneamino)-5-bromopyridin-2-amine::5-bromanyl-3-[(phenylmethylidene)amino]pyridin-2-amine::5-bromo-3-[(phenylmethylene)amino]-2-pyridinamine::MLS000706620::N-(2-amino-5-bromo-3-pyridinyl)-N-benzylideneamine::SMR000229236::[3-(benzalamino)-5-bromo-2-pyridyl]amine::cid_838785 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115004&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 838785 252664464 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238903 CCC(=NNC(=O)c1ccoc1C)c1ccc(C)o1 InChI=1S/C14H16N2O3/c1-4-12(13-6-5-9(2)19-13)15-16-14(17)11-7-8-18-10(11)3/h5-8H,4H2,1-3H3,(H,16,17) YWMGQDPNMYSSLK-UHFFFAOYSA-N 115005 2-methyl-N'-[1-(5-methyl-2-furyl)propylidene]-3-furohydrazide::2-methyl-N-[(E)-1-(5-methyl-2-furanyl)propylideneamino]-3-furancarboxamide::2-methyl-N-[(E)-1-(5-methyl-2-furyl)propylideneamino]-3-furamide::2-methyl-N-[(E)-1-(5-methylfuran-2-yl)propylideneamino]furan-3-carboxamide::MLS000698059::SMR000227970::cid_5842394 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115005&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5842394 252664465 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238904 Cc1scc(C(=O)N\N=C\c2ccsc2)c1C InChI=1S/C12H12N2OS2/c1-8-9(2)17-7-11(8)12(15)14-13-5-10-3-4-16-6-10/h3-7H,1-2H3,(H,14,15)/b13-5+ SEFLPDGXFQMXCS-WLRTZDKTSA-N 115006 4,5-dimethyl-N'-(3-thienylmethylene)-3-thiophenecarbohydrazide::4,5-dimethyl-N-[(E)-3-thenylideneamino]thiophene-3-carboxamide::4,5-dimethyl-N-[(E)-3-thiophenylmethylideneamino]-3-thiophenecarboxamide::4,5-dimethyl-N-[(E)-thiophen-3-ylmethylideneamino]thiophene-3-carboxamide::MLS000699345::SMR000227975::cid_6875163 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115006&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6875163 252664466 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238905 Cc1ccc(Nc2ncccc2C(N)=O)cc1 InChI=1S/C13H13N3O/c1-9-4-6-10(7-5-9)16-13-11(12(14)17)3-2-8-15-13/h2-8H,1H3,(H2,14,17)(H,15,16) QSBJMVSZUKBBIL-UHFFFAOYSA-N 75495 2-(4-methylanilino)-3-pyridinecarboxamide::2-(4-methylanilino)pyridine-3-carboxamide::2-(4-toluidino)nicotinamide::2-(p-toluidino)nicotinamide::2-[(4-methylphenyl)amino]pyridine-3-carboxamide::MLS000700317::SMR000226873::cid_901941 Oxysterols receptor LXR-beta 67441 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75495&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 901941 252652702 ZINC00481313 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238906 Cc1ccc(Nc2ncccc2C(N)=O)cc1[N+]([O-])=O InChI=1S/C13H12N4O3/c1-8-4-5-9(7-11(8)17(19)20)16-13-10(12(14)18)3-2-6-15-13/h2-7H,1H3,(H2,14,18)(H,15,16) OSBQBRNMQSMSFD-UHFFFAOYSA-N 115007 2-(4-methyl-3-nitro-anilino)nicotinamide::2-(4-methyl-3-nitroanilino)-3-pyridinecarboxamide::2-(4-methyl-3-nitroanilino)pyridine-3-carboxamide::2-[(4-methyl-3-nitro-phenyl)amino]pyridine-3-carboxamide::2-{3-nitro-4-methylanilino}nicotinamide::MLS000700314::SMR000226870::cid_901926 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115007&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 901926 252664467 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238907 O=C(\C=C\c1ccccc1)N1CCC(C1)c1ccccc1 InChI=1S/C19H19NO/c21-19(12-11-16-7-3-1-4-8-16)20-14-13-18(15-20)17-9-5-2-6-10-17/h1-12,18H,13-15H2/b12-11+ FKRPYXCRUAIJQQ-VAWYXSNFSA-N 115008 (E)-3-phenyl-1-(3-phenyl-1-pyrrolidinyl)-2-propen-1-one::(E)-3-phenyl-1-(3-phenylpyrrolidin-1-yl)prop-2-en-1-one::(E)-3-phenyl-1-(3-phenylpyrrolidino)prop-2-en-1-one::1-cinnamoyl-3-phenylpyrrolidine::MLS000666535::SMR000268864::cid_5729968 Oxysterols receptor LXR-beta 67522 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115008&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5729968 252664468 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238908 Fc1ccc(cc1)-n1nnc(n1)-c1cccnc1Cl InChI=1S/C12H7ClFN5/c13-11-10(2-1-7-15-11)12-16-18-19(17-12)9-5-3-8(14)4-6-9/h1-7H FJEQSNOGJXPASP-UHFFFAOYSA-N 49719 2-chloranyl-3-[2-(4-fluorophenyl)-1,2,3,4-tetrazol-5-yl]pyridine::2-chloro-3-(2-(4-fluorophenyl)-2H-tetrazol-5-yl)pyridine::2-chloro-3-[2-(4-fluorophenyl)-5-tetrazolyl]pyridine::2-chloro-3-[2-(4-fluorophenyl)tetrazol-5-yl]pyridine::MLS000697778::SMR000327356::cid_16066526 Oxysterols receptor LXR-beta 67479 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49719&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16066526 252629994 ZINC13545559 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238909 Cc1cc(ccc1NS(=O)(=O)c1cccs1)-c1nc2cccnc2s1 InChI=1S/C17H13N3O2S3/c1-11-10-12(16-19-14-4-2-8-18-17(14)24-16)6-7-13(11)20-25(21,22)15-5-3-9-23-15/h2-10,20H,1H3 WZNVRQOYBMQWKT-UHFFFAOYSA-N 115009 MLS000529674::N-(2-methyl-4-thiazolo[5,4-b]pyridin-2-yl-phenyl)thiophene-2-sulfonamide::N-[2-methyl-4-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2-thiophenesulfonamide::N-[2-methyl-4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]thiophene-2-sulfonamide::SMR000127210::cid_16187060 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115009&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16187060 252664469 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238910 CCn1c(O)c(C=Nc2ccccc2)sc1=S InChI=1S/C12H12N2OS2/c1-2-14-11(15)10(17-12(14)16)8-13-9-6-4-3-5-7-9/h3-8,15H,2H2,1H3 ZMUTZNCDEDSUFW-UHFFFAOYSA-N 74916 (5Z)-3-ethyl-5-(phenylazanylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one::(5Z)-5-(anilinomethylene)-3-ethyl-2-thioxo-thiazolidin-4-one::(5Z)-5-(anilinomethylidene)-3-ethyl-2-sulfanylidene-1,3-thiazolidin-4-one::(5Z)-5-(anilinomethylidene)-3-ethyl-2-sulfanylidene-4-thiazolidinone::MLS000710415::SMR000280182::cid_5373057 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=74916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=74916&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5373057 252652134 ZINC12625460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238911 CC(N(C)C(=O)CCc1nnc(CCC2CCCCC2)o1)c1cccs1 InChI=1S/C20H29N3O2S/c1-15(17-9-6-14-26-17)23(2)20(24)13-12-19-22-21-18(25-19)11-10-16-7-4-3-5-8-16/h6,9,14-16H,3-5,7-8,10-13H2,1-2H3 RQEUFHOJAPAUCA-UHFFFAOYSA-N 115010 3-[5-(2-cyclohexylethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-(1-thiophen-2-ylethyl)propanamide::3-[5-(2-cyclohexylethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-[1-(2-thienyl)ethyl]propanamide::3-[5-(2-cyclohexylethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-[1-(2-thienyl)ethyl]propionamide::MLS000731697::SMR000318996::cid_16188383 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16188383 252664470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238912 COCC1CCN(Cc2nc(no2)-c2cccs2)C1 InChI=1S/C13H17N3O2S/c1-17-9-10-4-5-16(7-10)8-12-14-13(15-18-12)11-3-2-6-19-11/h2-3,6,10H,4-5,7-9H2,1H3 WVYAQXZPLIQQEL-UHFFFAOYSA-N 115011 5-[[3-(methoxymethyl)-1-pyrrolidinyl]methyl]-3-thiophen-2-yl-1,2,4-oxadiazole::5-[[3-(methoxymethyl)pyrrolidin-1-yl]methyl]-3-thiophen-2-yl-1,2,4-oxadiazole::5-[[3-(methoxymethyl)pyrrolidino]methyl]-3-(2-thienyl)-1,2,4-oxadiazole::5-{[3-(methoxymethyl)pyrrolidin-1-yl]methyl}-3-(2-thienyl)-1,2,4-oxadiazole::MLS000733629::SMR000317964::cid_16188699 Oxysterols receptor LXR-beta 67513 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16188699 252664471 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238913 O=C(NCCCn1ccnc1)c1cc(on1)-c1ccccc1 InChI=1S/C16H16N4O2/c21-16(18-7-4-9-20-10-8-17-12-20)14-11-15(22-19-14)13-5-2-1-3-6-13/h1-3,5-6,8,10-12H,4,7,9H2,(H,18,21) FLWZIODGHJAZJD-UHFFFAOYSA-N 49766 MLS000708948::N-(3-imidazol-1-ylpropyl)-5-phenyl-1,2-oxazole-3-carboxamide::N-(3-imidazol-1-ylpropyl)-5-phenyl-isoxazole-3-carboxamide::N-[3-(1-imidazolyl)propyl]-5-phenyl-3-isoxazolecarboxamide::SMR000289715::cid_2962284 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49766&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2962284 252630041 ZINC06110608 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238914 Cc1ccc2oc(nc2c1)-c1cccc(N)c1 InChI=1S/C14H12N2O/c1-9-5-6-13-12(7-9)16-14(17-13)10-3-2-4-11(15)8-10/h2-8H,15H2,1H3 YGMVUJGLTNKWJJ-UHFFFAOYSA-N 49767 3-(5-methyl-1,3-benzoxazol-2-yl)aniline::MLS000710395::SMR000280162::[3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]amine::cid_348698 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49767&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 348698 252630042 ZINC00122953 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238915 COCCNC(=O)C(=C\c1cc(C)n(c1C)-c1ccc(C)cc1)\C#N InChI=1S/C20H23N3O2/c1-14-5-7-19(8-6-14)23-15(2)11-17(16(23)3)12-18(13-21)20(24)22-9-10-25-4/h5-8,11-12H,9-10H2,1-4H3,(H,22,24)/b18-12+ JHMGNUKCJAFHQI-LDADJPATSA-N 49768 (E)-2-cyano-3-[2,5-dimethyl-1-(4-methylphenyl)-3-pyrrolyl]-N-(2-methoxyethyl)-2-propenamide::(E)-2-cyano-3-[2,5-dimethyl-1-(4-methylphenyl)pyrrol-3-yl]-N-(2-methoxyethyl)prop-2-enamide::(E)-2-cyano-3-[2,5-dimethyl-1-(p-tolyl)pyrrol-3-yl]-N-(2-methoxyethyl)acrylamide::MLS000711883::SMR000281650::cid_5766269 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49768&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5766269 252630043 ZINC04994046 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238916 Clc1ccc(OCCSc2ncccn2)c(Br)c1 InChI=1S/C12H10BrClN2OS/c13-10-8-9(14)2-3-11(10)17-6-7-18-12-15-4-1-5-16-12/h1-5,8H,6-7H2 MSVBXLUEPIYGMR-UHFFFAOYSA-N 93816 2-[2-(2-bromanyl-4-chloranyl-phenoxy)ethylsulfanyl]pyrimidine::2-[2-(2-bromo-4-chloro-phenoxy)ethylthio]pyrimidine::2-[2-(2-bromo-4-chlorophenoxy)ethylsulfanyl]pyrimidine::2-[2-(2-bromo-4-chlorophenoxy)ethylthio]pyrimidine::2-{[2-(2-bromo-4-chlorophenoxy)ethyl]thio}pyrimidine::MLS000675409::SMR000293424::cid_2199876 Oxysterols receptor LXR-beta 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93816&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2199876 164035060 ZINC02845271 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238917 COc1cccc(c1)-c1nc(no1)-c1ccc(Br)o1 InChI=1S/C13H9BrN2O3/c1-17-9-4-2-3-8(7-9)13-15-12(16-19-13)10-5-6-11(14)18-10/h2-7H,1H3 UXGUULAJPLEVKH-UHFFFAOYSA-N 115012 3-(5-bromanylfuran-2-yl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furanyl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-(3-methoxyphenyl)-1,2,4-oxadiazole::MLS000674412::SMR000297369::cid_717858 Oxysterols receptor LXR-beta 67493 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 717858 252664472 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238918 Brc1ccc(o1)-c1noc(n1)-c1ccccc1 InChI=1S/C12H7BrN2O2/c13-10-7-6-9(16-10)11-14-12(17-15-11)8-4-2-1-3-5-8/h1-7H MFTLYVBFNAAAHY-UHFFFAOYSA-N 115013 3-(5-bromanylfuran-2-yl)-5-phenyl-1,2,4-oxadiazole::3-(5-bromo-2-furanyl)-5-phenyl-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-phenyl-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-phenyl-1,2,4-oxadiazole::MLS000674457::SMR000297412::cid_5150753 Oxysterols receptor LXR-beta 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5150753 252664473 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238919 NC(=NOC(=O)c1cc(Br)ccc1Cl)c1ccccn1 InChI=1S/C13H9BrClN3O2/c14-8-4-5-10(15)9(7-8)13(19)20-18-12(16)11-3-1-2-6-17-11/h1-7H,(H2,16,18) CGXGAXMMGDPJML-UHFFFAOYSA-N 49794 5-bromo-2-chloro-benzoic acid [(Z)-[amino(2-pyridyl)methylene]amino] ester::5-bromo-2-chlorobenzoic acid [(Z)-[amino(2-pyridinyl)methylidene]amino] ester::MLS000625126::N'-[(5-bromo-2-chlorobenzoyl)oxy]-2-pyridinecarboximidamide::SMR000293913::[(Z)-[amino(pyridin-2-yl)methylidene]amino] 5-bromo-2-chlorobenzoate::[(Z)-[azanyl(pyridin-2-yl)methylidene]amino] 5-bromanyl-2-chloranyl-benzoate::cid_9587775 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49794&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9587775 252630069 ZINC05059847 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238920 Cc1ccc(cc1)-c1csc(NC(=O)\C=C\c2ccco2)c1C(O)=O InChI=1S/C19H15NO4S/c1-12-4-6-13(7-5-12)15-11-25-18(17(15)19(22)23)20-16(21)9-8-14-3-2-10-24-14/h2-11H,1H3,(H,20,21)(H,22,23)/b9-8+ VMPSOGVIMUYKTH-CMDGGOBGSA-N 115014 2-[[(E)-3-(2-furanyl)-1-oxoprop-2-enyl]amino]-4-(4-methylphenyl)-3-thiophenecarboxylic acid::2-[[(E)-3-(2-furyl)acryloyl]amino]-4-(p-tolyl)-3-thenoic acid::2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]-4-(4-methylphenyl)thiophene-3-carboxylic acid::2-{[3-(2-furyl)acryloyl]amino}-4-(4-methylphenyl)-3-thiophenecarboxylic acid::MLS000673879::SMR000297919::cid_1206157 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1206157 252664474 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238921 CC(C)CN1CCN(Cc2ccc(C)s2)CC1CCO InChI=1S/C16H28N2OS/c1-13(2)10-18-8-7-17(11-15(18)6-9-19)12-16-5-4-14(3)20-16/h4-5,13,15,19H,6-12H2,1-3H3 ZEMAHOYXOAHHGN-UHFFFAOYSA-N 72483 2-[1-(2-methylpropyl)-4-[(5-methyl-2-thiophenyl)methyl]-2-piperazinyl]ethanol::2-[1-(2-methylpropyl)-4-[(5-methylthiophen-2-yl)methyl]piperazin-2-yl]ethanol::2-[1-isobutyl-4-[(5-methyl-2-thienyl)methyl]piperazin-2-yl]ethanol::2-{1-isobutyl-4-[(5-methyl-2-thienyl)methyl]piperazin-2-yl}ethanol::MLS000734180::SMR000317233::cid_16191481 Oxysterols receptor LXR-beta 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72483&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16191481 252649743 ZINC36385751 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238922 CN1C(=O)\C(=N/NC(=O)c2ccco2)c2ccccc12 InChI=1S/C14H11N3O3/c1-17-10-6-3-2-5-9(10)12(14(17)19)15-16-13(18)11-7-4-8-20-11/h2-8H,1H3,(H,16,18)/b15-12- OABKHWMTAHJLEU-QINSGFPZSA-N 115015 MLS000716276::N-[(Z)-(1-methyl-2-oxidanylidene-indol-3-ylidene)amino]furan-2-carboxamide::N-[(Z)-(1-methyl-2-oxo-3-indolylidene)amino]-2-furancarboxamide::N-[(Z)-(1-methyl-2-oxoindol-3-ylidene)amino]furan-2-carboxamide::N-[(Z)-(2-keto-1-methyl-indolin-3-ylidene)amino]-2-furamide::SMR000277793::cid_5720547 Oxysterols receptor LXR-beta 67471 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5720547 252664475 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238923 O=C(Nc1ccccn1)c1csc2CCCCc12 InChI=1S/C14H14N2OS/c17-14(16-13-7-3-4-8-15-13)11-9-18-12-6-2-1-5-10(11)12/h3-4,7-9H,1-2,5-6H2,(H,15,16,17) UCQAMKMTOLXIEF-UHFFFAOYSA-N 115016 MLS000711438::N-(2-pyridinyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide::N-(2-pyridyl)-4,5,6,7-tetrahydrobenzothiophene-3-carboxamide::N-pyridin-2-yl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide::SMR000281205::cid_829296 Oxysterols receptor LXR-beta 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115016&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 829296 252664476 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238924 COC1=C\C(=C\c2c(N)n3nc(sc3nc2=O)-c2ccc(C)cc2)C=CC1=O InChI=1S/C20H16N4O3S/c1-11-3-6-13(7-4-11)19-23-24-17(21)14(18(26)22-20(24)28-19)9-12-5-8-15(25)16(10-12)27-2/h3-10H,21H2,1-2H3/b12-9+ GBAMFVYOEZXVMB-FMIVXFBMSA-N 50476 5-amino-6-[(E)-(3-methoxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-2-(4-methylphenyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::5-amino-6-[(E)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-(4-methylphenyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::5-amino-6-[(E)-(4-keto-3-methoxy-cyclohexa-2,5-dien-1-ylidene)methyl]-2-(p-tolyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::5-azanyl-6-[(E)-(3-methoxy-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]-2-(4-methylphenyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::6-(4-hydroxy-3-methoxybenzylidene)-5-imino-2-(4-methylphenyl)-5,6-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::MLS000676609::SMR000298487::cid_5874617 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5874617 252630736 ZINC61865713 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238925 OC(=O)c1cc(n[nH]1)-c1cccs1 InChI=1S/C8H6N2O2S/c11-8(12)6-4-5(9-10-6)7-2-1-3-13-7/h1-4H,(H,9,10)(H,11,12) DUDBNCNNJMOLCC-UHFFFAOYSA-N 115017 5-(2-thienyl)-1H-pyrazole-3-carboxylic acid::5-thiophen-2-yl-1H-pyrazole-3-carboxylic acid::MLS000716528::SMR000278045::cid_818268 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115017&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 818268 252664477 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238926 COC(=O)c1sc2nc3CCCCc3cc2c1N InChI=1S/C13H14N2O2S/c1-17-13(16)11-10(14)8-6-7-4-2-3-5-9(7)15-12(8)18-11/h6H,2-5,14H2,1H3 GVZNNNWVSDWYFO-UHFFFAOYSA-N 49828 3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid methyl ester::MLS000708481::SMR000287948::cid_2838748::methyl 3-amino-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate::methyl 3-azanyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylate Oxysterols receptor LXR-beta 67510 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49828&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2838748 252630103 ZINC02495877 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238927 CCCSc1nsc(NC(=O)CC)n1 InChI=1S/C8H13N3OS2/c1-3-5-13-8-10-7(14-11-8)9-6(12)4-2/h3-5H2,1-2H3,(H,9,10,11,12) XHBGDQMFERCBGL-UHFFFAOYSA-N 115018 MLS000717160::N-(3-propylsulfanyl-1,2,4-thiadiazol-5-yl)propanamide::N-[3-(propylthio)-1,2,4-thiadiazol-5-yl]propanamide::N-[3-(propylthio)-1,2,4-thiadiazol-5-yl]propionamide::SMR000278527::cid_3128534 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3128534 252664478 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238928 Cc1ccc(cc1)-c1cn2cccnc2n1 InChI=1S/C13H11N3/c1-10-3-5-11(6-4-10)12-9-16-8-2-7-14-13(16)15-12/h2-9H,1H3 FXPRTYODRQWLLM-UHFFFAOYSA-N 115019 2-(4-methylphenyl)imidazo[1,2-a]pyrimidine::2-(p-tolyl)imidazo[1,2-a]pyrimidine::MLS000707292::SMR000288757::cid_727295 Oxysterols receptor LXR-beta 67635 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115019&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 727295 252664479 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238929 O=C(Nc1ccccn1)C(=O)Nc1ccccn1 InChI=1S/C12H10N4O2/c17-11(15-9-5-1-3-7-13-9)12(18)16-10-6-2-4-8-14-10/h1-8H,(H,13,15,17)(H,14,16,18) AEGDXMYEDPEYCG-UHFFFAOYSA-N 69226 MLS000766036::N,N'-bis(2-pyridinyl)oxamide::N,N'-bis(2-pyridyl)oxamide::N,N'-dipyridin-2-ylethanediamide::N,N'-dipyridin-2-yloxamide::SMR000279742::cid_1927420 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69226&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1927420 252647394 ZINC15909496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238930 COCCNC(=O)C(=C\c1cc(C)n(C2CCCCC2)c1C)\C#N InChI=1S/C19H27N3O2/c1-14-11-16(12-17(13-20)19(23)21-9-10-24-3)15(2)22(14)18-7-5-4-6-8-18/h11-12,18H,4-10H2,1-3H3,(H,21,23)/b17-12+ WHVBXRMNFAHENC-SFQUDFHCSA-N 115020 (E)-2-cyano-3-(1-cyclohexyl-2,5-dimethyl-3-pyrrolyl)-N-(2-methoxyethyl)-2-propenamide::(E)-2-cyano-3-(1-cyclohexyl-2,5-dimethyl-pyrrol-3-yl)-N-(2-methoxyethyl)acrylamide::(E)-2-cyano-3-(1-cyclohexyl-2,5-dimethyl-pyrrol-3-yl)-N-(2-methoxyethyl)prop-2-enamide::(E)-2-cyano-3-(1-cyclohexyl-2,5-dimethylpyrrol-3-yl)-N-(2-methoxyethyl)prop-2-enamide::MLS000710555::SMR000280322::cid_5766786 Oxysterols receptor LXR-beta 67509 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115020&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5766786 252664480 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238931 CN1CCS\C1=C/C=C1\N(C)C(=S)N(C)C1=O InChI=1S/C11H15N3OS2/c1-12-6-7-17-9(12)5-4-8-10(15)14(3)11(16)13(8)2/h4-5H,6-7H2,1-3H3/b8-4-,9-5- FVFBOOXTOBVBGN-XEQVNJCQSA-N 115021 (5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-2-sulfanylidene-imidazolidin-4-one::(5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methyl-1,3-thiazolidin-2-ylidene)ethylidene]-2-sulfanylideneimidazolidin-4-one::(5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methyl-2-thiazolidinylidene)ethylidene]-2-sulfanylidene-4-imidazolidinone::(5Z)-1,3-dimethyl-5-[(2Z)-2-(3-methylthiazolidin-2-ylidene)ethylidene]-2-thioxo-4-imidazolidinone::1,3-Dimethyl-5-[2-(3-methyl-thiazolidin-2-ylidene)-ethylidene]-2-thioxo-imidazol::MLS000724094::SMR000305689::cid_5568081 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115021&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5568081 252664481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238932 Cc1ccc(NN=C(C#N)C(=N)N2CCCCCC2)cc1 InChI=1S/C16H21N5/c1-13-6-8-14(9-7-13)19-20-15(12-17)16(18)21-10-4-2-3-5-11-21/h6-9,18-19H,2-5,10-11H2,1H3 QYMPACHMHMQLTD-UHFFFAOYSA-N 49867 (2E)-3-(azepan-1-yl)-3-imino-2-(p-tolylhydrazono)propionitrile::(2E)-3-azepan-1-yl-3-imino-2-[(4-methylphenyl)hydrazono]propanenitrile::2-(azepan-1-yl)-2-imino-N-(4-methylanilino)ethanimidoyl cyanide::3-(1-azepanyl)-3-imino-2-[(4-methylphenyl)hydrazinylidene]propanenitrile::3-(azepan-1-yl)-3-imino-2-(p-tolylhydrazono)propionitrile::3-azanylidene-3-(azepan-1-yl)-2-[(4-methylphenyl)hydrazinylidene]propanenitrile::MLS000728136::SMR000306829::cid_6805932 Oxysterols receptor LXR-beta 67466 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49867&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6401033 252630142 ZINC02904280 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238933 C(Sc1ccc(nn1)-c1ccccn1)c1ccccn1 InChI=1S/C15H12N4S/c1-3-9-16-12(5-1)11-20-15-8-7-14(18-19-15)13-6-2-4-10-17-13/h1-10H,11H2 BMHGUWQJWGVXMD-UHFFFAOYSA-N 115023 3-(2-pyridinyl)-6-(2-pyridinylmethylthio)pyridazine::3-(2-pyridyl)-6-(2-pyridylmethylthio)pyridazine::3-pyridin-2-yl-6-(pyridin-2-ylmethylsulfanyl)pyridazine::MLS000678515::SMR000323987::cid_7162438 Oxysterols receptor LXR-beta 67475 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115023&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7162438 252664482 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238934 COc1ccc(Oc2cnn(-c3ccccc3)c(=O)c2Br)cc1 InChI=1S/C17H13BrN2O3/c1-22-13-7-9-14(10-8-13)23-15-11-19-20(17(21)16(15)18)12-5-3-2-4-6-12/h2-11H,1H3 QWURXOMVQVPBSF-UHFFFAOYSA-N 115024 4-bromanyl-5-(4-methoxyphenoxy)-2-phenyl-pyridazin-3-one::4-bromo-5-(4-methoxyphenoxy)-2-phenyl-3(2H)-pyridazinone::4-bromo-5-(4-methoxyphenoxy)-2-phenyl-3-pyridazinone::4-bromo-5-(4-methoxyphenoxy)-2-phenyl-pyridazin-3-one::4-bromo-5-(4-methoxyphenoxy)-2-phenylpyridazin-3-one::MLS000720559::SMR000336319::cid_1480667 Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115024&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1480667 252664483 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238935 Nc1nn(cc1-c1ccccc1)-c1cccc(F)n1 InChI=1S/C14H11FN4/c15-12-7-4-8-13(17-12)19-9-11(14(16)18-19)10-5-2-1-3-6-10/h1-9H,(H2,16,18) XHTYRUFTVZVORB-UHFFFAOYSA-N 49904 1-(6-fluoranylpyridin-2-yl)-4-phenyl-pyrazol-3-amine::1-(6-fluoro-2-pyridinyl)-4-phenyl-1H-pyrazol-3-amine::1-(6-fluoro-2-pyridinyl)-4-phenyl-3-pyrazolamine::1-(6-fluoropyridin-2-yl)-4-phenylpyrazol-3-amine::MLS000694607::SMR000333273::[1-(6-fluoro-2-pyridyl)-4-phenyl-pyrazol-3-yl]amine::cid_1478415 Oxysterols receptor LXR-beta 67459 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49904&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1478415 252630178 ZINC01391064 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238936 CN(C)C(C)=CC(=O)c1sccc1Cl InChI=1S/C10H12ClNOS/c1-7(12(2)3)6-9(13)10-8(11)4-5-14-10/h4-6H,1-3H3 OTCHHTIPXGJWQX-UHFFFAOYSA-N 115025 (E)-1-(3-chloranylthiophen-2-yl)-3-(dimethylamino)but-2-en-1-one::(E)-1-(3-chloro-2-thienyl)-3-(dimethylamino)-2-buten-1-one::(E)-1-(3-chloro-2-thienyl)-3-(dimethylamino)but-2-en-1-one::(E)-1-(3-chloro-2-thiophenyl)-3-(dimethylamino)-2-buten-1-one::(E)-1-(3-chlorothiophen-2-yl)-3-(dimethylamino)but-2-en-1-one::MLS000720628::SMR000336368::cid_5525417 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115025&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5525417 252664484 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238937 CN(C)C=NC(=S)Nc1ccc(Cl)cc1 InChI=1S/C10H12ClN3S/c1-14(2)7-12-10(15)13-9-5-3-8(11)4-6-9/h3-7H,1-2H3,(H,13,15) RHZZAPBYVAKUFY-UHFFFAOYSA-N 115026 (3E)-1-(4-chlorophenyl)-3-(dimethylaminomethylene)thiourea::(3E)-1-(4-chlorophenyl)-3-(dimethylaminomethylidene)thiourea::MLS000694855::N-(4-chlorophenyl)-N'-[(dimethylamino)methylene]thiourea::SMR000333173::cid_9581725 Oxysterols receptor LXR-beta 67490 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115026&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9581725 252664485 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238938 C(N=C1Nc2ccccc2CS1)c1ccccn1 InChI=1S/C14H13N3S/c1-2-7-13-11(5-1)10-18-14(17-13)16-9-12-6-3-4-8-15-12/h1-8H,9-10H2,(H,16,17) XNMRPWZYTMZSDO-UHFFFAOYSA-N 115027 4H-3,1-benzothiazin-2-yl(2-pyridylmethyl)amine::MLS000696218::N-(2-pyridinylmethyl)-4H-3,1-benzothiazin-2-amine::N-(pyridin-2-ylmethyl)-4H-3,1-benzothiazin-2-amine::SMR000333326::cid_3838280 Oxysterols receptor LXR-beta 67539 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115027&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3838280 252664486 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238939 CN(C)c1ccc(nn1)C(C#N)c1ccccc1 InChI=1S/C14H14N4/c1-18(2)14-9-8-13(16-17-14)12(10-15)11-6-4-3-5-7-11/h3-9,12H,1-2H3 GWTNXVVXWAWFKQ-UHFFFAOYSA-N 115028 2-[6-(dimethylamino)-3-pyridazinyl]-2-phenylacetonitrile::2-[6-(dimethylamino)pyridazin-3-yl]-2-phenyl-acetonitrile::2-[6-(dimethylamino)pyridazin-3-yl]-2-phenyl-ethanenitrile::2-[6-(dimethylamino)pyridazin-3-yl]-2-phenylacetonitrile::MLS000763691::SMR000334028::cid_6409760 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115028&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6409760 252664487 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238940 C\C(=N\OCc1ccc(Br)cc1)c1ccccn1 InChI=1S/C14H13BrN2O/c1-11(14-4-2-3-9-16-14)17-18-10-12-5-7-13(15)8-6-12/h2-9H,10H2,1H3/b17-11- PBNSAAZNKRYIIS-BOPFTXTBSA-N 93843 (Z)-(4-bromobenzyl)oxy-[1-(2-pyridyl)ethylidene]amine::(Z)-N-[(4-bromophenyl)methoxy]-1-(2-pyridinyl)ethanimine::(Z)-N-[(4-bromophenyl)methoxy]-1-pyridin-2-yl-ethanimine::(Z)-N-[(4-bromophenyl)methoxy]-1-pyridin-2-ylethanimine::1-(2-pyridinyl)-1-ethanone O-(4-bromobenzyl)oxime::MLS000755711::SMR000337380::cid_5903888 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93843&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5903888 164035087 ZINC04106574 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238941 Clc1ccc(NN=C(C#N)C(=N)N2CCCCCC2)cc1 InChI=1S/C15H18ClN5/c16-12-5-7-13(8-6-12)19-20-14(11-17)15(18)21-9-3-1-2-4-10-21/h5-8,18-19H,1-4,9-10H2 HIZSAVZDDKUQKB-UHFFFAOYSA-N 115029 (1E)-2-(azepan-1-yl)-N-(4-chloroanilino)-2-iminoethanimidoyl cyanide::(2E)-3-(1-azepanyl)-2-[(4-chlorophenyl)hydrazinylidene]-3-iminopropanenitrile::(2E)-3-(azepan-1-yl)-2-[(4-chlorophenyl)hydrazono]-3-imino-propionitrile::(2E)-3-azanylidene-3-(azepan-1-yl)-2-[(4-chlorophenyl)hydrazinylidene]propanenitrile::(2E)-3-azepan-1-yl-2-[(4-chlorophenyl)hydrazono]-3-iminopropanenitrile::MLS000728147::SMR000306840::cid_6401039 Oxysterols receptor LXR-beta 67493 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115029&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6401039 252664488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238942 Oc1ccccc1NC(=O)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1 InChI=1S/C22H17N3O4S/c26-19-8-2-1-7-18(19)24-22(27)16-10-12-17(13-11-16)25-30(28,29)20-9-3-5-15-6-4-14-23-21(15)20/h1-14,25-26H,(H,24,27) VFPIDGYYGNFYMH-UHFFFAOYSA-N 49938 MLS000686747::N-(2-hydroxyphenyl)-4-(8-quinolinylsulfonylamino)benzamide::N-(2-hydroxyphenyl)-4-(8-quinolylsulfonylamino)benzamide::N-(2-hydroxyphenyl)-4-(quinolin-8-ylsulfonylamino)benzamide::N-(2-hydroxyphenyl)-4-[(quinolin-8-ylsulfonyl)amino]benzamide::SMR000339837::cid_5045370 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49938&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5045370 252630212 ZINC03635605 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238943 CCOC(=O)c1c(C)[nH]c(N=Nc2cccc(OC)c2)c1C InChI=1S/C16H19N3O3/c1-5-22-16(20)14-10(2)15(17-11(14)3)19-18-12-7-6-8-13(9-12)21-4/h6-9,17H,5H2,1-4H3/b19-18+ PIPALFJORLHUMM-VHEBQXMUSA-N 76554 (5Z)-5-[(3-methoxyphenyl)hydrazinylidene]-2,4-dimethyl-3-pyrrolecarboxylic acid ethyl ester::(5Z)-5-[(3-methoxyphenyl)hydrazono]-2,4-dimethyl-pyrrole-3-carboxylic acid ethyl ester::MLS001007421::SMR000352587::cid_5340317::ethyl (5Z)-5-[(3-methoxyphenyl)hydrazinylidene]-2,4-dimethyl-pyrrole-3-carboxylate::ethyl (5Z)-5-[(3-methoxyphenyl)hydrazinylidene]-2,4-dimethylpyrrole-3-carboxylate Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76554&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5340317 252653732 ZINC12625489 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238944 Cc1cc(C(=O)CSc2cccc[n+]2[O-])c(C)n1-c1ccccc1 InChI=1S/C19H18N2O2S/c1-14-12-17(15(2)21(14)16-8-4-3-5-9-16)18(22)13-24-19-10-6-7-11-20(19)23/h3-12H,13H2,1-2H3 NZCDKYVOTDASIH-UHFFFAOYSA-N 115030 1-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-2-[(1-oxido-2-pyridin-1-iumyl)thio]ethanone::1-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-2-(1-oxidanidylpyridin-1-ium-2-yl)sulfanyl-ethanone::1-(2,5-dimethyl-1-phenyl-pyrrol-3-yl)-2-[(1-oxidopyridin-1-ium-2-yl)thio]ethanone::1-(2,5-dimethyl-1-phenylpyrrol-3-yl)-2-(1-oxidopyridin-1-ium-2-yl)sulfanylethanone::MLS000770655::SMR000343845::cid_2453287 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2453287 252664489 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238945 Cc1ccc(OCc2ccc(Br)cc2)c(n1)[N+]([O-])=O InChI=1S/C13H11BrN2O3/c1-9-2-7-12(13(15-9)16(17)18)19-8-10-3-5-11(14)6-4-10/h2-7H,8H2,1H3 IFDGERBZNBLBRL-UHFFFAOYSA-N 115031 3-(4-bromobenzyl)oxy-6-methyl-2-nitro-pyridine::3-[(4-bromophenyl)methoxy]-6-methyl-2-nitro-pyridine::3-[(4-bromophenyl)methoxy]-6-methyl-2-nitropyridine::MLS000517075::SMR000343244::cid_3462706 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115031&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3462706 252664490 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238946 CC(=NNC(=O)OC(C)(C)C)c1ccc[nH]1 InChI=1S/C11H17N3O2/c1-8(9-6-5-7-12-9)13-14-10(15)16-11(2,3)4/h5-7,12H,1-4H3,(H,14,15) HDLSCKWETHIZPN-UHFFFAOYSA-N 115032 MLS001017988::N-[[(1Z)-1-(2-pyrrolylidene)ethyl]amino]carbamic acid tert-butyl ester::N-[[(1Z)-1-pyrrol-2-ylideneethyl]amino]carbamic acid tert-butyl ester::SMR000354192::cid_16196079::tert-butyl N-[[(1Z)-1-pyrrol-2-ylideneethyl]amino]carbamate Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16196079 252664491 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238947 COc1ccc(\C=C2/SC(=O)N(CCNC(=O)C3CC4CC3C=C4)C2=O)cc1 InChI=1S/C21H22N2O4S/c1-27-16-6-3-13(4-7-16)12-18-20(25)23(21(26)28-18)9-8-22-19(24)17-11-14-2-5-15(17)10-14/h2-7,12,14-15,17H,8-11H2,1H3,(H,22,24)/b18-12- WLDNKAUYZYEEKC-PDGQHHTCSA-N 49951 MLS001010697::N-[2-[(5Z)-2,4-diketo-5-p-anisylidene-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide::N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-bis(oxidanylidene)-1,3-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide::N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide::N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-3-thiazolidinyl]ethyl]-5-bicyclo[2.2.1]hept-2-enecarboxamide::SMR000352864::cid_5969645 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49951&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5969645 252630225 ZINC07238902 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238948 CN=c1scc(-c2cccs2)n1N=C(C)c1ccco1 InChI=1S/C14H13N3OS2/c1-10(12-5-3-7-18-12)16-17-11(9-20-14(17)15-2)13-6-4-8-19-13/h3-9H,1-2H3 SYZLBZVIQPEBQM-UHFFFAOYSA-N 115033 (E)-1-(2-furyl)ethylidene-[2-methylimino-4-(2-thienyl)-4-thiazolin-3-yl]amine::(E)-3-[(E)-1-(2-furanyl)ethylideneamino]-N-methyl-4-thiophen-2-yl-2-thiazolimine::(E)-3-[(E)-1-(furan-2-yl)ethylideneamino]-N-methyl-4-thiophen-2-yl-1,3-thiazol-2-imine::MLS001033069::SMR000385489::cid_9630484 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115033&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9630484 252664492 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238949 CCOc1cc(\C=C(/C#N)c2nc3ccccc3[nH]2)ccc1OC(C)C(O)=O InChI=1S/C21H19N3O4/c1-3-27-19-11-14(8-9-18(19)28-13(2)21(25)26)10-15(12-22)20-23-16-6-4-5-7-17(16)24-20/h4-11,13H,3H2,1-2H3,(H,23,24)(H,25,26)/b15-10+ XAVGNURUZYXXSR-XNTDXEJSSA-N 53120 2-[4-[(E)-2-(1H-benzimidazol-2-yl)-2-cyano-ethenyl]-2-ethoxy-phenoxy]propanoic acid::2-[4-[(E)-2-(1H-benzimidazol-2-yl)-2-cyano-vinyl]-2-ethoxy-phenoxy]propionic acid::2-[4-[(E)-2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2-ethoxyphenoxy]propanoic acid::2-{4-[2-(1H-Benzoimidazol-2-yl)-2-cyano-vinyl]-2-ethoxy-phenoxy}-propionic acid::MLS001207004::SMR000523914::cid_5733133 Oxysterols receptor LXR-beta 67487 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53120&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5733133 252633253 ZINC03287133 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238950 Cc1cc(C(=O)CSc2ncccn2)c(C)n1Cc1ccco1 InChI=1S/C17H17N3O2S/c1-12-9-15(13(2)20(12)10-14-5-3-8-22-14)16(21)11-23-17-18-6-4-7-19-17/h3-9H,10-11H2,1-2H3 LEXHQYYEOGWFKR-UHFFFAOYSA-N 115034 1-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]-2-(2-pyrimidinylthio)ethanone::1-[1-(2-furfuryl)-2,5-dimethyl-pyrrol-3-yl]-2-(2-pyrimidylthio)ethanone::1-[1-(furan-2-ylmethyl)-2,5-dimethyl-pyrrol-3-yl]-2-pyrimidin-2-ylsulfanyl-ethanone::1-[1-(furan-2-ylmethyl)-2,5-dimethylpyrrol-3-yl]-2-pyrimidin-2-ylsulfanylethanone::MLS000770557::SMR000375854::cid_2083029 Oxysterols receptor LXR-beta 67511 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115034&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2083029 252664493 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238951 CSc1ccc(CN=Nc2ccc(Cl)c(c2)C(O)=O)cc1 InChI=1S/C15H13ClN2O2S/c1-21-12-5-2-10(3-6-12)9-17-18-11-4-7-14(16)13(8-11)15(19)20/h2-8H,9H2,1H3,(H,19,20) WTSQAKFNXVWALA-UHFFFAOYSA-N 49991 2-chloranyl-5-[2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[(N''E)-N''-[4-(methylthio)benzylidene]hydrazino]benzoic acid::2-chloro-5-[(N'E)-N'-[4-(methylthio)benzylidene]hydrazino]benzoic acid::2-chloro-5-[2-[(4-methylsulfanylphenyl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[2-[[4-(methylthio)phenyl]methylidene]hydrazinyl]benzoic acid::2-chloro-5-[N'-[4-(methylthio)benzylidene]hydrazino]benzoic acid::MLS000760472::SMR000369743::cid_4122527 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49991&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896873 252630265 ZINC36211897 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238952 Cc1ccc(cc1Cl)-n1ncc2ccccc2c1=O InChI=1S/C15H11ClN2O/c1-10-6-7-12(8-14(10)16)18-15(19)13-5-3-2-4-11(13)9-17-18/h2-9H,1H3 NPRSYIMJIISRSC-UHFFFAOYSA-N 115036 2-(3-chloranyl-4-methyl-phenyl)phthalazin-1-one::2-(3-chloro-4-methyl-phenyl)phthalazin-1-one::2-(3-chloro-4-methylphenyl)-1-phthalazinone::2-(3-chloro-4-methylphenyl)phthalazin-1-one::MLS001032924::SMR000363509::cid_2460931 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115036&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2460931 252664494 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238953 Cc1cccc(c1)N=Nc1cnc(N)s1 InChI=1S/C10H10N4S/c1-7-3-2-4-8(5-7)13-14-9-6-12-10(11)15-9/h2-6H,1H3,(H2,11,12) ULNIXBAKBYRJCA-UHFFFAOYSA-N 76565 MLS001018747::N-[(Z)-(2-azanylidene-1,3-thiazol-5-ylidene)amino]-3-methyl-aniline::N-[(Z)-(2-imino-1,3-thiazol-5-ylidene)amino]-3-methylaniline::N-[(Z)-(2-imino-5-thiazolylidene)amino]-3-methylaniline::SMR000363211::[(Z)-(2-imino-3-thiazolin-5-ylidene)amino]-(m-tolyl)amine::cid_6418684 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76565&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6418684 252653743 ZINC13119584 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238954 Cc1ccc2N=C(CC(=Nc2c1)c1ccccc1)C(Cl)Cl InChI=1S/C17H14Cl2N2/c1-11-7-8-13-15(9-11)21-14(10-16(20-13)17(18)19)12-5-3-2-4-6-12/h2-9,17H,10H2,1H3 POCZRLSDYXJPKB-UHFFFAOYSA-N 115037 2-(dichloromethyl)-7-methyl-4-phenyl-3H-1,5-benzodiazepine::2-Dichloromethyl-7-methyl-4-phenyl-3H-benzo[b][1,4]diazepine::2-[bis(chloranyl)methyl]-7-methyl-4-phenyl-3H-1,5-benzodiazepine::MLS000332968::SMR000436379::cid_941833 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115037&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 941833 252664495 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238955 Nc1nc(N)c(C#N)c(Nc2ccc(Br)cc2)n1 InChI=1S/C11H9BrN6/c12-6-1-3-7(4-2-6)16-10-8(5-13)9(14)17-11(15)18-10/h1-4H,(H5,14,15,16,17,18) YTCJLQXQKYMGIW-UHFFFAOYSA-N 115038 2,4-bis(azanyl)-6-[(4-bromophenyl)amino]pyrimidine-5-carbonitrile::2,4-diamino-6-(4-bromoanilino)-5-pyrimidinecarbonitrile::2,4-diamino-6-(4-bromoanilino)pyrimidine-5-carbonitrile::MLS000736787::SMR000528326::cid_251469 Oxysterols receptor LXR-beta 67447 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115038&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 251469 252664496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238956 O=C1Nc2ccccc2C1C=Nc1ccccc1 InChI=1S/C15H12N2O/c18-15-13(10-16-11-6-2-1-3-7-11)12-8-4-5-9-14(12)17-15/h1-10,13H,(H,17,18) QPEFRRMYOJKCMR-UHFFFAOYSA-N 115039 (3Z)-3-(anilinomethylene)oxindole::(3Z)-3-(anilinomethylidene)-1H-indol-2-one::(3Z)-3-(phenylazanylmethylidene)-1H-indol-2-one::3-[1-Phenylamino-meth-(E)-ylidene]-1,3-dihydro-indol-2-one::MLS000777404::SMR000413803::cid_5474724 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115039&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91554190 252664497 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238957 COc1cc(\C=C2\N3C=CC=CC3=C(C#N)C2=O)ccc1O InChI=1S/C17H12N2O3/c1-22-16-9-11(5-6-15(16)20)8-14-17(21)12(10-18)13-4-2-3-7-19(13)14/h2-9,20H,1H3/b14-8+ QDKMHCPYYMHDEO-RIYZIHGNSA-N 115040 (3E)-2-keto-3-vanillylidene-indolizine-1-carbonitrile::(3E)-3-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-2-oxidanylidene-indolizine-1-carbonitrile::(3E)-3-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-oxo-1-indolizinecarbonitrile::(3E)-3-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-oxoindolizine-1-carbonitrile::MLS000776195::SMR000371201::cid_6901173 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115040&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6901173 252664498 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238958 CCOC(=O)c1csc(n1)-c1sccc1Br InChI=1S/C10H8BrNO2S2/c1-2-14-10(13)7-5-16-9(12-7)8-6(11)3-4-15-8/h3-5H,2H2,1H3 FHLHPRATYFGOOC-UHFFFAOYSA-N 115041 2-(3-bromo-2-thienyl)thiazole-4-carboxylic acid ethyl ester::2-(3-bromo-2-thiophenyl)-4-thiazolecarboxylic acid ethyl ester::MLS000860210::SMR000460989::cid_2740372::ethyl 2-(3-bromanylthiophen-2-yl)-1,3-thiazole-4-carboxylate::ethyl 2-(3-bromo-2-thienyl)-1,3-thiazole-4-carboxylate::ethyl 2-(3-bromothiophen-2-yl)-1,3-thiazole-4-carboxylate Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115041&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2740372 252664499 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238959 COc1ccc2[nH]c(cc2c1)C(=O)Nc1cccc(C)n1 InChI=1S/C16H15N3O2/c1-10-4-3-5-15(17-10)19-16(20)14-9-11-8-12(21-2)6-7-13(11)18-14/h3-9,18H,1-2H3,(H,17,19,20) OABFTKPNJBYGAF-UHFFFAOYSA-N 115042 5-methoxy-N-(6-methyl-2-pyridinyl)-1H-indole-2-carboxamide::5-methoxy-N-(6-methyl-2-pyridyl)-1H-indole-2-carboxamide::5-methoxy-N-(6-methylpyridin-2-yl)-1H-indole-2-carboxamide::MLS000859321::SMR000461198::cid_2742891 Oxysterols receptor LXR-beta 67492 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115042&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2742891 252664500 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238960 CCOC(=O)c1cn[nH]c1NC(=S)Nc1ccccc1 InChI=1S/C13H14N4O2S/c1-2-19-12(18)10-8-14-17-11(10)16-13(20)15-9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H3,14,15,16,17,20) IROYJAHBNONSDB-UHFFFAOYSA-N 115043 5-(phenylthiocarbamoylamino)-1H-pyrazole-4-carboxylic acid ethyl ester::5-[[anilino(sulfanylidene)methyl]amino]-1H-pyrazole-4-carboxylic acid ethyl ester::MLS000858931::SMR000459010::cid_2816406::ethyl 5-(phenylcarbamothioylamino)-1H-pyrazole-4-carboxylate::ethyl 5-[(anilinocarbothioyl)amino]-1H-pyrazole-4-carboxylate Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115043&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2816406 252664501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238961 Brc1ccc(C=NNC(=O)c2cccs2)s1 InChI=1S/C10H7BrN2OS2/c11-9-4-3-7(16-9)6-12-13-10(14)8-2-1-5-15-8/h1-6H,(H,13,14) SCCFKSASSBYYBC-UHFFFAOYSA-N 77798 MLS000769902::N-[(5-bromanylthiophen-2-yl)methylideneamino]thiophene-2-carboxamide::N-[(5-bromo-2-thienyl)methyleneamino]thiophene-2-carboxamide::N-[(5-bromo-2-thiophenyl)methylideneamino]-2-thiophenecarboxamide::N-[(5-bromothiophen-2-yl)methylideneamino]thiophene-2-carboxamide::SMR000434730::Thiophene-2-carboxylic acid [1-(5-bromo-thiophen-2-yl)-meth-(E)-ylidene]-hydrazide::cid_574108 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77798&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 574108 252654704 ZINC18152766 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238962 Clc1ccc(Nc2ccc3ccccc3n2)cc1 InChI=1S/C15H11ClN2/c16-12-6-8-13(9-7-12)17-15-10-5-11-3-1-2-4-14(11)18-15/h1-10H,(H,17,18) ZHXBNPPHMUJAKW-UHFFFAOYSA-N 115044 (4-chlorophenyl)-(2-quinolyl)amine::MLS001077258::N-(4-chlorophenyl)-2-quinolinamine::N-(4-chlorophenyl)quinolin-2-amine::SMR000473041::cid_3107275 Oxysterols receptor LXR-beta 67486 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115044&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3107275 252664502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238963 Cc1nc(cs1)-c1ccc(NC(=O)c2ccc(Br)o2)cc1 InChI=1S/C15H11BrN2O2S/c1-9-17-12(8-21-9)10-2-4-11(5-3-10)18-15(19)13-6-7-14(16)20-13/h2-8H,1H3,(H,18,19) QKLDLURNVHPAKF-UHFFFAOYSA-N 115045 5-bromanyl-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]furan-2-carboxamide::5-bromo-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]-2-furamide::5-bromo-N-[4-(2-methyl-1,3-thiazol-4-yl)phenyl]furan-2-carboxamide::5-bromo-N-[4-(2-methyl-4-thiazolyl)phenyl]-2-furancarboxamide::5-bromo-N-[4-(2-methylthiazol-4-yl)phenyl]-2-furamide::MLS001178354::SMR000477842::cid_983644 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115045&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 983644 252664503 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238964 Cc1cc(ccc1O)N=Nc1ccc2ccccc2c1 InChI=1S/C17H14N2O/c1-12-10-15(8-9-17(12)20)18-19-16-7-6-13-4-2-3-5-14(13)11-16/h2-11,20H,1H3 LVDFXHJGWPGUGU-UHFFFAOYSA-N 115046 (4E)-2-methyl-4-(2-naphthalenylhydrazinylidene)-1-cyclohexa-2,5-dienone::(4E)-2-methyl-4-(2-naphthylhydrazono)cyclohexa-2,5-dien-1-one::(4E)-2-methyl-4-(naphthalen-2-ylhydrazinylidene)cyclohexa-2,5-dien-1-one::2-methyl-4-(2-naphthyldiazenyl)phenol::MLS001180990::SMR000477773::cid_23723128 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115046&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 23723128 252664504 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238965 OCc1ccc(cc1)\N=N\c1ccccc1 InChI=1S/C13H12N2O/c16-10-11-6-8-13(9-7-11)15-14-12-4-2-1-3-5-12/h1-9,16H,10H2/b15-14+ KDTXPUDCLDUROO-CCEZHUSRSA-N 115047 (4-phenylazophenyl)methanol::(4-phenyldiazenylphenyl)methanol::MLS001180998::SMR000475651::[4-(phenyldiazenyl)phenyl]methanol::cid_555490 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115047&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 555490 252664505 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238967 Cc1ccc(N=Nc2ccc(O)cc2)c(Br)c1 InChI=1S/C13H11BrN2O/c1-9-2-7-13(12(14)8-9)16-15-10-3-5-11(17)6-4-10/h2-8,17H,1H3 YIDMWLUFNVJJHD-UHFFFAOYSA-N 115049 4-[(2-bromanyl-4-methyl-phenyl)hydrazinylidene]cyclohexa-2,5-dien-1-one::4-[(2-bromo-4-methyl-phenyl)hydrazono]cyclohexa-2,5-dien-1-one::4-[(2-bromo-4-methylphenyl)diazenyl]phenol::4-[(2-bromo-4-methylphenyl)hydrazinylidene]-1-cyclohexa-2,5-dienone::4-[(2-bromo-4-methylphenyl)hydrazinylidene]cyclohexa-2,5-dien-1-one::MLS001180977::SMR000477771::cid_5368817 Oxysterols receptor LXR-beta 67478 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115049&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5368817 252664507 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238968 Cc1ccc(SCCSc2ncccn2)cc1 InChI=1S/C13H14N2S2/c1-11-3-5-12(6-4-11)16-9-10-17-13-14-7-2-8-15-13/h2-8H,9-10H2,1H3 SRWOANFVXCQHMS-UHFFFAOYSA-N 115050 2-({2-[(4-methylphenyl)thio]ethyl}thio)pyrimidine::2-[2-(4-methylphenyl)sulfanylethylsulfanyl]pyrimidine::2-[2-(p-tolylthio)ethylthio]pyrimidine::2-[2-[(4-methylphenyl)thio]ethylthio]pyrimidine::MLS001000858::SMR000497824::cid_2948897 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115050&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2948897 252664508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238969 [O-][N+](=O)c1ccc2[nH+]c3[N-]c4ccccc4[N-]c3[nH+]c2c1 InChI=1S/C14H7N5O2/c20-19(21)8-5-6-11-12(7-8)18-14-13(17-11)15-9-3-1-2-4-10(9)16-14/h1-7H/q-2/p+2 SPKVHIXEGLYZIV-UHFFFAOYSA-P 115051 3-nitro-5,12-dihydroquinoxalino[2,3-b]quinoxaline::8-nitro-5,12-dihydroquinoxalino[2,3-b]quinoxaline::MLS001163340::SMR000499522::cid_3775159 Oxysterols receptor LXR-beta 67492 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115051&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3775159 252664509 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238970 O=C(CCCc1ccccc1)NC12CC3CC(CC(C3)C1)C2 InChI=1S/C20H27NO/c22-19(8-4-7-15-5-2-1-3-6-15)21-20-12-16-9-17(13-20)11-18(10-16)14-20/h1-3,5-6,16-18H,4,7-14H2,(H,21,22) ZOPQBPNVFWRFSI-UHFFFAOYSA-N 115052 MLS001000010::N-(1-adamantyl)-4-phenyl-butanamide::N-(1-adamantyl)-4-phenyl-butyramide::N-(1-adamantyl)-4-phenylbutanamide::N-1-adamantyl-4-phenylbutanamide::SMR000497130::cid_2907426 Oxysterols receptor LXR-beta 67516 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115052&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2907426 252664510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238971 c1ccc2cc(ccc2c1)-c1nc(no1)-c1cccnc1 InChI=1S/C17H11N3O/c1-2-5-13-10-14(8-7-12(13)4-1)17-19-16(20-21-17)15-6-3-9-18-11-15/h1-11H TVVPNYVYLPHGEZ-UHFFFAOYSA-N 115053 3-[5-(2-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine::5-(2-naphthalenyl)-3-(3-pyridinyl)-1,2,4-oxadiazole::5-(2-naphthyl)-3-(3-pyridyl)-1,2,4-oxadiazole::5-naphthalen-2-yl-3-pyridin-3-yl-1,2,4-oxadiazole::MLS000999694::SMR000498906::cid_6462835 Oxysterols receptor LXR-beta 67519 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115053&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6462835 252664511 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238972 Nc1ccc(cc1)C(=O)Nc1ccccc1N InChI=1S/C13H13N3O/c14-10-7-5-9(6-8-10)13(17)16-12-4-2-1-3-11(12)15/h1-8H,14-15H2,(H,16,17) QGMGHALXLXKCBD-UHFFFAOYSA-N 115054 4-Amino-N-(2-amino-phenyl)-benzamide::4-amino-N-(2-aminophenyl)benzamide::MLS001209873::N-(2-aminophenyl)-4-azanyl-benzamide::SMR000504768::cid_42725 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115054&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42725 252664512 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238973 CS(=O)(=O)c1ccc2nc(NC(=O)Nc3ccccc3F)sc2c1 InChI=1S/C15H12FN3O3S2/c1-24(21,22)9-6-7-12-13(8-9)23-15(18-12)19-14(20)17-11-5-3-2-4-10(11)16/h2-8H,1H3,(H2,17,18,19,20) ILCYJNUFXUVUFX-UHFFFAOYSA-N 62134 1-(2-fluorophenyl)-3-(6-mesyl-1,3-benzothiazol-2-yl)urea::1-(2-fluorophenyl)-3-(6-methylsulfonyl-1,3-benzothiazol-2-yl)urea::MLS001163645::N-(2-fluorophenyl)-N'-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]urea::SMR000498638::cid_2242090 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=62134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=62134&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2242090 252641284 ZINC02889978 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238975 Cc1cc2nn(nc2cc1N)-c1ccc(F)cc1 InChI=1S/C13H11FN4/c1-8-6-12-13(7-11(8)15)17-18(16-12)10-4-2-9(14)3-5-10/h2-7H,15H2,1H3 IGNZBKSODFTDHY-UHFFFAOYSA-N 115056 2-(4-Fluoro-phenyl)-6-methyl-2H-benzotriazol-5-ylamine::2-(4-fluorophenyl)-6-methyl-5-benzotriazolamine::2-(4-fluorophenyl)-6-methyl-benzotriazol-5-amine::2-(4-fluorophenyl)-6-methylbenzotriazol-5-amine::MLS001210244::SMR000523818::[2-(4-fluorophenyl)-6-methyl-benzotriazol-5-yl]amine::cid_822280 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115056&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 822280 252664514 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238976 Clc1ccccc1\C=C\C(=O)Nc1ccccc1 InChI=1S/C15H12ClNO/c16-14-9-5-4-6-12(14)10-11-15(18)17-13-7-2-1-3-8-13/h1-11H,(H,17,18)/b11-10+ SPGGGKNPDWVLRC-ZHACJKMWSA-N 77817 (E)-3-(2-chlorophenyl)-N-phenyl-2-propenamide::(E)-3-(2-chlorophenyl)-N-phenyl-acrylamide::(E)-3-(2-chlorophenyl)-N-phenyl-prop-2-enamide::(E)-3-(2-chlorophenyl)-N-phenylprop-2-enamide::MLS000859034::N1-phenyl-3-(2-chlorophenyl)acrylamide::SMR000459213::cid_737170 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77817&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 737170 252654708 ZINC05015656 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238977 CCOc1ccc(cc1)-c1[n+]([O-])c2ccccc2n(O)c1=O InChI=1S/C16H14N2O4/c1-2-22-12-9-7-11(8-10-12)15-16(19)18(21)14-6-4-3-5-13(14)17(15)20/h3-10,21H,2H2,1H3 MNTAUQXUFRYRDE-UHFFFAOYSA-N 115057 1-hydroxy-4-oxido-3-p-phenetyl-quinoxalin-4-ium-2-one::3-(4-ethoxyphenyl)-1-hydroxy-4-oxido-2-quinoxalin-4-iumone::3-(4-ethoxyphenyl)-1-hydroxy-4-oxidoquinoxalin-4-ium-2-one::3-(4-ethoxyphenyl)-4-oxidanidyl-1-oxidanyl-quinoxalin-4-ium-2-one::MLS001164235::SMR000539699::cid_948254 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115057&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 948254 252664515 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238978 Brc1ccc(o1)-c1noc(n1)-c1ccccn1 InChI=1S/C11H6BrN3O2/c12-9-5-4-8(16-9)10-14-11(17-15-10)7-3-1-2-6-13-7/h1-6H DBSUFYRXXVOXJQ-UHFFFAOYSA-N 115058 2-[3-(5-bromo-2-furyl)-1,2,4-oxadiazol-5-yl]pyridine::3-(5-bromanylfuran-2-yl)-5-pyridin-2-yl-1,2,4-oxadiazole::3-(5-bromo-2-furanyl)-5-(2-pyridinyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(2-pyridyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-pyridin-2-yl-1,2,4-oxadiazole::MLS001202032::SMR000565160::cid_718328 Oxysterols receptor LXR-beta 67498 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115058&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 718328 252664516 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238979 COc1cccc(\C=C\c2ccc3cccc(O)c3n2)c1 InChI=1S/C18H15NO2/c1-21-16-6-2-4-13(12-16)8-10-15-11-9-14-5-3-7-17(20)18(14)19-15/h2-12,20H,1H3/b10-8+ SADQNNIVDUABSE-CSKARUKUSA-N 50271181 2-(3-methoxystyryl)quinolin-8-ol::CHEMBL488140::cid_5731702 Oxysterols receptor LXR-beta 67470 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50271181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50271181&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5731702 104116110 CHEMBL488140 ZINC04140786 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238980 CSc1ccccc1-c1nc(no1)-c1ccncc1 InChI=1S/C14H11N3OS/c1-19-12-5-3-2-4-11(12)14-16-13(17-18-14)10-6-8-15-9-7-10/h2-9H,1H3 KQNLSBFRXHXIFO-UHFFFAOYSA-N 76687 4-{5-[2-(methylsulfanyl)phenyl]-1,2,4-oxadiazol-3-yl}pyridine::5-(2-methylsulfanylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole::5-[2-(methylthio)phenyl]-3-(4-pyridyl)-1,2,4-oxadiazole::5-[2-(methylthio)phenyl]-3-pyridin-4-yl-1,2,4-oxadiazole::MLS001165303::SMR000549795::cid_1486780 Oxysterols receptor LXR-beta 67486 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76687&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1486780 252653864 ZINC01400994 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238981 Clc1ccc(cc1)-c1cn2cc(Cl)ccc2n1 InChI=1S/C13H8Cl2N2/c14-10-3-1-9(2-4-10)12-8-17-7-11(15)5-6-13(17)16-12/h1-8H CFINUJBABHRHDT-UHFFFAOYSA-N 114931 6-chloranyl-2-(4-chlorophenyl)imidazo[1,2-a]pyridine::6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine::MLS001166240::SMR000549995::cid_717647 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114931&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 717647 252664393 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238982 Nc1c(cnc2c(cnn12)-c1ccc(F)cc1)-c1cccs1 InChI=1S/C16H11FN4S/c17-11-5-3-10(4-6-11)12-9-20-21-15(18)13(8-19-16(12)21)14-2-1-7-22-14/h1-9H,18H2 ZPBHTNCLIWHQBB-UHFFFAOYSA-N 96015 3-(4-fluorophenyl)-6-(2-thienyl)pyrazolo[1,5-a]pyrimidin-7-amine::3-(4-fluorophenyl)-6-thiophen-2-yl-7-pyrazolo[1,5-a]pyrimidinamine::3-(4-fluorophenyl)-6-thiophen-2-yl-pyrazolo[1,5-a]pyrimidin-7-amine::3-(4-fluorophenyl)-6-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-amine::MLS001165963::SMR000550229::[3-(4-fluorophenyl)-6-(2-thienyl)pyrazolo[1,5-a]pyrimidin-7-yl]amine::cid_1474449 Oxysterols receptor LXR-beta 67517 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1474449 164037259 ZINC01386218 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238983 Cc1ccc(cc1)-c1onc2ccc(cc12)C(O)=O InChI=1S/C15H11NO3/c1-9-2-4-10(5-3-9)14-12-8-11(15(17)18)6-7-13(12)16-19-14/h2-8H,1H3,(H,17,18) HLSBMOWPXCBDEU-UHFFFAOYSA-N 115059 3-(4-methylphenyl)-2,1-benzisoxazole-5-carboxylic acid::3-(4-methylphenyl)-2,1-benzoxazole-5-carboxylic acid::3-(p-tolyl)anthranil-5-carboxylic acid::MLS001199620::SMR000560152::cid_17015159 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115059&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17015159 252664517 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238984 COc1ccc(Nc2nccc(n2)-c2cccc(N)c2)cc1 InChI=1S/C17H16N4O/c1-22-15-7-5-14(6-8-15)20-17-19-10-9-16(21-17)12-3-2-4-13(18)11-12/h2-11H,18H2,1H3,(H,19,20,21) UYPUJNKDIZFXSD-UHFFFAOYSA-N 115060 4-(3-aminophenyl)-N-(4-methoxyphenyl)-2-pyrimidinamine::4-(3-aminophenyl)-N-(4-methoxyphenyl)pyrimidin-2-amine::MLS001199466::SMR000560288::[4-(3-aminophenyl)pyrimidin-2-yl]-(4-methoxyphenyl)amine::cid_20855152 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115060&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 20855152 252664518 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238985 Oc1cccc(\C=C\c2ccc3cccc(O)c3n2)c1 InChI=1S/C17H13NO2/c19-15-5-1-3-12(11-15)7-9-14-10-8-13-4-2-6-16(20)17(13)18-14/h1-11,19-20H/b9-7+ ZGCNQHDVSASYMK-VQHVLOKHSA-N 114932 2-[(E)-2-(3-hydroxyphenyl)ethenyl]-8-quinolinol::2-[(E)-2-(3-hydroxyphenyl)ethenyl]quinolin-8-ol::2-[(E)-2-(3-hydroxyphenyl)vinyl]quinolin-8-ol::MLS001196201::SMR000558527::cid_5837141 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114932&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5837141 252664394 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238986 Cc1cc2ncc(nc2cc1C)-c1ccccc1 InChI=1S/C16H14N2/c1-11-8-14-15(9-12(11)2)18-16(10-17-14)13-6-4-3-5-7-13/h3-10H,1-2H3 FQNCLVJEQCJWSU-UHFFFAOYSA-N 33408 AG1295::CHEMBL7724::cid_2048 Oxysterols receptor LXR-beta 67490 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33408&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2048 85267026 CHEMBL7724 5914 ZINC00257983 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238987 Oc1ccccc1-c1cc([nH]n1)-c1ccc(Cl)cc1 InChI=1S/C15H11ClN2O/c16-11-7-5-10(6-8-11)13-9-14(18-17-13)12-3-1-2-4-15(12)19/h1-9,19H,(H,17,18) ZXVNJVRABSCRGU-UHFFFAOYSA-N 114933 (6Z)-6-[5-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6Z)-6-[5-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[5-(4-chlorophenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::MLS001182178::SMR000567869::cid_5333851 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114933&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5333851 252664395 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238988 N(c1nc(ns1)-c1ccccc1)c1ccccc1 InChI=1S/C14H11N3S/c1-3-7-11(8-4-1)13-16-14(18-17-13)15-12-9-5-2-6-10-12/h1-10H,(H,15,16,17) RMFQIIXCTLNZRC-UHFFFAOYSA-N 76702 MLS001193335::N,3-diphenyl-1,2,4-thiadiazol-5-amine::SMR000590015::cid_8122161::phenyl-(3-phenyl-1,2,4-thiadiazol-5-yl)amine Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 8122161 252653879 ZINC06962136 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238989 Cc1csc(NC(=O)c2ccc3ccccc3n2)n1 InChI=1S/C14H11N3OS/c1-9-8-19-14(15-9)17-13(18)12-7-6-10-4-2-3-5-11(10)16-12/h2-8H,1H3,(H,15,17,18) ZXLDSLCUIHEUDZ-UHFFFAOYSA-N 76709 MLS001177468::N-(4-methyl-1,3-thiazol-2-yl)quinoline-2-carboxamide::N-(4-methyl-2-thiazolyl)-2-quinolinecarboxamide::N-(4-methylthiazol-2-yl)quinaldamide::SMR000588905::cid_2105353 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76709&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2105353 252653886 ZINC02642555 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238990 Cc1cc(NC(=O)CSc2nc3CCCc3cc2C#N)no1 InChI=1S/C15H14N4O2S/c1-9-5-13(19-21-9)18-14(20)8-22-15-11(7-16)6-10-3-2-4-12(10)17-15/h5-6H,2-4,8H2,1H3,(H,18,19,20) RZVWYJJYGVDSHM-UHFFFAOYSA-N 72976 2-[(3-cyano-1-pyrindan-2-yl)thio]-N-(5-methylisoxazol-3-yl)acetamide::2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)sulfanyl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide::2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)sulfanyl]-N-(5-methyl-1,2-oxazol-3-yl)ethanamide::2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio]-N-(5-methyl-3-isoxazolyl)acetamide::MLS000948010::SMR000620232::cid_4046943 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72976&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4046943 252650226 ZINC00099230 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238991 Cc1cnc(NC(=O)COc2ccc3CCCc3c2)s1 InChI=1S/C15H16N2O2S/c1-10-8-16-15(20-10)17-14(18)9-19-13-6-5-11-3-2-4-12(11)7-13/h5-8H,2-4,9H2,1H3,(H,16,17,18) KUBIMESJEMVBTH-UHFFFAOYSA-N 115061 2-(2,3-dihydro-1H-inden-5-yloxy)-N-(5-methyl-1,3-thiazol-2-yl)acetamide::2-(2,3-dihydro-1H-inden-5-yloxy)-N-(5-methyl-1,3-thiazol-2-yl)ethanamide::2-(2,3-dihydro-1H-inden-5-yloxy)-N-(5-methyl-2-thiazolyl)acetamide::2-indan-5-yloxy-N-(5-methylthiazol-2-yl)acetamide::MLS001071928::SMR000671611::cid_2678142 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2678142 252664519 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238992 CC(C)c1cc(CNC(=O)c2cc(COc3cc(C)c(Cl)c(C)c3)on2)on1 InChI=1S/C20H22ClN3O4/c1-11(2)17-7-15(27-23-17)9-22-20(25)18-8-16(28-24-18)10-26-14-5-12(3)19(21)13(4)6-14/h5-8,11H,9-10H2,1-4H3,(H,22,25) HSQNKCTXNXJGKS-UHFFFAOYSA-N 115062 5-[(4-chloranyl-3,5-dimethyl-phenoxy)methyl]-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]-1,2-oxazole-3-carboxamide::5-[(4-chloro-3,5-dimethyl-phenoxy)methyl]-N-[(3-isopropylisoxazol-5-yl)methyl]isoxazole-3-carboxamide::5-[(4-chloro-3,5-dimethylphenoxy)methyl]-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]-1,2-oxazole-3-carboxamide::5-[(4-chloro-3,5-dimethylphenoxy)methyl]-N-[(3-propan-2-yl-5-isoxazolyl)methyl]-3-isoxazolecarboxamide::MLS001100869::SMR000670019::cid_24791023 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115062&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24791023 252664520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238993 Fc1ccccc1-c1cc(on1)C(=O)NCC1CCCO1 InChI=1S/C15H15FN2O3/c16-12-6-2-1-5-11(12)13-8-14(21-18-13)15(19)17-9-10-4-3-7-20-10/h1-2,5-6,8,10H,3-4,7,9H2,(H,17,19) RVXJZUKMGCVBLR-UHFFFAOYSA-N 115063 3-(2-fluorophenyl)-N-(2-oxolanylmethyl)-5-isoxazolecarboxamide::3-(2-fluorophenyl)-N-(oxolan-2-ylmethyl)-1,2-oxazole-5-carboxamide::3-(2-fluorophenyl)-N-(tetrahydrofurfuryl)isoxazole-5-carboxamide::MLS001117105::SMR000627165::cid_17096079 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115063&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17096079 252664521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238994 CC1CCN(CCSc2ccc(C)cc2)C(=O)CC1 InChI=1S/C16H23NOS/c1-13-3-6-15(7-4-13)19-12-11-17-10-9-14(2)5-8-16(17)18/h3-4,6-7,14H,5,8-12H2,1-2H3 FKGRAOXAINTQBT-UHFFFAOYSA-N 115064 5-methyl-1-[2-(4-methylphenyl)sulfanylethyl]azepan-2-one::5-methyl-1-[2-(p-tolylthio)ethyl]azepan-2-one::5-methyl-1-[2-[(4-methylphenyl)thio]ethyl]-2-azepanone::MLS000889883::SMR000674011::cid_24793608 Oxysterols receptor LXR-beta 67487 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115064&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24793608 252664522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238995 Cc1ccnc(NC(=O)C2CCN(CC2)S(=O)(=O)c2c(C)c(C)cc(C)c2C)c1 InChI=1S/C22H29N3O3S/c1-14-6-9-23-20(12-14)24-22(26)19-7-10-25(11-8-19)29(27,28)21-17(4)15(2)13-16(3)18(21)5/h6,9,12-13,19H,7-8,10-11H2,1-5H3,(H,23,24,26) MZDTXKPSRGVGCR-UHFFFAOYSA-N 115065 MLS001077534::N-(4-methyl-2-pyridinyl)-1-(2,3,5,6-tetramethylphenyl)sulfonyl-4-piperidinecarboxamide::N-(4-methyl-2-pyridyl)-1-(2,3,5,6-tetramethylphenyl)sulfonyl-isonipecotamide::N-(4-methylpyridin-2-yl)-1-(2,3,5,6-tetramethylphenyl)sulfonyl-piperidine-4-carboxamide::N-(4-methylpyridin-2-yl)-1-(2,3,5,6-tetramethylphenyl)sulfonylpiperidine-4-carboxamide::SMR000711193::cid_24816782 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24816782 252664523 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238996 Cc1ccnc(NC(=O)CCNS(=O)(=O)c2ccc(C)c(C)c2)c1 InChI=1S/C17H21N3O3S/c1-12-6-8-18-16(10-12)20-17(21)7-9-19-24(22,23)15-5-4-13(2)14(3)11-15/h4-6,8,10-11,19H,7,9H2,1-3H3,(H,18,20,21) QSUUIHSTDKKWOA-UHFFFAOYSA-N 115066 3-[(3,4-dimethylphenyl)sulfonylamino]-N-(4-methyl-2-pyridinyl)propanamide::3-[(3,4-dimethylphenyl)sulfonylamino]-N-(4-methyl-2-pyridyl)propionamide::3-[(3,4-dimethylphenyl)sulfonylamino]-N-(4-methylpyridin-2-yl)propanamide::MLS001078764::SMR000711202::cid_17505658 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17505658 252664524 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238997 Brc1ccc(o1)C(=O)Nc1ccc2ccccc2c1 InChI=1S/C15H10BrNO2/c16-14-8-7-13(19-14)15(18)17-12-6-5-10-3-1-2-4-11(10)9-12/h1-9H,(H,17,18) NLAQCTYPUSFWMR-UHFFFAOYSA-N 115067 5-bromanyl-N-naphthalen-2-yl-furan-2-carboxamide::5-bromo-N-(2-naphthalenyl)-2-furancarboxamide::5-bromo-N-(2-naphthyl)-2-furamide::5-bromo-N-naphthalen-2-ylfuran-2-carboxamide::MLS001123663::SMR000658679::cid_765392 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115067&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 765392 252664525 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238998 CCc1cc(sc1C)C(=O)Nc1ncccc1O InChI=1S/C13H14N2O2S/c1-3-9-7-11(18-8(9)2)13(17)15-12-10(16)5-4-6-14-12/h4-7,16H,3H2,1-2H3,(H,14,15,17) IKCSSRDSTDUSJA-UHFFFAOYSA-N 115068 4-ethyl-5-methyl-N-(3-oxidanylpyridin-2-yl)thiophene-2-carboxamide::4-ethyl-N-(3-hydroxy-2-pyridinyl)-5-methyl-2-thiophenecarboxamide::4-ethyl-N-(3-hydroxy-2-pyridyl)-5-methyl-thiophene-2-carboxamide::4-ethyl-N-(3-hydroxypyridin-2-yl)-5-methylthiophene-2-carboxamide::MLS001141901::SMR000688411::cid_24239799 Oxysterols receptor LXR-beta 67512 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115068&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24239799 252664526 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238999 Fc1ccccc1COc1ccc(\C=C2/C(=O)N=C3SC(CC(=O)N4CCOCC4)=NN3C2=N)cc1 InChI=1S/C25H22FN5O4S/c26-20-4-2-1-3-17(20)15-35-18-7-5-16(6-8-18)13-19-23(27)31-25(28-24(19)33)36-21(29-31)14-22(32)30-9-11-34-12-10-30/h1-8,13,27H,9-12,14-15H2/b19-13-,27-23? VIFLKBMBVPXIFY-XGCFFSCVSA-N 115069 (6Z)-5-azanylidene-6-[[4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::(6Z)-6-[4-(2-fluorobenzyl)oxybenzylidene]-5-imino-2-(2-keto-2-morpholino-ethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::(6Z)-6-[[4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-5-imino-2-(2-morpholin-4-yl-2-oxoethyl)-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::(6Z)-6-[[4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-5-imino-2-[2-(4-morpholinyl)-2-oxoethyl]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one::MLS001147864::SMR000647043::cid_5824575 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115069&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5824575 252664527 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239000 CCc1sc(cc1C)C(=O)Nc1ncccc1O InChI=1S/C13H14N2O2S/c1-3-10-8(2)7-11(18-10)13(17)15-12-9(16)5-4-6-14-12/h4-7,16H,3H2,1-2H3,(H,14,15,17) BYZMKNREIRLNCQ-UHFFFAOYSA-N 115070 5-ethyl-4-methyl-N-(3-oxidanylpyridin-2-yl)thiophene-2-carboxamide::5-ethyl-N-(3-hydroxy-2-pyridinyl)-4-methyl-2-thiophenecarboxamide::5-ethyl-N-(3-hydroxy-2-pyridyl)-4-methyl-thiophene-2-carboxamide::5-ethyl-N-(3-hydroxypyridin-2-yl)-4-methylthiophene-2-carboxamide::MLS001157712::SMR000688410::cid_24819635 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24819635 252664528 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239001 Cc1cc2nc([nH]c2cc1C)-c1cccnc1SCC(=O)NCc1ccco1 InChI=1S/C21H20N4O2S/c1-13-9-17-18(10-14(13)2)25-20(24-17)16-6-3-7-22-21(16)28-12-19(26)23-11-15-5-4-8-27-15/h3-10H,11-12H2,1-2H3,(H,23,26)(H,24,25) BFJFBFZUMCMFKG-UHFFFAOYSA-N 115071 2-[3-(5,6-Dimethyl-1H-benzoimidazol-2-yl)-pyridin-2-ylsulfanyl]-N-furan-2-ylmethyl-acetamide::2-[3-(5,6-dimethyl-1H-benzimidazol-2-yl)pyridin-2-yl]sulfanyl-N-(furan-2-ylmethyl)acetamide::2-[3-(5,6-dimethyl-1H-benzimidazol-2-yl)pyridin-2-yl]sulfanyl-N-(furan-2-ylmethyl)ethanamide::2-[[3-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]-N-(2-furanylmethyl)acetamide::2-[[3-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridyl]thio]-N-(2-furfuryl)acetamide::MLS001385447::SMR000007837::cid_653562 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 653562 252664529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239002 C(=C/n1nnc2ccccc12)\c1ccccn1 InChI=1S/C13H10N4/c1-2-7-13-12(6-1)15-16-17(13)10-8-11-5-3-4-9-14-11/h1-10H/b10-8+ UMOVCZMOBGPKME-CSKARUKUSA-N 115072 1-[(E)-2-(2-pyridinyl)ethenyl]benzotriazole::1-[(E)-2-(2-pyridyl)vinyl]benzotriazole::1-[(E)-2-pyridin-2-ylethenyl]benzotriazole::MLS001243444::SMR000841586::cid_24892260 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24892260 252664530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239003 Oc1cccnc1NC(=O)c1ccc(cc1)C(=O)c1ccccc1 InChI=1S/C19H14N2O3/c22-16-7-4-12-20-18(16)21-19(24)15-10-8-14(9-11-15)17(23)13-5-2-1-3-6-13/h1-12,22H,(H,20,21,24) JWQRXWUNCADMIE-UHFFFAOYSA-N 115073 4-benzoyl-N-(3-hydroxy-2-pyridinyl)benzamide::4-benzoyl-N-(3-hydroxy-2-pyridyl)benzamide::4-benzoyl-N-(3-hydroxypyridin-2-yl)benzamide::MLS001138688::N-(3-oxidanylpyridin-2-yl)-4-(phenylcarbonyl)benzamide::SMR000710070::cid_18109372 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18109372 252664531 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239004 COc1ccc2oc(C(=O)Nc3nccs3)c(C)c2c1 InChI=1S/C14H12N2O3S/c1-8-10-7-9(18-2)3-4-11(10)19-12(8)13(17)16-14-15-5-6-20-14/h3-7H,1-2H3,(H,15,16,17) ASEAPAQCRCSWJA-UHFFFAOYSA-N 62519 5-methoxy-3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide::5-methoxy-3-methyl-N-(2-thiazolyl)-2-benzofurancarboxamide::5-methoxy-3-methyl-N-thiazol-2-yl-coumarilamide::MLS001161559::SMR000715157::cid_2679217 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=62519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=62519&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2679217 252641647 ZINC03561935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239005 CCCCCc1nnc(NC(=O)C2=COCCO2)s1 InChI=1S/C12H17N3O3S/c1-2-3-4-5-10-14-15-12(19-10)13-11(16)9-8-17-6-7-18-9/h8H,2-7H2,1H3,(H,13,15,16) HZAVOMKOIGBUNH-UHFFFAOYSA-N 115074 MLS001128159::N-(5-amyl-1,3,4-thiadiazol-2-yl)-2,3-dihydro-p-dioxin-5-carboxamide::N-(5-pentyl-1,3,4-thiadiazol-2-yl)-2,3-dihydro-1,4-dioxin-5-carboxamide::N-(5-pentyl-1,3,4-thiadiazol-2-yl)-2,3-dihydro-1,4-dioxine-5-carboxamide::SMR000713320::cid_18077761 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18077761 252664532 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239006 Oc1cccnc1NC(=O)c1cc2ccccc2o1 InChI=1S/C14H10N2O3/c17-10-5-3-7-15-13(10)16-14(18)12-8-9-4-1-2-6-11(9)19-12/h1-8,17H,(H,15,16,18) BAXKHKJVIHZIDW-UHFFFAOYSA-N 115075 MLS001138783::N-(3-hydroxy-2-pyridinyl)-2-benzofurancarboxamide::N-(3-hydroxy-2-pyridyl)coumarilamide::N-(3-hydroxypyridin-2-yl)-1-benzofuran-2-carboxamide::N-(3-oxidanylpyridin-2-yl)-1-benzofuran-2-carboxamide::SMR000710078::cid_24982228 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24982228 252664533 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239007 NC(NC(=O)c1nc(Cl)c(N)nc1N)=Nc1ccccc1 InChI=1S/C12H12ClN7O/c13-8-10(15)19-9(14)7(18-8)11(21)20-12(16)17-6-4-2-1-3-5-6/h1-5H,(H4,14,15,19)(H3,16,17,20,21) NIOHELZQFBGCEO-UHFFFAOYSA-N 115076 3,5-bis(azanyl)-N-[azanyl(phenylazanyl)methylidene]-6-chloranyl-pyrazine-2-carboxamide;methanesulfonic acid::3,5-diamino-N-[amino(anilino)methylene]-6-chloro-pyrazinamide;mesylic acid::3,5-diamino-N-[amino(anilino)methylidene]-6-chloro-2-pyrazinecarboxamide;methanesulfonic acid::3,5-diamino-N-[amino(anilino)methylidene]-6-chloropyrazine-2-carboxamide;methanesulfonic acid::CHEMBL211502::MLS002172443::Phenamil methanesulfonate salt::SMR000326941::cid_9604979 Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4755 252664534 CHEMBL211502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239008 CC1CCC(CC1)NC(=O)c1cccn1C InChI=1S/C13H20N2O/c1-10-5-7-11(8-6-10)14-13(16)12-4-3-9-15(12)2/h3-4,9-11H,5-8H2,1-2H3,(H,14,16) ATUVXHWHDWZCHS-UHFFFAOYSA-N 115077 1-methyl-N-(4-methylcyclohexyl)-2-pyrrolecarboxamide::1-methyl-N-(4-methylcyclohexyl)pyrrole-2-carboxamide::MLS002180256::SMR001269286::cid_25161651 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25161651 252664535 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239009 Clc1ccccc1Nc1nc2ccccc2o1 InChI=1S/C13H9ClN2O/c14-9-5-1-2-6-10(9)15-13-16-11-7-3-4-8-12(11)17-13/h1-8H,(H,15,16) YCVGAYXIQCGTFE-UHFFFAOYSA-N 115078 1,3-benzoxazol-2-yl-(2-chlorophenyl)amine::MLS001359760::N-(2-chlorophenyl)-1,3-benzoxazol-2-amine::SMR001224462::cid_714839 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 714839 252664536 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239010 CC1CCc2c(C1)sc(NC(=O)C1=COCCO1)c2C(N)=O InChI=1S/C15H18N2O4S/c1-8-2-3-9-11(6-8)22-15(12(9)13(16)18)17-14(19)10-7-20-4-5-21-10/h7-8H,2-6H2,1H3,(H2,16,18)(H,17,19) GVZPXLRJSGCMBS-UHFFFAOYSA-N 115079 MLS002180030::N-(3-aminocarbonyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2,3-dihydro-1,4-dioxine-5-carboxamide::N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2,3-dihydro-1,4-dioxin-5-carboxamide::N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2,3-dihydro-1,4-dioxine-5-carboxamide::N-(3-carbamoyl-6-methyl-4,5,6,7-tetrahydrobenzothiophen-2-yl)-2,3-dihydro-p-dioxin-5-carboxamide::SMR001269060::cid_4390429 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4390429 252664537 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239011 C1[C@@H](N=C2Sc3ccccc3N12)c1ccccc1 InChI=1S/C15H12N2S/c1-2-6-11(7-3-1)12-10-17-13-8-4-5-9-14(13)18-15(17)16-12/h1-9,12H,10H2/t12-/m1/s1 YGCWPCVAVSIFLO-GFCCVEGCSA-N 115080 (2S)-2-phenyl-1,2-dihydroimidazo[2,1-b][1,3]benzothiazole::MLS002206350::SMR001295168::cid_17747785 Oxysterols receptor LXR-beta 67135 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17747785 252664538 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239012 COc1ccc2cc(ncc2c1)-c1ccsc1 InChI=1S/C14H11NOS/c1-16-13-3-2-10-7-14(11-4-5-17-9-11)15-8-12(10)6-13/h2-9H,1H3 STOHIIPAPCWUAS-UHFFFAOYSA-N 115081 7-methoxy-3-(3-thienyl)isoquinoline::7-methoxy-3-(3-thiophenyl)isoquinoline::7-methoxy-3-thiophen-3-yl-isoquinoline::7-methoxy-3-thiophen-3-ylisoquinoline::MLS002402790::SMR001370559::cid_44142278 Oxysterols receptor LXR-beta 67528 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44142278 252664539 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239013 Cc1ccc(NC(=S)NC(=O)C2CCCC2)c(Br)c1 InChI=1S/C14H17BrN2OS/c1-9-6-7-12(11(15)8-9)16-14(19)17-13(18)10-4-2-3-5-10/h6-8,10H,2-5H2,1H3,(H2,16,17,18,19) MTKFDODZWQPBPV-UHFFFAOYSA-N 115082 MLS002249268::N-[(2-bromanyl-4-methyl-phenyl)carbamothioyl]cyclopentanecarboxamide::N-[(2-bromo-4-methyl-phenyl)thiocarbamoyl]cyclopentanecarboxamide::N-[(2-bromo-4-methylanilino)-sulfanylidenemethyl]cyclopentanecarboxamide::N-[(2-bromo-4-methylphenyl)carbamothioyl]cyclopentanecarboxamide::SMR001316709::cid_2375679 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2375679 252664540 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239014 Cc1cc(C(=O)COC(=O)c2cccnc2Cl)c(C)n1C InChI=1S/C15H15ClN2O3/c1-9-7-12(10(2)18(9)3)13(19)8-21-15(20)11-5-4-6-17-14(11)16/h4-7H,8H2,1-3H3 PDLUZBXYMBLRCL-UHFFFAOYSA-N 96074 2-chloro-3-pyridinecarboxylic acid [2-oxo-2-(1,2,5-trimethyl-3-pyrrolyl)ethyl] ester::2-chloronicotinic acid [2-keto-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] ester::MLS002252084::SMR001314434::[2-oxidanylidene-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-chloranylpyridine-3-carboxylate::[2-oxo-2-(1,2,5-trimethylpyrrol-3-yl)ethyl] 2-chloropyridine-3-carboxylate::cid_2097500 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2097500 164037318 ZINC02634929 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239015 O=C(CSc1nnc(NCc2ccco2)s1)N1CCNC1=O InChI=1S/C12H13N5O3S2/c18-9(17-4-3-13-11(17)19)7-21-12-16-15-10(22-12)14-6-8-2-1-5-20-8/h1-2,5H,3-4,6-7H2,(H,13,19)(H,14,15) TZFNUHFQASBVGY-UHFFFAOYSA-N 115083 1-[2-[[5-(2-furanylmethylamino)-1,3,4-thiadiazol-2-yl]thio]-1-oxoethyl]-2-imidazolidinone::1-[2-[[5-(2-furfurylamino)-1,3,4-thiadiazol-2-yl]thio]acetyl]-2-imidazolidinone::1-[2-[[5-(furan-2-ylmethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]imidazolidin-2-one::1-[2-[[5-(furan-2-ylmethylamino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethanoyl]imidazolidin-2-one::MLS002251832::SMR001314205::cid_8278086 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 8278086 252664541 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239016 Cn1cccc1C(=O)OCC(=O)Nc1sccc1C#N InChI=1S/C13H11N3O3S/c1-16-5-2-3-10(16)13(18)19-8-11(17)15-12-9(7-14)4-6-20-12/h2-6H,8H2,1H3,(H,15,17) OYXLNYBHYGONCV-UHFFFAOYSA-N 115084 1-methyl-2-pyrrolecarboxylic acid [2-[(3-cyano-2-thiophenyl)amino]-2-oxoethyl] ester::1-methylpyrrole-2-carboxylic acid [2-[(3-cyano-2-thienyl)amino]-2-keto-ethyl] ester::MLS002251955::SMR000838755::[2-[(3-cyanothiophen-2-yl)amino]-2-oxidanylidene-ethyl] 1-methylpyrrole-2-carboxylate::[2-[(3-cyanothiophen-2-yl)amino]-2-oxoethyl] 1-methylpyrrole-2-carboxylate::cid_4003315 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115084&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4003315 252664542 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239017 CCCn1c2nc3ccccn3c(=O)c2cc(C(=O)OCC)\c1=N/C(=O)c1ccco1 InChI=1S/C22H20N4O5/c1-3-10-26-18-14(21(28)25-11-6-5-9-17(25)23-18)13-15(22(29)30-4-2)19(26)24-20(27)16-8-7-12-31-16/h5-9,11-13H,3-4,10H2,1-2H3/b24-19+ SOPJQJLWSNJZCY-LYBHJNIJSA-N 49089 2-(2-furoylimino)-5-keto-1-propyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylic acid ethyl ester::2-[2-furanyl(oxo)methyl]imino-5-oxo-1-propyl-3-dipyrido[1,2-d:3',4'-f]pyrimidinecarboxylic acid ethyl ester::MLS000052096::SMR000081413::cid_1251509::ethyl 2-(2-furoylimino)-5-oxo-1-propyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate::ethyl 2-(furan-2-carbonylimino)-5-oxo-1-propyldipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate::ethyl 2-(furan-2-ylcarbonylimino)-5-oxidanylidene-1-propyl-dipyrido[1,2-d:3',4'-f]pyrimidine-3-carboxylate Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49089&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1251509 252629373 ZINC37868771 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239018 Cc1ccc(NC(=S)N=C(NS(=O)(=O)c2ccccc2)c2ccccc2)cc1 InChI=1S/C21H19N3O2S2/c1-16-12-14-18(15-13-16)22-21(27)23-20(17-8-4-2-5-9-17)24-28(25,26)19-10-6-3-7-11-19/h2-15H,1H3,(H2,22,23,24,27) AQPLGRYVAWVUSY-UHFFFAOYSA-N 55453 1-(4-methylphenyl)-3-[C-phenyl-N-(phenylsulfonyl)carbonimidoyl]thiourea::1-(N-besyl-C-phenyl-carbonimidoyl)-3-(p-tolyl)thiourea::1-[(E)-N-besyl-C-phenyl-carbonimidoyl]-3-(p-tolyl)thiourea::1-[N-(benzenesulfonyl)-C-phenylcarbonimidoyl]-3-(4-methylphenyl)thiourea::1-[benzenesulfonylimino(phenyl)methyl]-3-(4-methylphenyl)thiourea::MLS000570272::SMR000150345::cid_2134365 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55453&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5639749 252635450 ZINC12514757 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239019 O=C(NNCc1ccccc1)c1ccccn1 InChI=1S/C13H13N3O/c17-13(12-8-4-5-9-14-12)16-15-10-11-6-2-1-3-7-11/h1-9,15H,10H2,(H,16,17) MAUBFEHMBSQXMM-UHFFFAOYSA-N 115086 MLS002608063::N'-(phenylmethyl)-2-pyridinecarbohydrazide::N'-(phenylmethyl)pyridine-2-carbohydrazide::N'-benzylpicolinohydrazide::N'-benzylpyridine-2-carbohydrazide::SMR001526814::cid_73101 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115086&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 73101 252664543 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239020 CCCCSc1ncnc2n(cnc12)C1CCCCO1 InChI=1S/C14H20N4OS/c1-2-3-8-20-14-12-13(15-9-16-14)18(10-17-12)11-6-4-5-7-19-11/h9-11H,2-8H2,1H3 WQBOXNLTSXJXII-UHFFFAOYSA-N 115087 6-(butylthio)-9-(2-oxanyl)purine::6-(butylthio)-9-tetrahydropyran-2-yl-purine::6-butylsulfanyl-9-(oxan-2-yl)purine::MLS002608089::SMR001526840::cid_236188 Oxysterols receptor LXR-beta 67448 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115087&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 236188 252664544 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239021 O=C(CC(=O)c1ccncc1)c1cccs1 InChI=1S/C12H9NO2S/c14-10(9-3-5-13-6-4-9)8-11(15)12-2-1-7-16-12/h1-7H,8H2 FFHNDRMNLBJSHI-UHFFFAOYSA-N 115088 1-(4-pyridyl)-3-(2-thienyl)propane-1,3-dione::1-pyridin-4-yl-3-thiophen-2-yl-propane-1,3-dione::1-pyridin-4-yl-3-thiophen-2-ylpropane-1,3-dione::MLS002608454::SMR001527202::cid_238435 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115088&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 238435 252664545 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239022 CCN(CC)S(=O)(=O)c1cc(ccc1F)C(=O)OCC(=O)Nc1ccc(cc1)-c1nc2ccc(C)cc2s1 InChI=1S/C27H26FN3O5S2/c1-4-31(5-2)38(34,35)24-15-19(9-12-21(24)28)27(33)36-16-25(32)29-20-10-7-18(8-11-20)26-30-22-13-6-17(3)14-23(22)37-26/h6-15H,4-5,16H2,1-3H3,(H,29,32) HHESFLBXVRUSCG-UHFFFAOYSA-N 49649 3-(diethylsulfamoyl)-4-fluoro-benzoic acid [2-keto-2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]ethyl] ester::3-(diethylsulfamoyl)-4-fluorobenzoic acid [2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] ester::MLS000395004::SMR000248406::[2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] 3-(diethylsulfamoyl)-4-fluorobenzoate::[2-[[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]amino]-2-oxidanylidene-ethyl] 3-(diethylsulfamoyl)-4-fluoranyl-benzoate::cid_2338024 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49649&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2338024 252629924 ZINC03219337 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239023 O=NC(CCc1ccccc1)c1ccccc1 InChI=1S/C15H15NO/c17-16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-10,15H,11-12H2 CDWDDQJXLPGASY-UHFFFAOYSA-N 115089 1,3-diphenyl-1-propanone oxime::1,3-diphenylpropan-1-one oxime::MLS002638408::N-(1,3-diphenylpropylidene)hydroxylamine::SMR001547891::cid_225534 Oxysterols receptor LXR-beta 67478 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115089&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899744 252664546 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239024 Fc1ccccc1CSc1ncnc2n(cnc12)C1CCCCO1 InChI=1S/C17H17FN4OS/c18-13-6-2-1-5-12(13)9-24-17-15-16(19-10-20-17)22(11-21-15)14-7-3-4-8-23-14/h1-2,5-6,10-11,14H,3-4,7-9H2 ZARXBQKUTQSBNW-UHFFFAOYSA-N 115090 6-[(2-fluorobenzyl)thio]-9-tetrahydropyran-2-yl-purine::6-[(2-fluorophenyl)methylsulfanyl]-9-(oxan-2-yl)purine::6-[(2-fluorophenyl)methylthio]-9-(2-oxanyl)purine::MLS002667534::SMR001557300::cid_243153 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115090&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 243153 252664547 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239025 ClCCN(CCCl)P1(=O)Nc2ccccc2N1 InChI=1S/C10H14Cl2N3OP/c11-5-7-15(8-6-12)17(16)13-9-3-1-2-4-10(9)14-17/h1-4H,5-8H2,(H2,13,14,16) LECSXMDGCYIRGA-UHFFFAOYSA-N 115091 MLS002693491::N,N-bis(2-chloroethyl)-2-oxidanylidene-1,3-dihydro-1,3,2-benzodiazaphosphol-2-amine::N,N-bis(2-chloroethyl)-2-oxo-1,3-dihydro-1,3,2-benzodiazaphosphol-2-amine::SMR001559444::bis(2-chloroethyl)-(2-keto-1,3-dihydro-1,3,2-benzodiazaphosphol-2-yl)amine::cid_248223 Oxysterols receptor LXR-beta 67517 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115091&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 248223 252664548 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239026 OCC1OC(CC1O)n1cc(Br)c(=O)[nH]c1=O InChI=1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16) WOVKYSAHUYNSMH-UHFFFAOYSA-N 50016787 5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione::5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione (c-5-bromo-2-deoxyuridine)::5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione(BrdUrd)::5-Bromo-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione(Bromodeoxyuridine)::CHEMBL277625::cid_236184 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016787&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search U33 2GRB 236184 103928155 CHEMBL277625 ZINC04534241 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239027 OCC1OC(CC1O)n1cc(I)c(=O)[nH]c1=O InChI=1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16) XQFRJNBWHJMXHO-UHFFFAOYSA-N 50016788 1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione (IDU)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione (c-5-iodo-2-deoxyuridine)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione( IDU)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione(IDU)::1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-iodo-1H-pyrimidine-2,4-dione(IdUrd)::CHEMBL268690::cid_3687 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016788&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search ID2 1KI7 3687 103928156 CHEMBL268690 ZINC17779640 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239028 Nc1ncnc2n(C3OC(CO)C(O)C3O)c(Br)c(C#N)c12 InChI=1S/C12H12BrN5O4/c13-9-4(1-14)6-10(15)16-3-17-11(6)18(9)12-8(21)7(20)5(2-19)22-12/h3,5,7-8,12,19-21H,2H2,(H2,15,16,17) VGLVPHRWFSFJJL-UHFFFAOYSA-N 97027 4-amino-6-bromo-7-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)pyrrolo[2,3-d]pyrimidine-5-carbonitrile::4-amino-6-bromo-7-[3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-pyrrolo[2,3-d]pyrimidinecarbonitrile::4-amino-6-bromo-7-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile::4-azanyl-6-bromanyl-7-[5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile::6-Bromotoyocamycin::MLS002703003::SMR001566812::cid_270861 Oxysterols receptor LXR-beta 67481 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=97027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=97027&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 270861 164038271 ZINC04824411 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239029 Nc1ccc-2c(Cc3cc(N)c(Cl)cc-23)c1 InChI=1S/C13H11ClN2/c14-12-6-11-8(5-13(12)16)3-7-4-9(15)1-2-10(7)11/h1-2,4-6H,3,15-16H2 HNVPFPLBIJCROA-UHFFFAOYSA-N 115092 (7-amino-3-chloro-9H-fluoren-2-yl)amine::3-chloranyl-9H-fluorene-2,7-diamine::3-chloro-9H-fluorene-2,7-diamine::MLS002703433::SMR001570152::cid_263564 Oxysterols receptor LXR-beta 67414 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115092&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 263564 252664549 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239030 CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O InChI=1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1 CBPJQFCAFFNICX-IBGZPJMESA-N 115093 (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-pentanoic acid::(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methyl-valeric acid::(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid::(2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-methylpentanoic acid::Fmoc-L-leucine::MLS002695993::SMR001562137::cid_1549133 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115093&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1549133 252664550 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239031 O=c1n(CCc2ccccc2)nnc2ccccc12 InChI=1S/C15H13N3O/c19-15-13-8-4-5-9-14(13)16-17-18(15)11-10-12-6-2-1-3-7-12/h1-9H,10-11H2 LNSOYWFCGVLLTC-UHFFFAOYSA-N 115094 3-(2-phenylethyl)-1,2,3-benzotriazin-4-one::3-phenethyl-1,2,3-benzotriazin-4-one::MLS002919856::SMR001797456::cid_277303 Oxysterols receptor LXR-beta 67431 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115094&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 277303 252664551 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239032 C1CN=C(O1)c1ccc(cc1)\N=N\c1ccccc1 InChI=1S/C15H13N3O/c1-2-4-13(5-3-1)17-18-14-8-6-12(7-9-14)15-16-10-11-19-15/h1-9H,10-11H2/b18-17+ KNELIOTUPCHJCS-ISLYRVAYSA-N 115095 MLS003106519::SMR001821418::[4-(2-oxazolin-2-yl)phenyl]-phenyl-diazene::[4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]-phenyl-diazene::[4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]-phenyldiazene::[4-(4,5-dihydrooxazol-2-yl)phenyl]-phenyldiazene::cid_293475 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115095&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 293475 252664552 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239033 CN(C)c1ccc(cc1)\N=N\c1nccs1 InChI=1S/C11H12N4S/c1-15(2)10-5-3-9(4-6-10)13-14-11-12-7-8-16-11/h3-8H,1-2H3/b14-13+ GYNBRTUYPVOSGE-BUHFOSPRSA-N 115096 Benzenamine, N,N-dimethyl-4-(2-thiazolylazo)-::MLS003106739::N,N-dimethyl-4-(1,3-thiazol-2-yldiazenyl)aniline::N,N-dimethyl-4-(2-thiazolylazo)aniline::SMR001821629::cid_298444::dimethyl-(4-thiazol-2-ylazophenyl)amine Oxysterols receptor LXR-beta 67406 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115096&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 298444 252664553 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239034 Nc1c(OS(=O)(=O)c2ccccc2)cccc1OS(=O)(=O)c1ccccc1 InChI=1S/C18H15NO6S2/c19-18-16(24-26(20,21)14-8-3-1-4-9-14)12-7-13-17(18)25-27(22,23)15-10-5-2-6-11-15/h1-13H,19H2 LQTOXLMJIIGBGG-UHFFFAOYSA-N 115097 MLS003115861::SMR001831427::[2-amino-3-(benzenesulfonyloxy)phenyl] benzenesulfonate::[2-azanyl-3-(phenylsulfonyloxy)phenyl] benzenesulfonate::benzenesulfonic acid (2-amino-3-besyloxy-phenyl) ester::benzenesulfonic acid [2-amino-3-(benzenesulfonyloxy)phenyl] ester::cid_328728 Oxysterols receptor LXR-beta 67478 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 328728 252664554 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239035 CCSCC(C)(C)n1[nH]c2ccccc2c1=O InChI=1S/C13H18N2OS/c1-4-17-9-13(2,3)15-12(16)10-7-5-6-8-11(10)14-15/h5-8,14H,4,9H2,1-3H3 OHRKOWRVNYKISA-UHFFFAOYSA-N 115098 2-(1-ethylsulfanyl-2-methyl-propan-2-yl)-1H-indazol-3-one::2-(1-ethylsulfanyl-2-methylpropan-2-yl)-1H-indazol-3-one::2-[1-(ethylthio)-2-methylpropan-2-yl]-1H-indazol-3-one::2-[2-(ethylthio)-1,1-dimethyl-ethyl]indazolin-3-one::MLS003151649::SMR001856244::cid_46904954 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115098&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46904954 252664555 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239036 CN(C)CCNc1ncnc2n(cnc12)[C@H]1CN(Cc2cccnc2)C[C@@H](CO)O1 InChI=1S/C20H28N8O2/c1-26(2)7-6-22-19-18-20(24-13-23-19)28(14-25-18)17-11-27(10-16(12-29)30-17)9-15-4-3-5-21-8-15/h3-5,8,13-14,16-17,29H,6-7,9-12H2,1-2H3,(H,22,23,24)/t16-,17+/m0/s1 SHRZCAMKJQZFMI-DLBZAZTESA-N 115099 MLS003120854::SMR001273231::[(2S,6R)-6-[6-[2-(dimethylamino)ethylamino]-9-purinyl]-4-(3-pyridinylmethyl)-2-morpholinyl]methanol::[(2S,6R)-6-[6-[2-(dimethylamino)ethylamino]purin-9-yl]-4-(3-pyridylmethyl)morpholin-2-yl]methanol::[(2S,6R)-6-[6-[2-(dimethylamino)ethylamino]purin-9-yl]-4-(pyridin-3-ylmethyl)morpholin-2-yl]methanol::cid_46943664 Oxysterols receptor LXR-beta 67490 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115099&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46943664 252664556 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239037 OC(c1nc(cs1)-c1cnc2ccccc2c1)c1ccccc1 InChI=1S/C19H14N2OS/c22-18(13-6-2-1-3-7-13)19-21-17(12-23-19)15-10-14-8-4-5-9-16(14)20-11-15/h1-12,18,22H MXQGDJZHLDDIMS-UHFFFAOYSA-N 115100 MLS003122278::SMR001277142::cid_46948381::phenyl-(4-quinolin-3-yl-1,3-thiazol-2-yl)methanol::phenyl-[4-(3-quinolinyl)-2-thiazolyl]methanol::phenyl-[4-(3-quinolyl)thiazol-2-yl]methanol Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115100&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46948381 252664557 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239038 Cc1cc(-c2ccncc2)n2ncc(-c3ccccc3)c2n1 InChI=1S/C18H14N4/c1-13-11-17(15-7-9-19-10-8-15)22-18(21-13)16(12-20-22)14-5-3-2-4-6-14/h2-12H,1H3 BDYLEIKJEYPCEO-UHFFFAOYSA-N 68333 5-methyl-3-phenyl-7-(4-pyridyl)pyrazolo[1,5-a]pyrimidine::5-methyl-3-phenyl-7-(4-pyridyl)pyrazolo[1,5-a]pyrimidine;2,2,2-trifluoroacetic acid::5-methyl-3-phenyl-7-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine;2,2,2-tris(fluoranyl)ethanoic acid::5-methyl-3-phenyl-7-pyridin-4-ylpyrazolo[1,5-a]pyrimidine;2,2,2-trifluoroacetic acid::SR-03000000952-1::cid_42640810 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42640811 252646517 ZINC61958530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239039 OCCN1CCN(CC1)c1cnc(cn1)-c1ccsc1 InChI=1S/C14H18N4OS/c19-7-6-17-2-4-18(5-3-17)14-10-15-13(9-16-14)12-1-8-20-11-12/h1,8-11,19H,2-7H2 NVOROOKFXAUPKA-UHFFFAOYSA-N 115102 2-[4-(5-thiophen-3-ylpyrazin-2-yl)piperazin-1-yl]ethanol::2-[4-[5-(3-thienyl)pyrazin-2-yl]piperazino]ethanol::2-[4-[5-(3-thiophenyl)-2-pyrazinyl]-1-piperazinyl]ethanol::MLS003123237::SMR001454231::cid_49778774 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115102&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49778774 252664558 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239040 CC(C)C(N)c1csc(Nc2nncc3ccccc23)n1 InChI=1S/C15H17N5S/c1-9(2)13(16)12-8-21-15(18-12)19-14-11-6-4-3-5-10(11)7-17-20-14/h3-9,13H,16H2,1-2H3,(H,18,19,20) GGSBPRXPSOAPKM-UHFFFAOYSA-N 115103 4-(1-amino-2-methylpropyl)-N-(1-phthalazinyl)-2-thiazolamine::4-(1-amino-2-methylpropyl)-N-phthalazin-1-yl-1,3-thiazol-2-amine::4-(1-azanyl-2-methyl-propyl)-N-phthalazin-1-yl-1,3-thiazol-2-amine::MLS003123755::SMR001291797::[4-(1-amino-2-methyl-propyl)thiazol-2-yl]-phthalazin-1-yl-amine::cid_49789405 Oxysterols receptor LXR-beta 67135 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115103&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49789405 252664559 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239041 CN(C)c1cccc(c1)-c1cc(Nc2ccc(O)cc2C)ncn1 InChI=1S/C19H20N4O/c1-13-9-16(24)7-8-17(13)22-19-11-18(20-12-21-19)14-5-4-6-15(10-14)23(2)3/h4-12,24H,1-3H3,(H,20,21,22) WMJMKQUQNODCMX-UHFFFAOYSA-N 115104 4-[[6-[3-(dimethylamino)phenyl]-4-pyrimidinyl]amino]-3-methylphenol::4-[[6-[3-(dimethylamino)phenyl]pyrimidin-4-yl]amino]-3-methyl-phenol::4-[[6-[3-(dimethylamino)phenyl]pyrimidin-4-yl]amino]-3-methylphenol::MLS003123197::SMR001454153::cid_49790647 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115104&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49790647 252664560 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239042 Cc1c(oc2ccccc12)C(=O)Nc1nccs1 InChI=1S/C13H10N2O2S/c1-8-9-4-2-3-5-10(9)17-11(8)12(16)15-13-14-6-7-18-13/h2-7H,1H3,(H,14,15,16) RDJWFCYOWJFLNV-UHFFFAOYSA-N 114954 3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide::3-methyl-N-(2-thiazolyl)-2-benzofurancarboxamide::3-methyl-N-thiazol-2-yl-coumarilamide::MLS001077610::SMR000715153::cid_4750125 Oxysterols receptor LXR-beta 67608 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114954&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4750125 252664416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239044 COc1ccc2oc3cc(NCCN(C)C)ccc3c(=O)c2c1 InChI=1S/C18H20N2O3/c1-20(2)9-8-19-12-4-6-14-17(10-12)23-16-7-5-13(22-3)11-15(16)18(14)21/h4-7,10-11,19H,8-9H2,1-3H3 XPEPALZZESYTMY-UHFFFAOYSA-N 115106 6-[2-(dimethylamino)ethylamino]-2-methoxy-9-xanthenone::6-[2-(dimethylamino)ethylamino]-2-methoxy-xanthen-9-one::6-[2-(dimethylamino)ethylamino]-2-methoxy-xanthone::6-[2-(dimethylamino)ethylamino]-2-methoxyxanthen-9-one::MLS003171348::SMR001875249::cid_341914 Oxysterols receptor LXR-beta 67460 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115106&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 341914 252664562 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239045 CN(C)c1ccc2c(n1)oc1ccccc1c2=O InChI=1S/C14H12N2O2/c1-16(2)12-8-7-10-13(17)9-5-3-4-6-11(9)18-14(10)15-12/h3-8H,1-2H3 KXXTUVAJDQJMJK-UHFFFAOYSA-N 115107 2-(dimethylamino)-5-[1]benzopyrano[2,3-b]pyridinone::2-(dimethylamino)chromeno[2,3-b]pyridin-5-one::5H- 1 Benzopyrano 2,3-b pyridin-5-one, 2-(Dimethylamino)-::MLS003373966::SMR002048754::cid_360210 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115107&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 360210 252664563 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239046 Cc1cc(C)n2c(NC3CCCC3)c(nc2n1)-c1cc2ccccc2o1 InChI=1S/C21H22N4O/c1-13-11-14(2)25-20(23-16-8-4-5-9-16)19(24-21(25)22-13)18-12-15-7-3-6-10-17(15)26-18/h3,6-7,10-12,16,23H,4-5,8-9H2,1-2H3 KOTKEOPVHGKCMR-UHFFFAOYSA-N 115108 2-(1-benzofuran-2-yl)-N-cyclopentyl-5,7-dimethyl-imidazo[1,2-a]pyrimidin-3-amine::2-(1-benzofuran-2-yl)-N-cyclopentyl-5,7-dimethylimidazo[1,2-a]pyrimidin-3-amine::2-(2-benzofuranyl)-N-cyclopentyl-5,7-dimethyl-3-imidazo[1,2-a]pyrimidinamine::2-(benzofuran-2-yl)-N-cyclopentyl-5,7-dimethylimidazo[1,2-a]pyrimidin-3-amine::MLS003589658::SMR002249893::[2-(benzofuran-2-yl)-5,7-dimethyl-imidazo[1,2-a]pyrimidin-3-yl]-cyclopentyl-amine::cid_53301193 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115108&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53301193 252664564 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239047 CN(C)c1cccc(c1)-c1cnc(s1)N1CCC(CC1)C(N)=O InChI=1S/C17H22N4OS/c1-20(2)14-5-3-4-13(10-14)15-11-19-17(23-15)21-8-6-12(7-9-21)16(18)22/h3-5,10-12H,6-9H2,1-2H3,(H2,18,22) QSIYOOLBRHGSSD-UHFFFAOYSA-N 115109 1-[5-[3-(dimethylamino)phenyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide;2,2,2-trifluoroacetic acid::1-[5-[3-(dimethylamino)phenyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::1-[5-[3-(dimethylamino)phenyl]-2-thiazolyl]-4-piperidinecarboxamide;2,2,2-trifluoroacetic acid::1-[5-[3-(dimethylamino)phenyl]thiazol-2-yl]isonipecotamide;2,2,2-trifluoroacetic acid::MLS002607722::SMR001522596::cid_53338831 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115109&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46907664 252664565 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239048 O=C(NC1CCC1)c1ccc(cn1)C#CC1CC1 InChI=1S/C15H16N2O/c18-15(17-13-2-1-3-13)14-9-8-12(10-16-14)7-6-11-4-5-11/h8-11,13H,1-5H2,(H,17,18) GAGAPXLUCSJVRL-UHFFFAOYSA-N 115110 MLS003874881::N-cyclobutyl-5-(2-cyclopropylethynyl)-2-pyridinecarboxamide;hydrochloride::N-cyclobutyl-5-(2-cyclopropylethynyl)picolinamide;hydrochloride::N-cyclobutyl-5-(2-cyclopropylethynyl)pyridine-2-carboxamide;hydrochloride::SMR002531665::cid_53384838 Oxysterols receptor LXR-beta 67540 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115110&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53384869 252664566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239049 CCCCCCCCN1C(=O)[C@@H](CC(=O)NCC#C)C[C@@]2([C@H](O[C@H](C=C12)C(C)C)C1CC1)C(=O)OC InChI=1S/C29H44N2O5/c1-6-8-9-10-11-12-16-31-24-18-23(20(3)4)36-26(21-13-14-21)29(24,28(34)35-5)19-22(27(31)33)17-25(32)30-15-7-2/h2,18,20-23,26H,6,8-17,19H2,1,3-5H3,(H,30,32)/t22-,23+,26+,29+/m0/s1 ZYJFYPRYFBOXTI-MLUWVZQDSA-N 115111 (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxo-3-[2-oxo-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::(3R,4aR,5R,7S)-5-cyclopropyl-7-isopropyl-2-keto-3-[2-keto-2-(propargylamino)ethyl]-1-octyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::MLS003874257::SMR002530922::cid_60156978::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxidanylidene-3-[2-oxidanylidene-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-octyl-2-oxo-3-[2-oxo-2-(prop-2-ynylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate Oxysterols receptor LXR-beta 67518 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115111&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 60156978 252664567 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239051 N#Cc1cc2ccccc2nc1SCc1ccccn1 InChI=1S/C16H11N3S/c17-10-13-9-12-5-1-2-7-15(12)19-16(13)20-11-14-6-3-4-8-18-14/h1-9H,11H2 ZSDAMVTUFIDYFC-UHFFFAOYSA-N 49189 2-(2-pyridinylmethylthio)-3-quinolinecarbonitrile::2-(2-pyridylmethylthio)quinoline-3-carbonitrile::2-(Pyridin-2-ylmethylsulfanyl)-quinoline-3-carbonitrile::2-(pyridin-2-ylmethylsulfanyl)quinoline-3-carbonitrile::MLS000076502::SMR000007876::cid_656038 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49189&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 656038 252629470 ZINC01330985 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239052 O=C1C(C(=O)c2ccccc12)c1ccc2ccccc2n1 InChI=1S/C18H11NO2/c20-17-12-6-2-3-7-13(12)18(21)16(17)15-10-9-11-5-1-4-8-14(11)19-15/h1-10,16H IZMJMCDDWKSTTK-UHFFFAOYSA-N 32227 2-(1H-quinolin-2-ylidene)indane-1,3-quinone::2-(1H-quinolin-2-ylidene)indene-1,3-dione::2-(2-quinolyl)indane-1,3-quinone::cid_5355280 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32227&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6731 252615674 ZINC03848530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239053 COc1ccc(cc1OC)-c1cn2ccccc2n1 InChI=1S/C15H14N2O2/c1-18-13-7-6-11(9-14(13)19-2)12-10-17-8-4-3-5-15(17)16-12/h3-10H,1-2H3 JGRYUQHLNWXJIZ-UHFFFAOYSA-N 114833 2-(3,4-dimethoxyphenyl)imidazo[1,2-a]pyridine;hydrobromide::MLS000037895::SMR000036046::cid_6602755 Oxysterols receptor LXR-beta 67514 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114833&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 659246 252664304 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239054 Cn1cccc1C(=O)OCc1csc(n1)-c1ccccc1 InChI=1S/C16H14N2O2S/c1-18-9-5-8-14(18)16(19)20-10-13-11-21-15(17-13)12-6-3-2-4-7-12/h2-9,11H,10H2,1H3 SWGLEZWLVBJBAG-UHFFFAOYSA-N 39548 (2-phenyl-1,3-thiazol-4-yl)methyl 1-methylpyrrole-2-carboxylate::1-methyl-2-pyrrolecarboxylic acid (2-phenyl-4-thiazolyl)methyl ester::1-methylpyrrole-2-carboxylic acid (2-phenylthiazol-4-yl)methyl ester::MLS000058002::SMR000063048::cid_2091642 Oxysterols receptor LXR-beta 67502 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39548&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2091642 252620439 ZINC02629255 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239055 O=C(Nc1ccccn1)c1ccc2ccccc2n1 InChI=1S/C15H11N3O/c19-15(18-14-7-3-4-10-16-14)13-9-8-11-5-1-2-6-12(11)17-13/h1-10H,(H,16,18,19) ZPRCRZOROVUWAJ-UHFFFAOYSA-N 38811 MLS000097807::N-(2-pyridinyl)-2-quinolinecarboxamide::N-(2-pyridyl)quinaldamide::N-pyridin-2-ylquinoline-2-carboxamide::SMR000059952::cid_761227 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38811&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 761227 252619715 ZINC00230410 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239056 CCOc1ccccc1-n1nnnc1SCc1nc2ccccc2s1 InChI=1S/C17H15N5OS2/c1-2-23-14-9-5-4-8-13(14)22-17(19-20-21-22)24-11-16-18-12-7-3-6-10-15(12)25-16/h3-10H,2,11H2,1H3 CRBWEZWLWBCXFG-UHFFFAOYSA-N 114834 2-[[(1-o-phenetyltetrazol-5-yl)thio]methyl]-1,3-benzothiazole::2-[[1-(2-ethoxyphenyl)-1,2,3,4-tetrazol-5-yl]sulfanylmethyl]-1,3-benzothiazole::2-[[1-(2-ethoxyphenyl)tetrazol-5-yl]sulfanylmethyl]-1,3-benzothiazole::2-[[[1-(2-ethoxyphenyl)-5-tetrazolyl]thio]methyl]-1,3-benzothiazole::MLS000098530::SMR000064900::cid_2613788 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114834&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2613788 252664305 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239057 CCOC(=O)N1CCC(CC1)Nc1c(-c2ccc(C)cc2)c(=O)c1=O InChI=1S/C19H22N2O4/c1-3-25-19(24)21-10-8-14(9-11-21)20-16-15(17(22)18(16)23)13-6-4-12(2)5-7-13/h4-7,14,20H,3,8-11H2,1-2H3 KSPPMIJXWVTPHT-UHFFFAOYSA-N 114835 4-[[2-(4-methylphenyl)-3,4-dioxo-1-cyclobutenyl]amino]-1-piperidinecarboxylic acid ethyl ester::4-[[3,4-diketo-2-(p-tolyl)cyclobuten-1-yl]amino]piperidine-1-carboxylic acid ethyl ester::MLS000094572::SMR000030123::cid_3238133::ethyl 4-[[2-(4-methylphenyl)-3,4-bis(oxidanylidene)cyclobuten-1-yl]amino]piperidine-1-carboxylate::ethyl 4-[[2-(4-methylphenyl)-3,4-dioxocyclobuten-1-yl]amino]piperidine-1-carboxylate::ethyl 4-{[2-(4-methylphenyl)-3,4-dioxocyclobut-1-en-1-yl]amino}piperidine-1-carboxylate Oxysterols receptor LXR-beta 67513 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114835&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3238133 252664306 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239058 O=C1C(C(=O)c2ccccc12)c1nccc2ccccc12 InChI=1S/C18H11NO2/c20-17-13-7-3-4-8-14(13)18(21)15(17)16-12-6-2-1-5-11(12)9-10-19-16/h1-10,15H KXIAYOHGMQBMRT-UHFFFAOYSA-N 38985 2-(1-isoquinolinyl)indene-1,3-dione::2-(1-isoquinolyl)indane-1,3-quinone::2-isoquinolin-1-yl-1H-indene-1,3(2H)-dione::2-isoquinolin-1-ylindene-1,3-dione::MLS000085507::SMR000020442::cid_3243985 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38985&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3243985 252619885 ZINC03908918 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239059 CCOc1ccc(cc1OC)-c1noc(COC)n1 InChI=1S/C13H16N2O4/c1-4-18-10-6-5-9(7-11(10)17-3)13-14-12(8-16-2)19-15-13/h5-7H,4,8H2,1-3H3 CCKCKNOVZGVHBQ-UHFFFAOYSA-N 49065 3-(4-ethoxy-3-methoxy-phenyl)-5-(methoxymethyl)-1,2,4-oxadiazole::3-(4-ethoxy-3-methoxyphenyl)-5-(methoxymethyl)-1,2,4-oxadiazole::MLS000100274::SMR000082317::cid_2981021 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2981021 252629349 ZINC04195608 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239060 Cc1c(oc2ccccc12)C(=O)Nc1ccccn1 InChI=1S/C15H12N2O2/c1-10-11-6-2-3-7-12(11)19-14(10)15(18)17-13-8-4-5-9-16-13/h2-9H,1H3,(H,16,17,18) PIGSACWYWBAHNK-UHFFFAOYSA-N 114836 3-methyl-N-(2-pyridinyl)-2-benzofurancarboxamide::3-methyl-N-(2-pyridyl)coumarilamide::3-methyl-N-2-pyridinyl-1-benzofuran-2-carboxamide::3-methyl-N-pyridin-2-yl-1-benzofuran-2-carboxamide::MLS000065704::SMR000080366::cid_1245473 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114836&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1245473 252664307 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239061 Oc1ccccc1-c1cc([nH]n1)-c1ccccc1Cl InChI=1S/C15H11ClN2O/c16-12-7-3-1-5-10(12)13-9-14(18-17-13)11-6-2-4-8-15(11)19/h1-9,19H,(H,17,18) WVSVHWLLYNJIRR-UHFFFAOYSA-N 49247 (6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6Z)-6-[5-(2-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[5-(2-chlorophenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::2-[5-(2-chlorophenyl)-1H-pyrazol-3-yl]phenol::MLS000060847::SMR000069712::cid_5339594 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49247&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5339594 252629528 ZINC13130589 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239062 Fc1ccc(cc1)-c1nc2-c3ccccc3Cn2n1 InChI=1S/C15H10FN3/c16-12-7-5-10(6-8-12)14-17-15-13-4-2-1-3-11(13)9-19(15)18-14/h1-8H,9H2 OTMSGGRGWSIHPW-UHFFFAOYSA-N 49255 2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindole::2-(4-fluorophenyl)-5H-[1,2,4]triazolo[5,1-a]isoindole::MLS000066641::SMR000082547::cid_1236969 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49255&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1236969 252629536 ZINC01020521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239063 CC(C)NC(=O)c1nc2ccccc2s1 InChI=1S/C11H12N2OS/c1-7(2)12-10(14)11-13-8-5-3-4-6-9(8)15-11/h3-7H,1-2H3,(H,12,14) NCLPSJQUAFVAIZ-UHFFFAOYSA-N 114837 MLS000064642::N-isopropyl-1,3-benzothiazole-2-carboxamide::N-propan-2-yl-1,3-benzothiazole-2-carboxamide::SMR000077342::cid_972324 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114837&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 972324 252664308 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239064 Cc1ccc(NCc2nc3ccccc3n2C)cc1 InChI=1S/C16H17N3/c1-12-7-9-13(10-8-12)17-11-16-18-14-5-3-4-6-15(14)19(16)2/h3-10,17H,11H2,1-2H3 UIDZOGWOSWZXKD-UHFFFAOYSA-N 49262 (1-methylbenzimidazol-2-yl)methyl-(p-tolyl)amine::4-methyl-N-[(1-methyl-1H-benzimidazol-2-yl)methyl]aniline::4-methyl-N-[(1-methyl-2-benzimidazolyl)methyl]aniline::4-methyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline::MLS000061671::SMR000070004::cid_797034 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49262&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 797034 252629543 ZINC00301578 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239065 Cc1ccc(NC(=O)c2ccc3ccccc3n2)nc1 InChI=1S/C16H13N3O/c1-11-6-9-15(17-10-11)19-16(20)14-8-7-12-4-2-3-5-13(12)18-14/h2-10H,1H3,(H,17,19,20) QOBXTKFDZSBUOW-UHFFFAOYSA-N 49263 MLS000062670::N-(5-methyl-2-pyridinyl)-2-quinolinecarboxamide::N-(5-methyl-2-pyridyl)quinaldamide::N-(5-methylpyridin-2-yl)quinoline-2-carboxamide::SMR000071207::cid_797352 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49263&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 797352 252629544 ZINC00302104 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239066 Oc1cccc(c1)-c1nc2ccccc2s1 InChI=1S/C13H9NOS/c15-10-5-3-4-9(8-10)13-14-11-6-1-2-7-12(11)16-13/h1-8,15H JIWVTDBBMGSTFI-UHFFFAOYSA-N 33577 3-(1,3-benzothiazol-2-yl)phenol::MLS000063319::SMR000074978::cid_242605 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=33577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=33577&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 242605 252616482 ZINC00520300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239067 CC1CCCCN1CCNC(=O)CC1Oc2ccccc2NC1=O InChI=1S/C18H25N3O3/c1-13-6-4-5-10-21(13)11-9-19-17(22)12-16-18(23)20-14-7-2-3-8-15(14)24-16/h2-3,7-8,13,16H,4-6,9-12H2,1H3,(H,19,22)(H,20,23) FKSRXOUJSKNUNR-UHFFFAOYSA-N 114838 2-(3-keto-4H-1,4-benzoxazin-2-yl)-N-[2-(2-methylpiperidino)ethyl]acetamide::MLS000119402::N-[2-(2-methyl-1-piperidinyl)ethyl]-2-(3-oxo-4H-1,4-benzoxazin-2-yl)acetamide::N-[2-(2-methylpiperidin-1-yl)ethyl]-2-(3-oxidanylidene-4H-1,4-benzoxazin-2-yl)ethanamide::N-[2-(2-methylpiperidin-1-yl)ethyl]-2-(3-oxo-4H-1,4-benzoxazin-2-yl)acetamide::SMR000096323::cid_5309181 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114838&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5309181 252664309 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239068 COc1ccc(cc1)-c1noc(n1)-c1ccccc1F InChI=1S/C15H11FN2O2/c1-19-11-8-6-10(7-9-11)14-17-15(20-18-14)12-4-2-3-5-13(12)16/h2-9H,1H3 DANKTKKLNXAGKW-UHFFFAOYSA-N 50293103 5-(2-fluorophenyl)-3-(4-methoxyphenyl)-1,2,4-oxadiazole::CHEMBL472929::cid_925735 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50293103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50293103&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 925735 104134654 CHEMBL472929 ZINC00515041 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239069 CCC(C)Sc1nc2c3ccccc3[nH]c2c(=O)n1C InChI=1S/C15H17N3OS/c1-4-9(2)20-15-17-12-10-7-5-6-8-11(10)16-13(12)14(19)18(15)3/h5-9,16H,4H2,1-3H3 BQVFSSLPCMGBHL-UHFFFAOYSA-N 48977 2-(butan-2-ylthio)-3-methyl-5H-pyrimido[5,4-b]indol-4-one::2-butan-2-ylsulfanyl-3-methyl-5H-pyrimido[5,4-b]indol-4-one::3-methyl-2-(sec-butylthio)-5H-pyrimid[5,4-b]indol-4-one::MLS000101323::SMR000018491::cid_3254362 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48977&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3254362 252629263 ZINC13776831 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239070 CC(=O)Nc1nc(nc(C)c1C(C)=O)-c1ccc(Cl)cc1 InChI=1S/C15H14ClN3O2/c1-8-13(9(2)20)15(18-10(3)21)19-14(17-8)11-4-6-12(16)7-5-11/h4-7H,1-3H3,(H,17,18,19,21) QDGUFSIFORBCAE-UHFFFAOYSA-N 114839 MLS000111311::N-[2-(4-chlorophenyl)-5-ethanoyl-6-methyl-pyrimidin-4-yl]ethanamide::N-[5-acetyl-2-(4-chlorophenyl)-6-methyl-4-pyrimidinyl]acetamide::N-[5-acetyl-2-(4-chlorophenyl)-6-methyl-pyrimidin-4-yl]acetamide::N-[5-acetyl-2-(4-chlorophenyl)-6-methylpyrimidin-4-yl]acetamide::SMR000107236::cid_885153 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114839&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 885153 252664310 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239071 O=c1oc(nc2sc3CCCCc3c12)-c1cc2ccccc2o1 InChI=1S/C18H13NO3S/c20-18-15-11-6-2-4-8-14(11)23-17(15)19-16(22-18)13-9-10-5-1-3-7-12(10)21-13/h1,3,5,7,9H,2,4,6,8H2 YNVYCLOWNUHMBI-UHFFFAOYSA-N 44799 2-(1-benzofuran-2-yl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d][1,3]oxazin-4-one::2-(2-benzofuranyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d][1,3]oxazin-4-one::2-(benzofuran-2-yl)-5,6,7,8-tetrahydrobenzothiopheno[2,3-d][1,3]oxazin-4-one::MLS000112646::SMR000108557::cid_2077550 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44799&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2077550 252625405 ZINC02615807 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239072 COc1ccc(cc1)-c1cn2ccc3ccccc3c2n1 InChI=1S/C18H14N2O/c1-21-15-8-6-14(7-9-15)17-12-20-11-10-13-4-2-3-5-16(13)18(20)19-17/h2-12H,1H3 ZYWYGWRRHDDHSN-UHFFFAOYSA-N 49357 2-(4-Methoxy-phenyl)-imidazo[2,1-a]isoquinoline::2-(4-methoxyphenyl)imidaz[2,1-a]isoquinoline::2-(4-methoxyphenyl)imidazo[2,1-a]isoquinoline::MLS000121240::SMR000118707::cid_746061 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49357&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 746061 252629636 ZINC00189092 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239073 O=C1C(C(=O)c2ccccc12)c1ccnc2ccccc12 InChI=1S/C18H11NO2/c20-17-13-6-1-2-7-14(13)18(21)16(17)12-9-10-19-15-8-4-3-5-11(12)15/h1-10,16H NLWBFTBOPUZRIV-UHFFFAOYSA-N 40551 2-(1H-quinolin-4-ylidene)indane-1,3-quinone::2-(1H-quinolin-4-ylidene)indene-1,3-dione::2-(4-quinolyl)indane-1,3-quinone::3-Hydroxy-2-quinolin-4-yl-inden-1-one::MLS000122777::SMR000120181::cid_5765327 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40551&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1207745 252621373 ZINC13124108 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239074 CCc1ccc2oc(nc2c1)-c1cccc(N)c1 InChI=1S/C15H14N2O/c1-2-10-6-7-14-13(8-10)17-15(18-14)11-4-3-5-12(16)9-11/h3-9H,2,16H2,1H3 CPAMZMMYEPRNLO-UHFFFAOYSA-N 48214 3-(5-Ethyl-benzooxazol-2-yl)-phenylamine::3-(5-ethyl-1,3-benzoxazol-2-yl)aniline::MLS000525240::SMR000122114::[3-(5-ethyl-1,3-benzoxazol-2-yl)phenyl]amine::cid_735963 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48214&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 735963 252628511 ZINC00154721 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239075 OC(CN1C(=O)c2ccccc2C1=O)CN1CCOCC1 InChI=1S/C15H18N2O4/c18-11(9-16-5-7-21-8-6-16)10-17-14(19)12-3-1-2-4-13(12)15(17)20/h1-4,11,18H,5-10H2 KRPPDJHRNRJDAE-UHFFFAOYSA-N 114840 2-(2-Hydroxy-3-morpholin-4-yl-propyl)-isoindole-1,3-dione::2-(2-hydroxy-3-morpholin-4-ylpropyl)isoindole-1,3-dione::2-(2-hydroxy-3-morpholino-propyl)isoindoline-1,3-quinone::2-(3-morpholin-4-yl-2-oxidanyl-propyl)isoindole-1,3-dione::2-[2-hydroxy-3-(4-morpholinyl)propyl]isoindole-1,3-dione::MLS000527606::SMR000118080::cid_3112589 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114840&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3112589 252664311 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239076 Cc1cccc(Nc2nc(cs2)-c2cccs2)n1 InChI=1S/C13H11N3S2/c1-9-4-2-6-12(14-9)16-13-15-10(8-18-13)11-5-3-7-17-11/h2-8H,1H3,(H,14,15,16) GNUGUUFOOMYNGW-UHFFFAOYSA-N 49376 (6-Methyl-pyridin-2-yl)-(4-thiophen-2-yl-thiazol-2-yl)-amine::(6-methyl-2-pyridyl)-[4-(2-thienyl)thiazol-2-yl]amine::MLS000527802::N-(6-methyl-2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine::N-(6-methylpyridin-2-yl)-4-thiophen-2-yl-1,3-thiazol-2-amine::SMR000120376::cid_973018 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49376&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 973018 252629655 ZINC00613473 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239077 O=C1C(C(=O)c2ccccc12)c1ccnc2ccccc12 InChI=1S/C18H11NO2/c20-17-13-6-1-2-7-14(13)18(21)16(17)12-9-10-19-15-8-4-3-5-11(12)15/h1-10,16H NLWBFTBOPUZRIV-UHFFFAOYSA-N 40551 2-(1H-quinolin-4-ylidene)indane-1,3-quinone::2-(1H-quinolin-4-ylidene)indene-1,3-dione::2-(4-quinolyl)indane-1,3-quinone::3-Hydroxy-2-quinolin-4-yl-inden-1-one::MLS000122777::SMR000120181::cid_5765327 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=40551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=40551&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1207745 252621373 ZINC13124108 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239078 Cc1ccc2nc([nH]c2c1)-c1sc2nc(C)ccc2c1N InChI=1S/C16H14N4S/c1-8-3-6-11-12(7-8)20-15(19-11)14-13(17)10-5-4-9(2)18-16(10)21-14/h3-7H,17H2,1-2H3,(H,19,20) JSZUFXOHXIQNRZ-UHFFFAOYSA-N 49392 6-methyl-2-(5-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-ylamine::6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)-3-thieno[2,3-b]pyridinamine::6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-amine::MLS000547128::SMR000115129::[6-methyl-2-(6-methyl-1H-benzimidazol-2-yl)thieno[2,3-b]pyridin-3-yl]amine::cid_845805 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49392&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 845805 252629671 ZINC06493799 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239079 Clc1ccc(cc1)-c1nc2-c3ccccc3Cn2n1 InChI=1S/C15H10ClN3/c16-12-7-5-10(6-8-12)14-17-15-13-4-2-1-3-11(13)9-19(15)18-14/h1-8H,9H2 YOLSZCDGNJWZDU-UHFFFAOYSA-N 49393 2-(4-chlorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindole::2-(4-chlorophenyl)-5H-[1,2,4]triazolo[5,1-a]isoindole::MLS000548467::SMR000114053::cid_134450 Oxysterols receptor LXR-beta 67480 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49393&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134450 252629672 ZINC01020522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239080 Cc1ccc2nc(cc(O)c2c1)-c1ccccc1 InChI=1S/C16H13NO/c1-11-7-8-14-13(9-11)16(18)10-15(17-14)12-5-3-2-4-6-12/h2-10H,1H3,(H,17,18) SWRQHHJAXCNFGU-UHFFFAOYSA-N 37510 6-methyl-2-phenyl-1H-quinolin-4-one::6-methyl-2-phenyl-4-quinolone::CHEMBL16223::MLS000112473::SMR000108387::cid_730810 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37510&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 730810 252618481 CHEMBL16223 ZINC08579163 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239081 COc1ccccc1-c1nc(no1)-c1ccc(Br)o1 InChI=1S/C13H9BrN2O3/c1-17-9-5-3-2-4-8(9)13-15-12(16-19-13)10-6-7-11(14)18-10/h2-7H,1H3 QLLJJRSZQXRNKB-UHFFFAOYSA-N 49399 3-(5-bromanylfuran-2-yl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furanyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromo-2-furyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::3-(5-bromofuran-2-yl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole::MLS000522326::SMR000127594::cid_717857 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49399&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 717857 252629678 ZINC00116771 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239082 Cc1ccc(CN=Nc2nnc(Cl)c3ccccc23)cc1 InChI=1S/C16H13ClN4/c1-11-6-8-12(9-7-11)10-18-20-16-14-5-3-2-4-13(14)15(17)19-21-16/h2-9H,10H2,1H3 UXXUARUEKHWPFH-UHFFFAOYSA-N 49409 (4-chlorophthalazin-1-yl)-[(4-methylbenzylidene)amino]amine::(4-chlorophthalazin-1-yl)-[(E)-(4-methylbenzylidene)amino]amine::4-chloranyl-N-[(4-methylphenyl)methylideneamino]phthalazin-1-amine::4-chloro-N-[(4-methylphenyl)methylideneamino]-1-phthalazinamine::4-chloro-N-[(4-methylphenyl)methylideneamino]phthalazin-1-amine::MLS000595232::N-(4-Chloro-phthalazin-1-yl)-N'-[1-p-tolyl-meth-(E)-ylidene]-hydrazine::SMR000149755::cid_1557748 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49409&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 90847968 252629688 ZINC33343004 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239083 Cc1nn(-c2ccc(C)cc2)c2[nH]c(=O)cc(C)c12 InChI=1S/C15H15N3O/c1-9-4-6-12(7-5-9)18-15-14(11(3)17-18)10(2)8-13(19)16-15/h4-8H,1-3H3,(H,16,19) CXHMMBSVAPYKCF-UHFFFAOYSA-N 64572 3,4-dimethyl-1-(4-methylphenyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one::3,4-dimethyl-1-(4-methylphenyl)-2H-pyrazolo[3,4-b]pyridin-6-one::3,4-dimethyl-1-(p-tolyl)-2H-pyrazolo[3,4-b]pyridin-6-one::MLS000531437::SMR000136415::cid_2224694 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64572&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2224694 252643650 ZINC08828750 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239084 COc1ccc(cc1)S(=O)(=O)Cc1ccc(o1)C(=O)NCCCN1CCc2ccccc2C1 InChI=1S/C25H28N2O5S/c1-31-21-7-10-23(11-8-21)33(29,30)18-22-9-12-24(32-22)25(28)26-14-4-15-27-16-13-19-5-2-3-6-20(19)17-27/h2-3,5-12H,4,13-18H2,1H3,(H,26,28) RBSYAGFGZNAWCQ-UHFFFAOYSA-N 114842 MLS000522630::N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-5-[(4-methoxyphenyl)sulfonylmethyl]-2-furamide::N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-5-[(4-methoxyphenyl)sulfonylmethyl]-2-furancarboxamide::N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-5-[(4-methoxyphenyl)sulfonylmethyl]furan-2-carboxamide::SMR000127897::cid_6619902 Oxysterols receptor LXR-beta 67524 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114842&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6619902 252664312 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239085 CN1\C(Sc2ccccc12)=C\C(=O)c1cccs1 InChI=1S/C14H11NOS2/c1-15-10-5-2-3-6-12(10)18-14(15)9-11(16)13-7-4-8-17-13/h2-9H,1H3/b14-9- JMBZNSQGQKVUPF-ZROIWOOFSA-N 49453 (2Z)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-(2-thienyl)ethanone::(2Z)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-thiophen-2-yl-ethanone::(2Z)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-thiophen-2-ylethanone::2-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)-1-(2-thienyl)ethanone::MLS000536852::SMR000143489::cid_1633230 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49453&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1633230 252629730 ZINC04746671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239086 CC(=Nc1cccc(C)c1)c1sc2ccccc2c1O InChI=1S/C17H15NOS/c1-11-6-5-7-13(10-11)18-12(2)17-16(19)14-8-3-4-9-15(14)20-17/h3-10,19H,1-2H3 WDGGDHCOGSHKMB-UHFFFAOYSA-N 49455 (2Z)-2-[1-(3-methylanilino)ethylidene]-1-benzothiophen-3-one::(2Z)-2-[1-(m-toluidino)ethylidene]benzothiophen-3-one::(2Z)-2-[1-[(3-methylphenyl)amino]ethylidene]-1-benzothiophen-3-one::2-[1-m-Tolylamino-eth-(Z)-ylidene]-benzo[b]thiophen-3-one::MLS000550927::SMR000145055::cid_6859005 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49455&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6859005 252629732 ZINC13471367 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239087 COc1ccc(cc1)-c1cc(n[nH]1)-c1ccccc1O InChI=1S/C16H14N2O2/c1-20-12-8-6-11(7-9-12)14-10-15(18-17-14)13-4-2-3-5-16(13)19/h2-10,19H,1H3,(H,17,18) AASRUAOBYASXDX-UHFFFAOYSA-N 49458 (6E)-6-[5-(4-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[5-(4-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[5-(4-methoxyphenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::2-[5-(4-Methoxy-phenyl)-1H-pyrazol-3-yl]-phenol::MLS000551030::SMR000145157::cid_6614449 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49458&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6614449 252629735 ZINC13118859 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239088 COc1ccc2c(C)cc(SCC(=O)c3ccc4OCOc4c3)nc2c1 InChI=1S/C20H17NO4S/c1-12-7-20(21-16-9-14(23-2)4-5-15(12)16)26-10-17(22)13-3-6-18-19(8-13)25-11-24-18/h3-9H,10-11H2,1-2H3 OUJGUHKUZWWVSB-UHFFFAOYSA-N 114843 1-(1,3-benzodioxol-5-yl)-2-(7-methoxy-4-methyl-quinolin-2-yl)sulfanyl-ethanone::1-(1,3-benzodioxol-5-yl)-2-(7-methoxy-4-methylquinolin-2-yl)sulfanylethanone::1-(1,3-benzodioxol-5-yl)-2-[(7-methoxy-4-methyl-2-quinolinyl)thio]ethanone::1-(1,3-benzodioxol-5-yl)-2-[(7-methoxy-4-methyl-2-quinolyl)thio]ethanone::MLS000565124::SMR000152346::cid_1190196 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114843&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1190196 252664313 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239089 Cc1cnc(NC(=O)CCCc2nc3ccccc3s2)s1 InChI=1S/C15H15N3OS2/c1-10-9-16-15(20-10)18-13(19)7-4-8-14-17-11-5-2-3-6-12(11)21-14/h2-3,5-6,9H,4,7-8H2,1H3,(H,16,18,19) MWYJTJSJYKOZSD-UHFFFAOYSA-N 96956 4-(1,3-benzothiazol-2-yl)-N-(5-methyl-1,3-thiazol-2-yl)butanamide::4-(1,3-benzothiazol-2-yl)-N-(5-methyl-2-thiazolyl)butanamide::4-(1,3-benzothiazol-2-yl)-N-(5-methylthiazol-2-yl)butyramide::MLS000568842::SMR000154827::cid_2445782 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96956&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2445782 164038200 ZINC03329769 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239090 OC(=O)C(=O)C(=C/c1ccccc1)\c1ccc2ccccc2n1 InChI=1S/C19H13NO3/c21-18(19(22)23)15(12-13-6-2-1-3-7-13)17-11-10-14-8-4-5-9-16(14)20-17/h1-12H,(H,22,23)/b15-12- GVOXCUPVDMSYQW-QINSGFPZSA-N 114844 (Z)-2-keto-4-phenyl-3-(2-quinolyl)but-3-enoic acid::(Z)-2-oxidanylidene-4-phenyl-3-quinolin-2-yl-but-3-enoic acid::(Z)-2-oxo-4-phenyl-3-(2-quinolinyl)-3-butenoic acid::(Z)-2-oxo-4-phenyl-3-quinolin-2-ylbut-3-enoic acid::MLS000566768::SMR000153680::cid_6223787 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114844&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6223787 252664314 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239091 Clc1ccc2sc(SCC(=O)c3cc4ccccc4o3)nc2c1 InChI=1S/C17H10ClNO2S2/c18-11-5-6-16-12(8-11)19-17(23-16)22-9-13(20)15-7-10-3-1-2-4-14(10)21-15/h1-8H,9H2 OVUKSXMFCJNVRB-UHFFFAOYSA-N 88838 1-(1-benzofuran-2-yl)-2-[(5-chloranyl-1,3-benzothiazol-2-yl)sulfanyl]ethanone::1-(1-benzofuran-2-yl)-2-[(5-chloro-1,3-benzothiazol-2-yl)sulfanyl]ethanone::1-(2-benzofuranyl)-2-[(5-chloro-1,3-benzothiazol-2-yl)thio]ethanone::1-(benzofuran-2-yl)-2-[(5-chloro-1,3-benzothiazol-2-yl)thio]ethanone::MLS000564961::SMR000152211::cid_2361973 Oxysterols receptor LXR-beta 67540 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88838&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2361973 252660459 ZINC03244587 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239092 Cc1ccc(cc1)C(=O)Nc1ccc2OCOc2c1 InChI=1S/C15H13NO3/c1-10-2-4-11(5-3-10)15(17)16-12-6-7-13-14(8-12)19-9-18-13/h2-8H,9H2,1H3,(H,16,17) UOPUHWXWLLBPFB-UHFFFAOYSA-N 114845 MLS000525999::N-(1,3-benzodioxol-5-yl)-4-methyl-benzamide::N-(1,3-benzodioxol-5-yl)-4-methylbenzamide::N-Benzo[1,3]dioxol-5-yl-4-methyl-benzamide::SMR000116473::cid_675179 Oxysterols receptor LXR-beta 67522 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114845&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 675179 252664315 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239093 COc1ccc(Nc2nc(cs2)-c2ccccc2)cc1 InChI=1S/C16H14N2OS/c1-19-14-9-7-13(8-10-14)17-16-18-15(11-20-16)12-5-3-2-4-6-12/h2-11H,1H3,(H,17,18) NAVZSNBQDOGYKD-UHFFFAOYSA-N 49484 (4-methoxyphenyl)-(4-phenylthiazol-2-yl)amine::MLS000565006::N-(4-methoxyphenyl)-4-phenyl-1,3-thiazol-2-amine::N-(4-methoxyphenyl)-4-phenyl-2-thiazolamine::SMR000152166::cid_1548457 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49484&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1548457 252629760 ZINC05526864 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239094 COc1cccc(c1)\N=c1/oc2ccc(OC)cc2cc1-c1nc2ccccc2[nH]1 InChI=1S/C24H19N3O3/c1-28-17-7-5-6-16(14-17)25-24-19(23-26-20-8-3-4-9-21(20)27-23)13-15-12-18(29-2)10-11-22(15)30-24/h3-14H,1-2H3,(H,26,27)/b25-24- BWKCCZSYOZNDJF-IZHYLOQSSA-N 41040 3-(1H-benzimidazol-2-yl)-6-methoxy-N-(3-methoxyphenyl)-1-benzopyran-2-imine::3-(1H-benzimidazol-2-yl)-6-methoxy-N-(3-methoxyphenyl)chromen-2-imine::MLS000325088::N-[3-(1H-benzimidazol-2-yl)-6-methoxy-2H-chromen-2-ylidene]-N-(3-methoxyphenyl)amine::SMR000163989::[3-(1H-benzimidazol-2-yl)-6-methoxy-chromen-2-ylidene]-(3-methoxyphenyl)amine::cid_1212122 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41040&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1212122 252621817 ZINC12944417 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239095 Cc1cc(C)c(C#N)c(SCc2nc3ccccc3[nH]2)n1 InChI=1S/C16H14N4S/c1-10-7-11(2)18-16(12(10)8-17)21-9-15-19-13-5-3-4-6-14(13)20-15/h3-7H,9H2,1-2H3,(H,19,20) WPJVQVKEGZOOOJ-UHFFFAOYSA-N 59276 2-(1H-benzimidazol-2-ylmethylsulfanyl)-4,6-dimethyl-pyridine-3-carbonitrile::2-(1H-benzimidazol-2-ylmethylsulfanyl)-4,6-dimethylpyridine-3-carbonitrile::2-(1H-benzimidazol-2-ylmethylthio)-4,6-dimethyl-3-pyridinecarbonitrile::2-(1H-benzimidazol-2-ylmethylthio)-4,6-dimethyl-nicotinonitrile::2-[(1H-benzimidazol-2-ylmethyl)sulfanyl]-4,6-dimethylnicotinonitrile::MLS000543675::SMR000162925::cid_596156 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=59276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=59276&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 596156 252638916 ZINC02503649 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239096 Cn1cc(Cl)c(n1)C(=O)Nc1nc2ccccc2s1 InChI=1S/C12H9ClN4OS/c1-17-6-7(13)10(16-17)11(18)15-12-14-8-4-2-3-5-9(8)19-12/h2-6H,1H3,(H,14,15,18) HYALETWBHGSDOP-UHFFFAOYSA-N 114734 4-Chloro-1-methyl-1H-pyrazole-3-carboxylic acid benzothiazol-2-ylamide::MLS000560315::N-(1,3-benzothiazol-2-yl)-4-chloranyl-1-methyl-pyrazole-3-carboxamide::N-(1,3-benzothiazol-2-yl)-4-chloro-1-methyl-3-pyrazolecarboxamide::N-(1,3-benzothiazol-2-yl)-4-chloro-1-methyl-pyrazole-3-carboxamide::N-(1,3-benzothiazol-2-yl)-4-chloro-1-methylpyrazole-3-carboxamide::SMR000178022::cid_749848 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114734&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 749848 252664214 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239097 Fc1ccc(cc1)-c1cn2cc(cc(Cl)c2n1)C(F)(F)F InChI=1S/C14H7ClF4N2/c15-11-5-9(14(17,18)19)6-21-7-12(20-13(11)21)8-1-3-10(16)4-2-8/h1-7H LHUTUFIEQFAVFB-UHFFFAOYSA-N 49517 8-chloranyl-2-(4-fluorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine::8-chloro-2-(4-fluorophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine::MLS000547249::SMR000180347::cid_1485610 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49517&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1485610 252629793 ZINC01399532 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239098 C(N=Nc1nc2ccccc2s1)c1cccs1 InChI=1S/C12H9N3S2/c1-2-6-11-10(5-1)14-12(17-11)15-13-8-9-4-3-7-16-9/h1-7H,8H2 MJEQKJODPGHXBV-UHFFFAOYSA-N 49528 1,3-benzothiazol-2-yl-(2-thenylideneamino)amine::1,3-benzothiazol-2-yl-[(E)-2-thenylideneamino]amine::2-thiophenecarbaldehyde 1,3-benzothiazol-2-ylhydrazone::MLS000578792::N-(thiophen-2-ylmethylideneamino)-1,3-benzothiazol-2-amine::SMR000186581::cid_321179 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49528&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896802 252629804 ZINC04582930 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239099 Cc1ccccc1-c1cc(on1)-c1ccccc1O InChI=1S/C16H13NO2/c1-11-6-2-3-7-12(11)14-10-16(19-17-14)13-8-4-5-9-15(13)18/h2-10,18H,1H3 YKNHGENBUSXLPZ-UHFFFAOYSA-N 49531 (6E)-6-[3-(2-methylphenyl)-2H-1,2-oxazol-5-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[3-(2-methylphenyl)-2H-isoxazol-5-ylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[3-(o-tolyl)-3-isoxazolin-5-ylidene]cyclohexa-2,4-dien-1-one::2-[3-(2-methylphenyl)-5-isoxazolyl]phenol::MLS000570875::SMR000193297::cid_11958868 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49531&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11958868 252629807 ZINC15974419 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239100 Oc1ccccc1-c1cc(no1)-c1ccccc1 InChI=1S/C15H11NO2/c17-14-9-5-4-8-12(14)15-10-13(16-18-15)11-6-2-1-3-7-11/h1-10,17H XWLIMTFPYMGWEB-UHFFFAOYSA-N 49532 (6E)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-6-(3-phenyl-2H-1,2-oxazol-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-6-(3-phenyl-2H-isoxazol-5-ylidene)-1-cyclohexa-2,4-dienone::(6Z)-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::2-(3-phenyl-5-isoxazolyl)phenol::MLS000570866::SMR000187290::cid_5343445 Oxysterols receptor LXR-beta 67472 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49532&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5343445 252629808 ZINC13130481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239101 NC(=NOC(=O)c1ccccc1Cl)c1ccccc1 InChI=1S/C14H11ClN2O2/c15-12-9-5-4-8-11(12)14(18)19-17-13(16)10-6-2-1-3-7-10/h1-9H,(H2,16,17) ATXRRRCIHZTEEH-UHFFFAOYSA-N 49546 2-chlorobenzoic acid [(Z)-[amino(phenyl)methylene]amino] ester::2-chlorobenzoic acid [(Z)-[amino(phenyl)methylidene]amino] ester::MLS000576943::N'-[(2-chlorobenzoyl)oxy]benzenecarboximidamide::SMR000185421::[(Z)-[amino(phenyl)methylidene]amino] 2-chlorobenzoate::[(Z)-[azanyl(phenyl)methylidene]amino] 2-chloranylbenzoate::cid_5332683 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49546&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5332683 252629822 ZINC04170067 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239102 C(N=Nc1nc2ccccc2s1)c1ccc2OCOc2c1 InChI=1S/C15H11N3O2S/c1-2-4-14-11(3-1)17-15(21-14)18-16-8-10-5-6-12-13(7-10)20-9-19-12/h1-7H,8-9H2 FLPXBDSAMCYBMJ-UHFFFAOYSA-N 114847 1,3-benzodioxole-5-carbaldehyde 1,3-benzothiazol-2-ylhydrazone::1,3-benzothiazol-2-yl-[(E)-piperonylideneamino]amine::MLS000576981::N-[(E)-1,3-benzodioxol-5-ylmethylideneamino]-1,3-benzothiazol-2-amine::SMR000186009::cid_9561228 Oxysterols receptor LXR-beta 67521 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114847&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91614282 252664316 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239103 Cc1cccc(OCCNC(=O)c2cncc(Br)c2)c1 InChI=1S/C15H15BrN2O2/c1-11-3-2-4-14(7-11)20-6-5-18-15(19)12-8-13(16)10-17-9-12/h2-4,7-10H,5-6H2,1H3,(H,18,19) BKKRVITVWBFKFM-UHFFFAOYSA-N 114848 5-bromanyl-N-[2-(3-methylphenoxy)ethyl]pyridine-3-carboxamide::5-bromo-N-[2-(3-methylphenoxy)ethyl]-3-pyridinecarboxamide::5-bromo-N-[2-(3-methylphenoxy)ethyl]nicotinamide::5-bromo-N-[2-(3-methylphenoxy)ethyl]pyridine-3-carboxamide::MLS000574685::SMR000196113::cid_1825101 Oxysterols receptor LXR-beta 67502 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114848&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1825101 252664317 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239104 c1ccc(cc1)-c1ncc2c(ccc3ccccc23)n1 InChI=1S/C18H12N2/c1-2-7-14(8-3-1)18-19-12-16-15-9-5-4-6-13(15)10-11-17(16)20-18/h1-12H IMSYUORUXGLFGX-UHFFFAOYSA-N 114849 3-phenylbenzo[f]quinazoline::MLS000583364::SMR000184804::cid_781070 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114849&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 781070 252664318 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239105 [O-][N+](=O)c1cc(Cl)ccc1-c1nc(no1)-c1ccccc1 InChI=1S/C14H8ClN3O3/c15-10-6-7-11(12(8-10)18(19)20)14-16-13(17-21-14)9-4-2-1-3-5-9/h1-8H VERLWQQKPGBIIH-UHFFFAOYSA-N 49570 5-(4-chloranyl-2-nitro-phenyl)-3-phenyl-1,2,4-oxadiazole::5-(4-chloro-2-nitro-phenyl)-3-phenyl-1,2,4-oxadiazole::5-(4-chloro-2-nitrophenyl)-3-phenyl-1,2,4-oxadiazole::MLS000578496::SMR000198496::cid_891545 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49570&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 891545 252629846 ZINC00467147 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239106 Cc1ccc(-c2cc(no2)-c2ccccc2)c(O)c1 InChI=1S/C16H13NO2/c1-11-7-8-13(15(18)9-11)16-10-14(17-19-16)12-5-3-2-4-6-12/h2-10,18H,1H3 SROVOMIPMPRXBF-UHFFFAOYSA-N 45062 (6E)-3-methyl-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-3-methyl-6-(3-phenyl-2H-1,2-oxazol-5-ylidene)cyclohexa-2,4-dien-1-one::(6Z)-3-methyl-6-(3-phenyl-2H-isoxazol-5-ylidene)-1-cyclohexa-2,4-dienone::(6Z)-3-methyl-6-(3-phenyl-3-isoxazolin-5-ylidene)cyclohexa-2,4-dien-1-one::5-methyl-2-(3-phenyl-5-isoxazolyl)phenol::MLS000583415::SMR000193314::cid_5414842 Oxysterols receptor LXR-beta 67499 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=45062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=45062&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5414842 252625665 ZINC13126409 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239107 Fc1ccccc1N=CCC(=O)c1cccs1 InChI=1S/C13H10FNOS/c14-10-4-1-2-5-11(10)15-8-7-12(16)13-6-3-9-17-13/h1-6,8-9H,7H2 IFELZHLIAFEBIF-UHFFFAOYSA-N 49573 (E)-3-(2-fluoroanilino)-1-(2-thienyl)prop-2-en-1-one::(E)-3-(2-fluoroanilino)-1-thiophen-2-yl-2-propen-1-one::(E)-3-(2-fluoroanilino)-1-thiophen-2-ylprop-2-en-1-one::(E)-3-[(2-fluorophenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one::3-[(2-fluorophenyl)amino]-1-(2-thienyl)-2-propen-1-one::MLS000581475::SMR000200101::cid_2212375 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49573&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896813 252629849 ZINC02859027 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239108 N#C\C(=C\c1ccco1)c1nc2ccccc2s1 InChI=1S/C14H8N2OS/c15-9-10(8-11-4-3-7-17-11)14-16-12-5-1-2-6-13(12)18-14/h1-8H/b10-8- DBIXCVADFDLNNY-NTMALXAHSA-N 49574 (Z)-2-(1,3-benzothiazol-2-yl)-3-(2-furanyl)-2-propenenitrile::(Z)-2-(1,3-benzothiazol-2-yl)-3-(2-furyl)acrylonitrile::(Z)-2-(1,3-benzothiazol-2-yl)-3-(furan-2-yl)prop-2-enenitrile::(Z)-2-Benzothiazol-2-yl-3-furan-2-yl-acrylonitrile::MLS000589637::SMR000219445::cid_7441600 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49574&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7441600 252629850 ZINC04981697 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239109 Cc1ccc2nsnc2c1NC(=O)c1cccnc1Cl InChI=1S/C13H9ClN4OS/c1-7-4-5-9-11(18-20-17-9)10(7)16-13(19)8-3-2-6-15-12(8)14/h2-6H,1H3,(H,16,19) SEBKFLBPORXNDJ-UHFFFAOYSA-N 114851 2-Chloro-N-(5-methyl-benzo[1,2,5]thiadiazol-4-yl)-nicotinamide::2-chloranyl-N-(5-methyl-2,1,3-benzothiadiazol-4-yl)pyridine-3-carboxamide::2-chloro-N-(5-methyl-2,1,3-benzothiadiazol-4-yl)-3-pyridinecarboxamide::2-chloro-N-(5-methyl-2,1,3-benzothiadiazol-4-yl)pyridine-3-carboxamide::2-chloro-N-(5-methylpiazthiol-4-yl)nicotinamide::MLS000332370::SMR000221658::cid_2038732 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114851&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2038732 252664319 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239110 Cc1c(oc2ccccc12)C(=O)N1CCc2ccccc12 InChI=1S/C18H15NO2/c1-12-14-7-3-5-9-16(14)21-17(12)18(20)19-11-10-13-6-2-4-8-15(13)19/h2-9H,10-11H2,1H3 LOQUVEWCPHKFJK-UHFFFAOYSA-N 49586 1-[(3-methyl-1-benzofuran-2-yl)carbonyl]indoline::2,3-dihydroindol-1-yl-(3-methyl-1-benzofuran-2-yl)methanone::2,3-dihydroindol-1-yl-(3-methyl-2-benzofuranyl)methanone::MLS000583266::SMR000201102::cid_1247770::indolin-1-yl-(3-methylbenzofuran-2-yl)methanone Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49586&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1247770 252629861 ZINC01056660 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239111 O=C1\C(Sc2ccc3ccccc3c12)=C/c1cccs1 InChI=1S/C17H10OS2/c18-17-15(10-12-5-3-9-19-12)20-14-8-7-11-4-1-2-6-13(11)16(14)17/h1-10H/b15-10+ NYRSOTAWRKGABU-XNTDXEJSSA-N 114852 (2E)-2-(2-thenylidene)benzo[e]benzothiophen-1-one::(2E)-2-(thien-2-ylmethylene)naphtho[2,1-b]thiophen-1(2H)-one::(2E)-2-(thiophen-2-ylmethylidene)-1-benzo[e][1]benzothiolone::(2E)-2-(thiophen-2-ylmethylidene)benzo[e][1]benzothiol-1-one::MLS000584663::SMR000203626::cid_12004806 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114852&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 12004806 252664320 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239112 C\C(\C=N\NC(=O)Cn1cnc2ccccc12)=C/c1ccccc1 InChI=1S/C19H18N4O/c1-15(11-16-7-3-2-4-8-16)12-21-22-19(24)13-23-14-20-17-9-5-6-10-18(17)23/h2-12,14H,13H2,1H3,(H,22,24)/b15-11+,21-12+ POAAROIRKSJBID-BLXLCHOJSA-N 114853 2-(1-benzimidazolyl)-N-[(E)-[(E)-2-methyl-3-phenylprop-2-enylidene]amino]acetamide::2-(1H-benzimidazol-1-yl)-N'-[(1E,2E)-2-methyl-3-phenylprop-2-enylidene]acetohydrazide::2-(benzimidazol-1-yl)-N-[(E)-[(E)-2-methyl-3-phenyl-prop-2-enylidene]amino]acetamide::2-(benzimidazol-1-yl)-N-[(E)-[(E)-2-methyl-3-phenyl-prop-2-enylidene]amino]ethanamide::2-(benzimidazol-1-yl)-N-[(E)-[(E)-2-methyl-3-phenylprop-2-enylidene]amino]acetamide::MLS000584770::SMR000203733::cid_6861920 Oxysterols receptor LXR-beta 67509 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114853&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6861920 252664321 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239113 COc1cc(cc(OC)c1OC)-c1nc2ccccc2c(=O)n1N InChI=1S/C17H17N3O4/c1-22-13-8-10(9-14(23-2)15(13)24-3)16-19-12-7-5-4-6-11(12)17(21)20(16)18/h4-9H,18H2,1-3H3 RKYBKQZTIXJELW-UHFFFAOYSA-N 114854 3-amino-2-(3,4,5-trimethoxyphenyl)-4-quinazolinone::3-amino-2-(3,4,5-trimethoxyphenyl)quinazolin-4(3H)-one::3-amino-2-(3,4,5-trimethoxyphenyl)quinazolin-4-one::3-azanyl-2-(3,4,5-trimethoxyphenyl)quinazolin-4-one::MLS000584729::SMR000203692::cid_777426 Oxysterols receptor LXR-beta 67470 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114854&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 777426 252664322 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239114 CCC(C)n1c(=S)[nH]c2c3cc(ccc3sc2c1=O)[N+]([O-])=O InChI=1S/C14H13N3O3S2/c1-3-7(2)16-13(18)12-11(15-14(16)21)9-6-8(17(19)20)4-5-10(9)22-12/h4-7H,3H2,1-2H3,(H,15,21) ITGATILNQMEVOW-UHFFFAOYSA-N 114855 3-butan-2-yl-8-nitro-2-sulfanylidene-1H-[1]benzothiolo[3,2-d]pyrimidin-4-one::3-sec-butyl-8-nitro-2-thioxo-2,3-dihydro[1]benzothieno[3,2-d]pyrimidin-4(1H)-one::8-nitro-3-sec-butyl-2-thioxo-1H-benzothiopheno[3,2-d]pyrimidin-4-one::MLS000583534::SMR000206720::cid_4178152 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114855&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4178152 252664323 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239115 CN(\N=N\c1ccc(cc1)[N+]([O-])=O)c1ccccc1 InChI=1S/C13H12N4O2/c1-16(12-5-3-2-4-6-12)15-14-11-7-9-13(10-8-11)17(18)19/h2-10H,1H3/b15-14+ ALCSAJMCUCMDLJ-CCEZHUSRSA-N 51011 (1E)-3-methyl-1-(4-nitrophenyl)-3-phenyltriaz-1-ene::MLS000584152::N-methyl-N-(4-nitrophenyl)azoaniline::N-methyl-N-[(4-nitrophenyl)diazenyl]aniline::SMR000203315::cid_4562252::methyl-(4-nitrophenyl)azo-phenyl-amine Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4562252 252631251 ZINC13136468 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239116 Cc1ccsc1CN=Nc1nc2ccccc2s1 InChI=1S/C13H11N3S2/c1-9-6-7-17-12(9)8-14-16-13-15-10-4-2-3-5-11(10)18-13/h2-7H,8H2,1H3 HWYBRHKYOVZRQM-UHFFFAOYSA-N 49600 1,3-benzothiazol-2-yl-[(3-methyl-2-thienyl)methyleneamino]amine::1,3-benzothiazol-2-yl-[(E)-(3-methyl-2-thienyl)methyleneamino]amine::3-methylthiophene-2-carbaldehyde 1,3-benzothiazol-2-ylhydrazone::MLS000583439::N-[(3-methyl-2-thiophenyl)methylideneamino]-1,3-benzothiazol-2-amine::N-[(3-methylthiophen-2-yl)methylideneamino]-1,3-benzothiazol-2-amine::SMR000206625::cid_388816 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49600&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896816 252629875 ZINC13137086 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239117 CCOc1ccc(NC(=O)Cc2cccc3ccccc23)c(c1)[N+]([O-])=O InChI=1S/C20H18N2O4/c1-2-26-16-10-11-18(19(13-16)22(24)25)21-20(23)12-15-8-5-7-14-6-3-4-9-17(14)15/h3-11,13H,2,12H2,1H3,(H,21,23) FARDPLTYIZYBOS-UHFFFAOYSA-N 114857 MLS000584283::N-(4-ethoxy-2-nitro-phenyl)-2-(1-naphthyl)acetamide::N-(4-ethoxy-2-nitro-phenyl)-2-naphthalen-1-yl-ethanamide::N-(4-ethoxy-2-nitrophenyl)-2-(1-naphthalenyl)acetamide::N-(4-ethoxy-2-nitrophenyl)-2-(1-naphthyl)acetamide::N-(4-ethoxy-2-nitrophenyl)-2-naphthalen-1-ylacetamide::SMR000203446::cid_3928077 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114857&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3928077 252664324 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239118 CCOC(=O)C(=C\c1cn(CCOc2ccccc2)c2ccccc12)\C#N InChI=1S/C22H20N2O3/c1-2-26-22(25)17(15-23)14-18-16-24(21-11-7-6-10-20(18)21)12-13-27-19-8-4-3-5-9-19/h3-11,14,16H,2,12-13H2,1H3/b17-14+ QVRSRKDDGRYCFK-SAPNQHFASA-N 114858 (E)-2-cyano-3-[1-(2-phenoxyethyl)-3-indolyl]-2-propenoic acid ethyl ester::(E)-2-cyano-3-[1-(2-phenoxyethyl)indol-3-yl]acrylic acid ethyl ester::MLS000585070::SMR000203833::cid_6186137::ethyl (2E)-2-cyano-3-[1-(2-phenoxyethyl)-1H-indol-3-yl]acrylate::ethyl (E)-2-cyano-3-[1-(2-phenoxyethyl)indol-3-yl]prop-2-enoate Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114858&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6186137 252664325 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239119 Cc1cc2nc([nH]c2cc1C)-c1ccc(SCc2ccc(cc2)C(O)=O)nc1 InChI=1S/C22H19N3O2S/c1-13-9-18-19(10-14(13)2)25-21(24-18)17-7-8-20(23-11-17)28-12-15-3-5-16(6-4-15)22(26)27/h3-11H,12H2,1-2H3,(H,24,25)(H,26,27) LUOLJCHANBCQCP-UHFFFAOYSA-N 50422 4-[[5-(5,6-dimethyl-1H-benzimidazol-2-yl)pyridin-2-yl]sulfanylmethyl]benzoic acid::4-[[[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridinyl]thio]methyl]benzoic acid::4-[[[5-(5,6-dimethyl-1H-benzimidazol-2-yl)-2-pyridyl]thio]methyl]benzoic acid::MLS000715853::SMR000277370::cid_1432813 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1432813 252630683 ZINC37867873 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239120 Oc1cc2ccccc2c2C(C(C#N)C(=N)Oc12)c1ccsc1 InChI=1S/C18H12N2O2S/c19-8-13-15(11-5-6-23-9-11)16-12-4-2-1-3-10(12)7-14(21)17(16)22-18(13)20/h1-7,9,13,15,20-21H PRGLHLMBGDQDEC-UHFFFAOYSA-N 72223 3-amino-5-hydroxy-1-(3-thienyl)-1H-benzo[f]chromene-2-carbonitrile::3-amino-5-hydroxy-1-(3-thiophenyl)-1H-benzo[f][1]benzopyran-2-carbonitrile::3-amino-5-hydroxy-1-thiophen-3-yl-1H-benzo[f]chromene-2-carbonitrile::3-azanyl-5-oxidanyl-1-thiophen-3-yl-1H-benzo[f]chromene-2-carbonitrile::MLS000587525::SMR000211589::cid_3333046 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72223&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91898016 252649486 ZINC00497156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239121 Fc1ccccc1-c1ccc(CN=Nc2nc3ccccc3[nH]2)o1 InChI=1S/C18H13FN4O/c19-14-6-2-1-5-13(14)17-10-9-12(24-17)11-20-23-18-21-15-7-3-4-8-16(15)22-18/h1-10H,11H2,(H,21,22) LMAYLOZMYMCWIB-UHFFFAOYSA-N 114859 1H-benzimidazol-2-yl-[(E)-[5-(2-fluorophenyl)-2-furyl]methyleneamino]amine::MLS000332159::N-(1H-Benzoimidazol-2-yl)-N'-[1-[5-(2-fluoro-phenyl)-furan-2-yl]-meth-(E)-ylidene]-hydrazine::N-[(E)-[5-(2-fluorophenyl)-2-furanyl]methylideneamino]-1H-benzimidazol-2-amine::N-[(E)-[5-(2-fluorophenyl)furan-2-yl]methylideneamino]-1H-benzimidazol-2-amine::SMR000221570::cid_9638453 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114859&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899738 252664326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239123 CC1CCC(CC1)NC(=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C15H21NO3S/c1-11-3-7-13(8-4-11)16-15(17)12-5-9-14(10-6-12)20(2,18)19/h5-6,9-11,13H,3-4,7-8H2,1-2H3,(H,16,17) ORMVZDWFBZDCNW-UHFFFAOYSA-N 114860 4-mesyl-N-(4-methylcyclohexyl)benzamide::MLS000334252::N-(4-methylcyclohexyl)-4-methylsulfonyl-benzamide::N-(4-methylcyclohexyl)-4-methylsulfonylbenzamide::SMR000249010::cid_2456765 Oxysterols receptor LXR-beta 67514 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114860&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2456765 252664327 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239124 NC1=NC(=NNc2nc(cs2)-c2ccc(F)cc2)c2ccccc12 InChI=1S/C17H12FN5S/c18-11-7-5-10(6-8-11)14-9-24-17(20-14)23-22-16-13-4-2-1-3-12(13)15(19)21-16/h1-9H,(H,20,23)(H2,19,21,22) NJWXVZWFKPLZJI-UHFFFAOYSA-N 42059 MLS000391275::N-[(Z)-(3-amino-1-isoindolylidene)amino]-4-(4-fluorophenyl)-2-thiazolamine::N-[(Z)-(3-aminoisoindol-1-ylidene)amino]-4-(4-fluorophenyl)-1,3-thiazol-2-amine::N-[(Z)-(3-azanylisoindol-1-ylidene)amino]-4-(4-fluorophenyl)-1,3-thiazol-2-amine::SMR000260312::[(Z)-(3-aminoisoindol-1-ylidene)amino]-[4-(4-fluorophenyl)thiazol-2-yl]amine::cid_6261459 Oxysterols receptor LXR-beta 67504 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42059&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6261459 252622774 ZINC08774416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239125 CC(OC(=O)Cn1nc(C)c(c1C)[N+]([O-])=O)C(=O)Nc1ccccc1[N+]([O-])=O InChI=1S/C16H17N5O7/c1-9-15(21(26)27)10(2)19(18-9)8-14(22)28-11(3)16(23)17-12-6-4-5-7-13(12)20(24)25/h4-7,11H,8H2,1-3H3,(H,17,23) KZPVCLLDODLPBZ-UHFFFAOYSA-N 114861 2-(3,5-dimethyl-4-nitro-1-pyrazolyl)acetic acid [1-(2-nitroanilino)-1-oxopropan-2-yl] ester::2-(3,5-dimethyl-4-nitro-pyrazol-1-yl)acetic acid [2-keto-1-methyl-2-(2-nitroanilino)ethyl] ester::MLS000334135::SMR000248893::[1-(2-nitroanilino)-1-oxopropan-2-yl] 2-(3,5-dimethyl-4-nitropyrazol-1-yl)acetate::[1-[(2-nitrophenyl)amino]-1-oxidanylidene-propan-2-yl] 2-(3,5-dimethyl-4-nitro-pyrazol-1-yl)ethanoate::cid_3891741 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114861&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3891741 252664328 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239126 Cc1cc(ccc1\C=C/[N+]([O-])=O)N1CCOCC1 InChI=1S/C13H16N2O3/c1-11-10-13(14-6-8-18-9-7-14)3-2-12(11)4-5-15(16)17/h2-5,10H,6-9H2,1H3/b5-4- CWWALEMHFPAAPJ-PLNGDYQASA-N 79545 4-(4-{2-nitrovinyl}-3-methylphenyl)morpholine::4-[3-methyl-4-[(Z)-2-nitroethenyl]phenyl]morpholine::4-[3-methyl-4-[(Z)-2-nitrovinyl]phenyl]morpholine::MLS000702659::SMR000226523::cid_1782673 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79545&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1782673 252656193 ZINC04457206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239127 CCOc1ccccc1C(=O)N[C@@H](C(C)C)C(=O)Nc1nc2CCCCc2s1 InChI=1S/C21H27N3O3S/c1-4-27-16-11-7-5-9-14(16)19(25)23-18(13(2)3)20(26)24-21-22-15-10-6-8-12-17(15)28-21/h5,7,9,11,13,18H,4,6,8,10,12H2,1-3H3,(H,23,25)(H,22,24,26)/t18-/m0/s1 DIIXNGDAGALFHX-SFHVURJKSA-N 114862 2-ethoxy-N-[(1S)-2-methyl-1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylcarbamoyl)propyl]benzamide::2-ethoxy-N-[(2S)-3-methyl-1-oxidanylidene-1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylamino)butan-2-yl]benzamide::2-ethoxy-N-[(2S)-3-methyl-1-oxo-1-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylamino)butan-2-yl]benzamide::MLS000334403::SMR000249161::cid_7838220 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114862&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7838220 252664329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239128 FC(F)(F)c1cc(NC(=O)CCNC(=O)c2ccccc2Cl)ccc1Br InChI=1S/C17H13BrClF3N2O2/c18-13-6-5-10(9-12(13)17(20,21)22)24-15(25)7-8-23-16(26)11-3-1-2-4-14(11)19/h1-6,9H,7-8H2,(H,23,26)(H,24,25) SCFUXYGOTDGMAV-UHFFFAOYSA-N 114863 MLS000334398::N-[3-[4-bromo-3-(trifluoromethyl)anilino]-3-keto-propyl]-2-chloro-benzamide::N-[3-[4-bromo-3-(trifluoromethyl)anilino]-3-oxopropyl]-2-chlorobenzamide::N-[3-[[4-bromanyl-3-(trifluoromethyl)phenyl]amino]-3-oxidanylidene-propyl]-2-chloranyl-benzamide::SMR000249156::cid_2481997 Oxysterols receptor LXR-beta 67502 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114863&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2481997 252664330 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239129 CCCCN(C(=O)CSc1cc(C)c2ccc(OC)cc2n1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O InChI=1S/C28H31N5O4S/c1-4-5-13-32(25-26(29)33(28(36)31-27(25)35)16-19-9-7-6-8-10-19)24(34)17-38-23-14-18(2)21-12-11-20(37-3)15-22(21)30-23/h6-12,14-15H,4-5,13,16-17,29H2,1-3H3,(H,31,35,36) LRQQWHHJRMQEOO-UHFFFAOYSA-N 114864 MLS000334394::N-(6-amino-1-benzyl-2,4-diketo-pyrimidin-5-yl)-N-butyl-2-[(7-methoxy-4-methyl-2-quinolyl)thio]acetamide::N-(6-amino-1-benzyl-2,4-dioxopyrimidin-5-yl)-N-butyl-2-(7-methoxy-4-methylquinolin-2-yl)sulfanylacetamide::N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-N-butyl-2-[(7-methoxy-4-methyl-2-quinolinyl)thio]acetamide::N-[6-azanyl-2,4-bis(oxidanylidene)-1-(phenylmethyl)pyrimidin-5-yl]-N-butyl-2-(7-methoxy-4-methyl-quinolin-2-yl)sulfanyl-ethanamide::SMR000249152::cid_2483322 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114864&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2483322 252664331 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239131 FC(F)(F)c1ccc2nnn(OCC(=O)Nc3c(Cl)cccc3Cl)c2c1 InChI=1S/C15H9Cl2F3N4O2/c16-9-2-1-3-10(17)14(9)21-13(25)7-26-24-12-6-8(15(18,19)20)4-5-11(12)22-23-24/h1-6H,7H2,(H,21,25) CCUVHKGWZHIHRZ-UHFFFAOYSA-N 114865 MLS000335227::N-(2,6-dichlorophenyl)-2-[6-(trifluoromethyl)benzotriazol-1-yl]oxy-acetamide::N-(2,6-dichlorophenyl)-2-[6-(trifluoromethyl)benzotriazol-1-yl]oxyacetamide::N-(2,6-dichlorophenyl)-2-[[6-(trifluoromethyl)-1-benzotriazolyl]oxy]acetamide::N-[2,6-bis(chloranyl)phenyl]-2-[6-(trifluoromethyl)benzotriazol-1-yl]oxy-ethanamide::SMR000249985::cid_2092066 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114865&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2092066 252664332 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239132 Cc1c(oc2ccccc12)C(=O)Nc1nc2ccccc2[nH]1 InChI=1S/C17H13N3O2/c1-10-11-6-2-5-9-14(11)22-15(10)16(21)20-17-18-12-7-3-4-8-13(12)19-17/h2-9H,1H3,(H2,18,19,20,21) TYDFMELDUQFLME-UHFFFAOYSA-N 49662 MLS000335562::N-(1H-benzimidazol-2-yl)-3-methyl-1-benzofuran-2-carboxamide::N-(1H-benzimidazol-2-yl)-3-methyl-2-benzofurancarboxamide::N-(1H-benzimidazol-2-yl)-3-methyl-coumarilamide::SMR000253316::cid_2117785 Oxysterols receptor LXR-beta 67516 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49662&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2117785 252629937 ZINC12508027 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239133 Cc1nn(Cc2ccccc2)c(Cl)c1\C=N\NC(=O)c1cccnc1 InChI=1S/C18H16ClN5O/c1-13-16(11-21-22-18(25)15-8-5-9-20-10-15)17(19)24(23-13)12-14-6-3-2-4-7-14/h2-11H,12H2,1H3,(H,22,25)/b21-11+ OGNUYRYEVRQURT-SRZZPIQSSA-N 114866 MLS000334799::N-[(E)-(1-benzyl-5-chloro-3-methyl-pyrazol-4-yl)methyleneamino]nicotinamide::N-[(E)-(1-benzyl-5-chloro-3-methylpyrazol-4-yl)methylideneamino]pyridine-3-carboxamide::N-[(E)-[5-chloranyl-3-methyl-1-(phenylmethyl)pyrazol-4-yl]methylideneamino]pyridine-3-carboxamide::N-[(E)-[5-chloro-3-methyl-1-(phenylmethyl)-4-pyrazolyl]methylideneamino]-3-pyridinecarboxamide::SMR000249557::cid_6905913 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114866&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6905913 252664333 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239134 CCCn1nc(C(=O)Nc2ccc3nc(C)sc3c2)c2ccccc2c1=O InChI=1S/C20H18N4O2S/c1-3-10-24-20(26)15-7-5-4-6-14(15)18(23-24)19(25)22-13-8-9-16-17(11-13)27-12(2)21-16/h4-9,11H,3,10H2,1-2H3,(H,22,25) RTCVJYQAXQBCEU-UHFFFAOYSA-N 52497 4-keto-N-(2-methyl-1,3-benzothiazol-6-yl)-3-propyl-phthalazine-1-carboxamide::MLS000335041::N-(2-methyl-1,3-benzothiazol-6-yl)-4-oxidanylidene-3-propyl-phthalazine-1-carboxamide::N-(2-methyl-1,3-benzothiazol-6-yl)-4-oxo-3-propyl-1-phthalazinecarboxamide::N-(2-methyl-1,3-benzothiazol-6-yl)-4-oxo-3-propylphthalazine-1-carboxamide::SMR000249799::cid_2097240 Oxysterols receptor LXR-beta 67540 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52497&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2097240 252632637 ZINC02984190 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239135 COc1ccc(OCc2nnc(SCn3nnc4ccccc4c3=O)n2CC=C)cc1 InChI=1S/C21H20N6O3S/c1-3-12-26-19(13-30-16-10-8-15(29-2)9-11-16)23-24-21(26)31-14-27-20(28)17-6-4-5-7-18(17)22-25-27/h3-11H,1,12-14H2,2H3 NLJUTIUXBXRSBO-UHFFFAOYSA-N 114867 3-[[5-[(4-methoxyphenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1,2,3-benzotriazin-4-one::3-[[[4-allyl-5-[(4-methoxyphenoxy)methyl]-1,2,4-triazol-3-yl]thio]methyl]-1,2,3-benzotriazin-4-one::3-[[[5-[(4-methoxyphenoxy)methyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]methyl]-1,2,3-benzotriazin-4-one::MLS000389251::SMR000255524::cid_2529037 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114867&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2529037 252664334 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239136 CC1CCc2sc(cc2C1)C(=O)NNC(=S)Nc1cccc(C)c1C InChI=1S/C19H23N3OS2/c1-11-7-8-16-14(9-11)10-17(25-16)18(23)21-22-19(24)20-15-6-4-5-12(2)13(15)3/h4-6,10-11H,7-9H2,1-3H3,(H,21,23)(H2,20,22,24) CDAPYQPMGBZKAR-UHFFFAOYSA-N 65220 1-(2,3-dimethylphenyl)-3-[(5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)carbonylamino]thiourea::1-(2,3-dimethylphenyl)-3-[(5-methyl-4,5,6,7-tetrahydro-1-benzothiophene-2-carbonyl)amino]thiourea::1-(2,3-dimethylphenyl)-3-[(5-methyl-4,5,6,7-tetrahydrobenzothiophene-2-carbonyl)amino]thiourea::1-(2,3-dimethylphenyl)-3-[[(5-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-oxomethyl]amino]thiourea::MLS000334286::SMR000249044::cid_4830778 Oxysterols receptor LXR-beta 67524 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65220&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4830778 252643958 ZINC08685022 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239137 N(N=Cc1ccccc1)C1=Nc2cccc3cccc1c23 InChI=1S/C18H13N3/c1-2-6-13(7-3-1)12-19-21-18-15-10-4-8-14-9-5-11-16(20-18)17(14)15/h1-12H,(H,20,21) BHVRGHUCIOBZDB-UHFFFAOYSA-N 51101 (benzalamino)-benzo[cd]indol-2-yl-amine::MLS000392783::N-(benzylideneamino)benzo[cd]indol-2-amine::N-[(phenylmethylene)amino]-2-benzo[cd]indolamine::N-[(phenylmethylidene)amino]benzo[cd]indol-2-amine::SMR000261715::[(E)-benzalamino]-benzo[cd]indol-2-yl-amine::cid_2315076 Oxysterols receptor LXR-beta 67540 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51101&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6899626 252631337 ZINC06440858 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239138 Cc1cnc(NC(=O)c2sc3ccccc3c2Cl)s1 InChI=1S/C13H9ClN2OS2/c1-7-6-15-13(18-7)16-12(17)11-10(14)8-4-2-3-5-9(8)19-11/h2-6H,1H3,(H,15,16,17) PETQNGKAFAHVEX-UHFFFAOYSA-N 76503 3-chloranyl-N-(5-methyl-1,3-thiazol-2-yl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methyl-1,3-thiazol-2-yl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methyl-2-thiazolyl)-1-benzothiophene-2-carboxamide::3-chloro-N-(5-methylthiazol-2-yl)benzothiophene-2-carboxamide::MLS000334487::SMR000249245::cid_2523343 Oxysterols receptor LXR-beta 67507 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76503&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2523343 252653681 ZINC03404622 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239139 Cc1ccc(CN=Nc2ccc(Cl)c(c2)C(O)=O)s1 InChI=1S/C13H11ClN2O2S/c1-8-2-4-10(19-8)7-15-16-9-3-5-12(14)11(6-9)13(17)18/h2-6H,7H2,1H3,(H,17,18) JYKSMVJKAVBAGF-UHFFFAOYSA-N 49674 2-chloranyl-5-[2-[(5-methylthiophen-2-yl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[(N''E)-N''-[(5-methyl-2-thienyl)methylene]hydrazino]benzoic acid::2-chloro-5-[(N'E)-N'-[(5-methyl-2-thienyl)methylene]hydrazino]benzoic acid::2-chloro-5-[2-[(5-methyl-2-thiophenyl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[2-[(5-methylthiophen-2-yl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[N'-[(5-methyl-2-thienyl)methylene]hydrazino]benzoic acid::MLS000336758::SMR000244073::cid_3669063 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49674&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896827 252629949 ZINC13143549 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239140 Cc1ccc2N=C(CC(C)=Nc2c1)c1ccccc1 InChI=1S/C17H16N2/c1-12-8-9-15-17(10-12)18-13(2)11-16(19-15)14-6-4-3-5-7-14/h3-10H,11H2,1-2H3 SYYPSJCHWJCPGU-UHFFFAOYSA-N 114869 2,8-dimethyl-4-phenyl-1H-1,5-benzodiazepine::4,7-dimethyl-2-phenyl-1H-1,5-benzodiazepine::MLS000699849::SMR000226316::cid_768630 Oxysterols receptor LXR-beta 67485 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114869&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899739 252664335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239141 CC(=O)NC(=S)Nc1ccccc1C(=O)NC1CCCCC1 InChI=1S/C16H21N3O2S/c1-11(20)17-16(22)19-14-10-6-5-9-13(14)15(21)18-12-7-3-2-4-8-12/h5-6,9-10,12H,2-4,7-8H2,1H3,(H,18,21)(H2,17,19,20,22) PURGNTBPZPRXAE-UHFFFAOYSA-N 114870 2-(acetylcarbamothioylamino)-N-cyclohexylbenzamide::2-(acetylthiocarbamoylamino)-N-cyclohexyl-benzamide::2-[[acetamido(sulfanylidene)methyl]amino]-N-cyclohexylbenzamide::2-{[(acetylamino)carbothioyl]amino}-N-cyclohexylbenzamide::MLS000701772::N-cyclohexyl-2-(ethanoylcarbamothioylamino)benzamide::SMR000228830::cid_1226733 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114870&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1226733 252664336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239142 O=C(Nc1ccccc1)c1nc2ccccc2s1 InChI=1S/C14H10N2OS/c17-13(15-10-6-2-1-3-7-10)14-16-11-8-4-5-9-12(11)18-14/h1-9H,(H,15,17) YBBITEUFVRDJFO-UHFFFAOYSA-N 49698 MLS000703113::N-phenyl-1,3-benzothiazole-2-carboxamide::SMR000226557::cid_900706 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49698&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 900706 252629973 ZINC00479753 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239143 O=C(CSc1nc2n[nH]cc2c(=O)[nH]1)Nc1nccs1 InChI=1S/C10H8N6O2S2/c17-6(13-9-11-1-2-19-9)4-20-10-14-7-5(3-12-16-7)8(18)15-10/h1-3H,4H2,(H,11,13,17)(H2,12,14,15,16,18) HVPONRJUCLDLFY-UHFFFAOYSA-N 114871 2-[(4-keto-1,2-dihydropyrazolo[3,4-d]pyrimidin-6-yl)thio]-N-thiazol-2-yl-acetamide::2-[(4-oxidanylidene-1,2-dihydropyrazolo[3,4-d]pyrimidin-6-yl)sulfanyl]-N-(1,3-thiazol-2-yl)ethanamide::2-[(4-oxo-1,2-dihydropyrazolo[3,4-d]pyrimidin-6-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide::2-[(4-oxo-1,2-dihydropyrazolo[3,4-d]pyrimidin-6-yl)thio]-N-(2-thiazolyl)acetamide::MLS000684956::SMR000324911::cid_7151614 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114871&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7151614 252664337 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239144 CCN(CC)CCn1nc2-c3ccccc3-c3cccc(c23)c1=O InChI=1S/C20H21N3O/c1-3-22(4-2)12-13-23-20(24)17-11-7-10-15-14-8-5-6-9-16(14)19(21-23)18(15)17/h5-11H,3-4,12-13H2,1-2H3 XNRPWZMOVUAHLY-UHFFFAOYSA-N 72391 2-[2-(diethylamino)ethyl]indeno[1,2,3-de]phthalazin-3(2H)-one::MLS000676185::SMR000271925::cid_2052803 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72391&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2052803 242053547 ZINC02459149 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239145 CC1=NN(C(=O)CCc2ccc3OCOc3c2)C(O)(C1)C(F)(F)F InChI=1S/C15H15F3N2O4/c1-9-7-14(22,15(16,17)18)20(19-9)13(21)5-3-10-2-4-11-12(6-10)24-8-23-11/h2,4,6,22H,3,5,7-8H2,1H3 KAARXXHMFMEOLE-UHFFFAOYSA-N 69092 3-(1,3-benzodioxol-5-yl)-1-[3-methyl-5-oxidanyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]propan-1-one::3-(1,3-benzodioxol-5-yl)-1-[5-hydroxy-3-methyl-5-(trifluoromethyl)-2-pyrazolin-1-yl]propan-1-one::3-(1,3-benzodioxol-5-yl)-1-[5-hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-1-propanone::3-(1,3-benzodioxol-5-yl)-1-[5-hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]propan-1-one::MLS000709012::SMR000289779::cid_3157872 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69092&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3157872 252647263 ZINC00814205 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239146 Oc1ccccc1C=Cc1noc(n1)-c1ccccc1O InChI=1S/C16H12N2O3/c19-13-7-3-1-5-11(13)9-10-15-17-16(21-18-15)12-6-2-4-8-14(12)20/h1-10,19-20H OUGQQERBJUGIMD-UHFFFAOYSA-N 76519 (6E)-6-[(2E)-2-[(5Z)-5-(6-ketocyclohexa-2,4-dien-1-ylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[(2E)-2-[(5Z)-5-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[(2E)-2-[(5Z)-5-(6-oxo-1-cyclohexa-2,4-dienylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[(2E)-2-[(5Z)-5-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2,4-oxadiazolidin-3-ylidene]ethylidene]cyclohexa-2,4-dien-1-one::2-{2-[5-(2-hydroxyphenyl)-1,2,4-oxadiazol-3-yl]vinyl}phenol::MLS000626734::SMR000299118::cid_16188892 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76519&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16188892 252653697 ZINC04171743 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239147 Nc1cc2nn(nc2cc1Cl)-c1ccccc1 InChI=1S/C12H9ClN4/c13-9-6-11-12(7-10(9)14)16-17(15-11)8-4-2-1-3-5-8/h1-7H,14H2 VQJOWEVCMNYOEK-UHFFFAOYSA-N 34853 (6-chloro-2-phenyl-benzotriazol-5-yl)amine::6-chloranyl-2-phenyl-benzotriazol-5-amine::6-chloro-2-phenyl-5-benzotriazolamine::6-chloro-2-phenylbenzotriazol-5-amine::MLS000706165::SMR000288217::cid_736374 Oxysterols receptor LXR-beta 67537 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34853&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 736374 252617499 ZINC00157516 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239148 Nc1nonc1OCCCCOc1nonc1N InChI=1S/C8H12N6O4/c9-5-7(13-17-11-5)15-3-1-2-4-16-8-6(10)12-18-14-8/h1-4H2,(H2,9,11)(H2,10,12) PAYYMOBPWIAJPK-UHFFFAOYSA-N 114872 4-[4-[(4-amino-1,2,5-oxadiazol-3-yl)oxy]butoxy]-1,2,5-oxadiazol-3-amine::4-[4-[(4-azanyl-1,2,5-oxadiazol-3-yl)oxy]butoxy]-1,2,5-oxadiazol-3-amine::4-{4-[(4-amino-1,2,5-oxadiazol-3-yl)oxy]butoxy}-1,2,5-oxadiazol-3-ylamine::MLS000702155::SMR000226095::[4-[4-(4-aminofurazan-3-yl)oxybutoxy]furazan-3-yl]amine::cid_1720465 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114872&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1720465 252664338 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239149 FC(F)(F)c1ccc(Oc2ccc(Cl)cc2Br)nc1 InChI=1S/C12H6BrClF3NO/c13-9-5-8(14)2-3-10(9)19-11-4-1-7(6-18-11)12(15,16)17/h1-6H VVEINCRMDZUXCG-UHFFFAOYSA-N 114873 2-(2-bromanyl-4-chloranyl-phenoxy)-5-(trifluoromethyl)pyridine::2-(2-bromo-4-chloro-phenoxy)-5-(trifluoromethyl)pyridine::2-(2-bromo-4-chlorophenoxy)-5-(trifluoromethyl)pyridine::MLS000662349::SMR000292875::cid_1313785 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114873&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1313785 252664339 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239150 CCNC1=NN=C(CS1)c1c[nH]c2ccccc12 InChI=1S/C13H14N4S/c1-2-14-13-17-16-12(8-18-13)10-7-15-11-6-4-3-5-9(10)11/h3-7,15H,2,8H2,1H3,(H,14,17) RTVWFRWPDMGZSQ-UHFFFAOYSA-N 114874 (5E)-N-ethyl-5-(3-indolylidene)-4H-1,3,4-thiadiazin-2-amine::(5E)-N-ethyl-5-indol-3-ylidene-4H-1,3,4-thiadiazin-2-amine::MLS000335162::SMR000249920::cid_5818829::ethyl-[(5E)-5-indol-3-ylidene-4H-1,3,4-thiadiazin-2-yl]amine Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114874&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5818829 252664340 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239151 Cc1cc(NC(=S)NC(=O)C=Cc2ccc(cc2)S(=O)(=O)N2CCOCC2)ccc1Br InChI=1S/C21H22BrN3O4S2/c1-15-14-17(5-8-19(15)22)23-21(30)24-20(26)9-4-16-2-6-18(7-3-16)31(27,28)25-10-12-29-13-11-25/h2-9,14H,10-13H2,1H3,(H2,23,24,26,30) OLNNQWPGUSFGCB-UHFFFAOYSA-N 114875 (E)-N-[(4-bromanyl-3-methyl-phenyl)carbamothioyl]-3-(4-morpholin-4-ylsulfonylphenyl)prop-2-enamide::(E)-N-[(4-bromo-3-methyl-phenyl)thiocarbamoyl]-3-(4-morpholinosulfonylphenyl)acrylamide::(E)-N-[(4-bromo-3-methylanilino)-sulfanylidenemethyl]-3-[4-(4-morpholinylsulfonyl)phenyl]-2-propenamide::(E)-N-[(4-bromo-3-methylphenyl)carbamothioyl]-3-(4-morpholin-4-ylsulfonylphenyl)prop-2-enamide::MLS000402284::SMR000243009::cid_2421488 Oxysterols receptor LXR-beta 67524 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114875&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2421488 252664341 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239152 COc1ccc(Nc2nc(N)nc(CSC(=S)N3CCN(C)CC3)n2)cc1 InChI=1S/C17H23N7OS2/c1-23-7-9-24(10-8-23)17(26)27-11-14-20-15(18)22-16(21-14)19-12-3-5-13(25-2)6-4-12/h3-6H,7-11H2,1-2H3,(H3,18,19,20,21,22) GVWXNYLUBSUZET-UHFFFAOYSA-N 114876 4-methyl-1-piperazinecarbodithioic acid [4-amino-6-(4-methoxyanilino)-1,3,5-triazin-2-yl]methyl ester::4-methylpiperazine-1-carbodithioic acid [4-amino-6-(p-anisidino)-s-triazin-2-yl]methyl ester::MLS000677505::SMR000271673::[4-amino-6-(4-methoxyanilino)-1,3,5-triazin-2-yl]methyl 4-methylpiperazine-1-carbodithioate::[4-azanyl-6-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl]methyl 4-methylpiperazine-1-carbodithioate::cid_1576927::{4-amino-6-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}methyl 4-methyl-1-piperazinecarbodithioate Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114876&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1576927 252664342 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239153 CC(=O)Nc1ccc(cc1)-n1c(O)cc(Sc2nc3ccccc3s2)c1O InChI=1S/C19H15N3O3S2/c1-11(23)20-12-6-8-13(9-7-12)22-17(24)10-16(18(22)25)27-19-21-14-4-2-3-5-15(14)26-19/h2-10,24-25H,1H3,(H,20,23) BXBYQLRXNWNOBK-UHFFFAOYSA-N 114877 MLS000677492::N-[4-[3-(1,3-benzothiazol-2-ylsulfanyl)-2,5-bis(oxidanylidene)pyrrolidin-1-yl]phenyl]ethanamide::N-[4-[3-(1,3-benzothiazol-2-ylsulfanyl)-2,5-dioxopyrrolidin-1-yl]phenyl]acetamide::N-[4-[3-(1,3-benzothiazol-2-ylthio)-2,5-diketo-pyrrolidino]phenyl]acetamide::N-[4-[3-(1,3-benzothiazol-2-ylthio)-2,5-dioxo-1-pyrrolidinyl]phenyl]acetamide::N-{4-[3-(1,3-benzothiazol-2-ylthio)-2,5-dioxo-1-pyrrolidinyl]phenyl}acetamide::SMR000271668::cid_2927301 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114877&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899740 252664343 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239154 FC(F)(F)c1ccccc1NC(=O)CCN1C(=O)C2C3CCC(C3)C2C1=O InChI=1S/C19H19F3N2O3/c20-19(21,22)12-3-1-2-4-13(12)23-14(25)7-8-24-17(26)15-10-5-6-11(9-10)16(15)18(24)27/h1-4,10-11,15-16H,5-9H2,(H,23,25) HIMOTPAEFIRMHB-UHFFFAOYSA-N 114878 3-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-4-yl)-N-[2-(trifluoromethyl)phenyl]propanamide::MLS000677612::SMR000271548::cid_2925597 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114878&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2925597 242053907 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239155 O=C(Nc1ccc2OCOc2c1)Nc1ccc2OCCOc2c1 InChI=1S/C16H14N2O5/c19-16(18-11-2-4-13-15(8-11)23-9-22-13)17-10-1-3-12-14(7-10)21-6-5-20-12/h1-4,7-8H,5-6,9H2,(H2,17,18,19) XEOBUSLELWJDNO-UHFFFAOYSA-N 49777 1-(1,3-benzodioxol-5-yl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)urea::MLS000679554::N-1,3-benzodioxol-5-yl-N'-(2,3-dihydro-1,4-benzodioxin-6-yl)urea::SMR000297821::cid_6470323 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49777&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6470323 252630052 ZINC06741794 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239156 [O-][N+](=O)c1ccc(cc1)C(=O)CCNc1ccc(Cc2ccncc2)cc1 InChI=1S/C21H19N3O3/c25-21(18-3-7-20(8-4-18)24(26)27)11-14-23-19-5-1-16(2-6-19)15-17-9-12-22-13-10-17/h1-10,12-13,23H,11,14-15H2 AXUSWWVSARYCQT-UHFFFAOYSA-N 34875 1-(4-nitrophenyl)-3-[4-(4-pyridylmethyl)anilino]propan-1-one::1-(4-nitrophenyl)-3-[4-(pyridin-4-ylmethyl)anilino]-1-propanone::1-(4-nitrophenyl)-3-[4-(pyridin-4-ylmethyl)anilino]propan-1-one::1-(4-nitrophenyl)-3-[[4-(pyridin-4-ylmethyl)phenyl]amino]propan-1-one::1-(4-nitrophenyl)-3-{[4-(4-pyridinylmethyl)phenyl]amino}-1-propanone::MLS000663673::SMR000292952::cid_1287136 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34875&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1287136 252617520 ZINC01108293 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239157 COc1cccc(c1)-c1nc(no1)-c1cccs1 InChI=1S/C13H10N2O2S/c1-16-10-5-2-4-9(8-10)13-14-12(15-17-13)11-6-3-7-18-11/h2-8H,1H3 YCPYSZXBSIVBQG-UHFFFAOYSA-N 114748 5-(3-methoxyphenyl)-3-(2-thienyl)-1,2,4-oxadiazole::5-(3-methoxyphenyl)-3-thiophen-2-yl-1,2,4-oxadiazole::MLS000674346::SMR000297310::cid_718728 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114748&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 718728 252664227 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239158 NC(=NOC(=O)c1cc(Br)ccc1Cl)c1ccccn1 InChI=1S/C13H9BrClN3O2/c14-8-4-5-10(15)9(7-8)13(19)20-18-12(16)11-3-1-2-6-17-11/h1-7H,(H2,16,18) CGXGAXMMGDPJML-UHFFFAOYSA-N 49794 5-bromo-2-chloro-benzoic acid [(Z)-[amino(2-pyridyl)methylene]amino] ester::5-bromo-2-chlorobenzoic acid [(Z)-[amino(2-pyridinyl)methylidene]amino] ester::MLS000625126::N'-[(5-bromo-2-chlorobenzoyl)oxy]-2-pyridinecarboximidamide::SMR000293913::[(Z)-[amino(pyridin-2-yl)methylidene]amino] 5-bromo-2-chlorobenzoate::[(Z)-[azanyl(pyridin-2-yl)methylidene]amino] 5-bromanyl-2-chloranyl-benzoate::cid_9587775 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49794&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9587775 252630069 ZINC05059847 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239159 COc1ccc(cc1)C1CC(=NN1C(=O)CN1CCCCC1)c1cccs1 InChI=1S/C21H25N3O2S/c1-26-17-9-7-16(8-10-17)19-14-18(20-6-5-13-27-20)22-24(19)21(25)15-23-11-3-2-4-12-23/h5-10,13,19H,2-4,11-12,14-15H2,1H3 UEFCNZQFBKWAOH-UHFFFAOYSA-N 114879 1-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-(1-piperidinyl)ethanone::1-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-piperidin-1-yl-ethanone::1-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-piperidin-1-ylethanone::1-[5-(4-methoxyphenyl)-3-(2-thienyl)-2-pyrazolin-1-yl]-2-piperidino-ethanone::1-{2-[5-(4-methoxyphenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazol-1-yl]-2-oxoethyl}piperidine::MLS000625091::SMR000293877::cid_2953411 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114879&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2953411 252664344 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239160 COC(=O)c1ccccc1NC(=O)c1ccnn1C InChI=1S/C13H13N3O3/c1-16-11(7-8-14-16)12(17)15-10-6-4-3-5-9(10)13(18)19-2/h3-8H,1-2H3,(H,15,17) MKVVJWRRLDTYJC-UHFFFAOYSA-N 114880 2-[(2-methylpyrazole-3-carbonyl)amino]benzoic acid methyl ester::2-[[(2-methyl-3-pyrazolyl)-oxomethyl]amino]benzoic acid methyl ester::MLS000679455::SMR000297602::cid_6466448::methyl 2-[(2-methylpyrazol-3-yl)carbonylamino]benzoate::methyl 2-[(2-methylpyrazole-3-carbonyl)amino]benzoate::methyl 2-{[(1-methyl-1H-pyrazol-5-yl)carbonyl]amino}benzoate Oxysterols receptor LXR-beta 67480 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114880&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6466448 252664345 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239161 CCn1c(C)cc(C=C2C(=O)c3ccccc3C2=O)c1C InChI=1S/C18H17NO2/c1-4-19-11(2)9-13(12(19)3)10-16-17(20)14-7-5-6-8-15(14)18(16)21/h5-10H,4H2,1-3H3 UMIPDSYINQNGJY-UHFFFAOYSA-N 51158 2-[(1-ethyl-2,5-dimethyl-1H-pyrrol-3-yl)methylene]-1H-indene-1,3(2H)-dione::2-[(1-ethyl-2,5-dimethyl-3-pyrrolyl)methylidene]indene-1,3-dione::2-[(1-ethyl-2,5-dimethyl-pyrrol-3-yl)methylene]indane-1,3-quinone::2-[(1-ethyl-2,5-dimethyl-pyrrol-3-yl)methylidene]indene-1,3-dione::2-[(1-ethyl-2,5-dimethylpyrrol-3-yl)methylidene]indene-1,3-dione::MLS000675733::SMR000292102::cid_848081 Oxysterols receptor LXR-beta 67522 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51158&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 848081 252631392 ZINC00382329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239162 COC(=O)c1ccccc1NC(=O)NCc1ccncc1 InChI=1S/C15H15N3O3/c1-21-14(19)12-4-2-3-5-13(12)18-15(20)17-10-11-6-8-16-9-7-11/h2-9H,10H2,1H3,(H2,17,18,20) BYLIKNRZYGMQES-UHFFFAOYSA-N 73602 2-(4-pyridylmethylcarbamoylamino)benzoic acid methyl ester::2-[[oxo-(pyridin-4-ylmethylamino)methyl]amino]benzoic acid methyl ester::MLS000679358::SMR000297760::cid_6469219::methyl 2-(pyridin-4-ylmethylcarbamoylamino)benzoate::methyl 2-({[(4-pyridinylmethyl)amino]carbonyl}amino)benzoate Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73602&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6469219 252650842 ZINC06715529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239163 COc1ccc(NC(=O)NC(C)C2CC3CCC2C3)cc1 InChI=1S/C17H24N2O2/c1-11(16-10-12-3-4-13(16)9-12)18-17(20)19-14-5-7-15(21-2)8-6-14/h5-8,11-13,16H,3-4,9-10H2,1-2H3,(H2,18,19,20) WWVGSAHKMLYXBR-UHFFFAOYSA-N 114881 1-(4-methoxyphenyl)-3-[1-(2-norbornyl)ethyl]urea::1-[1-(3-bicyclo[2.2.1]heptanyl)ethyl]-3-(4-methoxyphenyl)urea::MLS000679477::N-(1-bicyclo[2.2.1]hept-2-ylethyl)-N'-(4-methoxyphenyl)urea::SMR000297627::cid_6466832 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114881&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6466832 252664346 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239164 Cc1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)nc1 InChI=1S/C14H12F3N3O/c1-9-5-6-12(18-8-9)20-13(21)19-11-4-2-3-10(7-11)14(15,16)17/h2-8H,1H3,(H2,18,19,20,21) RQTWKJRZIHKQIX-UHFFFAOYSA-N 114882 1-(5-methyl-2-pyridinyl)-3-[3-(trifluoromethyl)phenyl]urea::1-(5-methyl-2-pyridyl)-3-[3-(trifluoromethyl)phenyl]urea::1-(5-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]urea::MLS000679414::N-(5-methyl-2-pyridinyl)-N'-[3-(trifluoromethyl)phenyl]urea::SMR000297575::cid_4454820 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114882&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4454820 252664347 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239165 CC(N(C)C(=O)CCc1nnc(Cc2c[nH]c3ccccc23)o1)c1nccs1 InChI=1S/C20H21N5O2S/c1-13(20-21-9-10-28-20)25(2)19(26)8-7-17-23-24-18(27-17)11-14-12-22-16-6-4-3-5-15(14)16/h3-6,9-10,12-13,22H,7-8,11H2,1-2H3 APDKMWRQIPKGIP-UHFFFAOYSA-N 114883 3-[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-(1-thiazol-2-ylethyl)propionamide::3-[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-[1-(1,3-thiazol-2-yl)ethyl]propanamide::3-[5-(1H-indol-3-ylmethyl)-1,3,4-oxadiazol-2-yl]-N-methyl-N-[1-(2-thiazolyl)ethyl]propanamide::MLS000732963::SMR000316080::cid_16189916 Oxysterols receptor LXR-beta 67522 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114883&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16189916 252664348 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239166 Oc1cccc(CN=Nc2cccc3cccnc23)c1 InChI=1S/C16H13N3O/c20-14-7-1-4-12(10-14)11-18-19-15-8-2-5-13-6-3-9-17-16(13)15/h1-10,20H,11H2 ZNYHMSCZUCMHEP-UHFFFAOYSA-N 49805 3-[(8-quinolinylhydrazinylidene)methyl]phenol::3-[(8-quinolylhydrazono)methyl]phenol::3-[(E)-(8-quinolylhydrazono)methyl]phenol::3-[(quinolin-8-ylhydrazinylidene)methyl]phenol::MLS000713447::SMR000272928::cid_2856025 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49805&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896849 252630080 ZINC33398799 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239167 Cc1ccc(cc1)-c1cc2nc(C)cc(C)n2n1 InChI=1S/C15H15N3/c1-10-4-6-13(7-5-10)14-9-15-16-11(2)8-12(3)18(15)17-14/h4-9H,1-3H3 UVVMCIKINUABHH-UHFFFAOYSA-N 114750 5,7-dimethyl-2-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine::5,7-dimethyl-2-(p-tolyl)pyrazolo[1,5-a]pyrimidine::MLS000711692::SMR000281459::cid_761947 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 761947 252664228 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239168 COc1cccc(-c2nc3ccccc3s2)c1O InChI=1S/C14H11NO2S/c1-17-11-7-4-5-9(13(11)16)14-15-10-6-2-3-8-12(10)18-14/h2-8,16H,1H3 CKFLKUKQCSXXBI-UHFFFAOYSA-N 114884 (6Z)-6-(3H-1,3-benzothiazol-2-ylidene)-2-methoxy-1-cyclohexa-2,4-dienone::(6Z)-6-(3H-1,3-benzothiazol-2-ylidene)-2-methoxy-cyclohexa-2,4-dien-1-one::(6Z)-6-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,4-dien-1-one::MLS000716124::SMR000277641::cid_5439163 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114884&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5439163 252664349 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239169 Clc1ccc(cc1)C(=O)COC(=O)CNC(=O)c1cccs1 InChI=1S/C15H12ClNO4S/c16-11-5-3-10(4-6-11)12(18)9-21-14(19)8-17-15(20)13-2-1-7-22-13/h1-7H,8-9H2,(H,17,20) GUZYVFGDWODQCT-UHFFFAOYSA-N 114885 2-(2-thenoylamino)acetic acid [2-(4-chlorophenyl)-2-keto-ethyl] ester::2-[[oxo(thiophen-2-yl)methyl]amino]acetic acid [2-(4-chlorophenyl)-2-oxoethyl] ester::MLS000765410::SMR000289515::[2-(4-chlorophenyl)-2-oxidanylidene-ethyl] 2-(thiophen-2-ylcarbonylamino)ethanoate::[2-(4-chlorophenyl)-2-oxoethyl] 2-(thiophene-2-carbonylamino)acetate::cid_3158562 Oxysterols receptor LXR-beta 67520 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114885&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3158562 252664350 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239170 CC(=O)c1ccc2C(=O)N(CCc3ccccc3)C(=O)c3cccc1c23 InChI=1S/C22H17NO3/c1-14(24)16-10-11-19-20-17(16)8-5-9-18(20)21(25)23(22(19)26)13-12-15-6-3-2-4-7-15/h2-11H,12-13H2,1H3 IYQGUSRVQQAKLP-UHFFFAOYSA-N 96684 6-acetyl-2-(2-phenylethyl)benzo[de]isoquinoline-1,3-dione::6-acetyl-2-phenethyl-benzo[de]isoquinoline-1,3-quinone::6-ethanoyl-2-(2-phenylethyl)benzo[de]isoquinoline-1,3-dione::MLS000765478::SMR000289583::cid_2929978 Oxysterols receptor LXR-beta 67502 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96684&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2929978 164037928 ZINC04546360 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239171 Cc1cc(C)n2nc(cc2n1)-c1ccccc1 InChI=1S/C14H13N3/c1-10-8-11(2)17-14(15-10)9-13(16-17)12-6-4-3-5-7-12/h3-9H,1-2H3 AZWWKRAUFGDLEV-UHFFFAOYSA-N 114886 5,7-dimethyl-2-phenyl-pyrazolo[1,5-a]pyrimidine::5,7-dimethyl-2-phenylpyrazolo[1,5-a]pyrimidine::MLS000711401::SMR000281168::cid_737207 Oxysterols receptor LXR-beta 67479 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114886&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 737207 252664351 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239172 COc1cc(CC=C)ccc1OCCCCOc1ccc(cc1)C(O)=O InChI=1S/C21H24O5/c1-3-6-16-7-12-19(20(15-16)24-2)26-14-5-4-13-25-18-10-8-17(9-11-18)21(22)23/h3,7-12,15H,1,4-6,13-14H2,2H3,(H,22,23) CLLBNUPLAROHBC-UHFFFAOYSA-N 114887 4-[4-(2-methoxy-4-prop-2-enyl-phenoxy)butoxy]benzoic acid::4-[4-(2-methoxy-4-prop-2-enylphenoxy)butoxy]benzoic acid::4-[4-(4-allyl-2-methoxy-phenoxy)butoxy]benzoic acid::4-[4-(4-allyl-2-methoxyphenoxy)butoxy]benzoic acid::MLS000676599::SMR000298473::cid_2292109 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114887&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2292109 252664352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239173 CCc1ccc(cc1)-c1csc2ncn(CC)c(=O)c12 InChI=1S/C16H16N2OS/c1-3-11-5-7-12(8-6-11)13-9-20-15-14(13)16(19)18(4-2)10-17-15/h5-10H,3-4H2,1-2H3 YIWTWHWBWIVRHO-UHFFFAOYSA-N 114888 3-ethyl-5-(4-ethylphenyl)-4-thieno[2,3-d]pyrimidinone::3-ethyl-5-(4-ethylphenyl)thieno[2,3-d]pyrimidin-4-one::MLS000708897::SMR000289664::cid_724924 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114888&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 724924 252664353 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239174 Oc1cccc(c1)-c1nc2cc(ccc2o1)[N+]([O-])=O InChI=1S/C13H8N2O4/c16-10-3-1-2-8(6-10)13-14-11-7-9(15(17)18)4-5-12(11)19-13/h1-7,16H UCTFKBGKVAFVLT-UHFFFAOYSA-N 114751 3-(5-nitro-1,3-benzoxazol-2-yl)phenol::MLS000715569::SMR000275548::cid_1160269 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1160269 252664229 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239175 Cc1ccc(cc1)C1(C)NC(=O)N(CC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)C1=O InChI=1S/C20H19N5O4/c1-11-3-5-12(6-4-11)20(2)17(27)25(19(29)24-20)10-16(26)21-13-7-8-14-15(9-13)23-18(28)22-14/h3-9H,10H2,1-2H3,(H,21,26)(H,24,29)(H2,22,23,28) DTPVIDNSXOFSNE-UHFFFAOYSA-N 50615 2-[2,5-diketo-4-methyl-4-(p-tolyl)imidazolidin-1-yl]-N-(2-keto-1,3-dihydrobenzimidazol-5-yl)acetamide::2-[4-methyl-4-(4-methylphenyl)-2,5-bis(oxidanylidene)imidazolidin-1-yl]-N-(2-oxidanylidene-1,3-dihydrobenzimidazol-5-yl)ethanamide::2-[4-methyl-4-(4-methylphenyl)-2,5-dioxo-1-imidazolidinyl]-N-(2-oxo-1,3-dihydrobenzimidazol-5-yl)acetamide::2-[4-methyl-4-(4-methylphenyl)-2,5-dioxoimidazolidin-1-yl]-N-(2-oxo-1,3-dihydrobenzimidazol-5-yl)acetamide::MLS000761299::SMR000369605::cid_3876612 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50615&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3876612 252630873 ZINC13124329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239176 Cc1ccc(cc1)-c1cn2cccc(C)c2n1 InChI=1S/C15H14N2/c1-11-5-7-13(8-6-11)14-10-17-9-3-4-12(2)15(17)16-14/h3-10H,1-2H3 BBWDULJOEGZFPY-UHFFFAOYSA-N 49825 8-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine::8-methyl-2-(p-tolyl)imidazo[1,2-a]pyridine::MLS000718734::SMR000291002::cid_696182 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49825&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 696182 252630100 ZINC00071130 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239177 CC(=O)NC1(CCN(CC1)c1cc(C)nc(n1)-c1ccccc1)c1ccccc1 InChI=1S/C24H26N4O/c1-18-17-22(26-23(25-18)20-9-5-3-6-10-20)28-15-13-24(14-16-28,27-19(2)29)21-11-7-4-8-12-21/h3-12,17H,13-16H2,1-2H3,(H,27,29) WFJXDLYYEDRZLL-UHFFFAOYSA-N 114889 MLS000708623::N-[1-(6-methyl-2-phenyl-4-pyrimidinyl)-4-phenyl-4-piperidinyl]acetamide::N-[1-(6-methyl-2-phenyl-pyrimidin-4-yl)-4-phenyl-4-piperidyl]acetamide::N-[1-(6-methyl-2-phenyl-pyrimidin-4-yl)-4-phenyl-piperidin-4-yl]ethanamide::N-[1-(6-methyl-2-phenylpyrimidin-4-yl)-4-phenylpiperidin-4-yl]acetamide::SMR000289190::cid_1448074 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114889&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1448074 252664354 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239178 O=C(NCC1CCCO1)C(=C\c1ccc(o1)N1CCOCC1)\C#N InChI=1S/C17H21N3O4/c18-11-13(17(21)19-12-15-2-1-7-23-15)10-14-3-4-16(24-14)20-5-8-22-9-6-20/h3-4,10,15H,1-2,5-9,12H2,(H,19,21)/b13-10+ JLNNUDJPLDUYQM-JLHYYAGUSA-N 75818 (E)-2-cyano-3-(5-morpholin-4-ylfuran-2-yl)-N-(oxolan-2-ylmethyl)prop-2-enamide::(E)-2-cyano-3-(5-morpholino-2-furyl)-N-(tetrahydrofurfuryl)acrylamide::(E)-2-cyano-3-[5-(4-morpholinyl)-2-furanyl]-N-(2-oxolanylmethyl)-2-propenamide::MLS000687813::SMR000284872::cid_5344735 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=75818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=75818&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5344735 252653014 ZINC00247484 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239179 CNCC(O)Cn1c2CCCCc2c2ccccc12 InChI=1S/C16H22N2O/c1-17-10-12(19)11-18-15-8-4-2-6-13(15)14-7-3-5-9-16(14)18/h2,4,6,8,12,17,19H,3,5,7,9-11H2,1H3 FMMHNMZYUSRVGE-UHFFFAOYSA-N 114890 1-(methylamino)-3-(1,2,3,4-tetrahydrocarbazol-9-yl)-2-propanol::1-(methylamino)-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-2-ol::MLS000709188::SMR000289855::cid_3159022 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114890&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3159022 252664355 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239180 Cc1ccccc1C(=O)N\N=C1\SCC(=O)N1Cc1ccccc1 InChI=1S/C18H17N3O2S/c1-13-7-5-6-10-15(13)17(23)19-20-18-21(16(22)12-24-18)11-14-8-3-2-4-9-14/h2-10H,11-12H2,1H3,(H,19,23)/b20-18+ RKQDESWSWMOKRU-CZIZESTLSA-N 114891 2-methyl-N-[(E)-[4-oxidanylidene-3-(phenylmethyl)-1,3-thiazolidin-2-ylidene]amino]benzamide::2-methyl-N-[(E)-[4-oxo-3-(phenylmethyl)-2-thiazolidinylidene]amino]benzamide::MLS000687132::N-[(E)-(3-benzyl-4-keto-thiazolidin-2-ylidene)amino]-2-methyl-benzamide::N-[(E)-(3-benzyl-4-oxo-1,3-thiazolidin-2-ylidene)amino]-2-methylbenzamide::SMR000284165::cid_6860195 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114891&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6860195 252664356 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239181 Clc1ccccc1Cn1nnc(n1)-c1ccccc1 InChI=1S/C14H11ClN4/c15-13-9-5-4-8-12(13)10-19-17-14(16-18-19)11-6-2-1-3-7-11/h1-9H,10H2 KFNSNOICAWYJOS-UHFFFAOYSA-N 114892 2-(2-chlorobenzyl)-5-phenyl-tetrazole::2-[(2-chlorophenyl)methyl]-5-phenyl-1,2,3,4-tetrazole::2-[(2-chlorophenyl)methyl]-5-phenyltetrazole::MLS000687399::SMR000285011::cid_856079 Oxysterols receptor LXR-beta 67486 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114892&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 856079 252664357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239182 CCCCCCC1(C)NN(C(=S)N1)c1ccccc1 InChI=1S/C15H23N3S/c1-3-4-5-9-12-15(2)16-14(19)18(17-15)13-10-7-6-8-11-13/h6-8,10-11,17H,3-5,9,12H2,1-2H3,(H,16,19) SICFWIJQWWRONM-UHFFFAOYSA-N 73660 5-hexyl-5-methyl-2-phenyl-1,2,4-triazolidine-3-thione::MLS000711608::SMR000281375::cid_3104627 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73660&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3104627 252650900 ZINC03058573 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239183 CN(\N=C\c1cccnc1)c1cnc2ccccc2n1 InChI=1S/C15H13N5/c1-20(18-10-12-5-4-8-16-9-12)15-11-17-13-6-2-3-7-14(13)19-15/h2-11H,1H3/b18-10+ XDCSSXMPPBUTQH-VCHYOVAHSA-N 114893 MLS000660830::N-methyl-N-[(E)-3-pyridinylmethylideneamino]-2-quinoxalinamine::N-methyl-N-[(E)-pyridin-3-ylmethylideneamino]quinoxalin-2-amine::SMR000310468::cid_9627575::methyl-[(E)-3-pyridylmethyleneamino]-quinoxalin-2-yl-amine::nicotinaldehyde methyl(quinoxalin-2-yl)hydrazone Oxysterols receptor LXR-beta 67486 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114893&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9627575 252664358 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239184 COc1ccc(cc1)C(=O)c1ccccc1 InChI=1S/C14H12O2/c1-16-13-9-7-12(8-10-13)14(15)11-5-3-2-4-6-11/h2-10H,1H3 SWFHGTMLYIBPPA-UHFFFAOYSA-N 50174205 4-methoxybenzophenone::CHEMBL198085::cid_69146 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174205&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 69146 104060027 CHEMBL198085 ZINC00244531 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239185 COc1ccc(CN=Nc2nc3ccccc3s2)cc1O InChI=1S/C15H13N3O2S/c1-20-13-7-6-10(8-12(13)19)9-16-18-15-17-11-4-2-3-5-14(11)21-15/h2-8,19H,9H2,1H3 BACKPBBCSJQNDG-UHFFFAOYSA-N 114894 3-hydroxy-4-methoxybenzaldehyde 1,3-benzothiazol-2-ylhydrazone::5-[(E)-(1,3-benzothiazol-2-ylhydrazinylidene)methyl]-2-methoxy-phenol::5-[(E)-(1,3-benzothiazol-2-ylhydrazinylidene)methyl]-2-methoxyphenol::5-[(E)-(1,3-benzothiazol-2-ylhydrazono)methyl]-2-methoxy-phenol::MLS000673297::SMR000314538::cid_9642984 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114894&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899741 252664359 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239186 Cn1c2ccccc2s\c1=N/C(=O)c1ccco1 InChI=1S/C13H10N2O2S/c1-15-9-5-2-3-7-11(9)18-13(15)14-12(16)10-6-4-8-17-10/h2-8H,1H3/b14-13- LMIMVAOOGHDALO-YPKPFQOOSA-N 114895 MLS000420257::N-(3-methyl-1,3-benzothiazol-2-ylidene)-2-furamide::N-(3-methyl-1,3-benzothiazol-2-ylidene)-2-furancarboxamide::N-(3-methyl-1,3-benzothiazol-2-ylidene)furan-2-carboxamide::SMR000322810::cid_958964 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114895&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 958964 252664360 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239187 COc1ccc(CSc2nnc3[nH]c(=O)cc(N)n23)cc1 InChI=1S/C13H13N5O2S/c1-20-9-4-2-8(3-5-9)7-21-13-17-16-12-15-11(19)6-10(14)18(12)13/h2-6H,7,14H2,1H3,(H,15,16,19) UTZXATYRXOOHMM-UHFFFAOYSA-N 114896 5-amino-3-(p-anisylthio)-1H-[1,2,4]triazolo[4,3-a]pyrimidin-7-one::5-amino-3-[(4-methoxyphenyl)methylsulfanyl]-1H-[1,2,4]triazolo[4,3-a]pyrimidin-7-one::5-amino-3-[(4-methoxyphenyl)methylthio]-1H-[1,2,4]triazolo[4,3-a]pyrimidin-7-one::5-azanyl-3-[(4-methoxyphenyl)methylsulfanyl]-1H-[1,2,4]triazolo[4,3-a]pyrimidin-7-one::MLS000715893::SMR000277410::cid_1819998 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114896&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1819998 252664361 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239188 O=C(CCn1c2ccccc2oc1=S)NC1CCCCC1 InChI=1S/C16H20N2O2S/c19-15(17-12-6-2-1-3-7-12)10-11-18-13-8-4-5-9-14(13)20-16(18)21/h4-5,8-9,12H,1-3,6-7,10-11H2,(H,17,19) MRQLHOZXZYTOQL-UHFFFAOYSA-N 114897 MLS000686698::N-cyclohexyl-3-(2-sulfanylidene-1,3-benzoxazol-3-yl)propanamide::N-cyclohexyl-3-(2-thioxo-1,3-benzoxazol-3(2H)-yl)propanamide::N-cyclohexyl-3-(2-thioxo-1,3-benzoxazol-3-yl)propionamide::SMR000339791::cid_3596457 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114897&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3596457 252664362 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239189 Fc1ccc(cc1)-c1cnn2c(ccnc12)-c1cccs1 InChI=1S/C16H10FN3S/c17-12-5-3-11(4-6-12)13-10-19-20-14(7-8-18-16(13)20)15-2-1-9-21-15/h1-10H HCCADCGJTAFYPW-UHFFFAOYSA-N 49917 3-(4-fluorophenyl)-7-(2-thienyl)pyrazolo[1,5-a]pyrimidine::3-(4-fluorophenyl)-7-thiophen-2-yl-pyrazolo[1,5-a]pyrimidine::3-(4-fluorophenyl)-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine::MLS000721461::SMR000337098::cid_1472857 Oxysterols receptor LXR-beta 67493 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49917&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1472857 252630191 ZINC01384300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239190 CC(N=Nc1cccc2cccnc12)c1ccccc1O InChI=1S/C17H15N3O/c1-12(14-8-2-3-10-16(14)21)19-20-15-9-4-6-13-7-5-11-18-17(13)15/h2-12,21H,1H3 XPNYSLWURLUYQK-UHFFFAOYSA-N 49918 (6E)-6-[1-(2-quinolin-8-ylhydrazinyl)ethylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[1-(8-quinolinylhydrazo)ethylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[1-[N'-(8-quinolyl)hydrazino]ethylidene]cyclohexa-2,4-dien-1-one::1-(2-hydroxyphenyl)-1-ethanone N-(8-quinolinyl)hydrazone::MLS000755258::SMR000338132::cid_5915839 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49918&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896861 252630192 ZINC37868932 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239191 Fc1ccccc1CN=Nc1ncnc2ccccc12 InChI=1S/C15H11FN4/c16-13-7-3-1-5-11(13)9-19-20-15-12-6-2-4-8-14(12)17-10-18-15/h1-8,10H,9H2 KQQNEUJXPKVOEP-UHFFFAOYSA-N 49922 2-fluorobenzenecarbaldehyde N-(4-quinazolinyl)hydrazone::MLS000696288::N-[(2-fluorophenyl)methylideneamino]-4-quinazolinamine::N-[(2-fluorophenyl)methylideneamino]quinazolin-4-amine::SMR000333399::[(2-fluorobenzylidene)amino]-quinazolin-4-yl-amine::[(E)-(2-fluorobenzylidene)amino]-quinazolin-4-yl-amine::cid_3744533 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49922&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896862 252630196 ZINC33935731 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239192 O=c1[nH][nH]cc1C=Nc1ccc(Oc2ccccc2)cc1 InChI=1S/C16H13N3O2/c20-16-12(11-18-19-16)10-17-13-6-8-15(9-7-13)21-14-4-2-1-3-5-14/h1-11H,(H2,18,19,20) PTRDZIYXELODOO-UHFFFAOYSA-N 114899 (4E)-4-[(4-phenoxyanilino)methylene]-2-pyrazolin-3-one::(4E)-4-[(4-phenoxyanilino)methylidene]-1H-pyrazol-5-one::(4E)-4-[[(4-phenoxyphenyl)amino]methylidene]-1H-pyrazol-5-one::4-[(4-phenoxyanilino)methylene]-2,4-dihydro-3H-pyrazol-3-one::MLS000755973::SMR000337648::cid_5525045 Oxysterols receptor LXR-beta 67494 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114899&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5525045 252664363 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239193 CC1CN(CC(C)O1)C1c2c(OC1(C)C)c(ccc2C)[N+]([O-])=O InChI=1S/C17H24N2O4/c1-10-6-7-13(19(20)21)15-14(10)16(17(4,5)23-15)18-8-11(2)22-12(3)9-18/h6-7,11-12,16H,8-9H2,1-5H3 KXNOTNFTDYFDHS-UHFFFAOYSA-N 114900 2,6-dimethyl-4-(2,2,4-trimethyl-7-nitro-2,3-dihydro-1-benzofuran-3-yl)morpholine::2,6-dimethyl-4-(2,2,4-trimethyl-7-nitro-3H-1-benzofuran-3-yl)morpholine::2,6-dimethyl-4-(2,2,4-trimethyl-7-nitro-3H-benzofuran-3-yl)morpholine::2,6-dimethyl-4-(2,2,4-trimethyl-7-nitro-coumaran-3-yl)morpholine::MLS000755642::SMR000337313::cid_5164615 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114900&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5164615 252664364 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239194 OC(=O)c1cccc(c1)N1C(=O)c2ccc(cc2C1=O)C(=O)c1cccc(c1)[N+]([O-])=O InChI=1S/C22H12N2O7/c25-19(12-3-1-6-16(9-12)24(30)31)13-7-8-17-18(11-13)21(27)23(20(17)26)15-5-2-4-14(10-15)22(28)29/h1-11H,(H,28,29) QBZQMQFNHMJFRY-UHFFFAOYSA-N 114901 3-[1,3-diketo-5-(3-nitrobenzoyl)isoindolin-2-yl]benzoic acid::3-[5-(3-nitrobenzoyl)-1,3-dioxoisoindol-2-yl]benzoic acid::3-[5-(3-nitrophenyl)carbonyl-1,3-bis(oxidanylidene)isoindol-2-yl]benzoic acid::3-[5-[(3-nitrophenyl)-oxomethyl]-1,3-dioxo-2-isoindolyl]benzoic acid::MLS000714436::SMR000274415::cid_3091522 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114901&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3091522 252664365 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239195 O=C(CCNC(=O)c1ccccc1)NNC1=c2ccccc2=NC1=O InChI=1S/C18H16N4O3/c23-15(10-11-19-17(24)12-6-2-1-3-7-12)21-22-16-13-8-4-5-9-14(13)20-18(16)25/h1-9H,10-11H2,(H,19,24)(H,21,23)(H,20,22,25) ZKNCDXQHYRYFIR-UHFFFAOYSA-N 114902 MLS000685462::N-[3-keto-3-[N'-(2-ketoindol-3-yl)hydrazino]propyl]benzamide::N-[3-oxidanylidene-3-[2-(2-oxidanylideneindol-3-yl)hydrazinyl]propyl]benzamide::N-[3-oxo-3-[(2-oxo-3-indolyl)hydrazo]propyl]benzamide::N-[3-oxo-3-[2-(2-oxoindol-3-yl)hydrazinyl]propyl]benzamide::N-{3-oxo-3-[(2E)-2-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino]propyl}benzamide::SMR000312426::cid_6244032 Oxysterols receptor LXR-beta 67470 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114902&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6244032 252664366 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239196 NC(=NN=Cc1cccc(O)c1)c1nonc1N InChI=1S/C10H10N6O2/c11-9(8-10(12)16-18-15-8)14-13-5-6-2-1-3-7(17)4-6/h1-5,17H,(H2,11,14)(H2,12,16) QCVAKZIXZJYURU-UHFFFAOYSA-N 49930 4-amino-N'-[(1E)-(3-hydroxyphenyl)methylene]-1,2,5-oxadiazole-3-carbohydrazonamide::4-amino-N''-[(3-hydroxyphenyl)methylideneamino]-1,2,5-oxadiazole-3-carboximidamide::4-amino-N''-[(E)-(3-hydroxybenzylidene)amino]furazan-3-carboxamidine::4-amino-N'-[(3-hydroxybenzylidene)amino]furazan-3-carboxamidine::4-amino-N'-[(E)-(3-hydroxybenzylidene)amino]furazan-3-carboxamidine::4-azanyl-N''-[(3-hydroxyphenyl)methylideneamino]-1,2,5-oxadiazole-3-carboximidamide::MLS000686415::SMR000313258::cid_2202913 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49930&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5338638 252630204 ZINC58984328 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239197 Cc1ccc(NC(=O)C2CC(=O)Nc3nncn23)cc1 InChI=1S/C13H13N5O2/c1-8-2-4-9(5-3-8)15-12(20)10-6-11(19)16-13-17-14-7-18(10)13/h2-5,7,10H,6H2,1H3,(H,15,20)(H,16,17,19) KSYPNTQQWJUKCB-UHFFFAOYSA-N 114904 7-keto-N-(p-tolyl)-5,6-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::MLS000681581::N-(4-methylphenyl)-7-oxidanylidene-5,6-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::N-(4-methylphenyl)-7-oxo-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::N-(4-methylphenyl)-7-oxo-5,6-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine-5-carboxamide::SMR000312258::cid_5294610 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114904&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5294610 252664367 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239199 FC(F)(F)c1cccc(c1)-n1nc2c(cc1=O)[nH][nH]c2=O InChI=1S/C12H5F3N4O2/c13-12(14,15)6-2-1-3-7(4-6)19-9(20)5-8-10(18-19)11(21)17-16-8/h1-5H SOCOLQMGCDZAOD-UHFFFAOYSA-N 72583 3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1,5-dihydro-6H-pyrazolo[4,3-c]pyridazin-6-one::5-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrazolo[4,3-c]pyridazine-3,6-dione::5-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrazolo[4,3-c]pyridazine-3,6-quinone::MLS000755378::SMR000337772::cid_1478561 Oxysterols receptor LXR-beta 67484 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72583&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1478561 252649841 ZINC39318988 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239200 O=C(NCCc1c[nH]c2ccccc12)c1cnccn1 InChI=1S/C15H14N4O/c20-15(14-10-16-7-8-17-14)18-6-5-11-9-19-13-4-2-1-3-12(11)13/h1-4,7-10,19H,5-6H2,(H,18,20) XHZHVKZMLSMJMV-UHFFFAOYSA-N 114906 MLS000772601::N-[2-(1H-indol-3-yl)ethyl]-2-pyrazinecarboxamide::N-[2-(1H-indol-3-yl)ethyl]pyrazinamide::N-[2-(1H-indol-3-yl)ethyl]pyrazine-2-carboxamide::SMR000344610::cid_2537513 Oxysterols receptor LXR-beta 67502 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114906&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2537513 252664369 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239201 COc1ccc(cc1)C(=O)\C=C1/Sc2ccccc2N1C InChI=1S/C17H15NO2S/c1-18-14-5-3-4-6-16(14)21-17(18)11-15(19)12-7-9-13(20-2)10-8-12/h3-11H,1-2H3/b17-11- UQGDGKXDRXRBGM-BOPFTXTBSA-N 49771 (2Z)-1-(4-methoxyphenyl)-2-(3-methyl-1,3-benzothiazol-2-ylidene)ethanone::MLS000677440::SMR000286192::cid_2146420 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49771&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2146420 252630046 ZINC12466513 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239202 Cn1ccnc1SCC(=O)c1c[nH]c2ccccc12 InChI=1S/C14H13N3OS/c1-17-7-6-15-14(17)19-9-13(18)11-8-16-12-5-3-2-4-10(11)12/h2-8,16H,9H2,1H3 RCIDSNDVAIAUBB-UHFFFAOYSA-N 114907 1-(1H-indol-3-yl)-2-(1-methylimidazol-2-yl)sulfanyl-ethanone::1-(1H-indol-3-yl)-2-(1-methylimidazol-2-yl)sulfanylethanone::1-(1H-indol-3-yl)-2-[(1-methyl-2-imidazolyl)thio]ethanone::1-(1H-indol-3-yl)-2-[(1-methylimidazol-2-yl)thio]ethanone::MLS000516654::SMR000342832::cid_3894771 Oxysterols receptor LXR-beta 67479 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114907&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3894771 252664370 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239203 CCc1sc(cc1C)C(=O)N1CCc2ccccc12 InChI=1S/C16H17NOS/c1-3-14-11(2)10-15(19-14)16(18)17-9-8-12-6-4-5-7-13(12)17/h4-7,10H,3,8-9H2,1-2H3 KPGKYXJUDJZUCU-UHFFFAOYSA-N 49965 (5-ethyl-4-methyl-2-thienyl)-indolin-1-yl-methanone::2,3-dihydroindol-1-yl-(5-ethyl-4-methyl-2-thiophenyl)methanone::2,3-dihydroindol-1-yl-(5-ethyl-4-methyl-thiophen-2-yl)methanone::2,3-dihydroindol-1-yl-(5-ethyl-4-methylthiophen-2-yl)methanone::MLS000771226::SMR000376141::cid_2576382 Oxysterols receptor LXR-beta 67509 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49965&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2576382 252630239 ZINC03455992 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239204 Cc1ccc(NC(=O)c2ccccn2)c(Br)c1 InChI=1S/C13H11BrN2O/c1-9-5-6-11(10(14)8-9)16-13(17)12-4-2-3-7-15-12/h2-8H,1H3,(H,16,17) MOQSQIIRERDFDG-UHFFFAOYSA-N 49978 MLS000807205::N-(2-bromanyl-4-methyl-phenyl)pyridine-2-carboxamide::N-(2-bromo-4-methyl-phenyl)picolinamide::N-(2-bromo-4-methylphenyl)-2-pyridinecarboxamide::N-(2-bromo-4-methylphenyl)pyridine-2-carboxamide::SMR000376313::cid_2301666 Oxysterols receptor LXR-beta 67514 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49978&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2301666 252630252 ZINC03013918 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239206 CC(C)(C)C1CCC(CC1)=NNC(=S)Nc1cccnc1 InChI=1S/C16H24N4S/c1-16(2,3)12-6-8-13(9-7-12)19-20-15(21)18-14-5-4-10-17-11-14/h4-5,10-12H,6-9H2,1-3H3,(H2,18,20,21)/b19-13- XXQFUALXHWDNKJ-UYRXBGFRSA-N 114909 1-[(4-tert-butylcyclohexylidene)amino]-3-(3-pyridinyl)thiourea::1-[(4-tert-butylcyclohexylidene)amino]-3-(3-pyridyl)thiourea::1-[(4-tert-butylcyclohexylidene)amino]-3-pyridin-3-yl-thiourea::1-[(4-tert-butylcyclohexylidene)amino]-3-pyridin-3-ylthiourea::MLS001033837::SMR000385741::cid_3323342 Oxysterols receptor LXR-beta 67514 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114909&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3323342 252664371 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239207 OC(=O)c1ccc(cc1)\[NH+]=N\C=C\[CH-]c1ccccc1[N+]([O-])=O InChI=1S/C16H12N3O4/c20-16(21)13-7-9-14(10-8-13)18-17-11-3-5-12-4-1-2-6-15(12)19(22)23/h1-11H,(H,20,21)/q-1/p+1/b11-3+,18-17+ FQGPUAXAPGMDKZ-YREZNJBWSA-O 114910 4-[(2E)-2-[(E)-3-(2-nitrophenyl)prop-2-enylidene]hydrazinyl]benzoic acid::4-[(N'E)-N'-[(E)-3-(2-nitrophenyl)prop-2-enylidene]hydrazino]benzoic acid::MLS000774249::SMR000365070::cid_6892628 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114910&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6892628 252664372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239208 OC(=O)c1ccccc1SCC(=O)N1CCc2ccccc12 InChI=1S/C17H15NO3S/c19-16(18-10-9-12-5-1-3-7-14(12)18)11-22-15-8-4-2-6-13(15)17(20)21/h1-8H,9-11H2,(H,20,21) LEBUKXMEKYOCML-UHFFFAOYSA-N 114911 2-[(2-indolin-1-yl-2-keto-ethyl)thio]benzoic acid::2-[2-(2,3-dihydroindol-1-yl)-2-oxidanylidene-ethyl]sulfanylbenzoic acid::2-[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]sulfanylbenzoic acid::2-[[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]thio]benzoic acid::MLS000774577::SMR000372140::cid_3810088 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114911&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3810088 252664373 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239209 CC(=O)Nc1ccc(CN=Nc2nc3ccccc3s2)cc1 InChI=1S/C16H14N4OS/c1-11(21)18-13-8-6-12(7-9-13)10-17-20-16-19-14-4-2-3-5-15(14)22-16/h2-9H,10H2,1H3,(H,18,21) YHPDSGONSNFBIC-UHFFFAOYSA-N 43774 MLS001017252::N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]acetamide::N-[4-[(1,3-benzothiazol-2-ylhydrazinylidene)methyl]phenyl]ethanamide::N-[4-[(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide::N-[4-[(E)-(1,3-benzothiazol-2-ylhydrazono)methyl]phenyl]acetamide::SMR000353528::cid_220697 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43774&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896576 252624450 ZINC31601757 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239210 Cc1c(cccc1[N+]([O-])=O)C(=O)O[N-]C(=[NH2+])c1ccccn1 InChI=1S/C14H11N4O4/c1-9-10(5-4-7-12(9)18(20)21)14(19)22-17-13(15)11-6-2-3-8-16-11/h2-8H,1H3,(H-,15,17)/q-1/p+1 XKJUDIPSFBYWBO-UHFFFAOYSA-O 114912 2-methyl-3-nitro-benzoic acid [(Z)-[amino(2-pyridyl)methylene]amino] ester::2-methyl-3-nitrobenzoic acid [(Z)-[amino(2-pyridinyl)methylidene]amino] ester::MLS001012218::SMR000425211::[(Z)-[amino(pyridin-2-yl)methylidene]amino] 2-methyl-3-nitrobenzoate::[(Z)-[azanyl(pyridin-2-yl)methylidene]amino] 2-methyl-3-nitro-benzoate::cid_5346517 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114912&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5346517 252664374 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239211 Cn1cnc(NCc2ccccc2)c1[N+]([O-])=O InChI=1S/C11H12N4O2/c1-14-8-13-10(11(14)15(16)17)12-7-9-5-3-2-4-6-9/h2-6,8,12H,7H2,1H3 MIZWNLQEGHEAEO-UHFFFAOYSA-N 114913 1-methyl-5-nitro-N-(phenylmethyl)-4-imidazolamine::1-methyl-5-nitro-N-(phenylmethyl)imidazol-4-amine::Benzyl-(1-methyl-5-nitro-1H-imidazol-4-yl)-amine::MLS001049370::N-benzyl-1-methyl-5-nitroimidazol-4-amine::SMR000427361::benzyl-(1-methyl-5-nitro-imidazol-4-yl)amine::cid_3628746 Oxysterols receptor LXR-beta 67475 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114913&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3628746 252664375 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239212 COc1ccc(cc1)C(N)=NOC(=O)c1cccs1 InChI=1S/C13H12N2O3S/c1-17-10-6-4-9(5-7-10)12(14)15-18-13(16)11-3-2-8-19-11/h2-8H,1H3,(H2,14,15) OJNIWUCWEBOZLJ-UHFFFAOYSA-N 114914 2-thiophenecarboxylic acid [(Z)-[amino-(4-methoxyphenyl)methylidene]amino] ester::MLS000332613::SMR000435935::[(Z)-[amino-(4-methoxyphenyl)methylidene]amino] thiophene-2-carboxylate::[(Z)-[azanyl-(4-methoxyphenyl)methylidene]amino] thiophene-2-carboxylate::cid_5931120::thiophene-2-carboxylic acid [(Z)-[amino-(4-methoxyphenyl)methylene]amino] ester Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114914&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5931120 252664376 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239213 Oc1c(N=Nc2ccccc2)sc2ccccc12 InChI=1S/C14H10N2OS/c17-13-11-8-4-5-9-12(11)18-14(13)16-15-10-6-2-1-3-7-10/h1-9,17H NINPOLKSNFCLDI-UHFFFAOYSA-N 114772 (2Z)-2-(phenylhydrazinylidene)-1-benzothiophen-3-one::(2Z)-2-(phenylhydrazono)benzothiophen-3-one::2-(Phenyl-hydrazono)-benzo[b]thiophen-3-one::MLS000777106::SMR000413502::cid_5419037 Oxysterols receptor LXR-beta 67493 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114772&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5419037 252664247 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239214 CN1C(=O)C(CC(=O)Nc2ccc(F)cc2)N(Cc2cccs2)C1=S InChI=1S/C17H16FN3O2S2/c1-20-16(23)14(21(17(20)24)10-13-3-2-8-25-13)9-15(22)19-12-6-4-11(18)5-7-12/h2-8,14H,9-10H2,1H3,(H,19,22) FXLDSWUHIFVNKM-UHFFFAOYSA-N 114915 MLS000769586::N-(4-Fluoro-phenyl)-2-(1-methyl-5-oxo-3-thiophen-2-ylmethyl-2-thioxo-imidazolidin-4-yl)-acetamide::N-(4-fluorophenyl)-2-[1-methyl-5-oxidanylidene-2-sulfanylidene-3-(thiophen-2-ylmethyl)imidazolidin-4-yl]ethanamide::N-(4-fluorophenyl)-2-[1-methyl-5-oxo-2-sulfanylidene-3-(thiophen-2-ylmethyl)-4-imidazolidinyl]acetamide::N-(4-fluorophenyl)-2-[1-methyl-5-oxo-2-sulfanylidene-3-(thiophen-2-ylmethyl)imidazolidin-4-yl]acetamide::N-(4-fluorophenyl)-2-[5-keto-1-methyl-3-(2-thenyl)-2-thioxo-imidazolidin-4-yl]acetamide::SMR000434319::cid_3498692 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114915&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3498692 252664377 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239215 O=C(\C=C\c1ccccc1)c1c[nH]c2ccccc12 InChI=1S/C17H13NO/c19-17(11-10-13-6-2-1-3-7-13)15-12-18-16-9-5-4-8-14(15)16/h1-12,18H/b11-10+ KEZYTIZZNLLCGX-ZHACJKMWSA-N 114916 (E)-1-(1H-indol-3-yl)-3-phenyl-2-propen-1-one::(E)-1-(1H-indol-3-yl)-3-phenyl-prop-2-en-1-one::(E)-1-(1H-indol-3-yl)-3-phenylprop-2-en-1-one::MLS000737003::SMR000393960::cid_5355550 Oxysterols receptor LXR-beta 67404 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114916&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5355550 252664378 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239216 COc1cccc(NC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)c1 InChI=1S/C23H23N3O5/c1-30-17-6-4-5-16(13-17)24-23(29)22(28)19-14-26(20-8-3-2-7-18(19)20)15-21(27)25-9-11-31-12-10-25/h2-8,13-14H,9-12,15H2,1H3,(H,24,29) NSXJLPCYJCPGBE-UHFFFAOYSA-N 53252 2-keto-2-[1-(2-keto-2-morpholino-ethyl)indol-3-yl]-N-(3-methoxyphenyl)acetamide::MLS001117108::N-(3-methoxyphenyl)-2-[1-(2-morpholin-4-yl-2-oxidanylidene-ethyl)indol-3-yl]-2-oxidanylidene-ethanamide::N-(3-methoxyphenyl)-2-[1-(2-morpholin-4-yl-2-oxoethyl)indol-3-yl]-2-oxoacetamide::N-(3-methoxyphenyl)-2-[1-[2-(4-morpholinyl)-2-oxoethyl]-3-indolyl]-2-oxoacetamide::SMR000627195::cid_4091055 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53252&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4091055 252633384 ZINC18124911 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239217 c1cc(sc1-c1ccccn1)-c1ccccn1 InChI=1S/C14H10N2S/c1-3-9-15-11(5-1)13-7-8-14(17-13)12-6-2-4-10-16-12/h1-10H NIJMGWPTVYSTCQ-UHFFFAOYSA-N 114778 2-(5-pyridin-2-ylthiophen-2-yl)pyridine::2-[5-(2-pyridinyl)-2-thiophenyl]pyridine::2-[5-(2-pyridyl)-2-thienyl]pyridine::MLS000851103::SMR000457346::cid_2801704 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114778&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2801704 252664252 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239218 [O-][N+](=O)c1cc2C(=O)N(CCN3CCCC3)C(=O)c3cccc(c1)c23 InChI=1S/C18H17N3O4/c22-17-14-5-3-4-12-10-13(21(24)25)11-15(16(12)14)18(23)20(17)9-8-19-6-1-2-7-19/h3-5,10-11H,1-2,6-9H2 GBOQUHPYCRYKGV-UHFFFAOYSA-N 47509 5-nitro-2-(2-pyrrolidin-1-ylethyl)benzo[de]isoquinoline-1,3-dione::5-nitro-2-(2-pyrrolidinoethyl)benzo[de]isoquinoline-1,3-quinone::5-nitro-2-[2-(1-pyrrolidinyl)ethyl]benzo[de]isoquinoline-1,3-dione::MLS000766256::Pinafide::SMR000528858::cid_327045 Oxysterols receptor LXR-beta 67475 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=47509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=47509&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 327045 252627820 ZINC04217305 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239219 Clc1ccc(cc1)C(=O)CC=Nc1ccccc1C#N InChI=1S/C16H11ClN2O/c17-14-7-5-12(6-8-14)16(20)9-10-19-15-4-2-1-3-13(15)11-18/h1-8,10H,9H2 YATXVROEGMPFAC-UHFFFAOYSA-N 76617 2-[[(E)-3-(4-chlorophenyl)-3-keto-prop-1-enyl]amino]benzonitrile::2-[[(E)-3-(4-chlorophenyl)-3-oxidanylidene-prop-1-enyl]amino]benzenecarbonitrile::2-[[(E)-3-(4-chlorophenyl)-3-oxoprop-1-enyl]amino]benzonitrile::2-{[3-(4-chlorophenyl)-3-oxo-1-propenyl]amino}benzonitrile::MLS001180487::SMR000476404::cid_1713605 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76617&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91898185 252653794 ZINC00333987 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239220 Cc1ccc(cc1NC(=O)C1CCCC1)[N+]([O-])=O InChI=1S/C13H16N2O3/c1-9-6-7-11(15(17)18)8-12(9)14-13(16)10-4-2-3-5-10/h6-8,10H,2-5H2,1H3,(H,14,16) JKPHXNBCWLDKOP-UHFFFAOYSA-N 114917 MLS001000910::N-(2-methyl-5-nitro-phenyl)cyclopentanecarboxamide::N-(2-methyl-5-nitrophenyl)cyclopentanecarboxamide::SMR000497516::cid_898570 Oxysterols receptor LXR-beta 67507 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114917&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 898570 252664379 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239221 Cc1ccc(Nc2nc(N)c3ccccc3n2)cc1Cl InChI=1S/C15H13ClN4/c1-9-6-7-10(8-12(9)16)18-15-19-13-5-3-2-4-11(13)14(17)20-15/h2-8H,1H3,(H3,17,18,19,20) LFMFPKKYRXFHHZ-UHFFFAOYSA-N 114918 (4-aminoquinazolin-2-yl)-(3-chloro-4-methyl-phenyl)amine;hydrochloride::2-N-(3-chloro-4-methylphenyl)quinazoline-2,4-diamine;hydrochloride::MLS001008089::N2-(3-chloranyl-4-methyl-phenyl)quinazoline-2,4-diamine;hydrochloride::N2-(3-chloro-4-methylphenyl)quinazoline-2,4-diamine;hydrochloride::N~2~-(3-chloro-4-methylphenyl)-2,4-quinazolinediamine hydrochloride::SMR000498302::cid_2972826 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114918&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2227970 252664380 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239222 COc1ccc(C(=O)Nc2ccc3ccccc3c2)c(OC)c1 InChI=1S/C19H17NO3/c1-22-16-9-10-17(18(12-16)23-2)19(21)20-15-8-7-13-5-3-4-6-14(13)11-15/h3-12H,1-2H3,(H,20,21) AVLVKMUKWOULKR-UHFFFAOYSA-N 114919 2,4-dimethoxy-N-(2-naphthalenyl)benzamide::2,4-dimethoxy-N-(2-naphthyl)benzamide::2,4-dimethoxy-N-2-naphthylbenzamide::2,4-dimethoxy-N-naphthalen-2-yl-benzamide::2,4-dimethoxy-N-naphthalen-2-ylbenzamide::MLS001001550::SMR000496179::cid_795859 Oxysterols receptor LXR-beta 67524 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114919&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 795859 252664381 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239223 COc1ccc(NC(=O)c2cc3ccccc3cc2OC)cc1 InChI=1S/C19H17NO3/c1-22-16-9-7-15(8-10-16)20-19(21)17-11-13-5-3-4-6-14(13)12-18(17)23-2/h3-12H,1-2H3,(H,20,21) ARNIATVNQNPCHO-UHFFFAOYSA-N 114920 3-methoxy-N-(4-methoxyphenyl)-2-naphthalenecarboxamide::3-methoxy-N-(4-methoxyphenyl)-2-naphthamide::3-methoxy-N-(4-methoxyphenyl)naphthalene-2-carboxamide::MLS001008421::SMR000495913::cid_790574 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114920&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 790574 252664382 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239224 NC(=O)c1ccccc1NC(=O)c1ccc2ccccc2c1 InChI=1S/C18H14N2O2/c19-17(21)15-7-3-4-8-16(15)20-18(22)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H2,19,21)(H,20,22) MIHAZYWIRKMHBR-UHFFFAOYSA-N 114921 MLS001183382::N-(2-aminocarbonylphenyl)naphthalene-2-carboxamide::N-(2-carbamoylphenyl)-2-naphthalenecarboxamide::N-(2-carbamoylphenyl)-2-naphthamide::N-(2-carbamoylphenyl)naphthalene-2-carboxamide::SMR000502533::cid_787689 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114921&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 787689 252664383 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239225 Cc1ccc(cc1Br)N=CCC(=O)c1ccccc1 InChI=1S/C16H14BrNO/c1-12-7-8-14(11-15(12)17)18-10-9-16(19)13-5-3-2-4-6-13/h2-8,10-11H,9H2,1H3 FLVHSLFCOQAJKU-UHFFFAOYSA-N 114922 (E)-3-(3-bromo-4-methyl-anilino)-1-phenyl-prop-2-en-1-one::(E)-3-(3-bromo-4-methylanilino)-1-phenyl-2-propen-1-one::(E)-3-(3-bromo-4-methylanilino)-1-phenylprop-2-en-1-one::(E)-3-[(3-bromanyl-4-methyl-phenyl)amino]-1-phenyl-prop-2-en-1-one::MLS001181356::SMR000502610::cid_2290474 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114922&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899743 252664384 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239226 [O-][N+](=O)c1ccccc1CC(=O)NCCc1ccc(F)cc1 InChI=1S/C16H15FN2O3/c17-14-7-5-12(6-8-14)9-10-18-16(20)11-13-3-1-2-4-15(13)19(21)22/h1-8H,9-11H2,(H,18,20) JFPBGKRBGNJESW-UHFFFAOYSA-N 114923 MLS001183920::N-[2-(4-fluorophenyl)ethyl]-2-(2-nitrophenyl)acetamide::N-[2-(4-fluorophenyl)ethyl]-2-(2-nitrophenyl)ethanamide::SMR000502303::cid_1122457 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114923&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1122457 252664385 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239227 Cc1ccc(CNc2nc3ccccc3n2C)cc1 InChI=1S/C16H17N3/c1-12-7-9-13(10-8-12)11-17-16-18-14-5-3-4-6-15(14)19(16)2/h3-10H,11H2,1-2H3,(H,17,18) YHZLFFQZHKKCMG-UHFFFAOYSA-N 95918 (1-Methyl-1H-benzoimidazol-2-yl)-(4-methyl-benzyl)-amine::(1-methylbenzimidazol-2-yl)-(4-methylbenzyl)amine::1-methyl-N-[(4-methylphenyl)methyl]-2-benzimidazolamine::1-methyl-N-[(4-methylphenyl)methyl]benzimidazol-2-amine::MLS001206102::SMR000524108::cid_1090102 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95918&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1090102 164037162 ZINC00809655 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239228 COc1ccc(Cl)cc1C(=O)Nc1ccc2OCCOc2c1 InChI=1S/C16H14ClNO4/c1-20-13-4-2-10(17)8-12(13)16(19)18-11-3-5-14-15(9-11)22-7-6-21-14/h2-5,8-9H,6-7H2,1H3,(H,18,19) LOKRNXVIDGFNPM-UHFFFAOYSA-N 114924 5-Chloro-N-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-methoxy-benzamide::5-chloranyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methoxy-benzamide::5-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methoxy-benzamide::5-chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methoxybenzamide::MLS001202916::SMR000517085::cid_759617 Oxysterols receptor LXR-beta 67484 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114924&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 759617 252664386 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239229 Cn1c(CNc2ccc(F)cc2)nc2ccccc12 InChI=1S/C15H14FN3/c1-19-14-5-3-2-4-13(14)18-15(19)10-17-12-8-6-11(16)7-9-12/h2-9,17H,10H2,1H3 MWMHJOBJEKQQIB-UHFFFAOYSA-N 114925 (4-Fluoro-phenyl)-(1-methyl-1H-benzoimidazol-2-ylmethyl)-amine::(4-fluorophenyl)-[(1-methylbenzimidazol-2-yl)methyl]amine::4-fluoranyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline::4-fluoro-N-[(1-methyl-2-benzimidazolyl)methyl]aniline::4-fluoro-N-[(1-methylbenzimidazol-2-yl)methyl]aniline::MLS001204555::SMR000517589::cid_828085 Oxysterols receptor LXR-beta 67515 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114925&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 828085 252664387 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239230 Fc1ccc(cc1)-c1csc(Nc2ccccn2)n1 InChI=1S/C14H10FN3S/c15-11-6-4-10(5-7-11)12-9-19-14(17-12)18-13-3-1-2-8-16-13/h1-9H,(H,16,17,18) STXSPDSVGOEMPM-UHFFFAOYSA-N 93876 4-(4-fluorophenyl)-N-(2-pyridinyl)-2-thiazolamine::4-(4-fluorophenyl)-N-pyridin-2-yl-1,3-thiazol-2-amine::MLS001206910::SMR000524296::[4-(4-Fluoro-phenyl)-thiazol-2-yl]-pyridin-2-yl-amine::[4-(4-fluorophenyl)thiazol-2-yl]-(2-pyridyl)amine::cid_1092430 Oxysterols receptor LXR-beta 67602 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93876&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1092430 164035120 ZINC00813365 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239231 O=C(Nc1ccccc1)C(=O)c1c[nH]c2ccccc12 InChI=1S/C16H12N2O2/c19-15(16(20)18-11-6-2-1-3-7-11)13-10-17-14-9-5-4-8-12(13)14/h1-10,17H,(H,18,20) WMCHMBHWRLPJKP-UHFFFAOYSA-N 50331603 2-(1H-Indol-3-yl)-2-oxo-N-phenyl-acetamide::2-(1H-indol-3-yl)-2-oxo-N-phenylacetamide::CHEMBL356828::cid_3149448 Oxysterols receptor LXR-beta 67486 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50331603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50331603&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3149448 123110718 CHEMBL356828 ZINC03120963 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239232 Fc1ccccc1C(=O)Nc1ccc(Nc2ccccc2)cc1 InChI=1S/C19H15FN2O/c20-18-9-5-4-8-17(18)19(23)22-16-12-10-15(11-13-16)21-14-6-2-1-3-7-14/h1-13,21H,(H,22,23) JUSJIPDNBLLRIU-UHFFFAOYSA-N 77835 2-fluoranyl-N-(4-phenylazanylphenyl)benzamide::MLS000974597::N-(4-anilinophenyl)-2-fluoro-benzamide::N-(4-anilinophenyl)-2-fluorobenzamide::SMR000496820::cid_877468 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77835&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 877468 252654709 ZINC00275123 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239233 CCc1ccc(cc1)-n1nc2cc(C)c(N)cc2n1 InChI=1S/C15H16N4/c1-3-11-4-6-12(7-5-11)19-17-14-8-10(2)13(16)9-15(14)18-19/h4-9H,3,16H2,1-2H3 SNNHVUDPIOPIPM-UHFFFAOYSA-N 96061 2-(4-Ethyl-phenyl)-6-methyl-2H-benzotriazol-5-ylamine::2-(4-ethylphenyl)-6-methyl-5-benzotriazolamine::2-(4-ethylphenyl)-6-methyl-benzotriazol-5-amine::2-(4-ethylphenyl)-6-methylbenzotriazol-5-amine::MLS001211694::SMR000518909::[2-(4-ethylphenyl)-6-methyl-benzotriazol-5-yl]amine::cid_783935 Oxysterols receptor LXR-beta 67470 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 783935 164037305 ZINC00279698 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239234 Oc1cccc(NC(=O)c2c(O)c3ccccc3[nH]c2=O)c1 InChI=1S/C16H12N2O4/c19-10-5-3-4-9(8-10)17-15(21)13-14(20)11-6-1-2-7-12(11)18-16(13)22/h1-8,19H,(H,17,21)(H2,18,20,22) JFHRQAGLXHCZAR-UHFFFAOYSA-N 114926 4-Hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid (3-hydroxy-phenyl)-amide::4-hydroxy-N-(3-hydroxyphenyl)-2-keto-1H-quinoline-3-carboxamide::4-hydroxy-N-(3-hydroxyphenyl)-2-oxo-1H-quinoline-3-carboxamide::MLS001212834::N-(3-hydroxyphenyl)-4-oxidanyl-2-oxidanylidene-1H-quinoline-3-carboxamide::SMR000514506::cid_54683801 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114926&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 54683801 252664388 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239235 COCCNC(=O)Cn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O InChI=1S/C19H18ClN3O3/c1-26-11-10-21-17(24)12-23-19(25)16-5-3-2-4-15(16)18(22-23)13-6-8-14(20)9-7-13/h2-9H,10-12H2,1H3,(H,21,24) PLTRDCDUCSPIMS-UHFFFAOYSA-N 114927 2-[4-(4-chlorophenyl)-1-keto-phthalazin-2-yl]-N-(2-methoxyethyl)acetamide::2-[4-(4-chlorophenyl)-1-oxidanylidene-phthalazin-2-yl]-N-(2-methoxyethyl)ethanamide::2-[4-(4-chlorophenyl)-1-oxo-2-phthalazinyl]-N-(2-methoxyethyl)acetamide::2-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-N-(2-methoxyethyl)acetamide::2-[4-(4-chlorophenyl)-1-oxophthalazin-2-yl]-N-(2-methoxyethyl)acetamide::MLS001196123::SMR000558461::cid_1829088 Oxysterols receptor LXR-beta 67478 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114927&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1829088 252664389 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239236 COCCCNc1nc2c(nnn2c2ccccc12)-c1ccc(C)cc1 InChI=1S/C20H21N5O/c1-14-8-10-15(11-9-14)18-20-22-19(21-12-5-13-26-2)16-6-3-4-7-17(16)25(20)24-23-18/h3-4,6-11H,5,12-13H2,1-2H3,(H,21,22) AXHXDRWIGKUQRL-UHFFFAOYSA-N 114928 3-methoxypropyl-[3-(p-tolyl)triazolo[1,5-a]quinazolin-5-yl]amine::MLS001199148::N-(3-methoxypropyl)-3-(4-methylphenyl)-5-triazolo[1,5-a]quinazolinamine::N-(3-methoxypropyl)-3-(4-methylphenyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine::N-(3-methoxypropyl)-3-(4-methylphenyl)[1,2,3]triazolo[1,5-a]quinazolin-5-amine::N-(3-methoxypropyl)-3-(4-methylphenyl)triazolo[1,5-a]quinazolin-5-amine::SMR000563000::cid_16824683 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114928&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16824683 252664390 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239237 Oc1ccc(N=Nc2ccccc2)o1 InChI=1S/C10H8N2O2/c13-10-7-6-9(14-10)12-11-8-4-2-1-3-5-8/h1-7,13H DCKAMYOOABZMCH-UHFFFAOYSA-N 114929 (5E)-5-(phenylhydrazinylidene)-2-furanone::(5E)-5-(phenylhydrazinylidene)furan-2-one::(5E)-5-(phenylhydrazono)furan-2-one::MLS001216481::SMR000544177::cid_5601352 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114929&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5601352 252664391 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239238 COc1ccc(cc1)-c1nc2ccccn2c1Cl InChI=1S/C14H11ClN2O/c1-18-11-7-5-10(6-8-11)13-14(15)17-9-3-2-4-12(17)16-13/h2-9H,1H3 HKIYOGUMCXKKRW-UHFFFAOYSA-N 114930 3-chloranyl-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine::3-chloro-2-(4-methoxyphenyl)imidazo[1,2-a]pyridine::MLS001166219::SMR000549996::cid_1104473 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114930&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1104473 252664392 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239239 Clc1ccc(cc1)-c1cn2cc(Cl)ccc2n1 InChI=1S/C13H8Cl2N2/c14-10-3-1-9(2-4-10)12-8-17-7-11(15)5-6-13(17)16-12/h1-8H CFINUJBABHRHDT-UHFFFAOYSA-N 114931 6-chloranyl-2-(4-chlorophenyl)imidazo[1,2-a]pyridine::6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine::MLS001166240::SMR000549995::cid_717647 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114931&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 717647 252664393 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239240 Oc1cccc(\C=C\c2ccc3cccc(O)c3n2)c1 InChI=1S/C17H13NO2/c19-15-5-1-3-12(11-15)7-9-14-10-8-13-4-2-6-16(20)17(13)18-14/h1-11,19-20H/b9-7+ ZGCNQHDVSASYMK-VQHVLOKHSA-N 114932 2-[(E)-2-(3-hydroxyphenyl)ethenyl]-8-quinolinol::2-[(E)-2-(3-hydroxyphenyl)ethenyl]quinolin-8-ol::2-[(E)-2-(3-hydroxyphenyl)vinyl]quinolin-8-ol::MLS001196201::SMR000558527::cid_5837141 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114932&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5837141 252664394 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239241 Cc1cccc2=C(NNc3ccccc3)C(=O)N=c12 InChI=1S/C15H13N3O/c1-10-6-5-9-12-13(10)16-15(19)14(12)18-17-11-7-3-2-4-8-11/h2-9,17H,1H3,(H,16,18,19) PCYWVEYLUIIDSS-UHFFFAOYSA-N 114800 (3Z)-7-methyl-1H-indole-2,3-dione 3-(phenylhydrazone)::7-methyl-3-(2-phenylhydrazinyl)indol-2-one::7-methyl-3-(N'-phenylhydrazino)indol-2-one::7-methyl-3-(phenylhydrazo)-2-indolone::MLS001194880::SMR000554656::cid_5286407 Oxysterols receptor LXR-beta 67498 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114800&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5286407 252664273 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239242 Cc1ccc(Nc2nc(cs2)-c2cccnc2)cc1C InChI=1S/C16H15N3S/c1-11-5-6-14(8-12(11)2)18-16-19-15(10-20-16)13-4-3-7-17-9-13/h3-10H,1-2H3,(H,18,19) YYQJMUZUTIQOHV-UHFFFAOYSA-N 76699 (3,4-dimethylphenyl)-[4-(3-pyridyl)thiazol-2-yl]amine::MLS001198635::N-(3,4-dimethylphenyl)-4-(3-pyridinyl)-2-thiazolamine::N-(3,4-dimethylphenyl)-4-pyridin-3-yl-1,3-thiazol-2-amine::SMR000558990::cid_972507 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76699&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 972507 252653876 ZINC00612752 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239243 Oc1ccccc1-c1cc([nH]n1)-c1ccc(Cl)cc1 InChI=1S/C15H11ClN2O/c16-11-7-5-10(6-8-11)13-9-14(18-17-13)12-3-1-2-4-15(12)19/h1-9,19H,(H,17,18) ZXVNJVRABSCRGU-UHFFFAOYSA-N 114933 (6Z)-6-[5-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6Z)-6-[5-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-6-[5-(4-chlorophenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::MLS001182178::SMR000567869::cid_5333851 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114933&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5333851 252664395 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239244 OC(=O)C(=O)C(=C/c1ccsc1)\c1ccc2ccccc2n1 InChI=1S/C17H11NO3S/c19-16(17(20)21)13(9-11-7-8-22-10-11)15-6-5-12-3-1-2-4-14(12)18-15/h1-10H,(H,20,21)/b13-9- XEIOVMVRJOZNBF-LCYFTJDESA-N 53171 (Z)-2-keto-3-(2-quinolyl)-4-(3-thienyl)but-3-enoic acid::(Z)-2-oxidanylidene-3-quinolin-2-yl-4-thiophen-3-yl-but-3-enoic acid::(Z)-2-oxo-3-(2-quinolinyl)-4-(3-thiophenyl)-3-butenoic acid::(Z)-2-oxo-3-quinolin-2-yl-4-thiophen-3-ylbut-3-enoic acid::MLS001176972::SMR000591295::cid_6529291 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53171&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6529291 252633303 ZINC04811996 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239245 C(Sc1ccccn1)c1nc2ccccc2s1 InChI=1S/C13H10N2S2/c1-2-6-11-10(5-1)15-13(17-11)9-16-12-7-3-4-8-14-12/h1-8H,9H2 DWVNQWFCVZOJDG-UHFFFAOYSA-N 114934 2-(pyridin-2-ylsulfanylmethyl)-1,3-benzothiazole::2-[(2-pyridinylthio)methyl]-1,3-benzothiazole::2-[(2-pyridylthio)methyl]-1,3-benzothiazole::MLS001176964::SMR000588927::cid_2417513 Oxysterols receptor LXR-beta 67464 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114934&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2417513 252664396 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239246 COc1cc(SC)ccc1C(=O)Nc1ccc2CCCc2c1 InChI=1S/C18H19NO2S/c1-21-17-11-15(22-2)8-9-16(17)18(20)19-14-7-6-12-4-3-5-13(12)10-14/h6-11H,3-5H2,1-2H3,(H,19,20) LHUOLVDDERDQNF-UHFFFAOYSA-N 114935 MLS001174493::N-(2,3-dihydro-1H-inden-5-yl)-2-methoxy-4-(methylthio)benzamide::N-(2,3-dihydro-1H-inden-5-yl)-2-methoxy-4-methylsulfanyl-benzamide::N-(2,3-dihydro-1H-inden-5-yl)-2-methoxy-4-methylsulfanylbenzamide::N-indan-5-yl-2-methoxy-4-(methylthio)benzamide::SMR000588656::cid_2124983 Oxysterols receptor LXR-beta 67491 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114935&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2124983 252664397 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239247 Cc1csc(NC(=O)c2ccc3ccccc3n2)n1 InChI=1S/C14H11N3OS/c1-9-8-19-14(15-9)17-13(18)12-7-6-10-4-2-3-5-11(10)16-12/h2-8H,1H3,(H,15,17,18) ZXLDSLCUIHEUDZ-UHFFFAOYSA-N 76709 MLS001177468::N-(4-methyl-1,3-thiazol-2-yl)quinoline-2-carboxamide::N-(4-methyl-2-thiazolyl)-2-quinolinecarboxamide::N-(4-methylthiazol-2-yl)quinaldamide::SMR000588905::cid_2105353 Oxysterols receptor LXR-beta 67568 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76709&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2105353 252653886 ZINC02642555 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239248 COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccc2OCOc2c1 InChI=1S/C20H18N2O5/c1-25-20(24)16(8-13-10-21-15-5-3-2-4-14(13)15)22-19(23)12-6-7-17-18(9-12)27-11-26-17/h2-7,9-10,16,21H,8,11H2,1H3,(H,22,23)/t16-/m1/s1 BNAZOOCFECXZBZ-MRXNPFEDSA-N 72954 (2R)-2-[[1,3-benzodioxol-5-yl(oxo)methyl]amino]-3-(1H-indol-3-yl)propanoic acid methyl ester::(2R)-3-(1H-indol-3-yl)-2-(piperonyloylamino)propionic acid methyl ester::MLS001172456::SMR000589284::cid_2408827::methyl (2R)-2-(1,3-benzodioxol-5-ylcarbonylamino)-3-(1H-indol-3-yl)propanoate::methyl (2R)-2-(1,3-benzodioxole-5-carbonylamino)-3-(1H-indol-3-yl)propanoate Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72954&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2408827 252650205 ZINC03293226 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239249 Fc1ccccc1NC(=O)Nc1nc2ccccc2[nH]1 InChI=1S/C14H11FN4O/c15-9-5-1-2-6-10(9)18-14(20)19-13-16-11-7-3-4-8-12(11)17-13/h1-8H,(H3,16,17,18,19,20) XEEVCOVNDDLYGV-UHFFFAOYSA-N 76719 1-(1H-benzimidazol-2-yl)-3-(2-fluorophenyl)urea::MLS001172858::SMR000589803::cid_4963407 Oxysterols receptor LXR-beta 67479 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76719&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4963407 252653896 ZINC05267382 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239250 Cc1c(oc2ccccc12)C(=O)Nc1ccc(C)cn1 InChI=1S/C16H14N2O2/c1-10-7-8-14(17-9-10)18-16(19)15-11(2)12-5-3-4-6-13(12)20-15/h3-9H,1-2H3,(H,17,18,19) ZGUGKFSCLHUHDE-UHFFFAOYSA-N 76740 3-methyl-N-(5-methyl-2-pyridinyl)-2-benzofurancarboxamide::3-methyl-N-(5-methyl-2-pyridyl)coumarilamide::3-methyl-N-(5-methylpyridin-2-yl)-1-benzofuran-2-carboxamide::MLS001077863::SMR000709549::cid_18106749 Oxysterols receptor LXR-beta 67463 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18106749 252653917 ZINC12523074 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239251 Fc1ccccc1NC(=O)C(=C\c1ccc[nH]1)\C#N InChI=1S/C14H10FN3O/c15-12-5-1-2-6-13(12)18-14(19)10(9-16)8-11-4-3-7-17-11/h1-8,17H,(H,18,19)/b10-8+ UHHKNRWTEXPYQI-CSKARUKUSA-N 114936 (E)-2-cyano-N-(2-fluorophenyl)-3-(1H-pyrrol-2-yl)-2-propenamide::(E)-2-cyano-N-(2-fluorophenyl)-3-(1H-pyrrol-2-yl)acrylamide::(E)-2-cyano-N-(2-fluorophenyl)-3-(1H-pyrrol-2-yl)prop-2-enamide::MLS001224857::SMR000678606::cid_24818453 Oxysterols receptor LXR-beta 67456 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114936&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24818453 252664398 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239252 Cc1ccnc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1 InChI=1S/C15H12N4O3/c1-8-4-5-16-12(6-8)19-13(20)9-2-3-10-11(7-9)18-15(22)14(21)17-10/h2-7H,1H3,(H,17,21)(H,18,22)(H,16,19,20) UHGWFOUJHSISIJ-UHFFFAOYSA-N 114937 2,3-diketo-N-(4-methyl-2-pyridyl)-1,4-dihydroquinoxaline-6-carboxamide::MLS001158311::N-(4-methyl-2-pyridinyl)-2,3-dioxo-1,4-dihydroquinoxaline-6-carboxamide::N-(4-methylpyridin-2-yl)-2,3-bis(oxidanylidene)-1,4-dihydroquinoxaline-6-carboxamide::N-(4-methylpyridin-2-yl)-2,3-dioxo-1,4-dihydroquinoxaline-6-carboxamide::SMR000652335::cid_17583860 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114937&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 17583860 252664399 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239253 O=c1n2CCc3c([nH]c4ccccc34)-c2nc2ccccc12 InChI=1S/C18H13N3O/c22-18-13-6-2-4-8-15(13)20-17-16-12(9-10-21(17)18)11-5-1-3-7-14(11)19-16/h1-8,19H,9-10H2 ACVGWSKVRYFWRP-UHFFFAOYSA-N 50131046 8,13-Dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL85139::cid_65752::rutaecarpine Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131046&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 65752 104022288 CHEMBL85139 C09238 ZINC00898237 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239254 C[C@]12[C@H]([C@H]3COc4ccccc4[C@@H]3N1C(=O)c1cc(Cl)ccc1NC2=O)c1ccccc1 InChI=1S/C26H21ClN2O3/c1-26-22(15-7-3-2-4-8-15)19-14-32-21-10-6-5-9-17(21)23(19)29(26)24(30)18-13-16(27)11-12-20(18)28-25(26)31/h2-13,19,22-23H,14H2,1H3,(H,28,31)/t19-,22+,23+,26-/m1/s1 GHYZYEWFTIVWLF-WVIBYCHQSA-N 77929 MLS002174170::SMR001261337::cid_25102468 Oxysterols receptor LXR-beta 67399 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77929&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102468 242053623 ZINC05687435 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239255 COC(=O)[C@]1(C)N[C@H](CN(C)C(C)=O)[C@H]2[C@@H]1C(=O)N(Cc1ccccc1)C2=O InChI=1S/C20H25N3O5/c1-12(24)22(3)11-14-15-16(20(2,21-14)19(27)28-4)18(26)23(17(15)25)10-13-8-6-5-7-9-13/h5-9,14-16,21H,10-11H2,1-4H3/t14-,15+,16-,20-/m1/s1 JYLSGQMEINLSOT-UIVXKWKOSA-N 114938 (1S,3R,3aS,6aR)-1-[[acetyl(methyl)amino]methyl]-3-methyl-4,6-dioxo-5-(phenylmethyl)-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylic acid methyl ester;2,2,2-trifluoroacetic acid::(1S,3R,3aS,6aR)-1-[[acetyl(methyl)amino]methyl]-5-benzyl-4,6-diketo-3-methyl-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylic acid methyl ester;2,2,2-trifluoroacetic acid::MLS002476886::SMR001398809::cid_44246851::methyl (1S,3R,3aS,6aR)-1-[[acetyl(methyl)amino]methyl]-5-benzyl-3-methyl-4,6-dioxo-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate;2,2,2-trifluoroacetic acid::methyl (1S,3R,3aS,6aR)-1-[[ethanoyl(methyl)amino]methyl]-3-methyl-4,6-bis(oxidanylidene)-5-(phenylmethyl)-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate;2,2,2-tris(fluoranyl)ethanoic acid Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114938&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44246852 252664400 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239256 COc1ccc(cc1)-n1nc2cc(C)c(N)c(Br)c2n1 InChI=1S/C14H13BrN4O/c1-8-7-11-14(12(15)13(8)16)18-19(17-11)9-3-5-10(20-2)6-4-9/h3-7H,16H2,1-2H3 KDTXZMQLDJGXRG-UHFFFAOYSA-N 34628 4-bromanyl-2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-amine::4-bromo-2-(4-methoxyphenyl)-6-methyl-2H-1,2,3-benzotriazol-5-amine::4-bromo-2-(4-methoxyphenyl)-6-methyl-5-benzotriazolamine::4-bromo-2-(4-methoxyphenyl)-6-methylbenzotriazol-5-amine::MLS000052623::SMR000082196::[4-bromo-2-(4-methoxyphenyl)-6-methyl-benzotriazol-5-yl]amine::cid_2236497 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34628&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2236497 252617279 ZINC02884195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239257 COc1ccc(cc1)-c1noc(CCC(=O)N2CCN(CC2)c2cccc(C)c2)n1 InChI=1S/C23H26N4O3/c1-17-4-3-5-19(16-17)26-12-14-27(15-13-26)22(28)11-10-21-24-23(25-30-21)18-6-8-20(29-2)9-7-18/h3-9,16H,10-15H2,1-2H3 ZIYUMIXNJRJNEJ-UHFFFAOYSA-N 54579 3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-[4-(3-methylphenyl)-1-piperazinyl]-1-propanone::3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-[4-(3-methylphenyl)piperazin-1-yl]propan-1-one::3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-[4-(m-tolyl)piperazino]propan-1-one::KUC103408N::UNM-0000306125::cid_42628046 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54579&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42628046 252634605 ZINC61948860 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239258 COc1cccc(c1)C(=O)Cn1c2ccccc2n(C)c1=N InChI=1S/C17H17N3O2/c1-19-14-8-3-4-9-15(14)20(17(19)18)11-16(21)12-6-5-7-13(10-12)22-2/h3-10,18H,11H2,1-2H3 OPTVSQKGGWKAQN-UHFFFAOYSA-N 94708 2-(2-azanylidene-3-methyl-benzimidazol-1-yl)-1-(3-methoxyphenyl)ethanone;hydrobromide::2-(2-imino-3-methyl-1-benzimidazolyl)-1-(3-methoxyphenyl)ethanone;hydrobromide::2-(2-imino-3-methyl-benzimidazol-1-yl)-1-(3-methoxyphenyl)ethanone;hydrobromide::2-(2-imino-3-methylbenzimidazol-1-yl)-1-(3-methoxyphenyl)ethanone;hydrobromide::MLS000078854::SMR000040462::cid_6603194 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=94708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=94708&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 659373 164035952 ZINC00507990 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239259 [O-][N+](=O)c1ccc(cc1)C(=O)N1CCOCC1 InChI=1S/C11H12N2O4/c14-11(12-5-7-17-8-6-12)9-1-3-10(4-2-9)13(15)16/h1-4H,5-8H2 VGGZQWDRWOXJTA-UHFFFAOYSA-N 114939 4-morpholinyl-(4-nitrophenyl)methanone::MLS002637737::SMR001470003::cid_220838::morpholin-4-yl-(4-nitrophenyl)methanone::morpholino-(4-nitrophenyl)methanone Oxysterols receptor LXR-beta 67395 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 220838 252664401 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239260 Cc1ccc2nc(sc2c1)-c1ccc(NC(=O)COC(=O)c2ccc(Br)o2)cc1 InChI=1S/C21H15BrN2O4S/c1-12-2-7-15-17(10-12)29-20(24-15)13-3-5-14(6-4-13)23-19(25)11-27-21(26)16-8-9-18(22)28-16/h2-10H,11H2,1H3,(H,23,25) FEUSUMOGHXMVBM-UHFFFAOYSA-N 49626 5-bromo-2-furancarboxylic acid [2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] ester::5-bromofuran-2-carboxylic acid [2-keto-2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]ethyl] ester::MLS000402446::SMR000263667::[2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] 5-bromofuran-2-carboxylate::[2-[[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]amino]-2-oxidanylidene-ethyl] 5-bromanylfuran-2-carboxylate::cid_2335783 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49626&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2335783 252629901 ZINC03217134 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239261 Nc1ccccc1C=C1Cc2ccccc2C1=O InChI=1S/C16H13NO/c17-15-8-4-2-6-12(15)10-13-9-11-5-1-3-7-14(11)16(13)18/h1-8,10H,9,17H2 VDYQCZPANJIJKH-UHFFFAOYSA-N 95940 2-(2-aminobenzylidene)indan-1-one::2-[(2-aminophenyl)methylidene]-3H-inden-1-one::MLS002694438::SMR001560367::cid_255770 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95940&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 255770 164037184 ZINC12410405 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239262 CC1(C)NC(=S)C(C)(C)N1N=O InChI=1S/C7H13N3OS/c1-6(2)5(12)8-7(3,4)10(6)9-11/h1-4H3,(H,8,12) LEBXDEWWHIETJM-UHFFFAOYSA-N 114940 2,2,5,5-tetramethyl-1-nitroso-4-imidazolidinethione::2,2,5,5-tetramethyl-1-nitroso-imidazolidine-4-thione::2,2,5,5-tetramethyl-1-nitrosoimidazolidine-4-thione::MLS002695136::SMR001561048::cid_4038956 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114940&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4038956 252664402 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239263 ClCCN(CCCl)c1ccc(CNNC(=O)Cc2c[nH]c3ccccc23)cc1 InChI=1S/C21H24Cl2N4O/c22-9-11-27(12-10-23)18-7-5-16(6-8-18)14-25-26-21(28)13-17-15-24-20-4-2-1-3-19(17)20/h1-8,15,24-25H,9-14H2,(H,26,28) WKLAUOSMKVLKIR-UHFFFAOYSA-N 114941 MLS002693508::N'-[4-[bis(2-chloroethyl)amino]benzyl]-2-(1H-indol-3-yl)acetohydrazide::N'-[[4-[bis(2-chloroethyl)amino]phenyl]methyl]-2-(1H-indol-3-yl)acetohydrazide::N'-[[4-[bis(2-chloroethyl)amino]phenyl]methyl]-2-(1H-indol-3-yl)ethanehydrazide::SMR001559459::cid_248411 Oxysterols receptor LXR-beta 67513 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114941&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 248411 252664403 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239264 Cc1ccc(C(=O)C2CC2)c(C)c1 InChI=1S/C12H14O/c1-8-3-6-11(9(2)7-8)12(13)10-4-5-10/h3,6-7,10H,4-5H2,1-2H3 CENWGMGAFRZWTJ-UHFFFAOYSA-N 114942 MLS002693749::SMR001559691::cid_96396::cyclopropyl-(2,4-dimethylphenyl)methanone Oxysterols receptor LXR-beta 67446 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114942&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 96396 252664404 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239265 C(=Cc1ccc2ccccc2n1)c1c[nH]c2ccccc12 InChI=1S/C19H14N2/c1-3-7-18-14(5-1)9-11-16(21-18)12-10-15-13-20-19-8-4-2-6-17(15)19/h1-13,20H/b12-10+ XBSNGDJJHAYDLC-ZRDIBKRKSA-N 95924 2-[2-(1H-indol-3-yl)ethenyl]quinoline::2-[2-(1H-indol-3-yl)vinyl]quinoline::MLS002693997::SMR001559931::cid_253632 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95924&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 253632 164037168 ZINC08616443 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239266 C(=Cc1nccc2ccccc12)c1c[nH]c2ccccc12 InChI=1S/C19H14N2/c1-2-6-16-14(5-1)11-12-20-19(16)10-9-15-13-21-18-8-4-3-7-17(15)18/h1-13,21H GXWLLYOLXFYXAT-UHFFFAOYSA-N 114822 1-[2-(1H-indol-3-yl)ethenyl]isoquinoline::1-[2-(1H-indol-3-yl)vinyl]isoquinoline::MLS002694045::SMR001559978::cid_254080 Oxysterols receptor LXR-beta 67588 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114822&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 254080 252664293 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239267 Cc1cc(ccc1N)-c1nc2ccccc2s1 InChI=1S/C14H12N2S/c1-9-8-10(6-7-11(9)15)14-16-12-4-2-3-5-13(12)17-14/h2-8H,15H2,1H3 IDBCUMFOZBUJCL-UHFFFAOYSA-N 50141278 2-(4-Amino-3-methylphenyl)benzothiazole::4-(3H-1lambda*4*-Benzothiazol-2-yl)-2-methyl-phenylamine::4-(benzo[d]thiazol-2-yl)-2-methylbenzenamine::4-Benzothiazol-2-yl-2-methyl-phenyl amine::4-Benzothiazol-2-yl-2-methyl-phenylamine::CHEMBL11825::cid_384525 Oxysterols receptor LXR-beta 67649 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141278&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search BM8 6EOY 384525 104030737 CHEMBL11825 ZINC00006701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239268 Cc1cc(ccc1N)-c1nc2cc(F)ccc2s1 InChI=1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3 IFWLHIIUGSEKKE-UHFFFAOYSA-N 93929 4-(5-fluoranyl-1,3-benzothiazol-2-yl)-2-methyl-aniline::4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylaniline::MLS002702467::SMR001566028::[4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methyl-phenyl]amine::cid_396813 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93929&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 396813 164035173 ZINC00008702 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239269 CCN(CC)CCCNc1nc2ccccc2c2[nH]c3ccc(OC)cc3c12 InChI=1S/C23H28N4O/c1-4-27(5-2)14-8-13-24-23-21-18-15-16(28-3)11-12-20(18)25-22(21)17-9-6-7-10-19(17)26-23/h6-7,9-12,15,25H,4-5,8,13-14H2,1-3H3,(H,24,26) HGILUFKJFSZULZ-UHFFFAOYSA-N 114943 MLS002702147::N',N'-diethyl-N-(8-methoxy-11H-indolo[3,2-c]quinolin-6-yl)propane-1,3-diamine;hydrochloride::SMR001565712::cid_379559::diethyl-[3-[(8-methoxy-11H-indolo[3,2-c]quinolin-6-yl)amino]propyl]amine;hydrochloride Oxysterols receptor LXR-beta 67524 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114943&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 379560 252664405 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239270 CNc1c2cccc(C)c2nc2c(cccc12)C(=O)NCCN(C)C InChI=1S/C20H24N4O/c1-13-7-5-8-14-17(13)23-19-15(18(14)21-2)9-6-10-16(19)20(25)22-11-12-24(3)4/h5-10H,11-12H2,1-4H3,(H,21,23)(H,22,25) VDPPTSGZVLYGQR-UHFFFAOYSA-N 114944 MLS002702420::N-[2-(dimethylamino)ethyl]-5-methyl-9-(methylamino)-4-acridinecarboxamide;hydrochloride::N-[2-(dimethylamino)ethyl]-5-methyl-9-(methylamino)acridine-4-carboxamide;hydrochloride::SMR001565982::cid_392739 Oxysterols receptor LXR-beta 67456 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114944&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 392740 252664406 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239271 Nc1ccccc1-n1nc2ccc3ccccc3c2n1 InChI=1S/C16H12N4/c17-13-7-3-4-8-15(13)20-18-14-10-9-11-5-1-2-6-12(11)16(14)19-20/h1-10H,17H2 WMCKDNPVZDYHGP-UHFFFAOYSA-N 114825 (2-benzo[e]benzotriazol-2-ylphenyl)amine::2-(2-benzo[e]benzotriazolyl)aniline::2-benzo[e]benzotriazol-2-ylaniline::MLS003106484::SMR001821386::cid_292642 Oxysterols receptor LXR-beta 67523 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114825&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 292642 252664296 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239272 Cc1cc2ccccn2c1C(=S)NC(=O)c1ccc(C)cc1 InChI=1S/C18H16N2OS/c1-12-6-8-14(9-7-12)17(21)19-18(22)16-13(2)11-15-5-3-4-10-20(15)16/h3-11H,1-2H3,(H,19,21,22) IUAHAUYRPYRGMM-UHFFFAOYSA-N 114945 4-methyl-N-(2-methylindolizin-3-yl)carbothioyl-benzamide::4-methyl-N-(2-methylindolizine-3-carbothioyl)benzamide::4-methyl-N-[(2-methyl-3-indolizinyl)-sulfanylidenemethyl]benzamide::MLS001004728::SMR000348365::cid_5116624 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114945&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5116624 252664407 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239273 COc1cccc(CC(=O)Nc2ccc3n(-c4ccc(cc4)C(C)(C)C)n(C)c(=O)c3c2)c1 InChI=1S/C27H29N3O3/c1-27(2,3)19-9-12-21(13-10-19)30-24-14-11-20(17-23(24)26(32)29(30)4)28-25(31)16-18-7-6-8-22(15-18)33-5/h6-15,17H,16H2,1-5H3,(H,28,31) HGTGQIKAAQMYIY-UHFFFAOYSA-N 114946 MLS003119390::N-[1-(4-tert-butylphenyl)-2-methyl-3-oxidanylidene-indazol-5-yl]-2-(3-methoxyphenyl)ethanamide::N-[1-(4-tert-butylphenyl)-2-methyl-3-oxo-5-indazolyl]-2-(3-methoxyphenyl)acetamide::N-[1-(4-tert-butylphenyl)-2-methyl-3-oxoindazol-5-yl]-2-(3-methoxyphenyl)acetamide::N-[1-(4-tert-butylphenyl)-3-keto-2-methyl-indazolin-5-yl]-2-(3-methoxyphenyl)acetamide::SMR001275335::cid_46943948 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114946&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46943948 252664408 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239275 Cc1onc(c1C(=O)OCC(=O)c1ccc(F)cc1)-c1ccccc1 InChI=1S/C19H14FNO4/c1-12-17(18(21-25-12)14-5-3-2-4-6-14)19(23)24-11-16(22)13-7-9-15(20)10-8-13/h2-10H,11H2,1H3 GNYXIALVNFGQBP-UHFFFAOYSA-N 114948 5-methyl-3-phenyl-4-isoxazolecarboxylic acid [2-(4-fluorophenyl)-2-oxoethyl] ester::5-methyl-3-phenyl-isoxazole-4-carboxylic acid [2-(4-fluorophenyl)-2-keto-ethyl] ester::MLS002180420::SMR001269450::[2-(4-fluorophenyl)-2-oxidanylidene-ethyl] 5-methyl-3-phenyl-1,2-oxazole-4-carboxylate::[2-(4-fluorophenyl)-2-oxoethyl] 5-methyl-3-phenyl-1,2-oxazole-4-carboxylate::cid_2629614 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114948&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2629614 252664410 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239276 C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@@H]1C[C@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O InChI=1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3/t10-,15-,16+,17-,21+,26+/m0/s1 XDXDZDZNSLXDNA-LGVQOGFTSA-N 114949 (7R,9R)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethanoyl-6,9,11-tris(oxidanyl)-8,10-dihydro-7H-tetracene-5,12-dione::(7R,9R)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-quinone::(7R,9R)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione::(7R,9R)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione::MLS002474519::SMR001398688::cid_151582 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114949&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 151582 252664411 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239277 CN(CC(=O)Nc1cccc(F)c1)C(=O)c1cccc(c1)S(=O)(=O)N1CCN(Cc2ccccc2)CC1 InChI=1S/C27H29FN4O4S/c1-30(20-26(33)29-24-11-6-10-23(28)18-24)27(34)22-9-5-12-25(17-22)37(35,36)32-15-13-31(14-16-32)19-21-7-3-2-4-8-21/h2-12,17-18H,13-16,19-20H2,1H3,(H,29,33) KABGMURCGUBZDV-UHFFFAOYSA-N 114950 3-(4-benzylpiperazin-1-yl)sulfonyl-N-[2-(3-fluoroanilino)-2-oxoethyl]-N-methylbenzamide::3-(4-benzylpiperazino)sulfonyl-N-[2-(3-fluoroanilino)-2-keto-ethyl]-N-methyl-benzamide::MLS002180376::N-[2-(3-fluoroanilino)-2-oxoethyl]-N-methyl-3-[[4-(phenylmethyl)-1-piperazinyl]sulfonyl]benzamide::N-[2-[(3-fluorophenyl)amino]-2-oxidanylidene-ethyl]-N-methyl-3-[4-(phenylmethyl)piperazin-1-yl]sulfonyl-benzamide::SMR001269406::cid_40197186 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114950&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 40197186 252664412 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239278 CNc1cncc(n1)-c1ccc(OC)c(OC)c1 InChI=1S/C13H15N3O2/c1-14-13-8-15-7-10(16-13)9-4-5-11(17-2)12(6-9)18-3/h4-8H,1-3H3,(H,14,16) IBANLFPWQFHDIU-UHFFFAOYSA-N 114951 6-(3,4-dimethoxyphenyl)-N-methyl-2-pyrazinamine::6-(3,4-dimethoxyphenyl)-N-methyl-pyrazin-2-amine::6-(3,4-dimethoxyphenyl)-N-methylpyrazin-2-amine::MLS003124383::SMR001285822::[6-(3,4-dimethoxyphenyl)pyrazin-2-yl]-methyl-amine::cid_49790206 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114951&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49790206 252664413 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239279 Fc1ccc(cc1F)-c1coc2c(cccc12)C(=O)NCc1cccs1 InChI=1S/C20H13F2NO2S/c21-17-7-6-12(9-18(17)22)16-11-25-19-14(16)4-1-5-15(19)20(24)23-10-13-3-2-8-26-13/h1-9,11H,10H2,(H,23,24) UHOLPYFINXJIEU-UHFFFAOYSA-N 114952 3-(3,4-difluorophenyl)-N-(2-thenyl)benzofuran-7-carboxamide::3-(3,4-difluorophenyl)-N-(thiophen-2-ylmethyl)-1-benzofuran-7-carboxamide::3-(3,4-difluorophenyl)-N-(thiophen-2-ylmethyl)-7-benzofurancarboxamide::3-[3,4-bis(fluoranyl)phenyl]-N-(thiophen-2-ylmethyl)-1-benzofuran-7-carboxamide::MLS003120477::SMR001289823::cid_49790913 Oxysterols receptor LXR-beta 67520 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114952&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49790913 252664414 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239280 CC(C)N(C)c1ncnc2n(cnc12)[C@H]1CN(Cc2cccnc2)C[C@@H](CO)O1 InChI=1S/C20H27N7O2/c1-14(2)25(3)19-18-20(23-12-22-19)27(13-24-18)17-10-26(9-16(11-28)29-17)8-15-5-4-6-21-7-15/h4-7,12-14,16-17,28H,8-11H2,1-3H3/t16-,17+/m0/s1 LUPCVFUBFQBCBE-DLBZAZTESA-N 114953 MLS003120851::SMR001273227::[(2S,6R)-6-[6-[isopropyl(methyl)amino]purin-9-yl]-4-(3-pyridylmethyl)morpholin-2-yl]methanol::[(2S,6R)-6-[6-[methyl(propan-2-yl)amino]-9-purinyl]-4-(3-pyridinylmethyl)-2-morpholinyl]methanol::[(2S,6R)-6-[6-[methyl(propan-2-yl)amino]purin-9-yl]-4-(pyridin-3-ylmethyl)morpholin-2-yl]methanol::cid_49792129 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114953&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49792129 252664415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239282 C(c1c(nc2c3ccccc3ccn12)-c1ccco1)c1ccccc1 InChI=1S/C22H16N2O/c1-2-7-16(8-3-1)15-19-21(20-11-6-14-25-20)23-22-18-10-5-4-9-17(18)12-13-24(19)22/h1-14H,15H2 XEXUOTIREUSVKK-UHFFFAOYSA-N 114955 2-(2-furanyl)-3-(phenylmethyl)imidazo[2,1-a]isoquinoline::2-(furan-2-yl)-3-(phenylmethyl)imidazo[2,1-a]isoquinoline::3-benzyl-2-(2-furyl)imidaz[2,1-a]isoquinoline::3-benzyl-2-(furan-2-yl)imidazo[2,1-a]isoquinoline::MLS003222295::SMR001906850::cid_51359022 Oxysterols receptor LXR-beta 67483 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114955&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 51359022 252664417 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239283 Fc1cccc(Cc2c(nc3c4ccccc4ccn23)-c2ccco2)c1 InChI=1S/C22H15FN2O/c23-17-7-3-5-15(13-17)14-19-21(20-9-4-12-26-20)24-22-18-8-2-1-6-16(18)10-11-25(19)22/h1-13H,14H2 QABSCKLJBHARTE-UHFFFAOYSA-N 114956 3-(3-fluorobenzyl)-2-(2-furyl)imidaz[2,1-a]isoquinoline::3-[(3-fluorophenyl)methyl]-2-(2-furanyl)imidazo[2,1-a]isoquinoline::3-[(3-fluorophenyl)methyl]-2-(furan-2-yl)imidazo[2,1-a]isoquinoline::MLS003222357::SMR001906912::cid_51359072 Oxysterols receptor LXR-beta 67500 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114956&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 51359072 252664418 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239284 Clc1cccc(c1)-c1nc2c3ccccc3ccn2c1Cc1ccsc1 InChI=1S/C22H15ClN2S/c23-18-6-3-5-17(13-18)21-20(12-15-9-11-26-14-15)25-10-8-16-4-1-2-7-19(16)22(25)24-21/h1-11,13-14H,12H2 LWTYTULBUUBCIW-UHFFFAOYSA-N 114957 2-(3-chlorophenyl)-3-(3-thenyl)imidaz[2,1-a]isoquinoline::2-(3-chlorophenyl)-3-(3-thiophenylmethyl)imidazo[2,1-a]isoquinoline::2-(3-chlorophenyl)-3-(thiophen-3-ylmethyl)imidazo[2,1-a]isoquinoline::MLS003231028::SMR001913593::cid_51360027 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114957&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 51360027 252664419 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239285 CCc1ccc2cc3-c4ccccc4C(=O)c3cc2n1 InChI=1S/C18H13NO/c1-2-12-8-7-11-9-15-13-5-3-4-6-14(13)18(20)16(15)10-17(11)19-12/h3-10H,2H2,1H3 JGGWFSZOUTVTAA-UHFFFAOYSA-N 114958 2-ethyl-10-indeno[1,2-g]quinolinone::2-ethylindeno[1,2-g]quinolin-10-one::MLS003269519::SMR001949485::cid_51361078 Oxysterols receptor LXR-beta 67462 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114958&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 51361078 252664420 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239286 Nc1nc(=O)n(cc1Cl)C1CC(O)C(CO)O1 InChI=1S/C9H12ClN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16) NGGRGTWYSXYVDK-UHFFFAOYSA-N 96305 4-amino-5-chloro-1-(4-hydroxy-5-methylol-tetrahydrofuran-2-yl)pyrimidin-2-one::4-amino-5-chloro-1-[4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone::4-amino-5-chloro-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one::4-azanyl-5-chloranyl-1-[5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]pyrimidin-2-one::CYTOCHLOR::MLS003389484::SMR002049134::cid_340558 Oxysterols receptor LXR-beta 67642 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96305&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 340558 164037549 ZINC17142057 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239287 C[C@H](N1C[C@@H](COCc2ccccc2)Oc2cc(ccc2S1(=O)=O)N1CCC[C@H]1C(N)=O)c1ccccc1 InChI=1S/C29H33N3O5S/c1-21(23-11-6-3-7-12-23)32-18-25(20-36-19-22-9-4-2-5-10-22)37-27-17-24(14-15-28(27)38(32,34)35)31-16-8-13-26(31)29(30)33/h2-7,9-12,14-15,17,21,25-26H,8,13,16,18-20H2,1H3,(H2,30,33)/t21-,25-,26-/m0/s1 VPLGRZIDUCEKGH-MZBJOSPHSA-N 114959 (2S)-1-[(4S)-1,1-bis(oxidanylidene)-2-[(1S)-1-phenylethyl]-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidine-2-carboxamide::(2S)-1-[(4S)-1,1-dioxo-2-[(1S)-1-phenylethyl]-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]-2-pyrrolidinecarboxamide::(2S)-1-[(4S)-1,1-dioxo-2-[(1S)-1-phenylethyl]-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidine-2-carboxamide::(2S)-1-[(4S)-4-(benzoxymethyl)-1,1-diketo-2-[(1S)-1-phenylethyl]-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidine-2-carboxamide::MLS003591849::SMR002253145::cid_53301614 Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114959&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53301614 252664421 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239288 CC(C)N1CCCc2c(C1)sc(NC(C)=O)c2-c1nc2ccccc2s1 InChI=1S/C20H23N3OS2/c1-12(2)23-10-6-7-14-17(11-23)26-19(21-13(3)24)18(14)20-22-15-8-4-5-9-16(15)25-20/h4-5,8-9,12H,6-7,10-11H2,1-3H3,(H,21,24) BBGBEKIWIWQGAB-UHFFFAOYSA-N 114960 CHEMBL1705313::MLS002607795::N-[3-(1,3-benzothiazol-2-yl)-7-isopropyl-4,5,6,8-tetrahydrothien[2,3-c]azepin-2-yl]acetamide;2,2,2-trifluoroacetic acid::N-[3-(1,3-benzothiazol-2-yl)-7-propan-2-yl-4,5,6,8-tetrahydrothieno[2,3-c]azepin-2-yl]acetamide;2,2,2-trifluoroacetic acid::N-[3-(1,3-benzothiazol-2-yl)-7-propan-2-yl-4,5,6,8-tetrahydrothieno[2,3-c]azepin-2-yl]ethanamide;2,2,2-tris(fluoranyl)ethanoic acid::SMR001522669::cid_53338854 Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114960&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46925889 252664422 CHEMBL1705313 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239289 CC(C)(C)NC(=O)C(c1cc2ccccc2o1)n1c(nc2ccccc12)-c1ccc(cc1)-c1ccccc1 InChI=1S/C33H29N3O2/c1-33(2,3)35-32(37)30(29-21-25-13-7-10-16-28(25)38-29)36-27-15-9-8-14-26(27)34-31(36)24-19-17-23(18-20-24)22-11-5-4-6-12-22/h4-21,30H,1-3H3,(H,35,37) TZZMXEBNOJXGSI-UHFFFAOYSA-N 114832 2-(1-benzofuran-2-yl)-N-tert-butyl-2-[2-(4-phenylphenyl)benzimidazol-1-yl]acetamide::2-(1-benzofuran-2-yl)-N-tert-butyl-2-[2-(4-phenylphenyl)benzimidazol-1-yl]ethanamide::2-(2-benzofuranyl)-N-tert-butyl-2-[2-(4-phenylphenyl)-1-benzimidazolyl]acetamide::2-(benzofuran-2-yl)-N-tert-butyl-2-[2-(4-phenylphenyl)benzimidazol-1-yl]acetamide::MLS003674655::SMR002353949::cid_53383229 Oxysterols receptor LXR-beta 67615 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114832&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53383229 252664303 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239290 COC(=O)[C@@]12Cc3c([C@H](N1CC=C2)c1ccc(OC)c(OC)c1)n(c1ccccc31)S(=O)(=O)c1ccc(C)cc1 InChI=1S/C31H30N2O6S/c1-20-10-13-22(14-11-20)40(35,36)33-25-9-6-5-8-23(25)24-19-31(30(34)39-4)16-7-17-32(31)28(29(24)33)21-12-15-26(37-2)27(18-21)38-3/h5-16,18,28H,17,19H2,1-4H3/t28-,31-/m1/s1 ZVSHKKZGSGXMFJ-GRKNLSHJSA-N 114961 (3aS,10R)-10-(3,4-dimethoxyphenyl)-9-(4-methylphenyl)sulfonyl-4,10-dihydro-1H-indolizino[6,7-b]indole-3a-carboxylic acid methyl ester::(3aS,10R)-10-(3,4-dimethoxyphenyl)-9-tosyl-4,10-dihydro-1H-pyrrolo[1,2-b]-carboline-3a-carboxylic acid methyl ester::MLS004342640::SMR003161308::cid_53491452::methyl (3aS,10R)-10-(3,4-dimethoxyphenyl)-9-(4-methylphenyl)sulfonyl-4,10-dihydro-1H-indolizino[6,7-b]indole-3a-carboxylate Oxysterols receptor LXR-beta 67517 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114961&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53491452 252664423 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238567 CN1\C(Sc2ccccc12)=C/C(=O)c1cccs1 InChI=1S/C14H11NOS2/c1-15-10-5-2-3-6-12(10)18-14(15)9-11(16)13-7-4-8-17-13/h2-9H,1H3/b14-9+ JMBZNSQGQKVUPF-NTEUORMPSA-N 49176 (2E)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-(2-thienyl)ethanone::(2E)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-thiophen-2-yl-ethanone::(2E)-2-(3-methyl-1,3-benzothiazol-2-ylidene)-1-thiophen-2-ylethanone::2-[3-Methyl-3H-benzothiazol-(2E)-ylidene]-1-thiophen-2-yl-ethanone::MLS000072102::SMR000009703::cid_1633229 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49176&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1633229 252629457 ZINC04746671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238568 N(c1nc(cs1)-c1cccs1)c1ccccn1 InChI=1S/C12H9N3S2/c1-2-6-13-11(5-1)15-12-14-9(8-17-12)10-4-3-7-16-10/h1-8H,(H,13,14,15) FHPWUMPMAJGLKK-UHFFFAOYSA-N 49177 2-pyridyl-[4-(2-thienyl)thiazol-2-yl]amine::MLS000030057::N-(2-pyridinyl)-4-thiophen-2-yl-2-thiazolamine::N-pyridin-2-yl-4-thiophen-2-yl-1,3-thiazol-2-amine::Pyridin-2-yl-(4-thiophen-2-yl-thiazol-2-yl)-amine::SMR000009411::cid_649291 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49177&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 649291 252629458 ZINC00295969 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238569 Cn1c(nc2cc3ccccc3cc12)-c1ccco1 InChI=1S/C16H12N2O/c1-18-14-10-12-6-3-2-5-11(12)9-13(14)17-16(18)15-7-4-8-19-15/h2-10H,1H3 JBKWIIRGZGWOGD-UHFFFAOYSA-N 38855 2-(2-furanyl)-3-methylbenzo[f]benzimidazole::2-(2-furyl)-3-methyl-benzo[f]benzimidazole::2-(furan-2-yl)-3-methyl-benzo[f]benzimidazole::2-(furan-2-yl)-3-methylbenzo[f]benzimidazole::2-Furan-2-yl-1-methyl-1H-naphtho[2,3-d]imidazole::MLS000034730::SMR000014331::cid_649492 Oxysterols receptor LXR-beta 67527 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38855&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 649492 252619758 ZINC00807829 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238570 Clc1cccc(c1)-c1nc(no1)-c1ccccn1 InChI=1S/C13H8ClN3O/c14-10-5-3-4-9(8-10)13-16-12(17-18-13)11-6-1-2-7-15-11/h1-8H IMLLSKDXLVDFRH-UHFFFAOYSA-N 38857 2-[5-(3-Chloro-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine::5-(3-chlorophenyl)-3-(2-pyridinyl)-1,2,4-oxadiazole::5-(3-chlorophenyl)-3-(2-pyridyl)-1,2,4-oxadiazole::5-(3-chlorophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole::MLS000075853::SMR000013634::cid_650707 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38857&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 650707 252619760 ZINC00199359 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238571 Cc1ccnc(NC(=O)Nc2cccc(F)c2)c1 InChI=1S/C13H12FN3O/c1-9-5-6-15-12(7-9)17-13(18)16-11-4-2-3-10(14)8-11/h2-8H,1H3,(H2,15,16,17,18) BPECMASLXQFQDL-UHFFFAOYSA-N 49185 1-(3-Fluoro-phenyl)-3-(4-methyl-pyridin-2-yl)-urea::1-(3-fluorophenyl)-3-(4-methyl-2-pyridinyl)urea::1-(3-fluorophenyl)-3-(4-methyl-2-pyridyl)urea::1-(3-fluorophenyl)-3-(4-methylpyridin-2-yl)urea::MLS000034324::SMR000010882::cid_653592 Oxysterols receptor LXR-beta 67516 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49185&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 653592 252629466 ZINC00319195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238572 O=C1C(C(=O)c2ccccc12)c1ccc2ccccc2n1 InChI=1S/C18H11NO2/c20-17-12-6-2-3-7-13(12)18(21)16(17)15-10-9-11-5-1-4-8-14(11)19-15/h1-10,16H IZMJMCDDWKSTTK-UHFFFAOYSA-N 32227 2-(1H-quinolin-2-ylidene)indane-1,3-quinone::2-(1H-quinolin-2-ylidene)indene-1,3-dione::2-(2-quinolyl)indane-1,3-quinone::cid_5355280 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32227&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6731 252615674 ZINC03848530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238573 COc1ccc2c(c1)occ(-c1nc(C)cs1)c2=O InChI=1S/C14H11NO3S/c1-8-7-19-14(15-8)11-6-18-12-5-9(17-2)3-4-10(12)13(11)16/h3-7H,1-2H3 YNXUOZQWIMSWGH-UHFFFAOYSA-N 49196 7-methoxy-3-(4-methyl-1,3-thiazol-2-yl)chromen-4-one::7-methoxy-3-(4-methyl-2-thiazolyl)-1-benzopyran-4-one::7-methoxy-3-(4-methylthiazol-2-yl)chromone::MLS000038399::SMR000039004::cid_658167 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49196&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 658167 252629477 ZINC04338829 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238574 O=C(c1cccs1)c1ccc(s1)-c1cccs1 InChI=1S/C13H8OS3/c14-13(11-4-2-8-16-11)12-6-5-10(17-12)9-3-1-7-15-9/h1-8H ZZXVQKQWUPAJOI-UHFFFAOYSA-N 49198 2-thienyl-[5-(2-thienyl)-2-thienyl]methanone::MLS000039108::SMR000040256::cid_659191::thiophen-2-yl-(5-thiophen-2-yl-2-thiophenyl)methanone::thiophen-2-yl-(5-thiophen-2-ylthiophen-2-yl)methanone Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49198&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 659191 252629479 ZINC00506942 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238575 Nc1c(Br)cc2oc(nc2c1Br)-c1ccccc1 InChI=1S/C13H8Br2N2O/c14-8-6-9-12(10(15)11(8)16)17-13(18-9)7-4-2-1-3-5-7/h1-6H,16H2 YXHPZBKRNNWMLV-UHFFFAOYSA-N 114715 (4,6-dibromo-2-phenyl-1,3-benzoxazol-5-yl)amine::4,6-bis(bromanyl)-2-phenyl-1,3-benzoxazol-5-amine::4,6-dibromo-2-phenyl-1,3-benzoxazol-5-amine::MLS000036498::SMR000035928::cid_661662 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114715&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 661662 252664196 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238576 Cc1ccsc1C(=O)OCc1csc(n1)-c1ccccc1 InChI=1S/C16H13NO2S2/c1-11-7-8-20-14(11)16(18)19-9-13-10-21-15(17-13)12-5-3-2-4-6-12/h2-8,10H,9H2,1H3 LZOCRTGDFVXVLX-UHFFFAOYSA-N 49211 (2-phenyl-1,3-thiazol-4-yl)methyl 3-methylthiophene-2-carboxylate::3-methyl-2-thiophenecarboxylic acid (2-phenyl-4-thiazolyl)methyl ester::3-methylthiophene-2-carboxylic acid (2-phenylthiazol-4-yl)methyl ester::MLS000096549::SMR000062394::cid_2997521 Oxysterols receptor LXR-beta 67532 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49211&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2997521 252629492 ZINC04195455 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238577 Nn1c(nc2sc3CCCCc3c2c1=O)-c1cccs1 InChI=1S/C14H13N3OS2/c15-17-12(10-6-3-7-19-10)16-13-11(14(17)18)8-4-1-2-5-9(8)20-13/h3,6-7H,1-2,4-5,15H2 PUOFENAWFXNNIH-UHFFFAOYSA-N 68461 3-amino-2-(2-thienyl)-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]pyrimidin-4-one::3-amino-2-thiophen-2-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one::3-azanyl-2-thiophen-2-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one::MLS000054555::SMR000061127::cid_943152 Oxysterols receptor LXR-beta 67530 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68461&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 943152 252646637 ZINC00540559 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238578 Cc1cc(C(=O)Cn2nnc3ccccc3c2=O)c(C)n1Cc1cccs1 InChI=1S/C20H18N4O2S/c1-13-10-17(14(2)23(13)11-15-6-5-9-27-15)19(25)12-24-20(26)16-7-3-4-8-18(16)21-22-24/h3-10H,11-12H2,1-2H3 ISGSUMIEOVJPHD-UHFFFAOYSA-N 114716 3-[2-[2,5-dimethyl-1-(2-thenyl)pyrrol-3-yl]-2-keto-ethyl]-1,2,3-benzotriazin-4-one::3-[2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)-3-pyrrolyl]-2-oxoethyl]-1,2,3-benzotriazin-4-one::3-[2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-yl]-2-oxidanylidene-ethyl]-1,2,3-benzotriazin-4-one::3-[2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-yl]-2-oxoethyl]-1,2,3-benzotriazin-4-one::MLS000081780::SMR000063454::cid_2109648 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114716&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2109648 252664197 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238579 Cn1cccc1C(=O)OCc1csc(n1)-c1ccccc1 InChI=1S/C16H14N2O2S/c1-18-9-5-8-14(18)16(19)20-10-13-11-21-15(17-13)12-6-3-2-4-7-12/h2-9,11H,10H2,1H3 SWGLEZWLVBJBAG-UHFFFAOYSA-N 39548 (2-phenyl-1,3-thiazol-4-yl)methyl 1-methylpyrrole-2-carboxylate::1-methyl-2-pyrrolecarboxylic acid (2-phenyl-4-thiazolyl)methyl ester::1-methylpyrrole-2-carboxylic acid (2-phenylthiazol-4-yl)methyl ester::MLS000058002::SMR000063048::cid_2091642 Oxysterols receptor LXR-beta 67534 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39548&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2091642 252620439 ZINC02629255 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238580 COc1ccc(cc1)-c1cc(=O)c2ccccc2s1 InChI=1S/C16H12O2S/c1-18-12-8-6-11(7-9-12)16-10-14(17)13-4-2-3-5-15(13)19-16/h2-10H,1H3 ZLYYLYIZXHSKBL-UHFFFAOYSA-N 49223 2-(4-methoxyphenyl)-1-benzothiopyran-4-one::2-(4-methoxyphenyl)thiochromen-4-one::MLS000055679::SMR000060696::cid_2324877 Oxysterols receptor LXR-beta 67541 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49223&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2324877 252629504 ZINC03199812 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238581 Cc1ccc(cc1)N=C1Nc2ccccc2CS1 InChI=1S/C15H14N2S/c1-11-6-8-13(9-7-11)16-15-17-14-5-3-2-4-12(14)10-18-15/h2-9H,10H2,1H3,(H,16,17) WAIDGCCWBIIWOI-UHFFFAOYSA-N 39099 4H-3,1-benzothiazin-2-yl(p-tolyl)amine::MLS000054598::N-(4-methylphenyl)-4H-3,1-benzothiazin-2-amine::SMR000061366::cid_2999727 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39099&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2999727 252619998 ZINC03885636 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238582 OP1(=O)C=C(OC(=C1)c1ccccc1)c1ccccc1 InChI=1S/C16H13O3P/c17-20(18)11-15(13-7-3-1-4-8-13)19-16(12-20)14-9-5-2-6-10-14/h1-12H,(H,17,18) GTQWDLLIYQXLFL-UHFFFAOYSA-N 114717 4-hydroxy-2,6-diphenyl-1,4-oxaphosphinine 4-oxide::4-hydroxy-2,6-diphenyl-1,4-oxaphosphorin 4-oxide::4-oxidanyl-2,6-diphenyl-1,4-oxaphosphinine 4-oxide::MLS000097831::SMR000059942::cid_2322533 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114717&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2322533 252664198 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238583 Oc1ccccc1NC=C1C(=O)c2ccccc2C1=O InChI=1S/C16H11NO3/c18-14-8-4-3-7-13(14)17-9-12-15(19)10-5-1-2-6-11(10)16(12)20/h1-9,17-18H GRCNTRGUKRFBGH-UHFFFAOYSA-N 42723 2-[(2-hydroxyanilino)methylene]indane-1,3-quinone::2-[(2-hydroxyanilino)methylidene]indene-1,3-dione::2-[[(2-hydroxyphenyl)amino]methylidene]indene-1,3-dione::2-{[(2-hydroxyphenyl)amino]methylene}-1H-indene-1,3(2H)-dione::MLS000090106::SMR000024724::cid_3241704 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42723&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3241704 252623415 ZINC13749986 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238584 O=C1C(C(=O)c2ccccc12)c1nccc2ccccc12 InChI=1S/C18H11NO2/c20-17-13-7-3-4-8-14(13)18(21)15(17)16-12-6-2-1-5-11(12)9-10-19-16/h1-10,15H KXIAYOHGMQBMRT-UHFFFAOYSA-N 38985 2-(1-isoquinolinyl)indene-1,3-dione::2-(1-isoquinolyl)indane-1,3-quinone::2-isoquinolin-1-yl-1H-indene-1,3(2H)-dione::2-isoquinolin-1-ylindene-1,3-dione::MLS000085507::SMR000020442::cid_3243985 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38985&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3243985 252619885 ZINC03908918 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238585 c1ccc(nc1)-c1noc(n1)-c1cccc2ccccc12 InChI=1S/C17H11N3O/c1-2-8-13-12(6-1)7-5-9-14(13)17-19-16(20-21-17)15-10-3-4-11-18-15/h1-11H YGUDIHOQAIXIFH-UHFFFAOYSA-N 114718 2-[5-(1-naphthyl)-1,2,4-oxadiazol-3-yl]pyridine::5-(1-naphthalenyl)-3-(2-pyridinyl)-1,2,4-oxadiazole::5-(1-naphthyl)-3-(2-pyridyl)-1,2,4-oxadiazole::5-naphthalen-1-yl-3-pyridin-2-yl-1,2,4-oxadiazole::MLS000099078::SMR000070081::cid_757874 Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114718&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 757874 252664199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238586 Fc1ccc(cc1)-c1nc2-c3ccccc3Cn2n1 InChI=1S/C15H10FN3/c16-12-7-5-10(6-8-12)14-17-15-13-4-2-1-3-11(13)9-19(15)18-14/h1-8H,9H2 OTMSGGRGWSIHPW-UHFFFAOYSA-N 49255 2-(4-fluorophenyl)-5H-[1,2,4]triazol[5,1-a]isoindole::2-(4-fluorophenyl)-5H-[1,2,4]triazolo[5,1-a]isoindole::MLS000066641::SMR000082547::cid_1236969 Oxysterols receptor LXR-beta 67554 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49255&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1236969 252629536 ZINC01020521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238587 COc1cccc(c1)-c1nc(no1)-c1ccccc1 InChI=1S/C15H12N2O2/c1-18-13-9-5-8-12(10-13)15-16-14(17-19-15)11-6-3-2-4-7-11/h2-10H,1H3 FXBISMLJWSAZKK-UHFFFAOYSA-N 49259 5-(3-methoxyphenyl)-3-phenyl-1,2,4-oxadiazole::MLS000099081::SMR000070084::cid_619837 Oxysterols receptor LXR-beta 67561 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49259&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 619837 252629540 ZINC00290328 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238588 Fc1ccc(cc1Cl)N=CCC(=O)c1ccco1 InChI=1S/C13H9ClFNO2/c14-10-8-9(3-4-11(10)15)16-6-5-12(17)13-2-1-7-18-13/h1-4,6-8H,5H2 CKCMBCDEUSPVPG-UHFFFAOYSA-N 93722 (E)-3-(3-chloro-4-fluoro-anilino)-1-(2-furyl)prop-2-en-1-one::(E)-3-(3-chloro-4-fluoroanilino)-1-(2-furanyl)-2-propen-1-one::(E)-3-(3-chloro-4-fluoroanilino)-1-(furan-2-yl)prop-2-en-1-one::(E)-3-[(3-chloranyl-4-fluoranyl-phenyl)amino]-1-(furan-2-yl)prop-2-en-1-one::3-[(3-chloro-4-fluorophenyl)amino]-1-(2-furyl)-2-propen-1-one::MLS000049015::SMR000074262::cid_2196534 Oxysterols receptor LXR-beta 67538 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93722&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899512 164034966 ZINC07991393 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238589 COc1ccc(cc1)-c1cn2c3CCCCc3sc2n1 InChI=1S/C16H16N2OS/c1-19-12-8-6-11(7-9-12)13-10-18-14-4-2-3-5-15(14)20-16(18)17-13/h6-10H,2-5H2,1H3 RQGHLASMYPXWEW-UHFFFAOYSA-N 49272 2-(4-methoxyphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole::MLS000087973::SMR000072169::cid_848469 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49272&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 848469 252629553 ZINC00382808 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238590 c1ccc2oc(nc2c1)-c1ccc2ccccc2n1 InChI=1S/C16H10N2O/c1-2-6-12-11(5-1)9-10-14(17-12)16-18-13-7-3-4-8-15(13)19-16/h1-10H LEYACHSFIUEDPZ-UHFFFAOYSA-N 39018 2-(1,3-benzoxazol-2-yl)quinoline::2-(2-quinolinyl)-1,3-benzoxazole::2-(2-quinolyl)-1,3-benzoxazole::2-quinolin-2-yl-1,3-benzoxazole::MLS000059165::SMR000069536::cid_723043 Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 723043 252619917 ZINC00127681 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238591 CCOC(=O)c1c(C)nc(nc1N)-c1ccccc1 InChI=1S/C14H15N3O2/c1-3-19-14(18)11-9(2)16-13(17-12(11)15)10-7-5-4-6-8-10/h4-8H,3H2,1-2H3,(H2,15,16,17) PEJSJBWYFBHJLY-UHFFFAOYSA-N 114719 4-amino-6-methyl-2-phenyl-5-pyrimidinecarboxylic acid ethyl ester::4-amino-6-methyl-2-phenyl-pyrimidine-5-carboxylic acid ethyl ester::MLS000060918::SMR000069146::cid_611239::ethyl 4-amino-6-methyl-2-phenyl-5-pyrimidinecarboxylate::ethyl 4-amino-6-methyl-2-phenylpyrimidine-5-carboxylate::ethyl 4-azanyl-6-methyl-2-phenyl-pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 67506 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114719&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 611239 252664200 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238592 Cc1ccc(cc1)-c1nnc(Nc2ccccc2)[nH]1 InChI=1S/C15H14N4/c1-11-7-9-12(10-8-11)14-17-15(19-18-14)16-13-5-3-2-4-6-13/h2-10H,1H3,(H2,16,17,18,19) INDCVHFFYIEZRU-UHFFFAOYSA-N 49285 5-(4-methylphenyl)-N-phenyl-1H-1,2,4-triazol-3-amine::MLS000097050::SMR000075700::cid_2951125::phenyl-[5-(p-tolyl)-1H-1,2,4-triazol-3-yl]amine Oxysterols receptor LXR-beta 67536 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49285&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2951125 252629566 ZINC06492163 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238593 Fc1ccccc1-c1nc(no1)-c1ccccc1 InChI=1S/C14H9FN2O/c15-12-9-5-4-8-11(12)14-16-13(17-18-14)10-6-2-1-3-7-10/h1-9H KHDXKUPLQGEWMA-UHFFFAOYSA-N 49298 5-(2-fluorophenyl)-3-phenyl-1,2,4-oxadiazole::MLS000062114::SMR000070388::cid_2876651 Oxysterols receptor LXR-beta 67529 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49298&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2876651 252629579 ZINC04008265 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238594 COc1ccccc1-c1nc(no1)-c1cccc(C)c1 InChI=1S/C16H14N2O2/c1-11-6-5-7-12(10-11)15-17-16(20-18-15)13-8-3-4-9-14(13)19-2/h3-10H,1-2H3 OQWLLCHAISGPKT-UHFFFAOYSA-N 37142 5-(2-methoxyphenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole::5-(2-methoxyphenyl)-3-(m-tolyl)-1,2,4-oxadiazole::MLS000066741::SMR000082761::cid_2243275 Oxysterols receptor LXR-beta 67531 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37142&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2243275 252618113 ZINC02890892 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 297651 CC(C)C1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C19H20F3N5O2S/c1-11(2)16-17-24-13-5-4-12(30(3,28)29)10-14(13)26(17)8-9-27(16)18-23-7-6-15(25-18)19(20,21)22/h4-7,10-11,16H,8-9H2,1-3H3 SEQLXXRHDQNPMX-UHFFFAOYSA-N 155256 US9006244, E1 Oxysterols receptor LXR-beta 256 US Patent 10.7270/Q2X92911 aid1801179 US9006244 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155256&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89815984 253658258 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 297652 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H22F3N5O3S/c1-11(2)17-18-25-13-8-12(10-29)15(32(3,30)31)9-14(13)27(18)6-7-28(17)19-24-5-4-16(26-19)20(21,22)23/h4-5,8-9,11,17,29H,6-7,10H2,1-3H3/t17-/m1/s1 CABUZECPUSGGRX-QGZVFWFLSA-N 155257 US9006244, E2a::US9814715, Example 2, isomer 1 Oxysterols receptor LXR-beta 20 US Patent 10.7270/Q2X92911 aid1801179 US9006244 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155257&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735263 253658259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 297653 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H22F3N5O3S/c1-11(2)17-18-25-13-8-12(10-29)15(32(3,30)31)9-14(13)27(18)6-7-28(17)19-24-5-4-16(26-19)20(21,22)23/h4-5,8-9,11,17,29H,6-7,10H2,1-3H3/t17-/m0/s1 CABUZECPUSGGRX-KRWDZBQOSA-N 155258 US9006244, E2b::US9814715, Example 2, isomer 2 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2X92911 aid1801179 US9006244 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155258&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735264 253658260 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 297654 CC(C)[C@H]1N(CCn2c1cc1ccc(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H21F3N4O2S/c1-12(2)18-16-10-13-4-5-14(30(3,28)29)11-15(13)26(16)8-9-27(18)19-24-7-6-17(25-19)20(21,22)23/h4-7,10-12,18H,8-9H2,1-3H3/t18-/m1/s1 HKNRVRUCDFTKQI-GOSISDBHSA-N 155259 US9006244, E3a::US9814715, Example 3, isomer 1 Oxysterols receptor LXR-beta 27 US Patent 10.7270/Q2X92911 aid1801179 US9006244 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155259&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735265 253658261 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 297655 CC(C)[C@@H]1N(CCn2c1cc1ccc(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H21F3N4O2S/c1-12(2)18-16-10-13-4-5-14(30(3,28)29)11-15(13)26(16)8-9-27(18)19-24-7-6-17(25-19)20(21,22)23/h4-7,10-12,18H,8-9H2,1-3H3/t18-/m0/s1 HKNRVRUCDFTKQI-SFHVURJKSA-N 155260 US9006244, E3b::US9814715, Example 3, isomer 2 Oxysterols receptor LXR-beta 1750 US Patent 10.7270/Q2X92911 aid1801179 US9006244 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155260&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89827883 253658262 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 297656 CC(C)[C@H]1N(CCn2c1cc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C21H23F3N4O3S/c1-12(2)19-16-9-13-8-14(11-29)17(32(3,30)31)10-15(13)27(16)6-7-28(19)20-25-5-4-18(26-20)21(22,23)24/h4-5,8-10,12,19,29H,6-7,11H2,1-3H3/t19-/m1/s1 XRWDAQASJVEARP-LJQANCHMSA-N 155261 US9006244, E4a::US9814715, Example 4, isomer 1 Oxysterols receptor LXR-beta 4 US Patent 10.7270/Q2X92911 aid1801179 US9006244 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155261&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71722107 253658263 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 297657 CC(C)[C@@H]1N(CCn2c1cc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C21H23F3N4O3S/c1-12(2)19-16-9-13-8-14(11-29)17(32(3,30)31)10-15(13)27(16)6-7-28(19)20-25-5-4-18(26-20)21(22,23)24/h4-5,8-10,12,19,29H,6-7,11H2,1-3H3/t19-/m0/s1 XRWDAQASJVEARP-IBGZPJMESA-N 155262 US9006244, E4b::US9814715, Example 4, isomer 2 Oxysterols receptor LXR-beta 846 US Patent 10.7270/Q2X92911 aid1801179 US9006244 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155262&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735262 253658264 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312034 CC(C)C1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)=O)c(n1)C(F)(F)F InChI=1S/C21H22F3N5O3S/c1-11(2)17-19-26-15-6-5-13(33(4,31)32)9-16(15)28(19)7-8-29(17)20-25-10-14(12(3)30)18(27-20)21(22,23)24/h5-6,9-11,17H,7-8H2,1-4H3 UVRFHLLVIGMMMM-UHFFFAOYSA-N 168072 US9073931, E1 Oxysterols receptor LXR-beta 191 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735986 312525486 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312035 CC(C)C1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C22H26F3N5O3S/c1-12(2)17-19-27-15-7-6-13(34(5,32)33)10-16(15)29(19)8-9-30(17)20-26-11-14(21(3,4)31)18(28-20)22(23,24)25/h6-7,10-12,17,31H,8-9H2,1-5H3 LOFRRPNYSLDHRM-UHFFFAOYSA-N 168073 US9073931, E2 Oxysterols receptor LXR-beta 176 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735987 312525487 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312036 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3ccc(cc23)S(C)(=O)=O)C1C(C)C InChI=1S/C22H24F3N5O4S/c1-5-34-20(31)14-11-26-21(28-18(14)22(23,24)25)30-9-8-29-16-10-13(35(4,32)33)6-7-15(16)27-19(29)17(30)12(2)3/h6-7,10-12,17H,5,8-9H2,1-4H3 VWVWWPZPLJBDBN-UHFFFAOYSA-N 168074 US9073931, E3 Oxysterols receptor LXR-beta 1160 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735988 312525488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312037 CC(C)C1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C20H22F3N5O3S/c1-11(2)16-18-25-14-5-4-13(32(3,30)31)8-15(14)27(18)6-7-28(16)19-24-9-12(10-29)17(26-19)20(21,22)23/h4-5,8-9,11,16,29H,6-7,10H2,1-3H3 MWSOCMMZIFOCRI-UHFFFAOYSA-N 168075 US9073931, E4 Oxysterols receptor LXR-beta 137 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735989 312525489 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312038 CC(C)C1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(N)=O)c(n1)C(F)(F)F InChI=1S/C20H21F3N6O3S/c1-10(2)15-18-26-13-5-4-11(33(3,31)32)8-14(13)28(18)6-7-29(15)19-25-9-12(17(24)30)16(27-19)20(21,22)23/h4-5,8-10,15H,6-7H2,1-3H3,(H2,24,30) GOMMIXQAFBFDBV-UHFFFAOYSA-N 168076 US9073931, E5 Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736147 312525490 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312039 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)=O)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-11(2)18-20-27-15-7-13(10-31)17(35(4,33)34)8-16(15)29(20)5-6-30(18)21-26-9-14(12(3)32)19(28-21)22(23,24)25/h7-9,11,18,31H,5-6,10H2,1-4H3/t18-/m1/s1 LWXOLPDIDYBJQJ-GOSISDBHSA-N 168077 US9073931, E6a Oxysterols receptor LXR-beta 14 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89816060 312525491 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312040 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)=O)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-11(2)18-20-27-15-7-13(10-31)17(35(4,33)34)8-16(15)29(20)5-6-30(18)21-26-9-14(12(3)32)19(28-21)22(23,24)25/h7-9,11,18,31H,5-6,10H2,1-4H3/t18-/m0/s1 LWXOLPDIDYBJQJ-SFHVURJKSA-N 168078 US9073931, E6b Oxysterols receptor LXR-beta 1190 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89815950 312525492 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312041 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C23H28F3N5O4S/c1-12(2)18-20-28-15-8-13(11-32)17(36(5,34)35)9-16(15)30(20)6-7-31(18)21-27-10-14(22(3,4)33)19(29-21)23(24,25)26/h8-10,12,18,32-33H,6-7,11H2,1-5H3/t18-/m1/s1 IUMMDSSCERZSTJ-GOSISDBHSA-N 168079 US9073931, E27a::US9073931, E7a Oxysterols receptor LXR-beta 14 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736150 312525493 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312042 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C23H28F3N5O4S/c1-12(2)18-20-28-15-8-13(11-32)17(36(5,34)35)9-16(15)30(20)6-7-31(18)21-27-10-14(22(3,4)33)19(29-21)23(24,25)26/h8-10,12,18,32-33H,6-7,11H2,1-5H3/t18-/m0/s1 IUMMDSSCERZSTJ-SFHVURJKSA-N 168080 US9073931, E27b::US9073931, E7b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736151 312525494 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312043 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C22H26F3N5O4S/c1-11(2)18-20-27-15-7-13(10-31)17(35(4,33)34)8-16(15)29(20)5-6-30(18)21-26-9-14(12(3)32)19(28-21)22(23,24)25/h7-9,11-12,18,31-32H,5-6,10H2,1-4H3/t12?,18-/m0/s1 WAZXSGZGKNWHSO-ZJFPTPTDSA-N 168081 US9073931, E8a::US9073931, E8d Oxysterols receptor LXR-beta 1650 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89828104 312525495 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312044 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C22H26F3N5O4S/c1-11(2)18-20-27-15-7-13(10-31)17(35(4,33)34)8-16(15)29(20)5-6-30(18)21-26-9-14(12(3)32)19(28-21)22(23,24)25/h7-9,11-12,18,31-32H,5-6,10H2,1-4H3/t12?,18-/m1/s1 WAZXSGZGKNWHSO-VMHBGOFLSA-N 168082 US9073931, E8b::US9073931, E8c Oxysterols receptor LXR-beta 13 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736312 312525496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312045 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C22H26F3N5O4S/c1-11(2)18-20-27-15-7-13(10-31)17(35(4,33)34)8-16(15)29(20)5-6-30(18)21-26-9-14(12(3)32)19(28-21)22(23,24)25/h7-9,11-12,18,31-32H,5-6,10H2,1-4H3/t12?,18-/m1/s1 WAZXSGZGKNWHSO-VMHBGOFLSA-N 168082 US9073931, E8b::US9073931, E8c Oxysterols receptor LXR-beta 9 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736312 312525496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312046 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C22H26F3N5O4S/c1-11(2)18-20-27-15-7-13(10-31)17(35(4,33)34)8-16(15)29(20)5-6-30(18)21-26-9-14(12(3)32)19(28-21)22(23,24)25/h7-9,11-12,18,31-32H,5-6,10H2,1-4H3/t12?,18-/m0/s1 WAZXSGZGKNWHSO-ZJFPTPTDSA-N 168081 US9073931, E8a::US9073931, E8d Oxysterols receptor LXR-beta 1330 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89828104 312525495 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312047 CCC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C23H26F3N5O4S/c1-5-17(33)14-10-27-22(29-20(14)23(24,25)26)31-7-6-30-16-9-18(36(4,34)35)13(11-32)8-15(16)28-21(30)19(31)12(2)3/h8-10,12,19,32H,5-7,11H2,1-4H3/t19-/m1/s1 HLMVLEINLZPXPH-LJQANCHMSA-N 168085 US9073931, E9a Oxysterols receptor LXR-beta 17 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168085&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736313 312525497 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312048 CCC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@@H]1C(C)C InChI=1S/C23H26F3N5O4S/c1-5-17(33)14-10-27-22(29-20(14)23(24,25)26)31-7-6-30-16-9-18(36(4,34)35)13(11-32)8-15(16)28-21(30)19(31)12(2)3/h8-10,12,19,32H,5-7,11H2,1-4H3/t19-/m0/s1 HLMVLEINLZPXPH-IBGZPJMESA-N 168086 US9073931, E9b Oxysterols receptor LXR-beta 1360 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168086&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736314 312525498 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312049 CCC(O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@@H]1C(C)C InChI=1S/C23H28F3N5O4S/c1-5-17(33)14-10-27-22(29-20(14)23(24,25)26)31-7-6-30-16-9-18(36(4,34)35)13(11-32)8-15(16)28-21(30)19(31)12(2)3/h8-10,12,17,19,32-33H,5-7,11H2,1-4H3/t17?,19-/m0/s1 OEALQQJYLLGJFL-NNBQYGFHSA-N 168087 US9073931, E10a::US9073931, E10d Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168087&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736315 312525499 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312050 CCC(O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C23H28F3N5O4S/c1-5-17(33)14-10-27-22(29-20(14)23(24,25)26)31-7-6-30-16-9-18(36(4,34)35)13(11-32)8-15(16)28-21(30)19(31)12(2)3/h8-10,12,17,19,32-33H,5-7,11H2,1-4H3/t17?,19-/m1/s1 OEALQQJYLLGJFL-WHCXFUJUSA-N 168088 US9073931, E10b::US9073931, E10c Oxysterols receptor LXR-beta 7 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168088&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71722093 312525500 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312051 CCC(O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C23H28F3N5O4S/c1-5-17(33)14-10-27-22(29-20(14)23(24,25)26)31-7-6-30-16-9-18(36(4,34)35)13(11-32)8-15(16)28-21(30)19(31)12(2)3/h8-10,12,17,19,32-33H,5-7,11H2,1-4H3/t17?,19-/m1/s1 OEALQQJYLLGJFL-WHCXFUJUSA-N 168088 US9073931, E10b::US9073931, E10c Oxysterols receptor LXR-beta 7 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168088&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71722093 312525500 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312052 CCC(O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@@H]1C(C)C InChI=1S/C23H28F3N5O4S/c1-5-17(33)14-10-27-22(29-20(14)23(24,25)26)31-7-6-30-16-9-18(36(4,34)35)13(11-32)8-15(16)28-21(30)19(31)12(2)3/h8-10,12,17,19,32-33H,5-7,11H2,1-4H3/t17?,19-/m0/s1 OEALQQJYLLGJFL-NNBQYGFHSA-N 168087 US9073931, E10a::US9073931, E10d Oxysterols receptor LXR-beta 1940 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168087&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736315 312525499 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312053 CCCC(O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C24H30F3N5O4S/c1-5-6-18(34)15-11-28-23(30-21(15)24(25,26)27)32-8-7-31-17-10-19(37(4,35)36)14(12-33)9-16(17)29-22(31)20(32)13(2)3/h9-11,13,18,20,33-34H,5-8,12H2,1-4H3/t18?,20-/m1/s1 WZDFAJOVHXXHKS-ROPPNANJSA-N 168091 US9073931, E11a::US9073931, E11b Oxysterols receptor LXR-beta 14 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168091&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736316 312525501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312054 CCCC(O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C24H30F3N5O4S/c1-5-6-18(34)15-11-28-23(30-21(15)24(25,26)27)32-8-7-31-17-10-19(37(4,35)36)14(12-33)9-16(17)29-22(31)20(32)13(2)3/h9-11,13,18,20,33-34H,5-8,12H2,1-4H3/t18?,20-/m1/s1 WZDFAJOVHXXHKS-ROPPNANJSA-N 168091 US9073931, E11a::US9073931, E11b Oxysterols receptor LXR-beta 23 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168091&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736316 312525501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312055 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C23H26F3N5O5S/c1-5-36-21(33)14-10-27-22(29-19(14)23(24,25)26)31-7-6-30-16-9-17(37(4,34)35)13(11-32)8-15(16)28-20(30)18(31)12(2)3/h8-10,12,18,32H,5-7,11H2,1-4H3/t18-/m1/s1 YXXFEOBGLYBWLG-GOSISDBHSA-N 168093 US9073931, E12 Oxysterols receptor LXR-beta 6 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168093&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736478 312525502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312056 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C21H24F3N5O4S/c1-11(2)17-19-26-14-6-12(9-30)16(34(3,32)33)7-15(14)28(19)4-5-29(17)20-25-8-13(10-31)18(27-20)21(22,23)24/h6-8,11,17,30-31H,4-5,9-10H2,1-3H3/t17-/m1/s1 QVTVCGSKZXEEPI-QGZVFWFLSA-N 168094 US9073931, E13a Oxysterols receptor LXR-beta 17 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168094&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736479 312525503 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312057 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C21H24F3N5O4S/c1-11(2)17-19-26-14-6-12(9-30)16(34(3,32)33)7-15(14)28(19)4-5-29(17)20-25-8-13(10-31)18(27-20)21(22,23)24/h6-8,11,17,30-31H,4-5,9-10H2,1-3H3/t17-/m0/s1 QVTVCGSKZXEEPI-KRWDZBQOSA-N 168095 US9073931, E13b Oxysterols receptor LXR-beta 1040 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168095&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736480 312525504 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312058 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(O)=O)c(n1)C(F)(F)F InChI=1S/C21H22F3N5O5S/c1-10(2)16-18-26-13-6-11(9-30)15(35(3,33)34)7-14(13)28(18)4-5-29(16)20-25-8-12(19(31)32)17(27-20)21(22,23)24/h6-8,10,16,30H,4-5,9H2,1-3H3,(H,31,32)/t16-/m1/s1 VOOWYLAUROXLNZ-MRXNPFEDSA-N 168096 US9073931, E14a Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168096&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736481 312525505 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312059 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(O)=O)c(n1)C(F)(F)F InChI=1S/C21H22F3N5O5S/c1-10(2)16-18-26-13-6-11(9-30)15(35(3,33)34)7-14(13)28(18)4-5-29(16)20-25-8-12(19(31)32)17(27-20)21(22,23)24/h6-8,10,16,30H,4-5,9H2,1-3H3,(H,31,32)/t16-/m0/s1 VOOWYLAUROXLNZ-INIZCTEOSA-N 168097 US9073931, E14b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736482 312525506 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312060 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(N)=O)c(n1)C(F)(F)F InChI=1S/C21H23F3N6O4S/c1-10(2)16-19-27-13-6-11(9-31)15(35(3,33)34)7-14(13)29(19)4-5-30(16)20-26-8-12(18(25)32)17(28-20)21(22,23)24/h6-8,10,16,31H,4-5,9H2,1-3H3,(H2,25,32)/t16-/m1/s1 XZVKGPBWXMHCFG-MRXNPFEDSA-N 168098 US9073931, E15a::US9073931, E29a Oxysterols receptor LXR-beta 240 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168098&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736631 312525507 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312061 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(N)=O)c(n1)C(F)(F)F InChI=1S/C21H23F3N6O4S/c1-10(2)16-19-27-13-6-11(9-31)15(35(3,33)34)7-14(13)29(19)4-5-30(16)20-26-8-12(18(25)32)17(28-20)21(22,23)24/h6-8,10,16,31H,4-5,9H2,1-3H3,(H2,25,32)/t16-/m0/s1 XZVKGPBWXMHCFG-INIZCTEOSA-N 168099 US9073931, E15b::US9073931, E29b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168099&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736632 312525508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312062 CNC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C22H25F3N6O4S/c1-11(2)17-19-28-14-7-12(10-32)16(36(4,34)35)8-15(14)30(19)5-6-31(17)21-27-9-13(20(33)26-3)18(29-21)22(23,24)25/h7-9,11,17,32H,5-6,10H2,1-4H3,(H,26,33)/t17-/m1/s1 NXCDNSRNJQVGLH-QGZVFWFLSA-N 168100 US9073931, E16a Oxysterols receptor LXR-beta 376 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168100&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736633 312525509 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312063 CNC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@@H]1C(C)C InChI=1S/C22H25F3N6O4S/c1-11(2)17-19-28-14-7-12(10-32)16(36(4,34)35)8-15(14)30(19)5-6-31(17)21-27-9-13(20(33)26-3)18(29-21)22(23,24)25/h7-9,11,17,32H,5-6,10H2,1-4H3,(H,26,33)/t17-/m0/s1 NXCDNSRNJQVGLH-KRWDZBQOSA-N 168101 US9073931, E16b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168101&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736634 312525510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312064 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(=O)N(C)C)c(n1)C(F)(F)F InChI=1S/C23H27F3N6O4S/c1-12(2)18-20-28-15-8-13(11-33)17(37(5,35)36)9-16(15)31(20)6-7-32(18)22-27-10-14(21(34)30(3)4)19(29-22)23(24,25)26/h8-10,12,18,33H,6-7,11H2,1-5H3/t18-/m1/s1 ZCAGVFAMPNTRSJ-GOSISDBHSA-N 168102 US9073931, E17a Oxysterols receptor LXR-beta 220 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168102&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736635 312525511 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312065 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(=O)N(C)C)c(n1)C(F)(F)F InChI=1S/C23H27F3N6O4S/c1-12(2)18-20-28-15-8-13(11-33)17(37(5,35)36)9-16(15)31(20)6-7-32(18)22-27-10-14(21(34)30(3)4)19(29-22)23(24,25)26/h8-10,12,18,33H,6-7,11H2,1-5H3/t18-/m0/s1 ZCAGVFAMPNTRSJ-SFHVURJKSA-N 168103 US9073931, E17b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168103&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736790 312525512 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312066 COc1nc(ncc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C21H24F3N5O4S/c1-11(2)17-18-26-14-7-12(10-30)16(34(4,31)32)8-15(14)28(18)5-6-29(17)20-25-9-13(21(22,23)24)19(27-20)33-3/h7-9,11,17,30H,5-6,10H2,1-4H3/t17-/m1/s1 BGDPLINROWYUAR-QGZVFWFLSA-N 168104 US9073931, E18 Oxysterols receptor LXR-beta 8 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168104&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736791 312525513 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312067 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(CO)c(C)n1 InChI=1S/C21H27N5O4S/c1-12(2)19-20-24-16-7-14(10-27)18(31(4,29)30)8-17(16)25(20)5-6-26(19)21-22-9-15(11-28)13(3)23-21/h7-9,12,19,27-28H,5-6,10-11H2,1-4H3/t19-/m1/s1 RFTNNAZOBBBGFN-LJQANCHMSA-N 168105 US9073931, E19 Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168105&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736792 312525514 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312068 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(CO)c(n1)C1CC1 InChI=1S/C23H29N5O4S/c1-13(2)21-22-25-17-8-15(11-29)19(33(3,31)32)9-18(17)27(22)6-7-28(21)23-24-10-16(12-30)20(26-23)14-4-5-14/h8-10,13-14,21,29-30H,4-7,11-12H2,1-3H3/t21-/m1/s1 OSNFDPBMTJXLGE-OAQYLSRUSA-N 168106 US9073931, E20a Oxysterols receptor LXR-beta 110 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168106&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736793 312525515 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312069 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(CO)c(n1)C1CC1 InChI=1S/C23H29N5O4S/c1-13(2)21-22-25-17-8-15(11-29)19(33(3,31)32)9-18(17)27(22)6-7-28(21)23-24-10-16(12-30)20(26-23)14-4-5-14/h8-10,13-14,21,29-30H,4-7,11-12H2,1-3H3/t21-/m0/s1 OSNFDPBMTJXLGE-NRFANRHFSA-N 168107 US9073931, E20b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168107&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736794 312525516 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312070 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C)c(n1)C(F)(F)F InChI=1S/C21H24F3N5O3S/c1-11(2)17-19-26-14-7-13(10-30)16(33(4,31)32)8-15(14)28(19)5-6-29(17)20-25-9-12(3)18(27-20)21(22,23)24/h7-9,11,17,30H,5-6,10H2,1-4H3/t17-/m1/s1 ULLMSRMSGPWBDE-QGZVFWFLSA-N 168108 US9073931, E21 Oxysterols receptor LXR-beta 10 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168108&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736953 312525517 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312071 CC(C)[C@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)=O)c(n1)C(F)(F)F InChI=1S/C21H22F3N5O3S/c1-11(2)17-19-26-15-6-5-13(33(4,31)32)9-16(15)28(19)7-8-29(17)20-25-10-14(12(3)30)18(27-20)21(22,23)24/h5-6,9-11,17H,7-8H2,1-4H3/t17-/m1/s1 UVRFHLLVIGMMMM-QGZVFWFLSA-N 168109 US9073931, E22a Oxysterols receptor LXR-beta 12 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168109&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736148 312525518 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312072 CC(C)[C@@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)=O)c(n1)C(F)(F)F InChI=1S/C21H22F3N5O3S/c1-11(2)17-19-26-15-6-5-13(33(4,31)32)9-16(15)28(19)7-8-29(17)20-25-10-14(12(3)30)18(27-20)21(22,23)24/h5-6,9-11,17H,7-8H2,1-4H3/t17-/m0/s1 UVRFHLLVIGMMMM-KRWDZBQOSA-N 168110 US9073931, E22b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168110&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736149 312525519 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312073 CC(C)[C@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C22H26F3N5O3S/c1-12(2)17-19-27-15-7-6-13(34(5,32)33)10-16(15)29(19)8-9-30(17)20-26-11-14(21(3,4)31)18(28-20)22(23,24)25/h6-7,10-12,17,31H,8-9H2,1-5H3/t17-/m1/s1 LOFRRPNYSLDHRM-QGZVFWFLSA-N 168111 US9073931, E23a Oxysterols receptor LXR-beta 21 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168111&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935686 312525520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312074 CC(C)[C@@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C22H26F3N5O3S/c1-12(2)17-19-27-15-7-6-13(34(5,32)33)10-16(15)29(19)8-9-30(17)20-26-11-14(21(3,4)31)18(28-20)22(23,24)25/h6-7,10-12,17,31H,8-9H2,1-5H3/t17-/m0/s1 LOFRRPNYSLDHRM-KRWDZBQOSA-N 168112 US9073931, E23b Oxysterols receptor LXR-beta 2440 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168112&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935715 312525521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312075 CC(C)[C@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C21H24F3N5O3S/c1-11(2)17-19-26-15-6-5-13(33(4,31)32)9-16(15)28(19)7-8-29(17)20-25-10-14(12(3)30)18(27-20)21(22,23)24/h5-6,9-12,17,30H,7-8H2,1-4H3/t12?,17-/m1/s1 VGEORAURCJKCNM-RGUGMKFQSA-N 168113 US9073931, E24a::US9073931, E24b Oxysterols receptor LXR-beta 7 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168113&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935634 312525522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312076 CC(C)[C@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C21H24F3N5O3S/c1-11(2)17-19-26-15-6-5-13(33(4,31)32)9-16(15)28(19)7-8-29(17)20-25-10-14(12(3)30)18(27-20)21(22,23)24/h5-6,9-12,17,30H,7-8H2,1-4H3/t12?,17-/m1/s1 VGEORAURCJKCNM-RGUGMKFQSA-N 168113 US9073931, E24a::US9073931, E24b Oxysterols receptor LXR-beta 20 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168113&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935634 312525522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312077 CC(C)[C@@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C21H24F3N5O3S/c1-11(2)17-19-26-15-6-5-13(33(4,31)32)9-16(15)28(19)7-8-29(17)20-25-10-14(12(3)30)18(27-20)21(22,23)24/h5-6,9-12,17,30H,7-8H2,1-4H3/t12?,17-/m0/s1 VGEORAURCJKCNM-TYJDENFWSA-N 168115 US9073931, E24c::US9073931, E24d Oxysterols receptor LXR-beta 1690 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168115&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935626 312525523 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312078 CC(C)[C@@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C21H24F3N5O3S/c1-11(2)17-19-26-15-6-5-13(33(4,31)32)9-16(15)28(19)7-8-29(17)20-25-10-14(12(3)30)18(27-20)21(22,23)24/h5-6,9-12,17,30H,7-8H2,1-4H3/t12?,17-/m0/s1 VGEORAURCJKCNM-TYJDENFWSA-N 168115 US9073931, E24c::US9073931, E24d Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168115&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935626 312525523 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312079 CC(C)[C@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C20H22F3N5O3S/c1-11(2)16-18-25-14-5-4-13(32(3,30)31)8-15(14)27(18)6-7-28(16)19-24-9-12(10-29)17(26-19)20(21,22)23/h4-5,8-9,11,16,29H,6-7,10H2,1-3H3/t16-/m1/s1 MWSOCMMZIFOCRI-MRXNPFEDSA-N 168117 US9073931, E25a Oxysterols receptor LXR-beta 6 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168117&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935635 312525524 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312080 CC(C)[C@@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C20H22F3N5O3S/c1-11(2)16-18-25-14-5-4-13(32(3,30)31)8-15(14)27(18)6-7-28(16)19-24-9-12(10-29)17(26-19)20(21,22)23/h4-5,8-9,11,16,29H,6-7,10H2,1-3H3/t16-/m0/s1 MWSOCMMZIFOCRI-INIZCTEOSA-N 168118 US9073931, E25b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168118&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117935627 312525525 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312081 CC(C)C1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(C)=O)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-11(2)18-20-27-15-7-13(10-31)17(35(4,33)34)8-16(15)29(20)5-6-30(18)21-26-9-14(12(3)32)19(28-21)22(23,24)25/h7-9,11,18,31H,5-6,10H2,1-4H3 LWXOLPDIDYBJQJ-UHFFFAOYSA-N 168119 US9073931, E26 Oxysterols receptor LXR-beta 7 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168119&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89816054 312525526 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312082 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C23H28F3N5O4S/c1-12(2)18-20-28-15-8-13(11-32)17(36(5,34)35)9-16(15)30(20)6-7-31(18)21-27-10-14(22(3,4)33)19(29-21)23(24,25)26/h8-10,12,18,32-33H,6-7,11H2,1-5H3/t18-/m1/s1 IUMMDSSCERZSTJ-GOSISDBHSA-N 168079 US9073931, E27a::US9073931, E7a Oxysterols receptor LXR-beta 2 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736150 312525493 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312083 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C23H28F3N5O4S/c1-12(2)18-20-28-15-8-13(11-32)17(36(5,34)35)9-16(15)30(20)6-7-31(18)21-27-10-14(22(3,4)33)19(29-21)23(24,25)26/h8-10,12,18,32-33H,6-7,11H2,1-5H3/t18-/m0/s1 IUMMDSSCERZSTJ-SFHVURJKSA-N 168080 US9073931, E27b::US9073931, E7b Oxysterols receptor LXR-beta 712 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736151 312525494 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312084 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)C1C(C)C InChI=1S/C23H26F3N5O5S/c1-5-36-21(33)14-10-27-22(29-19(14)23(24,25)26)31-7-6-30-16-9-17(37(4,34)35)13(11-32)8-15(16)28-20(30)18(31)12(2)3/h8-10,12,18,32H,5-7,11H2,1-4H3 YXXFEOBGLYBWLG-UHFFFAOYSA-N 168122 US9073931, E28 Oxysterols receptor LXR-beta 5 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168122&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 78164448 312525527 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312085 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(N)=O)c(n1)C(F)(F)F InChI=1S/C21H23F3N6O4S/c1-10(2)16-19-27-13-6-11(9-31)15(35(3,33)34)7-14(13)29(19)4-5-30(16)20-26-8-12(18(25)32)17(28-20)21(22,23)24/h6-8,10,16,31H,4-5,9H2,1-3H3,(H2,25,32)/t16-/m1/s1 XZVKGPBWXMHCFG-MRXNPFEDSA-N 168098 US9073931, E15a::US9073931, E29a Oxysterols receptor LXR-beta 50 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168098&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736631 312525507 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312086 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1ncc(C(N)=O)c(n1)C(F)(F)F InChI=1S/C21H23F3N6O4S/c1-10(2)16-19-27-13-6-11(9-31)15(35(3,33)34)7-14(13)29(19)4-5-30(16)20-26-8-12(18(25)32)17(28-20)21(22,23)24/h6-8,10,16,31H,4-5,9H2,1-3H3,(H2,25,32)/t16-/m0/s1 XZVKGPBWXMHCFG-INIZCTEOSA-N 168099 US9073931, E15b::US9073931, E29b Oxysterols receptor LXR-beta >2500 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168099&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71736632 312525508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 312087 COC(=O)c1cnc(nc1C(F)(F)F)N1CCn2c(nc3cc(CO)c(cc23)S(C)(=O)=O)[C@H]1C(C)C InChI=1S/C22H24F3N5O5S/c1-11(2)17-19-27-14-7-12(10-31)16(36(4,33)34)8-15(14)29(19)5-6-30(17)21-26-9-13(20(32)35-3)18(28-21)22(23,24)25/h7-9,11,17,31H,5-6,10H2,1-4H3/t17-/m1/s1 ZWGZCSXCYWYFTL-QGZVFWFLSA-N 168125 US9073931, E30 Oxysterols receptor LXR-beta 10 25.00 C US Patent 10.7270/Q26W98VC aid1801414 US9073931 Leftheris, K; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168125&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89816152 312525528 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068304 CCN(C(COc1ccc(CC(O)=O)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C27H24ClF6NO4/c1-2-35(22-13-10-19(15-21(22)28)25(38,26(29,30)31)27(32,33)34)23(18-6-4-3-5-7-18)16-39-20-11-8-17(9-12-20)14-24(36)37/h3-13,15,23,38H,2,14,16H2,1H3,(H,36,37) NIFOQZBOAOCXKN-UHFFFAOYSA-N 50192152 2-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)acetic acid::CHEMBL214546 Oxysterols receptor LXR-beta 2400 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192152&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416992 104075104 CHEMBL214546 C03768 ZINC38149592 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068305 CCN(C(C(=O)N(C)C)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H22F6N2O2/c1-4-29(17(18(30)28(2)3)14-8-6-5-7-9-14)16-12-10-15(11-13-16)19(31,20(22,23)24)21(25,26)27/h5-13,17,31H,4H2,1-3H3 JFQRHNPSAQDYTO-UHFFFAOYSA-N 50192122 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-N,N-dimethyl-2-phenylacetamide::CHEMBL215775 Oxysterols receptor LXR-beta 2300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192122&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416988 104075074 CHEMBL215775 ZINC38149646 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068310 CCN(C(COCC(=O)NC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H24F6N2O3/c1-3-30(18(13-33-14-19(31)29-2)15-7-5-4-6-8-15)17-11-9-16(10-12-17)20(32,21(23,24)25)22(26,27)28/h4-12,18,32H,3,13-14H2,1-2H3,(H,29,31) VYMLRIABXQHHAB-UHFFFAOYSA-N 50192119 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)-N-methylacetamide::CHEMBL385546 Oxysterols receptor LXR-beta >40000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192119&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416991 104075071 CHEMBL385546 ZINC40766653 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068311 CCN(C(C(O)=O)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H17F6NO3/c1-2-26(15(16(27)28)12-6-4-3-5-7-12)14-10-8-13(9-11-14)17(29,18(20,21)22)19(23,24)25/h3-11,15,29H,2H2,1H3,(H,27,28) XBMKRWIORLIFDX-UHFFFAOYSA-N 50192129 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylacetic acid::CHEMBL215327 Oxysterols receptor LXR-beta 5400 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192129&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416818 104075081 CHEMBL215327 ZINC38149631 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068312 CCN(C(C(=O)NC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H20F6N2O2/c1-3-28(16(17(29)27-2)13-7-5-4-6-8-13)15-11-9-14(10-12-15)18(30,19(21,22)23)20(24,25)26/h4-12,16,30H,3H2,1-2H3,(H,27,29) HYMGUTROAWALBA-UHFFFAOYSA-N 50192110 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-N-methyl-2-phenylacetamide::CHEMBL215154 Oxysterols receptor LXR-beta 11000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192110&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416819 104075062 CHEMBL215154 ZINC40568166 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068313 CCN(C(COCc1ccccc1)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H25F6NO2/c1-2-33(22-15-13-21(14-16-22)24(34,25(27,28)29)26(30,31)32)23(20-11-7-4-8-12-20)18-35-17-19-9-5-3-6-10-19/h3-16,23,34H,2,17-18H2,1H3 DHVMIPXODCJNOG-UHFFFAOYSA-N 50192121 2-(4-((2-(benzyloxy)-1-phenylethyl)(ethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215647 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192121&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416822 104075073 CHEMBL215647 ZINC38149606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068314 CCN(CCc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO/c1-2-26(13-12-14-6-4-3-5-7-14)16-10-8-15(9-11-16)17(27,18(20,21)22)19(23,24)25/h3-11,27H,2,12-13H2,1H3 AHHXWYOHMGBGIR-UHFFFAOYSA-N 50192151 2-(4-(ethyl(phenethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215585 Oxysterols receptor LXR-beta 610 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192151&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11639715 104075103 CHEMBL215585 ZINC35983441 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068315 CCN(C(COC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H21F6NO2/c1-3-27(17(13-29-2)14-7-5-4-6-8-14)16-11-9-15(10-12-16)18(28,19(21,22)23)20(24,25)26/h4-12,17,28H,3,13H2,1-2H3 RTQPHBRRDAKJST-UHFFFAOYSA-N 50192123 2-(4-(ethyl(2-methoxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215598 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192123&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416821 104075075 CHEMBL215598 ZINC38149608 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068316 CCN(C(C(=O)OC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H19F6NO3/c1-3-27(16(17(28)30-2)13-7-5-4-6-8-13)15-11-9-14(10-12-15)18(29,19(21,22)23)20(24,25)26/h4-12,16,29H,3H2,1-2H3 KNYJKOYEMDLHCB-UHFFFAOYSA-N 50192132 CHEMBL214942::methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylacetate Oxysterols receptor LXR-beta 900 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192132&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416799 104075084 CHEMBL214942 ZINC38149634 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068145 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(C)(C(=O)OC)c1ccccc1 InChI=1S/C21H21F6NO3/c1-4-28(18(2,17(29)31-3)14-8-6-5-7-9-14)16-12-10-15(11-13-16)19(30,20(22,23)24)21(25,26)27/h5-13,30H,4H2,1-3H3 GXMQHNQBWIJYMO-UHFFFAOYSA-N 50192138 CHEMBL215904::methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylpropanoate Oxysterols receptor LXR-beta 30 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192138&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417046 104075090 CHEMBL215904 ZINC38149624 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068146 CCN(C(C(=O)N1CCOCC1)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H24F6N2O3/c1-2-31(18-10-8-17(9-11-18)21(33,22(24,25)26)23(27,28)29)19(16-6-4-3-5-7-16)20(32)30-12-14-34-15-13-30/h3-11,19,33H,2,12-15H2,1H3 CWFLKUZQTTZOMJ-UHFFFAOYSA-N 50192112 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-1-morpholino-2-phenylethanone::CHEMBL385544 Oxysterols receptor LXR-beta 2300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192112&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417045 104075064 CHEMBL385544 ZINC38149626 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068147 CCN(C(COc1ccc(cc1)C(O)=O)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H22ClF6NO4/c1-2-34(21-13-10-18(14-20(21)27)24(37,25(28,29)30)26(31,32)33)22(16-6-4-3-5-7-16)15-38-19-11-8-17(9-12-19)23(35)36/h3-14,22,37H,2,15H2,1H3,(H,35,36) NFIGPODJIQQYKF-UHFFFAOYSA-N 50192150 4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)benzoic acid::CHEMBL386260 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192150&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416756 104075102 CHEMBL386260 ZINC38149594 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068148 CCN(c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F)C(CC)(C(=O)OC)c1ccccc1 InChI=1S/C22H22ClF6NO3/c1-4-19(18(31)33-3,14-9-7-6-8-10-14)30(5-2)17-12-11-15(13-16(17)23)20(32,21(24,25)26)22(27,28)29/h6-13,32H,4-5H2,1-3H3 PDENOBIOQDVWAN-UHFFFAOYSA-N 50192153 CHEMBL215167::methyl 2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylbutanoate Oxysterols receptor LXR-beta 30 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192153&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416897 104075105 CHEMBL215167 ZINC38149620 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068149 CCN(CC(O)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(12-16(27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3 AQQQQVJBCMSSHB-UHFFFAOYSA-N 50192147 2-(4-(ethyl(2-hydroxy-2-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL448111 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192147&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11661439 104075099 CHEMBL448111 ZINC35951291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068150 COC(=O)C1(CCCCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)c1ccccc1 InChI=1S/C22H21F6NO3/c1-32-18(30)19(15-7-3-2-4-8-15)13-5-6-14-29(19)17-11-9-16(10-12-17)20(31,21(23,24)25)22(26,27)28/h2-4,7-12,31H,5-6,13-14H2,1H3 HFFCHXHRFPTTEV-UHFFFAOYSA-N 50192145 CHEMBL383945::methyl 1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-2-phenylpiperidine-2-carboxylate Oxysterols receptor LXR-beta 30 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192145&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416930 104075097 CHEMBL383945 ZINC38149614 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068151 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 70 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068152 CCN([C@H](CO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(16(12-27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3/t16-/m1/s1 QSPAMLVMIBGBJK-MRXNPFEDSA-N 50192140 (S)-2-(4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214832 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192140&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416803 104075092 CHEMBL214832 ZINC38149609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068153 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(CC)(C(=O)OC)c1ccccc1 InChI=1S/C22H23F6NO3/c1-4-19(18(30)32-3,15-9-7-6-8-10-15)29(5-2)17-13-11-16(12-14-17)20(31,21(23,24)25)22(26,27)28/h6-14,31H,4-5H2,1-3H3 WRDYYYJMUBDBTD-UHFFFAOYSA-N 50192131 CHEMBL263089::methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylbutanoate Oxysterols receptor LXR-beta 40 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192131&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417068 104075083 CHEMBL263089 ZINC38149622 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068155 CCN(C(C(=O)N1CCCCC1)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C24H26F6N2O2/c1-2-32(19-13-11-18(12-14-19)22(34,23(25,26)27)24(28,29)30)20(17-9-5-3-6-10-17)21(33)31-15-7-4-8-16-31/h3,5-6,9-14,20,34H,2,4,7-8,15-16H2,1H3 WNWFTAJJMGMWDJ-UHFFFAOYSA-N 50192146 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenyl-1-(piperidin-1-yl)ethanone::CHEMBL409212 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192146&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417023 104075098 CHEMBL409212 ZINC38149628 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068158 CCN([C@@H](CO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(16(12-27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3/t16-/m0/s1 QSPAMLVMIBGBJK-INIZCTEOSA-N 50192116 (R)-2-(4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL385489 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192116&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416802 104075068 CHEMBL385489 ZINC38149610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068162 CCN([C@H](CO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(16(12-27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3/t16-/m1/s1 QSPAMLVMIBGBJK-MRXNPFEDSA-N 50192140 (S)-2-(4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214832 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192140&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416803 104075092 CHEMBL214832 ZINC38149609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068166 OC(c1ccc(N(Cc2ccccc2)CC(F)(F)F)c(Cl)c1)(C(F)(F)F)C(F)(F)F InChI=1S/C18H13ClF9NO/c19-13-8-12(16(30,17(23,24)25)18(26,27)28)6-7-14(13)29(10-15(20,21)22)9-11-4-2-1-3-5-11/h1-8,30H,9-10H2 WZWCXVXAVYKLCU-UHFFFAOYSA-N 50192109 2-(4-(benzyl(2,2,2-trifluoroethyl)amino)-3-chlorophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL384246 Oxysterols receptor LXR-beta 3 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192109&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11655676 104075061 CHEMBL384246 ZINC38149643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068169 CCN(C(C(=O)N(C)C)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H22F6N2O2/c1-4-29(17(18(30)28(2)3)14-8-6-5-7-9-14)16-12-10-15(11-13-16)19(31,20(22,23)24)21(25,26)27/h5-13,17,31H,4H2,1-3H3 JFQRHNPSAQDYTO-UHFFFAOYSA-N 50192122 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-N,N-dimethyl-2-phenylacetamide::CHEMBL215775 Oxysterols receptor LXR-beta 6300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192122&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416988 104075074 CHEMBL215775 ZINC38149646 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068176 CCN(Cc1nc(oc1C)-c1cccc(Cl)c1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H18Cl2F6N2O2/c1-3-32(11-17-12(2)34-19(31-17)13-5-4-6-15(23)9-13)18-8-7-14(10-16(18)24)20(33,21(25,26)27)22(28,29)30/h4-10,33H,3,11H2,1-2H3 KNISWKWBHJJIBH-UHFFFAOYSA-N 50192137 2-(3-chloro-4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)methyl)(ethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215108 Oxysterols receptor LXR-beta 4 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192137&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11713433 104075089 CHEMBL215108 ZINC38149639 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068186 CCN(C(COc1ccc(CC(O)=O)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C27H24ClF6NO4/c1-2-35(22-13-10-19(15-21(22)28)25(38,26(29,30)31)27(32,33)34)23(18-6-4-3-5-7-18)16-39-20-11-8-17(9-12-20)14-24(36)37/h3-13,15,23,38H,2,14,16H2,1H3,(H,36,37) NIFOQZBOAOCXKN-UHFFFAOYSA-N 50192152 2-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)acetic acid::CHEMBL214546 Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192152&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416992 104075104 CHEMBL214546 C03768 ZINC38149592 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068188 CCN(C(CO)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H18ClF6NO2/c1-2-27(16(11-28)12-6-4-3-5-7-12)15-9-8-13(10-14(15)20)17(29,18(21,22)23)19(24,25)26/h3-10,16,28-29H,2,11H2,1H3 QTIICHXFYACDHK-UHFFFAOYSA-N 50192124 2-(3-chloro-4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214741 Oxysterols receptor LXR-beta 90 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192124&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416951 104075076 CHEMBL214741 ZINC38149612 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068189 CCN(Cc1nc(oc1C)-c1cccc(c1)C(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H19F9N2O2/c1-3-34(17-9-7-15(8-10-17)20(35,22(27,28)29)23(30,31)32)12-18-13(2)36-19(33-18)14-5-4-6-16(11-14)21(24,25)26/h4-11,35H,3,12H2,1-2H3 DPUDSUKLVWJOHF-UHFFFAOYSA-N 50192136 2-(4-(ethyl((5-methyl-2-(3-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214867 Oxysterols receptor LXR-beta 3 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192136&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11584508 104075088 CHEMBL214867 ZINC38149637 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068190 Cc1oc(nc1CN(CC(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)-c1cccc(Cl)c1 InChI=1S/C22H16ClF9N2O2/c1-12-17(33-18(36-12)13-3-2-4-15(23)9-13)10-34(11-19(24,25)26)16-7-5-14(6-8-16)20(35,21(27,28)29)22(30,31)32/h2-9,35H,10-11H2,1H3 XETFRQSXUSJFTQ-UHFFFAOYSA-N 50192128 2-(4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)methyl)(2,2,2-trifluoroethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL386603 Oxysterols receptor LXR-beta 50 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192128&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11713676 104075080 CHEMBL386603 ZINC38149638 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068191 CCN(C(COc1ccc(CC(=O)OC)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H26ClF6NO4/c1-3-36(23-14-11-20(16-22(23)29)26(38,27(30,31)32)28(33,34)35)24(19-7-5-4-6-8-19)17-40-21-12-9-18(10-13-21)15-25(37)39-2/h4-14,16,24,38H,3,15,17H2,1-2H3 DCMCTSPBOPLCIX-UHFFFAOYSA-N 50192154 CHEMBL215959::methyl 2-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)acetate Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192154&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417052 104075106 CHEMBL215959 ZINC38149598 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068192 CCN(C(CO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(16(12-27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3 QSPAMLVMIBGBJK-UHFFFAOYSA-N 50192120 2-(4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL385411 Oxysterols receptor LXR-beta 900 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192120&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416950 104075072 CHEMBL385411 ZINC38149610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068193 CCN(CCc1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H18ClF6NO/c1-2-27(11-10-13-6-4-3-5-7-13)16-9-8-14(12-15(16)20)17(28,18(21,22)23)19(24,25)26/h3-9,12,28H,2,10-11H2,1H3 IUJVGMXTNWYJCB-UHFFFAOYSA-N 50192144 2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL386530 Oxysterols receptor LXR-beta 90 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192144&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11611604 104075096 CHEMBL386530 ZINC35933711 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068194 CCN(C(COCC(=O)NC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H24F6N2O3/c1-3-30(18(13-33-14-19(31)29-2)15-7-5-4-6-8-15)17-11-9-16(10-12-17)20(32,21(23,24)25)22(26,27)28/h4-12,18,32H,3,13-14H2,1-2H3,(H,29,31) VYMLRIABXQHHAB-UHFFFAOYSA-N 50192119 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)-N-methylacetamide::CHEMBL385546 Oxysterols receptor LXR-beta 31000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192119&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416991 104075071 CHEMBL385546 ZINC40766653 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068195 CCN(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C18H17F6NO/c1-2-25(12-13-6-4-3-5-7-13)15-10-8-14(9-11-15)16(26,17(19,20)21)18(22,23)24/h3-11,26H,2,12H2,1H3 UWRRECCPOPWQFF-UHFFFAOYSA-N 50192118 2-(4-(benzyl(ethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL383959 Oxysterols receptor LXR-beta 30 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192118&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11574384 104075070 CHEMBL383959 ZINC35847006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068196 CCN(Cc1ccncc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H16F6N2O/c1-2-25(11-12-7-9-24-10-8-12)14-5-3-13(4-6-14)15(26,16(18,19)20)17(21,22)23/h3-10,26H,2,11H2,1H3 OLIMPPLJAGRECO-UHFFFAOYSA-N 50192111 2-(4-(ethyl(pyridin-4-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214275 Oxysterols receptor LXR-beta 1680 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192111&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11696530 104075063 CHEMBL214275 ZINC38149641 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068197 CCN(Cc1cccnc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H16F6N2O/c1-2-25(11-12-4-3-9-24-10-12)14-7-5-13(6-8-14)15(26,16(18,19)20)17(21,22)23/h3-10,26H,2,11H2,1H3 FWZYPDLJUKHKNM-UHFFFAOYSA-N 50192135 2-(4-(ethyl(pyridin-3-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL216055 Oxysterols receptor LXR-beta 2320 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192135&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11559891 104075087 CHEMBL216055 ZINC35815010 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068198 CCN(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C18H17F6NO/c1-2-25(12-13-6-4-3-5-7-13)15-10-8-14(9-11-15)16(26,17(19,20)21)18(22,23)24/h3-11,26H,2,12H2,1H3 UWRRECCPOPWQFF-UHFFFAOYSA-N 50192118 2-(4-(benzyl(ethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL383959 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192118&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11574384 104075070 CHEMBL383959 ZINC35847006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068199 CCN(Cc1nc(oc1C)-c1cccc(c1)C(F)(F)F)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H18ClF9N2O2/c1-3-35(18-8-7-14(10-16(18)24)20(36,22(28,29)30)23(31,32)33)11-17-12(2)37-19(34-17)13-5-4-6-15(9-13)21(25,26)27/h4-10,36H,3,11H2,1-2H3 KIBPLVVEBAJZRG-UHFFFAOYSA-N 50192113 2-(3-chloro-4-(ethyl((5-methyl-2-(3-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL383944 Oxysterols receptor LXR-beta 7 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192113&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11721039 104075065 CHEMBL383944 ZINC38149636 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068200 CCN(C(COc1ccc(cc1)C(O)=O)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H22ClF6NO4/c1-2-34(21-13-10-18(14-20(21)27)24(37,25(28,29)30)26(31,32)33)22(16-6-4-3-5-7-16)15-38-19-11-8-17(9-12-19)23(35)36/h3-14,22,37H,2,15H2,1H3,(H,35,36) NFIGPODJIQQYKF-UHFFFAOYSA-N 50192150 4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)benzoic acid::CHEMBL386260 Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192150&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416756 104075102 CHEMBL386260 ZINC38149594 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068201 OC(c1ccc(N(Cc2ccccc2)CC(F)(F)F)c(Cl)c1)(C(F)(F)F)C(F)(F)F InChI=1S/C18H13ClF9NO/c19-13-8-12(16(30,17(23,24)25)18(26,27)28)6-7-14(13)29(10-15(20,21)22)9-11-4-2-1-3-5-11/h1-8,30H,9-10H2 WZWCXVXAVYKLCU-UHFFFAOYSA-N 50192109 2-(4-(benzyl(2,2,2-trifluoroethyl)amino)-3-chlorophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL384246 Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192109&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11655676 104075061 CHEMBL384246 ZINC38149643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068202 CCN(C(COCC(=O)N(C)C)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H26F6N2O3/c1-4-31(19(16-8-6-5-7-9-16)14-34-15-20(32)30(2)3)18-12-10-17(11-13-18)21(33,22(24,25)26)23(27,28)29/h5-13,19,33H,4,14-15H2,1-3H3 HSXPHPZTVBAFKE-UHFFFAOYSA-N 50192114 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)-N,N-dimethylacetamide::CHEMBL215129 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192114&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417026 104075066 CHEMBL215129 ZINC38149602 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068205 CCN(Cc1nc(oc1C)-c1cccc(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H19ClF6N2O2/c1-3-31(12-18-13(2)33-19(30-18)14-5-4-6-16(23)11-14)17-9-7-15(8-10-17)20(32,21(24,25)26)22(27,28)29/h4-11,32H,3,12H2,1-2H3 BATZVQCOFGOVMF-UHFFFAOYSA-N 50192117 2-(4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)methyl)(methyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215789 Oxysterols receptor LXR-beta 60 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192117&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11698867 104075069 CHEMBL215789 ZINC38149640 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068206 CCN(C(COc1ccc(CCC(O)=O)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H26ClF6NO4/c1-2-36(23-14-11-20(16-22(23)29)26(39,27(30,31)32)28(33,34)35)24(19-6-4-3-5-7-19)17-40-21-12-8-18(9-13-21)10-15-25(37)38/h3-9,11-14,16,24,39H,2,10,15,17H2,1H3,(H,37,38) FJTZZSUSVZOHJU-UHFFFAOYSA-N 50192115 3-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)propanoic acid::CHEMBL269442 Oxysterols receptor LXR-beta 7 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192115&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417028 104075067 CHEMBL269442 ZINC38149590 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068207 CCN(C(COc1ccc(cc1)C(=O)OC)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C27H24ClF6NO4/c1-3-35(22-14-11-19(15-21(22)28)25(37,26(29,30)31)27(32,33)34)23(17-7-5-4-6-8-17)16-39-20-12-9-18(10-13-20)24(36)38-2/h4-15,23,37H,3,16H2,1-2H3 QGRQWRDAMFVQJV-UHFFFAOYSA-N 50192149 CHEMBL215130::methyl 4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)benzoate Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192149&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417027 104075101 CHEMBL215130 ZINC38149600 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068208 CCN(C(COCC(O)=O)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H21F6NO4/c1-2-28(17(12-32-13-18(29)30)14-6-4-3-5-7-14)16-10-8-15(9-11-16)19(31,20(22,23)24)21(25,26)27/h3-11,17,31H,2,12-13H2,1H3,(H,29,30) JEJWNQZGLAXVKT-UHFFFAOYSA-N 50192130 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)acetic acid::CHEMBL215445 Oxysterols receptor LXR-beta >40000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192130&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416861 104075082 CHEMBL215445 ZINC38149648 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068212 CCN(Cc1nc(oc1C)-c1cccc(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H19ClF6N2O2/c1-3-31(12-18-13(2)33-19(30-18)14-5-4-6-16(23)11-14)17-9-7-15(8-10-17)20(32,21(24,25)26)22(27,28)29/h4-11,32H,3,12H2,1-2H3 BATZVQCOFGOVMF-UHFFFAOYSA-N 50192117 2-(4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)methyl)(methyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215789 Oxysterols receptor LXR-beta 5 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192117&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11698867 104075069 CHEMBL215789 ZINC38149640 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068225 OC(c1ccc(cc1)N(Cc1ccccc1)CC(F)(F)F)(C(F)(F)F)C(F)(F)F InChI=1S/C18H14F9NO/c19-15(20,21)11-28(10-12-4-2-1-3-5-12)14-8-6-13(7-9-14)16(29,17(22,23)24)18(25,26)27/h1-9,29H,10-11H2 MUUGHUBMRJKYSW-UHFFFAOYSA-N 50192133 2-(4-(benzyl(2,2,2-trifluoroethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214777 Oxysterols receptor LXR-beta 60 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192133&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11582802 104075085 CHEMBL214777 ZINC38149644 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068226 CCN(CCc1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H18ClF6NO/c1-2-27(11-10-13-6-4-3-5-7-13)16-9-8-14(12-15(16)20)17(28,18(21,22)23)19(24,25)26/h3-9,12,28H,2,10-11H2,1H3 IUJVGMXTNWYJCB-UHFFFAOYSA-N 50192144 2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL386530 Oxysterols receptor LXR-beta 3 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192144&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11611604 104075096 CHEMBL386530 ZINC35933711 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068227 OC(c1ccc(cc1)N(Cc1ccccc1)CC(F)(F)F)(C(F)(F)F)C(F)(F)F InChI=1S/C18H14F9NO/c19-15(20,21)11-28(10-12-4-2-1-3-5-12)14-8-6-13(7-9-14)16(29,17(22,23)24)18(25,26)27/h1-9,29H,10-11H2 MUUGHUBMRJKYSW-UHFFFAOYSA-N 50192133 2-(4-(benzyl(2,2,2-trifluoroethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214777 Oxysterols receptor LXR-beta 200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192133&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11582802 104075085 CHEMBL214777 ZINC38149644 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068228 CCN(C(COCC(=O)OC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H23F6NO4/c1-3-29(18(13-33-14-19(30)32-2)15-7-5-4-6-8-15)17-11-9-16(10-12-17)20(31,21(23,24)25)22(26,27)28/h4-12,18,31H,3,13-14H2,1-2H3 KPCMZDDOZHFXBR-UHFFFAOYSA-N 50192125 CHEMBL385052::methyl 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)acetate Oxysterols receptor LXR-beta 900 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192125&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416842 104075077 CHEMBL385052 ZINC38149604 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068229 CCN(C(COCCO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H23F6NO3/c1-2-28(18(14-31-13-12-29)15-6-4-3-5-7-15)17-10-8-16(9-11-17)19(30,20(22,23)24)21(25,26)27/h3-11,18,29-30H,2,12-14H2,1H3 JALYOEQAGVCURF-UHFFFAOYSA-N 50192143 2-(4-(ethyl(2-(2-hydroxyethoxy)-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214915 Oxysterols receptor LXR-beta >40000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192143&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416843 104075095 CHEMBL214915 ZINC40568373 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068230 CCN(C(COc1ccc(CCC(=O)OC)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C29H28ClF6NO4/c1-3-37(24-15-12-21(17-23(24)30)27(39,28(31,32)33)29(34,35)36)25(20-7-5-4-6-8-20)18-41-22-13-9-19(10-14-22)11-16-26(38)40-2/h4-10,12-15,17,25,39H,3,11,16,18H2,1-2H3 UUUSQFKWCMPEFI-UHFFFAOYSA-N 50192139 CHEMBL214687::methyl 3-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)propanoate Oxysterols receptor LXR-beta 50 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192139&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417072 104075091 CHEMBL214687 ZINC38149596 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068231 CCN([C@@H](CO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(16(12-27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3/t16-/m0/s1 QSPAMLVMIBGBJK-INIZCTEOSA-N 50192116 (R)-2-(4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL385489 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192116&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416802 104075068 CHEMBL385489 ZINC38149610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068232 COC(=O)C1(CCCCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)c1ccccc1 InChI=1S/C22H21F6NO3/c1-32-18(30)19(15-7-3-2-4-8-15)13-5-6-14-29(19)17-11-9-16(10-12-17)20(31,21(23,24)25)22(26,27)28/h2-4,7-12,31H,5-6,13-14H2,1H3 HFFCHXHRFPTTEV-UHFFFAOYSA-N 50192145 CHEMBL383945::methyl 1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-2-phenylpiperidine-2-carboxylate Oxysterols receptor LXR-beta 40 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192145&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416930 104075097 CHEMBL383945 ZINC38149614 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068233 CCN(CC(O)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(12-16(27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3 AQQQQVJBCMSSHB-UHFFFAOYSA-N 50192147 2-(4-(ethyl(2-hydroxy-2-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL448111 Oxysterols receptor LXR-beta 200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192147&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11661439 104075099 CHEMBL448111 ZINC35951291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068235 CCN(C(C(=O)OC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H19F6NO3/c1-3-27(16(17(28)30-2)13-7-5-4-6-8-13)15-11-9-14(10-12-15)18(29,19(21,22)23)20(24,25)26/h4-12,16,29H,3H2,1-2H3 KNYJKOYEMDLHCB-UHFFFAOYSA-N 50192132 CHEMBL214942::methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylacetate Oxysterols receptor LXR-beta 2200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192132&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416799 104075084 CHEMBL214942 ZINC38149634 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068239 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(CC)(C(=O)OC)c1ccccc1 InChI=1S/C22H23F6NO3/c1-4-19(18(30)32-3,15-9-7-6-8-10-15)29(5-2)17-13-11-16(12-14-17)20(31,21(23,24)25)22(26,27)28/h6-14,31H,4-5H2,1-3H3 WRDYYYJMUBDBTD-UHFFFAOYSA-N 50192131 CHEMBL263089::methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylbutanoate Oxysterols receptor LXR-beta 70 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192131&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417068 104075083 CHEMBL263089 ZINC38149622 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068241 CCN(C(COCC(O)=O)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H21F6NO4/c1-2-28(17(12-32-13-18(29)30)14-6-4-3-5-7-14)16-10-8-15(9-11-16)19(31,20(22,23)24)21(25,26)27/h3-11,17,31H,2,12-13H2,1H3,(H,29,30) JEJWNQZGLAXVKT-UHFFFAOYSA-N 50192130 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)acetic acid::CHEMBL215445 Oxysterols receptor LXR-beta 90000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192130&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416861 104075082 CHEMBL215445 ZINC38149648 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068245 CCN(C(CO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO2/c1-2-26(16(12-27)13-6-4-3-5-7-13)15-10-8-14(9-11-15)17(28,18(20,21)22)19(23,24)25/h3-11,16,27-28H,2,12H2,1H3 QSPAMLVMIBGBJK-UHFFFAOYSA-N 50192120 2-(4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL385411 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192120&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416950 104075072 CHEMBL385411 ZINC38149610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068246 CCN(C(CO)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H18ClF6NO2/c1-2-27(16(11-28)12-6-4-3-5-7-12)15-9-8-13(10-14(15)20)17(29,18(21,22)23)19(24,25)26/h3-10,16,28-29H,2,11H2,1H3 QTIICHXFYACDHK-UHFFFAOYSA-N 50192124 2-(3-chloro-4-(ethyl(2-hydroxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214741 Oxysterols receptor LXR-beta 200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192124&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416951 104075076 CHEMBL214741 ZINC38149612 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068247 CCN(Cc1cscn1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C15H14F6N2OS/c1-2-23(7-11-8-25-9-22-11)12-5-3-10(4-6-12)13(24,14(16,17)18)15(19,20)21/h3-6,8-9,24H,2,7H2,1H3 DBCGQWBJSYJXSD-UHFFFAOYSA-N 50192142 1,1,1,3,3,3-hexafluoro-2-(4-(methyl(thiazol-4-ylmethyl)amino)phenyl)propan-2-ol::CHEMBL386174 Oxysterols receptor LXR-beta 200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192142&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11617908 104075094 CHEMBL386174 ZINC35942802 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068248 CCN(C(C(=O)N1CCCCC1)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C24H26F6N2O2/c1-2-32(19-13-11-18(12-14-19)22(34,23(25,26)27)24(28,29)30)20(17-9-5-3-6-10-17)21(33)31-15-7-4-8-16-31/h3,5-6,9-14,20,34H,2,4,7-8,15-16H2,1H3 WNWFTAJJMGMWDJ-UHFFFAOYSA-N 50192146 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenyl-1-(piperidin-1-yl)ethanone::CHEMBL409212 Oxysterols receptor LXR-beta 2200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192146&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417023 104075098 CHEMBL409212 ZINC38149628 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068249 Cc1oc(nc1CN(CC(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)-c1cccc(c1)C(F)(F)F InChI=1S/C23H16F12N2O2/c1-12-17(36-18(39-12)13-3-2-4-15(9-13)21(27,28)29)10-37(11-19(24,25)26)16-7-5-14(6-8-16)20(38,22(30,31)32)23(33,34)35/h2-9,38H,10-11H2,1H3 QOUARJFUWURIGY-UHFFFAOYSA-N 50192126 1,1,1,3,3,3-hexafluoro-2-(4-(((5-methyl-2-(3-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)(2,2,2-trifluoroethyl)amino)phenyl)propan-2-ol::CHEMBL215042 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192126&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11592304 104075078 CHEMBL215042 ZINC38149635 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068250 CCN(Cc1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C18H16ClF6NO/c1-2-26(11-12-6-4-3-5-7-12)15-9-8-13(10-14(15)19)16(27,17(20,21)22)18(23,24)25/h3-10,27H,2,11H2,1H3 JGXYOLQIFQNEAN-UHFFFAOYSA-N 50192134 2-(4-(benzyl(ethyl)amino)-3-chlorophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215663 Oxysterols receptor LXR-beta 3 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192134&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11683023 104075086 CHEMBL215663 ZINC38149642 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068251 CCN(Cc1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C18H16ClF6NO/c1-2-26(11-12-6-4-3-5-7-12)15-9-8-13(10-14(15)19)16(27,17(20,21)22)18(23,24)25/h3-10,27H,2,11H2,1H3 JGXYOLQIFQNEAN-UHFFFAOYSA-N 50192134 2-(4-(benzyl(ethyl)amino)-3-chlorophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215663 Oxysterols receptor LXR-beta 80 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192134&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11683023 104075086 CHEMBL215663 ZINC38149642 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068252 CCN(Cc1cscn1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C15H14F6N2OS/c1-2-23(7-11-8-25-9-22-11)12-5-3-10(4-6-12)13(24,14(16,17)18)15(19,20)21/h3-6,8-9,24H,2,7H2,1H3 DBCGQWBJSYJXSD-UHFFFAOYSA-N 50192142 1,1,1,3,3,3-hexafluoro-2-(4-(methyl(thiazol-4-ylmethyl)amino)phenyl)propan-2-ol::CHEMBL386174 Oxysterols receptor LXR-beta 50 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192142&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11617908 104075094 CHEMBL386174 ZINC35942802 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068254 CCN(C(COCC(=O)OC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H23F6NO4/c1-3-29(18(13-33-14-19(30)32-2)15-7-5-4-6-8-15)17-11-9-16(10-12-17)20(31,21(23,24)25)22(26,27)28/h4-12,18,31H,3,13-14H2,1-2H3 KPCMZDDOZHFXBR-UHFFFAOYSA-N 50192125 CHEMBL385052::methyl 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)acetate Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192125&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416842 104075077 CHEMBL385052 ZINC38149604 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068255 CCN(Cc1nc(oc1C)-c1cccc(c1)C(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H19F9N2O2/c1-3-34(17-9-7-15(8-10-17)20(35,22(27,28)29)23(30,31)32)12-18-13(2)36-19(33-18)14-5-4-6-16(11-14)21(24,25)26/h4-11,35H,3,12H2,1-2H3 DPUDSUKLVWJOHF-UHFFFAOYSA-N 50192136 2-(4-(ethyl((5-methyl-2-(3-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214867 Oxysterols receptor LXR-beta 60 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192136&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11584508 104075088 CHEMBL214867 ZINC38149637 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068256 CCN(C(COCCO)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H23F6NO3/c1-2-28(18(14-31-13-12-29)15-6-4-3-5-7-15)17-10-8-16(9-11-17)19(30,20(22,23)24)21(25,26)27/h3-11,18,29-30H,2,12-14H2,1H3 JALYOEQAGVCURF-UHFFFAOYSA-N 50192143 2-(4-(ethyl(2-(2-hydroxyethoxy)-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214915 Oxysterols receptor LXR-beta 32000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192143&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416843 104075095 CHEMBL214915 ZINC40568373 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068257 Cc1oc(nc1CN(CC(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)-c1cccc(c1)C(F)(F)F InChI=1S/C23H16F12N2O2/c1-12-17(36-18(39-12)13-3-2-4-15(9-13)21(27,28)29)10-37(11-19(24,25)26)16-7-5-14(6-8-16)20(38,22(30,31)32)23(33,34)35/h2-9,38H,10-11H2,1H3 QOUARJFUWURIGY-UHFFFAOYSA-N 50192126 1,1,1,3,3,3-hexafluoro-2-(4-(((5-methyl-2-(3-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)(2,2,2-trifluoroethyl)amino)phenyl)propan-2-ol::CHEMBL215042 Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192126&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11592304 104075078 CHEMBL215042 ZINC38149635 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068258 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068260 CCN(C(C(=O)N1CCOCC1)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H24F6N2O3/c1-2-31(18-10-8-17(9-11-18)21(33,22(24,25)26)23(27,28)29)19(16-6-4-3-5-7-16)20(32)30-12-14-34-15-13-30/h3-11,19,33H,2,12-15H2,1H3 CWFLKUZQTTZOMJ-UHFFFAOYSA-N 50192112 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-1-morpholino-2-phenylethanone::CHEMBL385544 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192112&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417045 104075064 CHEMBL385544 ZINC38149626 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068262 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(C)(C(=O)OC)c1ccccc1 InChI=1S/C21H21F6NO3/c1-4-28(18(2,17(29)31-3)14-8-6-5-7-9-14)16-12-10-15(11-13-16)19(30,20(22,23)24)21(25,26)27/h5-13,30H,4H2,1-3H3 GXMQHNQBWIJYMO-UHFFFAOYSA-N 50192138 CHEMBL215904::methyl 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylpropanoate Oxysterols receptor LXR-beta 8 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192138&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417046 104075090 CHEMBL215904 ZINC38149624 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068266 CCN(C(COCC(=O)N(C)C)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H26F6N2O3/c1-4-31(19(16-8-6-5-7-9-16)14-34-15-20(32)30(2)3)18-12-10-17(11-13-18)21(33,22(24,25)26)23(27,28)29/h5-13,19,33H,4,14-15H2,1-3H3 HSXPHPZTVBAFKE-UHFFFAOYSA-N 50192114 2-(2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylethoxy)-N,N-dimethylacetamide::CHEMBL215129 Oxysterols receptor LXR-beta 260 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192114&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417026 104075066 CHEMBL215129 ZINC38149602 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068267 CCN(C(COc1ccc(cc1)C(=O)OC)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C27H24ClF6NO4/c1-3-35(22-14-11-19(15-21(22)28)25(37,26(29,30)31)27(32,33)34)23(17-7-5-4-6-8-17)16-39-20-12-9-18(10-13-20)24(36)38-2/h4-15,23,37H,3,16H2,1-2H3 QGRQWRDAMFVQJV-UHFFFAOYSA-N 50192149 CHEMBL215130::methyl 4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)benzoate Oxysterols receptor LXR-beta 200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192149&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417027 104075101 CHEMBL215130 ZINC38149600 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068268 CCN(C(COc1ccc(CCC(O)=O)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H26ClF6NO4/c1-2-36(23-14-11-20(16-22(23)29)26(39,27(30,31)32)28(33,34)35)24(19-6-4-3-5-7-19)17-40-21-12-8-18(9-13-21)10-15-25(37)38/h3-9,11-14,16,24,39H,2,10,15,17H2,1H3,(H,37,38) FJTZZSUSVZOHJU-UHFFFAOYSA-N 50192115 3-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)propanoic acid::CHEMBL269442 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192115&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417028 104075067 CHEMBL269442 ZINC38149590 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068270 CCN(c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F)C(CC)(C(=O)OC)c1ccccc1 InChI=1S/C22H22ClF6NO3/c1-4-19(18(31)33-3,14-9-7-6-8-10-14)30(5-2)17-12-11-15(13-16(17)23)20(32,21(24,25)26)22(27,28)29/h6-13,32H,4-5H2,1-3H3 PDENOBIOQDVWAN-UHFFFAOYSA-N 50192153 CHEMBL215167::methyl 2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylbutanoate Oxysterols receptor LXR-beta 70 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192153&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416897 104075105 CHEMBL215167 ZINC38149620 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068272 CCN(C(COc1ccc(CC(=O)OC)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H26ClF6NO4/c1-3-36(23-14-11-20(16-22(23)29)26(38,27(30,31)32)28(33,34)35)24(19-7-5-4-6-8-19)17-40-21-12-9-18(10-13-21)15-25(37)39-2/h4-14,16,24,38H,3,15,17H2,1-2H3 DCMCTSPBOPLCIX-UHFFFAOYSA-N 50192154 CHEMBL215959::methyl 2-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)acetate Oxysterols receptor LXR-beta 30 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192154&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417052 104075106 CHEMBL215959 ZINC38149598 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068273 CCN(CCc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H19F6NO/c1-2-26(13-12-14-6-4-3-5-7-14)16-10-8-15(9-11-16)17(27,18(20,21)22)19(23,24)25/h3-11,27H,2,12-13H2,1H3 AHHXWYOHMGBGIR-UHFFFAOYSA-N 50192151 2-(4-(ethyl(phenethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215585 Oxysterols receptor LXR-beta 200 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192151&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11639715 104075103 CHEMBL215585 ZINC35983441 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068274 CCN(Cc1nc(oc1C)-c1cccc(c1)C(F)(F)F)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H18ClF9N2O2/c1-3-35(18-8-7-14(10-16(18)24)20(36,22(28,29)30)23(31,32)33)11-17-12(2)37-19(34-17)13-5-4-6-15(9-13)21(25,26)27/h4-10,36H,3,11H2,1-2H3 KIBPLVVEBAJZRG-UHFFFAOYSA-N 50192113 2-(3-chloro-4-(ethyl((5-methyl-2-(3-(trifluoromethyl)phenyl)oxazol-4-yl)methyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL383944 Oxysterols receptor LXR-beta 30 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192113&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11721039 104075065 CHEMBL383944 ZINC38149636 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068275 CCN(Cc1cccnc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H16F6N2O/c1-2-25(11-12-4-3-9-24-10-12)14-7-5-13(6-8-14)15(26,16(18,19)20)17(21,22)23/h3-10,26H,2,11H2,1H3 FWZYPDLJUKHKNM-UHFFFAOYSA-N 50192135 2-(4-(ethyl(pyridin-3-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL216055 Oxysterols receptor LXR-beta 2300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192135&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11559891 104075087 CHEMBL216055 ZINC35815010 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068276 CCN(C(COc1ccc(CCC(=O)OC)cc1)c1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C29H28ClF6NO4/c1-3-37(24-15-12-21(17-23(24)30)27(39,28(31,32)33)29(34,35)36)25(20-7-5-4-6-8-20)18-41-22-13-9-19(10-14-22)11-16-26(38)40-2/h4-10,12-15,17,25,39H,3,11,16,18H2,1-2H3 UUUSQFKWCMPEFI-UHFFFAOYSA-N 50192139 CHEMBL214687::methyl 3-(4-(2-((2-chloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)(ethyl)amino)-2-phenylethoxy)phenyl)propanoate Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192139&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44417072 104075091 CHEMBL214687 ZINC38149596 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068277 CCN(Cc1ccncc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H16F6N2O/c1-2-25(11-12-7-9-24-10-8-12)14-5-3-13(4-6-14)15(26,16(18,19)20)17(21,22)23/h3-10,26H,2,11H2,1H3 OLIMPPLJAGRECO-UHFFFAOYSA-N 50192111 2-(4-(ethyl(pyridin-4-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214275 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192111&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11696530 104075063 CHEMBL214275 ZINC38149641 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068278 CCN(Cc1ccccn1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H16F6N2O/c1-2-25(11-13-5-3-4-10-24-13)14-8-6-12(7-9-14)15(26,16(18,19)20)17(21,22)23/h3-10,26H,2,11H2,1H3 DKNJQXGMJWCWEW-UHFFFAOYSA-N 50192155 2-(4-(ethyl(pyridin-2-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214727 Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192155&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11632271 104075107 CHEMBL214727 ZINC35967335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068282 CCN(Cc1cscn1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C15H13ClF6N2OS/c1-2-24(6-10-7-26-8-23-10)12-4-3-9(5-11(12)16)13(25,14(17,18)19)15(20,21)22/h3-5,7-8,25H,2,6H2,1H3 OSFMRGZJJJLNPN-UHFFFAOYSA-N 50192148 2-(3-chloro-4-(ethyl(thiazol-4-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215036 Oxysterols receptor LXR-beta 160 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192148&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11633117 104075100 CHEMBL215036 ZINC35969236 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068283 CCN(Cc1ccccn1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H16F6N2O/c1-2-25(11-13-5-3-4-10-24-13)14-8-6-12(7-9-14)15(26,16(18,19)20)17(21,22)23/h3-10,26H,2,11H2,1H3 DKNJQXGMJWCWEW-UHFFFAOYSA-N 50192155 2-(4-(ethyl(pyridin-2-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL214727 Oxysterols receptor LXR-beta 460 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192155&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11632271 104075107 CHEMBL214727 ZINC35967335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068285 CCN(Cc1cscn1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C15H13ClF6N2OS/c1-2-24(6-10-7-26-8-23-10)12-4-3-9(5-11(12)16)13(25,14(17,18)19)15(20,21)22/h3-5,7-8,25H,2,6H2,1H3 OSFMRGZJJJLNPN-UHFFFAOYSA-N 50192148 2-(3-chloro-4-(ethyl(thiazol-4-ylmethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215036 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192148&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11633117 104075100 CHEMBL215036 ZINC35969236 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068286 CCN(C(COCc1ccccc1)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H25F6NO2/c1-2-33(22-15-13-21(14-16-22)24(34,25(27,28)29)26(30,31)32)23(20-11-7-4-8-12-20)18-35-17-19-9-5-3-6-10-19/h3-16,23,34H,2,17-18H2,1H3 DHVMIPXODCJNOG-UHFFFAOYSA-N 50192121 2-(4-((2-(benzyloxy)-1-phenylethyl)(ethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215647 Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192121&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416822 104075073 CHEMBL215647 ZINC38149606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068287 CCN(C(COC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H21F6NO2/c1-3-27(17(13-29-2)14-7-5-4-6-8-14)16-11-9-15(10-12-16)18(28,19(21,22)23)20(24,25)26/h4-12,17,28H,3,13H2,1-2H3 RTQPHBRRDAKJST-UHFFFAOYSA-N 50192123 2-(4-(ethyl(2-methoxy-1-phenylethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215598 Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192123&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416821 104075075 CHEMBL215598 ZINC38149608 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068288 CCN(C(C(=O)NC)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H20F6N2O2/c1-3-28(16(17(29)27-2)13-7-5-4-6-8-13)15-11-9-14(10-12-15)18(30,19(21,22)23)20(24,25)26/h4-12,16,30H,3H2,1-2H3,(H,27,29) HYMGUTROAWALBA-UHFFFAOYSA-N 50192110 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-N-methyl-2-phenylacetamide::CHEMBL215154 Oxysterols receptor LXR-beta 22000 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192110&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416819 104075062 CHEMBL215154 ZINC40568166 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068289 CCN(C(C(O)=O)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H17F6NO3/c1-2-26(15(16(27)28)12-6-4-3-5-7-12)14-10-8-13(9-11-14)17(29,18(20,21)22)19(23,24)25/h3-11,15,29H,2H2,1H3,(H,27,28) XBMKRWIORLIFDX-UHFFFAOYSA-N 50192129 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-2-phenylacetic acid::CHEMBL215327 Oxysterols receptor LXR-beta 13800 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192129&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416818 104075081 CHEMBL215327 ZINC38149631 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068290 Cc1oc(nc1CN(CC(F)(F)F)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)-c1cccc(Cl)c1 InChI=1S/C22H16ClF9N2O2/c1-12-17(33-18(36-12)13-3-2-4-15(23)9-13)10-34(11-19(24,25)26)16-7-5-14(6-8-16)20(35,21(27,28)29)22(30,31)32/h2-9,35H,10-11H2,1H3 XETFRQSXUSJFTQ-UHFFFAOYSA-N 50192128 2-(4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)methyl)(2,2,2-trifluoroethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL386603 Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192128&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11713676 104075080 CHEMBL386603 ZINC38149638 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068292 CCN(Cc1nc(oc1C)-c1cccc(Cl)c1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H18Cl2F6N2O2/c1-3-32(11-17-12(2)34-19(31-17)13-5-4-6-15(23)9-13)18-8-7-14(10-16(18)24)20(33,21(25,26)27)22(28,29)30/h4-10,33H,3,11H2,1-2H3 KNISWKWBHJJIBH-UHFFFAOYSA-N 50192137 2-(3-chloro-4-(((2-(3-chlorophenyl)-5-methyloxazol-4-yl)methyl)(ethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL215108 Oxysterols receptor LXR-beta 40 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192137&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11713433 104075089 CHEMBL215108 ZINC38149639 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068293 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(C)(C(=O)N(C)C)c1ccccc1 InChI=1S/C22H24F6N2O2/c1-5-30(19(2,18(31)29(3)4)15-9-7-6-8-10-15)17-13-11-16(12-14-17)20(32,21(23,24)25)22(26,27)28/h6-14,32H,5H2,1-4H3 OYDVTUOOJHLOCO-UHFFFAOYSA-N 50192127 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-N,N-dimethyl-2-phenylpropanamide::CHEMBL214948 Oxysterols receptor LXR-beta 60 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192127&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416914 104075079 CHEMBL214948 ZINC38149618 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068294 COC(=O)C1(CCCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)c1ccccc1 InChI=1S/C21H19F6NO3/c1-31-17(29)18(14-6-3-2-4-7-14)12-5-13-28(18)16-10-8-15(9-11-16)19(30,20(22,23)24)21(25,26)27/h2-4,6-11,30H,5,12-13H2,1H3 AVLKVXRYNFBRCI-UHFFFAOYSA-N 50192141 CHEMBL384298::methyl 1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-2-phenylpyrrolidine-2-carboxylate Oxysterols receptor LXR-beta 30 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192141&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416915 104075093 CHEMBL384298 ZINC38149616 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068298 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(C)(C(=O)N(C)C)c1ccccc1 InChI=1S/C22H24F6N2O2/c1-5-30(19(2,18(31)29(3)4)15-9-7-6-8-10-15)17-13-11-16(12-14-17)20(32,21(23,24)25)22(26,27)28/h6-14,32H,5H2,1-4H3 OYDVTUOOJHLOCO-UHFFFAOYSA-N 50192127 2-(ethyl(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)amino)-N,N-dimethyl-2-phenylpropanamide::CHEMBL214948 Oxysterols receptor LXR-beta 70 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192127&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416914 104075079 CHEMBL214948 ZINC38149618 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50068299 COC(=O)C1(CCCN1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)c1ccccc1 InChI=1S/C21H19F6NO3/c1-31-17(29)18(14-6-3-2-4-7-14)12-5-13-28(18)16-10-8-15(9-11-16)19(30,20(22,23)24)21(25,26)27/h2-4,6-11,30H,5,12-13H2,1H3 AVLKVXRYNFBRCI-UHFFFAOYSA-N 50192141 CHEMBL384298::methyl 1-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-2-phenylpyrrolidine-2-carboxylate Oxysterols receptor LXR-beta 40 ChEMBL 10.1016/j.bmcl.2006.06.081 10.7270/Q2HD7V80 16876993 Panday, N; Benz, J; Blum-Kaelin, D; Bourgeaux, V; Dehmlow, H; Hartman, P; Kuhn, B; Ratni, H; Warot, X; Wright, MB F. Hoffmann-La Roche Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192141&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44416915 104075093 CHEMBL384298 ZINC38149616 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071428 CCCCN(Cc1cc(Cl)c(O)c(OC)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H22ClF6NO3/c1-3-4-9-29(12-13-10-16(22)18(30)17(11-13)32-2)15-7-5-14(6-8-15)19(31,20(23,24)25)21(26,27)28/h5-8,10-11,30-31H,3-4,9,12H2,1-2H3 ZFFZFXPMACXICV-UHFFFAOYSA-N 50252938 4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-2-chloro-6-methoxyphenol::CHEMBL524014 Oxysterols receptor LXR-beta 45 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252938&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049539 104105638 CHEMBL524014 ZINC34946799 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071429 CCCCN(Cc1cc(Cl)cc(Cl)c1O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H19Cl2F6NO2/c1-2-3-8-29(11-12-9-14(21)10-16(22)17(12)30)15-6-4-13(5-7-15)18(31,19(23,24)25)20(26,27)28/h4-7,9-10,30-31H,2-3,8,11H2,1H3 VBTYDVKMVDEHCS-UHFFFAOYSA-N 50252906 2-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-4,6-dichlorophenol::CHEMBL492243 Oxysterols receptor LXR-beta 290 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252906&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049478 104105617 CHEMBL492243 ZINC34946703 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071430 OC(c1ccc(cc1)N(Cc1ccccc1)Cc1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C23H19F6NO/c24-22(25,26)21(31,23(27,28)29)19-11-13-20(14-12-19)30(15-17-7-3-1-4-8-17)16-18-9-5-2-6-10-18/h1-14,31H,15-16H2 ICESJPMAGXLVST-UHFFFAOYSA-N 50252690 2-(4-(dibenzylamino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL522039 Oxysterols receptor LXR-beta 175 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252690&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1734080 104105439 CHEMBL522039 ZINC02072446 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071431 CCCCN(Cc1ccncc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H20F6N2O/c1-2-3-12-27(13-14-8-10-26-11-9-14)16-6-4-15(5-7-16)17(28,18(20,21)22)19(23,24)25/h4-11,28H,2-3,12-13H2,1H3 OHMHEOQEFHVRNC-UHFFFAOYSA-N 50252850 2-{4-[Butyl(pyridin-4-ylmethyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL494073 Oxysterols receptor LXR-beta 25 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252850&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049475 104105572 CHEMBL494073 ZINC34946698 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071432 CCCCN(Cc1ccccn1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H20F6N2O/c1-2-3-12-27(13-15-6-4-5-11-26-15)16-9-7-14(8-10-16)17(28,18(20,21)22)19(23,24)25/h4-11,28H,2-3,12-13H2,1H3 ZFAPBUWDFPNGAU-UHFFFAOYSA-N 50252817 2-{4-[Butyl(pyridin-2-ylmethyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL494674 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252817&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049407 104105548 CHEMBL494674 ZINC34946593 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071433 CCCCN(Cc1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H19Cl2F6NO/c1-2-3-8-29(12-13-9-15(21)11-16(22)10-13)17-6-4-14(5-7-17)18(30,19(23,24)25)20(26,27)28/h4-7,9-11,30H,2-3,8,12H2,1H3 YBGOHLSRWRGQOX-UHFFFAOYSA-N 50252941 2-{4-[Butyl(3,5-dichlorobenzyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL493242 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252941&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049540 104105641 CHEMBL493242 ZINC34946801 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071434 CCCCN(Cc1cc(Cl)c(O)c(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H19Cl2F6NO2/c1-2-3-8-29(11-12-9-15(21)17(30)16(22)10-12)14-6-4-13(5-7-14)18(31,19(23,24)25)20(26,27)28/h4-7,9-10,30-31H,2-3,8,11H2,1H3 TYYLMKBOWXDDCT-UHFFFAOYSA-N 50252940 4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-2,6-dichlorophenol::CHEMBL493241::GSK-9772 Oxysterols receptor LXR-beta 3000 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252940&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049480 104105640 CHEMBL493241 ZINC34946707 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071435 CCCCN(Cc1cc(Cl)c(OC)c(OC)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H24ClF6NO3/c1-4-5-10-30(13-14-11-17(23)19(33-3)18(12-14)32-2)16-8-6-15(7-9-16)20(31,21(24,25)26)22(27,28)29/h6-9,11-12,31H,4-5,10,13H2,1-3H3 QKFWYOZIIUVZRC-UHFFFAOYSA-N 50252939 2-[4-(Butyl{[3-chloro-4,5-bis(methyloxy)phenyl]methyl}amino)phenyl]-1,1,1,3,3,3-hexafluoro-2-propanol::2-{4-[butyl(3-chloro-4,5-dimethoxybenzyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL493033 Oxysterols receptor LXR-beta 25 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search LO2 3FAL 11352536 104105639 CHEMBL493033 ZINC13982505 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071436 CCCCN(Cc1cc(OC(F)(F)F)ccc1O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H20F9NO3/c1-2-3-10-31(12-13-11-16(8-9-17(13)32)34-21(28,29)30)15-6-4-14(5-7-15)18(33,19(22,23)24)20(25,26)27/h4-9,11,32-33H,2-3,10,12H2,1H3 GUMNJMLKNVBADL-UHFFFAOYSA-N 50252905 2-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-4-(trifluoromethoxy)phenol::CHEMBL493468 Oxysterols receptor LXR-beta 165 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252905&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049537 104105616 CHEMBL493468 ZINC49881595 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071437 CCCCN(Cc1cccc(CCO)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C22H25F6NO2/c1-2-3-12-29(15-17-6-4-5-16(14-17)11-13-30)19-9-7-18(8-10-19)20(31,21(23,24)25)22(26,27)28/h4-10,14,30-31H,2-3,11-13,15H2,1H3 YGEIBYBALYPULP-UHFFFAOYSA-N 50252816 2-(4-{Butyl[3-(2-hydroxyethoxy)benzyl]amino}phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL494471 Oxysterols receptor LXR-beta 15 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252816&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44568830 104105547 CHEMBL494471 ZINC40952656 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071438 CCCCN(Cc1cc(Cl)c(O)c(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H19Cl2F6NO2/c1-2-3-8-29(11-12-9-15(21)17(30)16(22)10-12)14-6-4-13(5-7-14)18(31,19(23,24)25)20(26,27)28/h4-7,9-10,30-31H,2-3,8,11H2,1H3 TYYLMKBOWXDDCT-UHFFFAOYSA-N 50252940 4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-2,6-dichlorophenol::CHEMBL493241::GSK-9772 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252940&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049480 104105640 CHEMBL493241 ZINC34946707 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071439 CCCCN(Cc1cc(Cl)c(OC)c(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C21H21Cl2F6NO2/c1-3-4-9-30(12-13-10-16(22)18(32-2)17(23)11-13)15-7-5-14(6-8-15)19(31,20(24,25)26)21(27,28)29/h5-8,10-11,31H,3-4,9,12H2,1-2H3 SOBZXBIGGHGORD-UHFFFAOYSA-N 50252967 2-{4-[Butyl(3,5-dichloro-4-methoxybenzyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL492421 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252967&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049541 104105658 CHEMBL492421 ZINC34946802 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071441 CCCCN(Cc1ccccc1O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H21F6NO2/c1-2-3-12-27(13-14-6-4-5-7-17(14)28)16-10-8-15(9-11-16)18(29,19(21,22)23)20(24,25)26/h4-11,28-29H,2-3,12-13H2,1H3 XGQYNNAEFXRDTB-UHFFFAOYSA-N 50252851 2-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]phenol::CHEMBL492637 Oxysterols receptor LXR-beta 40 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252851&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049476 104105573 CHEMBL492637 ZINC34946700 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071442 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071443 CCCCN(Cc1ccc(O)cc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H21F6NO2/c1-2-3-12-27(13-14-4-10-17(28)11-5-14)16-8-6-15(7-9-16)18(29,19(21,22)23)20(24,25)26/h4-11,28-29H,2-3,12-13H2,1H3 PZIHTPUCJUDWOV-UHFFFAOYSA-N 50252853 4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]phenol::CHEMBL492845 Oxysterols receptor LXR-beta 740 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252853&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 15953841 104105575 CHEMBL492845 ZINC34809201 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071444 CCCCN(Cc1cccc(O)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H21F6NO2/c1-2-3-11-27(13-14-5-4-6-17(28)12-14)16-9-7-15(8-10-16)18(29,19(21,22)23)20(24,25)26/h4-10,12,28-29H,2-3,11,13H2,1H3 ACIHLXUCCJMZLS-UHFFFAOYSA-N 50252852 3-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]phenol::CHEMBL492844 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252852&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049474 104105574 CHEMBL492844 ZINC34946696 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071445 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071446 CCCCN(Cc1cccc(F)c1O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H20F7NO2/c1-2-3-11-28(12-13-5-4-6-16(21)17(13)29)15-9-7-14(8-10-15)18(30,19(22,23)24)20(25,26)27/h4-10,29-30H,2-3,11-12H2,1H3 UKJHXWDCHRPIEJ-UHFFFAOYSA-N 50252854 2-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-6-fluorophenol::CHEMBL522159 Oxysterols receptor LXR-beta 120 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252854&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049477 104105576 CHEMBL522159 ZINC34946702 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071447 CCCCN(Cc1cc(Cl)ccc1O)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H20ClF6NO2/c1-2-3-10-28(12-13-11-15(21)6-9-17(13)29)16-7-4-14(5-8-16)18(30,19(22,23)24)20(25,26)27/h4-9,11,29-30H,2-3,10,12H2,1H3 KJVVCZBQRYYDRM-UHFFFAOYSA-N 50252907 2-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-4-chlorophenol::CHEMBL521981 Oxysterols receptor LXR-beta 115 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252907&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049538 104105618 CHEMBL521981 ZINC34946797 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071448 CCCCN(Cc1ccc(O)c(Cl)c1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H20ClF6NO2/c1-2-3-10-28(12-13-4-9-17(29)16(21)11-13)15-7-5-14(6-8-15)18(30,19(22,23)24)20(25,26)27/h4-9,11,29-30H,2-3,10,12H2,1H3 WOBTZYHUGUOYFA-UHFFFAOYSA-N 50252908 4-[(Butyl{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}amino)methyl]-2-chlorophenol::CHEMBL492440 Oxysterols receptor LXR-beta 50 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252908&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049479 104105619 CHEMBL492440 ZINC34946705 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071449 CCCCN(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H21F6NO/c1-2-3-13-27(14-15-7-5-4-6-8-15)17-11-9-16(10-12-17)18(28,19(21,22)23)20(24,25)26/h4-12,28H,2-3,13-14H2,1H3 FXKCJMNHVGXENM-UHFFFAOYSA-N 50252815 2-{4-[Benzyl(butyl)amino]phenyl}-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL494676 Oxysterols receptor LXR-beta 40 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252815&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25107513 104105546 CHEMBL494676 ZINC40952669 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50071450 CN(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H15F6NO/c1-24(11-12-5-3-2-4-6-12)14-9-7-13(8-10-14)15(25,16(18,19)20)17(21,22)23/h2-10,25H,11H2,1H3 WPDYLZPHLQWKCW-UHFFFAOYSA-N 50252814 1,1,1,3,3,3-Hexafluoro-2-{4-[methyl(phenylmethyl)amino]phenyl}-2-propanol::CHEMBL495494 Oxysterols receptor LXR-beta 170 ChEMBL 10.1021/jm800612u 10.7270/Q28052FN 18800767 Chao, EY; Caravella, JA; Watson, MA; Campobasso, N; Ghisletti, S; Billin, AN; Galardi, C; Wang, P; Laffitte, BA; Iannone, MA; Goodwin, BJ; Nichols, JA; Parks, DJ; Stewart, E; Wiethe, RW; Williams, SP; Smallwood, A; Pearce, KH; Glass, CK; Willson, TM; Zuercher, WJ; Collins, JL GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252814&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16049406 104105545 CHEMBL495494 ZINC34946592 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092334 CC(C)CN(Cc1ccc(s1)-c1cccc(c1)S(C)(=O)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C23H27NO4S3/c1-18(2)15-24(31(27,28)17-19-8-5-4-6-9-19)16-21-12-13-23(29-21)20-10-7-11-22(14-20)30(3,25)26/h4-14,18H,15-17H2,1-3H3 PDAASAKPBNZZQB-UHFFFAOYSA-N 50012122 CHEMBL3263695 Oxysterols receptor LXR-beta 450 ChEMBL 10.1016/j.bmcl.2014.03.038 10.7270/Q29K4CSN 24685544 Fauber, BP; René, O; Burton, B; Everett, C; Gobbi, A; Hawkins, J; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012122&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25234324 242058048 CHEMBL3263695 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092355 CC(C)CN(Cc1ccc(s1)-c1cccc(c1)S(C)(=O)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C23H27NO4S3/c1-18(2)15-24(31(27,28)17-19-8-5-4-6-9-19)16-21-12-13-23(29-21)20-10-7-11-22(14-20)30(3,25)26/h4-14,18H,15-17H2,1-3H3 PDAASAKPBNZZQB-UHFFFAOYSA-N 50012122 CHEMBL3263695 Oxysterols receptor LXR-beta 1900 ChEMBL 10.1016/j.bmcl.2014.03.038 10.7270/Q29K4CSN 24685544 Fauber, BP; René, O; Burton, B; Everett, C; Gobbi, A; Hawkins, J; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012122&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25234324 242058048 CHEMBL3263695 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092356 CC(C)CN(Cc1ccc(s1)-c1ccc(cc1)S(C)(=O)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C23H27NO4S3/c1-18(2)15-24(31(27,28)17-19-7-5-4-6-8-19)16-21-11-14-23(29-21)20-9-12-22(13-10-20)30(3,25)26/h4-14,18H,15-17H2,1-3H3 RXMHSSANSKRGOG-UHFFFAOYSA-N 50012123 CHEMBL3263696 Oxysterols receptor LXR-beta 3900 ChEMBL 10.1016/j.bmcl.2014.03.038 10.7270/Q29K4CSN 24685544 Fauber, BP; René, O; Burton, B; Everett, C; Gobbi, A; Hawkins, J; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012123&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 39K 4QM0 77620538 242058049 CHEMBL3263696 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092357 CC(C)CN(Cc1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C25H29NO4S2/c1-20(2)17-26(32(29,30)19-22-7-5-4-6-8-22)18-21-9-11-23(12-10-21)24-13-15-25(16-14-24)31(3,27)28/h4-16,20H,17-19H2,1-3H3 PLZDXNPMOQHWFC-UHFFFAOYSA-N 50012130 CHEMBL3263710 Oxysterols receptor LXR-beta 2500 ChEMBL 10.1016/j.bmcl.2014.03.038 10.7270/Q29K4CSN 24685544 Fauber, BP; René, O; Burton, B; Everett, C; Gobbi, A; Hawkins, J; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012130&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71622396 242058056 CHEMBL3263710 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092358 CC(C)CN(Cc1ccc(cc1)-c1ccc(NS(C)(=O)=O)cc1)S(=O)(=O)Cc1ccccc1 InChI=1S/C25H30N2O4S2/c1-20(2)17-27(33(30,31)19-22-7-5-4-6-8-22)18-21-9-11-23(12-10-21)24-13-15-25(16-14-24)26-32(3,28)29/h4-16,20,26H,17-19H2,1-3H3 BETLCLLQVPJRSB-UHFFFAOYSA-N 50012124 CHEMBL3263714 Oxysterols receptor LXR-beta 3800 ChEMBL 10.1016/j.bmcl.2014.03.038 10.7270/Q29K4CSN 24685544 Fauber, BP; René, O; Burton, B; Everett, C; Gobbi, A; Hawkins, J; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012124&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89665055 242058050 CHEMBL3263714 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092359 CC(C)CN(Cc1ccc(cc1)-c1ccc(cc1)C(N)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C25H28N2O3S/c1-19(2)16-27(31(29,30)18-21-6-4-3-5-7-21)17-20-8-10-22(11-9-20)23-12-14-24(15-13-23)25(26)28/h3-15,19H,16-18H2,1-2H3,(H2,26,28) VQDAIDJRXUVFEV-UHFFFAOYSA-N 50012126 CHEMBL3263716 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.03.038 10.7270/Q29K4CSN 24685544 Fauber, BP; René, O; Burton, B; Everett, C; Gobbi, A; Hawkins, J; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012126&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 86302482 242058052 CHEMBL3263716 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092827 CCCCn1c2ccc(cc2c2cc(Cl)ccc2c1=O)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C20H16ClF6NO2/c1-2-3-8-28-16-7-4-11(18(30,19(22,23)24)20(25,26)27)9-15(16)14-10-12(21)5-6-13(14)17(28)29/h4-7,9-10,30H,2-3,8H2,1H3 KBOKCQLFWLAHHN-UHFFFAOYSA-N 50012275 CHEMBL3260000 Oxysterols receptor LXR-beta 680 ChEMBL 10.1016/j.bmc.2014.03.007 10.7270/Q28K7BN8 24702856 Nishiyama, Y; Nakamura, M; Misawa, T; Nakagomi, M; Makishima, M; Ishikawa, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012275&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 78319220 103924564 CHEMBL3260000 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50092829 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 120 ChEMBL 10.1016/j.bmc.2014.03.007 10.7270/Q28K7BN8 24702856 Nishiyama, Y; Nakamura, M; Misawa, T; Nakagomi, M; Makishima, M; Ishikawa, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131021 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCc1ccccc1 InChI=1S/C24H28O3/c1-23-13-6-14-24(2,22(26)27-16-17-7-4-3-5-8-17)21(23)12-10-18-9-11-19(25)15-20(18)23/h3-5,7-9,11,15,21,25H,6,10,12-14,16H2,1-2H3/t21-,23-,24+/m1/s1 KMEJLXYWBXIHMZ-JRFVFWCSSA-N 50172196 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid benzyl ester::CHEMBL427183 Oxysterols receptor LXR-beta >15000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172196&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403617 104058325 CHEMBL427183 ZINC28525730 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131022 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NCC1(CCCCC1)c1ccccc1 InChI=1S/C30H39NO/c1-28-18-11-19-29(2,26(28)17-16-23-12-7-8-15-25(23)28)27(32)31-22-30(20-9-4-10-21-30)24-13-5-3-6-14-24/h3,5-8,12-15,26H,4,9-11,16-22H2,1-2H3,(H,31,32)/t26-,28-,29+/m1/s1 PXRKUDZYCJZQBB-CMYDWJSCSA-N 50172186 (1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-phenyl-cyclohexylmethyl)-amide::CHEMBL194353 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172186&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10342621 104058315 CHEMBL194353 ZINC28526539 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131023 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NCC1(CCCCC1)c1ccccc1 InChI=1S/C30H39NO2/c1-28-16-9-17-29(2,26(28)15-13-22-12-14-24(32)20-25(22)28)27(33)31-21-30(18-7-4-8-19-30)23-10-5-3-6-11-23/h3,5-6,10-12,14,20,26,32H,4,7-9,13,15-19,21H2,1-2H3,(H,31,33)/t26-,28-,29+/m1/s1 JEXLPLDYRYUENX-CMYDWJSCSA-N 50172204 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-phenyl-cyclohexylmethyl)-amide::CHEMBL372612 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172204&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10433666 104058333 CHEMBL372612 ZINC28526538 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131024 C[C@@H]1[C@H]2C[C@@H](C[C@H]1NC(=O)[C@@]1(C)CCC[C@@]3(C)[C@H]1CCc1ccc(O)cc31)C2(C)C InChI=1S/C27H39NO2/c1-16-20-13-18(25(20,2)3)14-22(16)28-24(30)27(5)12-6-11-26(4)21-15-19(29)9-7-17(21)8-10-23(26)27/h7,9,15-16,18,20,22-23,29H,6,8,10-14H2,1-5H3,(H,28,30)/t16-,18+,20-,22-,23-,26-,27+/m1/s1 AWFKUZKMHLKRBA-LRZFQQLUSA-N 50172190 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1R,2R,3R,5S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl)-amide::CHEMBL382942 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172190&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403645 104058319 CHEMBL382942 ZINC28527081 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131025 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)CC(=O)C12CC3CC(CC(C3)C1)C2 InChI=1S/C29H38O2/c1-27-10-5-11-28(2,24(27)9-8-22-6-3-4-7-23(22)27)25(30)15-26(31)29-16-19-12-20(17-29)14-21(13-19)18-29/h3-4,6-7,19-21,24H,5,8-18H2,1-2H3/t19?,20?,21?,24-,27-,28+,29?/m1/s1 FYECAKXFUFMVEN-RRWSZUJYSA-N 50172187 1-Adamantan-1-yl-3-((1S,4aS,10aR)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-propane-1,3-dione::CHEMBL194866 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172187&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403589 104058316 CHEMBL194866 ZINC28526370 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131028 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC12CC3CC(CC(C3)C1)C2 InChI=1S/C27H37NO2/c1-25-8-3-9-26(2,23(25)7-5-20-4-6-21(29)13-22(20)25)24(30)28-27-14-17-10-18(15-27)12-19(11-17)16-27/h4,6,13,17-19,23,29H,3,5,7-12,14-16H2,1-2H3,(H,28,30)/t17?,18?,19?,23-,25-,26+,27?/m1/s1 YYIDRXGXLIOEDJ-DXYQEDLISA-N 50172200 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid adamantan-1-ylamide::CHEMBL199255 Oxysterols receptor LXR-beta 220 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172200&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10431545 104058329 CHEMBL199255 ZINC28527083 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131031 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H43NO4/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(36)19-25(21)31)29(38)35-30(39)34(4)18-6-16-32(2)26-20-24(37)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,36-37H,5-6,9-10,13-18H2,1-4H3,(H,35,38,39)/t27-,28-,31-,32-,33+,34?/m1/s1 ASTLYMNMTDERKI-IMUKZWIGSA-N 50167697 (4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::(4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL365544 Oxysterols receptor LXR-beta 1 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400748 104052913 CHEMBL365544 ZINC28520935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131032 CC(NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C12CC3CC(CC(C3)C1)C2 InChI=1S/C29H41NO2/c1-18(29-15-19-11-20(16-29)13-21(12-19)17-29)30-26(32)28(3)10-4-9-27(2)24-14-23(31)7-5-22(24)6-8-25(27)28/h5,7,14,18-21,25,31H,4,6,8-13,15-17H2,1-3H3,(H,30,32)/t18?,19?,20?,21?,25-,27-,28+,29?/m1/s1 AEORYXMWRGDQDS-LIFQUHLFSA-N 50172206 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-adamantan-1-yl-ethyl)-amide::CHEMBL371990 Oxysterols receptor LXR-beta 180 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172206&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10252443 104058335 CHEMBL371990 ZINC28525862 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131033 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NC(=O)C1(CCCCC1)c1ccccc1 InChI=1S/C30H37NO2/c1-28-18-11-19-29(2,25(28)17-16-22-12-7-8-15-24(22)28)26(32)31-27(33)30(20-9-4-10-21-30)23-13-5-3-6-14-23/h3,5-8,12-15,25H,4,9-11,16-21H2,1-2H3,(H,31,32,33)/t25-,28-,29+/m1/s1 RFGMOPNIYZVCFS-ZJGIAAPESA-N 50172199 1-Phenyl-cyclohexanecarboxylic acid ((1S,4aS,10aR)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL194573 Oxysterols receptor LXR-beta 120 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172199&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403571 104058328 CHEMBL194573 ZINC28525805 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131034 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NC(=O)C12CC3CC(CC(C3)C1)C2 InChI=1S/C28H37NO2/c1-26-10-5-11-27(2,23(26)9-8-21-6-3-4-7-22(21)26)24(30)29-25(31)28-15-18-12-19(16-28)14-20(13-18)17-28/h3-4,6-7,18-20,23H,5,8-17H2,1-2H3,(H,29,30,31)/t18?,19?,20?,23-,26-,27+,28?/m1/s1 IEPOYBLCAUUPJP-GDCRIOODSA-N 50172207 Adamantane-1-carboxylic acid ((1S,4aS,10aR)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL194679 Oxysterols receptor LXR-beta 290 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172207&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403570 104058336 CHEMBL194679 ZINC28526118 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131038 CC(CNC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccccc21)(c1ccccc1)c1ccccc1 InChI=1S/C32H37NO/c1-30-21-12-22-31(2,28(30)20-19-24-13-10-11-18-27(24)30)29(34)33-23-32(3,25-14-6-4-7-15-25)26-16-8-5-9-17-26/h4-11,13-18,28H,12,19-23H2,1-3H3,(H,33,34)/t28-,30-,31+/m1/s1 FCQLLWXAPLXYQV-HQMADOEBSA-N 50172203 (1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (2,2-diphenyl-propyl)-amide::CHEMBL365750 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172203&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403557 104058332 CHEMBL365750 ZINC28526141 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131039 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCC(CC1)c1ccccc1 InChI=1S/C28H35NO/c1-27-17-8-18-28(2,25(27)14-13-23-11-6-7-12-24(23)27)26(30)29-19-15-22(16-20-29)21-9-4-3-5-10-21/h3-7,9-12,22,25H,8,13-20H2,1-2H3/t25-,27-,28+/m1/s1 ZJPIFOVRFHBVNC-KZQOYIJHSA-N 50172195 ((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-(4-phenyl-piperidin-1-yl)-methanone::CHEMBL194733 Oxysterols receptor LXR-beta 70 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172195&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403558 104058324 CHEMBL194733 ZINC28526142 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131041 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC1C2CC3CC(C2)CC1C3 InChI=1S/C27H37NO2/c1-26-8-3-9-27(2,23(26)7-5-18-4-6-21(29)15-22(18)26)25(30)28-24-19-11-16-10-17(13-19)14-20(24)12-16/h4,6,15-17,19-20,23-24,29H,3,5,7-14H2,1-2H3,(H,28,30)/t16?,17?,19?,20?,23-,24?,26-,27+/m1/s1 GBNHOQWDXVLAFY-SRYDNDORSA-N 50172188 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid adamantan-2-ylamide::CHEMBL194409 Oxysterols receptor LXR-beta 3800 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172188&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10001458 104058317 CHEMBL194409 ZINC28526481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131042 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC1C2CC3CC(C2)CC1C3 InChI=1S/C27H37NO2/c1-26-8-3-9-27(2,23(26)7-5-18-4-6-21(29)15-22(18)26)25(30)28-24-19-11-16-10-17(13-19)14-20(24)12-16/h4,6,15-17,19-20,23-24,29H,3,5,7-14H2,1-2H3,(H,28,30)/t16?,17?,19?,20?,23-,24?,26-,27+/m1/s1 GBNHOQWDXVLAFY-SRYDNDORSA-N 50172188 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid adamantan-2-ylamide::CHEMBL194409 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172188&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10001458 104058317 CHEMBL194409 ZINC28526481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131045 CC1(C)C2CC1C(CC2)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C26H37NO2/c1-24(2)17-8-10-21(20(24)14-17)27-23(29)26(4)13-5-12-25(3)19-15-18(28)9-6-16(19)7-11-22(25)26/h6,9,15,17,20-22,28H,5,7-8,10-14H2,1-4H3,(H,27,29)/t17?,20?,21?,22-,25-,26+/m1/s1 GREUENDQALGMMV-XSYRNFCJSA-N 50172197 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (6,6-dimethyl-bicyclo[3.1.1]hept-2-yl)-amide::CHEMBL197522 Oxysterols receptor LXR-beta 310 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172197&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403639 104058326 CHEMBL197522 ZINC28525864 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131046 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)CC(=O)C12CC3CC(CC(C3)C1)C2 InChI=1S/C29H38O2/c1-27-10-5-11-28(2,24(27)9-8-22-6-3-4-7-23(22)27)25(30)15-26(31)29-16-19-12-20(17-29)14-21(13-19)18-29/h3-4,6-7,19-21,24H,5,8-18H2,1-2H3/t19?,20?,21?,24-,27-,28+,29?/m1/s1 FYECAKXFUFMVEN-RRWSZUJYSA-N 50172187 1-Adamantan-1-yl-3-((1S,4aS,10aR)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-propane-1,3-dione::CHEMBL194866 Oxysterols receptor LXR-beta 1010 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172187&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403589 104058316 CHEMBL194866 ZINC28526370 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131047 C[C@@H]1[C@H]2C[C@@H](C[C@H]1NC(=O)[C@@]1(C)CCC[C@@]3(C)[C@H]1CCc1ccc(O)cc31)C2(C)C InChI=1S/C27H39NO2/c1-16-20-13-18(25(20,2)3)14-22(16)28-24(30)27(5)12-6-11-26(4)21-15-19(29)9-7-17(21)8-10-23(26)27/h7,9,15-16,18,20,22-23,29H,6,8,10-14H2,1-5H3,(H,28,30)/t16-,18+,20-,22-,23-,26-,27+/m1/s1 AWFKUZKMHLKRBA-LRZFQQLUSA-N 50172190 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1R,2R,3R,5S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl)-amide::CHEMBL382942 Oxysterols receptor LXR-beta 200 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172190&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403645 104058319 CHEMBL382942 ZINC28527081 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131048 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC12CC3CC(CC(C3)C1)C2 InChI=1S/C27H37NO2/c1-25-8-3-9-26(2,23(25)7-5-20-4-6-21(29)13-22(20)25)24(30)28-27-14-17-10-18(15-27)12-19(11-17)16-27/h4,6,13,17-19,23,29H,3,5,7-12,14-16H2,1-2H3,(H,28,30)/t17?,18?,19?,23-,25-,26+,27?/m1/s1 YYIDRXGXLIOEDJ-DXYQEDLISA-N 50172200 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid adamantan-1-ylamide::CHEMBL199255 Oxysterols receptor LXR-beta 170 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172200&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10431545 104058329 CHEMBL199255 ZINC28527083 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131052 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NCC1(CCCCC1)c1ccccc1 InChI=1S/C30H39NO/c1-28-18-11-19-29(2,26(28)17-16-23-12-7-8-15-25(23)28)27(32)31-22-30(20-9-4-10-21-30)24-13-5-3-6-14-24/h3,5-8,12-15,26H,4,9-11,16-22H2,1-2H3,(H,31,32)/t26-,28-,29+/m1/s1 PXRKUDZYCJZQBB-CMYDWJSCSA-N 50172186 (1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-phenyl-cyclohexylmethyl)-amide::CHEMBL194353 Oxysterols receptor LXR-beta 130 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172186&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10342621 104058315 CHEMBL194353 ZINC28526539 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131053 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCc1ccccc1 InChI=1S/C24H28O3/c1-23-13-6-14-24(2,22(26)27-16-17-7-4-3-5-8-17)21(23)12-10-18-9-11-19(25)15-20(18)23/h3-5,7-9,11,15,21,25H,6,10,12-14,16H2,1-2H3/t21-,23-,24+/m1/s1 KMEJLXYWBXIHMZ-JRFVFWCSSA-N 50172196 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid benzyl ester::CHEMBL427183 Oxysterols receptor LXR-beta 2900 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172196&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403617 104058325 CHEMBL427183 ZINC28525730 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131054 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCCC=C InChI=1S/C21H28O3/c1-4-5-13-24-19(23)21(3)12-6-11-20(2)17-14-16(22)9-7-15(17)8-10-18(20)21/h4,7,9,14,18,22H,1,5-6,8,10-13H2,2-3H3/t18-,20-,21+/m1/s1 DIWGSLNGJZKMCD-NRSPTQNISA-N 50172194 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid but-3-enyl ester::CHEMBL194192 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172194&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403620 104058323 CHEMBL194192 ZINC28526611 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131055 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCC=C InChI=1S/C20H26O3/c1-4-12-23-18(22)20(3)11-5-10-19(2)16-13-15(21)8-6-14(16)7-9-17(19)20/h4,6,8,13,17,21H,1,5,7,9-12H2,2-3H3/t17-,19-,20+/m1/s1 WJRBGHXSPIFNBU-RLLQIKCJSA-N 50172201 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid allyl ester::CHEMBL196106 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172201&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403619 104058330 CHEMBL196106 ZINC28526610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131056 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NCC1(CCCCC1)c1ccccc1 InChI=1S/C30H39NO2/c1-28-16-9-17-29(2,26(28)15-13-22-12-14-24(32)20-25(22)28)27(33)31-21-30(18-7-4-8-19-30)23-10-5-3-6-11-23/h3,5-6,10-12,14,20,26,32H,4,7-9,13,15-19,21H2,1-2H3,(H,31,33)/t26-,28-,29+/m1/s1 JEXLPLDYRYUENX-CMYDWJSCSA-N 50172204 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-phenyl-cyclohexylmethyl)-amide::CHEMBL372612 Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172204&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10433666 104058333 CHEMBL372612 ZINC28526538 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131057 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCC=C InChI=1S/C20H26O3/c1-4-12-23-18(22)20(3)11-5-10-19(2)16-13-15(21)8-6-14(16)7-9-17(19)20/h4,6,8,13,17,21H,1,5,7,9-12H2,2-3H3/t17-,19-,20+/m1/s1 WJRBGHXSPIFNBU-RLLQIKCJSA-N 50172201 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid allyl ester::CHEMBL196106 Oxysterols receptor LXR-beta >15000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172201&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403619 104058330 CHEMBL196106 ZINC28526610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131058 CC(=O)Oc1ccc2CC[C@H]3C(C)(CCC[C@]3(C)c2c1)C(=O)OC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(OC(C)=O)cc21 InChI=1S/C38H46O7/c1-23(39)43-27-13-9-25-11-15-31-35(3,29(25)21-27)17-7-19-37(31,5)33(41)45-34(42)38(6)20-8-18-36(4)30-22-28(44-24(2)40)14-10-26(30)12-16-32(36)38/h9-10,13-14,21-22,31-32H,7-8,11-12,15-20H2,1-6H3/t31-,32-,35-,36-,37+,38?/m1/s1 OUJQRQRBNRGQTC-PWAHEJKMSA-N 50167694 2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-triene-6-carboxylic anhydride::2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL191965 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400646 104052910 CHEMBL191965 ZINC38149326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131061 CCOC(=O)C12CC3CC(CC(C3)(C1)NC(=O)[C@@]1(C)CCC[C@@]3(C)[C@H]1CCc1ccc(O)cc31)C2 InChI=1S/C30H41NO4/c1-4-35-26(34)29-14-19-12-20(15-29)17-30(16-19,18-29)31-25(33)28(3)11-5-10-27(2)23-13-22(32)8-6-21(23)7-9-24(27)28/h6,8,13,19-20,24,32H,4-5,7,9-12,14-18H2,1-3H3,(H,31,33)/t19?,20?,24-,27-,28+,29?,30?/m1/s1 DYTISOKVYHWYCW-ZOQHKRPUSA-N 50172191 3-[((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amino]-adamantane-1-carboxylic acid ethyl ester::CHEMBL196335 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172191&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403655 104058320 CHEMBL196335 ZINC28524404 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131062 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC1CC2CCC1C2 InChI=1S/C24H33NO2/c1-23-10-3-11-24(2,22(27)25-20-13-15-4-5-17(20)12-15)21(23)9-7-16-6-8-18(26)14-19(16)23/h6,8,14-15,17,20-21,26H,3-5,7,9-13H2,1-2H3,(H,25,27)/t15?,17?,20?,21-,23-,24+/m1/s1 QFGBXMNKPLHDLK-SMPAFLLBSA-N 50172202 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid bicyclo[2.2.1]hept-2-ylamide::CHEMBL424831 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172202&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403633 104058331 CHEMBL424831 ZINC28526437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131063 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NCC12CC3CC(CC(C3)C1)C2 InChI=1S/C28H39NO2/c1-26-8-3-9-27(2,24(26)7-5-21-4-6-22(30)13-23(21)26)25(31)29-17-28-14-18-10-19(15-28)12-20(11-18)16-28/h4,6,13,18-20,24,30H,3,5,7-12,14-17H2,1-2H3,(H,29,31)/t18?,19?,20?,24-,26-,27+,28?/m1/s1 DHBIWVAWNUNKJG-WPKHNGPTSA-N 50172185 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (adamantan-1-ylmethyl)-amide::(4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (adamantan-1-ylmethyl)-amide::CHEMBL194642 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172185&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10070833 104058314 CHEMBL194642 ZINC28526438 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131065 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)N1C2CCCCC2C2CCCCC12 InChI=1S/C29H41NO2/c1-28-16-7-17-29(2,26(28)15-13-19-12-14-20(31)18-23(19)28)27(32)30-24-10-5-3-8-21(24)22-9-4-6-11-25(22)30/h12,14,18,21-22,24-26,31H,3-11,13,15-17H2,1-2H3/t21?,22?,24?,25?,26-,28-,29+/m1/s1 QBUILYGRQMFSAV-MCUVCGQJSA-N 50172192 (Dodecahydro-carbazol-9-yl)-((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-methanone::CHEMBL370175 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172192&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403656 104058321 CHEMBL370175 ZINC38153854 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131067 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCC2(CC1)C=Cc1ccccc21 InChI=1S/C30H35NO/c1-28-15-7-16-29(2,26(28)13-12-22-8-3-5-10-24(22)28)27(32)31-20-18-30(19-21-31)17-14-23-9-4-6-11-25(23)30/h3-6,8-11,14,17,26H,7,12-13,15-16,18-21H2,1-2H3/t26-,28-,29+/m1/s1 YOBSSBAJFVWQAA-CMYDWJSCSA-N 50172198 2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-trien-6-yl-spiro[1H-indene-1,4'-(hexahydropyridine)]-1-ylmethanone::CHEMBL197265 Oxysterols receptor LXR-beta 1500 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172198&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403564 104058327 CHEMBL197265 ZINC28525355 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131068 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCCC(C1)c1ccccc1 InChI=1S/C28H35NO/c1-27-17-9-18-28(2,25(27)16-15-22-12-6-7-14-24(22)27)26(30)29-19-8-13-23(20-29)21-10-4-3-5-11-21/h3-7,10-12,14,23,25H,8-9,13,15-20H2,1-2H3/t23?,25-,27-,28+/m1/s1 KCTVTEAWWHOHNZ-MYKDWEDJSA-N 50172189 ((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-(3-phenyl-piperidin-1-yl)-methanone::CHEMBL196340 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172189&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403565 104058318 CHEMBL196340 ZINC28525357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131069 CC(CNC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccccc21)(c1ccccc1)c1ccccc1 InChI=1S/C32H37NO/c1-30-21-12-22-31(2,28(30)20-19-24-13-10-11-18-27(24)30)29(34)33-23-32(3,25-14-6-4-7-15-25)26-16-8-5-9-17-26/h4-11,13-18,28H,12,19-23H2,1-3H3,(H,33,34)/t28-,30-,31+/m1/s1 FCQLLWXAPLXYQV-HQMADOEBSA-N 50172203 (1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (2,2-diphenyl-propyl)-amide::CHEMBL365750 Oxysterols receptor LXR-beta 420 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172203&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403557 104058332 CHEMBL365750 ZINC28526141 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131070 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCC(CC1)c1ccccc1 InChI=1S/C28H35NO/c1-27-17-8-18-28(2,25(27)14-13-23-11-6-7-12-24(23)27)26(30)29-19-15-22(16-20-29)21-9-4-3-5-10-21/h3-7,9-12,22,25H,8,13-20H2,1-2H3/t25-,27-,28+/m1/s1 ZJPIFOVRFHBVNC-KZQOYIJHSA-N 50172195 ((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-(4-phenyl-piperidin-1-yl)-methanone::CHEMBL194733 Oxysterols receptor LXR-beta 180 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172195&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403558 104058324 CHEMBL194733 ZINC28526142 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131073 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC1C2CC3CC(C2)CC1C3 InChI=1S/C27H37NO2/c1-26-8-3-9-27(2,23(26)7-5-18-4-6-21(29)15-22(18)26)25(30)28-24-19-11-16-10-17(13-19)14-20(24)12-16/h4,6,15-17,19-20,23-24,29H,3,5,7-14H2,1-2H3,(H,28,30)/t16?,17?,19?,20?,23-,24?,26-,27+/m1/s1 GBNHOQWDXVLAFY-SRYDNDORSA-N 50172188 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid adamantan-2-ylamide::CHEMBL194409 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172188&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10001458 104058317 CHEMBL194409 ZINC28526481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131074 CC(=O)Oc1ccc2CC[C@H]3C(C)(CCC[C@]3(C)c2c1)C(=O)OC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(OC(C)=O)cc21 InChI=1S/C38H46O7/c1-23(39)43-27-13-9-25-11-15-31-35(3,29(25)21-27)17-7-19-37(31,5)33(41)45-34(42)38(6)20-8-18-36(4)30-22-28(44-24(2)40)14-10-26(30)12-16-32(36)38/h9-10,13-14,21-22,31-32H,7-8,11-12,15-20H2,1-6H3/t31-,32-,35-,36-,37+,38?/m1/s1 OUJQRQRBNRGQTC-PWAHEJKMSA-N 50167694 2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-triene-6-carboxylic anhydride::2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL191965 Oxysterols receptor LXR-beta 10 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400646 104052910 CHEMBL191965 ZINC38149326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131076 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCCC=C InChI=1S/C21H28O3/c1-4-5-13-24-19(23)21(3)12-6-11-20(2)17-14-16(22)9-7-15(17)8-10-18(20)21/h4,7,9,14,18,22H,1,5-6,8,10-13H2,2-3H3/t18-,20-,21+/m1/s1 DIWGSLNGJZKMCD-NRSPTQNISA-N 50172194 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid but-3-enyl ester::CHEMBL194192 Oxysterols receptor LXR-beta 3850 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172194&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403620 104058323 CHEMBL194192 ZINC28526611 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131077 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCCCC=C InChI=1S/C22H30O3/c1-4-5-6-14-25-20(24)22(3)13-7-12-21(2)18-15-17(23)10-8-16(18)9-11-19(21)22/h4,8,10,15,19,23H,1,5-7,9,11-14H2,2-3H3/t19-,21-,22+/m1/s1 OGWPEHWENJNJMA-FCEUIQTBSA-N 50172205 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid pent-4-enyl ester::CHEMBL426289 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172205&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403625 104058334 CHEMBL426289 ZINC28524508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131078 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NCCc1ccccc1 InChI=1S/C25H31NO2/c1-24-14-6-15-25(2,23(28)26-16-13-18-7-4-3-5-8-18)22(24)12-10-19-9-11-20(27)17-21(19)24/h3-5,7-9,11,17,22,27H,6,10,12-16H2,1-2H3,(H,26,28)/t22-,24-,25+/m1/s1 DYNZVVWJZHKCKP-GPXOXTDOSA-N 50172193 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid phenethyl-amide::CHEMBL196145 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172193&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403626 104058322 CHEMBL196145 ZINC28524510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131079 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)OCCCC=C InChI=1S/C22H30O3/c1-4-5-6-14-25-20(24)22(3)13-7-12-21(2)18-15-17(23)10-8-16(18)9-11-19(21)22/h4,8,10,15,19,23H,1,5-7,9,11-14H2,2-3H3/t19-,21-,22+/m1/s1 OGWPEHWENJNJMA-FCEUIQTBSA-N 50172205 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid pent-4-enyl ester::CHEMBL426289 Oxysterols receptor LXR-beta 5000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172205&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403625 104058334 CHEMBL426289 ZINC28524508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131080 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NCCc1ccccc1 InChI=1S/C25H31NO2/c1-24-14-6-15-25(2,23(28)26-16-13-18-7-4-3-5-8-18)22(24)12-10-19-9-11-20(27)17-21(19)24/h3-5,7-9,11,17,22,27H,6,10,12-16H2,1-2H3,(H,26,28)/t22-,24-,25+/m1/s1 DYNZVVWJZHKCKP-GPXOXTDOSA-N 50172193 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid phenethyl-amide::CHEMBL196145 Oxysterols receptor LXR-beta 2220 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172193&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403626 104058322 CHEMBL196145 ZINC28524510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131085 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NC(=O)C1(CCCCC1)c1ccccc1 InChI=1S/C30H37NO2/c1-28-18-11-19-29(2,25(28)17-16-22-12-7-8-15-24(22)28)26(32)31-27(33)30(20-9-4-10-21-30)23-13-5-3-6-14-23/h3,5-8,12-15,25H,4,9-11,16-21H2,1-2H3,(H,31,32,33)/t25-,28-,29+/m1/s1 RFGMOPNIYZVCFS-ZJGIAAPESA-N 50172199 1-Phenyl-cyclohexanecarboxylic acid ((1S,4aS,10aR)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL194573 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172199&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403571 104058328 CHEMBL194573 ZINC28525805 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131092 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H43NO4/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(36)19-25(21)31)29(38)35-30(39)34(4)18-6-16-32(2)26-20-24(37)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,36-37H,5-6,9-10,13-18H2,1-4H3,(H,35,38,39)/t27-,28-,31-,32-,33+,34?/m1/s1 ASTLYMNMTDERKI-IMUKZWIGSA-N 50167697 (4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::(4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL365544 Oxysterols receptor LXR-beta 1 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400748 104052913 CHEMBL365544 ZINC28520935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131094 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NC(=O)C12CC3CC(CC(C3)C1)C2 InChI=1S/C28H37NO2/c1-26-10-5-11-27(2,23(26)9-8-21-6-3-4-7-22(21)26)24(30)29-25(31)28-15-18-12-19(16-28)14-20(13-18)17-28/h3-4,6-7,18-20,23H,5,8-17H2,1-2H3,(H,29,30,31)/t18?,19?,20?,23-,26-,27+,28?/m1/s1 IEPOYBLCAUUPJP-GDCRIOODSA-N 50172207 Adamantane-1-carboxylic acid ((1S,4aS,10aR)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL194679 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172207&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403570 104058336 CHEMBL194679 ZINC28526118 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131102 CC1(C)C2CC1C(CC2)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C26H37NO2/c1-24(2)17-8-10-21(20(24)14-17)27-23(29)26(4)13-5-12-25(3)19-15-18(28)9-6-16(19)7-11-22(25)26/h6,9,15,17,20-22,28H,5,7-8,10-14H2,1-4H3,(H,27,29)/t17?,20?,21?,22-,25-,26+/m1/s1 GREUENDQALGMMV-XSYRNFCJSA-N 50172197 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (6,6-dimethyl-bicyclo[3.1.1]hept-2-yl)-amide::CHEMBL197522 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172197&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403639 104058326 CHEMBL197522 ZINC28525864 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131122 CC(NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C12CC3CC(CC(C3)C1)C2 InChI=1S/C29H41NO2/c1-18(29-15-19-11-20(16-29)13-21(12-19)17-29)30-26(32)28(3)10-4-9-27(2)24-14-23(31)7-5-22(24)6-8-25(27)28/h5,7,14,18-21,25,31H,4,6,8-13,15-17H2,1-3H3,(H,30,32)/t18?,19?,20?,21?,25-,27-,28+,29?/m1/s1 AEORYXMWRGDQDS-LIFQUHLFSA-N 50172206 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (1-adamantan-1-yl-ethyl)-amide::CHEMBL371990 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172206&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10252443 104058335 CHEMBL371990 ZINC28525862 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131138 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCC2(CC1)C=Cc1ccccc21 InChI=1S/C30H35NO/c1-28-15-7-16-29(2,26(28)13-12-22-8-3-5-10-24(22)28)27(32)31-20-18-30(19-21-31)17-14-23-9-4-6-11-25(23)30/h3-6,8-11,14,17,26H,7,12-13,15-16,18-21H2,1-2H3/t26-,28-,29+/m1/s1 YOBSSBAJFVWQAA-CMYDWJSCSA-N 50172198 2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-trien-6-yl-spiro[1H-indene-1,4'-(hexahydropyridine)]-1-ylmethanone::CHEMBL197265 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172198&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403564 104058327 CHEMBL197265 ZINC28525355 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131139 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)N1CCCC(C1)c1ccccc1 InChI=1S/C28H35NO/c1-27-17-9-18-28(2,25(27)16-15-22-12-6-7-14-24(22)27)26(30)29-19-8-13-23(20-29)21-10-4-3-5-11-21/h3-7,10-12,14,23,25H,8-9,13,15-20H2,1-2H3/t23?,25-,27-,28+/m1/s1 KCTVTEAWWHOHNZ-MYKDWEDJSA-N 50172189 ((1S,4aS,10aR)-1,4a-Dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-(3-phenyl-piperidin-1-yl)-methanone::CHEMBL196340 Oxysterols receptor LXR-beta 370 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172189&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403565 104058318 CHEMBL196340 ZINC28525357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131143 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H43NO4/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(36)19-25(21)31)29(38)35-30(39)34(4)18-6-16-32(2)26-20-24(37)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,36-37H,5-6,9-10,13-18H2,1-4H3,(H,35,38,39)/t27-,28-,31-,32-,33+,34?/m1/s1 ASTLYMNMTDERKI-IMUKZWIGSA-N 50167697 (4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::(4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL365544 Oxysterols receptor LXR-beta <3 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400748 104052913 CHEMBL365544 ZINC28520935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131150 CCOC(=O)C12CC3CC(CC(C3)(C1)NC(=O)[C@@]1(C)CCC[C@@]3(C)[C@H]1CCc1ccc(O)cc31)C2 InChI=1S/C30H41NO4/c1-4-35-26(34)29-14-19-12-20(15-29)17-30(16-19,18-29)31-25(33)28(3)11-5-10-27(2)23-13-22(32)8-6-21(23)7-9-24(27)28/h6,8,13,19-20,24,32H,4-5,7,9-12,14-18H2,1-3H3,(H,31,33)/t19?,20?,24-,27-,28+,29?,30?/m1/s1 DYTISOKVYHWYCW-ZOQHKRPUSA-N 50172191 3-[((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amino]-adamantane-1-carboxylic acid ethyl ester::CHEMBL196335 Oxysterols receptor LXR-beta 530 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172191&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403655 104058320 CHEMBL196335 ZINC28524404 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131151 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC1CC2CCC1C2 InChI=1S/C24H33NO2/c1-23-10-3-11-24(2,22(27)25-20-13-15-4-5-17(20)12-15)21(23)9-7-16-6-8-18(26)14-19(16)23/h6,8,14-15,17,20-21,26H,3-5,7,9-13H2,1-2H3,(H,25,27)/t15?,17?,20?,21-,23-,24+/m1/s1 QFGBXMNKPLHDLK-SMPAFLLBSA-N 50172202 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid bicyclo[2.2.1]hept-2-ylamide::CHEMBL424831 Oxysterols receptor LXR-beta 4120 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172202&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403633 104058331 CHEMBL424831 ZINC28526437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131154 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)N1C2CCCCC2C2CCCCC12 InChI=1S/C29H41NO2/c1-28-16-7-17-29(2,26(28)15-13-19-12-14-20(31)18-23(19)28)27(32)30-24-10-5-3-8-21(24)22-9-4-6-11-25(22)30/h12,14,18,21-22,24-26,31H,3-11,13,15-17H2,1-2H3/t21?,22?,24?,25?,26-,28-,29+/m1/s1 QBUILYGRQMFSAV-MCUVCGQJSA-N 50172192 (Dodecahydro-carbazol-9-yl)-((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-methanone::CHEMBL370175 Oxysterols receptor LXR-beta 190 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172192&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44403656 104058321 CHEMBL370175 ZINC38153854 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131162 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NCC12CC3CC(CC(C3)C1)C2 InChI=1S/C28H39NO2/c1-26-8-3-9-27(2,24(26)7-5-21-4-6-22(30)13-23(21)26)25(31)29-17-28-14-18-10-19(15-28)12-20(11-18)16-28/h4,6,13,18-20,24,30H,3,5,7-12,14-17H2,1-2H3,(H,29,31)/t18?,19?,20?,24-,26-,27+,28?/m1/s1 DHBIWVAWNUNKJG-WPKHNGPTSA-N 50172185 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (adamantan-1-ylmethyl)-amide::(4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (adamantan-1-ylmethyl)-amide::CHEMBL194642 Oxysterols receptor LXR-beta 190 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172185&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10070833 104058314 CHEMBL194642 ZINC28526438 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50131167 CC(=O)Oc1ccc2CC[C@H]3C(C)(CCC[C@]3(C)c2c1)C(=O)OC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(OC(C)=O)cc21 InChI=1S/C38H46O7/c1-23(39)43-27-13-9-25-11-15-31-35(3,29(25)21-27)17-7-19-37(31,5)33(41)45-34(42)38(6)20-8-18-36(4)30-22-28(44-24(2)40)14-10-26(30)12-16-32(36)38/h9-10,13-14,21-22,31-32H,7-8,11-12,15-20H2,1-6H3/t31-,32-,35-,36-,37+,38?/m1/s1 OUJQRQRBNRGQTC-PWAHEJKMSA-N 50167694 2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-triene-6-carboxylic anhydride::2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL191965 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2005.06.100 10.7270/Q2154GKK 16125384 Liu, W; Chen, S; Dropinski, J; Colwell, L; Robins, M; Szymonifka, M; Hayes, N; Sharma, N; MacNaul, K; Hernandez, M; Burton, C; Sparrow, CP; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400646 104052910 CHEMBL191965 ZINC38149326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135421 CCCc1c(OCCCn2ncc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C23H22F3N3O4/c1-2-4-16-19(8-6-17-21(16)33-28-22(17)23(24,25)26)32-10-3-9-29-18-7-5-14(12-20(30)31)11-15(18)13-27-29/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,30,31) ZFCIXIWMXLHUDY-UHFFFAOYSA-N 50184248 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indazol-5-yl)acetic acid::CHEMBL210917 Oxysterols receptor LXR-beta 580 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184248&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11626766 104068642 CHEMBL210917 ZINC35952520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135422 CCCc1c(OCCCN(C)c2cnc(CC(O)=O)cn2)ccc2c(noc12)C(F)(F)F InChI=1S/C21H23F3N4O4/c1-3-5-14-16(7-6-15-19(14)32-27-20(15)21(22,23)24)31-9-4-8-28(2)17-12-25-13(11-26-17)10-18(29)30/h6-7,11-12H,3-5,8-10H2,1-2H3,(H,29,30) YOZGUTZZNGXRCT-UHFFFAOYSA-N 50184273 2-(5-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)pyrazin-2-yl)acetic acid::CHEMBL378074 Oxysterols receptor LXR-beta 150 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184273&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11503359 104068667 CHEMBL378074 ZINC38157660 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135423 CCCc1c(OCCCn2ncc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C23H22F3N3O4/c1-2-4-16-19(8-6-17-21(16)33-28-22(17)23(24,25)26)32-10-3-9-29-18-7-5-14(12-20(30)31)11-15(18)13-27-29/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,30,31) ZFCIXIWMXLHUDY-UHFFFAOYSA-N 50184248 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indazol-5-yl)acetic acid::CHEMBL210917 Oxysterols receptor LXR-beta 87 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184248&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11626766 104068642 CHEMBL210917 ZINC35952520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135424 CCCc1c(OCCCOc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO5/c1-2-4-14-17(8-6-15-20(14)32-27-21(15)22(24,25)26)30-9-3-10-31-18-7-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) FAYRZYDHLUVKKC-UHFFFAOYSA-N 50184263 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propoxy)phenyl)acetic acid::CHEMBL210768 Oxysterols receptor LXR-beta 9700 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184263&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411653 104068657 CHEMBL210768 ZINC34717667 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135425 CCCc1c(OCCCOc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO5/c1-2-4-14-17(8-6-15-20(14)32-27-21(15)22(24,25)26)30-9-3-10-31-18-7-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) FAYRZYDHLUVKKC-UHFFFAOYSA-N 50184263 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propoxy)phenyl)acetic acid::CHEMBL210768 Oxysterols receptor LXR-beta 65 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184263&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411653 104068657 CHEMBL210768 ZINC34717667 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135426 CCCc1c(OCCCN(C)c2ncc(CC(O)=O)cn2)ccc2c(noc12)C(F)(F)F InChI=1S/C21H23F3N4O4/c1-3-5-14-16(7-6-15-18(14)32-27-19(15)21(22,23)24)31-9-4-8-28(2)20-25-11-13(12-26-20)10-17(29)30/h6-7,11-12H,3-5,8-10H2,1-2H3,(H,29,30) HNBMEVGNLQVKHO-UHFFFAOYSA-N 50184270 2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)pyrimidin-5-yl)acetic acid::CHEMBL210990 Oxysterols receptor LXR-beta 55 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184270&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11576047 104068664 CHEMBL210990 ZINC35850008 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135427 CCCc1c(OCCCN(C)c2cnc(CC(O)=O)cn2)ccc2c(noc12)C(F)(F)F InChI=1S/C21H23F3N4O4/c1-3-5-14-16(7-6-15-19(14)32-27-20(15)21(22,23)24)31-9-4-8-28(2)17-12-25-13(11-26-17)10-18(29)30/h6-7,11-12H,3-5,8-10H2,1-2H3,(H,29,30) YOZGUTZZNGXRCT-UHFFFAOYSA-N 50184273 2-(5-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)pyrazin-2-yl)acetic acid::CHEMBL378074 Oxysterols receptor LXR-beta 40 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184273&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11503359 104068667 CHEMBL378074 ZINC38157660 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135428 CCCc1c(OCCCN(C)c2ncc(CC(O)=O)cn2)ccc2c(noc12)C(F)(F)F InChI=1S/C21H23F3N4O4/c1-3-5-14-16(7-6-15-18(14)32-27-19(15)21(22,23)24)31-9-4-8-28(2)20-25-11-13(12-26-20)10-17(29)30/h6-7,11-12H,3-5,8-10H2,1-2H3,(H,29,30) HNBMEVGNLQVKHO-UHFFFAOYSA-N 50184270 2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)pyrimidin-5-yl)acetic acid::CHEMBL210990 Oxysterols receptor LXR-beta 470 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184270&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11576047 104068664 CHEMBL210990 ZINC35850008 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135429 CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO4S/c1-2-4-14-17(7-6-15-20(14)31-27-21(15)22(24,25)26)30-9-3-10-32-18-8-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) TZBRFAASYWFUGK-UHFFFAOYSA-N 50126018 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid::CHEMBL23296::{3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid::{3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)sulfanyl]phenyl}acetic acid Oxysterols receptor LXR-beta 7300 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O90 3IPS 9935197 104018161 CHEMBL23296 2688 ZINC03834054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135430 CCCc1c(OCCCN(C)c2ccccc2)ccc2c(noc12)C(F)(F)F InChI=1S/C21H23F3N2O2/c1-3-8-16-18(12-11-17-19(16)28-25-20(17)21(22,23)24)27-14-7-13-26(2)15-9-5-4-6-10-15/h4-6,9-12H,3,7-8,13-14H2,1-2H3 FFEMTQPBRTULCE-UHFFFAOYSA-N 50184269 CHEMBL207236::N-methyl-N-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)benzenamine Oxysterols receptor LXR-beta 428 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184269&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411622 104068663 CHEMBL207236 ZINC38157666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135432 CCCc1c(OCCCNc2ccc(CC(O)=O)cc2)ccc2c(noc12)C(F)(F)F InChI=1S/C22H23F3N2O4/c1-2-4-16-18(10-9-17-20(16)31-27-21(17)22(23,24)25)30-12-3-11-26-15-7-5-14(6-8-15)13-19(28)29/h5-10,26H,2-4,11-13H2,1H3,(H,28,29) SUSIJEPKDLCOFC-UHFFFAOYSA-N 50184274 2-(4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylamino)phenyl)acetic acid::CHEMBL207103 Oxysterols receptor LXR-beta 7700 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184274&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411843 104068668 CHEMBL207103 C03768 ZINC34717664 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135433 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)cc2)ccc2c(noc12)C(F)(F)F InChI=1S/C23H25F3N2O4/c1-3-5-17-19(11-10-18-21(17)32-27-22(18)23(24,25)26)31-13-4-12-28(2)16-8-6-15(7-9-16)14-20(29)30/h6-11H,3-5,12-14H2,1-2H3,(H,29,30) FAQHMFAPRWBDDB-UHFFFAOYSA-N 50184254 2-(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL207019 Oxysterols receptor LXR-beta 360 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184254&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411842 104068648 CHEMBL207019 C03768 ZINC34717660 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135435 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)c(Cl)c2)ccc2c(noc12)C(F)(F)F InChI=1S/C23H24ClF3N2O4/c1-3-5-16-19(9-8-17-21(16)33-28-22(17)23(25,26)27)32-11-4-10-29(2)15-7-6-14(12-20(30)31)18(24)13-15/h6-9,13H,3-5,10-12H2,1-2H3,(H,30,31) JRJIJEXVKDFRTL-UHFFFAOYSA-N 50184259 2-(2-chloro-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL208967 Oxysterols receptor LXR-beta 10 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184259&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44412005 104068653 CHEMBL208967 ZINC37866921 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135436 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)c(C)c2)ccc2c(noc12)C(F)(F)F InChI=1S/C24H27F3N2O4/c1-4-6-18-20(10-9-19-22(18)33-28-23(19)24(25,26)27)32-12-5-11-29(3)17-8-7-16(14-21(30)31)15(2)13-17/h7-10,13H,4-6,11-12,14H2,1-3H3,(H,30,31) AVSJVGZIDNEDSK-UHFFFAOYSA-N 50184256 2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL427040 Oxysterols receptor LXR-beta 303 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184256&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44412195 104068650 CHEMBL427040 ZINC34717665 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135437 CCCc1c(OCCCN(C)c2ncc(CC(O)=O)s2)ccc2c(noc12)C(F)(F)F InChI=1S/C20H22F3N3O4S/c1-3-5-13-15(7-6-14-17(13)30-25-18(14)20(21,22)23)29-9-4-8-26(2)19-24-11-12(31-19)10-16(27)28/h6-7,11H,3-5,8-10H2,1-2H3,(H,27,28) OVJGYBFXJVQSHK-UHFFFAOYSA-N 50184264 2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)thiazol-5-yl)acetic acid::CHEMBL381064 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184264&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11525365 104068658 CHEMBL381064 ZINC38157661 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135438 CCCc1c(OCCCN2C(=O)Cc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C24H23F3N2O5/c1-2-4-16-19(8-6-17-22(16)34-28-23(17)24(25,26)27)33-10-3-9-29-18-7-5-14(12-21(31)32)11-15(18)13-20(29)30/h5-8,11H,2-4,9-10,12-13H2,1H3,(H,31,32) WRGYDZSMTYBYJC-UHFFFAOYSA-N 50184257 2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)indolin-5-yl)acetic acid::CHEMBL207690 Oxysterols receptor LXR-beta 13 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184257&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11583743 104068651 CHEMBL207690 ZINC35863073 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135439 CCCc1c(OCCCn2ccc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C24H23F3N2O4/c1-2-4-17-20(8-6-18-22(17)33-28-23(18)24(25,26)27)32-12-3-10-29-11-9-16-13-15(14-21(30)31)5-7-19(16)29/h5-9,11,13H,2-4,10,12,14H2,1H3,(H,30,31) VPVFJCQJGDFRIA-UHFFFAOYSA-N 50184255 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indol-5-yl)acetic acid::CHEMBL383728 Oxysterols receptor LXR-beta 16 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184255&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11669781 104068649 CHEMBL383728 ZINC34717663 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135441 CCCc1c(OCCCN(C)c2ccc(cc2)C(O)=O)ccc2c(noc12)C(F)(F)F InChI=1S/C22H23F3N2O4/c1-3-5-16-18(11-10-17-19(16)31-26-20(17)22(23,24)25)30-13-4-12-27(2)15-8-6-14(7-9-15)21(28)29/h6-11H,3-5,12-13H2,1-2H3,(H,28,29) PNGBFYGVOOVAIY-UHFFFAOYSA-N 50184251 4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)benzoic acid::CHEMBL207142 Oxysterols receptor LXR-beta 190 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184251&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11697813 104068645 CHEMBL207142 ZINC38157665 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135448 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)c(c2)C(F)(F)F)ccc2c(noc12)C(F)(F)F InChI=1S/C24H24F6N2O4/c1-3-5-16-19(9-8-17-21(16)36-31-22(17)24(28,29)30)35-11-4-10-32(2)15-7-6-14(12-20(33)34)18(13-15)23(25,26)27/h6-9,13H,3-5,10-12H2,1-2H3,(H,33,34) XNZXFVFJRAJUDY-UHFFFAOYSA-N 50184250 2-(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)-2-(trifluoromethyl)phenyl)acetic acid::CHEMBL382789 Oxysterols receptor LXR-beta 18 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184250&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44412006 104068644 CHEMBL382789 ZINC37866920 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135457 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)cn2)ccc2c(noc12)C(F)(F)F InChI=1S/C22H24F3N3O4/c1-3-5-15-17(8-7-16-20(15)32-27-21(16)22(23,24)25)31-11-4-10-28(2)18-9-6-14(13-26-18)12-19(29)30/h6-9,13H,3-5,10-12H2,1-2H3,(H,29,30) KXKUFEBWUQXFEK-UHFFFAOYSA-N 50184252 2-(6-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)pyridin-3-yl)acetic acid::CHEMBL207188 Oxysterols receptor LXR-beta 630 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184252&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11619338 104068646 CHEMBL207188 ZINC38157662 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135463 CCCc1c(OCCCn2cnc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C23H22F3N3O4/c1-2-4-15-19(8-6-16-21(15)33-28-22(16)23(24,25)26)32-10-3-9-29-13-27-17-11-14(12-20(30)31)5-7-18(17)29/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,30,31) GMKDRYOJWQXLTE-UHFFFAOYSA-N 50184275 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-benzo[d]imidazol-5-yl)acetic acid::CHEMBL210613 Oxysterols receptor LXR-beta 8600 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184275&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11655554 104068669 CHEMBL210613 ZINC37866923 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135466 CCCc1c(OCCCN2C(=O)Cc3cc(ccc23)C(O)=O)ccc2c(noc12)C(F)(F)F InChI=1S/C23H21F3N2O5/c1-2-4-15-18(8-6-16-20(15)33-27-21(16)23(24,25)26)32-10-3-9-28-17-7-5-13(22(30)31)11-14(17)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,30,31) JBHHUSIDAMWIJB-UHFFFAOYSA-N 50184262 2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)indoline-5-carboxylic acid::CHEMBL207382 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184262&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11655575 104068656 CHEMBL207382 ZINC38157664 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135470 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)cc2C)ccc2c(noc12)C(F)(F)F InChI=1S/C24H27F3N2O4/c1-4-6-17-20(10-8-18-22(17)33-28-23(18)24(25,26)27)32-12-5-11-29(3)19-9-7-16(13-15(19)2)14-21(30)31/h7-10,13H,4-6,11-12,14H2,1-3H3,(H,30,31) GZAPSISRDWGGFB-UHFFFAOYSA-N 50184258 2-(3-methyl-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL209563 Oxysterols receptor LXR-beta 320 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184258&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44412188 104068652 CHEMBL209563 ZINC34717668 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135471 CCCc1c(OCCCN(C)c2cccc(CC(O)=O)c2)ccc2c(noc12)C(F)(F)F InChI=1S/C23H25F3N2O4/c1-3-6-17-19(10-9-18-21(17)32-27-22(18)23(24,25)26)31-12-5-11-28(2)16-8-4-7-15(13-16)14-20(29)30/h4,7-10,13H,3,5-6,11-12,14H2,1-2H3,(H,29,30) KNURBYIANGVDEG-UHFFFAOYSA-N 50184253 2-(3-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL207442 Oxysterols receptor LXR-beta 3500 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184253&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411977 104068647 CHEMBL207442 ZINC34717661 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135475 CCCc1c(OCCCN(C)c2cccc(CC(O)=O)c2)ccc2c(noc12)C(F)(F)F InChI=1S/C23H25F3N2O4/c1-3-6-17-19(10-9-18-21(17)32-27-22(18)23(24,25)26)31-12-5-11-28(2)16-8-4-7-15(13-16)14-20(29)30/h4,7-10,13H,3,5-6,11-12,14H2,1-2H3,(H,29,30) KNURBYIANGVDEG-UHFFFAOYSA-N 50184253 2-(3-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL207442 Oxysterols receptor LXR-beta 98 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184253&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411977 104068647 CHEMBL207442 ZINC34717661 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135482 CCCc1c(OCCCn2ccc3cc(ccc23)C(O)=O)ccc2c(noc12)C(F)(F)F InChI=1S/C23H21F3N2O4/c1-2-4-16-19(8-6-17-20(16)32-27-21(17)23(24,25)26)31-12-3-10-28-11-9-14-13-15(22(29)30)5-7-18(14)28/h5-9,11,13H,2-4,10,12H2,1H3,(H,29,30) WJPMVXGXXLNBEN-UHFFFAOYSA-N 50184268 1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indole-5-carboxylic acid::CHEMBL377218 Oxysterols receptor LXR-beta 199 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184268&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11704978 104068662 CHEMBL377218 ZINC38157663 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135483 CCCc1c(OCCCn2ccc3cc(CCC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C25H25F3N2O4/c1-2-4-18-21(9-7-19-23(18)34-29-24(19)25(26,27)28)33-14-3-12-30-13-11-17-15-16(5-8-20(17)30)6-10-22(31)32/h5,7-9,11,13,15H,2-4,6,10,12,14H2,1H3,(H,31,32) AORBCLGGYNFMGN-UHFFFAOYSA-N 50184249 3-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indol-5-yl)propanoic acid::CHEMBL207907 Oxysterols receptor LXR-beta 6 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184249&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11525752 104068643 CHEMBL207907 ZINC34717662 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135484 CCCc1c(OCCCCc2ccc(CC(O)=O)cc2)ccc2c(noc12)C(F)(F)F InChI=1S/C23H24F3NO4/c1-2-5-17-19(12-11-18-21(17)31-27-22(18)23(24,25)26)30-13-4-3-6-15-7-9-16(10-8-15)14-20(28)29/h7-12H,2-6,13-14H2,1H3,(H,28,29) VRCMDLDBHFNHBT-UHFFFAOYSA-N 50184271 2-(4-(4-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)butyl)phenyl)acetic acid::CHEMBL210454 Oxysterols receptor LXR-beta 970 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184271&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411810 104068665 CHEMBL210454 C03768 ZINC38157669 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135485 CCCc1c(OCCCn2ccc3cc(ccc23)C(O)=O)ccc2c(noc12)C(F)(F)F InChI=1S/C23H21F3N2O4/c1-2-4-16-19(8-6-17-20(16)32-27-21(17)23(24,25)26)31-12-3-10-28-11-9-14-13-15(22(29)30)5-7-18(14)28/h5-9,11,13H,2-4,10,12H2,1H3,(H,29,30) WJPMVXGXXLNBEN-UHFFFAOYSA-N 50184268 1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indole-5-carboxylic acid::CHEMBL377218 Oxysterols receptor LXR-beta 2800 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184268&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11704978 104068662 CHEMBL377218 ZINC38157663 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135486 CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO4S/c1-2-4-14-17(7-6-15-20(14)31-27-21(15)22(24,25)26)30-9-3-10-32-18-8-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) TZBRFAASYWFUGK-UHFFFAOYSA-N 50126018 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid::CHEMBL23296::{3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid::{3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)sulfanyl]phenyl}acetic acid Oxysterols receptor LXR-beta 28 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O90 3IPS 9935197 104018161 CHEMBL23296 2688 ZINC03834054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135487 CCCc1c(OCCCn2ccc3cc(CCC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C25H25F3N2O4/c1-2-4-18-21(9-7-19-23(18)34-29-24(19)25(26,27)28)33-14-3-12-30-13-11-17-15-16(5-8-20(17)30)6-10-22(31)32/h5,7-9,11,13,15H,2-4,6,10,12,14H2,1H3,(H,31,32) AORBCLGGYNFMGN-UHFFFAOYSA-N 50184249 3-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indol-5-yl)propanoic acid::CHEMBL207907 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184249&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11525752 104068643 CHEMBL207907 ZINC34717662 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135492 CCCc1c(OCCCn2nnc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21F3N4O4/c1-2-4-14-18(8-6-15-20(14)33-27-21(15)22(23,24)25)32-10-3-9-29-17-7-5-13(12-19(30)31)11-16(17)26-28-29/h5-8,11H,2-4,9-10,12H2,1H3,(H,30,31) CQTCWVWUQDCTSG-UHFFFAOYSA-N 50184272 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-benzo[d][1,2,3]triazol-5-yl)acetic acid::CHEMBL208567 Oxysterols receptor LXR-beta 350 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184272&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11705301 104068666 CHEMBL208567 ZINC37866922 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135497 CCCc1c(OCCCn2nnc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21F3N4O4/c1-2-4-14-18(8-6-15-20(14)33-27-21(15)22(23,24)25)32-10-3-9-29-17-7-5-13(12-19(30)31)11-16(17)26-28-29/h5-8,11H,2-4,9-10,12H2,1H3,(H,30,31) CQTCWVWUQDCTSG-UHFFFAOYSA-N 50184272 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-benzo[d][1,2,3]triazol-5-yl)acetic acid::CHEMBL208567 Oxysterols receptor LXR-beta 1700 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184272&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11705301 104068666 CHEMBL208567 ZINC37866922 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135498 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C23H24ClF3N2O4/c1-3-5-15-19(9-7-16-21(15)33-28-22(16)23(25,26)27)32-11-4-10-29(2)18-8-6-14(12-17(18)24)13-20(30)31/h6-9,12H,3-5,10-11,13H2,1-2H3,(H,30,31) GADXIGHAARSCIO-UHFFFAOYSA-N 50184260 2-(3-chloro-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL383646 Oxysterols receptor LXR-beta 170 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184260&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411838 104068654 CHEMBL383646 ZINC37866925 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135499 CCCc1c(OCCCN2C(=O)Cc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C24H23F3N2O5/c1-2-4-16-19(8-6-17-22(16)34-28-23(17)24(25,26)27)33-10-3-9-29-18-7-5-14(12-21(31)32)11-15(18)13-20(29)30/h5-8,11H,2-4,9-10,12-13H2,1H3,(H,31,32) WRGYDZSMTYBYJC-UHFFFAOYSA-N 50184257 2-(2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)indolin-5-yl)acetic acid::CHEMBL207690 Oxysterols receptor LXR-beta 140 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184257&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11583743 104068651 CHEMBL207690 ZINC35863073 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135501 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)c(c2)C(F)(F)F)ccc2c(noc12)C(F)(F)F InChI=1S/C24H24F6N2O4/c1-3-5-16-19(9-8-17-21(16)36-31-22(17)24(28,29)30)35-11-4-10-32(2)15-7-6-14(12-20(33)34)18(13-15)23(25,26)27/h6-9,13H,3-5,10-12H2,1-2H3,(H,33,34) XNZXFVFJRAJUDY-UHFFFAOYSA-N 50184250 2-(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)-2-(trifluoromethyl)phenyl)acetic acid::CHEMBL382789 Oxysterols receptor LXR-beta 1300 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184250&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44412006 104068644 CHEMBL382789 ZINC37866920 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135502 CCCc1c(OCCCN(CC)c2ccc(CC(O)=O)cc2)ccc2c(noc12)C(F)(F)F InChI=1S/C24H27F3N2O4/c1-3-6-18-20(12-11-19-22(18)33-28-23(19)24(25,26)27)32-14-5-13-29(4-2)17-9-7-16(8-10-17)15-21(30)31/h7-12H,3-6,13-15H2,1-2H3,(H,30,31) DHBTWYCRACDCDH-UHFFFAOYSA-N 50184266 2-(4-(ethyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL208711 Oxysterols receptor LXR-beta 140 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184266&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411789 104068660 CHEMBL208711 C03768 ZINC37866924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135503 CCCc1c(OCCCNc2ccc(CC(O)=O)cc2)ccc2c(noc12)C(F)(F)F InChI=1S/C22H23F3N2O4/c1-2-4-16-18(10-9-17-20(16)31-27-21(17)22(23,24)25)30-12-3-11-26-15-7-5-14(6-8-15)13-19(28)29/h5-10,26H,2-4,11-13H2,1H3,(H,28,29) SUSIJEPKDLCOFC-UHFFFAOYSA-N 50184274 2-(4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylamino)phenyl)acetic acid::CHEMBL207103 Oxysterols receptor LXR-beta 89 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184274&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411843 104068668 CHEMBL207103 C03768 ZINC34717664 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135505 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)c(Cl)c2)ccc2c(noc12)C(F)(F)F InChI=1S/C23H24ClF3N2O4/c1-3-5-16-19(9-8-17-21(16)33-28-22(17)23(25,26)27)32-11-4-10-29(2)15-7-6-14(12-20(30)31)18(24)13-15/h6-9,13H,3-5,10-12H2,1-2H3,(H,30,31) JRJIJEXVKDFRTL-UHFFFAOYSA-N 50184259 2-(2-chloro-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL208967 Oxysterols receptor LXR-beta 124 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184259&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44412005 104068653 CHEMBL208967 ZINC37866921 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135509 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)cc2)ccc2c(noc12)C(F)(F)F InChI=1S/C23H25F3N2O4/c1-3-5-17-19(11-10-18-21(17)32-27-22(18)23(24,25)26)31-13-4-12-28(2)16-8-6-15(7-9-16)14-20(29)30/h6-11H,3-5,12-14H2,1-2H3,(H,29,30) FAQHMFAPRWBDDB-UHFFFAOYSA-N 50184254 2-(4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL207019 Oxysterols receptor LXR-beta 25 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184254&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411842 104068648 CHEMBL207019 C03768 ZINC34717660 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135513 CCCc1c(OCCCN(C)c2ccc(CC(O)=O)c(C)c2)ccc2c(noc12)C(F)(F)F InChI=1S/C24H27F3N2O4/c1-4-6-18-20(10-9-19-22(18)33-28-23(19)24(25,26)27)32-12-5-11-29(3)17-8-7-16(14-21(30)31)15(2)13-17/h7-10,13H,4-6,11-12,14H2,1-3H3,(H,30,31) AVSJVGZIDNEDSK-UHFFFAOYSA-N 50184256 2-(2-methyl-4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)phenyl)acetic acid::CHEMBL427040 Oxysterols receptor LXR-beta 26 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184256&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44412195 104068650 CHEMBL427040 ZINC34717665 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135515 CCCc1c(OCCCn2ccc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C24H23F3N2O4/c1-2-4-17-20(8-6-18-22(17)33-28-23(18)24(25,26)27)32-12-3-10-29-11-9-16-13-15(14-21(30)31)5-7-19(16)29/h5-9,11,13H,2-4,10,12,14H2,1H3,(H,30,31) VPVFJCQJGDFRIA-UHFFFAOYSA-N 50184255 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-indol-5-yl)acetic acid::CHEMBL383728 Oxysterols receptor LXR-beta 450 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184255&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11669781 104068649 CHEMBL383728 ZINC34717663 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135518 CCCc1c(OCCCN(C)c2ccc(cc2)C(O)=O)ccc2c(noc12)C(F)(F)F InChI=1S/C22H23F3N2O4/c1-3-5-16-18(11-10-17-19(16)31-26-20(17)22(23,24)25)30-13-4-12-27(2)15-8-6-14(7-9-15)21(28)29/h6-11H,3-5,12-13H2,1-2H3,(H,28,29) PNGBFYGVOOVAIY-UHFFFAOYSA-N 50184251 4-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)benzoic acid::CHEMBL207142 Oxysterols receptor LXR-beta 5100 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184251&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11697813 104068645 CHEMBL207142 ZINC38157665 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135521 CCCc1c(OCCCN(C)c2ncc(CC(O)=O)s2)ccc2c(noc12)C(F)(F)F InChI=1S/C20H22F3N3O4S/c1-3-5-13-15(7-6-14-17(13)30-25-18(14)20(21,22)23)29-9-4-8-26(2)19-24-11-12(31-19)10-16(27)28/h6-7,11H,3-5,8-10H2,1-2H3,(H,27,28) OVJGYBFXJVQSHK-UHFFFAOYSA-N 50184264 2-(2-(methyl(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)amino)thiazol-5-yl)acetic acid::CHEMBL381064 Oxysterols receptor LXR-beta 650 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184264&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11525365 104068658 CHEMBL381064 ZINC38157661 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135523 CCCc1c(OCCCn2cnc3cc(CC(O)=O)ccc23)ccc2c(noc12)C(F)(F)F InChI=1S/C23H22F3N3O4/c1-2-4-15-19(8-6-16-21(15)33-28-22(16)23(24,25)26)32-10-3-9-29-13-27-17-11-14(12-20(30)31)5-7-18(17)29/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,30,31) GMKDRYOJWQXLTE-UHFFFAOYSA-N 50184275 2-(1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)-1H-benzo[d]imidazol-5-yl)acetic acid::CHEMBL210613 Oxysterols receptor LXR-beta 410 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184275&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11655554 104068669 CHEMBL210613 ZINC37866923 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135524 CCCc1c(OCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)C(F)(F)F InChI=1S/C22H22F3NO5/c1-2-4-16-18(10-9-17-20(16)31-26-21(17)22(23,24)25)30-12-3-11-29-15-7-5-14(6-8-15)13-19(27)28/h5-10H,2-4,11-13H2,1H3,(H,27,28) SYPXZIFSIJUYCS-UHFFFAOYSA-N 50184261 2-(4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propoxy)phenyl)acetic acid::CHEMBL210973 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184261&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44411661 104068655 CHEMBL210973 C03768 ZINC34717666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50135526 CCCc1c(OCCCN2C(=O)Cc3cc(ccc23)C(O)=O)ccc2c(noc12)C(F)(F)F InChI=1S/C23H21F3N2O5/c1-2-4-15-18(8-6-16-20(15)33-27-21(16)23(24,25)26)32-10-3-9-28-17-7-5-13(22(30)31)11-14(17)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,30,31) JBHHUSIDAMWIJB-UHFFFAOYSA-N 50184262 2-oxo-1-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propyl)indoline-5-carboxylic acid::CHEMBL207382 Oxysterols receptor LXR-beta 4400 ChEMBL 10.1016/j.bmcl.2006.02.050 10.7270/Q20V8CD6 16529931 Szewczyk, JW; Huang, S; Chin, J; Tian, J; Mitnaul, L; Rosa, RL; Peterson, L; Sparrow, CP; Adams, AD Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184262&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11655575 104068656 CHEMBL207382 ZINC38157664 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50142285 CCCCCCc1ccccc1N1C(=O)c2ccccc2C1=O InChI=1S/C20H21NO2/c1-2-3-4-5-10-15-11-6-9-14-18(15)21-19(22)16-12-7-8-13-17(16)20(21)23/h6-9,11-14H,2-5,10H2,1H3 USXHUJLIZBGCGH-UHFFFAOYSA-N 23841 2-(2-hexylphenyl)-2,3-dihydro-1H-isoindole-1,3-dione::CHEMBL245943::PP60 Oxysterols receptor LXR-beta 65000 ChEMBL 10.1016/j.bmcl.2007.04.090 10.7270/Q2WS8SZQ 17498949 Noguchi-Yachide, T; Aoyama, A; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23841&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10638446 50092093 CHEMBL245943 ZINC28898280 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50142286 O=C1N(C(=O)c2ccccc12)c1ccccc1CCc1ccccc1 InChI=1S/C22H17NO2/c24-21-18-11-5-6-12-19(18)22(25)23(21)20-13-7-4-10-17(20)15-14-16-8-2-1-3-9-16/h1-13H,14-15H2 XGSWAPNRKGOSKD-UHFFFAOYSA-N 23840 2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindole-1,3-dione::CHEMBL246144::PP2P Oxysterols receptor LXR-beta 44000 ChEMBL 10.1016/j.bmcl.2007.04.090 10.7270/Q2WS8SZQ 17498949 Noguchi-Yachide, T; Aoyama, A; Makishima, M; Miyachi, H; Hashimoto, Y University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23840&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10616182 50092092 CHEMBL246144 ZINC28898291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145695 CC(C)(C)c1ccc(CC(C(O)=O)c2ccc(COc3cccc(c3)-c3ccc(c4ncc(cc34)C(=O)c3ccccc3)C(F)(F)F)cc2)cc1 InChI=1S/C43H36F3NO4/c1-42(2,3)33-18-14-27(15-19-33)22-36(41(49)50)29-16-12-28(13-17-29)26-51-34-11-7-10-31(23-34)35-20-21-38(43(44,45)46)39-37(35)24-32(25-47-39)40(48)30-8-5-4-6-9-30/h4-21,23-25,36H,22,26H2,1-3H3,(H,49,50) PGKSRZMWYJNXAT-UHFFFAOYSA-N 50227150 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)-3-(4-tert-butylphenyl)propanoic acid::CHEMBL253730 Oxysterols receptor LXR-beta 81 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227150&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446239 104097336 CHEMBL253730 ZINC28978732 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145696 OC(=O)C(Cc1ccc(cc1)-c1ccccc1)c1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C45H32F3NO4/c46-45(47,48)41-23-22-38(40-26-36(27-49-42(40)41)43(50)34-10-5-2-6-11-34)35-12-7-13-37(25-35)53-28-30-16-20-33(21-17-30)39(44(51)52)24-29-14-18-32(19-15-29)31-8-3-1-4-9-31/h1-23,25-27,39H,24,28H2,(H,51,52) DNNYNSPBJXNYMZ-UHFFFAOYSA-N 50227155 2-{4-[3-(3-benzoyl-8-trifluoromethyl-quinolin-5-yl)-phenoxymethyl]-phenyl}-3-biphenyl-4-yl-propionic acid::CHEMBL254335 Oxysterols receptor LXR-beta 473 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227155&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446242 104097341 CHEMBL254335 ZINC28978749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145697 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145698 CC#CCC(C(O)=O)c1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C36H26F3NO4/c1-2-3-12-30(35(42)43)24-15-13-23(14-16-24)22-44-28-11-7-10-26(19-28)29-17-18-32(36(37,38)39)33-31(29)20-27(21-40-33)34(41)25-8-5-4-6-9-25/h4-11,13-21,30H,12,22H2,1H3,(H,42,43) SBYNVOVSJLOHRE-UHFFFAOYSA-N 50227163 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)hex-4-ynoic acid::CHEMBL254539 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227163&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446246 104097349 CHEMBL254539 ZINC28978771 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145699 OC(=O)C(CC=C)c1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C35H26F3NO4/c1-2-7-29(34(41)42)23-14-12-22(13-15-23)21-43-27-11-6-10-25(18-27)28-16-17-31(35(36,37)38)32-30(28)19-26(20-39-32)33(40)24-8-4-3-5-9-24/h2-6,8-20,29H,1,7,21H2,(H,41,42) LCDRBOYRRKJMEX-UHFFFAOYSA-N 50227160 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)pent-4-enoic acid::CHEMBL403958 Oxysterols receptor LXR-beta 5 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227160&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446244 104097346 CHEMBL403958 ZINC28978761 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145700 Cc1cc(OCc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c(C)cc1CC(O)=O InChI=1S/C34H28F3NO3/c1-21-15-30(22(2)14-26(21)18-31(39)40)41-20-24-10-6-11-25(17-24)32-27(16-23-8-4-3-5-9-23)19-38-33-28(32)12-7-13-29(33)34(35,36)37/h3-15,17,19H,16,18,20H2,1-2H3,(H,39,40) NVCNWULYEHGNKG-UHFFFAOYSA-N 50227158 2-(4-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzyloxy)-2,5-dimethylphenyl)acetic acid::CHEMBL404468 Oxysterols receptor LXR-beta 4 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227158&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25227247 104097344 CHEMBL404468 ZINC28978841 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145701 Cc1cc(NCc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c(C)cc1CC(O)=O InChI=1S/C34H29F3N2O2/c1-21-15-30(22(2)14-26(21)18-31(40)41)38-19-24-10-6-11-25(17-24)32-27(16-23-8-4-3-5-9-23)20-39-33-28(32)12-7-13-29(33)34(35,36)37/h3-15,17,20,38H,16,18-19H2,1-2H3,(H,40,41) LFYZXWABUGTSOT-UHFFFAOYSA-N 50227146 2-(4-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)-2,5-dimethylphenyl)acetic acid::CHEMBL403418 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227146&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25226881 104097332 CHEMBL403418 ZINC28978860 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145702 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta 90 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145704 Cc1c(C)c(NCc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)ccc1CC(O)=O InChI=1S/C34H29F3N2O2/c1-21-22(2)30(15-14-25(21)18-31(40)41)38-19-24-10-6-11-26(17-24)32-27(16-23-8-4-3-5-9-23)20-39-33-28(32)12-7-13-29(33)34(35,36)37/h3-15,17,20,38H,16,18-19H2,1-2H3,(H,40,41) GCAJNTSVNKDATQ-UHFFFAOYSA-N 50227159 2-(4-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)-2,3-dimethylphenyl)acetic acid::CHEMBL253521 Oxysterols receptor LXR-beta 4 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227159&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25226691 104097345 CHEMBL253521 ZINC28978870 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145705 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 9 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145706 CCC#CCC(C(O)=O)c1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C37H28F3NO4/c1-2-3-5-13-31(36(43)44)25-16-14-24(15-17-25)23-45-29-12-8-11-27(20-29)30-18-19-33(37(38,39)40)34-32(30)21-28(22-41-34)35(42)26-9-6-4-7-10-26/h4,6-12,14-22,31H,2,13,23H2,1H3,(H,43,44) YPXOOPFXOOABHI-UHFFFAOYSA-N 50227154 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)hept-4-ynoic acid::CHEMBL254541 Oxysterols receptor LXR-beta 10 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227154&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446249 104097340 CHEMBL254541 ZINC28978784 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145707 OC(=O)C(CC#C)(CC#C)c1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C38H26F3NO4/c1-3-19-37(20-4-2,36(44)45)29-15-13-25(14-16-29)24-46-30-12-8-11-27(21-30)31-17-18-33(38(39,40)41)34-32(31)22-28(23-42-34)35(43)26-9-6-5-7-10-26/h1-2,5-18,21-23H,19-20,24H2,(H,44,45) ZXTASCJKIFSEGC-UHFFFAOYSA-N 50227157 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)-2-(prop-2-ynyl)pent-4-ynoic acid::CHEMBL254542 Oxysterols receptor LXR-beta 26 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227157&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446254 104097343 CHEMBL254542 ZINC28978809 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145708 CCC#CCC(CC#CCC)(C(O)=O)c1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C42H34F3NO4/c1-3-5-10-23-41(40(48)49,24-11-6-4-2)33-19-17-29(18-20-33)28-50-34-16-12-15-31(25-34)35-21-22-37(42(43,44)45)38-36(35)26-32(27-46-38)39(47)30-13-8-7-9-14-30/h7-9,12-22,25-27H,3-4,23-24,28H2,1-2H3,(H,48,49) DCFHWWUSMITHJJ-UHFFFAOYSA-N 50227149 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)-2-(pent-2-ynyl)hept-4-ynoic acid::CHEMBL404036 Oxysterols receptor LXR-beta 219 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227149&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446253 104097335 CHEMBL404036 ZINC28978803 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145709 Cc1cc(CC(O)=O)c(C)cc1COc1cccc(c1)-c1c(Cc2ccccc2)cnc2c(cccc12)C(F)(F)F InChI=1S/C34H28F3NO3/c1-21-15-27(22(2)14-25(21)18-31(39)40)20-41-28-11-6-10-24(17-28)32-26(16-23-8-4-3-5-9-23)19-38-33-29(32)12-7-13-30(33)34(35,36)37/h3-15,17,19H,16,18,20H2,1-2H3,(H,39,40) AAXKPQBGHZNCOJ-UHFFFAOYSA-N 50227156 2-(4-((3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)phenoxy)methyl)-2,5-dimethylphenyl)acetic acid::CHEMBL254945 Oxysterols receptor LXR-beta 3 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227156&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25225786 104097342 CHEMBL254945 ZINC28978833 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145710 OC(=O)Cc1cccc2c(NCc3cccc(c3)-c3ccnc4c(cccc34)C(F)(F)F)cccc12 InChI=1S/C29H21F3N2O2/c30-29(31,32)25-11-3-10-24-22(13-14-33-28(24)25)19-6-1-5-18(15-19)17-34-26-12-4-8-21-20(16-27(35)36)7-2-9-23(21)26/h1-15,34H,16-17H2,(H,35,36) YLJKCCPSAPDTDJ-UHFFFAOYSA-N 50227147 2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid::CHEMBL253731 Oxysterols receptor LXR-beta 622 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227147&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24936148 104097333 CHEMBL253731 ZINC28978905 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145711 OC(=O)Cc1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C32H22F3NO4/c33-32(34,35)28-14-13-26(27-17-24(18-36-30(27)28)31(39)22-5-2-1-3-6-22)23-7-4-8-25(16-23)40-19-21-11-9-20(10-12-21)15-29(37)38/h1-14,16-18H,15,19H2,(H,37,38) LIKCFBAAJFMUJP-UHFFFAOYSA-N 50227162 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)acetic acid::CHEMBL254333 Oxysterols receptor LXR-beta 5 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227162&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446235 104097348 CHEMBL254333 C03768 ZINC28978707 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145712 Cc1cnc2c(cccc2c1-c1cccc(CNc2cccc3c(CC(O)=O)cccc23)c1)C(F)(F)F InChI=1S/C30H23F3N2O2/c1-18-16-35-29-24(11-4-12-25(29)30(31,32)33)28(18)21-8-2-6-19(14-21)17-34-26-13-5-9-22-20(15-27(36)37)7-3-10-23(22)26/h2-14,16,34H,15,17H2,1H3,(H,36,37) OHDRXCKGYPYQAU-UHFFFAOYSA-N 50227145 2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid::CHEMBL442437 Oxysterols receptor LXR-beta 4167 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227145&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24936147 104097331 CHEMBL442437 ZINC28978899 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145713 OC(=O)Cc1ccc(NCc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c2ccccc12 InChI=1S/C36H27F3N2O2/c37-36(38,39)31-15-7-14-30-34(27(22-41-35(30)31)18-23-8-2-1-3-9-23)26-11-6-10-24(19-26)21-40-32-17-16-25(20-33(42)43)28-12-4-5-13-29(28)32/h1-17,19,22,40H,18,20-21H2,(H,42,43) UUIQBDLORYXQJP-UHFFFAOYSA-N 50227161 2-(4-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)naphthalen-1-yl)acetic acid::CHEMBL404469 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227161&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25227069 104097347 CHEMBL404469 ZINC28978892 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145714 OC(=O)Cc1cccc2c(OCc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)cccc12 InChI=1S/C36H26F3NO3/c37-36(38,39)31-16-6-15-30-34(27(21-40-35(30)31)18-23-8-2-1-3-9-23)26-12-4-10-24(19-26)22-43-32-17-7-13-28-25(20-33(41)42)11-5-14-29(28)32/h1-17,19,21H,18,20,22H2,(H,41,42) BHKSYENPDNOBLX-UHFFFAOYSA-N 50227152 2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzyloxy)naphthalen-1-yl)acetic acid::CHEMBL404265 Oxysterols receptor LXR-beta 11 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227152&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25226692 104097338 CHEMBL404265 ZINC28978883 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145715 OC(=O)Cc1cccc2c(NCc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)cccc12 InChI=1S/C36H27F3N2O2/c37-36(38,39)31-16-6-15-30-34(27(22-41-35(30)31)18-23-8-2-1-3-9-23)26-12-4-10-24(19-26)21-40-32-17-7-13-28-25(20-33(42)43)11-5-14-29(28)32/h1-17,19,22,40H,18,20-21H2,(H,42,43) FMNHPFYLVZKAJK-UHFFFAOYSA-N 50227151 2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)naphthalen-1-yl)acetic acid::CHEMBL253311 Oxysterols receptor LXR-beta 355 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227151&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24936142 104097337 CHEMBL253311 ZINC28978878 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145716 OC(=O)Cc1cccc2c(NCc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)cccc12 InChI=1S/C36H27F3N2O2/c37-36(38,39)31-16-6-15-30-34(27(22-41-35(30)31)18-23-8-2-1-3-9-23)26-12-4-10-24(19-26)21-40-32-17-7-13-28-25(20-33(42)43)11-5-14-29(28)32/h1-17,19,22,40H,18,20-21H2,(H,42,43) FMNHPFYLVZKAJK-UHFFFAOYSA-N 50227151 2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)naphthalen-1-yl)acetic acid::CHEMBL253311 Oxysterols receptor LXR-beta 5 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227151&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24936142 104097337 CHEMBL253311 ZINC28978878 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145717 OC(=O)C(Cc1ccccc1)c1ccc(COc2cccc(c2)-c2ccc(c3ncc(cc23)C(=O)c2ccccc2)C(F)(F)F)cc1 InChI=1S/C39H28F3NO4/c40-39(41,42)35-19-18-32(34-22-30(23-43-36(34)35)37(44)28-10-5-2-6-11-28)29-12-7-13-31(21-29)47-24-26-14-16-27(17-15-26)33(38(45)46)20-25-8-3-1-4-9-25/h1-19,21-23,33H,20,24H2,(H,45,46) GXMUAXSMPDAKHA-UHFFFAOYSA-N 50227153 2-(4-((3-(3-benzoyl-8-(trifluoromethyl)quinolin-5-yl)phenoxy)methyl)phenyl)-3-phenylpropanoic acid::CHEMBL253398 Oxysterols receptor LXR-beta 67 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227153&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44446237 104097339 CHEMBL253398 ZINC28978719 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145718 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 178 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145720 OC(=O)Cc1cccc2c(NCc3cccc(c3)-c3ccnc4c(cccc34)C(F)(F)F)cccc12 InChI=1S/C29H21F3N2O2/c30-29(31,32)25-11-3-10-24-22(13-14-33-28(24)25)19-6-1-5-18(15-19)17-34-26-12-4-8-21-20(16-27(35)36)7-2-9-23(21)26/h1-15,34H,16-17H2,(H,35,36) YLJKCCPSAPDTDJ-UHFFFAOYSA-N 50227147 2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid::CHEMBL253731 Oxysterols receptor LXR-beta 15 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227147&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24936148 104097333 CHEMBL253731 ZINC28978905 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145721 Cc1cnc2c(cccc2c1-c1cccc(CNc2cccc3c(CC(O)=O)cccc23)c1)C(F)(F)F InChI=1S/C30H23F3N2O2/c1-18-16-35-29-24(11-4-12-25(29)30(31,32)33)28(18)21-8-2-6-19(14-21)17-34-26-13-5-9-22-20(15-27(36)37)7-3-10-23(22)26/h2-14,16,34H,15,17H2,1H3,(H,36,37) OHDRXCKGYPYQAU-UHFFFAOYSA-N 50227145 2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid::CHEMBL442437 Oxysterols receptor LXR-beta 10 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227145&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24936147 104097331 CHEMBL442437 ZINC28978899 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145722 OC(=O)c1cccc2c(NCc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)cccc12 InChI=1S/C35H25F3N2O2/c36-35(37,38)30-16-6-15-29-32(25(21-40-33(29)30)18-22-8-2-1-3-9-22)24-11-4-10-23(19-24)20-39-31-17-7-12-26-27(31)13-5-14-28(26)34(41)42/h1-17,19,21,39H,18,20H2,(H,41,42) KJPPQVNZYDPQRM-UHFFFAOYSA-N 50227148 5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)-1-naphthoic acid::CHEMBL253312 Oxysterols receptor LXR-beta 35 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227148&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25225010 104097334 CHEMBL253312 ZINC28978895 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50145725 OC(=O)Cc1ccc(NCc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-9-4-8-23(17-24)19-36-26-14-12-22(13-15-26)18-29(38)39/h1-15,17,20,36H,16,18-19H2,(H,38,39) SENBJMMSGVHUDH-UHFFFAOYSA-N 20002 2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]phenyl}acetic acid::CHEMBL216645::Quinoline 17 Oxysterols receptor LXR-beta 7 ChEMBL 10.1016/j.bmcl.2007.11.013 10.7270/Q2N879JT 18023179 Hu, B; Quinet, E; Unwalla, R; Collini, M; Jetter, J; Dooley, R; Andraka, D; Nogle, L; Savio, D; Halpern, A; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20002&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16090331 46519997 CHEMBL216645 C03768 ZINC14972496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146946 CC(C)=CCC\C(C)=C\C[C@H]1C[C@@]2(CC=C(C)C)C(=O)C(C(=O)c3ccc(O)c(O)c3)C(=O)[C@](CC=C(C)C)(C2=O)[C@]1(C)CCC=C(C)C InChI=1S/C43H58O6/c1-27(2)13-11-15-31(9)16-18-33-26-42(23-20-29(5)6)38(47)36(37(46)32-17-19-34(44)35(45)25-32)39(48)43(40(42)49,24-21-30(7)8)41(33,10)22-12-14-28(3)4/h13-14,16-17,19-21,25,33,36,44-45H,11-12,15,18,22-24,26H2,1-10H3/b31-16+/t33-,36?,41+,42-,43+/m0/s1 ZYVWXOBUNTVJCF-ANEFFXJWSA-N 50269497 CHEMBL445689::Guttiferone I Oxysterols receptor LXR-beta >15000 ChEMBL 10.1021/np050045j 10.7270/Q24749MK 15844964 Herath, K; Jayasuriya, H; Ondeyka, JG; Guan, Z; Borris, RP; Stijfhoorn, E; Stevenson, D; Wang, J; Sharma, N; Macnaul, K; Menke, JG; Ali, A; Schulman, MJ; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269497&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91935151 104115191 CHEMBL445689 ZINC49823223 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146947 CC(C)CC[C@@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1 RZPAXNJLEKLXNO-GFKLAVDKSA-N 20177 (1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::22(R)-hydroxycholesterol::CHEMBL422904 Oxysterols receptor LXR-beta >15000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20177&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search HC9 3N9Z,3MZS,3L0J 167685 49688252 67237 CHEMBL422904 2742 C05502 ZINC04096816 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146948 C[C@@]1(CC=C2[C@@H](CC[C@@H]3[C@@](C)(CCC[C@@]23C)C(=O)NCC23CC4CC(CC(C4)C2)C3)C1)C=C InChI=1S/C31H47NO/c1-5-28(2)12-9-25-24(19-28)7-8-26-29(25,3)10-6-11-30(26,4)27(33)32-20-31-16-21-13-22(17-31)15-23(14-21)18-31/h5,9,21-24,26H,1,6-8,10-20H2,2-4H3,(H,32,33)/t21?,22?,23?,24-,26-,28-,29-,30+,31?/m0/s1 PQFNGPLIFDHHQQ-PMFBIFCRSA-N 50241904 (1R,4aR,7S,8aS,10aS)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid (adamantan-1-ylmethyl)-amide::CHEMBL521375 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241904&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44559244 104098894 CHEMBL521375 ZINC40424020 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146949 CC(=O)Oc1ccc2CC[C@H]3[C@](C)(CCC[C@]3(C)c2c1)C(=O)OC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(OC(C)=O)cc21 InChI=1S/C38H46O7/c1-23(39)43-27-13-9-25-11-15-31-35(3,29(25)21-27)17-7-19-37(31,5)33(41)45-34(42)38(6)20-8-18-36(4)30-22-28(44-24(2)40)14-10-26(30)12-16-32(36)38/h9-10,13-14,21-22,31-32H,7-8,11-12,15-20H2,1-6H3/t31-,32-,35-,36-,37+,38+/m1/s1 OUJQRQRBNRGQTC-SPGSYPTKSA-N 50241903 CHEMBL506838::acetyl Podocarpic acid anhydride Oxysterols receptor LXR-beta <3 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241903&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9830426 104098893 CHEMBL506838 2753 ZINC38149326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146950 C[C@H](CC\C=C(/C)C(O)=O)[C@H]1CC[C@@]2(C)[C@@H]3CC=C4[C@@H](CC[C@@H](O)C4(C)C)[C@]3(C)CC[C@]12C InChI=1S/C30H48O3/c1-19(9-8-10-20(2)26(32)33)21-15-16-30(7)24-13-11-22-23(12-14-25(31)27(22,3)4)28(24,5)17-18-29(21,30)6/h10-11,19,21,23-25,31H,8-9,12-18H2,1-7H3,(H,32,33)/b20-10+/t19-,21-,23-,24-,25-,28+,29-,30+/m1/s1 JMOPTHLWCJXLBX-IJAJUTMCSA-N 50241887 CHEMBL487001::Rosacea acid B Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241887&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44559230 104098889 CHEMBL487001 ZINC45496405 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146951 CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO4S/c1-2-4-14-17(7-6-15-20(14)31-27-21(15)22(24,25)26)30-9-3-10-32-18-8-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) TZBRFAASYWFUGK-UHFFFAOYSA-N 50126018 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid::CHEMBL23296::{3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid::{3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)sulfanyl]phenyl}acetic acid Oxysterols receptor LXR-beta 16 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O90 3IPS 9935197 104018161 CHEMBL23296 2688 ZINC03834054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146952 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NCC12CC3CC(CC(C3)C1)C2 InChI=1S/C28H39NO2/c1-26-8-3-9-27(2,24(26)7-5-21-4-6-22(30)13-23(21)26)25(31)29-17-28-14-18-10-19(15-28)12-20(11-18)16-28/h4,6,13,18-20,24,30H,3,5,7-12,14-17H2,1-2H3,(H,29,31)/t18?,19?,20?,24-,26-,27+,28?/m1/s1 DHBIWVAWNUNKJG-WPKHNGPTSA-N 50172185 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (adamantan-1-ylmethyl)-amide::(4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (adamantan-1-ylmethyl)-amide::CHEMBL194642 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172185&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10070833 104058314 CHEMBL194642 ZINC28526438 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146953 C[C@H](CCC=C(C)C)[C@H]1C[C@H](O)[C@@]2(C)C3=CC[C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)C3=CC[C@]12C InChI=1S/C30H48O2/c1-19(2)10-9-11-20(3)23-18-26(32)30(8)22-12-13-24-27(4,5)25(31)15-16-28(24,6)21(22)14-17-29(23,30)7/h10,12,14,20,23-26,31-32H,9,11,13,15-18H2,1-8H3/t20-,23-,24+,25+,26+,28-,29-,30-/m1/s1 CCFQLQIYEHITNK-SSORVZQWSA-N 50241886 (3S,5R,10S,13R,14R,15S,17R)-4,4,10,13,14-pentamethyl-17-((R)-6-methylhept-5-en-2-yl)-2,3,4,5,6,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,15-diol::CHEMBL486808 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241886&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11697907 104098888 CHEMBL486808 ZINC06036292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146954 C[C@@]1(CC=C2[C@@H](CC[C@@H]3[C@](C)(CO)CCC[C@@]23C)C1)C=C InChI=1S/C20H32O/c1-5-18(2)12-9-16-15(13-18)7-8-17-19(3,14-21)10-6-11-20(16,17)4/h5,9,15,17,21H,1,6-8,10-14H2,2-4H3/t15-,17+,18-,19-,20-/m0/s1 YSFNIVKHYKBKHI-ZDNSCYFHSA-N 50241877 ((1R,4aR,7S,8aS,10aS)-1,4a,7-trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydrophenanthren-1-yl)methanol::CHEMBL470040 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241877&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 14239481 104098886 CHEMBL470040 ZINC27099805 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146955 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(O)=O InChI=1S/C17H22O3/c1-16-8-3-9-17(2,15(19)20)14(16)7-5-11-4-6-12(18)10-13(11)16/h4,6,10,14,18H,3,5,7-9H2,1-2H3,(H,19,20)/t14-,16-,17+/m1/s1 VJILEYKNALCDDV-OIISXLGYSA-N 50167696 (1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydroxy-1,4a-dimethylphenanthrene-1-carboxylic acid::(1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid::12-hydroxypodocarpa-8,11,13-trien-16-oic acid::CHEMBL421115::Podocarpic acid Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167696&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 93017 104052912 8277 CHEMBL421115 C09171 ZINC03947415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146956 C[C@@]1(CC=C2[C@@H](CC[C@@H]3[C@@](C)(CCC[C@@]23C)C(O)=O)C1)C=C InChI=1S/C20H30O2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h5,9,14,16H,1,6-8,10-13H2,2-4H3,(H,21,22)/t14-,16-,18-,19-,20+/m0/s1 TVHDZSRRHQKNEZ-MGFONVBGSA-N 50241876 (-)-Acanthoic acid::CHEMBL512490 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241876&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9817887 104098885 CHEMBL512490 ZINC27639706 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146957 CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1 QGJZLNKBHJESQX-FZFNOLFKSA-N 23208 (1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosane-5-carboxylic acid::Betulinic Acid, 24::CHEMBL269277::cid_64971 Oxysterols receptor LXR-beta >50000 ChEMBL 10.1021/np050182g 10.7270/Q2GH9HQ5 16124770 Jayasuriya, H; Herath, KB; Ondeyka, JG; Guan, Z; Borris, RP; Tiwari, S; de Jong, W; Chavez, F; Moss, J; Stevenson, DW; Beck, HT; Slattery, M; Zamora, N; Schulman, M; Ali, A; Sharma, N; MacNaul, K; Hayes, N; Menke, JG; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23208&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 06L 64971 49847021 3087 CHEMBL269277 3945 C08619 ZINC04097714 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146958 Cc1cc(O)cc2O[C@@]3(C)Cc4cc5c(C(=O)c6c(O)cc(O)cc6C5(C)C)c(O)c4[C@H](O3)c12 InChI=1S/C27H24O7/c1-11-5-13(28)9-18-19(11)25-20-12(10-27(4,33-18)34-25)6-15-22(23(20)31)24(32)21-16(26(15,2)3)7-14(29)8-17(21)30/h5-9,25,28-31H,10H2,1-4H3/t25?,27-/m1/s1 MDUGEFRGUDVHQH-ZCJYOONXSA-N 50250483 (-)-anthrabenzoxocinone::CHEMBL465148 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1021/np050176k 10.7270/Q270816X 16180833 Herath, KB; Jayasuriya, H; Guan, Z; Schulman, M; Ruby, C; Sharma, N; MacNaul, K; Menke, JG; Kodali, S; Galgoci, A; Wang, J; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250483&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11604995 104104223 65474 CHEMBL465148 ZINC09574742 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50146959 COc1cc(C)c2[C@H]3O[C@](C)(Cc4cc5c(C(=O)c6c(O)c(Cl)c(O)c(Cl)c6C5(C)C)c(O)c34)Oc2c1 InChI=1S/C28H24Cl2O7/c1-10-6-12(35-5)8-14-15(10)26-16-11(9-28(4,36-14)37-26)7-13-17(22(16)31)23(32)18-19(27(13,2)3)20(29)25(34)21(30)24(18)33/h6-8,26,31,33-34H,9H2,1-5H3/t26?,28-/m1/s1 ZGJMIZXNGYVIRM-SVNIRARHSA-N 50250484 (-)-bischloroanthrabenzoxocinone::CHEMBL463906 Oxysterols receptor LXR-beta >15000 ChEMBL 10.1021/np050176k 10.7270/Q270816X 16180833 Herath, KB; Jayasuriya, H; Guan, Z; Schulman, M; Ruby, C; Sharma, N; MacNaul, K; Menke, JG; Kodali, S; Galgoci, A; Wang, J; Singh, SB Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250484&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11555706 104104224 CHEMBL463906 ZINC44386840 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156545 C[C@H](CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F InChI=1S/C34H33ClF3NO3/c1-24(18-19-42-29-16-8-10-25(20-29)21-32(40)41)39(22-28-15-9-17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41)/t24-/m1/s1 ZLJZDYOBXVOTSA-XMMPIXPASA-N 50300575 (R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid::CHEMBL573677 Oxysterols receptor LXR-beta 25 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300575&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10218693 104154936 CHEMBL573677 ZINC49695241 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156546 C[C@@H](CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F InChI=1S/C34H33ClF3NO3/c1-24(18-19-42-29-16-8-10-25(20-29)21-32(40)41)39(22-28-15-9-17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41)/t24-/m0/s1 ZLJZDYOBXVOTSA-DEOSSOPVSA-N 50300576 (S)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid::CHEMBL584364 Oxysterols receptor LXR-beta 87 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300576&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10218694 104154937 CHEMBL584364 ZINC49723210 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156547 OC(=O)Cc1ccc2oc(CCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cc2c1 InChI=1S/C34H29ClF3NO3/c35-33-26(12-7-13-30(33)34(36,37)38)21-39(22-29(24-8-3-1-4-9-24)25-10-5-2-6-11-25)17-16-28-20-27-18-23(19-32(40)41)14-15-31(27)42-28/h1-15,18,20,29H,16-17,19,21-22H2,(H,40,41) AANMNNSUDXTLGF-UHFFFAOYSA-N 50300574 2-(2-(2-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)ethyl)benzofuran-5-yl)acetic acid::CHEMBL573678 Oxysterols receptor LXR-beta 145 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300574&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9808622 104154935 CHEMBL573678 ZINC49695242 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156548 CC(C)(C(O)=O)c1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C35H35ClF3NO3/c1-34(2,33(41)42)28-17-10-18-29(22-28)43-21-11-20-40(23-27-16-9-19-31(32(27)36)35(37,38)39)24-30(25-12-5-3-6-13-25)26-14-7-4-8-15-26/h3-10,12-19,22,30H,11,20-21,23-24H2,1-2H3,(H,41,42) IAXOISXBOXYVMG-UHFFFAOYSA-N 50300572 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)-2-methylpropanoic acid::CHEMBL573679 Oxysterols receptor LXR-beta 15 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300572&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10312324 104154933 CHEMBL573679 ZINC49695243 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156549 OC(=O)Cc1ccc2cc(CCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)oc2c1 InChI=1S/C34H29ClF3NO3/c35-33-27(12-7-13-30(33)34(36,37)38)21-39(22-29(24-8-3-1-4-9-24)25-10-5-2-6-11-25)17-16-28-20-26-15-14-23(19-32(40)41)18-31(26)42-28/h1-15,18,20,29H,16-17,19,21-22H2,(H,40,41) ZCCZMYDWILRCGU-UHFFFAOYSA-N 50300573 2-(2-(2-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)ethyl)benzofuran-6-yl)acetic acid::CHEMBL584566 Oxysterols receptor LXR-beta 63 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300573&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10218669 104154934 CHEMBL584566 ZINC49723272 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156550 CCC(CC)(C(O)=O)c1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C37H39ClF3NO3/c1-3-36(4-2,35(43)44)30-19-12-20-31(24-30)45-23-13-22-42(25-29-18-11-21-33(34(29)38)37(39,40)41)26-32(27-14-7-5-8-15-27)28-16-9-6-10-17-28/h5-12,14-21,24,32H,3-4,13,22-23,25-26H2,1-2H3,(H,43,44) TYOGYVGOHLVBEF-UHFFFAOYSA-N 50300570 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)-2-ethylbutanoic acid::CHEMBL584567 Oxysterols receptor LXR-beta 174 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300570&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45483602 104154931 CHEMBL584567 ZINC49723273 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156551 CC(C(O)=O)c1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C34H33ClF3NO3/c1-24(33(40)41)27-15-8-17-29(21-27)42-20-10-19-39(22-28-16-9-18-31(32(28)35)34(36,37)38)23-30(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-9,11-18,21,24,30H,10,19-20,22-23H2,1H3,(H,40,41) AVNLUJALSLNPNX-UHFFFAOYSA-N 50300571 2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)phenyl)propanoic acid::CHEMBL573603 Oxysterols receptor LXR-beta 15 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300571&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10129169 104154932 CHEMBL573603 ZINC49695515 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156552 OC(=O)C1CCCc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 InChI=1S/C36H35ClF3NO3/c37-34-27(15-7-19-32(34)36(38,39)40)23-41(24-31(25-11-3-1-4-12-25)26-13-5-2-6-14-26)21-10-22-44-33-20-9-16-28-29(33)17-8-18-30(28)35(42)43/h1-7,9,11-16,19-20,30-31H,8,10,17-18,21-24H2,(H,42,43) OHQDOFBGVQTUAB-UHFFFAOYSA-N 50300568 (+/-)-5-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)propoxy)-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid::CHEMBL573680 Oxysterols receptor LXR-beta 26 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300568&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11181120 104154929 CHEMBL573680 ZINC49695484 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156553 C[C@@H](COc1cccc(CC(O)=O)c1)CN(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F InChI=1S/C34H33ClF3NO3/c1-24(23-42-29-16-8-10-25(18-29)19-32(40)41)20-39(21-28-15-9-17-31(33(28)35)34(36,37)38)22-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-18,24,30H,19-23H2,1H3,(H,40,41)/t24-/m1/s1 DMMRWDJRLGTEMM-XMMPIXPASA-N 50300579 (R)-2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl]-(2,2-diphenylethyl)amino]-2-methyl-propoxy}-phenyl)acetic acid::CHEMBL573587 Oxysterols receptor LXR-beta 86 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300579&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10196830 104154940 CHEMBL573587 ZINC49695102 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156554 C[C@H](CCOc1cccc(c1)C(C)(C)C(O)=O)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F InChI=1S/C36H37ClF3NO3/c1-25(20-21-44-30-18-11-17-29(22-30)35(2,3)34(42)43)41(23-28-16-10-19-32(33(28)37)36(38,39)40)24-31(26-12-6-4-7-13-26)27-14-8-5-9-15-27/h4-19,22,25,31H,20-21,23-24H2,1-3H3,(H,42,43)/t25-/m1/s1 DWBDSQMGSRVGMI-RUZDIDTESA-N 50300569 (R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butoxy)phenyl)-2-methylpropanoic acid::CHEMBL584568 Oxysterols receptor LXR-beta 11 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300569&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44626292 104154930 CHEMBL584568 ZINC49723274 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156555 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 40 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156556 C[C@H](CCN(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F)Oc1cccc(CC(O)=O)c1 InChI=1S/C34H33ClF3NO3/c1-24(42-29-16-8-10-25(20-29)21-32(40)41)18-19-39(22-28-15-9-17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41)/t24-/m1/s1 XFIORQLIQIPEBM-XMMPIXPASA-N 50300577 (R)-2-(3-(4-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butan-2-yloxy)phenyl)acetic acid::CHEMBL573651 Oxysterols receptor LXR-beta 41 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300577&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10129170 104154938 CHEMBL573651 ZINC49695239 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50156557 C[C@@H](CCN(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F)Oc1cccc(CC(O)=O)c1 InChI=1S/C34H33ClF3NO3/c1-24(42-29-16-8-10-25(20-29)21-32(40)41)18-19-39(22-28-15-9-17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41)/t24-/m0/s1 XFIORQLIQIPEBM-DEOSSOPVSA-N 50300578 (S)-2-(3-(4-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butan-2-yloxy)phenyl)acetic acid::CHEMBL573591 Oxysterols receptor LXR-beta 145 ChEMBL 10.1016/j.bmcl.2009.08.036 10.7270/Q20865CN 19717304 Marino, JP; Kallander, LS; Ma, C; Oh, HJ; Lee, D; Gaitanopoulos, DE; Krawiec, JA; Parks, DJ; Webb, CL; Ziegler, K; Jaye, M; Thompson, SK GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300578&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10312252 104154939 CHEMBL573591 ZINC49695187 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154381 Cn1c(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc2ccccc12 InChI=1S/C33H26F3N3/c1-39-27(19-23-11-5-6-16-30(23)39)21-37-26-13-7-12-24(18-26)31-25(17-22-9-3-2-4-10-22)20-38-32-28(31)14-8-15-29(32)33(34,35)36/h2-16,18-20,37H,17,21H2,1H3 MJGWHEJLSWUCNL-UHFFFAOYSA-N 50294738 CHEMBL551981::{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-[(1-methyl-1H-indol-2-yl)methyl]amine Oxysterols receptor LXR-beta 39000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45272392 104136269 CHEMBL551981 ZINC43021150 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154382 FC(F)(F)c1cccc(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1 InChI=1S/C29H20ClF3N2O/c30-25-14-6-13-24-27(26(34-35-28(24)25)16-19-7-2-1-3-8-19)21-10-5-12-23(17-21)36-18-20-9-4-11-22(15-20)29(31,32)33/h1-15,17H,16,18H2 VOOHWEWPJYDTGC-UHFFFAOYSA-N 50294747 3-Benzyl-8-chloro-4-(3-{[3-(trifluoromethyl)benzyl]-oxy}phenyl)cinnoline::CHEMBL564506 Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854315 104136278 CHEMBL564506 ZINC36479670 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154487 Fc1ccc(c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)c1)C(F)(F)F InChI=1S/C30H19F7N2O/c31-21-12-13-24(29(32,33)34)20(15-21)17-40-22-9-4-8-19(16-22)27-23-10-5-11-25(30(35,36)37)28(23)39-38-26(27)14-18-6-2-1-3-7-18/h1-13,15-16H,14,17H2 IKYMOODGQWULPF-UHFFFAOYSA-N 50294742 3-Benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline::CHEMBL550568 Oxysterols receptor LXR-beta 3650 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11853793 104136273 CHEMBL550568 ZINC43123232 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154488 FC(F)(F)c1cccc(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1Cl InChI=1S/C29H19Cl2F3N2O/c30-24-14-6-12-22-26(25(35-36-28(22)24)15-18-7-2-1-3-8-18)19-9-4-11-21(16-19)37-17-20-10-5-13-23(27(20)31)29(32,33)34/h1-14,16H,15,17H2 ZTRCQAWKQLDVDC-UHFFFAOYSA-N 50294744 3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)-benzyl]oxy}phenyl)cinnoline::CHEMBL550983 Oxysterols receptor LXR-beta 24000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854570 104136275 CHEMBL550983 ZINC43021609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154489 Fc1ccc(c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1)C(F)(F)F InChI=1S/C29H19ClF4N2O/c30-25-11-5-10-23-27(26(35-36-28(23)25)14-18-6-2-1-3-7-18)19-8-4-9-22(16-19)37-17-20-15-21(31)12-13-24(20)29(32,33)34/h1-13,15-16H,14,17H2 AKNPZPNNRMKRHE-UHFFFAOYSA-N 50294750 3-Benzyl-8-chloro-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl]oxy}phenyl)cinnoline::CHEMBL552310 Oxysterols receptor LXR-beta 44000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854314 104136281 CHEMBL552310 ZINC43120256 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154490 FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(NCc2cccc3cc[nH]c23)c1 InChI=1S/C32H24F3N3/c33-32(34,35)28-14-6-13-27-29(25(20-38-31(27)28)17-21-7-2-1-3-8-21)23-10-5-12-26(18-23)37-19-24-11-4-9-22-15-16-36-30(22)24/h1-16,18,20,36-37H,17,19H2 RLNNMCHGUCZOSK-UHFFFAOYSA-N 50294739 CHEMBL549892::{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-(1H-indol-7-ylmethyl)amine Oxysterols receptor LXR-beta 38000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45271480 104136270 CHEMBL549892 ZINC43018333 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154494 FC(F)(F)c1ccc(Cl)cc1COc1cccc(c1)-c1c(Cc2ccccc2)nnc2c(cccc12)C(F)(F)F InChI=1S/C30H19ClF6N2O/c31-21-12-13-24(29(32,33)34)20(15-21)17-40-22-9-4-8-19(16-22)27-23-10-5-11-25(30(35,36)37)28(23)39-38-26(27)14-18-6-2-1-3-7-18/h1-13,15-16H,14,17H2 AILNGBDJCOOHHQ-UHFFFAOYSA-N 50294754 3-Benzyl-4-(3-{[5-chloro-2-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline::CHEMBL563706 Oxysterols receptor LXR-beta 57000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11853795 104136285 CHEMBL563706 ZINC43019134 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154497 FC(F)(F)c1cccc(CNc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1Cl InChI=1S/C29H20Cl2F3N3/c30-24-14-6-12-22-26(25(36-37-28(22)24)15-18-7-2-1-3-8-18)19-9-4-11-21(16-19)35-17-20-10-5-13-23(27(20)31)29(32,33)34/h1-14,16,35H,15,17H2 XHUGCOUNHPKMDJ-UHFFFAOYSA-N 50294743 CHEMBL550035::[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chloro-3-(trifluoromethyl)benzyl]amine Oxysterols receptor LXR-beta 3630 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11855620 104136274 CHEMBL550035 ZINC43010182 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154499 Fc1ccc(c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)c1)C(F)(F)F InChI=1S/C30H19F7N2O/c31-21-12-13-24(29(32,33)34)20(15-21)17-40-22-9-4-8-19(16-22)27-23-10-5-11-25(30(35,36)37)28(23)39-38-26(27)14-18-6-2-1-3-7-18/h1-13,15-16H,14,17H2 IKYMOODGQWULPF-UHFFFAOYSA-N 50294742 3-Benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline::CHEMBL550568 Oxysterols receptor LXR-beta 38000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11853793 104136273 CHEMBL550568 ZINC43123232 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154512 Fc1c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)cccc1C(F)(F)F InChI=1S/C30H19F7N2O/c31-27-20(10-5-13-23(27)29(32,33)34)17-40-21-11-4-9-19(16-21)26-22-12-6-14-24(30(35,36)37)28(22)39-38-25(26)15-18-7-2-1-3-8-18/h1-14,16H,15,17H2 CGTFWGIWVIWUQF-UHFFFAOYSA-N 50294755 3-Benzyl-4-(3-{[2-fluoro-3-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline::CHEMBL550441 Oxysterols receptor LXR-beta 63000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11853546 104136286 CHEMBL550441 ZINC43017051 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154514 Fc1ccc(c(CNc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1)C(F)(F)F InChI=1S/C29H20ClF4N3/c30-25-11-5-10-23-27(26(36-37-28(23)25)14-18-6-2-1-3-7-18)19-8-4-9-22(16-19)35-17-20-15-21(31)12-13-24(20)29(32,33)34/h1-13,15-16,35H,14,17H2 ITLFECPZLKVOJU-UHFFFAOYSA-N 50294751 CHEMBL551584::[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-fluoro-2-(trifluoromethyl)benzyl]amine Oxysterols receptor LXR-beta 62000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11855623 104136282 CHEMBL551584 ZINC43062107 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154520 Clc1ccccc1COc1cccc(c1)-c1c(Cc2ccccc2)nnc2c(Cl)cccc12 InChI=1S/C28H20Cl2N2O/c29-24-14-5-4-10-21(24)18-33-22-12-6-11-20(17-22)27-23-13-7-15-25(30)28(23)32-31-26(27)16-19-8-2-1-3-9-19/h1-15,17H,16,18H2 PGMONDSMQYHMDO-UHFFFAOYSA-N 50294746 3-Benzyl-8-chloro-4-{3-[(2-chlorobenzyl)oxy]phenyl}-cinnoline::CHEMBL549418 Oxysterols receptor LXR-beta 14000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854316 104136277 CHEMBL549418 ZINC36479671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154523 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154525 Cn1c(CNc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)cc2ccccc12 InChI=1S/C31H25ClN4/c1-36-25(19-22-11-5-6-16-29(22)36)20-33-24-13-7-12-23(18-24)30-26-14-8-15-27(32)31(26)35-34-28(30)17-21-9-3-2-4-10-21/h2-16,18-19,33H,17,20H2,1H3 VFJCBPIZXGHCID-UHFFFAOYSA-N 50294734 3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][(1-methyl-1H-indol-2-yl)methyl]amine::CHEMBL550847 Oxysterols receptor LXR-beta 24000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294734&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11855082 104136265 CHEMBL550847 ZINC36485908 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154530 Cc1c(C)c(NCc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)ccc1CC(O)=O InChI=1S/C34H29F3N2O2/c1-21-22(2)30(15-14-25(21)18-31(40)41)38-19-24-10-6-11-26(17-24)32-27(16-23-8-4-3-5-9-23)20-39-33-28(32)12-7-13-29(33)34(35,36)37/h3-15,17,20,38H,16,18-19H2,1-2H3,(H,40,41) GCAJNTSVNKDATQ-UHFFFAOYSA-N 50227159 2-(4-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)-2,3-dimethylphenyl)acetic acid::CHEMBL253521 Oxysterols receptor LXR-beta 4000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50227159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50227159&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25226691 104097345 CHEMBL253521 ZINC28978870 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154534 Clc1cccc2c(c(Cc3ccccc3)nnc12)-c1cccc(OCc2ccccc2)c1 InChI=1S/C28H21ClN2O/c29-25-16-8-15-24-27(26(30-31-28(24)25)17-20-9-3-1-4-10-20)22-13-7-14-23(18-22)32-19-21-11-5-2-6-12-21/h1-16,18H,17,19H2 WLJAORRKUJBIBV-UHFFFAOYSA-N 50294745 3-Benzyl-4-[3-(benzyloxy)phenyl]-8-chlorocinnoline::CHEMBL552157 Oxysterols receptor LXR-beta 46000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854573 104136276 CHEMBL552157 ZINC36479967 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154535 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 9000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154537 Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(cccc34)C(F)(F)F)c12 InChI=1S/C32H24F3N3O/c1-38-17-16-22-10-5-12-24(31(22)38)20-39-25-13-6-11-23(19-25)29-26-14-7-15-27(32(33,34)35)30(26)37-36-28(29)18-21-8-3-2-4-9-21/h2-17,19H,18,20H2,1H3 QJFZBMOXZHRSFQ-UHFFFAOYSA-N 50294740 3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-phenyl}-8-(trifluoromethyl)cinnoline::CHEMBL554508 Oxysterols receptor LXR-beta 1160 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11856960 104136271 CHEMBL554508 ZINC36488241 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154538 FC(F)(F)c1ccc(Cl)cc1COc1cccc(c1)-c1c(nnc2c(Cl)cccc12)-c1ccccc1 InChI=1S/C28H17Cl2F3N2O/c29-20-12-13-23(28(31,32)33)19(14-20)16-36-21-9-4-8-18(15-21)25-22-10-5-11-24(30)27(22)35-34-26(25)17-6-2-1-3-7-17/h1-15H,16H2 YRKKEBHUBAIMEB-UHFFFAOYSA-N 50294752 8-Chloro-4-(3-{[5-chloro-2-(trifluoromethyl)benzyl]oxy}-phenyl)-3-phenylcinnoline::CHEMBL557702 Oxysterols receptor LXR-beta 65000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45273240 104136283 CHEMBL557702 ZINC42989726 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154539 FC(F)(F)c1cccc(CNc2cccc(c2)-c2c(nnc3c(Cl)cccc23)-c2ccccc2)c1Cl InChI=1S/C28H18Cl2F3N3/c29-23-14-6-12-21-24(26(35-36-27(21)23)17-7-2-1-3-8-17)18-9-4-11-20(15-18)34-16-19-10-5-13-22(25(19)30)28(31,32)33/h1-15,34H,16H2 JIFCPICGKDCWFQ-UHFFFAOYSA-N 50294753 CHEMBL552518::[3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][2-chloro-3-(trifluoromethyl)benzyl]amine Oxysterols receptor LXR-beta 19000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11855894 104136284 CHEMBL552518 ZINC43066680 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154540 Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(cccc34)C(F)(F)F)c12 InChI=1S/C32H24F3N3O/c1-38-17-16-22-10-5-12-24(31(22)38)20-39-25-13-6-11-23(19-25)29-26-14-7-15-27(32(33,34)35)30(26)37-36-28(29)18-21-8-3-2-4-9-21/h2-17,19H,18,20H2,1H3 QJFZBMOXZHRSFQ-UHFFFAOYSA-N 50294740 3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-phenyl}-8-(trifluoromethyl)cinnoline::CHEMBL554508 Oxysterols receptor LXR-beta 14000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11856960 104136271 CHEMBL554508 ZINC36488241 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154542 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta 90 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154544 Cn1c(CNc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)cc2ccccc12 InChI=1S/C31H25ClN4/c1-36-25(19-22-11-5-6-16-29(22)36)20-33-24-13-7-12-23(18-24)30-26-14-8-15-27(32)31(26)35-34-28(30)17-21-9-3-2-4-10-21/h2-16,18-19,33H,17,20H2,1H3 VFJCBPIZXGHCID-UHFFFAOYSA-N 50294734 3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][(1-methyl-1H-indol-2-yl)methyl]amine::CHEMBL550847 Oxysterols receptor LXR-beta 2780 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294734&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11855082 104136265 CHEMBL550847 ZINC36485908 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154545 Cn1c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)cc2ccccc12 InChI=1S/C32H24F3N3O/c1-38-24(18-22-11-5-6-16-29(22)38)20-39-25-13-7-12-23(19-25)30-26-14-8-15-27(32(33,34)35)31(26)37-36-28(30)17-21-9-3-2-4-10-21/h2-16,18-19H,17,20H2,1H3 IOWZLHRNMKWCPX-UHFFFAOYSA-N 50294756 3-Benzyl-4-{3-[(1-methyl-1H-indol-2-yl)methoxy]-phenyl}-8-(trifluoromethyl)cinnoline::CHEMBL561450 Oxysterols receptor LXR-beta 42000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11857214 104136287 CHEMBL561450 ZINC36488410 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154546 FC(F)(F)c1cccc(CNc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1Cl InChI=1S/C29H20Cl2F3N3/c30-24-14-6-12-22-26(25(36-37-28(22)24)15-18-7-2-1-3-8-18)19-9-4-11-21(16-19)35-17-20-10-5-13-23(27(20)31)29(32,33)34/h1-14,16,35H,15,17H2 XHUGCOUNHPKMDJ-UHFFFAOYSA-N 50294743 CHEMBL550035::[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chloro-3-(trifluoromethyl)benzyl]amine Oxysterols receptor LXR-beta 40000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11855620 104136274 CHEMBL550035 ZINC43010182 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154547 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 178 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154548 FC(F)(F)c1cccc(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)c1Cl InChI=1S/C30H19ClF6N2O/c31-27-20(10-5-13-23(27)29(32,33)34)17-40-21-11-4-9-19(16-21)26-22-12-6-14-24(30(35,36)37)28(22)39-38-25(26)15-18-7-2-1-3-8-18/h1-14,16H,15,17H2 ORZUZXZETYSZTE-UHFFFAOYSA-N 50294741 3-Benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline::CHEMBL561449 Oxysterols receptor LXR-beta 8600 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11853545 104136272 CHEMBL561449 ZINC43075250 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154550 FC(F)(F)c1cccc(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1Cl InChI=1S/C29H19Cl2F3N2O/c30-24-14-6-12-22-26(25(35-36-28(22)24)15-18-7-2-1-3-8-18)19-9-4-11-21(16-19)37-17-20-10-5-13-23(27(20)31)29(32,33)34/h1-14,16H,15,17H2 ZTRCQAWKQLDVDC-UHFFFAOYSA-N 50294744 3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)-benzyl]oxy}phenyl)cinnoline::CHEMBL550983 Oxysterols receptor LXR-beta 6540 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854570 104136275 CHEMBL550983 ZINC43021609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154551 FC(F)(F)c1ccc(Cl)cc1COc1cccc(c1)-c1c(Cc2ccccc2)nnc2c(Cl)cccc12 InChI=1S/C29H19Cl2F3N2O/c30-21-12-13-24(29(32,33)34)20(15-21)17-37-22-9-4-8-19(16-22)27-23-10-5-11-25(31)28(23)36-35-26(27)14-18-6-2-1-3-7-18/h1-13,15-16H,14,17H2 RJNWBBKBWBZHPH-UHFFFAOYSA-N 50294749 3-Benzyl-8-chloro-4-(3-{[5-chloro-2-(trifluoromethyl)-benzyl]oxy}phenyl)cinnoline::CHEMBL560648 Oxysterols receptor LXR-beta 85000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294749&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854572 104136280 CHEMBL560648 ZINC43122237 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154553 Cn1ccc2cccc(CNc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)c12 InChI=1S/C33H26F3N3/c1-39-17-16-23-10-5-12-25(32(23)39)20-37-27-13-6-11-24(19-27)30-26(18-22-8-3-2-4-9-22)21-38-31-28(30)14-7-15-29(31)33(34,35)36/h2-17,19,21,37H,18,20H2,1H3 IDEFAXMSWQNUAX-UHFFFAOYSA-N 50294736 CHEMBL558496::{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-[(1-methyl-1H-indol-7-yl)methyl]amine Oxysterols receptor LXR-beta 4170 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45273258 104136267 CHEMBL558496 ZINC43059595 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154554 FC(F)(F)c1cccc(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(cccc23)C(F)(F)F)c1Cl InChI=1S/C30H19ClF6N2O/c31-27-20(10-5-13-23(27)29(32,33)34)17-40-21-11-4-9-19(16-21)26-22-12-6-14-24(30(35,36)37)28(22)39-38-25(26)15-18-7-2-1-3-8-18/h1-14,16H,15,17H2 ORZUZXZETYSZTE-UHFFFAOYSA-N 50294741 3-Benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline::CHEMBL561449 Oxysterols receptor LXR-beta 43000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11853545 104136272 CHEMBL561449 ZINC43075250 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154555 Cn1ccc2cccc(COc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)c12 InChI=1S/C33H25F3N2O/c1-38-17-16-23-10-5-12-25(32(23)38)21-39-27-13-6-11-24(19-27)30-26(18-22-8-3-2-4-9-22)20-37-31-28(30)14-7-15-29(31)33(34,35)36/h2-17,19-20H,18,21H2,1H3 ZBNWVQXJYIJWEI-UHFFFAOYSA-N 50294737 3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-phenyl}-8-(trifluoromethyl)quinoline::CHEMBL551248 Oxysterols receptor LXR-beta 20000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45270660 104136268 CHEMBL551248 ZINC43022278 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154556 Cn1c(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc2ccccc12 InChI=1S/C33H26F3N3/c1-39-27(19-23-11-5-6-16-30(23)39)21-37-26-13-7-12-24(18-26)31-25(17-22-9-3-2-4-10-22)20-38-32-28(31)14-8-15-29(32)33(34,35)36/h2-16,18-20,37H,17,21H2,1H3 MJGWHEJLSWUCNL-UHFFFAOYSA-N 50294738 CHEMBL551981::{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-[(1-methyl-1H-indol-2-yl)methyl]amine Oxysterols receptor LXR-beta 10180 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45272392 104136269 CHEMBL551981 ZINC43021150 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154558 Cn1ccc2cccc(CNc3cccc(c3)-c3c(Cc4ccccc4)nnc4c(Cl)cccc34)c12 InChI=1S/C31H25ClN4/c1-36-17-16-22-10-5-12-24(31(22)36)20-33-25-13-6-11-23(19-25)29-26-14-7-15-27(32)30(26)35-34-28(29)18-21-8-3-2-4-9-21/h2-17,19,33H,18,20H2,1H3 RXAWOIWCWMZXHF-UHFFFAOYSA-N 50294733 CHEMBL558494::N-[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]-N-[(1-methyl-1H-indol-7-yl)methyl]amine Oxysterols receptor LXR-beta 24000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294733&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11854313 104136264 CHEMBL558494 ZINC36479669 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154560 FC(F)(F)c1ccc(Cl)c(COc2cccc(c2)-c2c(Cc3ccccc3)nnc3c(Cl)cccc23)c1 InChI=1S/C29H19Cl2F3N2O/c30-24-13-12-21(29(32,33)34)15-20(24)17-37-22-9-4-8-19(16-22)27-23-10-5-11-25(31)28(23)36-35-26(27)14-18-6-2-1-3-7-18/h1-13,15-16H,14,17H2 NZQXAMQFVOUGNZ-UHFFFAOYSA-N 50294748 3-Benzyl-8-chloro-4-(3-{[2-chloro-5-(trifluoromethyl)-benzyl]oxy}phenyl)cinnoline::CHEMBL554698 Oxysterols receptor LXR-beta 12000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294748&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11857210 104136279 CHEMBL554698 ZINC43015078 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154561 Cn1ccc2cccc(CNc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)c12 InChI=1S/C33H26F3N3/c1-39-17-16-23-10-5-12-25(32(23)39)20-37-27-13-6-11-24(19-27)30-26(18-22-8-3-2-4-9-22)21-38-31-28(30)14-7-15-29(31)33(34,35)36/h2-17,19,21,37H,18,20H2,1H3 IDEFAXMSWQNUAX-UHFFFAOYSA-N 50294736 CHEMBL558496::{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-[(1-methyl-1H-indol-7-yl)methyl]amine Oxysterols receptor LXR-beta 34000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45273258 104136267 CHEMBL558496 ZINC43059595 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50154562 Cn1ccc2cccc(CNc3cccc(c3)-c3c(nnc4c(Cl)cccc34)-c3ccccc3)c12 InChI=1S/C30H23ClN4/c1-35-17-16-21-10-5-12-23(30(21)35)19-32-24-13-6-11-22(18-24)27-25-14-7-15-26(31)29(25)34-33-28(27)20-8-3-2-4-9-20/h2-18,32H,19H2,1H3 DFDLNHGSXIIXAJ-UHFFFAOYSA-N 50294735 CHEMBL558495::[3-(8-Chloro-3-phenylcinnolin-4-yl)phenyl][(1-methyl-1H-indol-7-yl)methyl]amine Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.bmc.2009.04.012 10.7270/Q2T72HH5 19394832 Hu, B; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wihelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11855081 104136266 CHEMBL558495 ZINC36485906 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155810 COc1ccc(CCc2cccc(c2)N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H21NO4/c1-28-21-13-12-17(15-22(21)29-2)11-10-16-6-5-7-18(14-16)25-23(26)19-8-3-4-9-20(19)24(25)27/h3-9,12-15H,10-11H2,1-2H3 SRSGBGGAMXGBMK-UHFFFAOYSA-N 50298703 CHEMBL572488::N-{3-[2-(3,4-Dimethoxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298703&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481854 104140232 CHEMBL572488 ZINC45284335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155814 O=C1N(C(=O)c2ccccc12)c1cccc(CCc2ccccc2)c1 InChI=1S/C22H17NO2/c24-21-19-11-4-5-12-20(19)22(25)23(21)18-10-6-9-17(15-18)14-13-16-7-2-1-3-8-16/h1-12,15H,13-14H2 DJMIPAXALMXBNX-UHFFFAOYSA-N 50298702 CHEMBL575661::N-[3-(2-Phenylethyl)phenyl]phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481853 104140231 CHEMBL575661 ZINC45299971 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155817 Oc1cccc(CCc2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)c1 InChI=1S/C22H13Cl4NO3/c23-17-15-16(18(24)20(26)19(17)25)22(30)27(21(15)29)13-8-6-11(7-9-13)4-5-12-2-1-3-14(28)10-12/h1-3,6-10,28H,4-5H2 JWIJBMTZBIEELR-UHFFFAOYSA-N 50298675 4,5,6,7-Tetrachloro-N-{4-[2-(3-hydroxyphenyl)ethyl]phenyl}phthalimide::CHEMBL572477 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298675&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481813 104140204 CHEMBL572477 ZINC45283351 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155818 COc1cccc(CCc2ccc(cc2)N2C(=O)c3ccccc3C2=O)c1 InChI=1S/C23H19NO3/c1-27-19-6-4-5-17(15-19)10-9-16-11-13-18(14-12-16)24-22(25)20-7-2-3-8-21(20)23(24)26/h2-8,11-15H,9-10H2,1H3 CNZNMDJWLSHLJZ-UHFFFAOYSA-N 50298669 CHEMBL572484::N-{4-[2-(3-Methoxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta 3500 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298669&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481844 104140198 CHEMBL572484 ZINC45283697 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155820 Oc1ccc(CCc2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1O InChI=1S/C22H13Cl4NO4/c23-17-15-16(18(24)20(26)19(17)25)22(31)27(21(15)30)12-6-3-10(4-7-12)1-2-11-5-8-13(28)14(29)9-11/h3-9,28-29H,1-2H2 MSMQHCNIVJOKRR-UHFFFAOYSA-N 50298677 4,5,6,7-Tetrachloro-N-{4-[2-(3,4-dihydroxyphenyl)ethyl]phenyl}phthalimide::CHEMBL575000 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298677&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481812 104140206 CHEMBL575000 ZINC45298469 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155821 Oc1ccc(\C=C\c2ccc(cc2)N2C(=O)c3ccccc3C2=O)cc1O InChI=1S/C22H15NO4/c24-19-12-9-15(13-20(19)25)6-5-14-7-10-16(11-8-14)23-21(26)17-3-1-2-4-18(17)22(23)27/h1-13,24-25H/b6-5+ ZPSXLDRGOUALHZ-AATRIKPKSA-N 50298695 CHEMBL575439::N-{4-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]phenyl}phthalimide Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298695&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481843 104140224 CHEMBL575439 ZINC45299228 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155824 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccc(\C=C\c2ccccc2)cc1 InChI=1S/C22H11Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-10-8-13(9-11-14)7-6-12-4-2-1-3-5-12/h1-11H/b7-6+ ACXQAYBUGCBSSN-VOTSOKGWSA-N 50298693 4,5,6,7-Tetrachloro-N-{4-[(1E)-2-phenylethenyl]phenyl}phthalimide::CHEMBL577607 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298693&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481836 104140222 CHEMBL577607 ZINC45289850 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155826 Oc1ccc(CCc2cccc(c2)N2C(=O)c3ccccc3C2=O)cc1O InChI=1S/C22H17NO4/c24-19-11-10-15(13-20(19)25)9-8-14-4-3-5-16(12-14)23-21(26)17-6-1-2-7-18(17)22(23)27/h1-7,10-13,24-25H,8-9H2 RQVFGVOHYJNEGD-UHFFFAOYSA-N 50298699 CHEMBL575664::N-{3-[2-(3,4-Dihydroxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta 7600 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298699&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481861 104140228 CHEMBL575664 ZINC45300244 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155827 Oc1ccc(CCc2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1 InChI=1S/C22H13Cl4NO3/c23-17-15-16(18(24)20(26)19(17)25)22(30)27(21(15)29)13-3-1-2-12(10-13)5-4-11-6-8-14(28)9-7-11/h1-3,6-10,28H,4-5H2 TYJQTSNBDAHITD-UHFFFAOYSA-N 50298671 4,5,6,7-Tetrachloro-N-{3-[2-(4-hydroxyphenyl)ethyl]phenyl}phthalimide::CHEMBL577573 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298671&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481838 104140200 CHEMBL577573 ZINC45290991 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155828 Oc1ccc(CCc2ccc(cc2)N2C(=O)c3ccccc3C2=O)cc1O InChI=1S/C22H17NO4/c24-19-12-9-15(13-20(19)25)6-5-14-7-10-16(11-8-14)23-21(26)17-3-1-2-4-18(17)22(23)27/h1-4,7-13,24-25H,5-6H2 RZUPIZSDKRTTHJ-UHFFFAOYSA-N 50298696 CHEMBL574086::N-{4-[2-(3,4-Dihydroxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >3000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298696&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481824 104140225 CHEMBL574086 ZINC45284466 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155830 COc1ccc(CCc2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1OC InChI=1S/C24H17Cl4NO4/c1-32-15-9-8-13(11-16(15)33-2)7-6-12-4-3-5-14(10-12)29-23(30)17-18(24(29)31)20(26)22(28)21(27)19(17)25/h3-5,8-11H,6-7H2,1-2H3 YQHDDDLAABOHBB-UHFFFAOYSA-N 50298688 4,5,6,7-Tetrachloro-N-{3-[2-(3,4-dimethoxyphenyl)ethyl]phenyl}phthalimide::CHEMBL573648 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298688&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481846 104140217 CHEMBL573648 ZINC49695188 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155832 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1cccc(CCc2ccccc2)c1 InChI=1S/C22H13Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-8-4-7-13(11-14)10-9-12-5-2-1-3-6-12/h1-8,11H,9-10H2 YDTATDXEIIVAQM-UHFFFAOYSA-N 50298687 4,5,6,7-Tetrachloro-N-[3-(2-phenylethyl)phenyl]phthalimide::CHEMBL576924 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298687&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481845 104140216 CHEMBL576924 ZINC45300618 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155834 COc1ccc(\C=C\c2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1OC InChI=1S/C24H15Cl4NO4/c1-32-15-9-8-13(11-16(15)33-2)7-6-12-4-3-5-14(10-12)29-23(30)17-18(24(29)31)20(26)22(28)21(27)19(17)25/h3-11H,1-2H3/b7-6+ ACLOSINMMSLCHB-VOTSOKGWSA-N 50298692 4,5,6,7-Tetrachloro-N-{3-[(1E)-2-(3,4-dimethoxyphenyl)ethenyl]phenyl}phthalimide::CHEMBL574311 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298692&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481826 104140221 CHEMBL574311 ZINC49695576 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155836 COc1cccc(CCc2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)c1 InChI=1S/C23H15Cl4NO3/c1-31-15-4-2-3-13(11-15)6-5-12-7-9-14(10-8-12)28-22(29)16-17(23(28)30)19(25)21(27)20(26)18(16)24/h2-4,7-11H,5-6H2,1H3 NZFZSSRHOHMVFN-UHFFFAOYSA-N 50298674 4,5,6,7-Tetrachloro-N-{4-[2-(3-methoxyphenyl)ethyl]phenyl}phthalimide::CHEMBL575008 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298674&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481851 104140203 CHEMBL575008 ZINC45299598 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155837 Oc1ccc(CCc2ccccc2N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1O InChI=1S/C22H13Cl4NO4/c23-17-15-16(18(24)20(26)19(17)25)22(31)27(21(15)30)12-4-2-1-3-11(12)7-5-10-6-8-13(28)14(29)9-10/h1-4,6,8-9,28-29H,5,7H2 NUIRGDYSUOJTOH-UHFFFAOYSA-N 50298685 4,5,6,7-Tetrachloro-N-{2-[2-(3,4-dihydroxyphenyl)ethyl]phenyl}phthalimide::CHEMBL575001 Oxysterols receptor LXR-beta 17000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298685&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481837 104140214 CHEMBL575001 ZINC45298758 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155838 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1CCc1ccccc1 InChI=1S/C22H13Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-9-5-4-8-13(14)11-10-12-6-2-1-3-7-12/h1-9H,10-11H2 FKRZWNNFTCLNFL-UHFFFAOYSA-N 50298686 4,5,6,7-Tetrachloro-N-[2-(2-phenylethyl)phenyl]phthalimide::CHEMBL574310 Oxysterols receptor LXR-beta >3000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298686&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481825 104140215 CHEMBL574310 ZINC45284857 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155839 COc1ccc(\C=C\c2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1OC InChI=1S/C24H15Cl4NO4/c1-32-15-10-7-13(11-16(15)33-2)4-3-12-5-8-14(9-6-12)29-23(30)17-18(24(29)31)20(26)22(28)21(27)19(17)25/h3-11H,1-2H3/b4-3+ RDPYBBXRFUBMME-ONEGZZNKSA-N 50298684 4,5,6,7-Tetrachloro-N-{4-[(1E)-2-(3,4-dimethoxyphenyl)ethenyl]phenyl}phthalimide::CHEMBL573649 Oxysterols receptor LXR-beta 14000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298684&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481847 104140213 CHEMBL573649 ZINC49695189 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155840 Oc1ccc(CCc2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1O InChI=1S/C22H13Cl4NO4/c23-17-15-16(18(24)20(26)19(17)25)22(31)27(21(15)30)12-3-1-2-10(8-12)4-5-11-6-7-13(28)14(29)9-11/h1-3,6-9,28-29H,4-5H2 SYQXCJLRSLJMRQ-UHFFFAOYSA-N 50298680 4,5,6,7-Tetrachloro-N-{3-[2-(3,4-dihydroxyphenyl)ethyl]phenyl}phthalimide::CHEMBL575007 Oxysterols receptor LXR-beta 21000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298680&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481850 104140209 CHEMBL575007 ZINC45299596 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155842 Oc1ccc(CCc2ccccc2N2C(=O)c3ccccc3C2=O)cc1O InChI=1S/C22H17NO4/c24-19-12-10-14(13-20(19)25)9-11-15-5-1-4-8-18(15)23-21(26)16-6-2-3-7-17(16)22(23)27/h1-8,10,12-13,24-25H,9,11H2 ZHKKNZUQHSYYIA-UHFFFAOYSA-N 50298701 CHEMBL577802::N-{2-[2-(3,4-Dihydroxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298701&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481849 104140230 CHEMBL577802 ZINC45289866 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155843 Oc1ccc(\C=C\c2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1O InChI=1S/C22H11Cl4NO4/c23-17-15-16(18(24)20(26)19(17)25)22(31)27(21(15)30)12-6-3-10(4-7-12)1-2-11-5-8-13(28)14(29)9-11/h1-9,28-29H/b2-1+ TXVRGWLYTBYDLP-OWOJBTEDSA-N 50298672 4,5,6,7-Tetrachloro-N-{4-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]phenyl}phthalimide::CHEMBL574342 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298672&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481859 104140201 CHEMBL574342 ZINC45262031 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155844 COc1ccc(CCc2ccccc2N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H21NO4/c1-28-21-14-12-16(15-22(21)29-2)11-13-17-7-3-6-10-20(17)25-23(26)18-8-4-5-9-19(18)24(25)27/h3-10,12,14-15H,11,13H2,1-2H3 GPIKIQYFADSPRZ-UHFFFAOYSA-N 50298700 CHEMBL574787::N-{2-[2-(3,4-Dimethoxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298700&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481848 104140229 CHEMBL574787 ZINC45288016 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155847 COc1ccc(\C=C\c2ccc(cc2)N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H19NO4/c1-28-21-14-11-17(15-22(21)29-2)8-7-16-9-12-18(13-10-16)25-23(26)19-5-3-4-6-20(19)24(25)27/h3-15H,1-2H3/b8-7+ LJGBVEUBOGDWBB-BQYQJAHWSA-N 50298697 CHEMBL572706::N-{4-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481832 104140226 CHEMBL572706 ZINC45288157 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155848 COc1ccc(CCc2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1 InChI=1S/C23H15Cl4NO3/c1-31-15-9-7-12(8-10-15)5-6-13-3-2-4-14(11-13)28-22(29)16-17(23(28)30)19(25)21(27)20(26)18(16)24/h2-4,7-11H,5-6H2,1H3 XXNGDPQKHJDHDN-UHFFFAOYSA-N 50298678 4,5,6,7-Tetrachloro-N-{3-[2-(4-methoxyphenyl)ethyl]phenyl}phthalimide::CHEMBL573399 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298678&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481833 104140207 CHEMBL573399 ZINC45286694 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155855 COc1ccc(CCc2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1 InChI=1S/C23H15Cl4NO3/c1-31-15-10-6-13(7-11-15)3-2-12-4-8-14(9-5-12)28-22(29)16-17(23(28)30)19(25)21(27)20(26)18(16)24/h4-11H,2-3H2,1H3 UQMCVDAPRKWQME-UHFFFAOYSA-N 50298683 4,5,6,7-Tetrachloro-N-{4-[2-(4-methoxyphenyl)ethyl]phenyl}phthalimide::CHEMBL574082 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298683&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481822 104140212 CHEMBL574082 ZINC45284148 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155856 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1cccc(\C=C\c2ccccc2)c1 InChI=1S/C22H11Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-8-4-7-13(11-14)10-9-12-5-2-1-3-6-12/h1-11H/b10-9+ UQPGKXDGPCMIOX-MDZDMXLPSA-N 50298691 4,5,6,7-Tetrachloro-N-{3-[(1E)-2-phenylethenyl]phenyl}phthalimide::CHEMBL574070 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298691&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481814 104140220 CHEMBL574070 ZINC45261952 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155863 Oc1cccc(CCc2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)c1 InChI=1S/C22H13Cl4NO3/c23-17-15-16(18(24)20(26)19(17)25)22(30)27(21(15)29)13-5-1-3-11(9-13)7-8-12-4-2-6-14(28)10-12/h1-6,9-10,28H,7-8H2 CWOZAVNAEIIMQN-UHFFFAOYSA-N 50298670 4,5,6,7-Tetrachloro-N-{3-[2-(3-hydroxyphenyl)ethyl]phenyl}phthalimide::CHEMBL573383 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298670&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481827 104140199 CHEMBL573383 ZINC45285138 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155945 Oc1ccc(CCc2ccc(cc2)N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C22H17NO3/c24-18-13-9-16(10-14-18)6-5-15-7-11-17(12-8-15)23-21(25)19-3-1-2-4-20(19)22(23)26/h1-4,7-14,24H,5-6H2 OFQPQJJVXCUPFR-UHFFFAOYSA-N 50298673 CHEMBL575857::N-{4-[2-(4-Hydroxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298673&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481821 104140202 CHEMBL575857 ZINC45299997 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155946 O=C1N(C(=O)c2ccccc12)c1ccccc1CCc1ccccc1 InChI=1S/C22H17NO2/c24-21-18-11-5-6-12-19(18)22(25)23(21)20-13-7-4-10-17(20)15-14-16-8-2-1-3-9-16/h1-13H,14-15H2 XGSWAPNRKGOSKD-UHFFFAOYSA-N 23840 2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindole-1,3-dione::CHEMBL246144::PP2P Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23840&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10616182 50092092 CHEMBL246144 ZINC28898291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155947 COc1ccc(CCc2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1OC InChI=1S/C24H17Cl4NO4/c1-32-15-10-7-13(11-16(15)33-2)4-3-12-5-8-14(9-6-12)29-23(30)17-18(24(29)31)20(26)22(28)21(27)19(17)25/h5-11H,3-4H2,1-2H3 LTQWLFFFMURTIT-UHFFFAOYSA-N 50298690 4,5,6,7-Tetrachloro-N-{4-[2-(3,4-dimethoxyphenyl)ethyl]phenyl}phthalimide::CHEMBL574341 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298690&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481858 104140219 CHEMBL574341 ZINC49708987 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155948 Oc1ccc(CCc2ccc(cc2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1 InChI=1S/C22H13Cl4NO3/c23-17-15-16(18(24)20(26)19(17)25)22(30)27(21(15)29)13-7-3-11(4-8-13)1-2-12-5-9-14(28)10-6-12/h3-10,28H,1-2H2 PGZFUFYKPUNVFR-UHFFFAOYSA-N 50298694 4,5,6,7-Tetrachloro-N-{4-[2-(4-hydroxyphenyl)ethyl]phenyl}phthalimide::CHEMBL577580 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481823 104140223 CHEMBL577580 ZINC45289330 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155949 COc1cccc(CCc2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)c1 InChI=1S/C23H15Cl4NO3/c1-31-15-7-3-5-13(11-15)9-8-12-4-2-6-14(10-12)28-22(29)16-17(23(28)30)19(25)21(27)20(26)18(16)24/h2-7,10-11H,8-9H2,1H3 LPRDFXAERLBTQG-UHFFFAOYSA-N 50298676 4,5,6,7-Tetrachloro-N-{3-[2-(3-methoxyphenyl)ethyl]phenyl}phthalimide::CHEMBL577578 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298676&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481815 104140205 CHEMBL577578 ZINC45288877 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155950 O=C1N(C(=O)c2ccccc12)c1ccc(CCc2ccccc2)cc1 InChI=1S/C22H17NO2/c24-21-19-8-4-5-9-20(19)22(25)23(21)18-14-12-17(13-15-18)11-10-16-6-2-1-3-7-16/h1-9,12-15H,10-11H2 AXTFYGWMYSVZKF-UHFFFAOYSA-N 50298704 CHEMBL585552::N-(4-(2-Phenylethyl)phenyl)phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298704&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481819 104140233 CHEMBL585552 ZINC45322531 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155951 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccc(CCc2ccccc2)cc1 InChI=1S/C22H13Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-10-8-13(9-11-14)7-6-12-4-2-1-3-5-12/h1-5,8-11H,6-7H2 JTLNPSPMAIAAEY-UHFFFAOYSA-N 50298689 4,5,6,7-Tetrachloro-N-[4-(2-phenylethyl)phenyl]phthalimide::CHEMBL576137 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298689&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481855 104140218 CHEMBL576137 ZINC45300840 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155952 Oc1cccc(CCc2ccc(cc2)N2C(=O)c3ccccc3C2=O)c1 InChI=1S/C22H17NO3/c24-18-5-3-4-16(14-18)9-8-15-10-12-17(13-11-15)23-21(25)19-6-1-2-7-20(19)22(23)26/h1-7,10-14,24H,8-9H2 TUMZBTITCWKZAT-UHFFFAOYSA-N 50298682 CHEMBL574107::N-{4-[2-(3-Hydroxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298682&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481863 104140211 CHEMBL574107 ZINC45284468 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155953 Oc1ccc(\C=C\c2cccc(c2)N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1O InChI=1S/C22H11Cl4NO4/c23-17-15-16(18(24)20(26)19(17)25)22(31)27(21(15)30)12-3-1-2-10(8-12)4-5-11-6-7-13(28)14(29)9-11/h1-9,28-29H/b5-4+ WZEUOZFLJDPKMG-SNAWJCMRSA-N 50298681 4,5,6,7-Tetrachloro-N-{3-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]phenyl}phthalimide::4.1.25. 4,5,6,7-Tetrachloro-N-{3-[(1E)-2-(3,4-dihydroxyphenyl)ethenyl]phenyl}phthalimide::CHEMBL577149 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298681&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44537910 104140210 CHEMBL577149 ZINC45290161 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155954 COc1ccc(CCc2ccc(cc2)N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C23H19NO3/c1-27-19-14-10-17(11-15-19)7-6-16-8-12-18(13-9-16)24-22(25)20-4-2-3-5-21(20)23(24)26/h2-5,8-15H,6-7H2,1H3 CRWGIKAUSJNKIC-UHFFFAOYSA-N 50298668 CHEMBL575856::N-{4-[2-(4-Methoxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298668&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44537911 104140197 CHEMBL575856 ZINC45299995 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155955 COc1ccc(CCc2ccccc2N2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1OC InChI=1S/C24H17Cl4NO4/c1-32-15-10-8-12(11-16(15)33-2)7-9-13-5-3-4-6-14(13)29-23(30)17-18(24(29)31)20(26)22(28)21(27)19(17)25/h3-6,8,10-11H,7,9H2,1-2H3 UROSCDVZSHWIDU-UHFFFAOYSA-N 50298679 4,5,6,7-Tetrachloro-N-{2-[2-(3, 4-dimethoxyphenyl)ethyl]phenyl}phthalimide::4,5,6,7-Tetrachloro-N-{2-[2-(3,4-dimethoxyphenyl)ethyl]phenyl}phthalimide::CHEMBL574298 Oxysterols receptor LXR-beta 7700 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298679&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481835 104140208 CHEMBL574298 ZINC49709531 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155956 O=C1N(C(=O)c2ccccc12)c1ccc(\C=C\c2ccccc2)cc1 InChI=1S/C22H15NO2/c24-21-19-8-4-5-9-20(19)22(25)23(21)18-14-12-17(13-15-18)11-10-16-6-2-1-3-7-16/h1-15H/b11-10+ NTDZLFGRAUKENS-ZHACJKMWSA-N 50298705 CHEMBL573382::N-{4-[(1E)-2-Phenylethenyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298705&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 680534 104140234 CHEMBL573382 ZINC00045144 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50155957 COc1ccc(CCc2ccc(cc2)N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H21NO4/c1-28-21-14-11-17(15-22(21)29-2)8-7-16-9-12-18(13-10-16)25-23(26)19-5-3-4-6-20(19)24(25)27/h3-6,9-15H,7-8H2,1-2H3 OYXKKTJMBBRJMX-UHFFFAOYSA-N 50298698 CHEMBL577605::N-{4-[2-(3,4-Dimethoxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta 4300 ChEMBL 10.1016/j.bmc.2009.05.066 10.7270/Q2B56JSN 19539483 Motoshima, K; Noguchi-Yachide, T; Sugita, K; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298698&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481820 104140227 CHEMBL577605 ZINC45289333 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151872 C[C@H](CC[C@@H]1OC1(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H44O2/c1-17(6-11-24-25(2,3)29-24)21-9-10-22-20-8-7-18-16-19(28)12-14-26(18,4)23(20)13-15-27(21,22)5/h7,17,19-24,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,24+,26+,27-/m1/s1 OSENKJZWYQXHBN-XVYZBDJZSA-N 20164 (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-dimethyloxiran-2-yl]butan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::24(S),25-epoxycholesterol::CHEMBL434302::Epoxycholesterol Oxysterols receptor LXR-beta 286 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20164&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search CO1 6XBM,1P8D,6OT0 3247059 49688239 CHEMBL434302 2751 C15632 ZINC06201930 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151873 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 8 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151874 CN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(cc1)C#N InChI=1S/C18H15ClF3N3O4S/c1-17(27,18(20,21)22)16(26)24-15-8-5-12(9-14(15)19)25(2)30(28,29)13-6-3-11(10-23)4-7-13/h3-9,27H,1-2H3,(H,24,26) NZPSTYAGNIOCBZ-UHFFFAOYSA-N 50258121 CHEMBL495196::N-(2-chloro-4-(4-cyano-N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta 2700 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258121&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42601437 104108929 CHEMBL495196 ZINC40956660 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151875 COC(=O)c1ccc(cc1)S(=O)(=O)N(C)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1 InChI=1S/C19H18ClF3N2O6S/c1-18(28,19(21,22)23)17(27)24-15-9-6-12(10-14(15)20)25(2)32(29,30)13-7-4-11(5-8-13)16(26)31-3/h4-10,28H,1-3H3,(H,24,27) ULBJHVVCMCYIST-UHFFFAOYSA-N 50258122 CHEMBL495197::methyl 4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)benzoate Oxysterols receptor LXR-beta 3810 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258122&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573679 104108930 CHEMBL495197 ZINC40956666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151876 CN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(cc1)C#N InChI=1S/C18H15ClF3N3O4S/c1-17(27,18(20,21)22)16(26)24-15-8-5-12(9-14(15)19)25(2)30(28,29)13-6-3-11(10-23)4-7-13/h3-9,27H,1-2H3,(H,24,26) NZPSTYAGNIOCBZ-UHFFFAOYSA-N 50258121 CHEMBL495196::N-(2-chloro-4-(4-cyano-N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta 2600 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258121&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42601437 104108929 CHEMBL495196 ZINC40956660 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151877 COC(=O)c1ccc(cc1)S(=O)(=O)N(C)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1 InChI=1S/C19H18ClF3N2O6S/c1-18(28,19(21,22)23)17(27)24-15-9-6-12(10-14(15)20)25(2)32(29,30)13-7-4-11(5-8-13)16(26)31-3/h4-10,28H,1-3H3,(H,24,27) ULBJHVVCMCYIST-UHFFFAOYSA-N 50258122 CHEMBL495197::methyl 4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)benzoate Oxysterols receptor LXR-beta 2320 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258122&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573679 104108930 CHEMBL495197 ZINC40956666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151878 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 75 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151879 CN(c1ccc(NC(=O)[C@](C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccccc1 InChI=1S/C17H16ClF3N2O4S/c1-16(25,17(19,20)21)15(24)22-14-9-8-11(10-13(14)18)23(2)28(26,27)12-6-4-3-5-7-12/h3-10,25H,1-2H3,(H,22,24)/t16-/m0/s1 LRIXMTVCKAOMMS-INIZCTEOSA-N 50258030 (S)-N-(2-chloro-4-(N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide::CHEMBL492798 Oxysterols receptor LXR-beta 959 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573589 104108876 CHEMBL492798 ZINC40952259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151880 CN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(cc1)C(O)=O InChI=1S/C18H16ClF3N2O6S/c1-17(28,18(20,21)22)16(27)23-14-8-5-11(9-13(14)19)24(2)31(29,30)12-6-3-10(4-7-12)15(25)26/h3-9,28H,1-2H3,(H,23,27)(H,25,26) TZIIZUMIJNUKJX-UHFFFAOYSA-N 50258171 4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)benzoic acid::CHEMBL522668 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258171&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573717 104108960 CHEMBL522668 ZINC40957832 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151881 CN(c1ccc(NC(=O)[C@](C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccccc1 InChI=1S/C17H16ClF3N2O4S/c1-16(25,17(19,20)21)15(24)22-14-9-8-11(10-13(14)18)23(2)28(26,27)12-6-4-3-5-7-12/h3-10,25H,1-2H3,(H,22,24)/t16-/m0/s1 LRIXMTVCKAOMMS-INIZCTEOSA-N 50258030 (S)-N-(2-chloro-4-(N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide::CHEMBL492798 Oxysterols receptor LXR-beta 1900 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573589 104108876 CHEMBL492798 ZINC40952259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151882 CN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(cc1)C(O)=O InChI=1S/C18H16ClF3N2O6S/c1-17(28,18(20,21)22)16(27)23-14-8-5-11(9-13(14)19)24(2)31(29,30)12-6-3-10(4-7-12)15(25)26/h3-9,28H,1-2H3,(H,23,27)(H,25,26) TZIIZUMIJNUKJX-UHFFFAOYSA-N 50258171 4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)benzoic acid::CHEMBL522668 Oxysterols receptor LXR-beta >100000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258171&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573717 104108960 CHEMBL522668 ZINC40957832 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151883 COC(=O)CCc1ccc(cc1)S(=O)(=O)N(C)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1 InChI=1S/C21H22ClF3N2O6S/c1-20(30,21(23,24)25)19(29)26-17-10-7-14(12-16(17)22)27(2)34(31,32)15-8-4-13(5-9-15)6-11-18(28)33-3/h4-5,7-10,12,30H,6,11H2,1-3H3,(H,26,29) IWUARVFFASOWHD-UHFFFAOYSA-N 50258172 CHEMBL521811::methyl 3-(4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)phenyl)propanoate Oxysterols receptor LXR-beta 3500 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258172&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573718 104108961 CHEMBL521811 ZINC42891095 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151884 COC(=O)CCc1ccc(cc1)S(=O)(=O)N(C)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1 InChI=1S/C21H22ClF3N2O6S/c1-20(30,21(23,24)25)19(29)26-17-10-7-14(12-16(17)22)27(2)34(31,32)15-8-4-13(5-9-15)6-11-18(28)33-3/h4-5,7-10,12,30H,6,11H2,1-3H3,(H,26,29) IWUARVFFASOWHD-UHFFFAOYSA-N 50258172 CHEMBL521811::methyl 3-(4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)phenyl)propanoate Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258172&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573718 104108961 CHEMBL521811 ZINC42891095 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151887 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 78 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151888 CN(c1ccc(NC(=O)[C@](C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccccc1Cl InChI=1S/C17H15Cl2F3N2O4S/c1-16(26,17(20,21)22)15(25)23-13-8-7-10(9-12(13)19)24(2)29(27,28)14-6-4-3-5-11(14)18/h3-9,26H,1-2H3,(H,23,25)/t16-/m0/s1 FPFNQOKNVBGPTM-INIZCTEOSA-N 50258073 (S)-N-(2-chloro-4-(2-chloro-N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide::CHEMBL495173 Oxysterols receptor LXR-beta 813 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573631 104108902 CHEMBL495173 ZINC40953632 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151889 CN(c1ccc(NC(=O)[C@](C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(C)cc1 InChI=1S/C18H18ClF3N2O4S/c1-11-4-7-13(8-5-11)29(27,28)24(3)12-6-9-15(14(19)10-12)23-16(25)17(2,26)18(20,21)22/h4-10,26H,1-3H3,(H,23,25)/t17-/m0/s1 JLCBKZPEUMOYQE-KRWDZBQOSA-N 50258074 (S)-N-(2-chloro-4-(N,4-dimethylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide::CHEMBL521866 Oxysterols receptor LXR-beta 1590 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573632 104108903 CHEMBL521866 ZINC40953634 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151893 CN(c1ccc(NC(=O)[C@](C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccccc1Cl InChI=1S/C17H15Cl2F3N2O4S/c1-16(26,17(20,21)22)15(25)23-13-8-7-10(9-12(13)19)24(2)29(27,28)14-6-4-3-5-11(14)18/h3-9,26H,1-2H3,(H,23,25)/t16-/m0/s1 FPFNQOKNVBGPTM-INIZCTEOSA-N 50258073 (S)-N-(2-chloro-4-(2-chloro-N-methylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide::CHEMBL495173 Oxysterols receptor LXR-beta 626 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573631 104108902 CHEMBL495173 ZINC40953632 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151895 CN(c1ccc(NC(=O)[C@](C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(C)cc1 InChI=1S/C18H18ClF3N2O4S/c1-11-4-7-13(8-5-11)29(27,28)24(3)12-6-9-15(14(19)10-12)23-16(25)17(2,26)18(20,21)22/h4-10,26H,1-3H3,(H,23,25)/t17-/m0/s1 JLCBKZPEUMOYQE-KRWDZBQOSA-N 50258074 (S)-N-(2-chloro-4-(N,4-dimethylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide::CHEMBL521866 Oxysterols receptor LXR-beta 1500 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573632 104108903 CHEMBL521866 ZINC40953634 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151897 CCN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccccc1Cl InChI=1S/C18H17Cl2F3N2O4S/c1-3-25(30(28,29)15-7-5-4-6-12(15)19)11-8-9-14(13(20)10-11)24-16(26)17(2,27)18(21,22)23/h4-10,27H,3H2,1-2H3,(H,24,26) BAYWCFNEQZVNCY-UHFFFAOYSA-N 50258075 CHEMBL523211::N-(2-chloro-4-(2-chloro-N-ethylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta 7500 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573633 104108904 CHEMBL523211 ZINC40431271 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151898 CCN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccccc1Cl InChI=1S/C18H17Cl2F3N2O4S/c1-3-25(30(28,29)15-7-5-4-6-12(15)19)11-8-9-14(13(20)10-11)24-16(26)17(2,27)18(21,22)23/h4-10,27H,3H2,1-2H3,(H,24,26) BAYWCFNEQZVNCY-UHFFFAOYSA-N 50258075 CHEMBL523211::N-(2-chloro-4-(2-chloro-N-ethylphenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta 790 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573633 104108904 CHEMBL523211 ZINC40431271 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151899 CC(O)(C(=O)Nc1ccc(cc1Cl)N(Cc1ccccc1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F InChI=1S/C23H19Cl2F3N2O4S/c1-22(32,23(26,27)28)21(31)29-19-12-11-16(13-18(19)25)30(14-15-7-3-2-4-8-15)35(33,34)20-10-6-5-9-17(20)24/h2-13,32H,14H2,1H3,(H,29,31) XUPXFYHPDJNHNA-UHFFFAOYSA-N 50258076 CHEMBL494843::N-(4-(N-benzyl-2-chlorophenylsulfonamido)-2-chlorophenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573634 104108905 CHEMBL494843 ZINC49881647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151901 CC(O)(C(=O)Nc1ccc(cc1Cl)N(Cc1ccccc1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F InChI=1S/C23H19Cl2F3N2O4S/c1-22(32,23(26,27)28)21(31)29-19-12-11-16(13-18(19)25)30(14-15-7-3-2-4-8-15)35(33,34)20-10-6-5-9-17(20)24/h2-13,32H,14H2,1H3,(H,29,31) XUPXFYHPDJNHNA-UHFFFAOYSA-N 50258076 CHEMBL494843::N-(4-(N-benzyl-2-chlorophenylsulfonamido)-2-chlorophenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta 880 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573634 104108905 CHEMBL494843 ZINC49881647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151903 CN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(CCC(O)=O)cc1 InChI=1S/C20H20ClF3N2O6S/c1-19(30,20(22,23)24)18(29)25-16-9-6-13(11-15(16)21)26(2)33(31,32)14-7-3-12(4-8-14)5-10-17(27)28/h3-4,6-9,11,30H,5,10H2,1-2H3,(H,25,29)(H,27,28) JOGPAHVMRGIBSE-UHFFFAOYSA-N 50258173 3-(4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)phenyl)propanoic acid::CHEMBL492563 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258173&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573719 104108962 CHEMBL492563 ZINC40950855 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151905 CN(c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1)S(=O)(=O)c1ccc(CCC(O)=O)cc1 InChI=1S/C20H20ClF3N2O6S/c1-19(30,20(22,23)24)18(29)25-16-9-6-13(11-15(16)21)26(2)33(31,32)14-7-3-12(4-8-14)5-10-17(27)28/h3-4,6-9,11,30H,5,10H2,1-2H3,(H,25,29)(H,27,28) JOGPAHVMRGIBSE-UHFFFAOYSA-N 50258173 3-(4-(N-(3-chloro-4-(3,3,3-trifluoro-2-hydroxy-2-methylpropanamido)phenyl)-N-methylsulfamoyl)phenyl)propanoic acid::CHEMBL492563 Oxysterols receptor LXR-beta >100000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258173&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573719 104108962 CHEMBL492563 ZINC40950855 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151906 C[C@H](CC[C@@H]1OC1(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H44O2/c1-17(6-11-24-25(2,3)29-24)21-9-10-22-20-8-7-18-16-19(28)12-14-26(18,4)23(20)13-15-27(21,22)5/h7,17,19-24,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,24+,26+,27-/m1/s1 OSENKJZWYQXHBN-XVYZBDJZSA-N 20164 (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-dimethyloxiran-2-yl]butan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::24(S),25-epoxycholesterol::CHEMBL434302::Epoxycholesterol Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20164&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search CO1 6XBM,1P8D,6OT0 3247059 49688239 CHEMBL434302 2751 C15632 ZINC06201930 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151907 CC(O)(C(=O)Nc1ccc(cc1Cl)N(CC1CC1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F InChI=1S/C20H19Cl2F3N2O4S/c1-19(29,20(23,24)25)18(28)26-16-9-8-13(10-15(16)22)27(11-12-6-7-12)32(30,31)17-5-3-2-4-14(17)21/h2-5,8-10,12,29H,6-7,11H2,1H3,(H,26,28) BFQFDUADWFMIBS-UHFFFAOYSA-N 50258119 CHEMBL495020::N-(2-chloro-4-(2-chloro-N-(cyclopropylmethyl)phenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258119&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573677 104108927 CHEMBL495020 ZINC40431301 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151911 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 130 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151912 CC(O)(C(=O)Nc1ccc(cc1Cl)N(CC1CC1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F InChI=1S/C20H19Cl2F3N2O4S/c1-19(29,20(23,24)25)18(28)26-16-9-8-13(10-15(16)22)27(11-12-6-7-12)32(30,31)17-5-3-2-4-14(17)21/h2-5,8-10,12,29H,6-7,11H2,1H3,(H,26,28) BFQFDUADWFMIBS-UHFFFAOYSA-N 50258119 CHEMBL495020::N-(2-chloro-4-(2-chloro-N-(cyclopropylmethyl)phenylsulfonamido)phenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta 940 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258119&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573677 104108927 CHEMBL495020 ZINC40431301 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151913 CC(O)(C(=O)Nc1ccc(cc1Cl)N(CC=C)S(=O)(=O)c1ccccc1Cl)C(F)(F)F InChI=1S/C19H17Cl2F3N2O4S/c1-3-10-26(31(29,30)16-7-5-4-6-13(16)20)12-8-9-15(14(21)11-12)25-17(27)18(2,28)19(22,23)24/h3-9,11,28H,1,10H2,2H3,(H,25,27) NPQCUKWVPMFTSZ-UHFFFAOYSA-N 50258120 CHEMBL522370::N-(4-(N-allyl-2-chlorophenylsulfonamido)-2-chlorophenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258120&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573678 104108928 CHEMBL522370 ZINC40955248 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50151914 CC(O)(C(=O)Nc1ccc(cc1Cl)N(CC=C)S(=O)(=O)c1ccccc1Cl)C(F)(F)F InChI=1S/C19H17Cl2F3N2O4S/c1-3-10-26(31(29,30)16-7-5-4-6-13(16)20)12-8-9-15(14(21)11-12)25-17(27)18(2,28)19(22,23)24/h3-9,11,28H,1,10H2,2H3,(H,25,27) NPQCUKWVPMFTSZ-UHFFFAOYSA-N 50258120 CHEMBL522370::N-(4-(N-allyl-2-chlorophenylsulfonamido)-2-chlorophenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide Oxysterols receptor LXR-beta 580 ChEMBL 10.1016/j.bmcl.2009.02.039 10.7270/Q20C4VNS 19264481 Swahn, BM; Macsari, I; Viklund, J; Ohberg, L; Sjodin, J; Neelissen, J; Lindquist, J AstraZeneca R&D Södertälje http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258120&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44573678 104108928 CHEMBL522370 ZINC40955248 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50164259 CC(C)c1onc(c1COc1ccc(N(C)Cc2ccc(cc2)C(O)=O)c(n1)C(F)(F)F)-c1c(Cl)cccc1Cl InChI=1S/C28H24Cl2F3N3O4/c1-15(2)25-18(24(35-40-25)23-19(29)5-4-6-20(23)30)14-39-22-12-11-21(26(34-22)28(31,32)33)36(3)13-16-7-9-17(10-8-16)27(37)38/h4-12,15H,13-14H2,1-3H3,(H,37,38) LLIRGSLYYCOZDJ-UHFFFAOYSA-N 50323524 4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid::CHEMBL1209109 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2010.06.084 10.7270/Q21V5F52 20638278 Abel, U; Schluter, T; Schulz, A; Hambruch, E; Steeneck, C; Hornberger, M; Hoffmann, T; Perovic-Ottstadt, S; Kinzel, O; Burnet, M; Deuschle, U; Kremoser, C Phenex Pharmaceuticals AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323524&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24748569 117644845 CHEMBL1209109 ZINC58563901 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162278 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 170 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162279 CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1c(Cc2ccccc2)cnc2c(cccc12)C(F)(F)F InChI=1S/C30H22F3NO2S/c1-37(35,36)25-13-6-11-22(18-25)21-10-5-12-23(17-21)28-24(16-20-8-3-2-4-9-20)19-34-29-26(28)14-7-15-27(29)30(31,32)33/h2-15,17-19H,16H2,1H3 MYNWRKZLIIDPBU-UHFFFAOYSA-N 50317735 3-benzyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098401 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887797 104152096 CHEMBL1098401 ZINC49088346 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162280 CS(=O)(=O)c1ccc(cc1)-c1cccc(c1)-c1c(Cc2ccccc2)cnc2c(cccc12)C(F)(F)F InChI=1S/C30H22F3NO2S/c1-37(35,36)25-15-13-21(14-16-25)22-9-5-10-23(18-22)28-24(17-20-7-3-2-4-8-20)19-34-29-26(28)11-6-12-27(29)30(31,32)33/h2-16,18-19H,17H2,1H3 NTXMYMGYFCGBAL-UHFFFAOYSA-N 50317736 3-benzyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098402 Oxysterols receptor LXR-beta 3300 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887798 104152097 CHEMBL1098402 ZINC49113365 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162281 CS(=O)(=O)c1cc(c(F)cc1F)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C23H14F5NO2S/c1-32(30,31)21-11-17(19(24)12-20(21)25)14-5-2-4-13(10-14)15-8-9-29-22-16(15)6-3-7-18(22)23(26,27)28/h2-12H,1H3 UWFHFVAFWATDDO-UHFFFAOYSA-N 50317747 4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097140 Oxysterols receptor LXR-beta 4.9 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887924 104152108 CHEMBL1097140 ZINC49088591 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162282 CS(=O)(=O)c1cc(c(F)cc1F)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C23H14F5NO2S/c1-32(30,31)21-11-17(19(24)12-20(21)25)14-5-2-4-13(10-14)15-8-9-29-22-16(15)6-3-7-18(22)23(26,27)28/h2-12H,1H3 UWFHFVAFWATDDO-UHFFFAOYSA-N 50317747 4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097140 Oxysterols receptor LXR-beta 565 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887924 104152108 CHEMBL1097140 ZINC49088591 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162283 CS(=O)(=O)c1cc(ccc1F)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C23H15F4NO2S/c1-31(29,30)21-13-15(8-9-20(21)24)14-4-2-5-16(12-14)17-10-11-28-22-18(17)6-3-7-19(22)23(25,26)27/h2-13H,1H3 QIFYDQQBXMOQLW-UHFFFAOYSA-N 50317746 4-(4'-fluoro-3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097160 Oxysterols receptor LXR-beta 2.6 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887891 104152107 CHEMBL1097160 ZINC49784530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162284 CS(=O)(=O)c1cc(ccc1F)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C23H15F4NO2S/c1-31(29,30)21-13-15(8-9-20(21)24)14-4-2-5-16(12-14)17-10-11-28-22-18(17)6-3-7-19(22)23(25,26)27/h2-13H,1H3 QIFYDQQBXMOQLW-UHFFFAOYSA-N 50317746 4-(4'-fluoro-3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097160 Oxysterols receptor LXR-beta 512 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887891 104152107 CHEMBL1097160 ZINC49784530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162285 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 9 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162286 CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C23H16F3NO2S/c1-30(28,29)18-8-3-6-16(14-18)15-5-2-7-17(13-15)19-11-12-27-22-20(19)9-4-10-21(22)23(24,25)26/h2-14H,1H3 KIITVWQUUAGGON-UHFFFAOYSA-N 50317731 4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1095714 Oxysterols receptor LXR-beta 4.4 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317731&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44180521 104152092 CHEMBL1095714 ZINC43207092 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162287 CCCc1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C26H22F3NO2S/c1-3-7-20-16-30-25-22(12-6-13-23(25)26(27,28)29)24(20)19-10-4-8-17(14-19)18-9-5-11-21(15-18)33(2,31)32/h4-6,8-16H,3,7H2,1-2H3 DPAWQSUVLANLRD-UHFFFAOYSA-N 50317738 4-(3'-(methylsulfonyl)biphenyl-3-yl)-3-propyl-8-(trifluoromethyl)quinoline::CHEMBL1096719 Oxysterols receptor LXR-beta 3.8 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887800 104152099 CHEMBL1096719 ZINC49111459 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162288 CCS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C24H18F3NO2S/c1-2-31(29,30)19-9-4-7-17(15-19)16-6-3-8-18(14-16)20-12-13-28-23-21(20)10-5-11-22(23)24(25,26)27/h3-15H,2H2,1H3 VJEBBKVWKHODQJ-UHFFFAOYSA-N 50317740 4-(3'-(ethylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098831 Oxysterols receptor LXR-beta 33 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887852 104152101 CHEMBL1098831 ZINC49088222 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162289 CCc1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C25H20F3NO2S/c1-3-16-15-29-24-21(11-6-12-22(24)25(26,27)28)23(16)19-9-4-7-17(13-19)18-8-5-10-20(14-18)32(2,30)31/h4-15H,3H2,1-2H3 DRNWBBRZORIYEI-UHFFFAOYSA-N 50317737 3-ethyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098403 Oxysterols receptor LXR-beta 2.4 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887799 104152098 CHEMBL1098403 ZINC49088206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162290 CC(C)c1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C26H22F3NO2S/c1-16(2)22-15-30-25-21(11-6-12-23(25)26(27,28)29)24(22)19-9-4-7-17(13-19)18-8-5-10-20(14-18)33(3,31)32/h4-16H,1-3H3 ISMQLWMZRUKHEF-UHFFFAOYSA-N 50317739 3-isopropyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097799 Oxysterols receptor LXR-beta 4.1 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887851 104152100 CHEMBL1097799 ZINC49785001 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162291 CS(=O)(=O)c1ccc(cc1)-c1cccc(c1)-c1c(Cc2ccccc2)cnc2c(cccc12)C(F)(F)F InChI=1S/C30H22F3NO2S/c1-37(35,36)25-15-13-21(14-16-25)22-9-5-10-23(18-22)28-24(17-20-7-3-2-4-8-20)19-34-29-26(28)11-6-12-27(29)30(31,32)33/h2-16,18-19H,17H2,1H3 NTXMYMGYFCGBAL-UHFFFAOYSA-N 50317736 3-benzyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098402 Oxysterols receptor LXR-beta 109 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887798 104152097 CHEMBL1098402 ZINC49113365 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162292 CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1c(Cc2ccccc2)cnc2c(cccc12)C(F)(F)F InChI=1S/C30H22F3NO2S/c1-37(35,36)25-13-6-11-22(18-25)21-10-5-12-23(17-21)28-24(16-20-8-3-2-4-9-20)19-34-29-26(28)14-7-15-27(29)30(31,32)33/h2-15,17-19H,16H2,1H3 MYNWRKZLIIDPBU-UHFFFAOYSA-N 50317735 3-benzyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098401 Oxysterols receptor LXR-beta 1.5 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887797 104152096 CHEMBL1098401 ZINC49088346 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162293 CCc1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C25H20F3NO2S/c1-3-16-15-29-24-21(11-6-12-22(24)25(26,27)28)23(16)19-9-4-7-17(13-19)18-8-5-10-20(14-18)32(2,30)31/h4-15H,3H2,1-2H3 DRNWBBRZORIYEI-UHFFFAOYSA-N 50317737 3-ethyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098403 Oxysterols receptor LXR-beta 76 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887799 104152098 CHEMBL1098403 ZINC49088206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162294 CC(C)c1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C26H22F3NO2S/c1-16(2)22-15-30-25-21(11-6-12-23(25)26(27,28)29)24(22)19-9-4-7-17(13-19)18-8-5-10-20(14-18)33(3,31)32/h4-16H,1-3H3 ISMQLWMZRUKHEF-UHFFFAOYSA-N 50317739 3-isopropyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1097799 Oxysterols receptor LXR-beta 91 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887851 104152100 CHEMBL1097799 ZINC49785001 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162295 CCCc1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C26H22F3NO2S/c1-3-7-20-16-30-25-22(12-6-13-23(25)26(27,28)29)24(20)19-10-4-8-17(14-19)18-9-5-11-21(15-18)33(2,31)32/h4-6,8-16H,3,7H2,1-2H3 DPAWQSUVLANLRD-UHFFFAOYSA-N 50317738 4-(3'-(methylsulfonyl)biphenyl-3-yl)-3-propyl-8-(trifluoromethyl)quinoline::CHEMBL1096719 Oxysterols receptor LXR-beta 106 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887800 104152099 CHEMBL1096719 ZINC49111459 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157956 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 13 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157957 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(CO)c2)c1)C(F)(F)F InChI=1S/C24H18F3NO2/c1-15-13-28-23-20(9-4-10-21(23)24(25,26)27)22(15)17-6-3-8-19(12-17)30-18-7-2-5-16(11-18)14-29/h2-13,29H,14H2,1H3 CQEKMSRTDPXHST-UHFFFAOYSA-N 35094 biarylether alcohol quinoline, 5f Oxysterols receptor LXR-beta 12 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35094&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16727105 85753174 ZINC45352446 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157958 Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1 InChI=1S/C23H18ClNO3S/c1-15-14-25-23-20(10-5-11-21(23)24)22(15)16-6-3-7-17(12-16)28-18-8-4-9-19(13-18)29(2,26)27/h3-14H,1-2H3 PBQUJALWEDBRLW-UHFFFAOYSA-N 50305072 8-chloro-3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline::CHEMBL595782 Oxysterols receptor LXR-beta 3.4 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100152 104159433 CHEMBL595782 ZINC45351975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157959 Cc1cnc2c(cccc2c1-c1cccc(Oc2cc(Cl)cc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H17ClF3NO3S/c1-14-13-29-23-20(7-4-8-21(23)24(26,27)28)22(14)15-5-3-6-17(9-15)32-18-10-16(25)11-19(12-18)33(2,30)31/h3-13H,1-2H3 QRIKQMLMSCHVRS-UHFFFAOYSA-N 50305059 4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL594176 Oxysterols receptor LXR-beta 28 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305059&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100307 104159420 CHEMBL594176 ZINC45351651 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157960 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C30H22F3NO3S/c1-38(35,36)25-13-6-12-24(18-25)37-23-11-5-10-21(17-23)28-22(16-20-8-3-2-4-9-20)19-34-29-26(28)14-7-15-27(29)30(31,32)33/h2-15,17-19H,16H2,1H3 DZOUMAUJJDVJHY-UHFFFAOYSA-N 50305075 3-benzyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL592506 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100311 104159436 CHEMBL592506 ZINC49757176 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157961 Cc1cnc2c(cccc2c1-c1cccc(Oc2cc(F)cc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H17F4NO3S/c1-14-13-29-23-20(7-4-8-21(23)24(26,27)28)22(14)15-5-3-6-17(9-15)32-18-10-16(25)11-19(12-18)33(2,30)31/h3-13H,1-2H3 HXANPPNXWQVOEO-UHFFFAOYSA-N 50305060 4-(3-(3-fluoro-5-(methylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL594175 Oxysterols receptor LXR-beta 6.6 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305060&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100151 104159421 CHEMBL594175 ZINC45351647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157962 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H18F3NO3S/c1-15-14-28-23-20(10-5-11-21(23)24(25,26)27)22(15)16-6-3-7-17(12-16)31-18-8-4-9-19(13-18)32(2,29)30/h3-14H,1-2H3 ZDUOYBOFMKORCT-UHFFFAOYSA-N 50305077 3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595689 Oxysterols receptor LXR-beta 2.4 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100150 104159438 CHEMBL595689 ZINC45351156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157963 Cc1cnc2c(cccc2c1-c1cccc(Oc2ccc(cc2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H18F3NO3S/c1-15-14-28-23-20(7-4-8-21(23)24(25,26)27)22(15)16-5-3-6-18(13-16)31-17-9-11-19(12-10-17)32(2,29)30/h3-14H,1-2H3 ZVLHOXBSTALIAV-UHFFFAOYSA-N 50305078 3-methyl-4-(3-(4-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL593884 Oxysterols receptor LXR-beta 153 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100147 104159439 CHEMBL593884 ZINC45352221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157964 CC(C)CCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C28H26F3NO3S/c1-18(2)13-14-36(33,34)23-10-5-9-22(16-23)35-21-8-4-7-20(15-21)26-19(3)17-32-27-24(26)11-6-12-25(27)28(29,30)31/h4-12,15-18H,13-14H2,1-3H3 MVQGOFQHJVGQCO-UHFFFAOYSA-N 50305065 4-(3-(3-(isopentylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL594174 Oxysterols receptor LXR-beta 118 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25099839 104159426 CHEMBL594174 ZINC45351643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157965 COc1ccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)cc1S(C)(=O)=O InChI=1S/C25H20F3NO4S/c1-15-14-29-24-19(8-5-9-20(24)25(26,27)28)23(15)16-6-4-7-17(12-16)33-18-10-11-21(32-2)22(13-18)34(3,30)31/h4-14H,1-3H3 SYTLPMIZCIQSJE-UHFFFAOYSA-N 50305061 4-(3-(4-methoxy-3-(methylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL607090 Oxysterols receptor LXR-beta 56 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102122 104159422 CHEMBL607090 ZINC45388881 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157966 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(Cl)cccc23)c1 InChI=1S/C29H22ClNO3S/c1-35(32,33)25-13-6-12-24(18-25)34-23-11-5-10-21(17-23)28-22(16-20-8-3-2-4-9-20)19-31-29-26(28)14-7-15-27(29)30/h2-15,17-19H,16H2,1H3 JWRIUHZELXTXLP-UHFFFAOYSA-N 50305073 3-benzyl-8-chloro-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline::CHEMBL606539 Oxysterols receptor LXR-beta 3.3 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100149 104159434 CHEMBL606539 ZINC45386153 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157967 CC(C)CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C27H24F3NO3S/c1-17(2)16-35(32,33)22-10-5-9-21(14-22)34-20-8-4-7-19(13-20)25-18(3)15-31-26-23(25)11-6-12-24(26)27(28,29)30/h4-15,17H,16H2,1-3H3 PDIDLFFWXHKWMR-UHFFFAOYSA-N 50305066 4-(3-(3-(isobutylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL595345 Oxysterols receptor LXR-beta 61 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25099838 104159427 CHEMBL595345 ZINC45350072 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157968 CNC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C24H19ClN2O2/c1-15-14-27-23-20(10-5-11-21(23)25)22(15)16-6-3-8-18(12-16)29-19-9-4-7-17(13-19)24(28)26-2/h3-14H,1-2H3,(H,26,28) CGUCJIOARZYDCJ-UHFFFAOYSA-N 35108 biarylether amide quinoline, 4i Oxysterols receptor LXR-beta 125 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35108&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44472997 85753188 ZINC40866537 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157969 COCCCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C27H24F3NO4S/c1-18-17-31-26-23(11-5-12-24(26)27(28,29)30)25(18)19-7-3-8-20(15-19)35-21-9-4-10-22(16-21)36(32,33)14-6-13-34-2/h3-5,7-12,15-17H,6,13-14H2,1-2H3 PLHRETMILCOKED-UHFFFAOYSA-N 50305062 4-(3-(3-(3-methoxypropylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL595804 Oxysterols receptor LXR-beta 19 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305062&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25099991 104159423 CHEMBL595804 ZINC45352002 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157970 Cc1cnc2c(cccc2c1-c1cccc(Oc2ccccc2S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H18F3NO3S/c1-15-14-28-23-18(9-6-10-19(23)24(25,26)27)22(15)16-7-5-8-17(13-16)31-20-11-3-4-12-21(20)32(2,29)30/h3-14H,1-2H3 ZTQHPDHGMFCHSE-UHFFFAOYSA-N 50305076 3-methyl-4-(3-(2-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595045 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25099837 104159437 CHEMBL595045 ZINC45351827 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157971 CC(C)S(=O)(=O)c1cccc(Oc2cccc(c2)-c2ccnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C25H20F3NO3S/c1-16(2)33(30,31)20-9-4-8-19(15-20)32-18-7-3-6-17(14-18)21-12-13-29-24-22(21)10-5-11-23(24)25(26,27)28/h3-16H,1-2H3 MOQUFKNADUILIJ-UHFFFAOYSA-N 50305067 4-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595344 Oxysterols receptor LXR-beta 4 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305067&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100922 104159428 CHEMBL595344 ZINC45350069 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157972 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(=O)(=O)CCC(C)(C)O)c1)C(F)(F)F InChI=1S/C28H26F3NO4S/c1-18-17-32-26-23(11-6-12-24(26)28(29,30)31)25(18)19-7-4-8-20(15-19)36-21-9-5-10-22(16-21)37(34,35)14-13-27(2,3)33/h4-12,15-17,33H,13-14H2,1-3H3 UCPCLSOVORSWOU-UHFFFAOYSA-N 50305063 2-methyl-4-(3-(3-(3-methyl-8-(trifluoromethyl)quinolin-4-yl)phenoxy)phenylsulfonyl)butan-2-ol::CHEMBL604582 Oxysterols receptor LXR-beta 121 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305063&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100148 104159424 CHEMBL604582 ZINC49767771 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157973 CCCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C26H22F3NO3S/c1-3-13-34(31,32)21-10-5-9-20(15-21)33-19-8-4-7-18(14-19)24-17(2)16-30-25-22(24)11-6-12-23(25)26(27,28)29/h4-12,14-16H,3,13H2,1-2H3 HRXRTZUZVWAYOB-UHFFFAOYSA-N 50305069 3-methyl-4-(3-(3-(propylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595580 Oxysterols receptor LXR-beta 23 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305069&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102118 104159430 CHEMBL595580 ZINC45349140 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157974 CC(C)S(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C26H22F3NO3S/c1-16(2)34(31,32)21-10-5-9-20(14-21)33-19-8-4-7-18(13-19)24-17(3)15-30-25-22(24)11-6-12-23(25)26(27,28)29/h4-16H,1-3H3 YYDPUXBLDMRZQE-UHFFFAOYSA-N 50305068 4-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL595113 Oxysterols receptor LXR-beta 7.9 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305068&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102119 104159429 CHEMBL595113 ZINC45351054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157975 CCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C25H20F3NO3S/c1-3-33(30,31)20-10-5-9-19(14-20)32-18-8-4-7-17(13-18)23-16(2)15-29-24-21(23)11-6-12-22(24)25(26,27)28/h4-15H,3H2,1-2H3 ZIMHQMXADUASSG-UHFFFAOYSA-N 50305070 4-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL593473 Oxysterols receptor LXR-beta 6.1 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102117 104159431 CHEMBL593473 ZINC45352801 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157976 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(=O)(=O)CCCO)c1)C(F)(F)F InChI=1S/C26H22F3NO4S/c1-17-16-30-25-22(10-4-11-23(25)26(27,28)29)24(17)18-6-2-7-19(14-18)34-20-8-3-9-21(15-20)35(32,33)13-5-12-31/h2-4,6-11,14-16,31H,5,12-13H2,1H3 LJZFYKYOXOCPDD-UHFFFAOYSA-N 50305064 3-(3-(3-(3-methyl-8-(trifluoromethyl)quinolin-4-yl)phenoxy)phenylsulfonyl)propan-1-ol::CHEMBL593472 Oxysterols receptor LXR-beta 4.7 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305064&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25099990 104159425 CHEMBL593472 ZINC45352158 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157977 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2ccnc3c(Cl)cccc23)c1 InChI=1S/C22H16ClNO3S/c1-28(25,26)18-8-3-7-17(14-18)27-16-6-2-5-15(13-16)19-11-12-24-22-20(19)9-4-10-21(22)23/h2-14H,1H3 IKEBXOQTSPUHRL-UHFFFAOYSA-N 50305071 8-chloro-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline::CHEMBL593471 Oxysterols receptor LXR-beta 129 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46226975 104159432 CHEMBL593471 ZINC45352154 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50157978 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2ccnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C23H16F3NO3S/c1-31(28,29)18-8-3-7-17(14-18)30-16-6-2-5-15(13-16)19-11-12-27-22-20(19)9-4-10-21(22)23(24,25)26/h2-14H,1H3 DZEKZLIXNYUATR-UHFFFAOYSA-N 50305074 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::4-{3-[3-(methylsulfonyl)phenoxy]phenyl}-8-(trifluoromethyl)quinoline::CHEMBL593241 Oxysterols receptor LXR-beta 40 ChEMBL 10.1016/j.bmcl.2009.10.132 10.7270/Q2KW5G4B 19932617 Bernotas, RC; Singhaus, RR; Kaufman, DH; Travins, JM; Ullrich, JW; Unwalla, R; Quinet, E; Evans, M; Nambi, P; Olland, A; Kauppi, B; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 61X 3KFC 25100472 104159435 CHEMBL593241 ZINC44460342 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162369 CCS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C24H18F3NO2S/c1-2-31(29,30)19-9-4-7-17(15-19)16-6-3-8-18(14-16)20-12-13-28-23-21(20)10-5-11-22(23)24(25,26)27/h3-15H,2H2,1H3 VJEBBKVWKHODQJ-UHFFFAOYSA-N 50317740 4-(3'-(ethylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098831 Oxysterols receptor LXR-beta 1080 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887852 104152101 CHEMBL1098831 ZINC49088222 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162370 CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C23H16F3NO2S/c1-30(28,29)18-8-3-6-16(14-18)15-5-2-7-17(13-15)19-11-12-27-22-20(19)9-4-10-21(22)23(24,25)26/h2-14H,1H3 KIITVWQUUAGGON-UHFFFAOYSA-N 50317731 4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1095714 Oxysterols receptor LXR-beta 525 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317731&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44180521 104152092 CHEMBL1095714 ZINC43207092 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162371 CS(=O)(=O)c1ccc(cc1)-c1cccc(c1)-c1ccnc2c(cccc12)C(F)(F)F InChI=1S/C23H16F3NO2S/c1-30(28,29)18-10-8-15(9-11-18)16-4-2-5-17(14-16)19-12-13-27-22-20(19)6-3-7-21(22)23(24,25)26/h2-14H,1H3 BZROSBGJVTZPAW-UHFFFAOYSA-N 50317732 4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1095715 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317732&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887743 104152093 CHEMBL1095715 ZINC49784696 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162372 Cc1cnc2c(cccc2c1-c1cccc(c1)-c1ccc(F)c(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H17F4NO2S/c1-14-13-29-23-18(7-4-8-19(23)24(26,27)28)22(14)17-6-3-5-15(11-17)16-9-10-20(25)21(12-16)32(2,30)31/h3-13H,1-2H3 BKINFWHEJAZZTL-UHFFFAOYSA-N 50317744 4-(4'-fluoro-3'-(methylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL1097158 Oxysterols receptor LXR-beta 161 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887889 104152105 CHEMBL1097158 ZINC49126288 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162373 Cc1cnc2c(cccc2c1-c1cccc(c1)-c1cc(c(F)cc1F)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H16F5NO2S/c1-13-12-30-23-16(7-4-8-18(23)24(27,28)29)22(13)15-6-3-5-14(9-15)17-10-21(33(2,31)32)20(26)11-19(17)25/h3-12H,1-2H3 GKRQECRQGLCHTJ-UHFFFAOYSA-N 50317745 4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL1097159 Oxysterols receptor LXR-beta 195 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887890 104152106 CHEMBL1097159 ZINC49784529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162374 Cc1ccc(cc1S(C)(=O)=O)-c1cccc(c1)-c1c(C)cnc2c(cccc12)C(F)(F)F InChI=1S/C25H20F3NO2S/c1-15-10-11-18(13-22(15)32(3,30)31)17-6-4-7-19(12-17)23-16(2)14-29-24-20(23)8-5-9-21(24)25(26,27)28/h4-14H,1-3H3 APHRFSGOWKZUGE-UHFFFAOYSA-N 50317742 3-methyl-4-(4'-methyl-3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098850 Oxysterols receptor LXR-beta 175 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887854 104152103 CHEMBL1098850 ZINC49793110 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162375 COc1ccc(cc1S(C)(=O)=O)-c1cccc(c1)-c1c(C)cnc2c(cccc12)C(F)(F)F InChI=1S/C25H20F3NO3S/c1-15-14-29-24-19(8-5-9-20(24)25(26,27)28)23(15)18-7-4-6-16(12-18)17-10-11-21(32-2)22(13-17)33(3,30)31/h4-14H,1-3H3 MKHOYUJKXDXRQG-UHFFFAOYSA-N 50317743 4-(4'-methoxy-3'-(methylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL1099133 Oxysterols receptor LXR-beta 629 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887888 104152104 CHEMBL1099133 ZINC49793213 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162376 Cc1cnc2c(cccc2c1-c1cccc(c1)-c1ccc(F)c(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H17F4NO2S/c1-14-13-29-23-18(7-4-8-19(23)24(26,27)28)22(14)17-6-3-5-15(11-17)16-9-10-20(25)21(12-16)32(2,30)31/h3-13H,1-2H3 BKINFWHEJAZZTL-UHFFFAOYSA-N 50317744 4-(4'-fluoro-3'-(methylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL1097158 Oxysterols receptor LXR-beta 1.7 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887889 104152105 CHEMBL1097158 ZINC49126288 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162377 Cc1cnc2c(cccc2c1-c1cccc(c1)-c1cc(c(F)cc1F)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H16F5NO2S/c1-13-12-30-23-16(7-4-8-18(23)24(27,28)29)22(13)15-6-3-5-14(9-15)17-10-21(33(2,31)32)20(26)11-19(17)25/h3-12H,1-2H3 GKRQECRQGLCHTJ-UHFFFAOYSA-N 50317745 4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL1097159 Oxysterols receptor LXR-beta 3.3 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887890 104152106 CHEMBL1097159 ZINC49784529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162378 Cc1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H18F3NO2S/c1-15-14-28-23-20(10-5-11-21(23)24(25,26)27)22(15)18-8-3-6-16(12-18)17-7-4-9-19(13-17)31(2,29)30/h3-14H,1-2H3 NVDRYPHMVKODMP-UHFFFAOYSA-N 50317733 3-methyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1094741 Oxysterols receptor LXR-beta 284 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317733&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887744 104152094 CHEMBL1094741 ZINC49072207 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162379 Cc1cnc2c(cccc2c1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H18F3NO2S/c1-15-14-28-23-20(7-4-8-21(23)24(25,26)27)22(15)18-6-3-5-17(13-18)16-9-11-19(12-10-16)31(2,29)30/h3-14H,1-2H3 AWHRFIKOWGDBRL-UHFFFAOYSA-N 50317734 3-methyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1094742 Oxysterols receptor LXR-beta 355 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317734&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887745 104152095 CHEMBL1094742 ZINC49113195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162380 Cc1cnc2c(cccc2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H18F3NO2S/c1-15-14-28-23-20(10-5-11-21(23)24(25,26)27)22(15)18-8-3-6-16(12-18)17-7-4-9-19(13-17)31(2,29)30/h3-14H,1-2H3 NVDRYPHMVKODMP-UHFFFAOYSA-N 50317733 3-methyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1094741 Oxysterols receptor LXR-beta 1.8 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317733&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887744 104152094 CHEMBL1094741 ZINC49072207 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162381 CCS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1c(C)cnc2c(cccc12)C(F)(F)F InChI=1S/C25H20F3NO2S/c1-3-32(30,31)20-10-5-8-18(14-20)17-7-4-9-19(13-17)23-16(2)15-29-24-21(23)11-6-12-22(24)25(26,27)28/h4-15H,3H2,1-2H3 JVIDKHNOLQEIJP-UHFFFAOYSA-N 50317741 4-(3'-(ethylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL1098832 Oxysterols receptor LXR-beta 580 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887853 104152102 CHEMBL1098832 ZINC49113947 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162382 Cc1ccc(cc1S(C)(=O)=O)-c1cccc(c1)-c1c(C)cnc2c(cccc12)C(F)(F)F InChI=1S/C25H20F3NO2S/c1-15-10-11-18(13-22(15)32(3,30)31)17-6-4-7-19(12-17)23-16(2)14-29-24-20(23)8-5-9-21(24)25(26,27)28/h4-14H,1-3H3 APHRFSGOWKZUGE-UHFFFAOYSA-N 50317742 3-methyl-4-(4'-methyl-3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline::CHEMBL1098850 Oxysterols receptor LXR-beta 3.2 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887854 104152103 CHEMBL1098850 ZINC49793110 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50162383 CCS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1c(C)cnc2c(cccc12)C(F)(F)F InChI=1S/C25H20F3NO2S/c1-3-32(30,31)20-10-5-8-18(14-20)17-7-4-9-19(13-17)23-16(2)15-29-24-21(23)11-6-12-22(24)25(26,27)28/h4-15H,3H2,1-2H3 JVIDKHNOLQEIJP-UHFFFAOYSA-N 50317741 4-(3'-(ethylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline::CHEMBL1098832 Oxysterols receptor LXR-beta 5.2 ChEMBL 10.1016/j.bmcl.2010.03.031 10.7270/Q2TD9XJZ 20382019 Ullrich, JW; Morris, R; Bernotas, RC; Travins, JM; Jetter, J; Unwalla, R; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Enroth, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46887853 104152102 CHEMBL1098832 ZINC49113947 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158060 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H17F3N2O4S/c1-34(31,32)17-8-3-7-16(12-17)33-15-6-2-5-14(11-15)21-18-9-4-10-20(24(25,26)27)22(18)29-13-19(21)23(28)30/h2-13H,1H3,(H2,28,30) DRRBJCNZGQGKSK-UHFFFAOYSA-N 50305504 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL591582 Oxysterols receptor LXR-beta 18 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305504&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46191160 104159865 CHEMBL591582 ZINC45337727 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158061 CCNC(=O)c1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C26H21F3N2O4S/c1-3-30-25(32)21-15-31-24-20(11-6-12-22(24)26(27,28)29)23(21)16-7-4-8-17(13-16)35-18-9-5-10-19(14-18)36(2,33)34/h4-15H,3H2,1-2H3,(H,30,32) SNTQPMQPAACQAY-UHFFFAOYSA-N 50305502 CHEMBL600851::N-ethyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide Oxysterols receptor LXR-beta 730 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305502&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225115 104159863 CHEMBL600851 ZINC45373477 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158062 CNC(=O)c1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C25H19F3N2O4S/c1-29-24(31)20-14-30-23-19(10-5-11-21(23)25(26,27)28)22(20)15-6-3-7-16(12-15)34-17-8-4-9-18(13-17)35(2,32)33/h3-14H,1-2H3,(H,29,31) XRICXMCEEJORLW-UHFFFAOYSA-N 50305503 CHEMBL591815::N-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide Oxysterols receptor LXR-beta 367 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305503&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225114 104159864 CHEMBL591815 ZINC45337020 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158063 CCOC(=O)c1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C26H20F3NO5S/c1-3-34-25(31)21-15-30-24-20(11-6-12-22(24)26(27,28)29)23(21)16-7-4-8-17(13-16)35-18-9-5-10-19(14-18)36(2,32)33/h4-15H,3H2,1-2H3 OWWNUAVAXAAAAM-UHFFFAOYSA-N 50305501 CHEMBL590098::ethyl 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxylate Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305501&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102125 104159862 CHEMBL590098 ZINC45339392 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158066 CS(=O)(=O)c1cc(Cl)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H16ClF3N2O4S/c1-35(32,33)17-10-14(25)9-16(11-17)34-15-5-2-4-13(8-15)21-18-6-3-7-20(24(26,27)28)22(18)30-12-19(21)23(29)31/h2-12H,1H3,(H2,29,31) OXAVBDIDWNTRGP-UHFFFAOYSA-N 50305494 4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL602446 Oxysterols receptor LXR-beta 62 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225196 104159855 CHEMBL602446 ZINC49767820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158067 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(CN)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C24H19F3N2O3S/c1-33(30,31)19-8-3-7-18(12-19)32-17-6-2-5-15(11-17)22-16(13-28)14-29-23-20(22)9-4-10-21(23)24(25,26)27/h2-12,14H,13,28H2,1H3 RKGUCTQUPQWZOT-UHFFFAOYSA-N 50305497 (4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinolin-3-yl)methanamine::CHEMBL590584 Oxysterols receptor LXR-beta 77 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305497&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225152 104159858 CHEMBL590584 ZINC45338951 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158070 CS(=O)(=O)c1cc(F)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H16F4N2O4S/c1-35(32,33)17-10-14(25)9-16(11-17)34-15-5-2-4-13(8-15)21-18-6-3-7-20(24(26,27)28)22(18)30-12-19(21)23(29)31/h2-12H,1H3,(H2,29,31) BHOVYPMEYZFYON-UHFFFAOYSA-N 50305495 4-(3-(3-fluoro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL590828 Oxysterols receptor LXR-beta 18 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305495&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225195 104159856 CHEMBL590828 ZINC45338961 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158072 CCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C25H19F3N2O4S/c1-2-35(32,33)18-9-4-8-17(13-18)34-16-7-3-6-15(12-16)22-19-10-5-11-21(25(26,27)28)23(19)30-14-20(22)24(29)31/h3-14H,2H2,1H3,(H2,29,31) CKHYMMLNOQQEMV-UHFFFAOYSA-N 50305493 4-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL589613 Oxysterols receptor LXR-beta 11 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305493&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225197 104159854 CHEMBL589613 ZINC45339129 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158076 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 9 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158077 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3ccccc23)C(N)=O)c1 InChI=1S/C23H18N2O4S/c1-30(27,28)18-9-5-8-17(13-18)29-16-7-4-6-15(12-16)22-19-10-2-3-11-21(19)25-14-20(22)23(24)26/h2-14H,1H3,(H2,24,26) BRIMRPVALXEWHB-UHFFFAOYSA-N 50305488 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline-3-carboxamide::CHEMBL606862 Oxysterols receptor LXR-beta 2850 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305488&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225296 104159849 CHEMBL606862 ZINC45384959 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158078 CCCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C26H21F3N2O4S/c1-2-12-36(33,34)19-9-4-8-18(14-19)35-17-7-3-6-16(13-17)23-20-10-5-11-22(26(27,28)29)24(20)31-15-21(23)25(30)32/h3-11,13-15H,2,12H2,1H3,(H2,30,32) JSBIMLQXMQAXBB-UHFFFAOYSA-N 50305492 4-(3-(3-(propylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL606139 Oxysterols receptor LXR-beta 57 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305492&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225243 104159853 CHEMBL606139 ZINC45384821 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158079 Cc1cccc2c(-c3cccc(Oc4cccc(c4)S(C)(=O)=O)c3)c(cnc12)C(N)=O InChI=1S/C24H20N2O4S/c1-15-6-3-11-20-22(21(24(25)27)14-26-23(15)20)16-7-4-8-17(12-16)30-18-9-5-10-19(13-18)31(2,28)29/h3-14H,1-2H3,(H2,25,27) XBDCCVVGSIGGTL-UHFFFAOYSA-N 50305490 8-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline-3-carboxamide::CHEMBL604259 Oxysterols receptor LXR-beta 28 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305490&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225245 104159851 CHEMBL604259 ZINC45390939 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158166 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(Cl)cccc23)C(N)=O)c1 InChI=1S/C23H17ClN2O4S/c1-31(28,29)17-8-3-7-16(12-17)30-15-6-2-5-14(11-15)21-18-9-4-10-20(24)22(18)26-13-19(21)23(25)27/h2-13H,1H3,(H2,25,27) AIOWJRXDKURKOW-UHFFFAOYSA-N 50305487 8-chloro-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline-3-carboxamide::CHEMBL593267 Oxysterols receptor LXR-beta 16 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305487&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46191159 104159848 CHEMBL593267 ZINC45347234 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158206 CC(C)S(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C26H21F3N2O4S/c1-15(2)36(33,34)19-9-4-8-18(13-19)35-17-7-3-6-16(12-17)23-20-10-5-11-22(26(27,28)29)24(20)31-14-21(23)25(30)32/h3-15H,1-2H3,(H2,30,32) BYZAOZSASXJAQT-UHFFFAOYSA-N 50305491 4-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL593739 Oxysterols receptor LXR-beta 5 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305491&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225244 104159852 CHEMBL593739 ZINC45347293 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158214 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H17F3N2O4S/c1-34(31,32)17-8-3-7-16(12-17)33-15-6-2-5-14(11-15)21-18-9-4-10-20(24(25,26)27)22(18)29-13-19(21)23(28)30/h2-13H,1H3,(H2,28,30) DRRBJCNZGQGKSK-UHFFFAOYSA-N 50305504 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL591582 Oxysterols receptor LXR-beta 1600 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305504&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46191160 104159865 CHEMBL591582 ZINC45337727 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158215 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(F)cccc23)C(N)=O)c1 InChI=1S/C23H17FN2O4S/c1-31(28,29)17-8-3-7-16(12-17)30-15-6-2-5-14(11-15)21-18-9-4-10-20(24)22(18)26-13-19(21)23(25)27/h2-13H,1H3,(H2,25,27) POECRYKCKXHVLF-UHFFFAOYSA-N 50305489 8-fluoro-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline-3-carboxamide::CHEMBL593740 Oxysterols receptor LXR-beta 590 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305489&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225246 104159850 CHEMBL593740 ZINC45347296 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158216 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(O)=O)c1 InChI=1S/C24H16F3NO5S/c1-34(31,32)17-8-3-7-16(12-17)33-15-6-2-5-14(11-15)21-18-9-4-10-20(24(25,26)27)22(18)28-13-19(21)23(29)30/h2-13H,1H3,(H,29,30) HRCBWCKPBWZCRB-UHFFFAOYSA-N 50305500 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxylic acid::CHEMBL590350 Oxysterols receptor LXR-beta 1076 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305500&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25102124 104159861 CHEMBL590350 ZINC45339175 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158217 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)-n2cnnn2)c1 InChI=1S/C24H16F3N5O3S/c1-36(33,34)18-8-3-7-17(12-18)35-16-6-2-5-15(11-16)22-19-9-4-10-20(24(25,26)27)23(19)28-13-21(22)32-14-29-30-31-32/h2-14H,1H3 NLXFYNCHNZGZBT-UHFFFAOYSA-N 50305498 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-3-(1H-tetrazol-1-yl)-8-(trifluoromethyl)quinoline::CHEMBL590351 Oxysterols receptor LXR-beta 5294 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305498&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225151 104159859 CHEMBL590351 ZINC45339400 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158218 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(Cl)cccc23)C(N)=O)c1 InChI=1S/C23H17ClN2O4S/c1-31(28,29)17-8-3-7-16(12-17)30-15-6-2-5-14(11-15)21-18-9-4-10-20(24)22(18)26-13-19(21)23(25)27/h2-13H,1H3,(H2,25,27) AIOWJRXDKURKOW-UHFFFAOYSA-N 50305487 8-chloro-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline-3-carboxamide::CHEMBL593267 Oxysterols receptor LXR-beta 630 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305487&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46191159 104159848 CHEMBL593267 ZINC45347234 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158219 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C#N)c1 InChI=1S/C24H15F3N2O3S/c1-33(30,31)19-8-3-7-18(12-19)32-17-6-2-5-15(11-17)22-16(13-28)14-29-23-20(22)9-4-10-21(23)24(25,26)27/h2-12,14H,1H3 DHCPTZAZDOXILJ-UHFFFAOYSA-N 50305499 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carbonitrile::CHEMBL600244 Oxysterols receptor LXR-beta 2.2 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305499&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25099842 104159860 CHEMBL600244 ZINC45372949 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158221 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H18F3NO3S/c1-15-14-28-23-20(10-5-11-21(23)24(25,26)27)22(15)16-6-3-7-17(12-16)31-18-8-4-9-19(13-18)32(2,29)30/h3-14H,1-2H3 ZDUOYBOFMKORCT-UHFFFAOYSA-N 50305077 3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595689 Oxysterols receptor LXR-beta 1 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100150 104159438 CHEMBL595689 ZINC45351156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158222 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta 3670 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158223 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=N)c1 InChI=1S/C24H18F3N3O3S/c1-34(31,32)17-8-3-7-16(12-17)33-15-6-2-5-14(11-15)21-18-9-4-10-20(24(25,26)27)22(18)30-13-19(21)23(28)29/h2-13H,1H3,(H3,28,29) ORZCTXQPXYCOAF-UHFFFAOYSA-N 50305496 4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboximidamide::CHEMBL590586 Oxysterols receptor LXR-beta 5133 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305496&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225194 104159857 CHEMBL590586 ZINC45338955 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158225 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 170 ChEMBL 10.1016/j.bmcl.2009.11.062 10.7270/Q2W66KV8 19962892 Hu, B; Bernotas, R; Unwalla, R; Collini, M; Quinet, E; Feingold, I; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Evans, M; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158371 CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C21H15F3N2O3S/c1-30(27,28)17-8-3-7-16(12-17)29-15-6-2-5-14(11-15)26-13-25-20-18(21(22,23)24)9-4-10-19(20)26/h2-13H,1H3 ZVQPSFBFGZWVGY-UHFFFAOYSA-N 50306067 1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL595222 Oxysterols receptor LXR-beta 882 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306067&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137303 104160428 CHEMBL595222 ZINC45339738 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158372 CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(nc3c(cccc23)C(F)(F)F)C(F)(F)F)c1 InChI=1S/C22H14F6N2O3S/c1-34(31,32)16-8-3-7-15(12-16)33-14-6-2-5-13(11-14)30-18-10-4-9-17(21(23,24)25)19(18)29-20(30)22(26,27)28/h2-12H,1H3 SELLUNCDLWGEEU-UHFFFAOYSA-N 50306068 1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-2,4-bis(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL605730 Oxysterols receptor LXR-beta 5.1 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306068&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137575 104160429 CHEMBL605730 ZINC43206279 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158373 CC(C)S(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2c(C)nc3c(Cl)cccc23)c1 InChI=1S/C23H20Cl2N2O3S/c1-14(2)31(28,29)18-7-4-6-16(12-18)30-17-10-11-19(24)22(13-17)27-15(3)26-23-20(25)8-5-9-21(23)27/h4-14H,1-3H3 ZSOMYKQAXFPKDY-UHFFFAOYSA-N 50306081 4-chloro-1-(2-chloro-5-(3-(isopropylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL595454 Oxysterols receptor LXR-beta 36 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137982 104160442 CHEMBL595454 ZINC45351093 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158374 CC(C)Cc1nc2c(cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C25H23F3N2O3S/c1-16(2)13-23-29-24-21(25(26,27)28)11-6-12-22(24)30(23)17-7-4-8-18(14-17)33-19-9-5-10-20(15-19)34(3,31)32/h4-12,14-16H,13H2,1-3H3 GBEWPJJHRRWGJD-UHFFFAOYSA-N 50306072 2-isobutyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL595012 Oxysterols receptor LXR-beta 3.2 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42641974 104160433 CHEMBL595012 ZINC43206278 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158375 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H18F3NO3S/c1-15-14-28-23-20(10-5-11-21(23)24(25,26)27)22(15)16-6-3-7-17(12-16)31-18-8-4-9-19(13-18)32(2,29)30/h3-14H,1-2H3 ZDUOYBOFMKORCT-UHFFFAOYSA-N 50305077 3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595689 Oxysterols receptor LXR-beta 2.4 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100150 104159438 CHEMBL595689 ZINC45351156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158376 Cc1nc2c(cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C22H17F3N2O3S/c1-14-26-21-19(22(23,24)25)10-5-11-20(21)27(14)15-6-3-7-16(12-15)30-17-8-4-9-18(13-17)31(2,28)29/h3-13H,1-2H3 DGPCIFPFGHXRIB-UHFFFAOYSA-N 50306028 2-methyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594757 Oxysterols receptor LXR-beta 111 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306028&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137576 104160389 CHEMBL594757 ZINC45353000 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158377 CCS(=O)(=O)c1cc(F)cc(Oc2cccc(c2)-n2c(C)nc3c(cccc23)C(F)(F)F)c1 InChI=1S/C23H18F4N2O3S/c1-3-33(30,31)19-11-15(24)10-18(13-19)32-17-7-4-6-16(12-17)29-14(2)28-22-20(23(25,26)27)8-5-9-21(22)29/h4-13H,3H2,1-2H3 YJTSPUKQCBSIGP-UHFFFAOYSA-N 50306066 1-(3-(3-(ethylsulfonyl)-5-fluorophenoxy)phenyl)-2-methyl-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594984 Oxysterols receptor LXR-beta 489 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137030 104160427 CHEMBL594984 ZINC45351811 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158378 CC(C)c1nc2c(cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H21F3N2O3S/c1-15(2)23-28-22-20(24(25,26)27)11-6-12-21(22)29(23)16-7-4-8-17(13-16)32-18-9-5-10-19(14-18)33(3,30)31/h4-15H,1-3H3 SWIBRLXHJPCKAR-UHFFFAOYSA-N 50306070 2-isopropyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL603636 Oxysterols receptor LXR-beta 16 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137441 104160431 CHEMBL603636 ZINC45389151 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158379 Cc1nc2c(Cl)cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1 InChI=1S/C21H17ClN2O3S/c1-14-23-21-19(22)10-5-11-20(21)24(14)15-6-3-7-16(12-15)27-17-8-4-9-18(13-17)28(2,25)26/h3-13H,1-2H3 LMLSWHPQUWFGHJ-UHFFFAOYSA-N 50306056 4-chloro-2-methyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-2,3-dihydro-1H-benzo[d]imidazole::CHEMBL594994 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306056&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137713 104160417 CHEMBL594994 ZINC45353048 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158380 CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(nc3c(cccc23)C(F)(F)F)C2CC2)c1 InChI=1S/C24H19F3N2O3S/c1-33(30,31)19-8-3-7-18(14-19)32-17-6-2-5-16(13-17)29-21-10-4-9-20(24(25,26)27)22(21)28-23(29)15-11-12-15/h2-10,13-15H,11-12H2,1H3 NYORNGSRUVZKGU-UHFFFAOYSA-N 50306071 2-cyclopropyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL595011 Oxysterols receptor LXR-beta 93 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137443 104160432 CHEMBL595011 ZINC45339979 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158381 Cc1nc2c(cccc2n1-c1cccc(Oc2cc(F)cc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C22H16F4N2O3S/c1-13-27-21-19(22(24,25)26)7-4-8-20(21)28(13)15-5-3-6-16(11-15)31-17-9-14(23)10-18(12-17)32(2,29)30/h3-12H,1-2H3 SNVDXERLZQEYID-UHFFFAOYSA-N 50306065 1-(3-(3-fluoro-5-(methylsulfonyl)phenoxy)phenyl)-2-methyl-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594983 Oxysterols receptor LXR-beta 315 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137031 104160426 CHEMBL594983 ZINC45351039 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158382 CCc1nc2c(cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C23H19F3N2O3S/c1-3-21-27-22-19(23(24,25)26)11-6-12-20(22)28(21)15-7-4-8-16(13-15)31-17-9-5-10-18(14-17)32(2,29)30/h4-14H,3H2,1-2H3 BUSFVFJRQBYHBW-UHFFFAOYSA-N 50306069 2-ethyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL595936 Oxysterols receptor LXR-beta 22 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306069&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137304 104160430 CHEMBL595936 ZINC45353225 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158383 Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cccc(c2)S(C)(=O)=O)ccc1Cl InChI=1S/C21H16Cl2N2O3S/c1-13-24-21-18(23)7-4-8-19(21)25(13)20-12-15(9-10-17(20)22)28-14-5-3-6-16(11-14)29(2,26)27/h3-12H,1-2H3 RUVMVDAIZHYFPZ-UHFFFAOYSA-N 50306079 4-chloro-1-(2-chloro-5-(3-(methylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL606143 Oxysterols receptor LXR-beta 14 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137979 104160440 CHEMBL606143 ZINC45385516 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158384 CCS(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2c(C)nc3c(Cl)cccc23)c1 InChI=1S/C22H18Cl2N2O3S/c1-3-30(27,28)17-7-4-6-15(12-17)29-16-10-11-18(23)21(13-16)26-14(2)25-22-19(24)8-5-9-20(22)26/h4-13H,3H2,1-2H3 LMTALPSNYCOGGX-UHFFFAOYSA-N 50306080 4-chloro-1-(2-chloro-5-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL595249 Oxysterols receptor LXR-beta 12 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137980 104160441 CHEMBL595249 ZINC45348063 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158385 CCS(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C22H16ClF3N2O3S/c1-2-32(29,30)16-6-3-5-14(11-16)31-15-9-10-18(23)20(12-15)28-13-27-21-17(22(24,25)26)7-4-8-19(21)28/h3-13H,2H2,1H3 INTBHOCJAASBMR-UHFFFAOYSA-N 50306077 1-(2-chloro-5-(3-(ethylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594367 Oxysterols receptor LXR-beta 35 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136418 104160438 CHEMBL594367 ZINC45340253 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158386 CC(C)S(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C23H18ClF3N2O3S/c1-14(2)33(30,31)17-6-3-5-15(11-17)32-16-9-10-19(24)21(12-16)29-13-28-22-18(23(25,26)27)7-4-8-20(22)29/h3-14H,1-2H3 GBFXOJGYUQWRBP-UHFFFAOYSA-N 50306078 1-(2-chloro-5-(3-(isopropylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL595248 Oxysterols receptor LXR-beta 45 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136419 104160439 CHEMBL595248 ZINC45347532 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158387 CC(C)S(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(C)nc3c(cccc23)C(F)(F)F)c1 InChI=1S/C24H21F3N2O3S/c1-15(2)33(30,31)20-10-5-9-19(14-20)32-18-8-4-7-17(13-18)29-16(3)28-23-21(24(25,26)27)11-6-12-22(23)29/h4-15H,1-3H3 ZMLDZMJEIPYMEJ-UHFFFAOYSA-N 50306060 1-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-2-methyl-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594050 Oxysterols receptor LXR-beta 248 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306060&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137029 104160421 CHEMBL594050 ZINC45350388 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158388 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 13 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158389 Cc1nc2c(cccc2n1-c1cccc(Oc2cccc(c2)S(=O)(=O)CCCO)c1)C(F)(F)F InChI=1S/C24H21F3N2O4S/c1-16-28-23-21(24(25,26)27)10-4-11-22(23)29(16)17-6-2-7-18(14-17)33-19-8-3-9-20(15-19)34(31,32)13-5-12-30/h2-4,6-11,14-15,30H,5,12-13H2,1H3 FLQMNHODIBPHAJ-UHFFFAOYSA-N 50306063 3-(3-(3-(2-methyl-4-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)phenoxy)phenylsulfonyl)propan-1-ol::CHEMBL596592 Oxysterols receptor LXR-beta 436 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306063&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137032 104160424 CHEMBL596592 ZINC45355059 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158390 Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cc(F)cc(c2)S(C)(=O)=O)ccc1Cl InChI=1S/C21H15Cl2FN2O3S/c1-12-25-21-18(23)4-3-5-19(21)26(12)20-11-14(6-7-17(20)22)29-15-8-13(24)9-16(10-15)30(2,27)28/h3-11H,1-2H3 SEUOQSBVNSJTTL-UHFFFAOYSA-N 50306082 4-chloro-1-(2-chloro-5-(3-fluoro-5-(methylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL595455 Oxysterols receptor LXR-beta 44 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136012 104160443 CHEMBL595455 ZINC45351097 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158391 CCS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(C)nc3c(Cl)cccc23)c1 InChI=1S/C22H19ClN2O3S/c1-3-29(26,27)19-10-5-9-18(14-19)28-17-8-4-7-16(13-17)25-15(2)24-22-20(23)11-6-12-21(22)25/h4-14H,3H2,1-2H3 XMSRNUPVXCPJHV-UHFFFAOYSA-N 50306059 4-chloro-1-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL593814 Oxysterols receptor LXR-beta 99 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306059&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137714 104160420 CHEMBL593814 ZINC45350352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158392 Cc1nc2c(Cl)cccc2n1-c1cccc(Oc2cccc(c2)S(=O)(=O)C(F)(F)F)c1 InChI=1S/C21H14ClF3N2O3S/c1-13-26-20-18(22)9-4-10-19(20)27(13)14-5-2-6-15(11-14)30-16-7-3-8-17(12-16)31(28,29)21(23,24)25/h2-12H,1H3 LBPQARCLPTVEGQ-UHFFFAOYSA-N 50306064 4-chloro-2-methyl-1-(3-(3-(trifluoromethylsulfonyl)phenoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL596593 Oxysterols receptor LXR-beta 183 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306064&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137845 104160425 CHEMBL596593 ZINC45355062 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158393 Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cccc(c2)S(=O)(=O)C(F)(F)F)ccc1Cl InChI=1S/C21H13Cl2F3N2O3S/c1-12-27-20-17(23)6-3-7-18(20)28(12)19-11-14(8-9-16(19)22)31-13-4-2-5-15(10-13)32(29,30)21(24,25)26/h2-11H,1H3 NKFCIEVAMLCUCO-UHFFFAOYSA-N 50306083 4-chloro-1-(2-chloro-5-(3-(trifluoromethylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL605723 Oxysterols receptor LXR-beta 85 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136014 104160444 CHEMBL605723 ZINC45390529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158394 CC(C)S(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(C)nc3c(Cl)cccc23)c1 InChI=1S/C23H21ClN2O3S/c1-15(2)30(27,28)20-10-5-9-19(14-20)29-18-8-4-7-17(13-18)26-16(3)25-23-21(24)11-6-12-22(23)26/h4-15H,1-3H3 JYNPEZDAIHSJHW-UHFFFAOYSA-N 50306061 4-chloro-1-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL596591 Oxysterols receptor LXR-beta 138 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137715 104160422 CHEMBL596591 ZINC45367460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158395 Cc1nc2ccccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1 InChI=1S/C21H18N2O3S/c1-15-22-20-11-3-4-12-21(20)23(15)16-7-5-8-17(13-16)26-18-9-6-10-19(14-18)27(2,24)25/h3-14H,1-2H3 AVFHESCTYUCKBX-UHFFFAOYSA-N 50306057 2-methyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL595482 Oxysterols receptor LXR-beta 6400 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306057&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137712 104160418 CHEMBL595482 ZINC45350103 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158396 CC(C)c1nc2c(Cl)cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1 InChI=1S/C23H21ClN2O3S/c1-15(2)23-25-22-20(24)11-6-12-21(22)26(23)16-7-4-8-17(13-16)29-18-9-5-10-19(14-18)30(3,27)28/h4-15H,1-3H3 QIEBJBNGMINXIF-UHFFFAOYSA-N 50306075 4-chloro-2-isopropyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL594063 Oxysterols receptor LXR-beta 26 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137168 104160436 CHEMBL594063 ZINC45352262 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158397 CCCS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(C)nc3c(cccc23)C(F)(F)F)c1 InChI=1S/C24H21F3N2O3S/c1-3-13-33(30,31)20-10-5-9-19(15-20)32-18-8-4-7-17(14-18)29-16(2)28-23-21(24(25,26)27)11-6-12-22(23)29/h4-12,14-15H,3,13H2,1-2H3 XDSUZROBCUROQA-UHFFFAOYSA-N 50306062 2-methyl-1-(3-(3-(propylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL604907 Oxysterols receptor LXR-beta 462 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306062&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137033 104160423 CHEMBL604907 ZINC45388182 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158398 CCS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(C)nc3c(cccc23)C(F)(F)F)c1 InChI=1S/C23H19F3N2O3S/c1-3-32(29,30)19-10-5-9-18(14-19)31-17-8-4-7-16(13-17)28-15(2)27-22-20(23(24,25)26)11-6-12-21(22)28/h4-14H,3H2,1-2H3 PZJQTRGWISHVPT-UHFFFAOYSA-N 50306058 1-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL595483 Oxysterols receptor LXR-beta 128 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306058&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136902 104160419 CHEMBL595483 ZINC45350106 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158399 CS(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C21H14ClF3N2O3S/c1-31(28,29)15-5-2-4-13(10-15)30-14-8-9-17(22)19(11-14)27-12-26-20-16(21(23,24)25)6-3-7-18(20)27/h2-12H,1H3 XPWTYUUWBMPVLO-UHFFFAOYSA-N 50306076 1-(2-chloro-5-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594288 Oxysterols receptor LXR-beta 34 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136417 104160437 CHEMBL594288 ZINC45352300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158400 CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(nc3c(cccc23)C(F)(F)F)-c2ccccc2)c1 InChI=1S/C27H19F3N2O3S/c1-36(33,34)22-13-6-12-21(17-22)35-20-11-5-10-19(16-20)32-24-15-7-14-23(27(28,29)30)25(24)31-26(32)18-8-3-2-4-9-18/h2-17H,1H3 XZYFDTYSBRYCCK-UHFFFAOYSA-N 50306073 1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-2-phenyl-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL595224 Oxysterols receptor LXR-beta 4.7 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137442 104160434 CHEMBL595224 ZINC45340013 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50158401 CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(Cc3ccc(F)cc3)nc3c(cccc23)C(F)(F)F)c1 InChI=1S/C28H20F4N2O3S/c1-38(35,36)23-8-3-7-22(17-23)37-21-6-2-5-20(16-21)34-25-10-4-9-24(28(30,31)32)27(25)33-26(34)15-18-11-13-19(29)14-12-18/h2-14,16-17H,15H2,1H3 MFDLTITVUNIPCT-UHFFFAOYSA-N 50306074 2-(4-fluorobenzyl)-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594062 Oxysterols receptor LXR-beta 2.6 ChEMBL 10.1016/j.bmcl.2009.11.099 10.7270/Q2HT2PDZ 20006495 Travins, JM; Bernotas, RC; Kaufman, DH; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137444 104160435 CHEMBL594062 ZINC49756222 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161855 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 140 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161857 CS(=O)(=O)c1cc(Cl)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H16ClF3N2O4S/c1-35(32,33)17-10-14(25)9-16(11-17)34-15-5-2-4-13(8-15)21-18-6-3-7-20(24(26,27)28)22(18)30-12-19(21)23(29)31/h2-12H,1H3,(H2,29,31) OXAVBDIDWNTRGP-UHFFFAOYSA-N 50305494 4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL602446 Oxysterols receptor LXR-beta 10900 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225196 104159855 CHEMBL602446 ZINC49767820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161858 CS(=O)(=O)c1cc(Cl)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H16ClF3N2O4S/c1-35(32,33)17-10-14(25)9-16(11-17)34-15-5-2-4-13(8-15)21-18-6-3-7-20(24(26,27)28)22(18)30-12-19(21)23(29)31/h2-12H,1H3,(H2,29,31) OXAVBDIDWNTRGP-UHFFFAOYSA-N 50305494 4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL602446 Oxysterols receptor LXR-beta 61 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225196 104159855 CHEMBL602446 ZINC49767820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161859 CS(=O)(=O)c1cc(Cl)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H16ClF3N2O4S/c1-35(32,33)17-10-14(25)9-16(11-17)34-15-5-2-4-13(8-15)21-18-6-3-7-20(24(26,27)28)22(18)30-12-19(21)23(29)31/h2-12H,1H3,(H2,29,31) OXAVBDIDWNTRGP-UHFFFAOYSA-N 50305494 4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL602446 Oxysterols receptor LXR-beta 460 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225196 104159855 CHEMBL602446 ZINC49767820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161860 CS(=O)(=O)c1cc(Cl)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H16ClF3N2O4S/c1-35(32,33)17-10-14(25)9-16(11-17)34-15-5-2-4-13(8-15)21-18-6-3-7-20(24(26,27)28)22(18)30-12-19(21)23(29)31/h2-12H,1H3,(H2,29,31) OXAVBDIDWNTRGP-UHFFFAOYSA-N 50305494 4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL602446 Oxysterols receptor LXR-beta 1700 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225196 104159855 CHEMBL602446 ZINC49767820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161863 CCc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H19F3N2O2S/c1-3-20-22(29-21-9-5-8-19(23(21)28-20)24(25,26)27)16-12-10-15(11-13-16)17-6-4-7-18(14-17)32(2,30)31/h4-14H,3H2,1-2H3 FHEOPZZFNWUQEY-UHFFFAOYSA-N 50316094 3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1089232 Oxysterols receptor LXR-beta 18 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316094&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46186945 104150455 CHEMBL1089232 ZINC49066510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161864 CNC(=O)c1cccc(c1)-c1ccc(cc1)-c1nc2cccc(c2nc1C)C(F)(F)F InChI=1S/C24H18F3N3O/c1-14-21(30-20-8-4-7-19(22(20)29-14)24(25,26)27)16-11-9-15(10-12-16)17-5-3-6-18(13-17)23(31)28-2/h3-13H,1-2H3,(H,28,31) YXPHNVAVTJHENT-UHFFFAOYSA-N 50316095 CHEMBL1089231::N-Methyl-4'-[3-methyl-5-(trifluoromethyl)quinoxalin-2-yl]biphenyl-3-carboxamide Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316095&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202905 104150456 CHEMBL1089231 ZINC49126025 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161866 CNS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1nc2cccc(c2nc1C)C(F)(F)F InChI=1S/C23H18F3N3O2S/c1-14-21(29-20-8-4-7-19(22(20)28-14)23(24,25)26)16-11-9-15(10-12-16)17-5-3-6-18(13-17)32(30,31)27-2/h3-13,27H,1-2H3 BBLAZFHAAGNFFZ-UHFFFAOYSA-N 50316096 CHEMBL1090916::N-Methyl-4'-[3-methyl-5-(trifluoromethyl)quinoxalin-2-yl]biphenyl-3-sulfonamide Oxysterols receptor LXR-beta 81 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316096&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202904 104150457 CHEMBL1090916 ZINC49115816 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161870 CCc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H19F3N2O2S/c1-3-20-22(29-21-9-5-8-19(23(21)28-20)24(25,26)27)16-12-10-15(11-13-16)17-6-4-7-18(14-17)32(2,30)31/h4-14H,3H2,1-2H3 FHEOPZZFNWUQEY-UHFFFAOYSA-N 50316094 3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1089232 Oxysterols receptor LXR-beta 3590 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316094&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46186945 104150455 CHEMBL1089232 ZINC49066510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161875 COc1cccc2nc(c(C)nc12)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C23H20N2O3S/c1-15-22(25-20-8-5-9-21(28-2)23(20)24-15)17-12-10-16(11-13-17)18-6-4-7-19(14-18)29(3,26)27/h4-14H,1-3H3 SJSGAVBPKLPYMR-UHFFFAOYSA-N 50316090 5-Methoxy-3-methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]quinoxaline::CHEMBL1093916 Oxysterols receptor LXR-beta 395 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316090&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46203226 104150451 CHEMBL1093916 ZINC49114048 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161876 Cc1nc2c(Cl)cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C22H17ClN2O2S/c1-14-21(25-20-8-4-7-19(23)22(20)24-14)16-11-9-15(10-12-16)17-5-3-6-18(13-17)28(2,26)27/h3-13H,1-2H3 MVLVWBZCSDBJRB-UHFFFAOYSA-N 50316092 5-Chloro-3-methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]quinoxaline::CHEMBL1093499 Oxysterols receptor LXR-beta 34 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316092&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202907 104150453 CHEMBL1093499 ZINC49068963 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161879 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C#N InChI=1S/C23H17N3O2S/c1-15-22(26-21-8-4-6-19(14-24)23(21)25-15)17-11-9-16(10-12-17)18-5-3-7-20(13-18)29(2,27)28/h3-13H,1-2H3 LJUBBBYLSJYHED-UHFFFAOYSA-N 50316091 3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]quinoxaline-5-carbonitrile::CHEMBL1093915 Oxysterols receptor LXR-beta 299 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316091&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46203225 104150452 CHEMBL1093915 ZINC49068672 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161884 CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1cnc2c(cccc2n1)C(F)(F)F InChI=1S/C22H15F3N2O2S/c1-30(28,29)17-5-2-4-16(12-17)14-8-10-15(11-9-14)20-13-26-21-18(22(23,24)25)6-3-7-19(21)27-20/h2-13H,1H3 PDBVPBOUXBRASN-UHFFFAOYSA-N 50316093 2-[3'-(Methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)quinoxaline::CHEMBL1089233 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316093&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202906 104150454 CHEMBL1089233 ZINC49066672 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161886 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 53 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161889 Cc1nc2c(Cl)cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C22H17ClN2O2S/c1-14-21(25-20-8-4-7-19(23)22(20)24-14)16-11-9-15(10-12-16)17-5-3-6-18(13-17)28(2,26)27/h3-13H,1-2H3 MVLVWBZCSDBJRB-UHFFFAOYSA-N 50316092 5-Chloro-3-methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]quinoxaline::CHEMBL1093499 Oxysterols receptor LXR-beta 860 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316092&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202907 104150453 CHEMBL1093499 ZINC49068963 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161890 CCc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H19F3N2O2S/c1-3-20-22(29-21-9-5-8-19(23(21)28-20)24(25,26)27)16-12-10-15(11-13-16)17-6-4-7-18(14-17)32(2,30)31/h4-14H,3H2,1-2H3 FHEOPZZFNWUQEY-UHFFFAOYSA-N 50316094 3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1089232 Oxysterols receptor LXR-beta 2020 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316094&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46186945 104150455 CHEMBL1089232 ZINC49066510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161891 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 170 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161893 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 19 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161894 CS(=O)(=O)c1cc(Cl)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1 InChI=1S/C24H16ClF3N2O4S/c1-35(32,33)17-10-14(25)9-16(11-17)34-15-5-2-4-13(8-15)21-18-6-3-7-20(24(26,27)28)22(18)30-12-19(21)23(29)31/h2-12H,1H3,(H2,29,31) OXAVBDIDWNTRGP-UHFFFAOYSA-N 50305494 4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide::CHEMBL602446 Oxysterols receptor LXR-beta 5100 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46225196 104159855 CHEMBL602446 ZINC49767820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161897 CCS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1nc2cccc(c2nc1C)C(F)(F)F InChI=1S/C24H19F3N2O2S/c1-3-32(30,31)19-7-4-6-18(14-19)16-10-12-17(13-11-16)22-15(2)28-23-20(24(25,26)27)8-5-9-21(23)29-22/h4-14H,3H2,1-2H3 KMWNYUWZKHLPQL-UHFFFAOYSA-N 50316102 2-[3'-(Ethylsulfonyl)biphenyl-4-yl]-3-methyl-5-(trifluoromethyl)-quinoxaline::CHEMBL1093260 Oxysterols receptor LXR-beta 132 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316102&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202903 104150463 CHEMBL1093260 ZINC49069314 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161898 Cc1nc2c(cccc2nc1-c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)17-6-3-5-16(13-17)15-9-11-18(12-10-15)31(2,29)30/h3-13H,1-2H3 ZOAHFZQNTOTYOA-UHFFFAOYSA-N 50316101 3-Methyl-2-[4'-(methylsulfonyl)biphenyl-3-yl]-5-(trifluoromethyl)quinoxaline::CHEMBL1093259 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316101&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202902 104150462 CHEMBL1093259 ZINC49069312 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161899 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1ccccc1S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-19-8-5-7-18(22(19)27-14)23(24,25)26)16-12-10-15(11-13-16)17-6-3-4-9-20(17)31(2,29)30/h3-13H,1-2H3 XRKIRPKDPBHBRD-UHFFFAOYSA-N 50316099 3-Methyl-2-[2'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1089901 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316099&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202579 104150460 CHEMBL1089901 ZINC49112362 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161900 Cc1nc2c(cccc2nc1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-11-5-10-19(22(20)27-14)23(24,25)26)17-8-3-6-15(12-17)16-7-4-9-18(13-16)31(2,29)30/h3-13H,1-2H3 WIRCIXPAVYMAMG-UHFFFAOYSA-N 50316100 3-Methyl-2-[3'-(methylsulfonyl)biphenyl-3-yl]-5-(trifluoromethyl)quinoxaline::CHEMBL1093258 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316100&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202580 104150461 CHEMBL1093258 ZINC49113120 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161901 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-5-3-4-19(22(20)27-14)23(24,25)26)17-8-6-15(7-9-17)16-10-12-18(13-11-16)31(2,29)30/h3-13H,1-2H3 OCOLFJMGVUFGBJ-UHFFFAOYSA-N 50316098 3-Methyl-2-[4'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1089900 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316098&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202578 104150459 CHEMBL1089900 ZINC49067753 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161902 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)16-11-9-15(10-12-16)17-5-3-6-18(13-17)31(2,29)30/h3-13H,1-2H3 YKGVGRQMFLSEFJ-UHFFFAOYSA-N 50316097 3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1093532 Oxysterols receptor LXR-beta 53 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46206336 104150458 CHEMBL1093532 ZINC49071240 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161903 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)16-11-9-15(10-12-16)17-5-3-6-18(13-17)31(2,29)30/h3-13H,1-2H3 YKGVGRQMFLSEFJ-UHFFFAOYSA-N 50316097 3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1093532 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46206336 104150458 CHEMBL1093532 ZINC49071240 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161904 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)16-11-9-15(10-12-16)17-5-3-6-18(13-17)31(2,29)30/h3-13H,1-2H3 YKGVGRQMFLSEFJ-UHFFFAOYSA-N 50316097 3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1093532 Oxysterols receptor LXR-beta 1700 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46206336 104150458 CHEMBL1093532 ZINC49071240 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161905 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)16-11-9-15(10-12-16)17-5-3-6-18(13-17)31(2,29)30/h3-13H,1-2H3 YKGVGRQMFLSEFJ-UHFFFAOYSA-N 50316097 3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1093532 Oxysterols receptor LXR-beta 580 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46206336 104150458 CHEMBL1093532 ZINC49071240 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161906 Cc1nc2c(cccc2nc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H17F3N2O2S/c1-14-21(28-20-8-4-7-19(22(20)27-14)23(24,25)26)16-11-9-15(10-12-16)17-5-3-6-18(13-17)31(2,29)30/h3-13H,1-2H3 YKGVGRQMFLSEFJ-UHFFFAOYSA-N 50316097 3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline::CHEMBL1093532 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46206336 104150458 CHEMBL1093532 ZINC49071240 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50161907 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 9 ChEMBL 10.1021/jm100034x 10.7270/Q29W0FN8 20350005 Hu, B; Unwalla, RJ; Goljer, I; Jetter, JW; Quinet, EM; Berrodin, TJ; Basso, MD; Feingold, IB; Nilsson, AG; Wilhelmsson, A; Evans, MJ; Wrobel, JE Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50164209 CN(Cc1ccc(cc1)C(O)=O)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)nc1C(F)(F)F InChI=1S/C28H22Cl2F3N3O4/c1-36(13-15-5-7-17(8-6-15)27(37)38)21-11-12-22(34-26(21)28(31,32)33)39-14-18-24(35-40-25(18)16-9-10-16)23-19(29)3-2-4-20(23)30/h2-8,11-12,16H,9-10,13-14H2,1H3,(H,37,38) KNWXWQGSCZVUGX-UHFFFAOYSA-N 50323533 4-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid::CHEMBL1209173 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2010.06.084 10.7270/Q21V5F52 20638278 Abel, U; Schluter, T; Schulz, A; Hambruch, E; Steeneck, C; Hornberger, M; Hoffmann, T; Perovic-Ottstadt, S; Kinzel, O; Burnet, M; Deuschle, U; Kremoser, C Phenex Pharmaceuticals AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323533&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44476535 117644854 CHEMBL1209173 ZINC58559121 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50164212 CN(Cc1cccc(c1)C(O)=O)c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)nc1C(F)(F)F InChI=1S/C28H22Cl2F3N3O4/c1-36(13-15-4-2-5-17(12-15)27(37)38)21-10-11-22(34-26(21)28(31,32)33)39-14-18-24(35-40-25(18)16-8-9-16)23-19(29)6-3-7-20(23)30/h2-7,10-12,16H,8-9,13-14H2,1H3,(H,37,38) ZXYUQEKGVUJPEO-UHFFFAOYSA-N 50323530 3-(((6-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid::CHEMBL1209170 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2010.06.084 10.7270/Q21V5F52 20638278 Abel, U; Schluter, T; Schulz, A; Hambruch, E; Steeneck, C; Hornberger, M; Hoffmann, T; Perovic-Ottstadt, S; Kinzel, O; Burnet, M; Deuschle, U; Kremoser, C Phenex Pharmaceuticals AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323530&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49862248 117644851 CHEMBL1209170 ZINC58568344 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206135 CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO4S/c1-2-4-14-17(7-6-15-20(14)31-27-21(15)22(24,25)26)30-9-3-10-32-18-8-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) TZBRFAASYWFUGK-UHFFFAOYSA-N 50126018 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid::CHEMBL23296::{3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid::{3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)sulfanyl]phenyl}acetic acid Oxysterols receptor LXR-beta 1080 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O90 3IPS 9935197 104018161 CHEMBL23296 2688 ZINC03834054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206136 CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO4S/c1-2-4-14-17(7-6-15-20(14)31-27-21(15)22(24,25)26)30-9-3-10-32-18-8-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) TZBRFAASYWFUGK-UHFFFAOYSA-N 50126018 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid::CHEMBL23296::{3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid::{3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)sulfanyl]phenyl}acetic acid Oxysterols receptor LXR-beta 16 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O90 3IPS 9935197 104018161 CHEMBL23296 2688 ZINC03834054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206137 CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)C(F)(F)F InChI=1S/C22H21ClF3NO4S/c1-2-4-14-17(7-6-15-20(14)31-27-21(15)22(24,25)26)30-9-3-10-32-18-8-5-13(11-16(18)23)12-19(28)29/h5-8,11H,2-4,9-10,12H2,1H3,(H,28,29) TZBRFAASYWFUGK-UHFFFAOYSA-N 50126018 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid::CHEMBL23296::{3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid::{3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)sulfanyl]phenyl}acetic acid Oxysterols receptor LXR-beta 25 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O90 3IPS 9935197 104018161 CHEMBL23296 2688 ZINC03834054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206139 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H43NO4/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(36)19-25(21)31)29(38)35-30(39)34(4)18-6-16-32(2)26-20-24(37)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,36-37H,5-6,9-10,13-18H2,1-4H3,(H,35,38,39)/t27-,28-,31-,32-,33+,34?/m1/s1 ASTLYMNMTDERKI-IMUKZWIGSA-N 50167697 (4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::(4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL365544 Oxysterols receptor LXR-beta <3 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400748 104052913 CHEMBL365544 ZINC28520935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206140 CC1(CCCC2(C)C1CCc1ccc(O)cc21)C(=O)OC(=O)C1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H42O5/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(35)19-25(21)31)29(37)39-30(38)34(4)18-6-16-32(2)26-20-24(36)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,35-36H,5-6,9-10,13-18H2,1-4H3/t27-,28?,31-,32?,33?,34?/m1/s1 CXSWMXMKWWOTPK-PZXRDPTESA-N 50167698 13-hydroxy-2,6-dimethyl-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 13-hydroxy-2,6-dimethyltricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL555373 Oxysterols receptor LXR-beta 1 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167698&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44399795 104052914 CHEMBL555373 ZINC38149324 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206141 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H43NO4/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(36)19-25(21)31)29(38)35-30(39)34(4)18-6-16-32(2)26-20-24(37)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,36-37H,5-6,9-10,13-18H2,1-4H3,(H,35,38,39)/t27-,28-,31-,32-,33+,34?/m1/s1 ASTLYMNMTDERKI-IMUKZWIGSA-N 50167697 (4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::(4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL365544 Oxysterols receptor LXR-beta 1 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400748 104052913 CHEMBL365544 ZINC28520935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206142 CC(=O)Oc1ccc2CC[C@H]3C(C)(CCC[C@]3(C)c2c1)C(=O)OC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(OC(C)=O)cc21 InChI=1S/C38H46O7/c1-23(39)43-27-13-9-25-11-15-31-35(3,29(25)21-27)17-7-19-37(31,5)33(41)45-34(42)38(6)20-8-18-36(4)30-22-28(44-24(2)40)14-10-26(30)12-16-32(36)38/h9-10,13-14,21-22,31-32H,7-8,11-12,15-20H2,1-6H3/t31-,32-,35-,36-,37+,38?/m1/s1 OUJQRQRBNRGQTC-PWAHEJKMSA-N 50167694 2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-triene-6-carboxylic anhydride::2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL191965 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400646 104052910 CHEMBL191965 ZINC38149326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206143 CC1(CCCC2(C)C1CCc1ccc(O)cc21)C(=O)OC(=O)C1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H42O5/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(35)19-25(21)31)29(37)39-30(38)34(4)18-6-16-32(2)26-20-24(36)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,35-36H,5-6,9-10,13-18H2,1-4H3/t27-,28?,31-,32?,33?,34?/m1/s1 CXSWMXMKWWOTPK-PZXRDPTESA-N 50167698 13-hydroxy-2,6-dimethyl-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 13-hydroxy-2,6-dimethyltricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL555373 Oxysterols receptor LXR-beta 1 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167698&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44399795 104052914 CHEMBL555373 ZINC38149324 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206144 CC(=O)Oc1ccc2CC[C@H]3C(C)(CCC[C@]3(C)c2c1)C(=O)OC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(OC(C)=O)cc21 InChI=1S/C38H46O7/c1-23(39)43-27-13-9-25-11-15-31-35(3,29(25)21-27)17-7-19-37(31,5)33(41)45-34(42)38(6)20-8-18-36(4)30-22-28(44-24(2)40)14-10-26(30)12-16-32(36)38/h9-10,13-14,21-22,31-32H,7-8,11-12,15-20H2,1-6H3/t31-,32-,35-,36-,37+,38?/m1/s1 OUJQRQRBNRGQTC-PWAHEJKMSA-N 50167694 2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-triene-6-carboxylic anhydride::2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL191965 Oxysterols receptor LXR-beta 10 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400646 104052910 CHEMBL191965 ZINC38149326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206145 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(OC(=O)[C@@]3(C)CCC[C@@]4(C)[C@H]3CCc3ccc(O)cc43)cc21)C(O)=O InChI=1S/C34H42O5/c1-31-16-6-18-34(4,28(31)14-10-21-7-11-23(35)19-25(21)31)30(38)39-24-12-8-22-9-13-27-32(2,26(22)20-24)15-5-17-33(27,3)29(36)37/h7-8,11-12,19-20,27-28,35H,5-6,9-10,13-18H2,1-4H3,(H,36,37)/t27-,28-,31-,32-,33?,34+/m1/s1 ZSYSAEZLDANPLF-ZXKBSOPMSA-N 50167695 13-[13-hydroxy-2,6-dimethyl-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-trien-6-ylcarbonyloxy]-2,6-dimethyl-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-triene-6-carboxylic acid::CHEMBL364012 Oxysterols receptor LXR-beta 29 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167695&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400184 104052911 CHEMBL364012 ZINC28475554 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206147 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(O)=O InChI=1S/C17H22O3/c1-16-8-3-9-17(2,15(19)20)14(16)7-5-11-4-6-12(18)10-13(11)16/h4,6,10,14,18H,3,5,7-9H2,1-2H3,(H,19,20)/t14-,16-,17+/m1/s1 VJILEYKNALCDDV-OIISXLGYSA-N 50167696 (1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydroxy-1,4a-dimethylphenanthrene-1-carboxylic acid::(1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid::12-hydroxypodocarpa-8,11,13-trien-16-oic acid::CHEMBL421115::Podocarpic acid Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167696&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 93017 104052912 8277 CHEMBL421115 C09171 ZINC03947415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206149 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)CC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C35H44O4/c1-32-15-5-17-34(3,28(32)13-9-22-7-11-24(36)19-26(22)32)30(38)21-31(39)35(4)18-6-16-33(2)27-20-25(37)12-8-23(27)10-14-29(33)35/h7-8,11-12,19-20,28-29,36-37H,5-6,9-10,13-18,21H2,1-4H3/t28-,29-,32-,33-,34+,35?/m1/s1 QDOPVBPHOQDBJS-JKQUCLBSSA-N 50167699 1-((9R,10S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-3-((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-propane-1,3-dione::CHEMBL192837 Oxysterols receptor LXR-beta 163 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167699&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400273 104052915 CHEMBL192837 ZINC28473821 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206151 C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(O)=O InChI=1S/C17H22O3/c1-16-8-3-9-17(2,15(19)20)14(16)7-5-11-4-6-12(18)10-13(11)16/h4,6,10,14,18H,3,5,7-9H2,1-2H3,(H,19,20)/t14-,16-,17+/m1/s1 VJILEYKNALCDDV-OIISXLGYSA-N 50167696 (1S,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-6-hydroxy-1,4a-dimethylphenanthrene-1-carboxylic acid::(1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid::12-hydroxypodocarpa-8,11,13-trien-16-oic acid::CHEMBL421115::Podocarpic acid Oxysterols receptor LXR-beta >50000 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167696&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 93017 104052912 8277 CHEMBL421115 C09171 ZINC03947415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206156 CC1(COC(=O)[C@@]2(C)CCC[C@@]3(C)[C@H]2CCc2ccc(O)cc32)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H44O4/c1-31(15-5-16-32(2)26-19-24(35)11-7-22(26)9-13-28(31)32)21-38-30(37)34(4)18-6-17-33(3)27-20-25(36)12-8-23(27)10-14-29(33)34/h7-8,11-12,19-20,28-29,35-36H,5-6,9-10,13-18,21H2,1-4H3/t28-,29+,31?,32+,33+,34-/m0/s1 SYOKLRCUKUPRMN-ZFHJGKNLSA-N 50167700 (1S,4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid (4aR,9S)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-ylmethyl ester::CHEMBL195184 Oxysterols receptor LXR-beta 12 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167700&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400680 104052916 CHEMBL195184 ZINC28521821 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206159 CC(C)CC[C@@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1 RZPAXNJLEKLXNO-GFKLAVDKSA-N 20177 (1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::22(R)-hydroxycholesterol::CHEMBL422904 Oxysterols receptor LXR-beta 15000 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20177&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search HC9 3N9Z,3MZS,3L0J 167685 49688252 67237 CHEMBL422904 2742 C05502 ZINC04096816 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206160 CC(=O)Oc1ccc2CC[C@H]3C(C)(CCC[C@]3(C)c2c1)C(=O)OC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(OC(C)=O)cc21 InChI=1S/C38H46O7/c1-23(39)43-27-13-9-25-11-15-31-35(3,29(25)21-27)17-7-19-37(31,5)33(41)45-34(42)38(6)20-8-18-36(4)30-22-28(44-24(2)40)14-10-26(30)12-16-32(36)38/h9-10,13-14,21-22,31-32H,7-8,11-12,15-20H2,1-6H3/t31-,32-,35-,36-,37+,38?/m1/s1 OUJQRQRBNRGQTC-PWAHEJKMSA-N 50167694 2,6-dimethyl-13-methylcarbonyloxy-(2S)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(14),10,12-triene-6-carboxylic anhydride::2,6-dimethyl-13-methylcarbonyloxy-(2S,6S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 2,6-dimethyl-13-methylcarbonyloxy-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL191965 Oxysterols receptor LXR-beta 2 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400646 104052910 CHEMBL191965 ZINC38149326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206161 CC1(CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21)C(=O)NC(=O)[C@@]1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H43NO4/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(36)19-25(21)31)29(38)35-30(39)34(4)18-6-16-32(2)26-20-24(37)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,36-37H,5-6,9-10,13-18H2,1-4H3,(H,35,38,39)/t27-,28-,31-,32-,33+,34?/m1/s1 ASTLYMNMTDERKI-IMUKZWIGSA-N 50167697 (4aR,9S)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::(4aS,10aR)-6-Hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1S,4aS,10aR)-6-hydroxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carbonyl)-amide::CHEMBL365544 Oxysterols receptor LXR-beta 1 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44400748 104052913 CHEMBL365544 ZINC28520935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50206162 CC1(CCCC2(C)C1CCc1ccc(O)cc21)C(=O)OC(=O)C1(C)CCC[C@@]2(C)[C@H]1CCc1ccc(O)cc21 InChI=1S/C34H42O5/c1-31-15-5-17-33(3,27(31)13-9-21-7-11-23(35)19-25(21)31)29(37)39-30(38)34(4)18-6-16-32(2)26-20-24(36)12-8-22(26)10-14-28(32)34/h7-8,11-12,19-20,27-28,35-36H,5-6,9-10,13-18H2,1-4H3/t27-,28?,31-,32?,33?,34?/m1/s1 CXSWMXMKWWOTPK-PZXRDPTESA-N 50167698 13-hydroxy-2,6-dimethyl-(2S,7R)-tricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic 13-hydroxy-2,6-dimethyltricyclo[8.4.0.02,7]tetradeca-1(10),11,13-triene-6-carboxylic anhydride::CHEMBL555373 Oxysterols receptor LXR-beta <3 ChEMBL 10.1016/j.bmcl.2005.03.100 10.7270/Q29G5NM2 15911262 Singh, SB; Ondeyka, JG; Liu, W; Chen, S; Chen, TS; Li, X; Bouffard, A; Dropinski, J; Jones, AB; McCormick, S; Hayes, N; Wang, J; Sharma, N; Macnaul, K; Hernandez, M; Chao, YS; Baffic, J; Lam, MH; Burton, C; Sparrow, CP; Menke, JG Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167698&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44399795 104052914 CHEMBL555373 ZINC38149324 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219735 CN(C(=O)c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H13F6NO2/c1-24(14(25)11-5-3-2-4-6-11)13-9-7-12(8-10-13)15(26,16(18,19)20)17(21,22)23/h2-10,26H,1H3 NZMKNKKURNJCLW-UHFFFAOYSA-N 50179863 CHEMBL379225::N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzamide Oxysterols receptor LXR-beta 180 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179863&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5188108 104065010 CHEMBL379225 ZINC03639394 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219736 CN1c2ccc(O)cc2C(=C)c2ccccc2C1=O InChI=1S/C16H13NO2/c1-10-12-5-3-4-6-13(12)16(19)17(2)15-8-7-11(18)9-14(10)15/h3-9,18H,1H2,2H3 VGQGXKVPVNOLEN-UHFFFAOYSA-N 50396601 CHEMBL2171902 Oxysterols receptor LXR-beta 11000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396601&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71458918 163345625 CHEMBL2171902 ZINC95557279 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219737 CCc1ccc2N(C)C(=O)c3cc(ccc3C(=C)c2c1)-c1cccc(c1)C(O)=O InChI=1S/C25H21NO3/c1-4-16-8-11-23-21(12-16)15(2)20-10-9-18(14-22(20)24(27)26(23)3)17-6-5-7-19(13-17)25(28)29/h5-14H,2,4H2,1,3H3,(H,28,29) QQYRQGGQEDJICW-UHFFFAOYSA-N 50396608 CHEMBL2171917 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396608&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71460729 163345632 CHEMBL2171917 ZINC95554944 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219738 CN1c2ccccc2C(=C)c2ccccc2C1=O InChI=1S/C16H13NO/c1-11-12-7-3-4-9-14(12)16(18)17(2)15-10-6-5-8-13(11)15/h3-10H,1H2,2H3 CZQFCTUZSYAAGX-UHFFFAOYSA-N 50396588 CHEMBL2171910 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396588&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 21050637 163345612 CHEMBL2171910 ZINC95555254 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50224255 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C17H15F6NO3S/c1-2-24(28(26,27)14-6-4-3-5-7-14)13-10-8-12(9-11-13)15(25,16(18,19)20)17(21,22)23/h3-11,25H,2H2,1H3 IVNRPSKTRKQRGY-UHFFFAOYSA-N 50426729 CHEMBL2326845 Oxysterols receptor LXR-beta 10 ChEMBL 10.1016/j.bmcl.2012.11.012 10.7270/Q2P270GF 23246324 Jun, HJ; Hoang, MH; Yeo, SK; Jia, Y; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50426729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50426729&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 20704150 164155604 CHEMBL2326845 ZINC95581430 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213178 CN(C)Cc1nc2c(cccn2c1-c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H22F3N3O2S/c1-29(2)15-21-22(30-12-6-11-20(23(30)28-21)24(25,26)27)18-9-4-7-16(13-18)17-8-5-10-19(14-17)33(3,31)32/h4-14H,15H2,1-3H3 XUYDVGGQPPZCPF-UHFFFAOYSA-N 50306043 CHEMBL604703::N,N-dimethyl-1-(3-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)methanamine Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306043&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46226367 104160404 CHEMBL604703 ZINC45389858 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213181 CCc1nc2c(cccn2c1-c1cccc(Cc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H21F3N2O2S/c1-3-21-22(29-12-6-11-20(23(29)28-21)24(25,26)27)18-9-4-7-16(14-18)13-17-8-5-10-19(15-17)32(2,30)31/h4-12,14-15H,3,13H2,1-2H3 YVLZLCWGCDOOAT-UHFFFAOYSA-N 50306022 2-ethyl-3-(3-(3-(methylsulfonyl)benzyl)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL606756 Oxysterols receptor LXR-beta 3200 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306022&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46226434 104160383 CHEMBL606756 ZINC45387779 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213182 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(nc3c(cccn23)C(F)(F)F)-n2ccnc2)c1 InChI=1S/C24H17F3N4O3S/c1-35(32,33)19-8-3-7-18(14-19)34-17-6-2-5-16(13-17)21-23(30-12-10-28-15-30)29-22-20(24(25,26)27)9-4-11-31(21)22/h2-15H,1H3 GRHBEGZXUDYQLG-UHFFFAOYSA-N 50378594 CHEMBL608531 Oxysterols receptor LXR-beta 1700 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378594&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877578 160857677 CHEMBL608531 ZINC49109465 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213183 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(CN3CCSC3)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C25H22F3N3O3S2/c1-36(32,33)20-8-3-7-19(14-20)34-18-6-2-5-17(13-18)23-22(15-30-11-12-35-16-30)29-24-21(25(26,27)28)9-4-10-31(23)24/h2-10,13-14H,11-12,15-16H2,1H3 CBDKGOMYQLDSHF-UHFFFAOYSA-N 50378593 CHEMBL612007 Oxysterols receptor LXR-beta 170 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378593&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877577 160857676 CHEMBL612007 ZINC43206220 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213184 CC(C)c1nc2c(cccn2c1-c1cccc(OCc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C25H23F3N2O3S/c1-16(2)22-23(30-12-6-11-21(24(30)29-22)25(26,27)28)18-8-5-9-19(14-18)33-15-17-7-4-10-20(13-17)34(3,31)32/h4-14,16H,15H2,1-3H3 DMUPDMHGBPGHOY-UHFFFAOYSA-N 50306024 2-isopropyl-3-(3-(3-(methylsulfonyl)benzyloxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL596381 Oxysterols receptor LXR-beta 6500 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306024&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136346 104160385 CHEMBL596381 ZINC45355601 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213185 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(CN3CCCCC3)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C27H26F3N3O3S/c1-37(34,35)22-11-6-10-21(17-22)36-20-9-5-8-19(16-20)25-24(18-32-13-3-2-4-14-32)31-26-23(27(28,29)30)12-7-15-33(25)26/h5-12,15-17H,2-4,13-14,18H2,1H3 BSNQJTLXVANSQQ-UHFFFAOYSA-N 50378592 CHEMBL612006 Oxysterols receptor LXR-beta 920 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378592&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877576 160857675 CHEMBL612006 ZINC49785723 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213186 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 13 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213187 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C28H21F3N2O3S/c1-37(34,35)23-13-6-12-22(18-23)36-21-11-5-10-20(17-21)26-25(16-19-8-3-2-4-9-19)32-27-24(28(29,30)31)14-7-15-33(26)27/h2-15,17-18H,16H2,1H3 JQOXVKXWQCMPRP-UHFFFAOYSA-N 50378590 CHEMBL611735 Oxysterols receptor LXR-beta 144 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378590&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42641405 160857673 CHEMBL611735 ZINC49775306 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213188 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(nc3c(cccn23)C(F)(F)F)-c2ccccc2)c1 InChI=1S/C27H19F3N2O3S/c1-36(33,34)22-13-6-12-21(17-22)35-20-11-5-10-19(16-20)25-24(18-8-3-2-4-9-18)31-26-23(27(28,29)30)14-7-15-32(25)26/h2-17H,1H3 GUEIWDLJEBMFMQ-UHFFFAOYSA-N 50378589 CHEMBL611734 Oxysterols receptor LXR-beta 1110 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378589&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136969 160857672 CHEMBL611734 ZINC49032179 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213190 Cc1nc2c(cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C22H17F3N2O3S/c1-14-26-21-19(22(23,24)25)10-5-11-20(21)27(14)15-6-3-7-16(12-15)30-17-8-4-9-18(13-17)31(2,28)29/h3-13H,1-2H3 DGPCIFPFGHXRIB-UHFFFAOYSA-N 50306028 2-methyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594757 Oxysterols receptor LXR-beta 128 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306028&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137576 104160389 CHEMBL594757 ZINC45353000 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213191 CC(C)(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C25H23F3N2O3S/c1-24(2,3)22-21(30-13-7-12-20(23(30)29-22)25(26,27)28)16-8-5-9-17(14-16)33-18-10-6-11-19(15-18)34(4,31)32/h5-15H,1-4H3 LAHPLBHKJGGIEF-UHFFFAOYSA-N 50378588 CHEMBL611467 Oxysterols receptor LXR-beta 2180 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378588&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136717 160857671 CHEMBL611467 ZINC49031157 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213193 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H18F3NO3S/c1-15-14-28-23-20(10-5-11-21(23)24(25,26)27)22(15)16-6-3-7-17(12-16)31-18-8-4-9-19(13-18)32(2,29)30/h3-14H,1-2H3 ZDUOYBOFMKORCT-UHFFFAOYSA-N 50305077 3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595689 Oxysterols receptor LXR-beta 2.4 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100150 104159438 CHEMBL595689 ZINC45351156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213194 CC(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H21F3N2O3S/c1-15(2)21-22(29-12-6-11-20(23(29)28-21)24(25,26)27)16-7-4-8-17(13-16)32-18-9-5-10-19(14-18)33(3,30)31/h4-15H,1-3H3 QQDXQGDFJZPVRX-UHFFFAOYSA-N 50378587 CHEMBL611466 Oxysterols receptor LXR-beta 1860 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378587&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877573 160857670 CHEMBL611466 ZINC49792515 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213195 CCc1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C23H19F3N2O3S/c1-3-20-21(28-12-6-11-19(22(28)27-20)23(24,25)26)15-7-4-8-16(13-15)31-17-9-5-10-18(14-17)32(2,29)30/h4-14H,3H2,1-2H3 WZXCTCJIJVBAOX-UHFFFAOYSA-N 50378586 CHEMBL611465 Oxysterols receptor LXR-beta 1220 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378586&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137636 160857669 CHEMBL611465 ZINC49052431 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213196 CC(C)S(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C24H21F3N2O3S/c1-15(2)33(30,31)20-10-5-9-19(14-20)32-18-8-4-7-17(13-18)22-16(3)28-23-21(24(25,26)27)11-6-12-29(22)23/h4-15H,1-3H3 TXKFTWAELLNECY-UHFFFAOYSA-N 50306031 3-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL596357 Oxysterols receptor LXR-beta 4100 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306031&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46226318 104160392 CHEMBL596357 ZINC45364755 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213197 Cc1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(=O)(=O)CCCO)c1)C(F)(F)F InChI=1S/C24H21F3N2O4S/c1-16-22(29-11-4-10-21(23(29)28-16)24(25,26)27)17-6-2-7-18(14-17)33-19-8-3-9-20(15-19)34(31,32)13-5-12-30/h2-4,6-11,14-15,30H,5,12-13H2,1H3 BEGFQLFGEWZPNM-UHFFFAOYSA-N 50306032 3-(3-(3-(2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)phenoxy)phenylsulfonyl)propan-1-ol::CHEMBL604701 Oxysterols receptor LXR-beta 6000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137503 104160393 CHEMBL604701 ZINC45389854 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213198 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 135 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213199 COc1ccc(CN(C)S(=O)(=O)c2cccc(Oc3cccc(c3)-c3c(nc4c(Cl)cccn34)C(C)C)c2)cc1 InChI=1S/C31H30ClN3O4S/c1-21(2)29-30(35-17-7-12-28(32)31(35)33-29)23-8-5-9-25(18-23)39-26-10-6-11-27(19-26)40(36,37)34(3)20-22-13-15-24(38-4)16-14-22/h5-19,21H,20H2,1-4H3 IAVNBGWOUPTSOV-UHFFFAOYSA-N 50306046 3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-(4-methoxybenzyl)-N-methylbenzenesulfonamide::CHEMBL595915 Oxysterols receptor LXR-beta 71 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306046&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136075 104160407 CHEMBL595915 ZINC49757424 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213200 CNS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(nc3c(Cl)cccn23)C(C)C)c1 InChI=1S/C23H22ClN3O3S/c1-15(2)21-22(27-12-6-11-20(24)23(27)26-21)16-7-4-8-17(13-16)30-18-9-5-10-19(14-18)31(28,29)25-3/h4-15,25H,1-3H3 ZLCICKWEGSYHOX-UHFFFAOYSA-N 50306020 3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-methylbenzenesulfonamide::CHEMBL595917 Oxysterols receptor LXR-beta 1610 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306020&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136213 104160381 CHEMBL595917 ZINC45349647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213201 CC(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(CS(C)(=O)=O)c2)c1)C(F)(F)F InChI=1S/C25H23F3N2O3S/c1-16(2)22-23(30-12-6-11-21(24(30)29-22)25(26,27)28)18-8-5-10-20(14-18)33-19-9-4-7-17(13-19)15-34(3,31)32/h4-14,16H,15H2,1-3H3 ZEAJIAJGUMPEMM-UHFFFAOYSA-N 50306021 2-isopropyl-3-(3-(3-(methylsulfonylmethyl)phenoxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL604797 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306021&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137369 104160382 CHEMBL604797 ZINC45387580 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213202 COc1ccc(CN(C)S(=O)(=O)c2cccc(Oc3cccc(c3)-c3c(nc4c(Cl)cccn34)C(C)C)c2)cc1 InChI=1S/C31H30ClN3O4S/c1-21(2)29-30(35-17-7-12-28(32)31(35)33-29)23-8-5-9-25(18-23)39-26-10-6-11-27(19-26)40(36,37)34(3)20-22-13-15-24(38-4)16-14-22/h5-19,21H,20H2,1-4H3 IAVNBGWOUPTSOV-UHFFFAOYSA-N 50306046 3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-(4-methoxybenzyl)-N-methylbenzenesulfonamide::CHEMBL595915 Oxysterols receptor LXR-beta 930 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306046&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136075 104160407 CHEMBL595915 ZINC49757424 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213203 CNS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(nc3c(Cl)cccn23)C(C)C)c1 InChI=1S/C23H22ClN3O3S/c1-15(2)21-22(27-12-6-11-20(24)23(27)26-21)16-7-4-8-17(13-16)30-18-9-5-10-19(14-18)31(28,29)25-3/h4-15,25H,1-3H3 ZLCICKWEGSYHOX-UHFFFAOYSA-N 50306020 3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-methylbenzenesulfonamide::CHEMBL595917 Oxysterols receptor LXR-beta 239 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306020&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136213 104160381 CHEMBL595917 ZINC45349647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213204 CC(C)c1nc2c(Cl)cccn2c1-c1cccc(Oc2cccc(c2)S(N)(=O)=O)c1 InChI=1S/C22H20ClN3O3S/c1-14(2)20-21(26-11-5-10-19(23)22(26)25-20)15-6-3-7-16(12-15)29-17-8-4-9-18(13-17)30(24,27)28/h3-14H,1-2H3,(H2,24,27,28) CBHCJQLRHMPCIO-UHFFFAOYSA-N 50306047 3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)benzenesulfonamide::CHEMBL605107 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306047&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44135945 104160408 CHEMBL605107 ZINC45392689 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213205 CCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C23H19F3N2O3S/c1-3-32(29,30)19-10-5-9-18(14-19)31-17-8-4-7-16(13-17)21-15(2)27-22-20(23(24,25)26)11-6-12-28(21)22/h4-14H,3H2,1-2H3 XBWKFFVZKTYRJE-UHFFFAOYSA-N 50306030 3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL595937 Oxysterols receptor LXR-beta 2280 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137367 104160391 CHEMBL595937 ZINC45349701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213206 Cc1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C22H17F3N2O3S/c1-14-20(27-11-5-10-19(21(27)26-14)22(23,24)25)15-6-3-7-16(12-15)30-17-8-4-9-18(13-17)31(2,28)29/h3-13H,1-2H3 FSSRGWRMAQZYCP-UHFFFAOYSA-N 50306029 2-methyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL605314 Oxysterols receptor LXR-beta 2540 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306029&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137366 104160390 CHEMBL605314 ZINC45389924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213207 CC(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C#N InChI=1S/C24H21N3O3S/c1-16(2)22-23(27-12-6-8-18(15-25)24(27)26-22)17-7-4-9-19(13-17)30-20-10-5-11-21(14-20)31(3,28)29/h4-14,16H,1-3H3 VQRTZDLCUUUFRV-UHFFFAOYSA-N 50306042 2-isopropyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)imidazo[1,2-a]pyridine-8-carbonitrile::CHEMBL596157 Oxysterols receptor LXR-beta 3900 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306042&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136604 104160403 CHEMBL596157 ZINC45355568 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213208 CC(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(=O)(=O)C(F)(F)F)c1)C(F)(F)F InChI=1S/C24H18F6N2O3S/c1-14(2)20-21(32-11-5-10-19(22(32)31-20)23(25,26)27)15-6-3-7-16(12-15)35-17-8-4-9-18(13-17)36(33,34)24(28,29)30/h3-14H,1-2H3 QXYBKHFLOLGOQF-UHFFFAOYSA-N 50306045 2-isopropyl-8-(trifluoromethyl)-3-(3-(3-(trifluoromethylsulfonyl)phenoxy)phenyl)imidazo[1,2-a]pyridine::CHEMBL596158 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306045&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136351 104160406 CHEMBL596158 ZINC49762043 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213209 CC(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C#N InChI=1S/C24H21N3O3S/c1-16(2)22-23(27-12-6-8-18(15-25)24(27)26-22)17-7-4-9-19(13-17)30-20-10-5-11-21(14-20)31(3,28)29/h4-14,16H,1-3H3 VQRTZDLCUUUFRV-UHFFFAOYSA-N 50306042 2-isopropyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)imidazo[1,2-a]pyridine-8-carbonitrile::CHEMBL596157 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306042&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136604 104160403 CHEMBL596157 ZINC45355568 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213211 CC(C)c1nc2c(Cl)cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1 InChI=1S/C23H21ClN2O3S/c1-15(2)21-22(26-12-6-11-20(24)23(26)25-21)16-7-4-8-17(13-16)29-18-9-5-10-19(14-18)30(3,27)28/h4-15H,1-3H3 NKFDLBSCCAQKKW-UHFFFAOYSA-N 50306041 8-chloro-2-isopropyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)imidazo[1,2-a]pyridine::CHEMBL603956 Oxysterols receptor LXR-beta 304 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306041&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136477 104160402 CHEMBL603956 ZINC45386954 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213213 CC(C)c1nc2c(Cl)cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1 InChI=1S/C23H21ClN2O3S/c1-15(2)21-22(26-12-6-11-20(24)23(26)25-21)16-7-4-8-17(13-16)29-18-9-5-10-19(14-18)30(3,27)28/h4-15H,1-3H3 NKFDLBSCCAQKKW-UHFFFAOYSA-N 50306041 8-chloro-2-isopropyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)imidazo[1,2-a]pyridine::CHEMBL603956 Oxysterols receptor LXR-beta 1660 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306041&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136477 104160402 CHEMBL603956 ZINC45386954 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213214 CCS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C23H19F3N2O3S/c1-3-32(29,30)19-10-5-9-18(14-19)31-17-8-4-7-16(13-17)21-15(2)27-22-20(23(24,25)26)11-6-12-28(21)22/h4-14H,3H2,1-2H3 XBWKFFVZKTYRJE-UHFFFAOYSA-N 50306030 3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL595937 Oxysterols receptor LXR-beta 561 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137367 104160391 CHEMBL595937 ZINC45349701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213215 Cc1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C22H17F3N2O3S/c1-14-20(27-11-5-10-19(21(27)26-14)22(23,24)25)15-6-3-7-16(12-15)30-17-8-4-9-18(13-17)31(2,28)29/h3-13H,1-2H3 FSSRGWRMAQZYCP-UHFFFAOYSA-N 50306029 2-methyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL605314 Oxysterols receptor LXR-beta 799 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306029&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137366 104160390 CHEMBL605314 ZINC45389924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213216 CCc1nc2c(cccn2c1-c1cccc(COc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H21F3N2O3S/c1-3-21-22(29-12-6-11-20(23(29)28-21)24(25,26)27)17-8-4-7-16(13-17)15-32-18-9-5-10-19(14-18)33(2,30)31/h4-14H,3,15H2,1-2H3 AEORKEIKSMCFSB-UHFFFAOYSA-N 50306023 2-ethyl-3-(3-((3-(methylsulfonyl)phenoxy)methyl)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL604905 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306023&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137229 104160384 CHEMBL604905 ZINC45388173 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213217 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(CN3CCSC3)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C25H22F3N3O3S2/c1-36(32,33)20-8-3-7-19(14-20)34-18-6-2-5-17(13-18)23-22(15-30-11-12-35-16-30)29-24-21(25(26,27)28)9-4-10-31(23)24/h2-10,13-14H,11-12,15-16H2,1H3 CBDKGOMYQLDSHF-UHFFFAOYSA-N 50378593 CHEMBL612007 Oxysterols receptor LXR-beta 9 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378593&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877577 160857676 CHEMBL612007 ZINC43206220 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213218 CCc1nc2c(cccn2c1-c1cccc(Cc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H21F3N2O2S/c1-3-21-22(29-12-6-11-20(23(29)28-21)24(25,26)27)18-9-4-7-16(14-18)13-17-8-5-10-19(15-17)32(2,30)31/h4-12,14-15H,3,13H2,1-2H3 YVLZLCWGCDOOAT-UHFFFAOYSA-N 50306022 2-ethyl-3-(3-(3-(methylsulfonyl)benzyl)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL606756 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306022&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46226434 104160383 CHEMBL606756 ZINC45387779 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213219 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(CN3CCCCC3)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C27H26F3N3O3S/c1-37(34,35)22-11-6-10-21(17-22)36-20-9-5-8-19(16-20)25-24(18-32-13-3-2-4-14-32)31-26-23(27(28,29)30)12-7-15-33(25)26/h5-12,15-17H,2-4,13-14,18H2,1H3 BSNQJTLXVANSQQ-UHFFFAOYSA-N 50378592 CHEMBL612006 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378592&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877576 160857675 CHEMBL612006 ZINC49785723 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213220 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(CN3CCCC3)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C26H24F3N3O3S/c1-36(33,34)21-10-5-9-20(16-21)35-19-8-4-7-18(15-19)24-23(17-31-12-2-3-13-31)30-25-22(26(27,28)29)11-6-14-32(24)25/h4-11,14-16H,2-3,12-13,17H2,1H3 HZBNGPXKCIHTTC-UHFFFAOYSA-N 50378591 CHEMBL612005 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378591&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877575 160857674 CHEMBL612005 ZINC49021403 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213223 CC(C)c1nc2c(cccn2c1-c1cccc(OCc2ccc(cc2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C25H23F3N2O3S/c1-16(2)22-23(30-13-5-8-21(24(30)29-22)25(26,27)28)18-6-4-7-19(14-18)33-15-17-9-11-20(12-10-17)34(3,31)32/h4-14,16H,15H2,1-3H3 MWOBQZUUALFLOE-UHFFFAOYSA-N 50306025 2-isopropyl-3-(3-(4-(methylsulfonyl)benzyloxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL606044 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306025&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136349 104160386 CHEMBL606044 ZINC45388307 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213226 CC(C)c1nc2c(cccn2c1-c1cccc(OCc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C25H23F3N2O3S/c1-16(2)22-23(30-12-6-11-21(24(30)29-22)25(26,27)28)18-8-5-9-19(14-18)33-15-17-7-4-10-20(13-17)34(3,31)32/h4-14,16H,15H2,1-3H3 DMUPDMHGBPGHOY-UHFFFAOYSA-N 50306024 2-isopropyl-3-(3-(3-(methylsulfonyl)benzyloxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL596381 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306024&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136346 104160385 CHEMBL596381 ZINC45355601 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213227 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(nc3c(cccn23)C(F)(F)F)-n2ccnc2)c1 InChI=1S/C24H17F3N4O3S/c1-35(32,33)19-8-3-7-18(14-19)34-17-6-2-5-16(13-17)21-23(30-12-10-28-15-30)29-22-20(24(25,26)27)9-4-11-31(21)22/h2-15H,1H3 GRHBEGZXUDYQLG-UHFFFAOYSA-N 50378594 CHEMBL608531 Oxysterols receptor LXR-beta 365 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378594&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877578 160857677 CHEMBL608531 ZINC49109465 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213230 CCc1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C23H19F3N2O3S/c1-3-20-21(28-12-6-11-19(22(28)27-20)23(24,25)26)15-7-4-8-16(13-15)31-17-9-5-10-18(14-17)32(2,29)30/h4-14H,3H2,1-2H3 WZXCTCJIJVBAOX-UHFFFAOYSA-N 50378586 CHEMBL611465 Oxysterols receptor LXR-beta 217 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378586&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137636 160857669 CHEMBL611465 ZINC49052431 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213231 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H18F3NO3S/c1-15-14-28-23-20(10-5-11-21(23)24(25,26)27)22(15)16-6-3-7-17(12-16)31-18-8-4-9-19(13-18)32(2,29)30/h3-14H,1-2H3 ZDUOYBOFMKORCT-UHFFFAOYSA-N 50305077 3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline::CHEMBL595689 Oxysterols receptor LXR-beta 183 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25100150 104159438 CHEMBL595689 ZINC45351156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213232 Cc1nc2c(cccc2n1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C22H17F3N2O3S/c1-14-26-21-19(22(23,24)25)10-5-11-20(21)27(14)15-6-3-7-16(12-15)30-17-8-4-9-18(13-17)31(2,28)29/h3-13H,1-2H3 DGPCIFPFGHXRIB-UHFFFAOYSA-N 50306028 2-methyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594757 Oxysterols receptor LXR-beta 640 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306028&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137576 104160389 CHEMBL594757 ZINC45353000 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213235 CC(C)c1nc2c(cccn2c1-c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H21F3N2O2S/c1-15(2)21-22(29-14-4-5-20(23(29)28-21)24(25,26)27)18-8-6-16(7-9-18)17-10-12-19(13-11-17)32(3,30)31/h4-15H,1-3H3 ZNCGVAYTSJUTKZ-UHFFFAOYSA-N 50306027 2-isopropyl-3-(4'-(methylsulfonyl)biphenyl-4-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL595007 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306027&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137098 104160388 CHEMBL595007 ZINC45339703 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213236 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C28H21F3N2O3S/c1-37(34,35)23-13-6-12-22(18-23)36-21-11-5-10-20(17-21)26-25(16-19-8-3-2-4-9-19)32-27-24(28(29,30)31)14-7-15-33(26)27/h2-15,17-18H,16H2,1H3 JQOXVKXWQCMPRP-UHFFFAOYSA-N 50378590 CHEMBL611735 Oxysterols receptor LXR-beta 5.9 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378590&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 42641405 160857673 CHEMBL611735 ZINC49775306 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213238 CC(C)c1nc2c(cccn2c1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C24H21F3N2O2S/c1-15(2)21-22(29-13-5-8-20(23(29)28-21)24(25,26)27)17-11-9-16(10-12-17)18-6-4-7-19(14-18)32(3,30)31/h4-15H,1-3H3 VVKWAMAHKACEKF-UHFFFAOYSA-N 50306026 2-isopropyl-3-(3'-(methylsulfonyl)biphenyl-4-yl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL595006 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306026&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137094 104160387 CHEMBL595006 ZINC45339701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213239 CS(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(nc3c(cccn23)C(F)(F)F)-c2ccccc2)c1 InChI=1S/C27H19F3N2O3S/c1-36(33,34)22-13-6-12-21(17-22)35-20-11-5-10-19(16-20)25-24(18-8-3-2-4-9-18)31-26-23(27(28,29)30)14-7-15-32(25)26/h2-17H,1H3 GUEIWDLJEBMFMQ-UHFFFAOYSA-N 50378589 CHEMBL611734 Oxysterols receptor LXR-beta 91 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378589&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136969 160857672 CHEMBL611734 ZINC49032179 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213241 CC(C)(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C25H23F3N2O3S/c1-24(2,3)22-21(30-13-7-12-20(23(30)29-22)25(26,27)28)16-8-5-9-17(14-16)33-18-10-6-11-19(15-18)34(4,31)32/h5-15H,1-4H3 LAHPLBHKJGGIEF-UHFFFAOYSA-N 50378588 CHEMBL611467 Oxysterols receptor LXR-beta 222 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378588&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44136717 160857671 CHEMBL611467 ZINC49031157 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213242 CC(C)c1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F InChI=1S/C24H21F3N2O3S/c1-15(2)21-22(29-12-6-11-20(23(29)28-21)24(25,26)27)16-7-4-8-17(13-16)32-18-9-5-10-19(14-18)33(3,30)31/h4-15H,1-3H3 QQDXQGDFJZPVRX-UHFFFAOYSA-N 50378587 CHEMBL611466 Oxysterols receptor LXR-beta 137 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378587&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46877573 160857670 CHEMBL611466 ZINC49792515 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213247 Cc1nc2c(cccn2c1-c1cccc(Oc2cccc(c2)S(=O)(=O)CCCO)c1)C(F)(F)F InChI=1S/C24H21F3N2O4S/c1-16-22(29-11-4-10-21(23(29)28-16)24(25,26)27)17-6-2-7-18(14-17)33-19-8-3-9-20(15-19)34(31,32)13-5-12-30/h2-4,6-11,14-15,30H,5,12-13H2,1H3 BEGFQLFGEWZPNM-UHFFFAOYSA-N 50306032 3-(3-(3-(2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)phenoxy)phenylsulfonyl)propan-1-ol::CHEMBL604701 Oxysterols receptor LXR-beta >1000 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44137503 104160393 CHEMBL604701 ZINC45389854 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50213249 CC(C)S(=O)(=O)c1cccc(Oc2cccc(c2)-c2c(C)nc3c(cccn23)C(F)(F)F)c1 InChI=1S/C24H21F3N2O3S/c1-15(2)33(30,31)20-10-5-9-19(14-20)32-18-8-4-7-17(13-18)22-16(3)28-23-21(24(25,26)27)11-6-12-29(22)23/h4-15H,1-3H3 TXKFTWAELLNECY-UHFFFAOYSA-N 50306031 3-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine::CHEMBL596357 Oxysterols receptor LXR-beta 960 ChEMBL 10.1016/j.bmcl.2009.11.098 10.7270/Q27D2W3S 20005711 Singhaus, RR; Bernotas, RC; Steffan, R; Matelan, E; Quinet, E; Nambi, P; Feingold, I; Huselton, C; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306031&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46226318 104160392 CHEMBL596357 ZINC45364755 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222264 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 501 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222265 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 7.9 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222266 Cn1cnc(c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1c(F)cccc1Cl InChI=1S/C25H23ClFN3O4S2/c1-29-16-25(28-17-29)36(33,34)30(15-22-23(26)7-4-8-24(22)27)14-18-9-11-19(12-10-18)20-5-3-6-21(13-20)35(2,31)32/h3-13,16-17H,14-15H2,1-2H3 AYVVQXQFVKEXMX-UHFFFAOYSA-N 50415815 CHEMBL1092952 Oxysterols receptor LXR-beta 79 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415815&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search G58 3L0E 45100506 163364839 CHEMBL1092952 ZINC44460361 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222267 Cn1cnc(c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1c(F)cccc1Cl InChI=1S/C25H23ClFN3O4S2/c1-29-16-25(28-17-29)36(33,34)30(15-22-23(26)7-4-8-24(22)27)14-18-9-11-19(12-10-18)20-5-3-6-21(13-20)35(2,31)32/h3-13,16-17H,14-15H2,1-2H3 AYVVQXQFVKEXMX-UHFFFAOYSA-N 50415815 CHEMBL1092952 Oxysterols receptor LXR-beta 10 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415815&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search G58 3L0E 45100506 163364839 CHEMBL1092952 ZINC44460361 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222268 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 100 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222269 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 40 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222270 Fc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)Cc1ccc(cc1)-c1cccc(CN2CCNCC2)c1 InChI=1S/C31H32FN3O2S/c32-30-13-15-31(16-14-30)38(36,37)35(23-25-5-2-1-3-6-25)24-26-9-11-28(12-10-26)29-8-4-7-27(21-29)22-34-19-17-33-18-20-34/h1-16,21,33H,17-20,22-24H2 LZBKXBZDNHTOOM-UHFFFAOYSA-N 50415826 CHEMBL1090238 Oxysterols receptor LXR-beta 398 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415826&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46886359 163364850 CHEMBL1090238 ZINC49069098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222271 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 20 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222272 Fc1ccc(CN(Cc2ccc(cc2)-c2ccccc2)S(=O)(=O)c2ccccc2)c(Cl)c1 InChI=1S/C26H21ClFNO2S/c27-26-17-24(28)16-15-23(26)19-29(32(30,31)25-9-5-2-6-10-25)18-20-11-13-22(14-12-20)21-7-3-1-4-8-21/h1-17H,18-19H2 INHFGMLOZMSHPE-UHFFFAOYSA-N 50415824 CHEMBL1090569 Oxysterols receptor LXR-beta 3162 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415824&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202603 163364848 CHEMBL1090569 ZINC49072291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222273 Fc1ccc(CN(Cc2ccccc2)Cc2ccc(cc2)-c2ccccc2)c(Cl)c1 InChI=1S/C27H23ClFN/c28-27-17-26(29)16-15-25(27)20-30(18-21-7-3-1-4-8-21)19-22-11-13-24(14-12-22)23-9-5-2-6-10-23/h1-17H,18-20H2 MUGKNTHVZYSDIV-UHFFFAOYSA-N 50415823 CHEMBL1090570 Oxysterols receptor LXR-beta <10000 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415823&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202604 163364847 CHEMBL1090570 ZINC49072613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222274 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1c(F)cccc1Cl InChI=1S/C30H29ClFNO4S2/c1-20-15-21(2)30(22(3)16-20)39(36,37)33(19-27-28(31)9-6-10-29(27)32)18-23-11-13-24(14-12-23)25-7-5-8-26(17-25)38(4,34)35/h5-17H,18-19H2,1-4H3 NBCKCQXVDMEDRG-UHFFFAOYSA-N 50415818 CHEMBL1093523 Oxysterols receptor LXR-beta 16 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415818&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46203248 163364842 CHEMBL1093523 ZINC49784371 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222275 Fc1ccc(CN(Cc2ccc(cc2)-c2ccccc2)C(=O)c2ccccc2)c(Cl)c1 InChI=1S/C27H21ClFNO/c28-26-17-25(29)16-15-24(26)19-30(27(31)23-9-5-2-6-10-23)18-20-11-13-22(14-12-20)21-7-3-1-4-8-21/h1-17H,18-19H2 SISXRZFAYYJKHJ-UHFFFAOYSA-N 50415822 CHEMBL1091958 Oxysterols receptor LXR-beta <10000 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415822&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202928 163364846 CHEMBL1091958 ZINC49071159 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222276 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1c(F)cccc1Cl InChI=1S/C30H29ClFNO4S2/c1-20-15-21(2)30(22(3)16-20)39(36,37)33(19-27-28(31)9-6-10-29(27)32)18-23-11-13-24(14-12-23)25-7-5-8-26(17-25)38(4,34)35/h5-17H,18-19H2,1-4H3 NBCKCQXVDMEDRG-UHFFFAOYSA-N 50415818 CHEMBL1093523 Oxysterols receptor LXR-beta 16 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415818&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46203248 163364842 CHEMBL1093523 ZINC49784371 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222277 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1ccc(F)cc1Cl InChI=1S/C30H29ClFNO4S2/c1-20-14-21(2)30(22(3)15-20)39(36,37)33(19-26-12-13-27(32)17-29(26)31)18-23-8-10-24(11-9-23)25-6-5-7-28(16-25)38(4,34)35/h5-17H,18-19H2,1-4H3 ZHJGNHDSQQBMTR-UHFFFAOYSA-N 50415817 CHEMBL1093828 Oxysterols receptor LXR-beta 79 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415817&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46203249 163364841 CHEMBL1093828 ZINC49802719 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222278 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1ccc(F)cc1Cl InChI=1S/C30H29ClFNO4S2/c1-20-14-21(2)30(22(3)15-20)39(36,37)33(19-26-12-13-27(32)17-29(26)31)18-23-8-10-24(11-9-23)25-6-5-7-28(16-25)38(4,34)35/h5-17H,18-19H2,1-4H3 ZHJGNHDSQQBMTR-UHFFFAOYSA-N 50415817 CHEMBL1093828 Oxysterols receptor LXR-beta 100 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415817&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46203249 163364841 CHEMBL1093828 ZINC49802719 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222279 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(Cc1ccc(o1)C(F)(F)F)Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C29H28F3NO5S2/c1-19-14-20(2)28(21(3)15-19)40(36,37)33(18-25-12-13-27(38-25)29(30,31)32)17-22-8-10-23(11-9-22)24-6-5-7-26(16-24)39(4,34)35/h5-16H,17-18H2,1-4H3 PSOXOVKYGWBTPB-UHFFFAOYSA-N 50415816 CHEMBL1093266::GSK-2033 Oxysterols receptor LXR-beta 32 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415816&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46203250 163364840 CHEMBL1093266 ZINC49781343 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222280 Cc1ccccc1S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1c(F)cccc1Cl InChI=1S/C28H25ClFNO4S2/c1-20-7-3-4-12-28(20)37(34,35)31(19-25-26(29)10-6-11-27(25)30)18-21-13-15-22(16-14-21)23-8-5-9-24(17-23)36(2,32)33/h3-17H,18-19H2,1-2H3 NTXOQIZNSINWFY-UHFFFAOYSA-N 50415819 CHEMBL1091976 Oxysterols receptor LXR-beta 3.2 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415819&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202932 163364843 CHEMBL1091976 ZINC49781156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222281 CS(=O)(=O)c1cccc(c1)-c1ccc(CN(Cc2ccc(F)cc2Cl)S(=O)(=O)c2ccccc2)cc1 InChI=1S/C27H23ClFNO4S2/c1-35(31,32)26-9-5-6-22(16-26)21-12-10-20(11-13-21)18-30(19-23-14-15-24(29)17-27(23)28)36(33,34)25-7-3-2-4-8-25/h2-17H,18-19H2,1H3 SCYMIMDLYCBIAH-UHFFFAOYSA-N 50415825 CHEMBL1091034 Oxysterols receptor LXR-beta 4 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415825&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202929 163364849 CHEMBL1091034 ZINC49781135 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222282 CS(=O)(=O)c1cccc(c1)-c1ccc(CN(Cc2ccc(F)cc2Cl)S(=O)(=O)c2ccccc2)cc1 InChI=1S/C27H23ClFNO4S2/c1-35(31,32)26-9-5-6-22(16-26)21-12-10-20(11-13-21)18-30(19-23-14-15-24(29)17-27(23)28)36(33,34)25-7-3-2-4-8-25/h2-17H,18-19H2,1H3 SCYMIMDLYCBIAH-UHFFFAOYSA-N 50415825 CHEMBL1091034 Oxysterols receptor LXR-beta 3.2 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415825&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202929 163364849 CHEMBL1091034 ZINC49781135 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222283 CS(=O)(=O)c1cccc(c1)-c1ccc(CN(Cc2c(F)cccc2Cl)S(=O)(=O)c2ccccc2)cc1 InChI=1S/C27H23ClFNO4S2/c1-35(31,32)24-10-5-7-22(17-24)21-15-13-20(14-16-21)18-30(19-25-26(28)11-6-12-27(25)29)36(33,34)23-8-3-2-4-9-23/h2-17H,18-19H2,1H3 SVOYJJLLXFDRBV-UHFFFAOYSA-N 50415821 CHEMBL1093554 Oxysterols receptor LXR-beta 5 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415821&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202930 163364845 CHEMBL1093554 ZINC49802905 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222284 CS(=O)(=O)c1cccc(c1)-c1ccc(CN(Cc2c(F)cccc2Cl)S(=O)(=O)c2ccccc2)cc1 InChI=1S/C27H23ClFNO4S2/c1-35(31,32)24-10-5-7-22(17-24)21-15-13-20(14-16-21)18-30(19-25-26(28)11-6-12-27(25)29)36(33,34)23-8-3-2-4-9-23/h2-17H,18-19H2,1H3 SVOYJJLLXFDRBV-UHFFFAOYSA-N 50415821 CHEMBL1093554 Oxysterols receptor LXR-beta 1 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415821&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202930 163364845 CHEMBL1093554 ZINC49802905 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222285 CS(=O)(=O)c1cccc(c1)-c1ccc(CN(Cc2c(F)cccc2Cl)S(=O)(=O)C2CC2)cc1 InChI=1S/C24H23ClFNO4S2/c1-32(28,29)21-5-2-4-19(14-21)18-10-8-17(9-11-18)15-27(33(30,31)20-12-13-20)16-22-23(25)6-3-7-24(22)26/h2-11,14,20H,12-13,15-16H2,1H3 JOWPSYJSSCKDIQ-UHFFFAOYSA-N 50415820 CHEMBL1093840 Oxysterols receptor LXR-beta 6.3 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415820&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202931 163364844 CHEMBL1093840 ZINC49073475 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222286 CS(=O)(=O)c1cccc(c1)-c1ccc(CN(Cc2c(F)cccc2Cl)S(=O)(=O)C2CC2)cc1 InChI=1S/C24H23ClFNO4S2/c1-32(28,29)21-5-2-4-19(14-21)18-10-8-17(9-11-18)15-27(33(30,31)20-12-13-20)16-22-23(25)6-3-7-24(22)26/h2-11,14,20H,12-13,15-16H2,1H3 JOWPSYJSSCKDIQ-UHFFFAOYSA-N 50415820 CHEMBL1093840 Oxysterols receptor LXR-beta 20 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415820&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202931 163364844 CHEMBL1093840 ZINC49073475 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50222288 Cc1ccccc1S(=O)(=O)N(Cc1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)Cc1c(F)cccc1Cl InChI=1S/C28H25ClFNO4S2/c1-20-7-3-4-12-28(20)37(34,35)31(19-25-26(29)10-6-11-27(25)30)18-21-13-15-22(16-14-21)23-8-5-9-24(17-23)36(2,32)33/h3-17H,18-19H2,1-2H3 NTXOQIZNSINWFY-UHFFFAOYSA-N 50415819 CHEMBL1091976 Oxysterols receptor LXR-beta 13 ChEMBL 10.1021/jm901797p 10.7270/Q2NP25P6 20345102 Zuercher, WJ; Buckholz, RG; Campobasso, N; Collins, JL; Galardi, CM; Gampe, RT; Hyatt, SM; Merrihew, SL; Moore, JT; Oplinger, JA; Reid, PR; Spearing, PK; Stanley, TB; Stewart, EL; Willson, TM GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50415819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50415819&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46202932 163364843 CHEMBL1091976 ZINC49781156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217963 CC(C)CN(c1ccc(cc1)C(O)(C#CC(C)(C)C)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C24H28F3NO3S/c1-18(2)17-28(32(30,31)21-9-7-6-8-10-21)20-13-11-19(12-14-20)23(29,24(25,26)27)16-15-22(3,4)5/h6-14,18,29H,17H2,1-5H3 QZQJBNAIIAODJP-UHFFFAOYSA-N 50390734 CHEMBL2070357 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390734&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042638 160869817 CHEMBL2070357 ZINC84688112 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217964 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C#N)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H23F3N2O3S/c1-20(2)19-32(36(34,35)25-9-4-3-5-10-25)24-13-11-23(12-14-24)26(33,27(28,29)30)16-15-21-7-6-8-22(17-21)18-31/h3-14,17,20,33H,19H2,1-2H3 DQABSMGHWUOXTB-UHFFFAOYSA-N 50390753 CHEMBL2070451 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70697179 160869836 CHEMBL2070451 ZINC84689355 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217965 CC(C)CN(c1ccc(cc1)C(O)(C#CCc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO3S/c1-21(2)20-31(35(33,34)25-13-7-4-8-14-25)24-17-15-23(16-18-24)26(32,27(28,29)30)19-9-12-22-10-5-3-6-11-22/h3-8,10-11,13-18,21,32H,12,20H2,1-2H3 JNRNFUXCVBFFDO-UHFFFAOYSA-N 50390735 CHEMBL2070358 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042617 160869818 CHEMBL2070358 ZINC84688114 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217966 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1C)[N+]([O-])=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H25F3N2O5S/c1-19(2)18-31(38(36,37)25-7-5-4-6-8-25)23-13-10-22(11-14-23)26(33,27(28,29)30)16-15-21-9-12-24(32(34)35)17-20(21)3/h4-14,17,19,33H,18H2,1-3H3 NGVQTVNPIHWYMH-UHFFFAOYSA-N 50390752 CHEMBL2069319 Oxysterols receptor LXR-beta 2800 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70697178 160869835 CHEMBL2069319 ZINC84689353 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217967 OC(C#Cc1ccc(F)cc1)(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C24H16F7NO3S/c25-19-10-6-17(7-11-19)14-15-22(33,24(29,30)31)18-8-12-20(13-9-18)32(16-23(26,27)28)36(34,35)21-4-2-1-3-5-21/h1-13,33H,16H2 YLVSOZLTAZECTH-UHFFFAOYSA-N 50390732 CHEMBL2070355 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390732&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688856 160869815 CHEMBL2070355 ZINC84688081 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217968 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO5S2/c1-20(2)19-31(38(35,36)24-9-5-4-6-10-24)23-14-12-22(13-15-23)26(32,27(28,29)30)17-16-21-8-7-11-25(18-21)37(3,33)34/h4-15,18,20,32H,19H2,1-3H3 WAORBOVWEZBARO-UHFFFAOYSA-N 50390755 CHEMBL2070453 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042641 160869838 CHEMBL2070453 ZINC84688470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217969 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)C#N)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H22F3N3O3S/c1-20(2)19-34(38(36,37)26-5-3-4-23(16-26)18-33)25-12-10-24(11-13-25)27(35,28(29,30)31)15-14-21-6-8-22(17-32)9-7-21/h3-13,16,20,35H,19H2,1-2H3 WURQNCCSOKMJQO-UHFFFAOYSA-N 50390754 CHEMBL2070452 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686781 160869837 CHEMBL2070452 ZINC84689357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217970 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C26H24F3NO3S/c1-20(2)19-30(34(32,33)24-11-7-4-8-12-24)23-15-13-22(14-16-23)25(31,26(27,28)29)18-17-21-9-5-3-6-10-21/h3-16,20,31H,19H2,1-2H3 AMTGRPHGLMMWGU-UHFFFAOYSA-N 50390733 CHEMBL2070356 Oxysterols receptor LXR-beta 8000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390733&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042597 160869816 CHEMBL2070356 ZINC84688083 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217971 COc1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C27H26F3NO4S/c1-20(2)19-31(36(33,34)25-7-5-4-6-8-25)23-13-11-22(12-14-23)26(32,27(28,29)30)18-17-21-9-15-24(35-3)16-10-21/h4-16,20,32H,19H2,1-3H3 SPBPFJHZPFDYNQ-UHFFFAOYSA-N 50390747 CHEMBL2070371 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042636 160869830 CHEMBL2070371 ZINC84690742 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217972 CC(C)CN(c1ccc(cc1)C(O)(C#CC1=CCCCC1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C26H28F3NO3S/c1-20(2)19-30(34(32,33)24-11-7-4-8-12-24)23-15-13-22(14-16-23)25(31,26(27,28)29)18-17-21-9-5-3-6-10-21/h4,7-9,11-16,20,31H,3,5-6,10,19H2,1-2H3 NNEYGSCCUBHPHI-UHFFFAOYSA-N 50390736 CHEMBL2070359 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042624 160869819 CHEMBL2070359 ZINC84688116 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217973 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccn1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C25H23F3N2O3S/c1-19(2)18-30(34(32,33)23-9-4-3-5-10-23)22-13-11-20(12-14-22)24(31,25(26,27)28)16-15-21-8-6-7-17-29-21/h3-14,17,19,31H,18H2,1-2H3 HMBODJGXCWBXQN-UHFFFAOYSA-N 50390737 CHEMBL2070360 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 21037789 160869820 CHEMBL2070360 ZINC84688118 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217974 CCOc1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C28H28F3NO4S/c1-4-36-25-16-10-22(11-17-25)18-19-27(33,28(29,30)31)23-12-14-24(15-13-23)32(20-21(2)3)37(34,35)26-8-6-5-7-9-26/h5-17,21,33H,4,20H2,1-3H3 GUGYXTSGMDPJSE-UHFFFAOYSA-N 50390748 CHEMBL2070372 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390748&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70684628 160869831 CHEMBL2070372 ZINC84689289 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217975 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C(O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H24F3NO5S/c1-19(2)18-31(37(35,36)24-9-4-3-5-10-24)23-13-11-22(12-14-23)26(34,27(28,29)30)16-15-20-7-6-8-21(17-20)25(32)33/h3-14,17,19,34H,18H2,1-2H3,(H,32,33) JZDDMLSUAKIVJW-UHFFFAOYSA-N 50390761 CHEMBL2070459 Oxysterols receptor LXR-beta 1800 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390761&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688866 160869844 CHEMBL2070459 ZINC84709675 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217976 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(=O)(=O)c1ccccc1)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C33H27F3N2O5S2/c1-24(2)23-38(45(42,43)31-10-6-7-26(21-31)22-37)28-15-13-27(14-16-28)32(39,33(34,35)36)20-19-25-11-17-30(18-12-25)44(40,41)29-8-4-3-5-9-29/h3-18,21,24,39H,23H2,1-2H3 WFJUHKZIXXAQEK-UHFFFAOYSA-N 50390760 CHEMBL2070458 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688865 160869843 CHEMBL2070458 ZINC84709671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50217977 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO5S2/c1-20(2)19-31(38(35,36)25-7-5-4-6-8-25)23-13-11-22(12-14-23)26(32,27(28,29)30)18-17-21-9-15-24(16-10-21)37(3,33)34/h4-16,20,32H,19H2,1-3H3 SVEVEXKUDJROGZ-UHFFFAOYSA-N 50390757 CHEMBL2070455 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390757&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042579 160869840 CHEMBL2070455 ZINC84710484 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218000 CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C23H18F3NO3S/c1-27(31(29,30)21-10-6-3-7-11-21)20-14-12-19(13-15-20)22(28,23(24,25)26)17-16-18-8-4-2-5-9-18/h2-15,28H,1H3 DHNCBPDODFIQEF-UHFFFAOYSA-N 50390731 CHEMBL2070354 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390731&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042608 160869814 CHEMBL2070354 ZINC84688079 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218001 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H25F3N2O5S2/c1-20(2)19-33(40(37,38)26-9-5-7-22(17-26)18-32)24-12-10-23(11-13-24)27(34,28(29,30)31)15-14-21-6-4-8-25(16-21)39(3,35)36/h4-13,16-17,20,34H,19H2,1-3H3 WYHNSMFWOKJJLK-UHFFFAOYSA-N 50390756 CHEMBL2070454 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70690946 160869839 CHEMBL2070454 ZINC84688472 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218002 CN(c1ccc(cc1)C(O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C15H14F3NO3S/c1-19(23(21,22)13-5-3-2-4-6-13)12-9-7-11(8-10-12)14(20)15(16,17)18/h2-10,14,20H,1H3 UJIROJYBEYJMTN-UHFFFAOYSA-N 50179868 CHEMBL203454::N-methyl-N-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)benzenesulfonamide Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179868&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44409123 104065015 CHEMBL203454 ZINC28571724 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218003 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(=O)(=O)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H22F6N2O5S2/c1-19(2)18-36(43(40,41)25-5-3-4-21(16-25)17-35)23-10-8-22(9-11-23)26(37,27(29,30)31)15-14-20-6-12-24(13-7-20)42(38,39)28(32,33)34/h3-13,16,19,37H,18H2,1-2H3 SDOPOZOIFATKAJ-UHFFFAOYSA-N 50390759 CHEMBL2070457 Oxysterols receptor LXR-beta 4300 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70693093 160869842 CHEMBL2070457 ZINC84709667 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218004 CN(c1ccc(cc1)C(O)(C#CC(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C18H13F6NO3S/c1-25(29(27,28)15-5-3-2-4-6-15)14-9-7-13(8-10-14)16(26,18(22,23)24)11-12-17(19,20)21/h2-10,26H,1H3 JVONGVKVZXBCEF-UHFFFAOYSA-N 50390729 CHEMBL2070352 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390729&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042604 160869812 CHEMBL2070352 ZINC84689784 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218005 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H25F3N2O5S2/c1-20(2)19-33(40(37,38)26-6-4-5-22(17-26)18-32)24-11-9-23(10-12-24)27(34,28(29,30)31)16-15-21-7-13-25(14-8-21)39(3,35)36/h4-14,17,20,34H,19H2,1-3H3 MFQZKIZCIAGJJR-UHFFFAOYSA-N 50390758 CHEMBL2070456 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390758&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042652 160869841 CHEMBL2070456 ZINC84709662 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218006 CN(c1ccc(cc1)C(O)(Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C22H20F3NO3S/c1-26(30(28,29)20-10-6-3-7-11-20)19-14-12-18(13-15-19)21(27,22(23,24)25)16-17-8-4-2-5-9-17/h2-15,27H,16H2,1H3 OVTATVLBBXTEKN-UHFFFAOYSA-N 50390723 CHEMBL2070346 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390723&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686771 160869806 CHEMBL2070346 ZINC84690367 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218007 CN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C17H13F8NO3S/c1-26(30(28,29)13-5-3-2-4-6-13)12-9-7-11(8-10-12)14(27,16(20,21)22)15(18,19)17(23,24)25/h2-10,27H,1H3 YCIQIRLTSAQVSK-UHFFFAOYSA-N 50390722 CHEMBL2070345 Oxysterols receptor LXR-beta 160 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390722&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70682541 160869805 CHEMBL2070345 ZINC84672413 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218008 CN(c1ccc(cc1)C(O)(c1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C21H18F3NO3S/c1-25(29(27,28)19-10-6-3-7-11-19)18-14-12-17(13-15-18)20(26,21(22,23)24)16-8-4-2-5-9-16/h2-15,26H,1H3 JMAHWDNJLLYEPP-UHFFFAOYSA-N 50390725 CHEMBL2070348 Oxysterols receptor LXR-beta 3600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390725&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686772 160869808 CHEMBL2070348 ZINC84690371 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218009 CN(c1ccc(cc1)C(O)(c1cccs1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C19H16F3NO3S2/c1-23(28(25,26)16-6-3-2-4-7-16)15-11-9-14(10-12-15)18(24,19(20,21)22)17-8-5-13-27-17/h2-13,24H,1H3 MEDXAXAYXXHRHQ-UHFFFAOYSA-N 50390724 CHEMBL2070347 Oxysterols receptor LXR-beta 1500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390724&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70695131 160869807 CHEMBL2070347 ZINC84690369 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218010 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H23F6NO3S/c1-19(2)18-34(38(36,37)24-9-4-3-5-10-24)23-13-11-21(12-14-23)25(35,27(31,32)33)16-15-20-7-6-8-22(17-20)26(28,29)30/h3-14,17,19,35H,18H2,1-2H3 IPVOYRALYXDGRZ-UHFFFAOYSA-N 50390745 CHEMBL2070368 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042645 160869828 CHEMBL2070368 ZINC84687794 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218011 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CCC(F)(F)F)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C26H21F6NO5S2/c1-39(35,36)22-13-7-19(8-14-22)15-16-24(34,26(30,31)32)20-9-11-21(12-10-20)33(18-17-25(27,28)29)40(37,38)23-5-3-2-4-6-23/h2-14,34H,17-18H2,1H3 ABXFBIHMTMSADH-UHFFFAOYSA-N 50390764 CHEMBL2070462 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390764&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70684639 160869847 CHEMBL2070462 ZINC84690268 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218012 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H23F6NO3S/c1-19(2)18-34(38(36,37)24-6-4-3-5-7-24)23-14-12-21(13-15-23)25(35,27(31,32)33)17-16-20-8-10-22(11-9-20)26(28,29)30/h3-15,19,35H,18H2,1-2H3 FAEPYFWSINNSSR-UHFFFAOYSA-N 50390746 CHEMBL2070369 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042583 160869829 CHEMBL2070369 ZINC84690738 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218013 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C25H19F6NO5S2/c1-38(34,35)21-13-7-18(8-14-21)15-16-23(33,25(29,30)31)19-9-11-20(12-10-19)32(17-24(26,27)28)39(36,37)22-5-3-2-4-6-22/h2-14,33H,17H2,1H3 KWVKCBHTUNENFK-UHFFFAOYSA-N 50390763 CHEMBL2070461 Oxysterols receptor LXR-beta 1000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390763&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70690947 160869846 CHEMBL2070461 ZINC84690527 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218014 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1cc(Cl)ccc1Cl InChI=1S/C26H22Cl2F3NO3S/c1-18(2)17-32(36(34,35)24-16-21(27)10-13-23(24)28)22-11-8-20(9-12-22)25(33,26(29,30)31)15-14-19-6-4-3-5-7-19/h3-13,16,18,33H,17H2,1-2H3 OPWASPRJSUBIAP-UHFFFAOYSA-N 50390743 CHEMBL2070366 Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042647 160869826 CHEMBL2070366 ZINC84687790 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218015 CN(c1ccc(cc1)C(C)(O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C16H16F3NO3S/c1-15(21,16(17,18)19)12-8-10-13(11-9-12)20(2)24(22,23)14-6-4-3-5-7-14/h3-11,21H,1-2H3 QYKBEJIHKYFJQV-UHFFFAOYSA-N 50179871 CHEMBL383657::N-methyl-N-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl)benzenesulfonamide Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179871&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 20704168 104065018 CHEMBL383657 ZINC38156022 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218016 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CC1)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C27H24F3NO5S2/c1-37(33,34)24-15-9-20(10-16-24)17-18-26(32,27(28,29)30)22-11-13-23(14-12-22)31(19-21-7-8-21)38(35,36)25-5-3-2-4-6-25/h2-6,9-16,21,32H,7-8,19H2,1H3 NMMZNDAQGGNURI-UHFFFAOYSA-N 50390765 CHEMBL2070464 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390765&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24767795 160869848 CHEMBL2070464 ZINC84690535 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218017 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(Cl)cc1)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C27H22ClF3N2O3S/c1-19(2)18-33(37(35,36)25-5-3-4-21(16-25)17-32)24-12-8-22(9-13-24)26(34,27(29,30)31)15-14-20-6-10-23(28)11-7-20/h3-13,16,19,34H,18H2,1-2H3 DFDDEXIVIDCBJU-UHFFFAOYSA-N 50390744 CHEMBL2070367 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042593 160869827 CHEMBL2070367 ZINC84687792 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218018 COC(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H15F6NO3S/c1-24(28(25,26)14-6-4-3-5-7-14)13-10-8-12(9-11-13)15(27-2,16(18,19)20)17(21,22)23/h3-11H,1-2H3 CSIZNYPDEUPVKZ-UHFFFAOYSA-N 50179862 CHEMBL203824::N-(4-(1,1,1,3,3,3-hexafluoro-2-methoxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide Oxysterols receptor LXR-beta 2200 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179862&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 20704187 104065009 CHEMBL203824 ZINC28572564 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218019 CC(C)(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C28H28F3NO5S2/c1-26(2,3)20-32(39(36,37)25-8-6-5-7-9-25)23-14-12-22(13-15-23)27(33,28(29,30)31)19-18-21-10-16-24(17-11-21)38(4,34)35/h5-17,33H,20H2,1-4H3 ZATNJKHDTLHDQN-UHFFFAOYSA-N 50390766 CHEMBL2070463 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390766&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686782 160869849 CHEMBL2070463 ZINC84690270 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218020 CN(c1ccc(cc1)C(O)(c1ncc[nH]1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C18H16F3N3O3S/c1-24(28(26,27)15-5-3-2-4-6-15)14-9-7-13(8-10-14)17(25,18(19,20)21)16-22-11-12-23-16/h2-12,25H,1H3,(H,22,23) MWXVHGFPIVOMOJ-UHFFFAOYSA-N 50390727 CHEMBL2070350 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390727&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70682542 160869810 CHEMBL2070350 ZINC84690373 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218021 CN(c1ccc(cc1)C(O)(c1nccs1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C18H15F3N2O3S2/c1-23(28(25,26)15-5-3-2-4-6-15)14-9-7-13(8-10-14)17(24,18(19,20)21)16-22-11-12-27-16/h2-12,24H,1H3 UCZDQYJULUTAJR-UHFFFAOYSA-N 50390726 CHEMBL2070349 Oxysterols receptor LXR-beta 7500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390726&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042654 160869809 CHEMBL2070349 ZINC84687169 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218022 COc1cccc(c1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C27H26F3NO4S/c1-20(2)19-31(36(33,34)25-10-5-4-6-11-25)23-14-12-22(13-15-23)26(32,27(28,29)30)17-16-21-8-7-9-24(18-21)35-3/h4-15,18,20,32H,19H2,1-3H3 WGCDCIPOZNKVON-UHFFFAOYSA-N 50390769 CHEMBL2070370 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390769&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70697169 160869852 CHEMBL2070370 ZINC84690740 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218023 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)C(O)=O)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H23F3N2O5S/c1-19(2)18-33(39(37,38)25-5-3-4-21(16-25)17-32)24-12-10-23(11-13-24)27(36,28(29,30)31)15-14-20-6-8-22(9-7-20)26(34)35/h3-13,16,19,36H,18H2,1-2H3,(H,34,35) BDTIEODGWNQJHA-UHFFFAOYSA-N 50390762 CHEMBL2070460 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390762&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70693094 160869845 CHEMBL2070460 ZINC84690525 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218024 CN(c1ccc(cc1)C(O)(c1nnc[nH]1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C17H15F3N4O3S/c1-24(28(26,27)14-5-3-2-4-6-14)13-9-7-12(8-10-13)16(25,17(18,19)20)15-21-11-22-23-15/h2-11,25H,1H3,(H,21,22,23) VNLUTNLAJAYTAE-UHFFFAOYSA-N 50390728 CHEMBL2070351 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390728&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686773 160869811 CHEMBL2070351 ZINC84689780 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218025 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(C)cc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO3S/c1-20(2)19-31(35(33,34)25-7-5-4-6-8-25)24-15-13-23(14-16-24)26(32,27(28,29)30)18-17-22-11-9-21(3)10-12-22/h4-16,20,32H,19H2,1-3H3 HOKWHENHZPOIMO-UHFFFAOYSA-N 50390749 CHEMBL2070448 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390749&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042570 160869832 CHEMBL2070448 ZINC84709563 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218026 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccnc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C25H23F3N2O3S/c1-19(2)18-30(34(32,33)23-8-4-3-5-9-23)22-12-10-21(11-13-22)24(31,25(26,27)28)15-14-20-7-6-16-29-17-20/h3-13,16-17,19,31H,18H2,1-2H3 YMCZPIAWBPMWLT-UHFFFAOYSA-N 50390738 CHEMBL2070361 Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042611 160869821 CHEMBL2070361 ZINC84687455 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218027 CCCCc1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C30H32F3NO3S/c1-4-5-9-24-12-14-25(15-13-24)20-21-29(35,30(31,32)33)26-16-18-27(19-17-26)34(22-23(2)3)38(36,37)28-10-7-6-8-11-28/h6-8,10-19,23,35H,4-5,9,22H2,1-3H3 XKVLTCFSICEGEB-UHFFFAOYSA-N 50390750 CHEMBL2070449 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70695140 160869833 CHEMBL2070449 ZINC84709567 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218028 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CCCC1)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C29H28F3NO5S2/c1-39(35,36)26-17-11-22(12-18-26)19-20-28(34,29(30,31)32)24-13-15-25(16-14-24)33(21-23-7-5-6-8-23)40(37,38)27-9-3-2-4-10-27/h2-4,9-18,23,34H,5-8,21H2,1H3 RXPXFGQFOCMGBP-UHFFFAOYSA-N 50390768 CHEMBL2070466 Oxysterols receptor LXR-beta 150 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390768&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686783 160869851 CHEMBL2070466 ZINC84704123 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218029 CCn1cc(cn1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C25H26F3N3O3S/c1-4-30-18-20(16-29-30)14-15-24(32,25(26,27)28)21-10-12-22(13-11-21)31(17-19(2)3)35(33,34)23-8-6-5-7-9-23/h5-13,16,18-19,32H,4,17H2,1-3H3 PIRHVCWFGBWSLW-UHFFFAOYSA-N 50390741 CHEMBL2070364 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042560 160869824 CHEMBL2070364 ZINC84688423 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218030 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CCC1)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C28H26F3NO5S2/c1-38(34,35)25-16-10-21(11-17-25)18-19-27(33,28(29,30)31)23-12-14-24(15-13-23)32(20-22-6-5-7-22)39(36,37)26-8-3-2-4-9-26/h2-4,8-17,22,33H,5-7,20H2,1H3 AQIOHOLALGMEGV-UHFFFAOYSA-N 50390767 CHEMBL2070465 Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390767&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70682550 160869850 CHEMBL2070465 ZINC84690993 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218031 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C27H23F3N2O3S/c1-20(2)19-32(36(34,35)25-10-6-9-22(17-25)18-31)24-13-11-23(12-14-24)26(33,27(28,29)30)16-15-21-7-4-3-5-8-21/h3-14,17,20,33H,19H2,1-2H3 UPBQKZKPZNVPRI-UHFFFAOYSA-N 50390742 CHEMBL2070365 Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042616 160869825 CHEMBL2070365 ZINC84687788 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218032 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cncn1C)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C24H24F3N3O3S/c1-18(2)16-30(34(32,33)22-7-5-4-6-8-22)20-11-9-19(10-12-20)23(31,24(25,26)27)14-13-21-15-28-17-29(21)3/h4-12,15,17-18,31H,16H2,1-3H3 WIPLZYJMGYWIBT-UHFFFAOYSA-N 50390739 CHEMBL2070362 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688857 160869822 CHEMBL2070362 ZINC84687457 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218033 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(F)cc1F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C26H22F5NO3S/c1-18(2)17-32(36(34,35)23-6-4-3-5-7-23)22-12-9-20(10-13-22)25(33,26(29,30)31)15-14-19-8-11-21(27)16-24(19)28/h3-13,16,18,33H,17H2,1-2H3 YDKXCKPEVZQWEP-UHFFFAOYSA-N 50390751 CHEMBL2070450 Oxysterols receptor LXR-beta 8000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042586 160869834 CHEMBL2070450 ZINC84710437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218034 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1c(C)noc1C)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C25H25F3N2O4S/c1-17(2)16-30(35(32,33)22-8-6-5-7-9-22)21-12-10-20(11-13-21)24(31,25(26,27)28)15-14-23-18(3)29-34-19(23)4/h5-13,17,31H,16H2,1-4H3 GNIXZJMDDPSKAJ-UHFFFAOYSA-N 50390740 CHEMBL2070363 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70693085 160869823 CHEMBL2070363 ZINC84688421 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218035 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO5S2/c1-20(2)19-31(38(35,36)25-7-5-4-6-8-25)23-13-11-22(12-14-23)26(32,27(28,29)30)18-17-21-9-15-24(16-10-21)37(3,33)34/h4-16,20,32H,19H2,1-3H3 SVEVEXKUDJROGZ-UHFFFAOYSA-N 50390757 CHEMBL2070455 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390757&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042579 160869840 CHEMBL2070455 ZINC84710484 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218036 CC(C)CC#CC(O)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C21H22F3NO3S/c1-16(2)8-7-15-20(26,21(22,23)24)17-11-13-18(14-12-17)25(3)29(27,28)19-9-5-4-6-10-19/h4-6,9-14,16,26H,8H2,1-3H3 JTRCVYFIPTWBIX-UHFFFAOYSA-N 50390730 CHEMBL2070353 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390730&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042637 160869813 CHEMBL2070353 ZINC84689786 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50221387 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 110 ChEMBL 10.1016/j.bmcl.2012.04.071 10.7270/Q25D8SZD 22579484 Hoang, MH; Jia, Y; Jun, HJ; Lee, JH; Lee, DH; Hwang, BY; Kim, WJ; Lee, HJ; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50221389 CCOC(=O)c1c(O)cc(O)cc1O InChI=1S/C9H10O5/c1-2-14-9(13)8-6(11)3-5(10)4-7(8)12/h3-4,10-12H,2H2,1H3 UBOJATHNUASNAV-UHFFFAOYSA-N 50401084 CHEMBL2204435 Oxysterols receptor LXR-beta 37800 ChEMBL 10.1016/j.bmcl.2012.04.071 10.7270/Q25D8SZD 22579484 Hoang, MH; Jia, Y; Jun, HJ; Lee, JH; Lee, DH; Hwang, BY; Kim, WJ; Lee, HJ; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401084&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 54344821 163350108 CHEMBL2204435 ZINC14775716 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50221391 CCOC(=O)c1c(O)cc(O)cc1O InChI=1S/C9H10O5/c1-2-14-9(13)8-6(11)3-5(10)4-7(8)12/h3-4,10-12H,2H2,1H3 UBOJATHNUASNAV-UHFFFAOYSA-N 50401084 CHEMBL2204435 Oxysterols receptor LXR-beta 3040 ChEMBL 10.1016/j.bmcl.2012.04.071 10.7270/Q25D8SZD 22579484 Hoang, MH; Jia, Y; Jun, HJ; Lee, JH; Lee, DH; Hwang, BY; Kim, WJ; Lee, HJ; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401084&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 54344821 163350108 CHEMBL2204435 ZINC14775716 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218062 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H25F3N2O5S2/c1-20(2)19-33(40(37,38)26-6-4-5-22(17-26)18-32)24-11-9-23(10-12-24)27(34,28(29,30)31)16-15-21-7-13-25(14-8-21)39(3,35)36/h4-14,17,20,34H,19H2,1-3H3 MFQZKIZCIAGJJR-UHFFFAOYSA-N 50390758 CHEMBL2070456 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390758&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042652 160869841 CHEMBL2070456 ZINC84709662 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218064 CN(c1ccc(cc1)C(O)(C#CC(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C18H13F6NO3S/c1-25(29(27,28)15-5-3-2-4-6-15)14-9-7-13(8-10-14)16(26,18(22,23)24)11-12-17(19,20)21/h2-10,26H,1H3 JVONGVKVZXBCEF-UHFFFAOYSA-N 50390729 CHEMBL2070352 Oxysterols receptor LXR-beta 4100 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390729&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042604 160869812 CHEMBL2070352 ZINC84689784 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218065 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO5S2/c1-20(2)19-31(38(35,36)24-9-5-4-6-10-24)23-14-12-22(13-15-23)26(32,27(28,29)30)17-16-21-8-7-11-25(18-21)37(3,33)34/h4-15,18,20,32H,19H2,1-3H3 WAORBOVWEZBARO-UHFFFAOYSA-N 50390755 CHEMBL2070453 Oxysterols receptor LXR-beta 5000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042641 160869838 CHEMBL2070453 ZINC84688470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218066 OC(C#Cc1ccc(F)cc1)(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C24H16F7NO3S/c25-19-10-6-17(7-11-19)14-15-22(33,24(29,30)31)18-8-12-20(13-9-18)32(16-23(26,27)28)36(34,35)21-4-2-1-3-5-21/h1-13,33H,16H2 YLVSOZLTAZECTH-UHFFFAOYSA-N 50390732 CHEMBL2070355 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390732&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688856 160869815 CHEMBL2070355 ZINC84688081 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218067 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H25F3N2O5S2/c1-20(2)19-33(40(37,38)26-9-5-7-22(17-26)18-32)24-12-10-23(11-13-24)27(34,28(29,30)31)15-14-21-6-4-8-25(16-21)39(3,35)36/h4-13,16-17,20,34H,19H2,1-3H3 WYHNSMFWOKJJLK-UHFFFAOYSA-N 50390756 CHEMBL2070454 Oxysterols receptor LXR-beta 7000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70690946 160869839 CHEMBL2070454 ZINC84688472 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218068 CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C23H18F3NO3S/c1-27(31(29,30)21-10-6-3-7-11-21)20-14-12-19(13-15-20)22(28,23(24,25)26)17-16-18-8-4-2-5-9-18/h2-15,28H,1H3 DHNCBPDODFIQEF-UHFFFAOYSA-N 50390731 CHEMBL2070354 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390731&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042608 160869814 CHEMBL2070354 ZINC84688079 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218069 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C(O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H24F3NO5S/c1-19(2)18-31(37(35,36)24-9-4-3-5-10-24)23-13-11-22(12-14-23)26(34,27(28,29)30)16-15-20-7-6-8-21(17-20)25(32)33/h3-14,17,19,34H,18H2,1-2H3,(H,32,33) JZDDMLSUAKIVJW-UHFFFAOYSA-N 50390761 CHEMBL2070459 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390761&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688866 160869844 CHEMBL2070459 ZINC84709675 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218070 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(=O)(=O)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H22F6N2O5S2/c1-19(2)18-36(43(40,41)25-5-3-4-21(16-25)17-35)23-10-8-22(9-11-23)26(37,27(29,30)31)15-14-20-6-12-24(13-7-20)42(38,39)28(32,33)34/h3-13,16,19,37H,18H2,1-2H3 SDOPOZOIFATKAJ-UHFFFAOYSA-N 50390759 CHEMBL2070457 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70693093 160869842 CHEMBL2070457 ZINC84709667 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218071 CN(c1ccc(cc1)C(O)(c1nnn[nH]1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C16H14F3N5O3S/c1-24(28(26,27)13-5-3-2-4-6-13)12-9-7-11(8-10-12)15(25,16(17,18)19)14-20-22-23-21-14/h2-10,25H,1H3,(H,20,21,22,23) PBNVATIVYNXFNX-UHFFFAOYSA-N 50390770 CHEMBL2069318 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390770&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70697168 160869853 CHEMBL2069318 ZINC84689782 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218072 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(=O)(=O)c1ccccc1)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C33H27F3N2O5S2/c1-24(2)23-38(45(42,43)31-10-6-7-26(21-31)22-37)28-15-13-27(14-16-28)32(39,33(34,35)36)20-19-25-11-17-30(18-12-25)44(40,41)29-8-4-3-5-9-29/h3-18,21,24,39H,23H2,1-2H3 WFJUHKZIXXAQEK-UHFFFAOYSA-N 50390760 CHEMBL2070458 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688865 160869843 CHEMBL2070458 ZINC84709671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218073 COc1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C27H26F3NO4S/c1-20(2)19-31(36(33,34)25-7-5-4-6-8-25)23-13-11-22(12-14-23)26(32,27(28,29)30)18-17-21-9-15-24(35-3)16-10-21/h4-16,20,32H,19H2,1-3H3 SPBPFJHZPFDYNQ-UHFFFAOYSA-N 50390747 CHEMBL2070371 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042636 160869830 CHEMBL2070371 ZINC84690742 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218074 CCOc1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C28H28F3NO4S/c1-4-36-25-16-10-22(11-17-25)18-19-27(33,28(29,30)31)23-12-14-24(15-13-23)32(20-21(2)3)37(34,35)26-8-6-5-7-9-26/h5-17,21,33H,4,20H2,1-3H3 GUGYXTSGMDPJSE-UHFFFAOYSA-N 50390748 CHEMBL2070372 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390748&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70684628 160869831 CHEMBL2070372 ZINC84689289 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218075 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccn1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C25H23F3N2O3S/c1-19(2)18-30(34(32,33)23-9-4-3-5-10-23)22-13-11-20(12-14-22)24(31,25(26,27)28)16-15-21-8-6-7-17-29-21/h3-14,17,19,31H,18H2,1-2H3 HMBODJGXCWBXQN-UHFFFAOYSA-N 50390737 CHEMBL2070360 Oxysterols receptor LXR-beta 3800 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 21037789 160869820 CHEMBL2070360 ZINC84688118 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218076 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C#N)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H23F3N2O3S/c1-20(2)19-32(36(34,35)25-9-4-3-5-10-25)24-13-11-23(12-14-24)26(33,27(28,29)30)16-15-21-7-6-8-22(17-21)18-31/h3-14,17,20,33H,19H2,1-2H3 DQABSMGHWUOXTB-UHFFFAOYSA-N 50390753 CHEMBL2070451 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70697179 160869836 CHEMBL2070451 ZINC84689355 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218077 CC(C)CN(c1ccc(cc1)C(O)(C#CC(C)(C)C)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C24H28F3NO3S/c1-18(2)17-28(32(30,31)21-9-7-6-8-10-21)20-13-11-19(12-14-20)23(29,24(25,26)27)16-15-22(3,4)5/h6-14,18,29H,17H2,1-5H3 QZQJBNAIIAODJP-UHFFFAOYSA-N 50390734 CHEMBL2070357 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390734&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042638 160869817 CHEMBL2070357 ZINC84688112 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218078 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)C#N)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H22F3N3O3S/c1-20(2)19-34(38(36,37)26-5-3-4-23(16-26)18-33)25-12-10-24(11-13-25)27(35,28(29,30)31)15-14-21-6-8-22(17-32)9-7-21/h3-13,16,20,35H,19H2,1-2H3 WURQNCCSOKMJQO-UHFFFAOYSA-N 50390754 CHEMBL2070452 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686781 160869837 CHEMBL2070452 ZINC84689357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218079 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C26H24F3NO3S/c1-20(2)19-30(34(32,33)24-11-7-4-8-12-24)23-15-13-22(14-16-23)25(31,26(27,28)29)18-17-21-9-5-3-6-10-21/h3-16,20,31H,19H2,1-2H3 AMTGRPHGLMMWGU-UHFFFAOYSA-N 50390733 CHEMBL2070356 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390733&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042597 160869816 CHEMBL2070356 ZINC84688083 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218080 CC(C)CN(c1ccc(cc1)C(O)(C#CC1=CCCCC1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C26H28F3NO3S/c1-20(2)19-30(34(32,33)24-11-7-4-8-12-24)23-15-13-22(14-16-23)25(31,26(27,28)29)18-17-21-9-5-3-6-10-21/h4,7-9,11-16,20,31H,3,5-6,10,19H2,1-2H3 NNEYGSCCUBHPHI-UHFFFAOYSA-N 50390736 CHEMBL2070359 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042624 160869819 CHEMBL2070359 ZINC84688116 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218081 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1C)[N+]([O-])=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H25F3N2O5S/c1-19(2)18-31(38(36,37)25-7-5-4-6-8-25)23-13-10-22(11-14-23)26(33,27(28,29)30)16-15-21-9-12-24(32(34)35)17-20(21)3/h4-14,17,19,33H,18H2,1-3H3 NGVQTVNPIHWYMH-UHFFFAOYSA-N 50390752 CHEMBL2069319 Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70697178 160869835 CHEMBL2069319 ZINC84689353 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218082 CC(C)CN(c1ccc(cc1)C(O)(C#CCc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO3S/c1-21(2)20-31(35(33,34)25-13-7-4-8-14-25)24-17-15-23(16-18-24)26(32,27(28,29)30)19-9-12-22-10-5-3-6-11-22/h3-8,10-11,13-18,21,32H,12,20H2,1-2H3 JNRNFUXCVBFFDO-UHFFFAOYSA-N 50390735 CHEMBL2070358 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042617 160869818 CHEMBL2070358 ZINC84688114 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218083 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CCCC1)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C29H28F3NO5S2/c1-39(35,36)26-17-11-22(12-18-26)19-20-28(34,29(30,31)32)24-13-15-25(16-14-24)33(21-23-7-5-6-8-23)40(37,38)27-9-3-2-4-10-27/h2-4,9-18,23,34H,5-8,21H2,1H3 RXPXFGQFOCMGBP-UHFFFAOYSA-N 50390768 CHEMBL2070466 Oxysterols receptor LXR-beta 1500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390768&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686783 160869851 CHEMBL2070466 ZINC84704123 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218084 CCn1cc(cn1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C25H26F3N3O3S/c1-4-30-18-20(16-29-30)14-15-24(32,25(26,27)28)21-10-12-22(13-11-21)31(17-19(2)3)35(33,34)23-8-6-5-7-9-23/h5-13,16,18-19,32H,4,17H2,1-3H3 PIRHVCWFGBWSLW-UHFFFAOYSA-N 50390741 CHEMBL2070364 Oxysterols receptor LXR-beta 1700 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042560 160869824 CHEMBL2070364 ZINC84688423 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218085 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1c(C)noc1C)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C25H25F3N2O4S/c1-17(2)16-30(35(32,33)22-8-6-5-7-9-22)21-12-10-20(11-13-21)24(31,25(26,27)28)15-14-23-18(3)29-34-19(23)4/h5-13,17,31H,16H2,1-4H3 GNIXZJMDDPSKAJ-UHFFFAOYSA-N 50390740 CHEMBL2070363 Oxysterols receptor LXR-beta 3200 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70693085 160869823 CHEMBL2070363 ZINC84688421 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218086 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CC1)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C27H24F3NO5S2/c1-37(33,34)24-15-9-20(10-16-24)17-18-26(32,27(28,29)30)22-11-13-23(14-12-22)31(19-21-7-8-21)38(35,36)25-5-3-2-4-6-25/h2-6,9-16,21,32H,7-8,19H2,1H3 NMMZNDAQGGNURI-UHFFFAOYSA-N 50390765 CHEMBL2070464 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390765&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24767795 160869848 CHEMBL2070464 ZINC84690535 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218087 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1cc(Cl)ccc1Cl InChI=1S/C26H22Cl2F3NO3S/c1-18(2)17-32(36(34,35)24-16-21(27)10-13-23(24)28)22-11-8-20(9-12-22)25(33,26(29,30)31)15-14-19-6-4-3-5-7-19/h3-13,16,18,33H,17H2,1-2H3 OPWASPRJSUBIAP-UHFFFAOYSA-N 50390743 CHEMBL2070366 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042647 160869826 CHEMBL2070366 ZINC84687790 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218088 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC1CCC1)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C28H26F3NO5S2/c1-38(34,35)25-16-10-21(11-17-25)18-19-27(33,28(29,30)31)23-12-14-24(15-13-23)32(20-22-6-5-7-22)39(36,37)26-8-3-2-4-9-26/h2-4,8-17,22,33H,5-7,20H2,1H3 AQIOHOLALGMEGV-UHFFFAOYSA-N 50390767 CHEMBL2070465 Oxysterols receptor LXR-beta 7000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390767&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70682550 160869850 CHEMBL2070465 ZINC84690993 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218089 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C27H23F3N2O3S/c1-20(2)19-32(36(34,35)25-10-6-9-22(17-25)18-31)24-13-11-23(12-14-24)26(33,27(28,29)30)16-15-21-7-4-3-5-8-21/h3-14,17,20,33H,19H2,1-2H3 UPBQKZKPZNVPRI-UHFFFAOYSA-N 50390742 CHEMBL2070365 Oxysterols receptor LXR-beta 300 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042616 160869825 CHEMBL2070365 ZINC84687788 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218090 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(C)cc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F3NO3S/c1-20(2)19-31(35(33,34)25-7-5-4-6-8-25)24-15-13-23(14-16-24)26(32,27(28,29)30)18-17-22-11-9-21(3)10-12-22/h4-16,20,32H,19H2,1-3H3 HOKWHENHZPOIMO-UHFFFAOYSA-N 50390749 CHEMBL2070448 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390749&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042570 160869832 CHEMBL2070448 ZINC84709563 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218091 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cncn1C)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C24H24F3N3O3S/c1-18(2)16-30(34(32,33)22-7-5-4-6-8-22)20-11-9-19(10-12-20)23(31,24(25,26)27)14-13-21-15-28-17-29(21)3/h4-12,15,17-18,31H,16H2,1-3H3 WIPLZYJMGYWIBT-UHFFFAOYSA-N 50390739 CHEMBL2070362 Oxysterols receptor LXR-beta 5100 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70688857 160869822 CHEMBL2070362 ZINC84687457 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218092 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(F)cc1F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C26H22F5NO3S/c1-18(2)17-32(36(34,35)23-6-4-3-5-7-23)22-12-9-20(10-13-22)25(33,26(29,30)31)15-14-19-8-11-21(27)16-24(19)28/h3-13,16,18,33H,17H2,1-2H3 YDKXCKPEVZQWEP-UHFFFAOYSA-N 50390751 CHEMBL2070450 Oxysterols receptor LXR-beta 800 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042586 160869834 CHEMBL2070450 ZINC84710437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218093 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccnc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C25H23F3N2O3S/c1-19(2)18-30(34(32,33)23-8-4-3-5-9-23)22-12-10-21(11-13-22)24(31,25(26,27)28)15-14-20-7-6-16-29-17-20/h3-13,16-17,19,31H,18H2,1-2H3 YMCZPIAWBPMWLT-UHFFFAOYSA-N 50390738 CHEMBL2070361 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042611 160869821 CHEMBL2070361 ZINC84687455 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218094 CCCCc1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C30H32F3NO3S/c1-4-5-9-24-12-14-25(15-13-24)20-21-29(35,30(31,32)33)26-16-18-27(19-17-26)34(22-23(2)3)38(36,37)28-10-7-6-8-11-28/h6-8,10-19,23,35H,4-5,9,22H2,1-3H3 XKVLTCFSICEGEB-UHFFFAOYSA-N 50390750 CHEMBL2070449 Oxysterols receptor LXR-beta 3500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70695140 160869833 CHEMBL2070449 ZINC84709567 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218095 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CCC(F)(F)F)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C26H21F6NO5S2/c1-39(35,36)22-13-7-19(8-14-22)15-16-24(34,26(30,31)32)20-9-11-21(12-10-20)33(18-17-25(27,28)29)40(37,38)23-5-3-2-4-6-23/h2-14,34H,17-18H2,1H3 ABXFBIHMTMSADH-UHFFFAOYSA-N 50390764 CHEMBL2070462 Oxysterols receptor LXR-beta 4000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390764&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70684639 160869847 CHEMBL2070462 ZINC84690268 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218096 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H23F6NO3S/c1-19(2)18-34(38(36,37)24-9-4-3-5-10-24)23-13-11-21(12-14-23)25(35,27(31,32)33)16-15-20-7-6-8-22(17-20)26(28,29)30/h3-14,17,19,35H,18H2,1-2H3 IPVOYRALYXDGRZ-UHFFFAOYSA-N 50390745 CHEMBL2070368 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042645 160869828 CHEMBL2070368 ZINC84687794 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218097 CC(C)(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C28H28F3NO5S2/c1-26(2,3)20-32(39(36,37)25-8-6-5-7-9-25)23-14-12-22(13-15-23)27(33,28(29,30)31)19-18-21-10-16-24(17-11-21)38(4,34)35/h5-17,33H,20H2,1-4H3 ZATNJKHDTLHDQN-UHFFFAOYSA-N 50390766 CHEMBL2070463 Oxysterols receptor LXR-beta 6000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390766&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70686782 160869849 CHEMBL2070463 ZINC84690270 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218098 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(Cl)cc1)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C27H22ClF3N2O3S/c1-19(2)18-33(37(35,36)25-5-3-4-21(16-25)17-32)24-12-8-22(9-13-24)26(34,27(29,30)31)15-14-20-6-10-23(28)11-7-20/h3-13,16,19,34H,18H2,1-2H3 DFDDEXIVIDCBJU-UHFFFAOYSA-N 50390744 CHEMBL2070367 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042593 160869827 CHEMBL2070367 ZINC84687792 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218099 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)C(O)=O)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N InChI=1S/C28H23F3N2O5S/c1-19(2)18-33(39(37,38)25-5-3-4-21(16-25)17-32)24-12-10-23(11-13-24)27(36,28(29,30)31)15-14-20-6-8-22(9-7-20)26(34)35/h3-13,16,19,36H,18H2,1-2H3,(H,34,35) BDTIEODGWNQJHA-UHFFFAOYSA-N 50390762 CHEMBL2070460 Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390762&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70693094 160869845 CHEMBL2070460 ZINC84690525 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218100 COc1cccc(c1)C#CC(O)(c1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C27H26F3NO4S/c1-20(2)19-31(36(33,34)25-10-5-4-6-11-25)23-14-12-22(13-15-23)26(32,27(28,29)30)17-16-21-8-7-9-24(18-21)35-3/h4-15,18,20,32H,19H2,1-3H3 WGCDCIPOZNKVON-UHFFFAOYSA-N 50390769 CHEMBL2070370 Oxysterols receptor LXR-beta 1000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390769&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70697169 160869852 CHEMBL2070370 ZINC84690740 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218101 CS(=O)(=O)c1ccc(cc1)C#CC(O)(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C25H19F6NO5S2/c1-38(34,35)21-13-7-18(8-14-21)15-16-23(33,25(29,30)31)19-9-11-20(12-10-19)32(17-24(26,27)28)39(36,37)22-5-3-2-4-6-22/h2-14,33H,17H2,1H3 KWVKCBHTUNENFK-UHFFFAOYSA-N 50390763 CHEMBL2070461 Oxysterols receptor LXR-beta 9000 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390763&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 70690947 160869846 CHEMBL2070461 ZINC84690527 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50218102 CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccc(cc1)C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H23F6NO3S/c1-19(2)18-34(38(36,37)24-6-4-3-5-7-24)23-14-12-21(13-15-23)25(35,27(31,32)33)17-16-20-8-10-22(11-9-20)26(28,29)30/h3-15,19,35H,18H2,1-2H3 FAEPYFWSINNSSR-UHFFFAOYSA-N 50390746 CHEMBL2070369 Oxysterols receptor LXR-beta 2500 ChEMBL 10.1016/j.bmcl.2012.07.048 10.7270/Q2PR7X24 22901900 Jiao, X; Kopecky, DJ; Fisher, B; Piper, DE; Labelle, M; McKendry, S; Harrison, M; Jones, S; Jaen, J; Shiau, AK; Escaron, P; Danao, J; Chai, A; Coward, P; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50390746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50390746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042583 160869829 CHEMBL2070369 ZINC84690738 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50214764 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 4.7 ChEMBL 10.1021/jm101063h 10.7270/Q208668Q 21218783 Patch, RJ; Searle, LL; Kim, AJ; De, D; Zhu, X; Askari, HB; O'Neill, JC; Abad, MC; Rentzeperis, D; Liu, J; Kemmerer, M; Lin, L; Kasturi, J; Geisler, JG; Lenhard, JM; Player, MR; Gaul, MD Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50214768 COc1cc(C=C2SC(O)=NC2=O)ccc1Oc1ccc(cc1C(F)(F)F)C#N InChI=1S/C19H11F3N2O4S/c1-27-15-7-10(8-16-17(25)24-18(26)29-16)2-5-14(15)28-13-4-3-11(9-23)6-12(13)19(20,21)22/h2-8H,1H3,(H,24,25,26) OBBIOCQFTMNSJI-UHFFFAOYSA-N 50336730 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-trifluoromethylbenzonitrile::CHEMBL1671971 Oxysterols receptor LXR-beta >8300 ChEMBL 10.1021/jm101063h 10.7270/Q208668Q 21218783 Patch, RJ; Searle, LL; Kim, AJ; De, D; Zhu, X; Askari, HB; O'Neill, JC; Abad, MC; Rentzeperis, D; Liu, J; Kemmerer, M; Lin, L; Kasturi, J; Geisler, JG; Lenhard, JM; Player, MR; Gaul, MD Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336730&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46916268 125086832 CHEMBL1671971 ZINC66066336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50214784 COc1cc(C=C2SC(O)=NC2=O)ccc1Oc1ccc(cc1C(F)(F)F)C#N InChI=1S/C19H11F3N2O4S/c1-27-15-7-10(8-16-17(25)24-18(26)29-16)2-5-14(15)28-13-4-3-11(9-23)6-12(13)19(20,21)22/h2-8H,1H3,(H,24,25,26) OBBIOCQFTMNSJI-UHFFFAOYSA-N 50336730 4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy]-3-trifluoromethylbenzonitrile::CHEMBL1671971 Oxysterols receptor LXR-beta >8300 ChEMBL 10.1021/jm101063h 10.7270/Q208668Q 21218783 Patch, RJ; Searle, LL; Kim, AJ; De, D; Zhu, X; Askari, HB; O'Neill, JC; Abad, MC; Rentzeperis, D; Liu, J; Kemmerer, M; Lin, L; Kasturi, J; Geisler, JG; Lenhard, JM; Player, MR; Gaul, MD Johnson & Johnson Pharmaceutical Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336730&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46916268 125086832 CHEMBL1671971 ZINC66066336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216034 CCOCCn1cccc1C(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C23H25F3N2O3S/c1-3-31-17-16-28-15-7-10-21(28)22(23(24,25)26)18-11-13-19(14-12-18)27(2)32(29,30)20-8-5-4-6-9-20/h4-15,22H,3,16-17H2,1-2H3 QSIMLIBNOBVYGV-UHFFFAOYSA-N 50380070 CHEMBL2012768 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 21943465 160859153 CHEMBL2012768 ZINC84603341 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216038 CN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C16H13F6NO3S/c1-23(27(25,26)13-5-3-2-4-6-13)12-9-7-11(8-10-12)14(24,15(17,18)19)16(20,21)22/h2-10,24H,1H3 CNVKZYLQZYULJV-UHFFFAOYSA-N 50179869 CHEMBL203682::N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-benzenesulfonamide Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179869&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 0KS 4DK7 10112384 104065016 CHEMBL203682 ZINC01906924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216040 CCOCCn1cccc1C(O)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C23H25F3N2O4S/c1-3-32-17-16-28-15-7-10-21(28)22(29,23(24,25)26)18-11-13-19(14-12-18)27(2)33(30,31)20-8-5-4-6-9-20/h4-15,29H,3,16-17H2,1-2H3 RBXKJGOLBVSGDR-UHFFFAOYSA-N 50380069 CHEMBL2012767 Oxysterols receptor LXR-beta 1500 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380069&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 21943462 160859152 CHEMBL2012767 ZINC84603336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216041 COC(c1cccn1Cc1ccccc1)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C27H25F3N2O3S/c1-31(36(33,34)24-12-7-4-8-13-24)23-17-15-22(16-18-23)26(35-2,27(28,29)30)25-14-9-19-32(25)20-21-10-5-3-6-11-21/h3-19H,20H2,1-2H3 XZRPCTFVPDYGTL-UHFFFAOYSA-N 50380065 CHEMBL2012763 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042622 160859148 CHEMBL2012763 ZINC84605089 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216042 CN(c1ccc(cc1)C(O)(c1cccn1Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C26H23F3N2O3S/c1-30(35(33,34)23-11-6-3-7-12-23)22-16-14-21(15-17-22)25(32,26(27,28)29)24-13-8-18-31(24)19-20-9-4-2-5-10-20/h2-18,32H,19H2,1H3 NSXAZYXFYXSEQK-UHFFFAOYSA-N 50380064 CHEMBL2012762 Oxysterols receptor LXR-beta 800 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380064&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57404459 160859147 CHEMBL2012762 ZINC84603066 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216043 COCCn1cccc1C(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C22H23F3N2O3S/c1-26(31(28,29)19-7-4-3-5-8-19)18-12-10-17(11-13-18)21(22(23,24)25)20-9-6-14-27(20)15-16-30-2/h3-14,21H,15-16H2,1-2H3 SAIJBWDHHOMPIR-UHFFFAOYSA-N 50380068 CHEMBL2012766 Oxysterols receptor LXR-beta 800 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380068&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042589 160859151 CHEMBL2012766 ZINC84605101 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216044 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216047 COCCn1cccc1C(OC)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C23H25F3N2O4S/c1-27(33(29,30)20-8-5-4-6-9-20)19-13-11-18(12-14-19)22(32-3,23(24,25)26)21-10-7-15-28(21)16-17-31-2/h4-15H,16-17H2,1-3H3 GBXFIRKYLMIFBA-UHFFFAOYSA-N 50380067 CHEMBL2012765 Oxysterols receptor LXR-beta 900 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380067&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 22042635 160859150 CHEMBL2012765 ZINC84605098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50216049 COCCn1cccc1C(O)(c1ccc(cc1)N(C)S(=O)(=O)c1ccccc1)C(F)(F)F InChI=1S/C22H23F3N2O4S/c1-26(32(29,30)19-7-4-3-5-8-19)18-12-10-17(11-13-18)21(28,22(23,24)25)20-9-6-14-27(20)15-16-31-2/h3-14,28H,15-16H2,1-2H3 YNUCWQDMZHYFEC-UHFFFAOYSA-N 50380066 CHEMBL2012764 Oxysterols receptor LXR-beta 1800 ChEMBL 10.1016/j.bmcl.2012.02.028 10.7270/Q2M61M77 22406115 Kopecky, DJ; Jiao, XY; Fisher, B; McKendry, S; Labelle, M; Piper, DE; Coward, P; Shiau, AK; Escaron, P; Danao, J; Chai, A; Jaen, J; Kayser, F Amgen Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 0KT 4DK8 22042567 160859149 CHEMBL2012764 ZINC84605093 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219627 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 90 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219628 CN1c2ccc(cc2CCc2ccccc2C1=O)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H15F6NO2/c1-26-15-9-8-13(17(28,18(20,21)22)19(23,24)25)10-12(15)7-6-11-4-2-3-5-14(11)16(26)27/h2-5,8-10,28H,6-7H2,1H3 PCNFJMCIOJDDMB-UHFFFAOYSA-N 50396597 CHEMBL2171908 Oxysterols receptor LXR-beta 260 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396597&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71457062 163345621 CHEMBL2171908 ZINC95556150 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219684 CN1c2ccc(cc2Oc2ccccc2C1=O)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H11F6NO3/c1-24-11-7-6-9(15(26,16(18,19)20)17(21,22)23)8-13(11)27-12-5-3-2-4-10(12)14(24)25/h2-8,26H,1H3 ZBGOKZJTMPLHNL-UHFFFAOYSA-N 50396598 CHEMBL2171907 Oxysterols receptor LXR-beta 2700 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396598&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71455271 163345622 CHEMBL2171907 ZINC95555210 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219685 CN1c2ccc(cc2C(=C)c2ccccc2C1=O)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C19H13F6NO2/c1-10-12-5-3-4-6-13(12)16(27)26(2)15-8-7-11(9-14(10)15)17(28,18(20,21)22)19(23,24)25/h3-9,28H,1H2,2H3 KHGLCRLWTRDGEJ-UHFFFAOYSA-N 50396596 CHEMBL2171909 Oxysterols receptor LXR-beta 770 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396596&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71462454 163345620 CHEMBL2171909 ZINC95556145 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219691 CN1c2ccc(N)cc2C(=C)c2ccccc2C1=O InChI=1S/C16H14N2O/c1-10-12-5-3-4-6-13(12)16(19)18(2)15-8-7-11(17)9-14(10)15/h3-9H,1,17H2,2H3 GLKYAQGIJQCRPH-UHFFFAOYSA-N 50396602 CHEMBL2169907 Oxysterols receptor LXR-beta 27000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396602&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71457060 163345626 CHEMBL2169907 ZINC95556504 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219722 CCc1ccc2N(C)C(=O)c3ccccc3C(=C)c2c1 InChI=1S/C18H17NO/c1-4-13-9-10-17-16(11-13)12(2)14-7-5-6-8-15(14)18(20)19(17)3/h5-11H,2,4H2,1,3H3 BGVIGGHVNBLYIS-UHFFFAOYSA-N 50396593 CHEMBL2171912 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396593&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71455272 163345617 CHEMBL2171912 ZINC95554941 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219723 C[n+]1c2ccc(cc2c([CH2-])c2ccccc2c1=O)[N+]([O-])=O InChI=1S/C16H12N2O3/c1-10-12-5-3-4-6-13(12)16(19)17(2)15-8-7-11(18(20)21)9-14(10)15/h3-9H,1H2,2H3 CWBGTRWGHOYBSM-UHFFFAOYSA-N 50396603 CHEMBL2171901 Oxysterols receptor LXR-beta 13000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396603&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71462452 163345627 CHEMBL2171901 ZINC95557666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219724 CN1c2ccc(C)cc2C(=C)c2ccccc2C1=O InChI=1S/C17H15NO/c1-11-8-9-16-15(10-11)12(2)13-6-4-5-7-14(13)17(19)18(16)3/h4-10H,2H2,1,3H3 XAUVXJYDZFIUQS-UHFFFAOYSA-N 50396594 CHEMBL2171911 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396594&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71451730 163345618 CHEMBL2171911 ZINC95556957 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219725 CN1c2ccc(cc2C(=C)c2ccccc2C1=O)C(C)(C)C InChI=1S/C20H21NO/c1-13-15-8-6-7-9-16(15)19(22)21(5)18-11-10-14(12-17(13)18)20(2,3)4/h6-12H,1H2,2-5H3 NNOHGGBPJHNYNA-UHFFFAOYSA-N 50396589 CHEMBL2171916 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396589&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71462456 163345613 CHEMBL2171916 ZINC95556181 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219726 CCc1ccc2N(C)C(=O)c3cc(ccc3C(=C)c2c1)-c1ccc(CC(O)=O)cc1 InChI=1S/C26H23NO3/c1-4-17-7-12-24-22(13-17)16(2)21-11-10-20(15-23(21)26(30)27(24)3)19-8-5-18(6-9-19)14-25(28)29/h5-13,15H,2,4,14H2,1,3H3,(H,28,29) CHDXIUFTJYWUOY-UHFFFAOYSA-N 50396605 CHEMBL2171829 Oxysterols receptor LXR-beta 15000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396605&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71451721 163345629 CHEMBL2171829 C03768 ZINC95553835 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219727 CN1c2ccc(cc2C(=C)c2ccccc2C1=O)C(C)=O InChI=1S/C18H15NO2/c1-11-14-6-4-5-7-15(14)18(21)19(3)17-9-8-13(12(2)20)10-16(11)17/h4-10H,1H2,2-3H3 XLPHZTCBPKMHIB-UHFFFAOYSA-N 50396604 CHEMBL2171905 Oxysterols receptor LXR-beta 7500 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396604&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71457061 163345628 CHEMBL2171905 ZINC95556183 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219728 CC(C)c1ccc2N(C)C(=O)c3ccccc3C(=C)c2c1 InChI=1S/C19H19NO/c1-12(2)14-9-10-18-17(11-14)13(3)15-7-5-6-8-16(15)19(21)20(18)4/h5-12H,3H2,1-2,4H3 RUOLLTVTQPJIRV-UHFFFAOYSA-N 50396590 CHEMBL2171915 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396590&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71462455 163345614 CHEMBL2171915 ZINC95555289 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219729 CN1c2ccc(cc2C(=C)c2ccccc2C1=O)C(O)=O InChI=1S/C17H13NO3/c1-10-12-5-3-4-6-13(12)16(19)18(2)15-8-7-11(17(20)21)9-14(10)15/h3-9H,1H2,2H3,(H,20,21) WFEXZKAPAGWJSP-UHFFFAOYSA-N 50396599 CHEMBL2171904 Oxysterols receptor LXR-beta 26000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396599&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71458919 163345623 CHEMBL2171904 ZINC95557373 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219730 CCc1ccc2N(C)C(=O)c3cc(ccc3C(=C)c2c1)-c1cccc(CC(O)=O)c1 InChI=1S/C26H23NO3/c1-4-17-8-11-24-22(13-17)16(2)21-10-9-20(15-23(21)26(30)27(24)3)19-7-5-6-18(12-19)14-25(28)29/h5-13,15H,2,4,14H2,1,3H3,(H,28,29) XUCFBCPZTLKOBX-UHFFFAOYSA-N 50396606 CHEMBL2171828 Oxysterols receptor LXR-beta 27000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396606&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71460723 163345630 CHEMBL2171828 ZINC95553769 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219731 CCCCCCCCCCCCc1ccc2N(C)C(=O)c3ccccc3C(=C)c2c1 InChI=1S/C28H37NO/c1-4-5-6-7-8-9-10-11-12-13-16-23-19-20-27-26(21-23)22(2)24-17-14-15-18-25(24)28(30)29(27)3/h14-15,17-21H,2,4-13,16H2,1,3H3 CVBOKWXYUANEIV-UHFFFAOYSA-N 50396591 CHEMBL2171914 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396591&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71460728 163345615 CHEMBL2171914 ZINC95555917 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219732 CN1c2ccc(CO)cc2C(=C)c2ccccc2C1=O InChI=1S/C17H15NO2/c1-11-13-5-3-4-6-14(13)17(20)18(2)16-8-7-12(10-19)9-15(11)16/h3-9,19H,1,10H2,2H3 OXRCUCWHMWYTJK-UHFFFAOYSA-N 50396600 CHEMBL2171903 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396600&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71462453 163345624 CHEMBL2171903 ZINC95552300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219733 CCc1ccc2N(C)C(=O)c3cc(ccc3C(=C)c2c1)-c1ccc(cc1)C(O)=O InChI=1S/C25H21NO3/c1-4-16-5-12-23-21(13-16)15(2)20-11-10-19(14-22(20)24(27)26(23)3)17-6-8-18(9-7-17)25(28)29/h5-14H,2,4H2,1,3H3,(H,28,29) JVGCIYMMOVAJFX-UHFFFAOYSA-N 50396607 CHEMBL2171827 Oxysterols receptor LXR-beta 9500 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396607&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71460722 163345631 CHEMBL2171827 ZINC95556244 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50219734 CCCCCCc1ccc2N(C)C(=O)c3ccccc3C(=C)c2c1 InChI=1S/C22H25NO/c1-4-5-6-7-10-17-13-14-21-20(15-17)16(2)18-11-8-9-12-19(18)22(24)23(21)3/h8-9,11-15H,2,4-7,10H2,1,3H3 IAVVWWBAVCVMLO-UHFFFAOYSA-N 50396592 CHEMBL2171913 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/jm3002394 10.7270/Q2NV9KCH 22873709 Aoyama, A; Endo-Umeda, K; Kishida, K; Ohgane, K; Noguchi-Yachide, T; Aoyama, H; Ishikawa, M; Miyachi, H; Makishima, M; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396592&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71451731 163345616 CHEMBL2171913 ZINC95556195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50243471 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 85 ChEMBL 10.1016/j.bmcl.2014.09.053 10.7270/Q2S46TKZ 25305688 Gege, C; Schlüter, T; Hoffmann, T Phenex Pharmaceuticals AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250437 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3 JLPURTXCSILYLW-UHFFFAOYSA-N 50034775 CHEMBL3360975::US10543183, Compound 38::US10945978, Compound 38 Oxysterols receptor LXR-beta 250 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652 4RAK 59251511 313066503 CHEMBL3360975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250438 CC(C)(O)c1cn(c(Cc2ccccc2Cl)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C26H25ClN2O3S/c1-26(2,30)24-17-29(25(28-24)16-20-7-4-5-10-23(20)27)21-13-11-18(12-14-21)19-8-6-9-22(15-19)33(3,31)32/h4-15,17,30H,16H2,1-3H3 MVEYCHUAHRZQOD-UHFFFAOYSA-N 50034776 CHEMBL3360974 Oxysterols receptor LXR-beta 66 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034776&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251553 313066504 CHEMBL3360974 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250439 CC(C)(O)c1cn(c(Cc2ccccc2C(F)(F)F)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C27H25F3N2O3S/c1-26(2,33)24-17-32(25(31-24)16-20-7-4-5-10-23(20)27(28,29)30)21-13-11-18(12-14-21)19-8-6-9-22(15-19)36(3,34)35/h4-15,17,33H,16H2,1-3H3 LYVSLMPYMYETMJ-UHFFFAOYSA-N 50034777 CHEMBL3360973 Oxysterols receptor LXR-beta 140 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034777&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251456 313066505 CHEMBL3360973 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250440 CC(C)(O)c1cn(c(n1)-c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C25H22Cl2N2O3S/c1-25(2,30)22-15-29(24(28-22)23-20(26)8-5-9-21(23)27)18-12-10-16(11-13-18)17-6-4-7-19(14-17)33(3,31)32/h4-15,30H,1-3H3 LZUBEQUFSVAVEB-UHFFFAOYSA-N 50034778 CHEMBL3360972 Oxysterols receptor LXR-beta 670 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034778&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251431 313066506 CHEMBL3360972 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250441 CC(C)(O)c1cn(c(n1)-c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C25H23ClN2O3S/c1-25(2,29)23-16-28(24(27-23)21-9-4-5-10-22(21)26)19-13-11-17(12-14-19)18-7-6-8-20(15-18)32(3,30)31/h4-16,29H,1-3H3 JDYKELQKNHNOIN-UHFFFAOYSA-N 50034779 CHEMBL3360971 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034779&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251592 313066507 CHEMBL3360971 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250442 CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-n1cc(nc1-c1ccccc1Cl)C(F)(F)F InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-16(13-18)15-9-11-17(12-10-15)29-14-21(23(25,26)27)28-22(29)19-7-2-3-8-20(19)24/h2-14H,1H3 IWVRHURFJVBGSF-UHFFFAOYSA-N 50034780 CHEMBL3360970 Oxysterols receptor LXR-beta 61 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034780&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251295 313066508 CHEMBL3360970 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250443 CC(C)(O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl InChI=1S/C23H21ClN2O3S2/c1-23(2,27)22-14-19(26(25-22)18-10-5-4-9-17(18)24)21-12-11-20(30-21)15-7-6-8-16(13-15)31(3,28)29/h4-14,27H,1-3H3 SALZQMSOIKCKNM-UHFFFAOYSA-N 50034781 CHEMBL3360969 Oxysterols receptor LXR-beta 620 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034781&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59631866 313066509 CHEMBL3360969 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250444 COC(=O)c1cc(-c2ccc(s2)-c2cccc(c2)S(C)(=O)=O)n(n1)-c1ccccc1Cl InChI=1S/C22H17ClN2O4S2/c1-29-22(26)17-13-19(25(24-17)18-9-4-3-8-16(18)23)21-11-10-20(30-21)14-6-5-7-15(12-14)31(2,27)28/h3-13H,1-2H3 ZXTOKWKHXXGVMT-UHFFFAOYSA-N 50034782 CHEMBL3360968 Oxysterols receptor LXR-beta 64 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034782&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59631939 313066510 CHEMBL3360968 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250445 CS(=O)(=O)c1cccc(c1)-c1cccc(c1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-9-5-7-16(13-18)15-6-4-8-17(12-15)21-14-22(23(25,26)27)28-29(21)20-11-3-2-10-19(20)24/h2-14H,1H3 VOOZJAGZCXOELE-UHFFFAOYSA-N 50034783 CHEMBL3360967 Oxysterols receptor LXR-beta 230 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034783&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59633156 313066511 CHEMBL3360967 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250446 CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-17(13-18)15-9-11-16(12-10-15)21-14-22(23(25,26)27)28-29(21)20-8-3-2-7-19(20)24/h2-14H,1H3 STNGIHCHDLCYEV-UHFFFAOYSA-N 50034784 CHEMBL3360966 Oxysterols receptor LXR-beta 49 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034784&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59632480 313066512 CHEMBL3360966 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250447 CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1-c1ccccc1C(F)(F)F)C(F)(F)F InChI=1S/C22H14F6N2O2S2/c1-34(31,32)14-6-4-5-13(11-14)18-9-10-19(33-18)17-12-20(22(26,27)28)29-30(17)16-8-3-2-7-15(16)21(23,24)25/h2-12H,1H3 XQWURCYLMCTAFE-UHFFFAOYSA-N 50034785 CHEMBL3360965 Oxysterols receptor LXR-beta 68 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034785&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59632565 313066513 CHEMBL3360965 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250448 CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F InChI=1S/C21H14ClF3N2O2S2/c1-31(28,29)14-6-4-5-13(11-14)18-9-10-19(30-18)17-12-20(21(23,24)25)26-27(17)16-8-3-2-7-15(16)22/h2-12H,1H3 DIRKHQVAVLSYMA-UHFFFAOYSA-N 50034786 CHEMBL3360964 Oxysterols receptor LXR-beta 110 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034786&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59632482 313066514 CHEMBL3360964 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250449 CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1Cc1ccc(F)cc1F)C(F)(F)F InChI=1S/C22H15F5N2O2S2/c1-33(30,31)16-4-2-3-13(9-16)19-7-8-20(32-19)18-11-21(22(25,26)27)28-29(18)12-14-5-6-15(23)10-17(14)24/h2-11H,12H2,1H3 KMTFPMRUPSWRTQ-UHFFFAOYSA-N 50034788 CHEMBL3360963 Oxysterols receptor LXR-beta 14 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034788&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 68655604 313066515 CHEMBL3360963 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250450 Cc1cc(CC(O)=O)ccc1-c1ccc(s1)-c1cc(c(C#N)c(=O)n1Cc1ccc(F)cc1F)C(F)(F)F InChI=1S/C27H17F5N2O3S/c1-14-8-15(9-25(35)36)2-5-18(14)23-6-7-24(38-23)22-11-20(27(30,31)32)19(12-33)26(37)34(22)13-16-3-4-17(28)10-21(16)29/h2-8,10-11H,9,13H2,1H3,(H,35,36) WZMZHHPXANSLBG-UHFFFAOYSA-N 50034789 CHEMBL3360962 Oxysterols receptor LXR-beta 320 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034789&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 66797441 313066516 CHEMBL3360962 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250451 Fc1ccc(Cn2c(cc(c(C#N)c2=O)C(F)(F)F)-c2ccc(Oc3ccccc3)cc2)c(F)c1 InChI=1S/C26H15F5N2O2/c27-18-9-6-17(23(28)12-18)15-33-24(13-22(26(29,30)31)21(14-32)25(33)34)16-7-10-20(11-8-16)35-19-4-2-1-3-5-19/h1-13H,15H2 SWBBNSPWRVCYAE-UHFFFAOYSA-N 50034790 CHEMBL3360961 Oxysterols receptor LXR-beta 20 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034790&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11496708 313066517 CHEMBL3360961 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250452 CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(c(C#N)c(=O)n1Cc1ccc(F)cc1F)C(F)(F)F InChI=1S/C25H15F5N2O3S2/c1-37(34,35)17-4-2-3-14(9-17)22-7-8-23(36-22)21-11-19(25(28,29)30)18(12-31)24(33)32(21)13-15-5-6-16(26)10-20(15)27/h2-11H,13H2,1H3 WPGIFTVVEKGIGJ-UHFFFAOYSA-N 50034791 CHEMBL3360960 Oxysterols receptor LXR-beta 2.0 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034791&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59726531 313066518 CHEMBL3360960 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50250453 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 140 ChEMBL 10.1016/j.bmcl.2014.11.029 10.7270/Q2154JN9 25435151 Kick, E; Martin, R; Xie, Y; Flatt, B; Schweiger, E; Wang, TL; Busch, B; Nyman, M; Gu, XH; Yan, G; Wagner, B; Nanao, M; Nguyen, L; Stout, T; Plonowski, A; Schulman, I; Ostrowski, J; Kirchgessner, T; Wexler, R; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50252745 CC(C)CN(Cc1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C25H29NO4S2/c1-20(2)17-26(32(29,30)19-22-7-5-4-6-8-22)18-21-9-11-23(12-10-21)24-13-15-25(16-14-24)31(3,27)28/h4-16,20H,17-19H2,1-3H3 PLZDXNPMOQHWFC-UHFFFAOYSA-N 50012130 CHEMBL3263710 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.10.037 10.7270/Q2125V8F 25453817 van Niel, MB; Fauber, BP; Cartwright, M; Gaines, S; Killen, JC; René, O; Ward, SI; de Leon Boenig, G; Deng, Y; Eidenschenk, C; Everett, C; Gancia, E; Ganguli, A; Gobbi, A; Hawkins, J; Johnson, AR; Kiefer, JR; La, H; Lockey, P; Norman, M; Ouyang, W; Qin, A; Wakes, N; Waszkowycz, B; Wong, H Argenta Discovery Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012130&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71622396 242058056 CHEMBL3263710 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50252775 CC(C)CN(Cc1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(NC2CCN(CC2)S(C)(=O)=O)cc1 InChI=1S/C24H32F3N3O4S2/c1-18(2)16-30(17-19-6-4-5-7-23(19)24(25,26)27)36(33,34)22-10-8-20(9-11-22)28-21-12-14-29(15-13-21)35(3,31)32/h4-11,18,21,28H,12-17H2,1-3H3 RQGOFVOEBXQQJA-UHFFFAOYSA-N 50035907 CHEMBL3361050 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.10.037 10.7270/Q2125V8F 25453817 van Niel, MB; Fauber, BP; Cartwright, M; Gaines, S; Killen, JC; René, O; Ward, SI; de Leon Boenig, G; Deng, Y; Eidenschenk, C; Everett, C; Gancia, E; Ganguli, A; Gobbi, A; Hawkins, J; Johnson, AR; Kiefer, JR; La, H; Lockey, P; Norman, M; Ouyang, W; Qin, A; Wakes, N; Waszkowycz, B; Wong, H Argenta Discovery Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035907&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 74762670 103943788 CHEMBL3361050 ZINC13740189 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50252776 CC(C)CN(c1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(NC2CCN(CC2)S(C)(=O)=O)cc1 InChI=1S/C23H30F3N3O4S2/c1-17(2)16-29(22-7-5-4-6-21(22)23(24,25)26)35(32,33)20-10-8-18(9-11-20)27-19-12-14-28(15-13-19)34(3,30)31/h4-11,17,19,27H,12-16H2,1-3H3 QRWSUSUONCKWOH-UHFFFAOYSA-N 50035908 CHEMBL3361051 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.10.037 10.7270/Q2125V8F 25453817 van Niel, MB; Fauber, BP; Cartwright, M; Gaines, S; Killen, JC; René, O; Ward, SI; de Leon Boenig, G; Deng, Y; Eidenschenk, C; Everett, C; Gancia, E; Ganguli, A; Gobbi, A; Hawkins, J; Johnson, AR; Kiefer, JR; La, H; Lockey, P; Norman, M; Ouyang, W; Qin, A; Wakes, N; Waszkowycz, B; Wong, H Argenta Discovery Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035908&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 90200534 103943789 CHEMBL3361051 ZINC13740195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50252790 CC(C)CN(c1ccc(F)cc1)S(=O)(=O)c1ccc(OC2CCN(CC2)S(C)(=O)=O)cc1 InChI=1S/C22H29FN2O5S2/c1-17(2)16-25(19-6-4-18(23)5-7-19)32(28,29)22-10-8-20(9-11-22)30-21-12-14-24(15-13-21)31(3,26)27/h4-11,17,21H,12-16H2,1-3H3 OEVBZJRMGQUWSV-UHFFFAOYSA-N 50035915 CHEMBL3361058 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.10.037 10.7270/Q2125V8F 25453817 van Niel, MB; Fauber, BP; Cartwright, M; Gaines, S; Killen, JC; René, O; Ward, SI; de Leon Boenig, G; Deng, Y; Eidenschenk, C; Everett, C; Gancia, E; Ganguli, A; Gobbi, A; Hawkins, J; Johnson, AR; Kiefer, JR; La, H; Lockey, P; Norman, M; Ouyang, W; Qin, A; Wakes, N; Waszkowycz, B; Wong, H Argenta Discovery Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035915&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 76284182 313066780 CHEMBL3361058 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50252809 CC(C)CN(c1ccc(cc1)C#N)S(=O)(=O)c1ccc(OC2CCN(CC2)S(C)(=O)=O)cc1 InChI=1S/C23H29N3O5S2/c1-18(2)17-26(20-6-4-19(16-24)5-7-20)33(29,30)23-10-8-21(9-11-23)31-22-12-14-25(15-13-22)32(3,27)28/h4-11,18,22H,12-15,17H2,1-3H3 NTWWBXUIMFTACU-UHFFFAOYSA-N 50035918 CHEMBL3361061 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.10.037 10.7270/Q2125V8F 25453817 van Niel, MB; Fauber, BP; Cartwright, M; Gaines, S; Killen, JC; René, O; Ward, SI; de Leon Boenig, G; Deng, Y; Eidenschenk, C; Everett, C; Gancia, E; Ganguli, A; Gobbi, A; Hawkins, J; Johnson, AR; Kiefer, JR; La, H; Lockey, P; Norman, M; Ouyang, W; Qin, A; Wakes, N; Waszkowycz, B; Wong, H Argenta Discovery Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035918&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118526849 313066783 CHEMBL3361061 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50252810 CC(C)CN(Cc1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(OC2CCN(CC2)S(C)(=O)=O)cn1 InChI=1S/C23H30F3N3O5S2/c1-17(2)15-29(16-18-6-4-5-7-21(18)23(24,25)26)36(32,33)22-9-8-20(14-27-22)34-19-10-12-28(13-11-19)35(3,30)31/h4-9,14,17,19H,10-13,15-16H2,1-3H3 NQZVKYGHMFGQDB-UHFFFAOYSA-N 50035885 CHEMBL3361064 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.10.037 10.7270/Q2125V8F 25453817 van Niel, MB; Fauber, BP; Cartwright, M; Gaines, S; Killen, JC; René, O; Ward, SI; de Leon Boenig, G; Deng, Y; Eidenschenk, C; Everett, C; Gancia, E; Ganguli, A; Gobbi, A; Hawkins, J; Johnson, AR; Kiefer, JR; La, H; Lockey, P; Norman, M; Ouyang, W; Qin, A; Wakes, N; Waszkowycz, B; Wong, H Argenta Discovery Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035885&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118724654 313066757 CHEMBL3361064 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50248529 Cc1nc(c(Cl)n1-c1ccc(cc1-n1nncc1-c1ccc(OC(F)(F)F)cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C28H19ClF7N5O4S/c1-14-38-25(27(31,32)33)26(29)40(14)21-8-5-16(17-9-20(30)19(13-42)24(11-17)46(2,43)44)10-22(21)41-23(12-37-39-41)15-3-6-18(7-4-15)45-28(34,35)36/h3-12,42H,13H2,1-2H3 CVFPZOVMCUZTKC-UHFFFAOYSA-N 50032895 CHEMBL3342785 Oxysterols receptor LXR-beta 40 ChEMBL 10.1021/ml500403f 10.7270/Q2CJ8G28 25408828 Abdel-Magid, AF Therachem Research Medilab (India) Pvt. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032895&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 86297437 103941316 CHEMBL3342785 ZINC26944043 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50248530 Cc1nc(cn1-c1ccc(cc1-n1nncc1Cc1cccc(Cl)c1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C27H21ClF3N5O2S/c1-17-33-26(27(29,30)31)16-35(17)24-10-9-20(19-6-4-8-23(13-19)39(2,37)38)14-25(24)36-22(15-32-34-36)12-18-5-3-7-21(28)11-18/h3-11,13-16H,12H2,1-2H3 MTVNFTAROMBUMX-UHFFFAOYSA-N 50032896 CHEMBL3342786 Oxysterols receptor LXR-beta 651 ChEMBL 10.1021/ml500403f 10.7270/Q2CJ8G28 25408828 Abdel-Magid, AF Therachem Research Medilab (India) Pvt. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032896&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 90447465 103941317 CHEMBL3342786 ZINC26943363 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50248531 Cc1nc(cn1-c1c(F)cc(cc1-n1nncc1-c1ccc(Cl)cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C26H18ClF4N5O2S/c1-15-33-24(26(29,30)31)14-35(15)25-21(28)11-18(17-4-3-5-20(10-17)39(2,37)38)12-22(25)36-23(13-32-34-36)16-6-8-19(27)9-7-16/h3-14H,1-2H3 CVVFLZOBPHEBLZ-UHFFFAOYSA-N 50032897 CHEMBL3342787 Oxysterols receptor LXR-beta 110 ChEMBL 10.1021/ml500403f 10.7270/Q2CJ8G28 25408828 Abdel-Magid, AF Therachem Research Medilab (India) Pvt. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032897&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 90447258 313066254 CHEMBL3342787 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50248532 CC(C)c1nc(c(o1)-c1ccc(OC(F)(F)F)cc1)-c1cc(ccc1-n1cc(nc1C)C(F)(F)F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C32H26F7N3O5S/c1-16(2)30-41-28(29(46-30)18-5-8-21(9-6-18)47-32(37,38)39)22-11-19(20-12-24(33)23(15-43)26(13-20)48(4,44)45)7-10-25(22)42-14-27(31(34,35)36)40-17(42)3/h5-14,16,43H,15H2,1-4H3 NRSDWNVESRFSKT-UHFFFAOYSA-N 50032898 CHEMBL3342788 Oxysterols receptor LXR-beta 16 ChEMBL 10.1021/ml500403f 10.7270/Q2CJ8G28 25408828 Abdel-Magid, AF Therachem Research Medilab (India) Pvt. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032898&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 90447547 313066255 CHEMBL3342788 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50277458 CC(C)CN(Cc1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C25H29NO4S2/c1-20(2)17-26(32(29,30)19-22-7-5-4-6-8-22)18-21-9-11-23(12-10-21)24-13-15-25(16-14-24)31(3,27)28/h4-16,20H,17-19H2,1-3H3 PLZDXNPMOQHWFC-UHFFFAOYSA-N 50012130 CHEMBL3263710 Oxysterols receptor LXR-beta 2500 ChEMBL 10.1016/j.bmcl.2014.06.048 10.7270/Q2CR5W1Q 25017032 Fauber, BP; René, O; de Leon Boenig, G; Burton, B; Deng, Y; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; La, H; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Wang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012130&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71622396 242058056 CHEMBL3263710 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50277459 CC(C)CN(Cc1ccc(cc1)N1CCN(CC1)C(C)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C24H33N3O3S/c1-20(2)17-27(31(29,30)19-23-7-5-4-6-8-23)18-22-9-11-24(12-10-22)26-15-13-25(14-16-26)21(3)28/h4-12,20H,13-19H2,1-3H3 CYRKYCCPWKLCDV-UHFFFAOYSA-N 50050083 CHEMBL3317833::US9216988, 101 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.06.048 10.7270/Q2CR5W1Q 25017032 Fauber, BP; René, O; de Leon Boenig, G; Burton, B; Deng, Y; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; La, H; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Wang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3SX 4WQP 86346645 103947270 CHEMBL3317833 ZINC25965232 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50277460 CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C24H31N3O3S/c1-20(28)25-14-16-26(17-15-25)23-12-10-21(11-13-23)18-27(24-8-5-9-24)31(29,30)19-22-6-3-2-4-7-22/h2-4,6-7,10-13,24H,5,8-9,14-19H2,1H3 KIHDXHLXSMPQSN-UHFFFAOYSA-N 50050086 CHEMBL3317836::US9216988, 55 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.06.048 10.7270/Q2CR5W1Q 25017032 Fauber, BP; René, O; de Leon Boenig, G; Burton, B; Deng, Y; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; La, H; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Wang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050086&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 86690644 103947273 CHEMBL3317836 ZINC25965335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50277461 CC(C)N(Cc1ccc(cc1)N1CCN(CC1)C(C)=O)S(=O)(=O)Cc1ccccc1 InChI=1S/C23H31N3O3S/c1-19(2)26(30(28,29)18-22-7-5-4-6-8-22)17-21-9-11-23(12-10-21)25-15-13-24(14-16-25)20(3)27/h4-12,19H,13-18H2,1-3H3 QBHMBDZJVDBYGI-UHFFFAOYSA-N 50050087 CHEMBL3317840::US9216988, 50 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.06.048 10.7270/Q2CR5W1Q 25017032 Fauber, BP; René, O; de Leon Boenig, G; Burton, B; Deng, Y; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; La, H; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Wang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050087&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89659415 103947274 CHEMBL3317840 ZINC25965328 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50277462 CC(=O)N1CCN(CC1)c1ccc(CN(CC(F)(F)F)S(=O)(=O)Cc2ccccc2)cc1 InChI=1S/C22H26F3N3O3S/c1-18(29)26-11-13-27(14-12-26)21-9-7-19(8-10-21)15-28(17-22(23,24)25)32(30,31)16-20-5-3-2-4-6-20/h2-10H,11-17H2,1H3 MBOQHZCUORBTLA-UHFFFAOYSA-N 50050117 CHEMBL3317843::US9216988, 54 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2014.06.048 10.7270/Q2CR5W1Q 25017032 Fauber, BP; René, O; de Leon Boenig, G; Burton, B; Deng, Y; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; La, H; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Wang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050117&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 86690646 103947304 CHEMBL3317843 ZINC13747255 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50265756 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H11F10NO3S/c18-11-3-7-13(8-4-11)32(30,31)28(9-14(19,20)21)12-5-1-10(2-6-12)15(29,16(22,23)24)17(25,26)27/h1-8,29H,9H2 XCJCRDUPVLFMDD-UHFFFAOYSA-N 50444333 CHEMBL3094369 Oxysterols receptor LXR-beta 390 ChEMBL 10.1021/jm401901d 10.7270/Q2M0473Z 24502334 Fauber, BP; Magnuson, S Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50444333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50444333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 72722945 194942229 CHEMBL3094369 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50265757 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 160 ChEMBL 10.1021/jm401901d 10.7270/Q2M0473Z 24502334 Fauber, BP; Magnuson, S Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299887 CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccc(OC)cc2)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C28H29F3N2O6/c1-4-7-20-22(13-12-19-21(28(29,30)31)16-23(34)39-24(19)20)38-15-6-5-14-33-25(35)27(2,32-26(33)36)17-8-10-18(37-3)11-9-17/h8-13,16H,4-7,14-15H2,1-3H3,(H,32,36) ABUHBGNGKQNACH-UHFFFAOYSA-N 50064330 CHEMBL3403710 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064330&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44217616 313071266 CHEMBL3403710 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299888 CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccc(OC)c(OC)c2)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C29H31F3N2O7/c1-5-8-19-21(12-10-18-20(29(30,31)32)16-24(35)41-25(18)19)40-14-7-6-13-34-26(36)28(2,33-27(34)37)17-9-11-22(38-3)23(15-17)39-4/h9-12,15-16H,5-8,13-14H2,1-4H3,(H,33,37) WJDHPHKPELPXKW-UHFFFAOYSA-N 50064331 CHEMBL3403711 Oxysterols receptor LXR-beta 3000 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064331&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962948 313071267 CHEMBL3403711 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299889 CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccc3OCOc3c2)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C28H27F3N2O7/c1-3-6-18-20(10-8-17-19(28(29,30)31)14-23(34)40-24(17)18)37-12-5-4-11-33-25(35)27(2,32-26(33)36)16-7-9-21-22(13-16)39-15-38-21/h7-10,13-14H,3-6,11-12,15H2,1-2H3,(H,32,36) LTOQZEOGGXZELX-UHFFFAOYSA-N 50064332 CHEMBL3403712 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064332&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44217767 313071268 CHEMBL3403712 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299897 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 420 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299898 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)CSC1=O)C(F)(F)F InChI=1S/C23H26F3NO5S/c1-3-7-14-11-16-17(23(24,25)26)12-19(29)32-21(16)15(8-4-2)20(14)31-10-6-5-9-27-18(28)13-33-22(27)30/h11-12H,3-10,13H2,1-2H3 RLPKTOXVEGWOGJ-UHFFFAOYSA-N 50064381 CHEMBL3403686 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064381&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118729956 313071273 CHEMBL3403686 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299899 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)CN(C)C1=O)C(F)(F)F InChI=1S/C24H29F3N2O5/c1-4-8-15-12-17-18(24(25,26)27)13-20(31)34-22(17)16(9-5-2)21(15)33-11-7-6-10-29-19(30)14-28(3)23(29)32/h12-13H,4-11,14H2,1-3H3 KANFQBHREKEGNX-UHFFFAOYSA-N 50064380 CHEMBL3403687 Oxysterols receptor LXR-beta 1300 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064380&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962932 313071272 CHEMBL3403687 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299900 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)CCC1=O)C(F)(F)F InChI=1S/C24H28F3NO5/c1-3-7-15-13-17-18(24(25,26)27)14-21(31)33-23(17)16(8-4-2)22(15)32-12-6-5-11-28-19(29)9-10-20(28)30/h13-14H,3-12H2,1-2H3 VYIFDGKVLJBZMT-UHFFFAOYSA-N 50064382 CHEMBL3403688 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064382&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962913 313071274 CHEMBL3403688 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299901 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1CCOC1=O)C(F)(F)F InChI=1S/C23H28F3NO5/c1-3-7-15-13-17-18(23(24,25)26)14-19(28)32-21(17)16(8-4-2)20(15)30-11-6-5-9-27-10-12-31-22(27)29/h13-14H,3-12H2,1-2H3 CLTFJECANIYRTE-UHFFFAOYSA-N 50064383 CHEMBL3403689 Oxysterols receptor LXR-beta 2200 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064383&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118729957 313071275 CHEMBL3403689 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299902 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)C(C)N(C)C1=O)C(F)(F)F InChI=1S/C25H31F3N2O5/c1-5-9-16-13-18-19(25(26,27)28)14-20(31)35-22(18)17(10-6-2)21(16)34-12-8-7-11-30-23(32)15(3)29(4)24(30)33/h13-15H,5-12H2,1-4H3 IGHPSJPFOMUIQM-UHFFFAOYSA-N 50064379 CHEMBL3403691 Oxysterols receptor LXR-beta 1300 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064379&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57963018 313071271 CHEMBL3403691 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299903 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)N(C)C(C)(C)C1=O)C(F)(F)F InChI=1S/C26H33F3N2O5/c1-6-10-16-14-18-19(26(27,28)29)15-20(32)36-22(18)17(11-7-2)21(16)35-13-9-8-12-31-23(33)25(3,4)30(5)24(31)34/h14-15H,6-13H2,1-5H3 UWKFONJSQSWJAL-UHFFFAOYSA-N 50064378 CHEMBL3403692 Oxysterols receptor LXR-beta 4700 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064378&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962956 313071270 CHEMBL3403692 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299904 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)C1=O)C(F)(F)F InChI=1S/C24H29F3N2O5/c1-4-8-15-12-17-18(24(25,26)27)13-19(30)34-21(17)16(9-5-2)20(15)33-11-7-6-10-29-22(31)14(3)28-23(29)32/h12-14H,4-11H2,1-3H3,(H,28,32) HYQWNQWOJIFRRP-UHFFFAOYSA-N 50064377 CHEMBL3403693 Oxysterols receptor LXR-beta 1300 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064377&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962935 313071269 CHEMBL3403693 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299905 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccccc1)C(F)(F)F InChI=1S/C30H33F3N2O5/c1-4-11-19-17-22-23(30(31,32)33)18-24(36)40-26(22)21(12-5-2)25(19)39-16-10-9-15-35-27(37)29(3,34-28(35)38)20-13-7-6-8-14-20/h6-8,13-14,17-18H,4-5,9-12,15-16H2,1-3H3,(H,34,38) AJXCWDWFPSMPLC-UHFFFAOYSA-N 50064384 CHEMBL3403695 Oxysterols receptor LXR-beta 5300 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064384&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962994 313071276 CHEMBL3403695 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299906 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(C)cc1)C(F)(F)F InChI=1S/C31H35F3N2O5/c1-5-9-20-17-23-24(31(32,33)34)18-25(37)41-27(23)22(10-6-2)26(20)40-16-8-7-15-36-28(38)30(4,35-29(36)39)21-13-11-19(3)12-14-21/h11-14,17-18H,5-10,15-16H2,1-4H3,(H,35,39) GUPLTNNIGRFWDD-UHFFFAOYSA-N 50064385 CHEMBL3403696 Oxysterols receptor LXR-beta 2400 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064385&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962869 313071277 CHEMBL3403696 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299907 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC)cc1)C(F)(F)F InChI=1S/C31H35F3N2O6/c1-5-9-19-17-23-24(31(32,33)34)18-25(37)42-27(23)22(10-6-2)26(19)41-16-8-7-15-36-28(38)30(3,35-29(36)39)20-11-13-21(40-4)14-12-20/h11-14,17-18H,5-10,15-16H2,1-4H3,(H,35,39) NKVYSNNVQZTVMZ-UHFFFAOYSA-N 50064386 CHEMBL3403699 Oxysterols receptor LXR-beta 960 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064386&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962891 313071278 CHEMBL3403699 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299908 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc2OCOc2c1)C(F)(F)F InChI=1S/C31H33F3N2O7/c1-4-8-18-14-21-22(31(32,33)34)16-25(37)43-27(21)20(9-5-2)26(18)40-13-7-6-12-36-28(38)30(3,35-29(36)39)19-10-11-23-24(15-19)42-17-41-23/h10-11,14-16H,4-9,12-13,17H2,1-3H3,(H,35,39) PWPAZGUJZWHURL-UHFFFAOYSA-N 50064387 CHEMBL3403701 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064387&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44218087 313071279 CHEMBL3403701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299909 CCCc1cc2c(cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)[N+]([O-])=O)C(F)(F)F InChI=1S/C30H32F3N3O7/c1-4-8-18-16-22-23(30(31,32)33)17-24(37)43-26(22)21(9-5-2)25(18)42-15-7-6-14-35-27(38)29(3,34-28(35)39)19-10-12-20(13-11-19)36(40)41/h10-13,16-17H,4-9,14-15H2,1-3H3,(H,34,39) JJPMMOQSPNZDRD-UHFFFAOYSA-N 50064388 CHEMBL3403704 Oxysterols receptor LXR-beta 8000 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064388&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962776 313071280 CHEMBL3403704 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299910 CCCc1c(OCCCCN2C(=O)CN(C)C2=O)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C21H23F3N2O5/c1-3-6-14-16(30-10-5-4-9-26-17(27)12-25(2)20(26)29)8-7-13-15(21(22,23)24)11-18(28)31-19(13)14/h7-8,11H,3-6,9-10,12H2,1-2H3 HLKCEDIORRRUOI-UHFFFAOYSA-N 50064389 CHEMBL3403707 Oxysterols receptor LXR-beta 1300 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064389&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962965 313071281 CHEMBL3403707 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299911 CCCc1c(OCCCCN2C(=O)N(C)C(C)(C)C2=O)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C23H27F3N2O5/c1-5-8-15-17(10-9-14-16(23(24,25)26)13-18(29)33-19(14)15)32-12-7-6-11-28-20(30)22(2,3)27(4)21(28)31/h9-10,13H,5-8,11-12H2,1-4H3 AIPZKNVPWAZNKM-UHFFFAOYSA-N 50064356 CHEMBL3403708 Oxysterols receptor LXR-beta 1020 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064356&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962786 103959408 CHEMBL3403708 ZINC96237633 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299912 CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccccc2)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C27H27F3N2O5/c1-3-9-19-21(13-12-18-20(27(28,29)30)16-22(33)37-23(18)19)36-15-8-7-14-32-24(34)26(2,31-25(32)35)17-10-5-4-6-11-17/h4-6,10-13,16H,3,7-9,14-15H2,1-2H3,(H,31,35) LOBXHRNVZRMZTO-UHFFFAOYSA-N 50064390 CHEMBL3403709 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064390&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962903 313071282 CHEMBL3403709 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299914 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 410 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50299916 CCCc1c(OCCCN2C(=O)CSC2=O)ccc2c(noc12)C(F)(F)F InChI=1S/C17H17F3N2O4S/c1-2-4-10-12(25-8-3-7-22-13(23)9-27-16(22)24)6-5-11-14(10)26-21-15(11)17(18,19)20/h5-6H,2-4,7-9H2,1H3 YJVYOKPEHRXKEJ-UHFFFAOYSA-N 50064391 CHEMBL3403715 Oxysterols receptor LXR-beta 690 ChEMBL 10.1016/j.bmcl.2015.01.047 10.7270/Q2CC12BH 25677664 Matsuda, T; Okuda, A; Watanabe, Y; Miura, T; Ozawa, H; Tosaka, A; Yamazaki, K; Yamaguchi, Y; Kurobuchi, S; Koura, M; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064391&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9930940 313071283 CHEMBL3403715 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354203 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1cccc(OC)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C25H21N5O3/c1-15(31)27-19-13-18-9-12-30-22(18)20(14-19)21(16-5-3-2-4-6-16)28-23(25(30)33)29-24(32)17-7-10-26-11-8-17/h2-8,10-11,13-14,23H,9,12H2,1H3,(H,27,31)(H,29,32)/t23-/m0/s1 LZXIKYNEHKHNCH-QHCPKHFHSA-N 50094777 CHEMBL3590273 Oxysterols receptor LXR-beta 2200 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094777&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122181445 103992640 CHEMBL3590273 ZINC13835625 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354204 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)C(C)C)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C29H28N8O2/c1-17-14-23-32-33-24(18(2)37(23)34-17)28(38)31-27-29(39)36-13-10-20-15-21(35-11-6-7-12-35)16-22(26(20)36)25(30-27)19-8-4-3-5-9-19/h3-5,8-9,14-16,27H,6-7,10-13H2,1-2H3,(H,31,38)/t27-/m0/s1 SMOBFXSXJCNBMQ-MHZLTWQESA-N 50094778 CHEMBL3588879 Oxysterols receptor LXR-beta 2200 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094778&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24991433 103992641 CHEMBL3588879 ZINC03827882 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354205 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H23N7O3/c1-14-11-20-29-30-21(15(2)33(20)31-14)25(34)28-24-26(35)32-10-9-17-12-18(36-3)13-19(23(17)32)22(27-24)16-7-5-4-6-8-16/h4-8,11-13,24H,9-10H2,1-3H3,(H,28,34)/t24-/m0/s1 SPQIIZKFBVYGPY-DEOSSOPVSA-N 50094779 CHEMBL3588880 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094779&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24991077 103992642 CHEMBL3588880 ZINC13835641 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354207 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccccc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H21Cl2N5O3/c1-13(34)30-17-9-15-7-8-33-23(15)18(12-17)22(14-5-3-2-4-6-14)31-24(26(33)36)32-25(35)16-10-19(27)21(29)20(28)11-16/h2-6,9-12,24H,7-8,29H2,1H3,(H,30,34)(H,32,35)/t24-/m0/s1 DXBKTQMADALMPE-DEOSSOPVSA-N 50094780 CHEMBL3588881 Oxysterols receptor LXR-beta 12000 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094780&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 87123160 103992643 CHEMBL3588881 ZINC27527299 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354266 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354267 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354271 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H20N6O2/c24-15-10-14-7-9-29-20(14)17(11-15)19(13-4-2-1-3-5-13)27-21(23(29)31)28-22(30)16-6-8-26-12-18(16)25/h1-6,8,10-12,21H,7,9,24-25H2,(H,28,30)/t21-/m0/s1 DOEZEEWEYXCSLV-NRFANRHFSA-N 50094781 CHEMBL3589805 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094781&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235143 103992644 CHEMBL3589805 ZINC13835643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354273 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)N(C)C(C)(C)C1=O)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C24H19Cl2N5O2/c25-17-9-14(10-18(26)19(17)28)23(32)30-22-24(33)31-7-6-13-8-15(27)11-16(21(13)31)20(29-22)12-4-2-1-3-5-12/h1-5,8-11,22H,6-7,27-28H2,(H,30,32)/t22-/m0/s1 KGLQCVFPIGHIAB-QFIPXVFZSA-N 50094782 CHEMBL3588882 Oxysterols receptor LXR-beta 560 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094782&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235012 103992645 CHEMBL3588882 ZINC03827873 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354274 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H23Cl2N5O2/c1-32(2)17-10-15-8-9-33-23(15)18(13-17)22(14-6-4-3-5-7-14)30-24(26(33)35)31-25(34)16-11-19(27)21(29)20(28)12-16/h3-7,10-13,24H,8-9,29H2,1-2H3,(H,31,34)/t24-/m0/s1 VWTOPXBUNQDCKW-DEOSSOPVSA-N 50094783 CHEMBL3588883 Oxysterols receptor LXR-beta 1800 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094783&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24986297 103992646 CHEMBL3588883 ZINC03827880 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354275 CCCc1cc(ccc1OCCCCN1C(=O)N(C)C(C)(C)C1=O)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H22N4O3/c1-35-21-14-19-11-12-32-25(19)22(15-21)24(17-7-3-2-4-8-17)30-26(28(32)34)31-27(33)20-13-18-9-5-6-10-23(18)29-16-20/h2-10,13-16,26H,11-12H2,1H3,(H,31,33)/t26-/m0/s1 FWASIVSJUXGFFC-SANMLTNESA-N 50094784 CHEMBL3588884 Oxysterols receptor LXR-beta 1900 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094784&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24991075 103992647 CHEMBL3588884 ZINC13835635 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354277 CCCc1c2COC(c2ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C27H25N5O2/c33-26(19-8-11-28-12-9-19)30-25-27(34)32-15-10-20-16-21(31-13-4-5-14-31)17-22(24(20)32)23(29-25)18-6-2-1-3-7-18/h1-3,6-9,11-12,16-17,25H,4-5,10,13-15H2,(H,30,33)/t25-/m0/s1 QSYHFFMXNLYLGJ-VWLOTQADSA-N 50094785 CHEMBL3588885 Oxysterols receptor LXR-beta 1000 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094785&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57900760 103992648 CHEMBL3588885 ZINC13835624 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354278 CCCc1c2COC(c2ccc1OCCCCN1C(=O)N(C)C(C)(C)C1=O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H17N5O4/c29-22(16-7-4-9-24-13-16)26-21-23(30)27-10-8-15-11-17(28(31)32)12-18(20(15)27)19(25-21)14-5-2-1-3-6-14/h1-7,9,11-13,21H,8,10H2,(H,26,29)/t21-/m0/s1 NIOKUDYXQCLMCD-NRFANRHFSA-N 50094786 CHEMBL3588886 Oxysterols receptor LXR-beta 860 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094786&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57900823 103992649 CHEMBL3588886 ZINC13835627 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354279 CCCc1c(OCCCCN2C(=O)N(C)C(C)(C)C2=O)ccc2C(CCOc12)C(F)(F)F InChI=1S/C23H31F3N2O4/c1-5-8-16-18(10-9-15-17(23(24,25)26)11-14-32-19(15)16)31-13-7-6-12-28-20(29)22(2,3)27(4)21(28)30/h9-10,17H,5-8,11-14H2,1-4H3 WQAUTIGHUZYURS-UHFFFAOYSA-N 50094870 CHEMBL3588887 Oxysterols receptor LXR-beta 2000 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094870&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122180565 318473511 CHEMBL3588887 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354281 CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccc(OC)cc2)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C28H29F3N2O6/c1-4-7-20-22(13-12-19-21(28(29,30)31)16-23(34)39-24(19)20)38-15-6-5-14-33-25(35)27(2,32-26(33)36)17-8-10-18(37-3)11-9-17/h8-13,16H,4-7,14-15H2,1-3H3,(H,32,36) ABUHBGNGKQNACH-UHFFFAOYSA-N 50064330 CHEMBL3403710 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064330&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44217616 313071266 CHEMBL3403710 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354282 CCCc1c(OCCCCN2C(=O)N(C)C(C)(C)C2=O)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C23H27F3N2O5/c1-5-8-15-17(10-9-14-16(23(24,25)26)13-18(29)33-19(14)15)32-12-7-6-11-28-20(30)22(2,3)27(4)21(28)31/h9-10,13H,5-8,11-12H2,1-4H3 AIPZKNVPWAZNKM-UHFFFAOYSA-N 50064356 CHEMBL3403708 Oxysterols receptor LXR-beta 1000 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064356&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57962786 103959408 CHEMBL3403708 ZINC96237633 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354283 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(CC)(C1=O)c1ccc2OCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C27H21N5O2/c28-20-13-18-10-11-32-24(18)21(14-20)23(16-6-2-1-3-7-16)30-25(27(32)34)31-26(33)19-12-17-8-4-5-9-22(17)29-15-19/h1-9,12-15,25H,10-11,28H2,(H,31,33)/t25-/m0/s1 ZHOCQFVWAAJXSH-VWLOTQADSA-N 50094787 CHEMBL3588892 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094787&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234921 103992650 CHEMBL3588892 ZINC03827878 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354284 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(CC)(C1=O)c1ccc(OC)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H27N5O4/c1-28(2,3)37-27(36)30-21-16-29-14-12-19(21)25(34)32-24-26(35)33-15-13-18-10-7-11-20(23(18)33)22(31-24)17-8-5-4-6-9-17/h4-12,14,16,24H,13,15H2,1-3H3,(H,30,36)(H,32,34)/t24-/m0/s1 XIEGMFUYEDDKDL-DEOSSOPVSA-N 50094788 CHEMBL3588891 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094788&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235084 103992651 CHEMBL3588891 ZINC13835631 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354285 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)-c1ccccc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H17Cl2N5O2/c24-16-10-27-11-17(25)18(16)22(31)29-21-23(32)30-7-6-13-8-14(26)9-15(20(13)30)19(28-21)12-4-2-1-3-5-12/h1-5,8-11,21H,6-7,26H2,(H,29,31)/t21-/m0/s1 ARYMSOFDUIIUNT-NRFANRHFSA-N 50094789 CHEMBL3588890 Oxysterols receptor LXR-beta 1600 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094789&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235136 103992652 CHEMBL3588890 ZINC13835630 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354286 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)C(C)C)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C24H21N5O2/c25-17-8-6-15(7-9-17)23(30)28-22-24(31)29-11-10-16-12-18(26)13-19(21(16)29)20(27-22)14-4-2-1-3-5-14/h1-9,12-13,22H,10-11,25-26H2,(H,28,30)/t22-/m0/s1 FMFKDGNEGFCHBU-QFIPXVFZSA-N 50094790 CHEMBL3588889 Oxysterols receptor LXR-beta 1700 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094790&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234887 103992653 CHEMBL3588889 ZINC13835644 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354287 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc2OCCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13?,16-/m1/s1 SVFXPTLYMIXFRX-FQNRMIAFSA-N 50094797 CHEMBL3588888 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094797&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234958 103992660 CHEMBL3588888 ZINC03872906 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354288 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc2OCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C30H34F6N2O6/c1-4-8-18-14-21(28(41,29(31,32)33)30(34,35)36)15-19(9-5-2)24(18)42-13-7-6-12-38-25(39)27(3,37-26(38)40)20-10-11-22-23(16-20)44-17-43-22/h10-11,14-16,41H,4-9,12-13,17H2,1-3H3,(H,37,40) VWGTWONEZRKZRQ-UHFFFAOYSA-N 50094849 CHEMBL3589801 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094849&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235130 103992712 CHEMBL3589801 ZINC13835710 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354289 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC(F)(F)F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C30H33F9N2O5/c1-4-8-18-16-21(27(44,28(31,32)33)29(34,35)36)17-19(9-5-2)23(18)45-15-7-6-14-41-24(42)26(3,40-25(41)43)20-10-12-22(13-11-20)46-30(37,38)39/h10-13,16-17,44H,4-9,14-15H2,1-3H3,(H,40,43) SGCDSLHTYKBRQO-UHFFFAOYSA-N 50094850 CHEMBL3589802 Oxysterols receptor LXR-beta 2700 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094850&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234999 103992713 CHEMBL3589802 ZINC13835695 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354290 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H40F6N2O5/c1-6-10-21-18-24(30(43,31(33,34)35)32(36,37)38)19-22(11-7-2)26(21)44-17-9-8-16-40-27(41)29(5,39-28(40)42)23-12-14-25(15-13-23)45-20(3)4/h12-15,18-20,43H,6-11,16-17H2,1-5H3,(H,39,42) DFZLKVIVVZKYKP-UHFFFAOYSA-N 50094851 CHEMBL3589803 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094851&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 56589730 103992714 CHEMBL3589803 ZINC13835708 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354291 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OCC)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C31H38F6N2O5/c1-5-10-20-18-23(29(42,30(32,33)34)31(35,36)37)19-21(11-6-2)25(20)44-17-9-8-16-39-26(40)28(4,38-27(39)41)22-12-14-24(15-13-22)43-7-3/h12-15,18-19,42H,5-11,16-17H2,1-4H3,(H,38,41) IAUYPBWLYMUNHS-UHFFFAOYSA-N 50094852 CHEMBL3589804 Oxysterols receptor LXR-beta 800 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094852&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235082 103992715 CHEMBL3589804 ZINC13835712 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354292 CCCc1cc(ccc1OCCCCN1C(=O)NC(CC)(C1=O)c1ccc2OCCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C29H32F6N2O6/c1-3-7-18-16-20(27(40,28(30,31)32)29(33,34)35)9-10-21(18)41-13-6-5-12-37-24(38)26(4-2,36-25(37)39)19-8-11-22-23(17-19)43-15-14-42-22/h8-11,16-17,40H,3-7,12-15H2,1-2H3,(H,36,39) ZVBBQBPDJQNSCO-UHFFFAOYSA-N 50094853 CHEMBL3589806 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094853&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235170 103992716 CHEMBL3589806 ZINC13835699 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354314 CCCc1cc(ccc1OCCCCN1C(=O)NC(CCC)(C1=O)c1ccc2OCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C29H32F6N2O6/c1-3-7-18-15-20(27(40,28(30,31)32)29(33,34)35)9-10-21(18)41-14-6-5-13-37-24(38)26(12-4-2,36-25(37)39)19-8-11-22-23(16-19)43-17-42-22/h8-11,15-16,40H,3-7,12-14,17H2,1-2H3,(H,36,39) GQOLSCVKNZBZPG-UHFFFAOYSA-N 50094854 CHEMBL3590258 Oxysterols receptor LXR-beta 1300 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094854&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235049 103992717 CHEMBL3590258 ZINC13835691 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354315 CCCc1cc(ccc1OCCCCN1C(=O)NC(CC)(C1=O)c1ccc2OCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H30F6N2O6/c1-3-7-17-14-19(26(39,27(29,30)31)28(32,33)34)9-10-20(17)40-13-6-5-12-36-23(37)25(4-2,35-24(36)38)18-8-11-21-22(15-18)42-16-41-21/h8-11,14-15,39H,3-7,12-13,16H2,1-2H3,(H,35,38) ANGMNRLPRMARHS-UHFFFAOYSA-N 50094855 CHEMBL3590259 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094855&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235054 103992718 CHEMBL3590259 ZINC13835697 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354316 CCCc1cc(ccc1OCCCCN1C(=O)NC(CC)(C1=O)c1ccc(OC)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H32F6N2O5/c1-4-8-18-17-20(26(39,27(29,30)31)28(32,33)34)11-14-22(18)41-16-7-6-15-36-23(37)25(5-2,35-24(36)38)19-9-12-21(40-3)13-10-19/h9-14,17,39H,4-8,15-16H2,1-3H3,(H,35,38) ZUSRAIJOSOQEQJ-UHFFFAOYSA-N 50094856 CHEMBL3590260 Oxysterols receptor LXR-beta 1000 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094856&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234955 103992719 CHEMBL3590260 ZINC13835707 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354317 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)[N+]([O-])=O)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C11H11N3O6/c1-2-19-10-4(9(11(17)18)20-14-10)3-13-6-5(12)7(15)8(6)16/h12,15-16H,2-3H2,1H3,(H,17,18)/b12-5?,13-6- SSVHFTXSEPSMBZ-WNCIRQTPSA-N 50094857 CHEMBL3590261 Oxysterols receptor LXR-beta 1900 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094857&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24991787 103992720 CHEMBL3590261 ZINC03823012 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354318 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)C(F)(F)F)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C27H27F9N2O4/c1-3-6-16-15-19(24(41,26(31,32)33)27(34,35)36)11-12-20(16)42-14-5-4-13-38-21(39)23(2,37-22(38)40)17-7-9-18(10-8-17)25(28,29)30/h7-12,15,41H,3-6,13-14H2,1-2H3,(H,37,40) JAPREEGNPQOVJF-UHFFFAOYSA-N 50094858 CHEMBL3590262 Oxysterols receptor LXR-beta 1800 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094858&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24991785 103992721 CHEMBL3590262 ZINC13835701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354319 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)-c1ccccc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H32F6N2O4/c1-3-9-23-20-25(30(43,31(33,34)35)32(36,37)38)16-17-26(23)44-19-8-7-18-40-27(41)29(2,39-28(40)42)24-14-12-22(13-15-24)21-10-5-4-6-11-21/h4-6,10-17,20,43H,3,7-9,18-19H2,1-2H3,(H,39,42) UEWFCKBEUKEKMB-UHFFFAOYSA-N 50094859 CHEMBL3590263 Oxysterols receptor LXR-beta 1000 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094859&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235110 103992722 CHEMBL3590263 ZINC13835705 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354320 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(Cl)c(Cl)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H26Cl2F6N2O4/c1-3-6-15-13-17(24(39,25(29,30)31)26(32,33)34)8-10-20(15)40-12-5-4-11-36-21(37)23(2,35-22(36)38)16-7-9-18(27)19(28)14-16/h7-10,13-14,39H,3-6,11-12H2,1-2H3,(H,35,38) PRQDVCHEULTZPU-UHFFFAOYSA-N 50094860 CHEMBL3590264 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094860&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234998 103992723 CHEMBL3590264 ZINC13835703 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354321 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(Cl)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C26H27ClF6N2O4/c1-3-6-16-15-18(24(38,25(28,29)30)26(31,32)33)9-12-20(16)39-14-5-4-13-35-21(36)23(2,34-22(35)37)17-7-10-19(27)11-8-17/h7-12,15,38H,3-6,13-14H2,1-2H3,(H,34,37) IVZHAMUPJCMLIY-UHFFFAOYSA-N 50094861 CHEMBL3590265 Oxysterols receptor LXR-beta 1800 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094861&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24991436 103992724 CHEMBL3590265 ZINC13835693 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354322 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(cc1)N(C)C)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H33F6N3O4/c1-5-8-18-17-20(26(40,27(29,30)31)28(32,33)34)11-14-22(18)41-16-7-6-15-37-23(38)25(2,35-24(37)39)19-9-12-21(13-10-19)36(3)4/h9-14,17,40H,5-8,15-16H2,1-4H3,(H,35,39) RFWGIZMRALGUEU-UHFFFAOYSA-N 50094862 CHEMBL3590266 Oxysterols receptor LXR-beta 2700 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094862&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24991788 103992725 CHEMBL3590266 ZINC01488496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354323 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc2OCCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C28H30F6N2O6/c1-3-6-17-15-19(26(39,27(29,30)31)28(32,33)34)8-9-20(17)40-12-5-4-11-36-23(37)25(2,35-24(36)38)18-7-10-21-22(16-18)42-14-13-41-21/h7-10,15-16,39H,3-6,11-14H2,1-2H3,(H,35,38) UIZSEGRNMFTFEN-UHFFFAOYSA-N 50094863 CHEMBL3590267 Oxysterols receptor LXR-beta 400 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094863&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59235080 103992726 CHEMBL3590267 ZINC13835689 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354324 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc2OCOc2c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C27H28F6N2O6/c1-3-6-16-13-18(25(38,26(28,29)30)27(31,32)33)8-9-19(16)39-12-5-4-11-35-22(36)24(2,34-23(35)37)17-7-10-20-21(14-17)41-15-40-20/h7-10,13-14,38H,3-6,11-12,15H2,1-2H3,(H,34,37) RKVUYLWNCWZIKP-UHFFFAOYSA-N 50094864 CHEMBL3590268 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094864&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24808559 103992727 CHEMBL3590268 ZINC13835687 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354325 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC(F)(F)F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C34H47N5O6/c1-5-21(3)28-34(45)39-19-13-12-18-27(39)32(43)35-25(16-9-7-8-14-22(40)6-2)31(42)37-29(33(44)36-28)24-20-38(4)26-17-11-10-15-23(26)30(24)41/h10-11,15,17,20-21,25,27-29H,5-9,12-14,16,18-19H2,1-4H3,(H,35,43)(H,36,44)(H,37,42)/t21?,25-,27+,28-,29-/m0/s1 MBUPURNAOZZFIU-RYADJZTKSA-N 50094865 CHEMBL3590269 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094865&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234874 103992728 CHEMBL3590269 ZINC27553189 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354326 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C34H47N5O7/c1-5-21(3)28-34(45)38-19-13-12-18-27(38)32(43)35-25(16-9-7-8-14-22(40)6-2)31(42)37-29(33(44)36-28)24-20-39(46-4)26-17-11-10-15-23(26)30(24)41/h10-11,15,17,20-21,25,27-29H,5-9,12-14,16,18-19H2,1-4H3,(H,35,43)(H,36,44)(H,37,42)/t21?,25-,27+,28-,29-/m0/s1 IEVZGTIIJVLPRE-RYADJZTKSA-N 50094866 CHEMBL3590270 Oxysterols receptor LXR-beta 2800 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094866&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24986301 103992729 CHEMBL3590270 ZINC36338659 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354327 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OCC)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C35H49N5O6/c1-5-22(4)29-35(46)40-20-14-13-19-28(40)33(44)36-26(17-10-8-9-15-23(41)6-2)32(43)38-30(34(45)37-29)25-21-39(7-3)27-18-12-11-16-24(27)31(25)42/h11-12,16,18,21-22,26,28-30H,5-10,13-15,17,19-20H2,1-4H3,(H,36,44)(H,37,45)(H,38,43)/t22?,26-,28+,29-,30-/m0/s1 QIRFIQOIPIMCJZ-WEABMUKJSA-N 50094867 CHEMBL3590271 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094867&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24986299 103992730 CHEMBL3590271 ZINC36338663 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50354328 CCCc1cc(ccc1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC)c(OC)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C36H51N5O6/c1-5-20-40-22-26(32(43)25-16-11-12-18-28(25)40)31-35(46)38-30(23(4)6-2)36(47)41-21-14-13-19-29(41)34(45)37-27(33(44)39-31)17-10-8-9-15-24(42)7-3/h11-12,16,18,22-23,27,29-31H,5-10,13-15,17,19-21H2,1-4H3,(H,37,45)(H,38,46)(H,39,44)/t23?,27-,29+,30-,31-/m0/s1 QCAGJJVUDIGMDW-CRUOVYIHSA-N 50094868 CHEMBL3590272 Oxysterols receptor LXR-beta 1300 ChEMBL 10.1016/j.bmcl.2015.04.080 10.7270/Q2PN97CM 25998501 Koura, M; Matsuda, T; Okuda, A; Watanabe, Y; Yamaguchi, Y; Kurobuchi, S; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094868&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234952 103992731 CHEMBL3590272 ZINC27554583 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50382641 OC(=O)c1ccc(cc1)-c1nc(C(=O)c2c(Cl)cccc2C(F)(F)F)n2ccccc12 InChI=1S/C22H12ClF3N2O3/c23-15-5-3-4-14(22(24,25)26)17(15)19(29)20-27-18(16-6-1-2-11-28(16)20)12-7-9-13(10-8-12)21(30)31/h1-11H,(H,30,31) RUEKRLSPXAQNCP-UHFFFAOYSA-N 50106286 CHEMBL3598141::US9550771, Example 27 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2015.05.055 10.7270/Q2HT2R3R 26048793 Fauber, BP; Gobbi, A; Robarge, K; Zhou, A; Barnard, A; Cao, J; Deng, Y; Eidenschenk, C; Everett, C; Ganguli, A; Hawkins, J; Johnson, AR; La, H; Norman, M; Salmon, G; Summerhill, S; Ouyang, W; Tang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106286&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117964978 319492790 CHEMBL3598141 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50382642 OC(=O)c1ccc(cc1O)-c1nc(C(=O)c2c(Cl)cccc2C(F)(F)F)n2ccccc12 InChI=1S/C22H12ClF3N2O4/c23-14-5-3-4-13(22(24,25)26)17(14)19(30)20-27-18(15-6-1-2-9-28(15)20)11-7-8-12(21(31)32)16(29)10-11/h1-10,29H,(H,31,32) UAAUZNSONHHQQI-UHFFFAOYSA-N 50106287 CHEMBL3598148::US9550771, Example 17 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2015.05.055 10.7270/Q2HT2R3R 26048793 Fauber, BP; Gobbi, A; Robarge, K; Zhou, A; Barnard, A; Cao, J; Deng, Y; Eidenschenk, C; Everett, C; Ganguli, A; Hawkins, J; Johnson, AR; La, H; Norman, M; Salmon, G; Summerhill, S; Ouyang, W; Tang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106287&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91664317 319492791 CHEMBL3598148 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50382643 OC(=O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C(F)(F)F)n3ccccc23)c(F)c1 InChI=1S/C22H11ClF4N2O3/c23-14-5-3-4-13(22(25,26)27)17(14)19(30)20-28-18(16-6-1-2-9-29(16)20)12-8-7-11(21(31)32)10-15(12)24/h1-10H,(H,31,32) LTTBADSZQZHNMO-UHFFFAOYSA-N 50106288 CHEMBL3598149::US9550771, Example 28 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2015.05.055 10.7270/Q2HT2R3R 26048793 Fauber, BP; Gobbi, A; Robarge, K; Zhou, A; Barnard, A; Cao, J; Deng, Y; Eidenschenk, C; Everett, C; Ganguli, A; Hawkins, J; Johnson, AR; La, H; Norman, M; Salmon, G; Summerhill, S; Ouyang, W; Tang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117964962 319492792 CHEMBL3598149 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50382644 OC(=O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C(F)(F)F)n3CCCCc23)c(F)c1 InChI=1S/C22H15ClF4N2O3/c23-14-5-3-4-13(22(25,26)27)17(14)19(30)20-28-18(16-6-1-2-9-29(16)20)12-8-7-11(21(31)32)10-15(12)24/h3-5,7-8,10H,1-2,6,9H2,(H,31,32) BQKPQRMICRYEPE-UHFFFAOYSA-N 50106289 CHEMBL3596270::US9550771, Example 21 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2015.05.055 10.7270/Q2HT2R3R 26048793 Fauber, BP; Gobbi, A; Robarge, K; Zhou, A; Barnard, A; Cao, J; Deng, Y; Eidenschenk, C; Everett, C; Ganguli, A; Hawkins, J; Johnson, AR; La, H; Norman, M; Salmon, G; Summerhill, S; Ouyang, W; Tang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106289&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117964998 319492793 CHEMBL3596270 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50382645 OC(=O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C3CC3)n3CCCCc23)c(F)c1 InChI=1S/C24H20ClFN2O3/c25-17-5-3-4-15(13-7-8-13)20(17)22(29)23-27-21(19-6-1-2-11-28(19)23)16-10-9-14(24(30)31)12-18(16)26/h3-5,9-10,12-13H,1-2,6-8,11H2,(H,30,31) PCWVUKNALKMATE-UHFFFAOYSA-N 50106290 CHEMBL3596276::US9550771, Example 89 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2015.05.055 10.7270/Q2HT2R3R 26048793 Fauber, BP; Gobbi, A; Robarge, K; Zhou, A; Barnard, A; Cao, J; Deng, Y; Eidenschenk, C; Everett, C; Ganguli, A; Hawkins, J; Johnson, AR; La, H; Norman, M; Salmon, G; Summerhill, S; Ouyang, W; Tang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106290&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117964973 319492794 CHEMBL3596276 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50382646 OC(=O)c1ccc(cc1O)-c1nc(C(=O)c2c(Cl)cccc2C2CC2)n2cccnc12 InChI=1S/C23H16ClN3O4/c24-16-4-1-3-14(12-5-6-12)18(16)20(29)22-26-19(21-25-9-2-10-27(21)22)13-7-8-15(23(30)31)17(28)11-13/h1-4,7-12,28H,5-6H2,(H,30,31) GIYKJPISDNWSJD-UHFFFAOYSA-N 50106285 CHEMBL3596279::US9550771, Example 91 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2015.05.055 10.7270/Q2HT2R3R 26048793 Fauber, BP; Gobbi, A; Robarge, K; Zhou, A; Barnard, A; Cao, J; Deng, Y; Eidenschenk, C; Everett, C; Ganguli, A; Hawkins, J; Johnson, AR; La, H; Norman, M; Salmon, G; Summerhill, S; Ouyang, W; Tang, W; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106285&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117964975 319492789 CHEMBL3596279 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50401762 CC(C)(C)OC(=O)c1c(O)c(ccc1COc1ccc(cc1)-c1ccc(CC(O)=O)cc1)C(F)(F)F InChI=1S/C27H25F3O6/c1-26(2,3)36-25(34)23-19(10-13-21(24(23)33)27(28,29)30)15-35-20-11-8-18(9-12-20)17-6-4-16(5-7-17)14-22(31)32/h4-13,33H,14-15H2,1-3H3,(H,31,32) XWHRMVBUKJEZFY-UHFFFAOYSA-N 50115191 CHEMBL3609573 Oxysterols receptor LXR-beta 160 ChEMBL 10.1016/j.bmcl.2015.07.047 10.7270/Q23T9K08 26238323 Matsui, Y; Yamaguchi, T; Yamazaki, T; Yoshida, M; Arai, M; Terasaka, N; Honzumi, S; Wakabayashi, K; Hayashi, S; Nakai, D; Hanzawa, H; Tamaki, K Daiichi Sankyo RD Novare Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115191&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4KQ 5AVL 11555148 104009168 CHEMBL3609573 C03768 ZINC13474647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50401763 CC(C)(C)OC(=O)c1c(O)c(ccc1COc1ccc(cc1)-c1cccc(CC(O)=O)c1)C(F)(F)F InChI=1S/C27H25F3O6/c1-26(2,3)36-25(34)23-19(9-12-21(24(23)33)27(28,29)30)15-35-20-10-7-17(8-11-20)18-6-4-5-16(13-18)14-22(31)32/h4-13,33H,14-15H2,1-3H3,(H,31,32) UNORXFZZRFAMMK-UHFFFAOYSA-N 50115192 CHEMBL3609572 Oxysterols receptor LXR-beta 530 ChEMBL 10.1016/j.bmcl.2015.07.047 10.7270/Q23T9K08 26238323 Matsui, Y; Yamaguchi, T; Yamazaki, T; Yoshida, M; Arai, M; Terasaka, N; Honzumi, S; Wakabayashi, K; Hayashi, S; Nakai, D; Hanzawa, H; Tamaki, K Daiichi Sankyo RD Novare Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115192&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 67119337 104009169 CHEMBL3609572 ZINC13474643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50401764 CN(C(C)=O)c1ccc(OCc2ccc(c(O)c2C(=O)OC(C)(C)C)C(F)(F)F)cc1 InChI=1S/C22H24F3NO5/c1-13(27)26(5)15-7-9-16(10-8-15)30-12-14-6-11-17(22(23,24)25)19(28)18(14)20(29)31-21(2,3)4/h6-11,28H,12H2,1-5H3 XRYDEEKHRNPJOZ-UHFFFAOYSA-N 50115193 CHEMBL3609363 Oxysterols receptor LXR-beta 260 ChEMBL 10.1016/j.bmcl.2015.07.047 10.7270/Q23T9K08 26238323 Matsui, Y; Yamaguchi, T; Yamazaki, T; Yoshida, M; Arai, M; Terasaka, N; Honzumi, S; Wakabayashi, K; Hayashi, S; Nakai, D; Hanzawa, H; Tamaki, K Daiichi Sankyo RD Novare Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115193&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11662127 104009170 CHEMBL3609363 ZINC13474634 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50401765 CN(C(C)=O)c1ccc(OCc2ccc(cc2C(=O)OC(C)(C)C)C(F)(F)F)cc1 InChI=1S/C22H24F3NO4/c1-14(27)26(5)17-8-10-18(11-9-17)29-13-15-6-7-16(22(23,24)25)12-19(15)20(28)30-21(2,3)4/h6-12H,13H2,1-5H3 YZWZMPWHXSZLBQ-UHFFFAOYSA-N 50115194 CHEMBL3609362 Oxysterols receptor LXR-beta 210 ChEMBL 10.1016/j.bmcl.2015.07.047 10.7270/Q23T9K08 26238323 Matsui, Y; Yamaguchi, T; Yamazaki, T; Yoshida, M; Arai, M; Terasaka, N; Honzumi, S; Wakabayashi, K; Hayashi, S; Nakai, D; Hanzawa, H; Tamaki, K Daiichi Sankyo RD Novare Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115194&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4KM 5AVI 91827511 104009171 CHEMBL3609362 ZINC13474628 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50401766 OC(=O)c1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C32H29ClF3NO3/c33-30-26(15-8-17-29(30)32(34,35)36)21-37(18-9-19-40-27-16-7-14-25(20-27)31(38)39)22-28(23-10-3-1-4-11-23)24-12-5-2-6-13-24/h1-8,10-17,20,28H,9,18-19,21-22H2,(H,38,39) LYILZTQKEIMJDW-UHFFFAOYSA-N 50115195 CHEMBL3609361 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.bmcl.2015.07.047 10.7270/Q23T9K08 26238323 Matsui, Y; Yamaguchi, T; Yamazaki, T; Yoshida, M; Arai, M; Terasaka, N; Honzumi, S; Wakabayashi, K; Hayashi, S; Nakai, D; Hanzawa, H; Tamaki, K Daiichi Sankyo RD Novare Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115195&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 57757122 104009172 CHEMBL3609361 ZINC13474633 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50401767 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 130 ChEMBL 10.1016/j.bmcl.2015.07.047 10.7270/Q23T9K08 26238323 Matsui, Y; Yamaguchi, T; Yamazaki, T; Yoshida, M; Arai, M; Terasaka, N; Honzumi, S; Wakabayashi, K; Hayashi, S; Nakai, D; Hanzawa, H; Tamaki, K Daiichi Sankyo RD Novare Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417941 O=C1N(C(=O)c2ccccc12)c1ccccc1CCc1ccccc1 InChI=1S/C22H17NO2/c24-21-18-11-5-6-12-19(18)22(25)23(21)20-13-7-4-10-17(20)15-14-16-8-2-1-3-9-16/h1-13H,14-15H2 XGSWAPNRKGOSKD-UHFFFAOYSA-N 23840 2-[2-(2-phenylethyl)phenyl]-2,3-dihydro-1H-isoindole-1,3-dione::CHEMBL246144::PP2P Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23840&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10616182 50092092 CHEMBL246144 ZINC28898291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417942 O=C1N(C(=O)c2ccccc12)c1cccc(CCc2ccccc2)c1 InChI=1S/C22H17NO2/c24-21-19-11-4-5-12-20(19)22(25)23(21)18-10-6-9-17(15-18)14-13-16-7-2-1-3-8-16/h1-12,15H,13-14H2 DJMIPAXALMXBNX-UHFFFAOYSA-N 50298702 CHEMBL575661::N-[3-(2-Phenylethyl)phenyl]phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481853 104140231 CHEMBL575661 ZINC45299971 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417943 O=C1N(C(=O)c2ccccc12)c1ccc(CCc2ccccc2)cc1 InChI=1S/C22H17NO2/c24-21-19-8-4-5-9-20(19)22(25)23(21)18-14-12-17(13-15-18)11-10-16-6-2-1-3-7-16/h1-9,12-15H,10-11H2 AXTFYGWMYSVZKF-UHFFFAOYSA-N 50298704 CHEMBL585552::N-(4-(2-Phenylethyl)phenyl)phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298704&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481819 104140233 CHEMBL585552 ZINC45322531 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417944 O=C1N(C(=O)c2ccccc12)c1ccccc1\C=C\c1ccccc1 InChI=1S/C22H15NO2/c24-21-18-11-5-6-12-19(18)22(25)23(21)20-13-7-4-10-17(20)15-14-16-8-2-1-3-9-16/h1-15H/b15-14+ UPGQKPUMMXGPPZ-CCEZHUSRSA-N 50122627 CHEMBL3623096 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122627&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127293 87350468 CHEMBL3623096 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417951 COc1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C23H17NO3/c1-27-18-14-11-16(12-15-18)10-13-17-6-2-5-9-21(17)24-22(25)19-7-3-4-8-20(19)23(24)26/h2-15H,1H3/b13-10+ AUHXYLYVZAVYRT-JLHYYAGUSA-N 50122628 CHEMBL3623097 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122628&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10221060 85309741 CHEMBL3623097 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417952 Fc1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C22H14FNO2/c23-17-13-10-15(11-14-17)9-12-16-5-1-4-8-20(16)24-21(25)18-6-2-3-7-19(18)22(24)26/h1-14H/b12-9+ CQGZVUSKUJQFCT-FMIVXFBMSA-N 50122629 CHEMBL3623098 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122629&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3246941 87350469 CHEMBL3623098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417953 Brc1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C22H14BrNO2/c23-17-13-10-15(11-14-17)9-12-16-5-1-4-8-20(16)24-21(25)18-6-2-3-7-19(18)22(24)26/h1-14H/b12-9+ JRIROLXARZMUPK-FMIVXFBMSA-N 50122630 CHEMBL3623099 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122630&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11001835 85309755 CHEMBL3623099 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417954 O=C1N(C(=O)c2ccccc12)c1ccccc1\C=C\c1ccc(cc1)C#N InChI=1S/C23H14N2O2/c24-15-17-11-9-16(10-12-17)13-14-18-5-1-4-8-21(18)25-22(26)19-6-2-3-7-20(19)23(25)27/h1-14H/b14-13+ QRRHIDZEDDNRNY-BUHFOSPRSA-N 50122631 CHEMBL3623100 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122631&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9883786 85309768 CHEMBL3623100 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417955 Cc1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C23H17NO2/c1-16-10-12-17(13-11-16)14-15-18-6-2-5-9-21(18)24-22(25)19-7-3-4-8-20(19)23(24)26/h2-15H,1H3/b15-14+ WYNWRSWIWXNKLX-CCEZHUSRSA-N 50122632 CHEMBL3623101 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122632&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11809108 85309832 CHEMBL3623101 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417956 FC(F)(F)c1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C23H14F3NO2/c24-23(25,26)17-13-10-15(11-14-17)9-12-16-5-1-4-8-20(16)27-21(28)18-6-2-3-7-19(18)22(27)29/h1-14H/b12-9+ YKLWNVLPRNRCEK-FMIVXFBMSA-N 50122633 CHEMBL3623102 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122633&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11141402 85309931 CHEMBL3623102 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417957 CCCCc1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C26H23NO2/c1-2-3-8-19-13-15-20(16-14-19)17-18-21-9-4-7-12-24(21)27-25(28)22-10-5-6-11-23(22)26(27)29/h4-7,9-18H,2-3,8H2,1H3/b18-17+ GOEYNEMNRYCTJE-ISLYRVAYSA-N 50122612 CHEMBL3623103 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122612&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122192269 374883900 CHEMBL3623103 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417958 CC(C)(C)c1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C26H23NO2/c1-26(2,3)20-16-13-18(14-17-20)12-15-19-8-4-7-11-23(19)27-24(28)21-9-5-6-10-22(21)25(27)29/h4-17H,1-3H3/b15-12+ LQRNEZAKFFQFIO-NTCAYCPXSA-N 50122616 CHEMBL3623104 Oxysterols receptor LXR-beta 6800 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122616&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10644664 104015278 CHEMBL3623104 ZINC28013100 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417959 COc1ccccc1\C=C\c1ccccc1N1C(=O)c2ccccc2C1=O InChI=1S/C23H17NO3/c1-27-21-13-7-3-9-17(21)15-14-16-8-2-6-12-20(16)24-22(25)18-10-4-5-11-19(18)23(24)26/h2-15H,1H3/b15-14+ XMZFRUMCKXAUSH-CCEZHUSRSA-N 50122617 CHEMBL3623105 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122617&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10549857 104015279 CHEMBL3623105 ZINC28015366 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417960 COc1cccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)c1 InChI=1S/C23H17NO3/c1-27-18-9-6-7-16(15-18)13-14-17-8-2-5-12-21(17)24-22(25)19-10-3-4-11-20(19)23(24)26/h2-15H,1H3/b14-13+ PNEXAUQACLLQLX-BUHFOSPRSA-N 50122618 CHEMBL3623106 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122618&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10906863 104015280 CHEMBL3623106 ZINC28014400 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417961 COc1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H19NO4/c1-28-21-14-12-16(15-22(21)29-2)11-13-17-7-3-6-10-20(17)25-23(26)18-8-4-5-9-19(18)24(25)27/h3-15H,1-2H3/b13-11+ MKFOSSOUEAENMG-ACCUITESSA-N 50122619 CHEMBL3623107 Oxysterols receptor LXR-beta 4300 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122619&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11080769 104015281 CHEMBL3623107 ZINC28091859 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417962 COc1cc(OC)cc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)c1 InChI=1S/C24H19NO4/c1-28-18-13-16(14-19(15-18)29-2)11-12-17-7-3-6-10-22(17)25-23(26)20-8-4-5-9-21(20)24(25)27/h3-15H,1-2H3/b12-11+ QHSIDZPXNJZMQT-VAWYXSNFSA-N 50122620 CHEMBL3623108 Oxysterols receptor LXR-beta 15000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122620&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10623870 104015282 CHEMBL3623108 ZINC28086044 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417963 COc1cc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc(OC)c1OC InChI=1S/C25H21NO5/c1-29-21-14-16(15-22(30-2)23(21)31-3)12-13-17-8-4-7-11-20(17)26-24(27)18-9-5-6-10-19(18)25(26)28/h4-15H,1-3H3/b13-12+ NOCOUTQKQYXYKX-OUKQBFOZSA-N 50122621 CHEMBL3623109 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122621&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10873953 104015283 CHEMBL3623109 ZINC28020217 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417964 COc1ccc(\C=C/c2ccccc2N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H19NO4/c1-28-21-14-12-16(15-22(21)29-2)11-13-17-7-3-6-10-20(17)25-23(26)18-8-4-5-9-19(18)24(25)27/h3-15H,1-2H3/b13-11- MKFOSSOUEAENMG-QBFSEMIESA-N 50122622 CHEMBL3623110 Oxysterols receptor LXR-beta 21000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122622&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10346480 104015284 CHEMBL3623110 ZINC28022530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417965 COc1ccc(CCc2ccccc2N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H21NO4/c1-28-21-14-12-16(15-22(21)29-2)11-13-17-7-3-6-10-20(17)25-23(26)18-8-4-5-9-19(18)24(25)27/h3-10,12,14-15H,11,13H2,1-2H3 GPIKIQYFADSPRZ-UHFFFAOYSA-N 50298700 CHEMBL574787::N-{2-[2-(3,4-Dimethoxyphenyl)ethyl]phenyl}phthalimide Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298700&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481848 104140229 CHEMBL574787 ZINC45288016 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417966 Cc1ccccc1\C=C\c1ccccc1N1C(=O)c2ccccc2C1=O InChI=1S/C23H17NO2/c1-16-8-2-3-9-17(16)14-15-18-10-4-7-13-21(18)24-22(25)19-11-5-6-12-20(19)23(24)26/h2-15H,1H3/b15-14+ UEONABXRMRCAQU-CCEZHUSRSA-N 50122623 CHEMBL3623111 Oxysterols receptor LXR-beta 25000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122623&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10766682 104015285 CHEMBL3623111 ZINC28011511 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417967 Cc1cccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)c1 InChI=1S/C23H17NO2/c1-16-7-6-8-17(15-16)13-14-18-9-2-5-12-21(18)24-22(25)19-10-3-4-11-20(19)23(24)26/h2-15H,1H3/b14-13+ GDGWEZWODLCDBL-BUHFOSPRSA-N 50122624 CHEMBL3621225 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122624&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11144678 104015286 CHEMBL3621225 ZINC28085461 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417968 Cc1cc(C)cc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)c1 InChI=1S/C24H19NO2/c1-16-13-17(2)15-18(14-16)11-12-19-7-3-6-10-22(19)25-23(26)20-8-4-5-9-21(20)24(25)27/h3-15H,1-2H3/b12-11+ IGNWLZAEYVNZHK-VAWYXSNFSA-N 50122626 CHEMBL3623113 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122626&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10935381 85309721 CHEMBL3623113 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417969 CN1c2ccc(O)cc2C(=C)c2ccccc2C1=O InChI=1S/C16H13NO2/c1-10-12-5-3-4-6-13(12)16(19)17(2)15-8-7-11(18)9-14(10)15/h3-9,18H,1H2,2H3 VGQGXKVPVNOLEN-UHFFFAOYSA-N 50396601 CHEMBL2171902 Oxysterols receptor LXR-beta 11000 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396601&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71458918 163345625 CHEMBL2171902 ZINC95557279 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417970 COc1ccc(\C=C\c2ccccc2N2C(=O)c3ccccc3C2=O)cc1OC InChI=1S/C24H19NO4/c1-28-21-14-12-16(15-22(21)29-2)11-13-17-7-3-6-10-20(17)25-23(26)18-8-4-5-9-19(18)24(25)27/h3-15H,1-2H3/b13-11+ MKFOSSOUEAENMG-ACCUITESSA-N 50122619 CHEMBL3623107 Oxysterols receptor LXR-beta 1800 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122619&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 11080769 104015281 CHEMBL3623107 ZINC28091859 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50417975 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 66 ChEMBL 10.1021/acsmedchemlett.5b00170 10.7270/Q2VM4F2C 26288691 Nomura, S; Endo-Umeda, K; Aoyama, A; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50415887 Fc1ccc(cc1)S(=O)(=O)N1CCCc2ccc(NC(=O)c3c(F)cccc3F)cc12 InChI=1S/C22H17F3N2O3S/c23-15-7-10-17(11-8-15)31(29,30)27-12-2-3-14-6-9-16(13-20(14)27)26-22(28)21-18(24)4-1-5-19(21)25/h1,4-11,13H,2-3,12H2,(H,26,28) FVZFZUZUHQAGGY-UHFFFAOYSA-N 50121938 CHEMBL3617295 Oxysterols receptor LXR-beta 3200 ChEMBL 10.1016/j.bmcl.2015.08.028 10.7270/Q251411W 26321361 Fauber, BP; Gobbi, A; Savy, P; Burton, B; Deng, Y; Everett, C; La, H; Johnson, AR; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121938&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18565138 319566299 CHEMBL3617295 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50415894 Fc1ccc(cc1)S(=O)(=O)N1CCc2ccc(NC(=O)c3c(F)cccc3F)cc12 InChI=1S/C21H15F3N2O3S/c22-14-5-8-16(9-6-14)30(28,29)26-11-10-13-4-7-15(12-19(13)26)25-21(27)20-17(23)2-1-3-18(20)24/h1-9,12H,10-11H2,(H,25,27) GSOBXIVEUTZFSC-UHFFFAOYSA-N 50121939 CHEMBL3617297 Oxysterols receptor LXR-beta 5700 ChEMBL 10.1016/j.bmcl.2015.08.028 10.7270/Q251411W 26321361 Fauber, BP; Gobbi, A; Savy, P; Burton, B; Deng, Y; Everett, C; La, H; Johnson, AR; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122190169 319566300 CHEMBL3617297 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50416178 Fc1ccc(cc1)S(=O)(=O)N1CCCc2ccc(NC(=O)c3ccccc3Cl)cc12 InChI=1S/C22H18ClFN2O3S/c23-20-6-2-1-5-19(20)22(27)25-17-10-7-15-4-3-13-26(21(15)14-17)30(28,29)18-11-8-16(24)9-12-18/h1-2,5-12,14H,3-4,13H2,(H,25,27) LKFZKPRWHFURRD-UHFFFAOYSA-N 50121988 CHEMBL3617309 Oxysterols receptor LXR-beta 3800 ChEMBL 10.1016/j.bmcl.2015.08.028 10.7270/Q251411W 26321361 Fauber, BP; Gobbi, A; Savy, P; Burton, B; Deng, Y; Everett, C; La, H; Johnson, AR; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50121988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50121988&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18565134 319566309 CHEMBL3617309 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50416186 Fc1ccc(cc1)S(=O)(=O)N1CCCc2ccc(NC(=O)c3c(F)cccc3Cl)cc12 InChI=1S/C22H17ClF2N2O3S/c23-18-4-1-5-19(25)21(18)22(28)26-16-9-6-14-3-2-12-27(20(14)13-16)31(29,30)17-10-7-15(24)8-11-17/h1,4-11,13H,2-3,12H2,(H,26,28) YVMQUIHDHWLADX-UHFFFAOYSA-N 50044160 CHEMBL3314003 Oxysterols receptor LXR-beta 2600 ChEMBL 10.1016/j.bmcl.2015.08.028 10.7270/Q251411W 26321361 Fauber, BP; Gobbi, A; Savy, P; Burton, B; Deng, Y; Everett, C; La, H; Johnson, AR; Lockey, P; Norman, M; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044160&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 18565141 313068113 CHEMBL3314003 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50475186 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 230 ChEMBL 10.1016/j.bmcl.2016.02.031 10.7270/Q2R2138B 26905831 Toyama, H; Sato, S; Shirakawa, H; Komai, M; Hashimoto, Y; Fujii, S The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499818 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 390 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499822 C[C@H](CC[C@@H]1OC1(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H44O2/c1-17(6-11-24-25(2,3)29-24)21-9-10-22-20-8-7-18-16-19(28)12-14-26(18,4)23(20)13-15-27(21,22)5/h7,17,19-24,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,24+,26+,27-/m1/s1 OSENKJZWYQXHBN-XVYZBDJZSA-N 20164 (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-dimethyloxiran-2-yl]butan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::24(S),25-epoxycholesterol::CHEMBL434302::Epoxycholesterol Oxysterols receptor LXR-beta >20000 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20164&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search CO1 6XBM,1P8D,6OT0 3247059 49688239 CHEMBL434302 2751 C15632 ZINC06201930 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499823 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 5.0 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499824 CS(=O)(=O)c1cc(ccc1CO)-c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccccc2C(F)(F)F)s1 InChI=1S/C27H24F3NO5S3/c1-38(33,34)26-15-20(11-12-21(26)18-32)24-14-13-22(37-24)17-31(16-19-7-3-2-4-8-19)39(35,36)25-10-6-5-9-23(25)27(28,29)30/h2-15,32H,16-18H2,1H3 NLDOCDWHNYIGKV-UHFFFAOYSA-N 50177010 CHEMBL3814006 Oxysterols receptor LXR-beta 1.000000 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25210583 346549206 CHEMBL3814006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499829 C[C@H](CC[C@@H]1OC1(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H44O2/c1-17(6-11-24-25(2,3)29-24)21-9-10-22-20-8-7-18-16-19(28)12-14-26(18,4)23(20)13-15-27(21,22)5/h7,17,19-24,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,24+,26+,27-/m1/s1 OSENKJZWYQXHBN-XVYZBDJZSA-N 20164 (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2S)-3,3-dimethyloxiran-2-yl]butan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::24(S),25-epoxycholesterol::CHEMBL434302::Epoxycholesterol Oxysterols receptor LXR-beta 168 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20164&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search CO1 6XBM,1P8D,6OT0 3247059 49688239 CHEMBL434302 2751 C15632 ZINC06201930 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499830 CS(=O)(=O)c1cc(ccc1CO)-c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccccc2C(F)(F)F)s1 InChI=1S/C27H24F3NO5S3/c1-38(33,34)26-15-20(11-12-21(26)18-32)24-14-13-22(37-24)17-31(16-19-7-3-2-4-8-19)39(35,36)25-10-6-5-9-23(25)27(28,29)30/h2-15,32H,16-18H2,1H3 NLDOCDWHNYIGKV-UHFFFAOYSA-N 50177010 CHEMBL3814006 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25210583 346549206 CHEMBL3814006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499844 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3 CTCGRQVHZGKQJF-UHFFFAOYSA-N 50177013 CHEMBL3814372 Oxysterols receptor LXR-beta 1275 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127051155 346549209 CHEMBL3814372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499845 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3 CTCGRQVHZGKQJF-UHFFFAOYSA-N 50177013 CHEMBL3814372 Oxysterols receptor LXR-beta 1270 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127051155 346549209 CHEMBL3814372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499846 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3 CTCGRQVHZGKQJF-UHFFFAOYSA-N 50177013 CHEMBL3814372 Oxysterols receptor LXR-beta >2500 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127051155 346549209 CHEMBL3814372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499847 CS(=O)(=O)c1cccc(c1)N1CCN(C(C1)c1ccccc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H21F3N4O2S/c1-32(30,31)18-9-5-8-17(14-18)28-12-13-29(19(15-28)16-6-3-2-4-7-16)21-26-11-10-20(27-21)22(23,24)25/h2-11,14,19H,12-13,15H2,1H3 GWLPLKIBBKZUGZ-UHFFFAOYSA-N 50177014 CHEMBL3813875 Oxysterols receptor LXR-beta 94 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049312 346549210 CHEMBL3813875 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499848 CS(=O)(=O)c1cccc(c1)N1CCN(C(C1)c1ccccc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H21F3N4O2S/c1-32(30,31)18-9-5-8-17(14-18)28-12-13-29(19(15-28)16-6-3-2-4-7-16)21-26-11-10-20(27-21)22(23,24)25/h2-11,14,19H,12-13,15H2,1H3 GWLPLKIBBKZUGZ-UHFFFAOYSA-N 50177014 CHEMBL3813875 Oxysterols receptor LXR-beta 94.0 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049312 346549210 CHEMBL3813875 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499849 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O2S/c1-13(2)16-12-25(14-5-4-6-15(11-14)29(3,27)28)9-10-26(16)18-23-8-7-17(24-18)19(20,21)22/h4-8,11,13,16H,9-10,12H2,1-3H3/t16-/m0/s1 XVRHEEOCNTZUNF-INIZCTEOSA-N 50177011 CHEMBL3815014::US10144715, Compound 7-13 Oxysterols receptor LXR-beta 4.0 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049313 346549207 CHEMBL3815014 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499850 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(10-13)30(3,28)29)8-9-27(15)18-24-7-6-17(25-18)19(21,22)23/h4-7,10,12,15H,8-9,11H2,1-3H3/t15-/m0/s1 YTEDTWJJQBCOTI-HNNXBMFYSA-N 50177012 CHEMBL3814153::US10144715, Compound 7-32 Oxysterols receptor LXR-beta 1.000000 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883427 346549208 CHEMBL3814153 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499851 CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H21ClF4N4O2S/c1-11(2)15-10-27(12-4-5-14(21)16(8-12)31(3,29)30)6-7-28(15)18-25-9-13(20)17(26-18)19(22,23)24/h4-5,8-9,11,15H,6-7,10H2,1-3H3/t15-/m0/s1 SWVQEDYQXWDKTA-HNNXBMFYSA-N 50177016 CHEMBL3814501 Oxysterols receptor LXR-beta 1.000000 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177016&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883423 346549212 CHEMBL3814501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499852 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O3S/c1-12(2)16-10-27(14-4-5-15(21)17(8-14)32(3,30)31)6-7-28(16)19-25-9-13(11-29)18(26-19)20(22,23)24/h4-5,8-9,12,16,29H,6-7,10-11H2,1-3H3/t16-/m0/s1 QJGPMJDHZAMQSJ-INIZCTEOSA-N 50177017 CHEMBL3815001::US10144715, Compound 11-1 Oxysterols receptor LXR-beta 9.0 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177017&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883429 346549213 CHEMBL3815001 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499853 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28F4N4O3S/c1-13(2)17-12-29(14-6-7-16(23)18(10-14)34(5,32)33)8-9-30(17)20-27-11-15(21(3,4)31)19(28-20)22(24,25)26/h6-7,10-11,13,17,31H,8-9,12H2,1-5H3/t17-/m0/s1 HXOUVMGQDQYWNM-KRWDZBQOSA-N 50177018 CHEMBL3814478::US10144715, Compound 14-1 Oxysterols receptor LXR-beta 8.0 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883492 346549214 CHEMBL3814478 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499854 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m0/s1 FPVIRRAMNBCEDK-KRWDZBQOSA-N 50177015 CHEMBL3814206::US10144715, Compound 19-1 Oxysterols receptor LXR-beta 3.0 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 67S 5I4V 91827457 346549211 CHEMBL3814206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499855 CC(C)[C@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m1/s1 FPVIRRAMNBCEDK-QGZVFWFLSA-N 50177019 CHEMBL3813863::US10144715, Compound 19-2 Oxysterols receptor LXR-beta 160 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177019&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883505 346549215 CHEMBL3813863 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499856 CS(=O)(=O)c1cc(ccc1CO)-c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccccc2C(F)(F)F)s1 InChI=1S/C27H24F3NO5S3/c1-38(33,34)26-15-20(11-12-21(26)18-32)24-14-13-22(37-24)17-31(16-19-7-3-2-4-8-19)39(35,36)25-10-6-5-9-23(25)27(28,29)30/h2-15,32H,16-18H2,1H3 NLDOCDWHNYIGKV-UHFFFAOYSA-N 50177010 CHEMBL3814006 Oxysterols receptor LXR-beta 1.3 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25210583 346549206 CHEMBL3814006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499878 CS(=O)(=O)c1cc(ccc1CO)-c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccccc2C(F)(F)F)s1 InChI=1S/C27H24F3NO5S3/c1-38(33,34)26-15-20(11-12-21(26)18-32)24-14-13-22(37-24)17-31(16-19-7-3-2-4-8-19)39(35,36)25-10-6-5-9-23(25)27(28,29)30/h2-15,32H,16-18H2,1H3 NLDOCDWHNYIGKV-UHFFFAOYSA-N 50177010 CHEMBL3814006 Oxysterols receptor LXR-beta 0.600000 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25210583 346549206 CHEMBL3814006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499882 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3 CTCGRQVHZGKQJF-UHFFFAOYSA-N 50177013 CHEMBL3814372 Oxysterols receptor LXR-beta 2135 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127051155 346549209 CHEMBL3814372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499883 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3 CTCGRQVHZGKQJF-UHFFFAOYSA-N 50177013 CHEMBL3814372 Oxysterols receptor LXR-beta 2130 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127051155 346549209 CHEMBL3814372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499884 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3 CTCGRQVHZGKQJF-UHFFFAOYSA-N 50177013 CHEMBL3814372 Oxysterols receptor LXR-beta 990 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127051155 346549209 CHEMBL3814372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499885 FC(F)(F)c1ccc(CN2CCN(CC2c2ccccc2)c2ccccc2)cn1 InChI=1S/C23H22F3N3/c24-23(25,26)22-12-11-18(15-27-22)16-29-14-13-28(20-9-5-2-6-10-20)17-21(29)19-7-3-1-4-8-19/h1-12,15,21H,13-14,16-17H2 MGAXXAQFWJEKCP-UHFFFAOYSA-N 50177020 CHEMBL3815113 Oxysterols receptor LXR-beta >20000 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177020&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049311 346549216 CHEMBL3815113 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499886 CS(=O)(=O)c1cccc(c1)N1CCN(C(C1)c1ccccc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H21F3N4O2S/c1-32(30,31)18-9-5-8-17(14-18)28-12-13-29(19(15-28)16-6-3-2-4-7-16)21-26-11-10-20(27-21)22(23,24)25/h2-11,14,19H,12-13,15H2,1H3 GWLPLKIBBKZUGZ-UHFFFAOYSA-N 50177014 CHEMBL3813875 Oxysterols receptor LXR-beta 1289 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049312 346549210 CHEMBL3813875 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499887 CS(=O)(=O)c1cccc(c1)N1CCN(C(C1)c1ccccc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H21F3N4O2S/c1-32(30,31)18-9-5-8-17(14-18)28-12-13-29(19(15-28)16-6-3-2-4-7-16)21-26-11-10-20(27-21)22(23,24)25/h2-11,14,19H,12-13,15H2,1H3 GWLPLKIBBKZUGZ-UHFFFAOYSA-N 50177014 CHEMBL3813875 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049312 346549210 CHEMBL3813875 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499888 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O2S/c1-13(2)16-12-25(14-5-4-6-15(11-14)29(3,27)28)9-10-26(16)18-23-8-7-17(24-18)19(20,21)22/h4-8,11,13,16H,9-10,12H2,1-3H3/t16-/m0/s1 XVRHEEOCNTZUNF-INIZCTEOSA-N 50177011 CHEMBL3815014::US10144715, Compound 7-13 Oxysterols receptor LXR-beta 53 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049313 346549207 CHEMBL3815014 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499889 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(10-13)30(3,28)29)8-9-27(15)18-24-7-6-17(25-18)19(21,22)23/h4-7,10,12,15H,8-9,11H2,1-3H3/t15-/m0/s1 YTEDTWJJQBCOTI-HNNXBMFYSA-N 50177012 CHEMBL3814153::US10144715, Compound 7-32 Oxysterols receptor LXR-beta 53 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883427 346549208 CHEMBL3814153 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499890 CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H21ClF4N4O2S/c1-11(2)15-10-27(12-4-5-14(21)16(8-12)31(3,29)30)6-7-28(15)18-25-9-13(20)17(26-18)19(22,23)24/h4-5,8-9,11,15H,6-7,10H2,1-3H3/t15-/m0/s1 SWVQEDYQXWDKTA-HNNXBMFYSA-N 50177016 CHEMBL3814501 Oxysterols receptor LXR-beta 21 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177016&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883423 346549212 CHEMBL3814501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499891 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O3S/c1-12(2)16-10-27(14-4-5-15(21)17(8-14)32(3,30)31)6-7-28(16)19-25-9-13(11-29)18(26-19)20(22,23)24/h4-5,8-9,12,16,29H,6-7,10-11H2,1-3H3/t16-/m0/s1 QJGPMJDHZAMQSJ-INIZCTEOSA-N 50177017 CHEMBL3815001::US10144715, Compound 11-1 Oxysterols receptor LXR-beta 68 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177017&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883429 346549213 CHEMBL3815001 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499892 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28F4N4O3S/c1-13(2)17-12-29(14-6-7-16(23)18(10-14)34(5,32)33)8-9-30(17)20-27-11-15(21(3,4)31)19(28-20)22(24,25)26/h6-7,10-11,13,17,31H,8-9,12H2,1-5H3/t17-/m0/s1 HXOUVMGQDQYWNM-KRWDZBQOSA-N 50177018 CHEMBL3814478::US10144715, Compound 14-1 Oxysterols receptor LXR-beta 80 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883492 346549214 CHEMBL3814478 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499893 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m0/s1 FPVIRRAMNBCEDK-KRWDZBQOSA-N 50177015 CHEMBL3814206::US10144715, Compound 19-1 Oxysterols receptor LXR-beta 21 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 67S 5I4V 91827457 346549211 CHEMBL3814206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499894 CC(C)[C@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m1/s1 FPVIRRAMNBCEDK-QGZVFWFLSA-N 50177019 CHEMBL3813863::US10144715, Compound 19-2 Oxysterols receptor LXR-beta 503 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177019&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883505 346549215 CHEMBL3813863 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50499895 CS(=O)(=O)c1cc(ccc1CO)-c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccccc2C(F)(F)F)s1 InChI=1S/C27H24F3NO5S3/c1-38(33,34)26-15-20(11-12-21(26)18-32)24-14-13-22(37-24)17-31(16-19-7-3-2-4-8-19)39(35,36)25-10-6-5-9-23(25)27(28,29)30/h2-15,32H,16-18H2,1H3 NLDOCDWHNYIGKV-UHFFFAOYSA-N 50177010 CHEMBL3814006 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/acs.jmedchem.5b02029 10.7270/Q2XP76V7 26990539 Zheng, Y; Zhuang, L; Fan, KY; Tice, CM; Zhao, W; Dong, C; Lotesta, SD; Leftheris, K; Lindblom, PR; Liu, Z; Shimada, J; Noto, PB; Meng, S; Hardy, A; Howard, L; Krosky, P; Guo, J; Lipinski, K; Kandpal, G; Bukhtiyarov, Y; Zhao, Y; Lala, D; Van Orden, R; Zhou, J; Chen, G; Wu, Z; McKeever, BM; McGeehan, GM; Gregg, RE; Claremon, DA; Singh, SB Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25210583 346549206 CHEMBL3814006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 859986 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 50.0 US Patent 10.7270/Q2JW8H8C aid1804094 US10543183 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 859990 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 HNAJDMYOTDNOBK-UHFFFAOYSA-N 50204072 CHEMBL3945199::US10543183, Compound 12::US10945978, Compound 12 Oxysterols receptor LXR-beta 11.0 US Patent 10.7270/Q2JW8H8C aid1804094 US10543183 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6OX 5JY3 49787490 375980324 CHEMBL3945199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 859992 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3 JLPURTXCSILYLW-UHFFFAOYSA-N 50034775 CHEMBL3360975::US10543183, Compound 38::US10945978, Compound 38 Oxysterols receptor LXR-beta 630 US Patent 10.7270/Q2JW8H8C aid1804094 US10543183 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652 4RAK 59251511 313066503 CHEMBL3360975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497983 CN(C)C(=O)c1ccc(cc1Cl)-c1cnc(N2CCN(CC2)C(=O)[C@](O)(c2ccccc2)C(F)(F)F)c(c1)C#N InChI=1S/C28H25ClF3N5O3/c1-35(2)25(38)22-9-8-18(15-23(22)29)20-14-19(16-33)24(34-17-20)36-10-12-37(13-11-36)26(39)27(40,28(30,31)32)21-6-4-3-5-7-21/h3-9,14-15,17,40H,10-13H2,1-2H3/t27-/m1/s1 LULNTXWHXDXKNP-HHHXNRCGSA-N 50172624 CHEMBL3809494 Oxysterols receptor LXR-beta 8 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172624&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127044456 104058679 CHEMBL3809494 ZINC28525755 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497984 CC(C)[C@](O)(C(=O)N1CCC(CC1)C1CCN(CC1)c1ccc(C(=O)N(C)C)c(Cl)c1)C(F)(F)F InChI=1S/C25H35ClF3N3O3/c1-16(2)24(35,25(27,28)29)23(34)32-13-9-18(10-14-32)17-7-11-31(12-8-17)19-5-6-20(21(26)15-19)22(33)30(3)4/h5-6,15-18,35H,7-14H2,1-4H3/t24-/m0/s1 POYRTHYMXFSQBJ-DEOSSOPVSA-N 50172505 CHEMBL3809555 Oxysterols receptor LXR-beta 840 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172505&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127044780 104058560 CHEMBL3809555 ZINC26257986 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497990 CN(C)C(=O)c1ccc(cc1Cl)N1CCC(CC1)C1CCN(CC1)C(=O)[C@](O)(c1ccccc1)C(F)(F)F InChI=1S/C28H33ClF3N3O3/c1-33(2)25(36)23-9-8-22(18-24(23)29)34-14-10-19(11-15-34)20-12-16-35(17-13-20)26(37)27(38,28(30,31)32)21-6-4-3-5-7-21/h3-9,18-20,38H,10-17H2,1-2H3/t27-/m1/s1 JFGUQJWIGPIGJG-HHHXNRCGSA-N 50172538 CHEMBL3808992 Oxysterols receptor LXR-beta 550 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172538&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127044605 104058593 9468 CHEMBL3808992 ZINC01530811 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497991 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 20 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497992 CN(C)C(=O)c1ccc(cc1Cl)-c1cnc(N2CCN(CC2)C(=O)OC(C)(C)C)c(c1)C#N InChI=1S/C24H28ClN5O3/c1-24(2,3)33-23(32)30-10-8-29(9-11-30)21-17(14-26)12-18(15-27-21)16-6-7-19(20(25)13-16)22(31)28(4)5/h6-7,12-13,15H,8-11H2,1-5H3 GGBFPOANZPHQBF-UHFFFAOYSA-N 50172646 CHEMBL3809583 Oxysterols receptor LXR-beta 940 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172646&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127044455 104058701 CHEMBL3809583 ZINC28522512 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497993 CN(C)C(=O)c1ccc(cc1Cl)-c1cnc(N2CCN(CC2)C(=O)OC(C)(C)C)c(c1)C#N InChI=1S/C24H28ClN5O3/c1-24(2,3)33-23(32)30-10-8-29(9-11-30)21-17(14-26)12-18(15-27-21)16-6-7-19(20(25)13-16)22(31)28(4)5/h6-7,12-13,15H,8-11H2,1-5H3 GGBFPOANZPHQBF-UHFFFAOYSA-N 50172646 CHEMBL3809583 Oxysterols receptor LXR-beta 770 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172646&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127044455 104058701 CHEMBL3809583 ZINC28522512 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497994 CN(C)C(=O)c1ccc(cc1Cl)-c1cnc(N2CCN(CC2)C(=O)[C@](O)(c2ccccc2)C(F)(F)F)c(c1)C#N InChI=1S/C28H25ClF3N5O3/c1-35(2)25(38)22-9-8-18(15-23(22)29)20-14-19(16-33)24(34-17-20)36-10-12-37(13-11-36)26(39)27(40,28(30,31)32)21-6-4-3-5-7-21/h3-9,14-15,17,40H,10-13H2,1-2H3/t27-/m1/s1 LULNTXWHXDXKNP-HHHXNRCGSA-N 50172624 CHEMBL3809494 Oxysterols receptor LXR-beta 7 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172624&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127044456 104058679 CHEMBL3809494 ZINC28525755 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50497996 CC(C)[C@@](O)(C(=O)N1CCC(CC1)C1CCN(CC1)c1ccc(C(=O)N(C)C)c(Cl)c1)C(F)(F)F InChI=1S/C25H35ClF3N3O3/c1-16(2)24(35,25(27,28)29)23(34)32-13-9-18(10-14-32)17-7-11-31(12-8-17)19-5-6-20(21(26)15-19)22(33)30(3)4/h5-6,15-18,35H,7-14H2,1-4H3/t24-/m1/s1 POYRTHYMXFSQBJ-XMMPIXPASA-N 50172521 CHEMBL3809850 Oxysterols receptor LXR-beta 30 ChEMBL 10.1021/acs.jmedchem.6b00176 10.7270/Q2KP843T 27011007 Stachel, SJ; Zerbinatti, C; Rudd, MT; Cosden, M; Suon, S; Nanda, KK; Wessner, K; DiMuzio, J; Maxwell, J; Wu, Z; Uslaner, JM; Michener, MS; Szczerba, P; Brnardic, E; Rada, V; Kim, Y; Meissner, R; Wuelfing, P; Yuan, Y; Ballard, J; Holahan, M; Klein, DJ; Lu, J; Fradera, X; Parthasarathy, G; Uebele, VN; Chen, Z; Li, Y; Li, J; Cooke, AJ; Bennett, DJ; Bilodeau, MT; Renger, J WuXi AppTec Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172521&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 668 5HJP,5HJS 118987028 104058576 CHEMBL3809850 ZINC03789195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501105 CCCc1c(OCCCCN2C(=O)NC(C)(C2=O)c2ccc(OC)cc2)ccc2c(cc(=O)oc12)C(F)(F)F InChI=1S/C28H29F3N2O6/c1-4-7-20-22(13-12-19-21(28(29,30)31)16-23(34)39-24(19)20)38-15-6-5-14-33-25(35)27(2,32-26(33)36)17-8-10-18(37-3)11-9-17/h8-13,16H,4-7,14-15H2,1-3H3,(H,32,36) ABUHBGNGKQNACH-UHFFFAOYSA-N 50064330 CHEMBL3403710 Oxysterols receptor LXR-beta 1400 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064330&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 44217616 313071266 CHEMBL3403710 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501106 CCCc1cc(cc(CCC)c1OCCCCN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H40F6N2O5/c1-6-10-21-18-24(30(43,31(33,34)35)32(36,37)38)19-22(11-7-2)26(21)44-17-9-8-16-40-27(41)29(5,39-28(40)42)23-12-14-25(15-13-23)45-20(3)4/h12-15,18-20,43H,6-11,16-17H2,1-5H3,(H,39,42) DFZLKVIVVZKYKP-UHFFFAOYSA-N 50094851 CHEMBL3589803 Oxysterols receptor LXR-beta 1150 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094851&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 56589730 103992714 CHEMBL3589803 ZINC13835708 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501107 CCCc1cc(cc(CCC)c1OC\C=C\CN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H38F6N2O5/c1-6-10-21-18-24(30(43,31(33,34)35)32(36,37)38)19-22(11-7-2)26(21)44-17-9-8-16-40-27(41)29(5,39-28(40)42)23-12-14-25(15-13-23)45-20(3)4/h8-9,12-15,18-20,43H,6-7,10-11,16-17H2,1-5H3,(H,39,42)/b9-8+ SBBYIMLVDJCKGK-CMDGGOBGSA-N 50172720 CHEMBL3814017 Oxysterols receptor LXR-beta 800 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172720&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 87123143 346548708 CHEMBL3814017 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501108 CCCc1cc(cc(CCC)c1OCC#CCN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H36F6N2O5/c1-6-10-21-18-24(30(43,31(33,34)35)32(36,37)38)19-22(11-7-2)26(21)44-17-9-8-16-40-27(41)29(5,39-28(40)42)23-12-14-25(15-13-23)45-20(3)4/h12-15,18-20,43H,6-7,10-11,16-17H2,1-5H3,(H,39,42) QVKMDRUNJHXGND-UHFFFAOYSA-N 50172721 CHEMBL3814026 Oxysterols receptor LXR-beta 610 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172721&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59234986 346548709 CHEMBL3814026 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501109 CCCc1cc(ccc1Oc1cccc(CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H32F6N2O5/c1-5-7-21-17-23(30(43,31(33,34)35)32(36,37)38)12-15-26(21)45-25-9-6-8-20(16-25)18-40-27(41)29(4,39-28(40)42)22-10-13-24(14-11-22)44-19(2)3/h6,8-17,19,43H,5,7,18H2,1-4H3,(H,39,42) JMPKDJGMMZUDBG-UHFFFAOYSA-N 50173929 CHEMBL3814025 Oxysterols receptor LXR-beta 500 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173929&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201075 104059777 CHEMBL3814025 ZINC28528610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501110 CCCc1cc(ccc1Oc1ccc(CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H32F6N2O5/c1-5-6-21-17-23(30(43,31(33,34)35)32(36,37)38)11-16-26(21)45-25-12-7-20(8-13-25)18-40-27(41)29(4,39-28(40)42)22-9-14-24(15-10-22)44-19(2)3/h7-17,19,43H,5-6,18H2,1-4H3,(H,39,42) SRRYEWKQTKBUQA-UHFFFAOYSA-N 50179486 CHEMBL3814224 Oxysterols receptor LXR-beta 1810 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179486&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201095 104064647 CHEMBL3814224 ZINC28570843 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501111 CCCc1cc(ccc1Oc1cccc(CCN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C33H34F6N2O5/c1-5-7-22-19-24(31(44,32(34,35)36)33(37,38)39)12-15-27(22)46-26-9-6-8-21(18-26)16-17-41-28(42)30(4,40-29(41)43)23-10-13-25(14-11-23)45-20(2)3/h6,8-15,18-20,44H,5,7,16-17H2,1-4H3,(H,40,43) HCAQPWPAUIJXRT-UHFFFAOYSA-N 50174995 CHEMBL3814000 Oxysterols receptor LXR-beta 2850 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174995&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59200986 346549007 CHEMBL3814000 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501112 CCCc1cc(ccc1Oc1ccc(CCN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C33H34F6N2O5/c1-5-6-22-19-24(31(44,32(34,35)36)33(37,38)39)11-16-27(22)46-26-12-7-21(8-13-26)17-18-41-28(42)30(4,40-29(41)43)23-9-14-25(15-10-23)45-20(2)3/h7-16,19-20,44H,5-6,17-18H2,1-4H3,(H,40,43) AGGRXWJTRGYHGV-UHFFFAOYSA-N 50179488 CHEMBL3814807 Oxysterols receptor LXR-beta 1880 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179488&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59200932 104064649 CHEMBL3814807 ZINC28570665 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501113 CCCc1cc(ccc1Oc1ccc(CCN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c(C)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C34H36F6N2O5/c1-6-7-23-19-25(32(45,33(35,36)37)34(38,39)40)11-15-28(23)47-27-12-8-22(21(4)18-27)16-17-42-29(43)31(5,41-30(42)44)24-9-13-26(14-10-24)46-20(2)3/h8-15,18-20,45H,6-7,16-17H2,1-5H3,(H,41,44) JDMOAMFFFMHAGP-UHFFFAOYSA-N 50176997 CHEMBL3814071 Oxysterols receptor LXR-beta 700 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176997&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59200977 346549193 CHEMBL3814071 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501114 CCCc1cc(ccc1Oc1ccc(CCN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c(OC)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C34H36F6N2O6/c1-6-7-22-18-24(32(45,33(35,36)37)34(38,39)40)11-15-27(22)48-26-12-8-21(28(19-26)46-5)16-17-42-29(43)31(4,41-30(42)44)23-9-13-25(14-10-23)47-20(2)3/h8-15,18-20,45H,6-7,16-17H2,1-5H3,(H,41,44) QHZVQRNIGBTKBS-UHFFFAOYSA-N 50179489 CHEMBL3814297 Oxysterols receptor LXR-beta 1660 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179489&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201030 104064650 CHEMBL3814297 ZINC28570475 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501115 CCCc1cc(ccc1Oc1ccc(CCN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c(O)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C33H34F6N2O6/c1-5-6-21-17-23(31(45,32(34,35)36)33(37,38)39)10-14-27(21)47-25-11-7-20(26(42)18-25)15-16-41-28(43)30(4,40-29(41)44)22-8-12-24(13-9-22)46-19(2)3/h7-14,17-19,42,45H,5-6,15-16H2,1-4H3,(H,40,44) FCPBHZWBYHJLGZ-UHFFFAOYSA-N 50179490 CHEMBL3813961 Oxysterols receptor LXR-beta 2870 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179490&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59200935 104064651 CHEMBL3813961 ZINC28570759 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501116 CCCc1cc(ccc1Oc1ccc(cc1)C(O)CN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C33H34F6N2O6/c1-5-6-21-17-23(31(45,32(34,35)36)33(37,38)39)11-16-27(21)47-25-12-7-20(8-13-25)26(42)18-41-28(43)30(4,40-29(41)44)22-9-14-24(15-10-22)46-19(2)3/h7-17,19,26,42,45H,5-6,18H2,1-4H3,(H,40,44) NUKARMLSXBVHLP-UHFFFAOYSA-N 50179491 CHEMBL3814806 Oxysterols receptor LXR-beta 2330 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179491&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127052439 104064652 CHEMBL3814806 ZINC28569861 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501117 CCCc1cc(ccc1Oc1ccc(cc1)C(=O)CN1C(=O)NC(C)(C1=O)c1ccc(OC(C)C)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C33H32F6N2O6/c1-5-6-21-17-23(31(45,32(34,35)36)33(37,38)39)11-16-27(21)47-25-12-7-20(8-13-25)26(42)18-41-28(43)30(4,40-29(41)44)22-9-14-24(15-10-22)46-19(2)3/h7-17,19,45H,5-6,18H2,1-4H3,(H,40,44) HITJSXNGOCIANZ-UHFFFAOYSA-N 50179403 CHEMBL3814381 Oxysterols receptor LXR-beta 120 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179403&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201131 346549578 CHEMBL3814381 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501118 CCCc1cc(ccc1Oc1ccc(C(=O)CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c(C)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C34H34F6N2O6/c1-6-7-21-17-23(32(46,33(35,36)37)34(38,39)40)10-15-28(21)48-25-13-14-26(20(4)16-25)27(43)18-42-29(44)31(5,41-30(42)45)22-8-11-24(12-9-22)47-19(2)3/h8-17,19,46H,6-7,18H2,1-5H3,(H,41,45) ITSLAZZKGMATKG-UHFFFAOYSA-N 50179430 CHEMBL3813703 Oxysterols receptor LXR-beta 64 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179430&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 72529513 346549590 CHEMBL3813703 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501119 CCCc1cc(ccc1Oc1ccc(C(=O)CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c(OC)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C34H34F6N2O7/c1-6-7-20-16-22(32(46,33(35,36)37)34(38,39)40)10-15-27(20)49-24-13-14-25(28(17-24)47-5)26(43)18-42-29(44)31(4,41-30(42)45)21-8-11-23(12-9-21)48-19(2)3/h8-17,19,46H,6-7,18H2,1-5H3,(H,41,45) VIBZMEWMIKJKPT-UHFFFAOYSA-N 50179431 CHEMBL3814351 Oxysterols receptor LXR-beta 360 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179431&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 87198339 346549591 CHEMBL3814351 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501120 CCCc1cc(ccc1Oc1ccc(C(=O)CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cc2)c(O)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C33H32F6N2O7/c1-5-6-19-15-21(31(46,32(34,35)36)33(37,38)39)9-14-27(19)48-23-12-13-24(25(42)16-23)26(43)17-41-28(44)30(4,40-29(41)45)20-7-10-22(11-8-20)47-18(2)3/h7-16,18,42,46H,5-6,17H2,1-4H3,(H,40,45) CINWDGRLSZBYBJ-UHFFFAOYSA-N 50179484 CHEMBL3814980 Oxysterols receptor LXR-beta 110 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179484&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201087 104064645 CHEMBL3814980 ZINC28569566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501121 CCCc1cc(ccc1Oc1ccc(C(=O)CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cn2)c(O)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H31F6N3O7/c1-5-6-18-13-19(30(46,31(33,34)35)32(36,37)38)7-11-25(18)48-20-8-10-22(23(42)14-20)24(43)16-41-27(44)29(4,40-28(41)45)26-12-9-21(15-39-26)47-17(2)3/h7-15,17,42,46H,5-6,16H2,1-4H3,(H,40,45) PFNIPVRYLSNESB-UHFFFAOYSA-N 50179485 CHEMBL3814799 Oxysterols receptor LXR-beta 58 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179485&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201115 104064646 CHEMBL3814799 ZINC28570826 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501122 CCCc1cc(ccc1Oc1ccc(C(=O)CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cn2)c(O)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H31F6N3O7/c1-5-6-18-13-19(30(46,31(33,34)35)32(36,37)38)7-11-25(18)48-20-8-10-22(23(42)14-20)24(43)16-41-27(44)29(4,40-28(41)45)26-12-9-21(15-39-26)47-17(2)3/h7-15,17,42,46H,5-6,16H2,1-4H3,(H,40,45) PFNIPVRYLSNESB-UHFFFAOYSA-N 50179485 CHEMBL3814799 Oxysterols receptor LXR-beta 58.0 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179485&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201115 104064646 CHEMBL3814799 ZINC28570826 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501123 CCCc1cc(ccc1Oc1ccc(C(=O)CN2C(=O)NC(C)(C2=O)c2ccc(OC(C)C)cn2)c(O)c1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C32H31F6N3O7/c1-5-6-18-13-19(30(46,31(33,34)35)32(36,37)38)7-11-25(18)48-20-8-10-22(23(42)14-20)24(43)16-41-27(44)29(4,40-28(41)45)26-12-9-21(15-39-26)47-17(2)3/h7-15,17,42,46H,5-6,16H2,1-4H3,(H,40,45) PFNIPVRYLSNESB-UHFFFAOYSA-N 50179485 CHEMBL3814799 Oxysterols receptor LXR-beta 7.00 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179485&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59201115 104064646 CHEMBL3814799 ZINC28570826 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50501124 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 410 ChEMBL 10.1016/j.bmc.2016.05.048 10.7270/Q2DJ5HJ4 27283790 Koura, M; Yamaguchi, Y; Kurobuchi, S; Sumida, H; Watanabe, Y; Enomoto, T; Matsuda, T; Okuda, A; Koshizawa, T; Matsumoto, Y; Shibuya, K Kowa Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1007232 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 40.0 US Patent 10.7270/Q2959MPZ aid1805335 US10945978 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51085926 CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C17H15F6NO3S/c1-2-24(28(26,27)14-6-4-3-5-7-14)13-10-8-12(9-11-13)15(25,16(18,19)20)17(21,22)23/h3-11,25H,2H2,1H3 IVNRPSKTRKQRGY-UHFFFAOYSA-N 50426729 CHEMBL2326845 Oxysterols receptor LXR-beta 246 ChEMBL 10.1016/j.bmcl.2013.10.054 10.7270/Q2474CBT 24239186 Fauber, BP; de Leon Boenig, G; Burton, B; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Rene, O; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50426729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50426729&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 20704150 164155604 CHEMBL2326845 ZINC95581430 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51085927 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H11F10NO3S/c18-11-3-7-13(8-4-11)32(30,31)28(9-14(19,20)21)12-5-1-10(2-6-12)15(29,16(22,23)24)17(25,26)27/h1-8,29H,9H2 XCJCRDUPVLFMDD-UHFFFAOYSA-N 50444333 CHEMBL3094369 Oxysterols receptor LXR-beta 385 ChEMBL 10.1016/j.bmcl.2013.10.054 10.7270/Q2474CBT 24239186 Fauber, BP; de Leon Boenig, G; Burton, B; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Rene, O; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50444333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50444333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 72722945 194942229 CHEMBL3094369 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51085928 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccc(cc1)C#N)(C(F)(F)F)C(F)(F)F InChI=1S/C18H11F9N2O3S/c19-15(20,21)10-29(33(31,32)14-7-1-11(9-28)2-8-14)13-5-3-12(4-6-13)16(30,17(22,23)24)18(25,26)27/h1-8,30H,10H2 RTHMHPHETQFWGP-UHFFFAOYSA-N 50444335 CHEMBL3094367 Oxysterols receptor LXR-beta 902 ChEMBL 10.1016/j.bmcl.2013.10.054 10.7270/Q2474CBT 24239186 Fauber, BP; de Leon Boenig, G; Burton, B; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Rene, O; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50444335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50444335&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 72722807 194942231 CHEMBL3094367 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51085929 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 156 ChEMBL 10.1016/j.bmcl.2013.10.054 10.7270/Q2474CBT 24239186 Fauber, BP; de Leon Boenig, G; Burton, B; Eidenschenk, C; Everett, C; Gobbi, A; Hymowitz, SG; Johnson, AR; Liimatta, M; Lockey, P; Norman, M; Ouyang, W; Rene, O; Wong, H Genentech http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519327 CC(C)C1N(Cc2cn(nc12)-c1ccc(CO)c(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-12(2)19-18-15(8-29(19)21-26-7-14(11-32)20(27-21)22(23,24)25)9-30(28-18)16-5-4-13(10-31)17(6-16)35(3,33)34/h4-7,9,12,19,31-32H,8,10-11H2,1-3H3 HFGCUOYYZKNQLX-UHFFFAOYSA-N 50192751 CHEMBL3889601 Oxysterols receptor LXR-beta 273 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134131424 375075931 CHEMBL3889601 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519328 COc1ncnc(N2Cc3cn(nc3[C@H]2C(C)C)-c2cccc(c2)S(C)(=O)=O)c1F InChI=1S/C20H22FN5O3S/c1-12(2)18-17-13(9-25(18)19-16(21)20(29-3)23-11-22-19)10-26(24-17)14-6-5-7-15(8-14)30(4,27)28/h5-8,10-12,18H,9H2,1-4H3/t18-/m1/s1 XOTHLYNSDMSVGX-GOSISDBHSA-N 50192752 CHEMBL3905741 Oxysterols receptor LXR-beta 17 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134135247 375075932 CHEMBL3905741 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519334 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C21H22F3N5O3S/c1-12(2)18-17-14(10-29(27-17)15-5-4-6-16(7-15)33(3,31)32)9-28(18)20-25-8-13(11-30)19(26-20)21(22,23)24/h4-8,10,12,18,30H,9,11H2,1-3H3/t18-/m1/s1 NCZXBZJVJRJUSC-GOSISDBHSA-N 50192756 CHEMBL3932169 Oxysterols receptor LXR-beta 6.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6Y4 5KYA 121596966 375075935 CHEMBL3932169 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519335 COc1cc(nc(C)n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C21H25N5O3S/c1-13(2)21-20-15(11-25(21)18-10-19(29-4)23-14(3)22-18)12-26(24-20)16-7-6-8-17(9-16)30(5,27)28/h6-10,12-13,21H,11H2,1-5H3/t21-/m1/s1 VSLBVBOGQLFVOY-OAQYLSRUSA-N 50192757 CHEMBL3914727 Oxysterols receptor LXR-beta 4.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192757&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134142943 375075936 CHEMBL3914727 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519338 COc1cc(cc(C)n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C22H26N4O3S/c1-14(2)22-21-16(12-25(22)18-9-15(3)23-20(11-18)29-4)13-26(24-21)17-7-6-8-19(10-17)30(5,27)28/h6-11,13-14,22H,12H2,1-5H3/t22-/m1/s1 LNVWYDLYTZAVJQ-JOCHJYFZSA-N 50192758 CHEMBL3976470 Oxysterols receptor LXR-beta 6.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192758&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134151855 375075937 CHEMBL3976470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519342 COc1ncc(F)c(n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C20H22FN5O3S/c1-12(2)18-17-13(10-25(18)19-16(21)9-22-20(23-19)29-3)11-26(24-17)14-6-5-7-15(8-14)30(4,27)28/h5-9,11-12,18H,10H2,1-4H3/t18-/m1/s1 HDDKTNCZLILPNB-GOSISDBHSA-N 50192760 CHEMBL3972392 Oxysterols receptor LXR-beta 13 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6Y8 5KYJ 121596967 375075939 CHEMBL3972392 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519344 CC(C)[C@H]1N(Cc2cn(nc12)-c1ccc(CO)c(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-12(2)19-18-15(8-29(19)21-26-7-14(11-32)20(27-21)22(23,24)25)9-30(28-18)16-5-4-13(10-31)17(6-16)35(3,33)34/h4-7,9,12,19,31-32H,8,10-11H2,1-3H3/t19-/m1/s1 HFGCUOYYZKNQLX-LJQANCHMSA-N 50192761 CHEMBL3978980 Oxysterols receptor LXR-beta 6.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192761&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134151534 375075940 CHEMBL3978980 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519358 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 17 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519359 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m0/s1 FPVIRRAMNBCEDK-KRWDZBQOSA-N 50177015 CHEMBL3814206::US10144715, Compound 19-1 Oxysterols receptor LXR-beta 3.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 67S 5I4V 91827457 346549211 CHEMBL3814206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519360 CC(C)C1N(Cc2cn(nc12)-c1ccc(CO)c(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-12(2)19-18-15(8-29(19)21-26-7-14(11-32)20(27-21)22(23,24)25)9-30(28-18)16-5-4-13(10-31)17(6-16)35(3,33)34/h4-7,9,12,19,31-32H,8,10-11H2,1-3H3 HFGCUOYYZKNQLX-UHFFFAOYSA-N 50192751 CHEMBL3889601 Oxysterols receptor LXR-beta 26.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134131424 375075931 CHEMBL3889601 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519362 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1cc(nc(C)n1)C(F)(F)F InChI=1S/C21H22F3N5O2S/c1-12(2)20-19-14(10-28(20)18-9-17(21(22,23)24)25-13(3)26-18)11-29(27-19)15-6-5-7-16(8-15)32(4,30)31/h5-9,11-12,20H,10H2,1-4H3/t20-/m1/s1 IGGSXCWSHVYVMA-HXUWFJFHSA-N 50192753 CHEMBL3985591 Oxysterols receptor LXR-beta 3.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search TAC 2HCJ,2UXO,3Q5P,1I97,5J5B,2HDN,5J7L,6FPL,6FPM,2VKE,2TRT,1HNW,4B3A,4V9A 134157776 104075582 CHEMBL3985591 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519363 COc1cc(ccn1)N1Cc2cn(nc2[C@H]1C(C)(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C22H26N4O3S/c1-22(2,3)21-20-15(13-25(21)16-9-10-23-19(12-16)29-4)14-26(24-20)17-7-6-8-18(11-17)30(5,27)28/h6-12,14,21H,13H2,1-5H3/t21-/m0/s1 XOPXTKOQXWMGEF-NRFANRHFSA-N 50192750 CHEMBL3940521 Oxysterols receptor LXR-beta 5.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134145788 375075930 CHEMBL3940521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519370 CC(C)[C@H]1N(Cc2cn(nc12)-c1ccc(CO)c(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-12(2)19-18-15(8-29(19)21-26-7-14(11-32)20(27-21)22(23,24)25)9-30(28-18)16-5-4-13(10-31)17(6-16)35(3,33)34/h4-7,9,12,19,31-32H,8,10-11H2,1-3H3/t19-/m1/s1 HFGCUOYYZKNQLX-LJQANCHMSA-N 50192761 CHEMBL3978980 Oxysterols receptor LXR-beta 36 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192761&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134151534 375075940 CHEMBL3978980 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519371 CC(C)C1N(Cc2cn(nc12)-c1ccc(CO)c(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-12(2)19-18-15(8-29(19)21-26-7-14(11-32)20(27-21)22(23,24)25)9-30(28-18)16-5-4-13(10-31)17(6-16)35(3,33)34/h4-7,9,12,19,31-32H,8,10-11H2,1-3H3 HFGCUOYYZKNQLX-UHFFFAOYSA-N 50192751 CHEMBL3889601 Oxysterols receptor LXR-beta 273 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134131424 375075931 CHEMBL3889601 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238660 Cc1ccc(cc1Cl)N=CC(C(=O)c1ccco1)C(=O)C(F)(F)F InChI=1S/C16H11ClF3NO3/c1-9-4-5-10(7-12(9)17)21-8-11(15(23)16(18,19)20)14(22)13-3-2-6-24-13/h2-8,11H,1H3 OYFMGFGMRVOLQB-UHFFFAOYSA-N 93778 (2Z)-2-[(3-chloro-4-methyl-anilino)methylene]-4,4,4-trifluoro-1-(2-furyl)butane-1,3-dione::(2Z)-2-[(3-chloro-4-methylanilino)methylidene]-4,4,4-trifluoro-1-(2-furanyl)butane-1,3-dione::(2Z)-2-[(3-chloro-4-methylanilino)methylidene]-4,4,4-trifluoro-1-(furan-2-yl)butane-1,3-dione::(2Z)-2-[[(3-chloranyl-4-methyl-phenyl)amino]methylidene]-4,4,4-tris(fluoranyl)-1-(furan-2-yl)butane-1,3-dione::2-{[(3-chloro-4-methylphenyl)amino]methylene}-4,4,4-trifluoro-1-(2-furyl)-1,3-butanedione::MLS000579302::SMR000198583::cid_2149945 Oxysterols receptor LXR-beta 67525 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93778&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899513 164035022 ZINC02712757 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238668 O=C(N\N=C\c1cn(nc1-c1cc2ccccc2o1)-c1ccccc1)c1cccnc1 InChI=1S/C24H17N5O2/c30-24(18-8-6-12-25-14-18)27-26-15-19-16-29(20-9-2-1-3-10-20)28-23(19)22-13-17-7-4-5-11-21(17)31-22/h1-16H,(H,27,30)/b26-15+ CAEZKMVXBNAAGV-CVKSISIWSA-N 96047 MLS000334786::N-[(E)-[3-(1-benzofuran-2-yl)-1-phenyl-pyrazol-4-yl]methylideneamino]pyridine-3-carboxamide::N-[(E)-[3-(1-benzofuran-2-yl)-1-phenylpyrazol-4-yl]methylideneamino]pyridine-3-carboxamide::N-[(E)-[3-(2-benzofuranyl)-1-phenyl-4-pyrazolyl]methylideneamino]-3-pyridinecarboxamide::N-[(E)-[3-(benzofuran-2-yl)-1-phenyl-pyrazol-4-yl]methyleneamino]nicotinamide::SMR000249544::cid_6905845 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96047&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6905845 164037291 ZINC03333723 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238736 CSc1ccc(cc1)C1=NNC(S1)c1ccccc1 InChI=1S/C15H14N2S2/c1-18-13-9-7-12(8-10-13)15-17-16-14(19-15)11-5-3-2-4-6-11/h2-10,14,16H,1H3 GLWKBSNAEGRZSA-UHFFFAOYSA-N 114783 2-(4-methylsulfanylphenyl)-5-phenyl-2,3-dihydro-1,3,4-thiadiazole::2-[4-(methylthio)phenyl]-5-phenyl-2,3-dihydro-1,3,4-thiadiazole::MLS001179601::SMR000476244::cid_4570467::methyl4-(5-phenyl-2,3-dihydro-1,3,4-thiadiazol-2-yl)phenylsulfide Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114783&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899733 252664256 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238743 CC(=NN=C(C)c1cccs1)c1cccs1 InChI=1S/C12H12N2S2/c1-9(11-5-3-7-15-11)13-14-10(2)12-6-4-8-16-12/h3-8H,1-2H3 CVPWLODMVVPHSM-UHFFFAOYSA-N 114788 (Z)-1-(2-thienyl)ethylidene-[(Z)-1-(2-thienyl)ethylideneamino]amine::(Z)-1-thiophen-2-yl-N-[(Z)-1-thiophen-2-ylethylideneamino]ethanimine::MLS001207172::N,N'-Bis-(1-thiophen-2-yl-ethylidene)-hydrazine::SMR000505187::cid_5405580 Oxysterols receptor LXR-beta 67581 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114788&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5405580 252664261 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238812 CCOC(=O)c1cc(oc1C)-c1cccc(O)c1 InChI=1S/C14H14O4/c1-3-17-14(16)12-8-13(18-9(12)2)10-5-4-6-11(15)7-10/h4-8,15H,3H2,1-2H3 AUTTXECRJHAICF-UHFFFAOYSA-N 114831 5-(3-hydroxyphenyl)-2-methyl-3-furancarboxylic acid ethyl ester::5-(3-hydroxyphenyl)-2-methyl-furan-3-carboxylic acid ethyl ester::MLS003593241::SMR002253386::cid_53301705::ethyl 5-(3-hydroxyphenyl)-2-methyl-furan-3-carboxylate::ethyl 5-(3-hydroxyphenyl)-2-methylfuran-3-carboxylate Oxysterols receptor LXR-beta 67520 PubChem 10.7270/Q23F4N80 aid743037 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114831&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 53301705 252664302 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238820 O=c1[nH]cnc2cc(sc12)-c1ccccc1 InChI=1S/C12H8N2OS/c15-12-11-9(13-7-14-12)6-10(16-11)8-4-2-1-3-5-8/h1-7H,(H,13,14,15) XSAILWORLBSSMS-UHFFFAOYSA-N 114965 6-phenyl-1H-thieno[3,2-d]pyrimidin-4-one::CHEMBL381518::MLS000036657::SMR000035281::cid_661437 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114965&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 661437 252664427 CHEMBL381518 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238891 COc1ccccc1C=NN=C(N)c1ccccn1 InChI=1S/C14H14N4O/c1-19-13-8-3-2-6-11(13)10-17-18-14(15)12-7-4-5-9-16-12/h2-10H,1H3,(H2,15,18) SELWMUSSOZDBSJ-UHFFFAOYSA-N 114997 MLS000698346::N'-(2-methoxybenzylidene)-2-pyridinecarboximidohydrazide::N'-[(Z)-(2-methoxyphenyl)methylideneamino]-2-pyridinecarboximidamide::N'-[(Z)-(2-methoxyphenyl)methylideneamino]pyridine-2-carboximidamide::N'-[(Z)-o-anisylideneamino]picolinamidine::SMR000226343::cid_5568682 Oxysterols receptor LXR-beta 67622 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114997&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5568682 252664458 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238898 Cc1nn(c(Cl)c1CN=Nc1ccc(Cl)c(c1)C(O)=O)-c1ccccc1 InChI=1S/C18H14Cl2N4O2/c1-11-15(17(20)24(23-11)13-5-3-2-4-6-13)10-21-22-12-7-8-16(19)14(9-12)18(25)26/h2-9H,10H2,1H3,(H,25,26) AVPQBTDFOVKKJX-UHFFFAOYSA-N 49680 2-chloranyl-5-[2-[(5-chloranyl-3-methyl-1-phenyl-pyrazol-4-yl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[(N''E)-N''-[(5-chloro-3-methyl-1-phenyl-pyrazol-4-yl)methylene]hydrazino]benzoic acid::2-chloro-5-[(N'E)-N'-[(5-chloro-3-methyl-1-phenyl-pyrazol-4-yl)methylene]hydrazino]benzoic acid::2-chloro-5-[2-[(5-chloro-3-methyl-1-phenyl-4-pyrazolyl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[2-[(5-chloro-3-methyl-1-phenylpyrazol-4-yl)methylidene]hydrazinyl]benzoic acid::2-chloro-5-[N'-[(5-chloro-3-methyl-1-phenyl-pyrazol-4-yl)methylene]hydrazino]benzoic acid::MLS000417411::SMR000242629::cid_4321955 Oxysterols receptor LXR-beta 67518 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49680&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91896831 252629955 ZINC13138521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238966 Oc1ccc(cc1)N=Nc1ccc2ccccc2c1 InChI=1S/C16H12N2O/c19-16-9-7-14(8-10-16)17-18-15-6-5-12-3-1-2-4-13(12)11-15/h1-11,19H SDOPORHPKVAKOO-UHFFFAOYSA-N 115048 4-(2-naphthalenylhydrazinylidene)-1-cyclohexa-2,5-dienone::4-(2-naphthyldiazenyl)phenol::4-(2-naphthylhydrazono)cyclohexa-2,5-dien-1-one::4-(naphthalen-2-ylhydrazinylidene)cyclohexa-2,5-dien-1-one::MLS001180999::SMR000477767::cid_7099036 Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115048&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7099036 252664506 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 238974 Cc1ccc(cc1C)-c1nc(no1)-c1ccncc1 InChI=1S/C15H13N3O/c1-10-3-4-13(9-11(10)2)15-17-14(18-19-15)12-5-7-16-8-6-12/h3-9H,1-2H3 OVRLQALANUTFEM-UHFFFAOYSA-N 115055 4-[5-(3,4-Dimethyl-phenyl)-[1,2,4]oxadiazol-3-yl]-pyridine::5-(3,4-dimethylphenyl)-3-(4-pyridyl)-1,2,4-oxadiazole::5-(3,4-dimethylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole::MLS001205218::SMR000523591::cid_888298 Oxysterols receptor LXR-beta 67526 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115055&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 888298 252664513 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239043 CC(=Nc1ccc(Cl)cc1N)c1c(O)cc(C)oc1=O InChI=1S/C14H13ClN2O3/c1-7-5-12(18)13(14(19)20-7)8(2)17-11-4-3-9(15)6-10(11)16/h3-6,18H,16H2,1-2H3 IXSQQLXHDWOVBS-UHFFFAOYSA-N 115105 (3Z)-3-[1-(2-amino-4-chloro-anilino)ethylidene]-6-methyl-pyran-2,4-quinone::(3Z)-3-[1-(2-amino-4-chloroanilino)ethylidene]-6-methylpyran-2,4-dione::(3Z)-3-[1-[(2-azanyl-4-chloranyl-phenyl)amino]ethylidene]-6-methyl-pyran-2,4-dione::MLS003171254::SMR001875158::cid_5948348 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115105&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5948348 252664561 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239050 COC(=O)[C@@]12CCCCC=C1N(CC=C)C(=O)[C@H]2CC(=O)N1CCSCC1 InChI=1S/C20H28N2O4S/c1-3-9-22-16-7-5-4-6-8-20(16,19(25)26-2)15(18(22)24)14-17(23)21-10-12-27-13-11-21/h3,7,15H,1,4-6,8-14H2,2H3/t15-,20-/m1/s1 YNXKXWXNLSKNND-FOIQADDNSA-N 115112 (3S,3aR)-1-allyl-2-keto-3-(2-keto-2-thiomorpholino-ethyl)-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylic acid methyl ester::(3S,3aR)-2-oxo-3-(2-oxo-2-thiomorpholin-4-ylethyl)-1-prop-2-enyl-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylic acid methyl ester::MLS004259454::SMR003089419::cid_60158113::methyl (3S,3aR)-2-oxidanylidene-3-(2-oxidanylidene-2-thiomorpholin-4-yl-ethyl)-1-prop-2-enyl-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylate::methyl (3S,3aR)-2-oxo-3-(2-oxo-2-thiomorpholin-4-ylethyl)-1-prop-2-enyl-4,5,6,7-tetrahydro-3H-cyclohepta[b]pyrrole-3a-carboxylate Oxysterols receptor LXR-beta 67535 PubChem 10.7270/Q2ZP44SP aid743052 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=115112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=115112&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 60158113 252664568 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239122 Cc1csc(NC(=O)c2cc(nc3ccccc23)-c2ccco2)n1 InChI=1S/C18H13N3O2S/c1-11-10-24-18(19-11)21-17(22)13-9-15(16-7-4-8-23-16)20-14-6-3-2-5-12(13)14/h2-10H,1H3,(H,19,21,22) FJNSTSOBVHFVEK-UHFFFAOYSA-N 50280 2-(2-furanyl)-N-(4-methyl-2-thiazolyl)-4-quinolinecarboxamide::2-(2-furyl)-N-(4-methylthiazol-2-yl)cinchoninamide::2-(furan-2-yl)-N-(4-methyl-1,3-thiazol-2-yl)quinoline-4-carboxamide::MLS000391583::SMR000260618::cid_2366866 Oxysterols receptor LXR-beta 67547 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 2366866 252630546 ZINC02636208 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239130 O=C(\C=C\c1cccs1)N1CCc2ccccc12 InChI=1S/C15H13NOS/c17-15(8-7-13-5-3-11-18-13)16-10-9-12-4-1-2-6-14(12)16/h1-8,11H,9-10H2/b8-7+ AGFMCRQYCDIVNO-BQYQJAHWSA-N 49636 (E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-2-propen-1-one::(E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-yl-prop-2-en-1-one::(E)-1-(2,3-dihydroindol-1-yl)-3-thiophen-2-ylprop-2-en-1-one::(E)-1-indolin-1-yl-3-(2-thienyl)prop-2-en-1-one::1-[3-(2-thienyl)acryloyl]indoline::MLS000678854::SMR000269910::cid_885474 Oxysterols receptor LXR-beta 67533 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=49636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=49636&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 885474 252629911 ZINC00457757 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239198 CN1c2ccsc2C(NNc2ccc(F)cc2)=CS1(=O)=O InChI=1S/C13H12FN3O2S2/c1-17-12-6-7-20-13(12)11(8-21(17,18)19)16-15-10-4-2-9(14)3-5-10/h2-8,15-16H,1H3 APCFAYGCJVRTNL-UHFFFAOYSA-N 114905 1-methyl-2lambda~6~-thieno[3,2-c][1,2]thiazine-2,2,4(1H,3H)-trione 4-[N-(4-fluorophenyl)hydrazone]::4-fluoranyl-N-[(E)-[1-methyl-2,2-bis(oxidanylidene)thieno[3,2-c][1,2]thiazin-4-ylidene]amino]aniline::4-fluoro-N-[(E)-(1-methyl-2,2-dioxo-4-thieno[3,2-c]thiazinylidene)amino]aniline::4-fluoro-N-[(E)-(1-methyl-2,2-dioxothieno[3,2-c]thiazin-4-ylidene)amino]aniline::MLS000755269::SMR000338138::[(E)-(2,2-diketo-1-methyl-thieno[3,2-c]thiazin-4-ylidene)amino]-(4-fluorophenyl)amine::cid_5927210 Oxysterols receptor LXR-beta 67513 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114905&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91899742 252664368 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239205 OC(=O)c1ccc(CN=Nc2ccc(cn2)C(F)(F)F)cc1 InChI=1S/C14H10F3N3O2/c15-14(16,17)11-5-6-12(18-8-11)20-19-7-9-1-3-10(4-2-9)13(21)22/h1-6,8H,7H2,(H,21,22) FMUXCTIVWZQNHR-UHFFFAOYSA-N 69367 4-[(E)-[[5-(trifluoromethyl)-2-pyridyl]hydrazono]methyl]benzoic acid::4-[[[5-(trifluoromethyl)-2-pyridinyl]hydrazinylidene]methyl]benzoic acid::4-[[[5-(trifluoromethyl)-2-pyridyl]hydrazono]methyl]benzoic acid::4-[[[5-(trifluoromethyl)pyridin-2-yl]hydrazinylidene]methyl]benzoic acid::MLS000775567::SMR000370441::cid_4840449 Oxysterols receptor LXR-beta 67574 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69367&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91897825 252647535 ZINC33497029 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239274 Cc1c(oc2cc(C)c(C)cc12)C(=O)NCC(N1CCCC1)c1ccco1 InChI=1S/C22H26N2O3/c1-14-11-17-16(3)21(27-20(17)12-15(14)2)22(25)23-13-18(19-7-6-10-26-19)24-8-4-5-9-24/h6-7,10-12,18H,4-5,8-9,13H2,1-3H3,(H,23,25) ZEBKKIOLKCHHJO-UHFFFAOYSA-N 114947 MLS001157951::N-[2-(2-furanyl)-2-(1-pyrrolidinyl)ethyl]-3,5,6-trimethyl-2-benzofurancarboxamide::N-[2-(2-furyl)-2-pyrrolidino-ethyl]-3,5,6-trimethyl-coumarilamide::N-[2-(furan-2-yl)-2-pyrrolidin-1-yl-ethyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide::N-[2-(furan-2-yl)-2-pyrrolidin-1-ylethyl]-3,5,6-trimethyl-1-benzofuran-2-carboxamide::SMR000651416::cid_16445678 Oxysterols receptor LXR-beta 67595 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114947&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16445678 252664409 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 239281 Cc1c(oc2ccccc12)C(=O)Nc1nccs1 InChI=1S/C13H10N2O2S/c1-8-9-4-2-3-5-10(9)17-11(8)12(16)15-13-14-6-7-18-13/h2-7H,1H3,(H,14,15,16) RDJWFCYOWJFLNV-UHFFFAOYSA-N 114954 3-methyl-N-(1,3-thiazol-2-yl)-1-benzofuran-2-carboxamide::3-methyl-N-(2-thiazolyl)-2-benzofurancarboxamide::3-methyl-N-thiazol-2-yl-coumarilamide::MLS001077610::SMR000715153::cid_4750125 Oxysterols receptor LXR-beta 67608 PubChem 10.7270/Q2TX3D2C aid720737 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114954&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4750125 252664416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519372 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H20F3N5O2S/c1-12(2)18-17-13(10-27(18)19-24-8-7-16(25-19)20(21,22)23)11-28(26-17)14-5-4-6-15(9-14)31(3,29)30/h4-9,11-12,18H,10H2,1-3H3/t18-/m1/s1 WZQNVHXAZPMTQI-GOSISDBHSA-N 50192762 CHEMBL3959681 Oxysterols receptor LXR-beta 28 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192762&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134154676 375075941 CHEMBL3959681 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519373 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1ccnc(n1)C(F)(F)F InChI=1S/C20H20F3N5O2S/c1-12(2)18-17-13(10-27(18)16-7-8-24-19(25-16)20(21,22)23)11-28(26-17)14-5-4-6-15(9-14)31(3,29)30/h4-9,11-12,18H,10H2,1-3H3/t18-/m1/s1 DYLLPHYLYLHOKV-GOSISDBHSA-N 50192763 CHEMBL3933543 Oxysterols receptor LXR-beta 109 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192763&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134138904 375075942 CHEMBL3933543 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519374 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1cc(nc(C)n1)C(F)(F)F InChI=1S/C21H22F3N5O2S/c1-12(2)20-19-14(10-28(20)18-9-17(21(22,23)24)25-13(3)26-18)11-29(27-19)15-6-5-7-16(8-15)32(4,30)31/h5-9,11-12,20H,10H2,1-4H3/t20-/m1/s1 IGGSXCWSHVYVMA-HXUWFJFHSA-N 50192753 CHEMBL3985591 Oxysterols receptor LXR-beta 18 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search TAC 2HCJ,2UXO,3Q5P,1I97,5J5B,2HDN,5J7L,6FPL,6FPM,2VKE,2TRT,1HNW,4B3A,4V9A 134157776 104075582 CHEMBL3985591 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519375 COc1cc(cc(C)n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C22H26N4O3S/c1-14(2)22-21-16(12-25(22)18-9-15(3)23-20(11-18)29-4)13-26(24-21)17-7-6-8-19(10-17)30(5,27)28/h6-11,13-14,22H,12H2,1-5H3/t22-/m1/s1 LNVWYDLYTZAVJQ-JOCHJYFZSA-N 50192758 CHEMBL3976470 Oxysterols receptor LXR-beta 22 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192758&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134151855 375075937 CHEMBL3976470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519386 COc1nc(C)cc(n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C21H25N5O3S/c1-13(2)20-19-15(11-25(20)18-9-14(3)22-21(23-18)29-4)12-26(24-19)16-7-6-8-17(10-16)30(5,27)28/h6-10,12-13,20H,11H2,1-5H3/t20-/m1/s1 VRLNYADEEBSDKC-HXUWFJFHSA-N 50192755 CHEMBL3956923 Oxysterols receptor LXR-beta 17 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134155310 375075934 CHEMBL3956923 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519388 COc1cc(ccn1)N1Cc2cn(nc2[C@H]1C(C)(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C22H26N4O3S/c1-22(2,3)21-20-15(13-25(21)16-9-10-23-19(12-16)29-4)14-26(24-20)17-7-6-8-18(11-17)30(5,27)28/h6-12,14,21H,13H2,1-5H3/t21-/m0/s1 XOPXTKOQXWMGEF-NRFANRHFSA-N 50192750 CHEMBL3940521 Oxysterols receptor LXR-beta 38 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134145788 375075930 CHEMBL3940521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519390 COc1nc(C)cc(n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C21H25N5O3S/c1-13(2)20-19-15(11-25(20)18-9-14(3)22-21(23-18)29-4)12-26(24-19)16-7-6-8-17(10-16)30(5,27)28/h6-10,12-13,20H,11H2,1-5H3/t20-/m1/s1 VRLNYADEEBSDKC-HXUWFJFHSA-N 50192755 CHEMBL3956923 Oxysterols receptor LXR-beta 16 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134155310 375075934 CHEMBL3956923 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519392 COc1cc(nc(C)n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C21H25N5O3S/c1-13(2)21-20-15(11-25(21)18-10-19(29-4)23-14(3)22-18)12-26(24-20)16-7-6-8-17(9-16)30(5,27)28/h6-10,12-13,21H,11H2,1-5H3/t21-/m1/s1 VSLBVBOGQLFVOY-OAQYLSRUSA-N 50192757 CHEMBL3914727 Oxysterols receptor LXR-beta 18 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192757&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134142943 375075936 CHEMBL3914727 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519400 COc1ncnc(N2Cc3cn(nc3[C@H]2C(C)C)-c2cccc(c2)S(C)(=O)=O)c1F InChI=1S/C20H22FN5O3S/c1-12(2)18-17-13(9-25(18)19-16(21)20(29-3)23-11-22-19)10-26(24-17)14-6-5-7-15(8-14)30(4,27)28/h5-8,10-12,18H,9H2,1-4H3/t18-/m1/s1 XOTHLYNSDMSVGX-GOSISDBHSA-N 50192752 CHEMBL3905741 Oxysterols receptor LXR-beta 1.000000 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134135247 375075932 CHEMBL3905741 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519402 COc1ncc(F)c(n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C20H22FN5O3S/c1-12(2)18-17-13(10-25(18)19-16(21)9-22-20(23-19)29-3)11-26(24-17)14-6-5-7-15(8-14)30(4,27)28/h5-9,11-12,18H,10H2,1-4H3/t18-/m1/s1 HDDKTNCZLILPNB-GOSISDBHSA-N 50192760 CHEMBL3972392 Oxysterols receptor LXR-beta 15 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6Y8 5KYJ 121596967 375075939 CHEMBL3972392 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519404 COc1cc(ccn1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C21H24N4O3S/c1-14(2)21-20-15(12-24(21)16-8-9-22-19(11-16)28-3)13-25(23-20)17-6-5-7-18(10-17)29(4,26)27/h5-11,13-14,21H,12H2,1-4H3/t21-/m1/s1 LYZQPKJAYGTLJX-OAQYLSRUSA-N 50192754 CHEMBL3913348 Oxysterols receptor LXR-beta 13 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134142736 375075933 CHEMBL3913348 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519409 CC(C)C1N(Cc2cn(nc12)-c1ccc(CO)c(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C22H24F3N5O4S/c1-12(2)19-18-15(8-29(19)21-26-7-14(11-32)20(27-21)22(23,24)25)9-30(28-18)16-5-4-13(10-31)17(6-16)35(3,33)34/h4-7,9,12,19,31-32H,8,10-11H2,1-3H3 HFGCUOYYZKNQLX-UHFFFAOYSA-N 50192751 CHEMBL3889601 Oxysterols receptor LXR-beta 26 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134131424 375075931 CHEMBL3889601 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519410 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1cc(ncn1)C(F)(F)F InChI=1S/C20H20F3N5O2S/c1-12(2)19-18-13(9-27(19)17-8-16(20(21,22)23)24-11-25-17)10-28(26-18)14-5-4-6-15(7-14)31(3,29)30/h4-8,10-12,19H,9H2,1-3H3/t19-/m1/s1 OMMCNHJJHLQJHQ-LJQANCHMSA-N 50192759 CHEMBL3960195 Oxysterols receptor LXR-beta 7.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134154775 375075938 CHEMBL3960195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519414 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m0/s1 FPVIRRAMNBCEDK-KRWDZBQOSA-N 50177015 CHEMBL3814206::US10144715, Compound 19-1 Oxysterols receptor LXR-beta 21 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 67S 5I4V 91827457 346549211 CHEMBL3814206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519415 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C21H22F3N5O3S/c1-12(2)18-17-14(10-29(27-17)15-5-4-6-16(7-15)33(3,31)32)9-28(18)20-25-8-13(11-30)19(26-20)21(22,23)24/h4-8,10,12,18,30H,9,11H2,1-3H3/t18-/m1/s1 NCZXBZJVJRJUSC-GOSISDBHSA-N 50192756 CHEMBL3932169 Oxysterols receptor LXR-beta 46 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6Y4 5KYA 121596966 375075935 CHEMBL3932169 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519416 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1cc(ncn1)C(F)(F)F InChI=1S/C20H20F3N5O2S/c1-12(2)19-18-13(9-27(19)17-8-16(20(21,22)23)24-11-25-17)10-28(26-18)14-5-4-6-15(7-14)31(3,29)30/h4-8,10-12,19H,9H2,1-3H3/t19-/m1/s1 OMMCNHJJHLQJHQ-LJQANCHMSA-N 50192759 CHEMBL3960195 Oxysterols receptor LXR-beta 35 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134154775 375075938 CHEMBL3960195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519417 COc1cc(ccn1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O InChI=1S/C21H24N4O3S/c1-14(2)21-20-15(12-24(21)16-8-9-22-19(11-16)28-3)13-25(23-20)17-6-5-7-18(10-17)29(4,26)27/h5-11,13-14,21H,12H2,1-4H3/t21-/m1/s1 LYZQPKJAYGTLJX-OAQYLSRUSA-N 50192754 CHEMBL3913348 Oxysterols receptor LXR-beta 45 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134142736 375075933 CHEMBL3913348 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519425 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H20F3N5O2S/c1-12(2)18-17-13(10-27(18)19-24-8-7-16(25-19)20(21,22)23)11-28(26-17)14-5-4-6-15(9-14)31(3,29)30/h4-9,11-12,18H,10H2,1-3H3/t18-/m1/s1 WZQNVHXAZPMTQI-GOSISDBHSA-N 50192762 CHEMBL3959681 Oxysterols receptor LXR-beta 7.0 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192762&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134154676 375075941 CHEMBL3959681 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50519430 CC(C)[C@H]1N(Cc2cn(nc12)-c1cccc(c1)S(C)(=O)=O)c1ccnc(n1)C(F)(F)F InChI=1S/C20H20F3N5O2S/c1-12(2)18-17-13(10-27(18)16-7-8-24-19(25-16)20(21,22)23)11-28(26-17)14-5-4-6-15(9-14)31(3,29)30/h4-9,11-12,18H,10H2,1-3H3/t18-/m1/s1 DYLLPHYLYLHOKV-GOSISDBHSA-N 50192763 CHEMBL3933543 Oxysterols receptor LXR-beta 13 ChEMBL 10.1016/j.bmcl.2016.08.089 10.7270/Q28P62GC 27599745 Tice, CM; Noto, PB; Fan, KY; Zhao, W; Lotesta, SD; Dong, C; Marcus, AP; Zheng, YJ; Chen, G; Wu, Z; Van Orden, R; Zhou, J; Bukhtiyarov, Y; Zhao, Y; Lipinski, K; Howard, L; Guo, J; Kandpal, G; Meng, S; Hardy, A; Krosky, P; Gregg, RE; Leftheris, K; McKeever, BM; Singh, SB; Lala, D; McGeehan, GM; Zhuang, L; Claremon, DA Vitae Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192763&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134138904 375075942 CHEMBL3933543 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51069961 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 103 ChEMBL 10.1016/j.bmcl.2013.05.030 10.7270/Q2NK3GF4 23769638 Jia, Y; Hoang, MH; Jun, HJ; Lee, JH; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51069962 Oc1cc2oc(c(O)cc2c(=[OH+])c1)-c1ccc(O)c(O)c1 InChI=1S/C15H10O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-6,16-17,19-20H/p+1 QFCUROSHGOWZEG-UHFFFAOYSA-O 50241503 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopyrylium::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenylium::3,3',4',5,7-pentahydroxyflavylium::3,5,7,3'',4''-Pentahydroxyflavylium::CHEMBL404515::CHEMBL511367::Cyanidin::cyanidin(1+) Oxysterols receptor LXR-beta 125200 ChEMBL 10.1016/j.bmcl.2013.05.030 10.7270/Q2NK3GF4 23769638 Jia, Y; Hoang, MH; Jun, HJ; Lee, JH; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241503&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 128861 104098794 27843 CHEMBL511367CHEMBL404515 ZINC03775158 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51069966 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 103 ChEMBL 10.1016/j.bmcl.2013.05.030 10.7270/Q2NK3GF4 23769638 Jia, Y; Hoang, MH; Jun, HJ; Lee, JH; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51069967 Oc1cc2oc(c(O)cc2c(=[OH+])c1)-c1ccc(O)c(O)c1 InChI=1S/C15H10O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-6,16-17,19-20H/p+1 QFCUROSHGOWZEG-UHFFFAOYSA-O 50241503 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopyrylium::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromenylium::3,3',4',5,7-pentahydroxyflavylium::3,5,7,3'',4''-Pentahydroxyflavylium::CHEMBL404515::CHEMBL511367::Cyanidin::cyanidin(1+) Oxysterols receptor LXR-beta 73200 ChEMBL 10.1016/j.bmcl.2013.05.030 10.7270/Q2NK3GF4 23769638 Jia, Y; Hoang, MH; Jun, HJ; Lee, JH; Lee, SJ Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241503&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 128861 104098794 27843 CHEMBL511367CHEMBL404515 ZINC03775158 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531218 CC(C)(O)c1cn(c(n1)C(C)(C)c1cccc(F)c1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29ClF2N2O4S/c1-28(2,21-7-6-8-22(31)26(21)30)27-33-25(29(3,4)36)15-34(27)19-11-9-17(10-12-19)18-13-23(32)20(16-35)24(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 IQFPWMNABYUYJC-UHFFFAOYSA-N 50204071 CHEMBL3953927 Oxysterols receptor LXR-beta 72 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822225 375980323 CHEMBL3953927 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531219 CC(C)(O)c1cn(c(n1)C(C)(C)c1cccc(F)c1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29ClF2N2O4S/c1-28(2,21-7-6-8-22(31)26(21)30)27-33-25(29(3,4)36)15-34(27)19-11-9-17(10-12-19)18-13-23(32)20(16-35)24(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 IQFPWMNABYUYJC-UHFFFAOYSA-N 50204071 CHEMBL3953927 Oxysterols receptor LXR-beta 76 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822225 375980323 CHEMBL3953927 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531222 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(F)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28ClF3N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 ZXGHHBLRYXFVLD-UHFFFAOYSA-N 50204073 CHEMBL3917300 Oxysterols receptor LXR-beta 1.000000 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822226 375980325 CHEMBL3917300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531224 CC(C)(O)c1cn(c(Cc2c(Cl)cccc2Cl)n1)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C27H25Cl2FN2O4S/c1-27(2,34)25-14-32(26(31-25)13-19-21(28)5-4-6-22(19)29)18-9-7-16(8-10-18)17-11-23(30)20(15-33)24(12-17)37(3,35)36/h4-12,14,33-34H,13,15H2,1-3H3 YIPWZEZDOVPNDU-UHFFFAOYSA-N 50204075 CHEMBL3980683 Oxysterols receptor LXR-beta 140 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822066 375980327 CHEMBL3980683 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531225 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H28Cl2N2O3S/c1-27(2,25-22(29)10-7-11-23(25)30)26-31-24(28(3,4)33)17-32(26)20-14-12-18(13-15-20)19-8-6-9-21(16-19)36(5,34)35/h6-17,33H,1-5H3 QTHAGUHHLRNGTA-UHFFFAOYSA-N 50204076 CHEMBL3890276 Oxysterols receptor LXR-beta 18 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951324 375980328 CHEMBL3890276 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531226 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H30ClFN2O4S/c1-28(2,22-8-6-7-9-23(22)30)27-32-26(29(3,4)35)16-33(27)20-12-10-18(11-13-20)19-14-24(31)21(17-34)25(15-19)38(5,36)37/h6-16,34-35H,17H2,1-5H3 WUVSLEJBHNUDBB-UHFFFAOYSA-N 50204077 CHEMBL3944154 Oxysterols receptor LXR-beta 72 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134146533 375980329 CHEMBL3944154 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531227 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3 JLPURTXCSILYLW-UHFFFAOYSA-N 50034775 CHEMBL3360975::US10543183, Compound 38::US10945978, Compound 38 Oxysterols receptor LXR-beta 250 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652 4RAK 59251511 313066503 CHEMBL3360975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531229 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H30ClFN2O4S/c1-28(2,22-8-6-7-9-23(22)30)27-32-26(29(3,4)35)16-33(27)20-12-10-18(11-13-20)19-14-24(31)21(17-34)25(15-19)38(5,36)37/h6-16,34-35H,17H2,1-5H3 WUVSLEJBHNUDBB-UHFFFAOYSA-N 50204077 CHEMBL3944154 Oxysterols receptor LXR-beta 8.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134146533 375980329 CHEMBL3944154 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531230 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H28Cl2N2O3S/c1-27(2,25-22(29)10-7-11-23(25)30)26-31-24(28(3,4)33)17-32(26)20-14-12-18(13-15-20)19-8-6-9-21(16-19)36(5,34)35/h6-17,33H,1-5H3 QTHAGUHHLRNGTA-UHFFFAOYSA-N 50204076 CHEMBL3890276 Oxysterols receptor LXR-beta 380 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951324 375980328 CHEMBL3890276 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531231 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29ClF2N2O4S/c1-28(2,20-8-6-7-9-21(20)30)27-33-26(29(3,4)36)15-34(27)24-11-10-17(12-23(24)32)18-13-22(31)19(16-35)25(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 GUQJFTLEMOZJBL-UHFFFAOYSA-N 50204078 CHEMBL3926292 Oxysterols receptor LXR-beta 46 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822147 375980330 CHEMBL3926292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531533 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C29H31ClN2O4S/c1-28(2,23-8-6-7-9-24(23)30)27-31-26(29(3,4)34)17-32(27)22-14-12-19(13-15-22)20-10-11-21(18-33)25(16-20)37(5,35)36/h6-17,33-34H,18H2,1-5H3 NBADHEUMPIIURD-UHFFFAOYSA-N 50204081 CHEMBL3913162 Oxysterols receptor LXR-beta 170 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134142531 375980333 CHEMBL3913162 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531534 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29Cl2FN2O4S/c1-28(2,26-21(30)7-6-8-22(26)31)27-33-25(29(3,4)36)15-34(27)19-11-9-17(10-12-19)18-13-23(32)20(16-35)24(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 LODWYHGIAQYCAL-UHFFFAOYSA-N 50204079 CHEMBL3935187 Oxysterols receptor LXR-beta 3.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822148 375980331 CHEMBL3935187 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531535 CC(C)(O)c1cn(c(Cc2c(Cl)cccc2Cl)n1)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C27H25Cl2FN2O4S/c1-27(2,34)25-14-32(26(31-25)13-19-21(28)5-4-6-22(19)29)18-9-7-16(8-10-18)17-11-23(30)20(15-33)24(12-17)37(3,35)36/h4-12,14,33-34H,13,15H2,1-3H3 YIPWZEZDOVPNDU-UHFFFAOYSA-N 50204075 CHEMBL3980683 Oxysterols receptor LXR-beta 42 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822066 375980327 CHEMBL3980683 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531536 CC(C)(O)c1cn(c(Cc2c(Cl)cccc2Cl)n1)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C27H25Cl2FN2O4S/c1-27(2,34)25-14-32(26(31-25)13-19-21(28)5-4-6-22(19)29)18-9-7-16(8-10-18)17-11-23(30)20(15-33)24(12-17)37(3,35)36/h4-12,14,33-34H,13,15H2,1-3H3 YIPWZEZDOVPNDU-UHFFFAOYSA-N 50204075 CHEMBL3980683 Oxysterols receptor LXR-beta 5.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822066 375980327 CHEMBL3980683 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531538 CC(c1nc(cn1-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O)C(C)(C)O)c1c(Cl)cccc1Cl InChI=1S/C28H26Cl2F2N2O4S/c1-15(26-19(29)6-5-7-20(26)30)27-33-25(28(2,3)36)13-34(27)23-9-8-16(10-22(23)32)17-11-21(31)18(14-35)24(12-17)39(4,37)38/h5-13,15,35-36H,14H2,1-4H3 OSCBEESEHIRILI-UHFFFAOYSA-N 50204082 CHEMBL3945820 Oxysterols receptor LXR-beta 25 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822063 375980334 CHEMBL3945820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531540 CC(c1nc(cn1-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O)C(C)(C)O)c1c(Cl)cccc1Cl InChI=1S/C28H26Cl2F2N2O4S/c1-15(26-19(29)6-5-7-20(26)30)27-33-25(28(2,3)36)13-34(27)23-9-8-16(10-22(23)32)17-11-21(31)18(14-35)24(12-17)39(4,37)38/h5-13,15,35-36H,14H2,1-4H3 OSCBEESEHIRILI-UHFFFAOYSA-N 50204082 CHEMBL3945820 Oxysterols receptor LXR-beta 2.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822063 375980334 CHEMBL3945820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531543 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29Cl2FN2O4S/c1-28(2,26-21(30)7-6-8-22(26)31)27-33-25(29(3,4)36)15-34(27)19-11-9-17(10-12-19)18-13-23(32)20(16-35)24(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 LODWYHGIAQYCAL-UHFFFAOYSA-N 50204079 CHEMBL3935187 Oxysterols receptor LXR-beta 42 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822148 375980331 CHEMBL3935187 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531544 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29ClF2N2O4S/c1-28(2,20-8-6-7-9-21(20)30)27-33-26(29(3,4)36)15-34(27)24-11-10-17(12-23(24)32)18-13-22(31)19(16-35)25(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 GUQJFTLEMOZJBL-UHFFFAOYSA-N 50204078 CHEMBL3926292 Oxysterols receptor LXR-beta 2.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822147 375980330 CHEMBL3926292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531548 CC(O)c1ccc(cc1S(C)(=O)=O)-c1ccc(cc1)-n1cc(nc1C(C)(C)c1ccccc1Cl)C(C)(C)O InChI=1S/C30H33ClN2O4S/c1-19(34)23-16-13-21(17-26(23)38(6,36)37)20-11-14-22(15-12-20)33-18-27(30(4,5)35)32-28(33)29(2,3)24-9-7-8-10-25(24)31/h7-19,34-35H,1-6H3 KDKLTCKHENMCSN-UHFFFAOYSA-N 50204080 CHEMBL3963566 Oxysterols receptor LXR-beta 220 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134150059 375980332 CHEMBL3963566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 859982 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 40.0 US Patent 10.7270/Q2JW8H8C aid1804094 US10543183 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531549 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H28Cl2N2O3S/c1-27(2,25-22(29)10-7-11-23(25)30)26-31-24(28(3,4)33)17-32(26)20-14-12-18(13-15-20)19-8-6-9-21(16-19)36(5,34)35/h6-17,33H,1-5H3 QTHAGUHHLRNGTA-UHFFFAOYSA-N 50204076 CHEMBL3890276 Oxysterols receptor LXR-beta 170 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951324 375980328 CHEMBL3890276 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531555 CC(C)(O)c1cn(c(Cc2ccccc2Cl)n1)-c1ccc(cc1)-c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C27H27ClN2O4S/c1-27(2,32)25-16-30(26(29-25)15-20-6-4-5-7-23(20)28)22-12-10-18(11-13-22)19-8-9-21(17-31)24(14-19)35(3,33)34/h4-14,16,31-32H,15,17H2,1-3H3 VVVMBZVHNIYCQS-UHFFFAOYSA-N 50204085 CHEMBL3960606 Oxysterols receptor LXR-beta 300 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204085&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251574 375980336 CHEMBL3960606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531556 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C29H31ClN2O4S/c1-28(2,23-8-6-7-9-24(23)30)27-31-26(29(3,4)34)17-32(27)22-14-12-19(13-15-22)20-10-11-21(18-33)25(16-20)37(5,35)36/h6-17,33-34H,18H2,1-5H3 NBADHEUMPIIURD-UHFFFAOYSA-N 50204081 CHEMBL3913162 Oxysterols receptor LXR-beta 300 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134142531 375980333 CHEMBL3913162 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531559 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1F)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H30F2N2O4S/c1-28(2,22-8-6-7-9-23(22)30)27-32-26(29(3,4)35)16-33(27)20-12-10-18(11-13-20)19-14-24(31)21(17-34)25(15-19)38(5,36)37/h6-16,34-35H,17H2,1-5H3 PABVYBCMEDLXBK-UHFFFAOYSA-N 50204083 CHEMBL3941775 Oxysterols receptor LXR-beta 43 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49821979 375980335 CHEMBL3941775 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531561 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29Cl2FN2O4S/c1-28(2,26-21(30)7-6-8-22(26)31)27-33-25(29(3,4)36)15-34(27)19-11-9-17(10-12-19)18-13-23(32)20(16-35)24(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 LODWYHGIAQYCAL-UHFFFAOYSA-N 50204079 CHEMBL3935187 Oxysterols receptor LXR-beta 15 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822148 375980331 CHEMBL3935187 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531563 CC(C)(O)c1cn(c(n1)C(C)(C)c1cccc(F)c1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29ClF2N2O4S/c1-28(2,21-7-6-8-22(31)26(21)30)27-33-25(29(3,4)36)15-34(27)19-11-9-17(10-12-19)18-13-23(32)20(16-35)24(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 IQFPWMNABYUYJC-UHFFFAOYSA-N 50204071 CHEMBL3953927 Oxysterols receptor LXR-beta 8.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204071&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822225 375980323 CHEMBL3953927 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531568 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 HNAJDMYOTDNOBK-UHFFFAOYSA-N 50204072 CHEMBL3945199::US10543183, Compound 12::US10945978, Compound 12 Oxysterols receptor LXR-beta 24 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6OX 5JY3 49787490 375980324 CHEMBL3945199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531570 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(F)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28ClF3N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 ZXGHHBLRYXFVLD-UHFFFAOYSA-N 50204073 CHEMBL3917300 Oxysterols receptor LXR-beta 20 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822226 375980325 CHEMBL3917300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531573 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1Cl)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl3FN2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-21(23)32)17-12-22(33)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 PCAWBEDTJCPNOG-UHFFFAOYSA-N 50204074 CHEMBL3910597 Oxysterols receptor LXR-beta 5.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49821981 375980326 CHEMBL3910597 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531576 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 HNAJDMYOTDNOBK-UHFFFAOYSA-N 50204072 CHEMBL3945199::US10543183, Compound 12::US10945978, Compound 12 Oxysterols receptor LXR-beta 0.600000 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6OX 5JY3 49787490 375980324 CHEMBL3945199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531579 CC(O)c1ccc(cc1S(C)(=O)=O)-c1ccc(cc1)-n1cc(nc1C(C)(C)c1ccccc1Cl)C(C)(C)O InChI=1S/C30H33ClN2O4S/c1-19(34)23-16-13-21(17-26(23)38(6,36)37)20-11-14-22(15-12-20)33-18-27(30(4,5)35)32-28(33)29(2,3)24-9-7-8-10-25(24)31/h7-19,34-35H,1-6H3 KDKLTCKHENMCSN-UHFFFAOYSA-N 50204080 CHEMBL3963566 Oxysterols receptor LXR-beta 21 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134150059 375980332 CHEMBL3963566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531580 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 HNAJDMYOTDNOBK-UHFFFAOYSA-N 50204072 CHEMBL3945199::US10543183, Compound 12::US10945978, Compound 12 Oxysterols receptor LXR-beta 10.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6OX 5JY3 49787490 375980324 CHEMBL3945199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531581 CC(O)c1ccc(cc1S(C)(=O)=O)-c1ccc(cc1)-n1cc(nc1C(C)(C)c1ccccc1Cl)C(C)(C)O InChI=1S/C30H33ClN2O4S/c1-19(34)23-16-13-21(17-26(23)38(6,36)37)20-11-14-22(15-12-20)33-18-27(30(4,5)35)32-28(33)29(2,3)24-9-7-8-10-25(24)31/h7-19,34-35H,1-6H3 KDKLTCKHENMCSN-UHFFFAOYSA-N 50204080 CHEMBL3963566 Oxysterols receptor LXR-beta 870 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134150059 375980332 CHEMBL3963566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531585 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C29H31ClN2O4S/c1-28(2,23-8-6-7-9-24(23)30)27-31-26(29(3,4)34)17-32(27)22-14-12-19(13-15-22)20-10-11-21(18-33)25(16-20)37(5,35)36/h6-17,33-34H,18H2,1-5H3 NBADHEUMPIIURD-UHFFFAOYSA-N 50204081 CHEMBL3913162 Oxysterols receptor LXR-beta 12 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204081&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134142531 375980333 CHEMBL3913162 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531586 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3 JLPURTXCSILYLW-UHFFFAOYSA-N 50034775 CHEMBL3360975::US10543183, Compound 38::US10945978, Compound 38 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652 4RAK 59251511 313066503 CHEMBL3360975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531588 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3 JLPURTXCSILYLW-UHFFFAOYSA-N 50034775 CHEMBL3360975::US10543183, Compound 38::US10945978, Compound 38 Oxysterols receptor LXR-beta 33 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652 4RAK 59251511 313066503 CHEMBL3360975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531589 CC(C)(O)c1cn(c(Cc2ccccc2Cl)n1)-c1ccc(cc1)-c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C27H27ClN2O4S/c1-27(2,32)25-16-30(26(29-25)15-20-6-4-5-7-23(20)28)22-12-10-18(11-13-22)19-8-9-21(17-31)24(14-19)35(3,33)34/h4-14,16,31-32H,15,17H2,1-3H3 VVVMBZVHNIYCQS-UHFFFAOYSA-N 50204085 CHEMBL3960606 Oxysterols receptor LXR-beta 60 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204085&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251574 375980336 CHEMBL3960606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531593 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H30ClFN2O4S/c1-28(2,22-8-6-7-9-23(22)30)27-32-26(29(3,4)35)16-33(27)20-12-10-18(11-13-20)19-14-24(31)21(17-34)25(15-19)38(5,36)37/h6-16,34-35H,17H2,1-5H3 WUVSLEJBHNUDBB-UHFFFAOYSA-N 50204077 CHEMBL3944154 Oxysterols receptor LXR-beta 57 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134146533 375980329 CHEMBL3944154 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531594 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1F)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H30F2N2O4S/c1-28(2,22-8-6-7-9-23(22)30)27-32-26(29(3,4)35)16-33(27)20-12-10-18(11-13-20)19-14-24(31)21(17-34)25(15-19)38(5,36)37/h6-16,34-35H,17H2,1-5H3 PABVYBCMEDLXBK-UHFFFAOYSA-N 50204083 CHEMBL3941775 Oxysterols receptor LXR-beta 160 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49821979 375980335 CHEMBL3941775 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531595 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1F)-c1ccc(cc1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H30F2N2O4S/c1-28(2,22-8-6-7-9-23(22)30)27-32-26(29(3,4)35)16-33(27)20-12-10-18(11-13-20)19-14-24(31)21(17-34)25(15-19)38(5,36)37/h6-16,34-35H,17H2,1-5H3 PABVYBCMEDLXBK-UHFFFAOYSA-N 50204083 CHEMBL3941775 Oxysterols receptor LXR-beta 12 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49821979 375980335 CHEMBL3941775 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531599 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 HNAJDMYOTDNOBK-UHFFFAOYSA-N 50204072 CHEMBL3945199::US10543183, Compound 12::US10945978, Compound 12 Oxysterols receptor LXR-beta 9.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6OX 5JY3 49787490 375980324 CHEMBL3945199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531600 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(F)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28ClF3N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 ZXGHHBLRYXFVLD-UHFFFAOYSA-N 50204073 CHEMBL3917300 Oxysterols receptor LXR-beta 41 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822226 375980325 CHEMBL3917300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531601 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1Cl)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl3FN2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-21(23)32)17-12-22(33)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 PCAWBEDTJCPNOG-UHFFFAOYSA-N 50204074 CHEMBL3910597 Oxysterols receptor LXR-beta 27 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49821981 375980326 CHEMBL3910597 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531602 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1Cl)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl3FN2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-21(23)32)17-12-22(33)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 PCAWBEDTJCPNOG-UHFFFAOYSA-N 50204074 CHEMBL3910597 Oxysterols receptor LXR-beta 2.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49821981 375980326 CHEMBL3910597 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531603 CC(C)(O)c1cn(c(Cc2ccccc2Cl)n1)-c1ccc(cc1)-c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C27H27ClN2O4S/c1-27(2,32)25-16-30(26(29-25)15-20-6-4-5-7-23(20)28)22-12-10-18(11-13-22)19-8-9-21(17-31)24(14-19)35(3,33)34/h4-14,16,31-32H,15,17H2,1-3H3 VVVMBZVHNIYCQS-UHFFFAOYSA-N 50204085 CHEMBL3960606 Oxysterols receptor LXR-beta 9.0 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204085&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59251574 375980336 CHEMBL3960606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531604 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3 JLPURTXCSILYLW-UHFFFAOYSA-N 50034775 CHEMBL3360975::US10543183, Compound 38::US10945978, Compound 38 Oxysterols receptor LXR-beta 1100 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652 4RAK 59251511 313066503 CHEMBL3360975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531606 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H29ClF2N2O4S/c1-28(2,20-8-6-7-9-21(20)30)27-33-26(29(3,4)36)15-34(27)24-11-10-17(12-23(24)32)18-13-22(31)19(16-35)25(14-18)39(5,37)38/h6-15,35-36H,16H2,1-5H3 GUQJFTLEMOZJBL-UHFFFAOYSA-N 50204078 CHEMBL3926292 Oxysterols receptor LXR-beta 50 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822147 375980330 CHEMBL3926292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50531608 CC(c1nc(cn1-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O)C(C)(C)O)c1c(Cl)cccc1Cl InChI=1S/C28H26Cl2F2N2O4S/c1-15(26-19(29)6-5-7-20(26)30)27-33-25(28(2,3)36)13-34(27)23-9-8-16(10-22(23)32)17-11-21(31)18(14-35)24(12-17)39(4,37)38/h5-13,15,35-36H,14H2,1-4H3 OSCBEESEHIRILI-UHFFFAOYSA-N 50204082 CHEMBL3945820 Oxysterols receptor LXR-beta 23 ChEMBL 10.1021/acsmedchemlett.6b00234 10.7270/Q2V98B13 27994765 Kick, EK; Busch, BB; Martin, R; Stevens, WC; Bollu, V; Xie, Y; Boren, BC; Nyman, MC; Nanao, MH; Nguyen, L; Plonowski, A; Schulman, IG; Yan, G; Zhang, H; Hou, X; Valente, MN; Narayanan, R; Behnia, K; Rodrigues, AD; Brock, B; Smalley, J; Cantor, GH; Lupisella, J; Sleph, P; Grimm, D; Ostrowski, J; Wexler, RR; Kirchgessner, T; Mohan, R Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 49822063 375980334 CHEMBL3945820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583690 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(-c2nnc(C)o2)c(c1)S(C)(=O)=O InChI=1S/C25H29F3N6O5S/c1-6-38-23(35)18-12-29-24(30-21(18)25(26,27)28)34-10-9-33(13-19(34)14(2)3)16-7-8-17(20(11-16)40(5,36)37)22-32-31-15(4)39-22/h7-8,11-12,14,19H,6,9-10,13H2,1-5H3/t19-/m0/s1 UCCCDENCSZIWMM-IBGZPJMESA-N 304396 US10144715, Compound 9-11::ethyl (R)-2-(2-isopropyl-4-(4-(5-methyl-1,3,4-oxadiazol-2-yl)-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 839 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304396&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554461 381753109 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583692 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(-c2ncon2)c(c1)S(C)(=O)=O InChI=1S/C24H27F3N6O5S/c1-5-37-22(34)17-11-28-23(30-20(17)24(25,26)27)33-9-8-32(12-18(33)14(2)3)15-6-7-16(21-29-13-38-31-21)19(10-15)39(4,35)36/h6-7,10-11,13-14,18H,5,8-9,12H2,1-4H3/t18-/m0/s1 NREZKJTZNFMSTC-SFHVURJKSA-N 304397 US10144715, Compound 9-12::ethyl (R)-2-(2-isopropyl-4-(4-(3-methyl-1,2,4-oxadiazol-5-yl)-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 642 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304397&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554462 381753110 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583694 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(-c2nnc(C)s2)c(c1)S(C)(=O)=O InChI=1S/C25H29F3N6O4S2/c1-6-38-23(35)18-12-29-24(30-21(18)25(26,27)28)34-10-9-33(13-19(34)14(2)3)16-7-8-17(20(11-16)40(5,36)37)22-32-31-15(4)39-22/h7-8,11-12,14,19H,6,9-10,13H2,1-5H3/t19-/m0/s1 LUJCWOPVYNTRBQ-IBGZPJMESA-N 304398 US10144715, Compound 9-13::ethyl (R)-2-(2-isopropyl-4-(4-(5-methyl-1,3,4-thiadiazol-2-yl)-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 171 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304398&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554463 381753111 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583696 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(-c2nc(co2)C(N)=O)c(c1)S(C)(=O)=O InChI=1S/C26H29F3N6O6S/c1-5-40-24(37)17-11-31-25(33-21(17)26(27,28)29)35-9-8-34(12-19(35)14(2)3)15-6-7-16(20(10-15)42(4,38)39)23-32-18(13-41-23)22(30)36/h6-7,10-11,13-14,19H,5,8-9,12H2,1-4H3,(H2,30,36)/t19-/m0/s1 UOUJAFCLXIURMD-IBGZPJMESA-N 304399 US10144715, Compound 9-14::ethyl (R)-2-(4-(4-(4-carbamoylthiazol-2-yl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 62.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304399&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554464 381753112 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583698 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28F4N4O3S/c1-13(2)17-12-29(14-6-7-16(23)18(10-14)34(5,32)33)8-9-30(17)20-27-11-15(21(3,4)31)19(28-20)22(24,25)26/h6-7,10-11,13,17,31H,8-9,12H2,1-5H3/t17-/m0/s1 HXOUVMGQDQYWNM-KRWDZBQOSA-N 50177018 CHEMBL3814478::US10144715, Compound 14-1 Oxysterols receptor LXR-beta 8.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883492 346549214 CHEMBL3814478 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583701 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(F)c(c1)S(N)(=O)=O InChI=1S/C21H27F4N5O3S/c1-12(2)16-11-29(13-5-6-15(22)17(9-13)34(26,32)33)7-8-30(16)19-27-10-14(20(3,4)31)18(28-19)21(23,24)25/h5-6,9-10,12,16,31H,7-8,11H2,1-4H3,(H2,26,32,33)/t16-/m0/s1 OKUGPERZNQXECM-INIZCTEOSA-N 304401 (R)-2-fluoro-5-(4-(5-(2-hydroxypropan-2-yl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)benzenesulfonamide::US10144715, Compound 10-2 Oxysterols receptor LXR-beta 34.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304401&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554465 381753114 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583703 CNS(=O)(=O)c1cc(ccc1F)N1CCN([C@@H](C1)C(C)C)c1ncc(c(n1)C(F)(F)F)C(C)(C)O InChI=1S/C22H29F4N5O3S/c1-13(2)17-12-30(14-6-7-16(23)18(10-14)35(33,34)27-5)8-9-31(17)20-28-11-15(21(3,4)32)19(29-20)22(24,25)26/h6-7,10-11,13,17,27,32H,8-9,12H2,1-5H3/t17-/m0/s1 ZFAZSJUOGZNAMM-KRWDZBQOSA-N 304402 (R)-2-fluoro-5-(4-(5-(2-hydroxypropan-2-yl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-N-methylbenzenesulfonamide::US10144715, Compound 10-3 Oxysterols receptor LXR-beta 5.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304402&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554466 381753115 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583705 CC(C)(C)C1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H30F4N4O3S/c1-21(2,3)18-13-30(14-7-8-16(24)17(11-14)35(6,33)34)9-10-31(18)20-28-12-15(22(4,5)32)19(29-20)23(25,26)27/h7-8,11-12,18,32H,9-10,13H2,1-6H3 JUYXKAZFVVUFNZ-UHFFFAOYSA-N 304403 2-(2-(2-(tert-butyl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)propan-2-ol::US10144715, Compound 10-4 Oxysterols receptor LXR-beta 6.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304403&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554467 381753116 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583707 CC(C)[C@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C23H31F3N4O4S/c1-14(2)18-12-29(16-7-6-15(13-31)19(10-16)35(5,33)34)8-9-30(18)21-27-11-17(22(3,4)32)20(28-21)23(24,25)26/h6-7,10-11,14,18,31-32H,8-9,12-13H2,1-5H3/t18-/m1/s1 TVDNBPKRXYLLHY-GOSISDBHSA-N 304404 (S)-2-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)propan-2-ol::US10144715, Compound 10-5 Oxysterols receptor LXR-beta 230 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304404&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554468 381753117 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583708 Cc1nc(ncc1C(C)(C)O)N1CCN(CC1CC(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H26F4N4O3S/c1-13-16(20(2,3)30)11-26-19(27-13)29-8-7-28(12-15(29)10-21(23,24)25)14-5-6-17(22)18(9-14)33(4,31)32/h5-6,9,11,15,30H,7-8,10,12H2,1-4H3 PGBFCYMBTUKVOH-UHFFFAOYSA-N 304405 2-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(2,2,2-trifluoroethyl)piperazin-1-yl)-4-methylpyrimidin-5-yl)propan-2-ol::US10144715, Compound 10-6 Oxysterols receptor LXR-beta 862 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304405&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554469 381753118 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583710 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C23H31F3N4O4S/c1-14(2)18-12-29(16-7-6-15(13-31)19(10-16)35(5,33)34)8-9-30(18)21-27-11-17(22(3,4)32)20(28-21)23(24,25)26/h6-7,10-11,14,18,31-32H,8-9,12-13H2,1-5H3/t18-/m0/s1 TVDNBPKRXYLLHY-SFHVURJKSA-N 304406 (R)-2-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)propan-2-ol::US10144715, Compound 10-7 Oxysterols receptor LXR-beta 18.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304406&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554470 381753119 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583712 CC(C)[C@@H]1CN(CCN1c1nc(c(o1)C(C)(C)O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H27F4N3O4S/c1-12(2)15-11-27(13-6-7-14(22)16(10-13)33(5,30)31)8-9-28(15)19-26-17(21(23,24)25)18(32-19)20(3,4)29/h6-7,10,12,15,29H,8-9,11H2,1-5H3/t15-/m0/s1 HEMSNNYDOIKJMY-HNNXBMFYSA-N 304407 (R)-2-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)oxazol-5-yl)propan-2-ol::US10144715, Compound 10-8 Oxysterols receptor LXR-beta 132 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304407&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883447 381753120 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583713 CC(C)(O)[C@H]1CN(CCN1c1nc(c(o1)C(C)(C)O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H27F4N3O5S/c1-19(2,29)15-11-27(12-6-7-13(22)14(10-12)34(5,31)32)8-9-28(15)18-26-16(21(23,24)25)17(33-18)20(3,4)30/h6-7,10,15,29-30H,8-9,11H2,1-5H3/t15-/m1/s1 YQNBBBZPVLAHGI-OAHLLOKOSA-N 304408 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-1-(6-methyl-5-(trifluoromethyl)pyridin-2-yl)piperazin-2-yl)propan-2-ol::US10144715, Compound 10-9 Oxysterols receptor LXR-beta 2349 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304408&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554471 381753121 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583714 CC(C)(O)[C@@H]1CN(CCN1c1nc(c(o1)C(C)(C)O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H27F4N3O5S/c1-19(2,29)15-11-27(12-6-7-13(22)14(10-12)34(5,31)32)8-9-28(15)18-26-16(21(23,24)25)17(33-18)20(3,4)30/h6-7,10,15,29-30H,8-9,11H2,1-5H3/t15-/m0/s1 YQNBBBZPVLAHGI-HNNXBMFYSA-N 304409 (S)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-1-(6-methyl-5-(trifluoromethyl)pyridin-2-yl)piperazin-2-yl)propan-2-ol::US10144715, Compound 10-10 Oxysterols receptor LXR-beta 181 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304409&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554472 381753122 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583716 CC(C)(O)c1ccc(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C27H32N2O3S/c1-27(2,30)23-14-12-21(13-15-23)19-29-17-16-28(20-26(29)22-8-5-4-6-9-22)24-10-7-11-25(18-24)33(3,31)32/h4-15,18,26,30H,16-17,19-20H2,1-3H3/t26-/m0/s1 BIKUKIZYJIOHPP-SANMLTNESA-N 304410 (R)-2-(4-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 10-11 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304410&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883446 381753123 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583718 CC(C)(O)c1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C27H32N2O3S/c1-27(2,30)23-14-12-21(13-15-23)19-29-17-16-28(20-26(29)22-8-5-4-6-9-22)24-10-7-11-25(18-24)33(3,31)32/h4-15,18,26,30H,16-17,19-20H2,1-3H3/t26-/m1/s1 BIKUKIZYJIOHPP-AREMUKBSSA-N 304411 (S)-2-(4-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 10-12 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304411&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883443 381753124 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583720 CC(C)(O)c1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C27H32N2O3S/c1-27(2,30)23-14-12-21(13-15-23)19-29-17-16-28(20-26(29)22-8-5-4-6-9-22)24-10-7-11-25(18-24)33(3,31)32/h4-15,18,26,30H,16-17,19-20H2,1-3H3/t26-/m1/s1 BIKUKIZYJIOHPP-AREMUKBSSA-N 304411 (S)-2-(4-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 10-12 Oxysterols receptor LXR-beta 1141 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304411&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883443 381753124 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583721 CC(C)(O)c1cc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)ccc1C(F)(F)F InChI=1S/C28H31F3N2O3S/c1-27(2,34)25-16-20(12-13-24(25)28(29,30)31)18-33-15-14-32(19-26(33)21-8-5-4-6-9-21)22-10-7-11-23(17-22)37(3,35)36/h4-13,16-17,26,34H,14-15,18-19H2,1-3H3/t26-/m1/s1 RGJVRKLGNJSKLU-AREMUKBSSA-N 304412 (S)-2-(5-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)-2-(trifluoromethyl)phenyl)propan-2-ol::US10144715, Compound 10-13 Oxysterols receptor LXR-beta 226 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304412&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883444 381753125 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583723 CC(C)(O)c1cc(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)ccc1C(F)(F)F InChI=1S/C28H31F3N2O3S/c1-27(2,34)25-16-20(12-13-24(25)28(29,30)31)18-33-15-14-32(19-26(33)21-8-5-4-6-9-21)22-10-7-11-23(17-22)37(3,35)36/h4-13,16-17,26,34H,14-15,18-19H2,1-3H3/t26-/m0/s1 RGJVRKLGNJSKLU-SANMLTNESA-N 304413 (R)-2-(5-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)-2-(trifluoromethyl)phenyl)propan-2-ol::US10144715, Compound 10-14 Oxysterols receptor LXR-beta 1479 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304413&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883502 381753126 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583725 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O3S/c1-12(2)16-10-27(14-4-5-15(21)17(8-14)32(3,30)31)6-7-28(16)19-25-9-13(11-29)18(26-19)20(22,23)24/h4-5,8-9,12,16,29H,6-7,10-11H2,1-3H3/t16-/m0/s1 QJGPMJDHZAMQSJ-INIZCTEOSA-N 50177017 CHEMBL3815001::US10144715, Compound 11-1 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177017&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883429 346549213 CHEMBL3815001 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583727 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(N)(=O)=O InChI=1S/C19H23F4N5O3S/c1-11(2)15-9-27(13-3-4-14(20)16(7-13)32(24,30)31)5-6-28(15)18-25-8-12(10-29)17(26-18)19(21,22)23/h3-4,7-8,11,15,29H,5-6,9-10H2,1-2H3,(H2,24,30,31)/t15-/m0/s1 GWAZQHKDYABFCB-HNNXBMFYSA-N 304415 (R)-2-fluoro-5-(4-(5-(hydroxymethyl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)benzenesulfonamide::US10144715, Compound 11-2 Oxysterols receptor LXR-beta 35.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304415&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554473 381753128 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583729 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(Cl)c(c1)S(C)(=O)=O InChI=1S/C20H24ClF3N4O3S/c1-12(2)16-10-27(14-4-5-15(21)17(8-14)32(3,30)31)6-7-28(16)19-25-9-13(11-29)18(26-19)20(22,23)24/h4-5,8-9,12,16,29H,6-7,10-11H2,1-3H3/t16-/m0/s1 PAXOTBRHGNYSDC-INIZCTEOSA-N 304416 (R)-(2-(4-(4-chloro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-3 Oxysterols receptor LXR-beta 6.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304416&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554474 381753129 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583731 COC(C)[C@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O5S/c1-13(33-2)17-10-27(16-5-4-14(11-29)18(8-16)34(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t13?,17-/m1/s1 FGQOHZPAZJAOOZ-LRHAYUFXSA-N 304417 (2-((S)-4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-((S)-1-methoxyethyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-4 Oxysterols receptor LXR-beta 159 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304417&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554475 381753130 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583733 COC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O5S/c1-13(33-2)17-10-27(16-5-4-14(11-29)18(8-16)34(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t13?,17-/m0/s1 FGQOHZPAZJAOOZ-RUINGEJQSA-N 304418 (2-((S)-4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-((R)-1-methoxyethyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-5 Oxysterols receptor LXR-beta 414 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304418&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554476 381753131 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583735 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C21H26F4N4O4S/c1-12(2)17-9-28(14-6-16(22)15(11-31)18(7-14)34(3,32)33)4-5-29(17)20-26-8-13(10-30)19(27-20)21(23,24)25/h6-8,12,17,30-31H,4-5,9-11H2,1-3H3/t17-/m0/s1 OLVJJUSAVQHCGI-KRWDZBQOSA-N 304419 (R)-(2-fluoro-4-(4-(5-(hydroxymethyl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-6-(methylsulfonyl)phenyl)methanol::US10144715, Compound 11-6 Oxysterols receptor LXR-beta 2.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304419&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883551 381753132 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583737 CS(=O)(=O)c1cc(ccc1F)N1CCN([C@@H](C1)c1ccc(F)cc1)c1ncc(CO)c(n1)C(F)(F)F InChI=1S/C23H21F5N4O3S/c1-36(34,35)20-10-17(6-7-18(20)25)31-8-9-32(19(12-31)14-2-4-16(24)5-3-14)22-29-11-15(13-33)21(30-22)23(26,27)28/h2-7,10-11,19,33H,8-9,12-13H2,1H3/t19-/m0/s1 PRVFHGDFQQANQD-IBGZPJMESA-N 304420 (R)-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-7 Oxysterols receptor LXR-beta 85.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304420&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554477 381753133 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583739 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nc(C)co2)c(c1)S(C)(=O)=O InChI=1S/C24H28F3N5O4S/c1-14(2)19-11-31(7-8-32(19)23-28-10-16(12-33)21(30-23)24(25,26)27)17-5-6-18(20(9-17)37(4,34)35)22-29-15(3)13-36-22/h5-6,9-10,13-14,19,33H,7-8,11-12H2,1-4H3/t19-/m0/s1 IMRGGTZXUVNBQR-IBGZPJMESA-N 304421 (R)-(2-(2-isopropyl-4-(4-(4-methyloxazol-2-yl)-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-8 Oxysterols receptor LXR-beta 133 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304421&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554478 381753134 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583741 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nnc(C)o2)c(c1)S(C)(=O)=O InChI=1S/C23H27F3N6O4S/c1-13(2)18-11-31(7-8-32(18)22-27-10-15(12-33)20(28-22)23(24,25)26)16-5-6-17(19(9-16)37(4,34)35)21-30-29-14(3)36-21/h5-6,9-10,13,18,33H,7-8,11-12H2,1-4H3/t18-/m0/s1 FZTWXXLUGHOJPX-SFHVURJKSA-N 304422 (R)-(2-(2-isopropyl-4-(4-(5-methyl-1,3,4-oxadiazol-2-yl)-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-9 Oxysterols receptor LXR-beta 247 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304422&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554479 381753135 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583743 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nc(C)no2)c(c1)S(C)(=O)=O InChI=1S/C23H27F3N6O4S/c1-13(2)18-11-31(7-8-32(18)22-27-10-15(12-33)20(29-22)23(24,25)26)16-5-6-17(19(9-16)37(4,34)35)21-28-14(3)30-36-21/h5-6,9-10,13,18,33H,7-8,11-12H2,1-4H3/t18-/m0/s1 VXWZUGIPBINJSC-SFHVURJKSA-N 304423 (R)-(2-(2-isopropyl-4-(4-(3-methyl-1,2,4-oxadiazol-5-yl)-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-10 Oxysterols receptor LXR-beta 773 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304423&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554480 381753136 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583745 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nsc(C)n2)c(c1)S(C)(=O)=O InChI=1S/C23H27F3N6O3S2/c1-13(2)18-11-31(7-8-32(18)22-27-10-15(12-33)20(29-22)23(24,25)26)16-5-6-17(19(9-16)37(4,34)35)21-28-14(3)36-30-21/h5-6,9-10,13,18,33H,7-8,11-12H2,1-4H3/t18-/m0/s1 YNQZLWHGVVVMTP-SFHVURJKSA-N 304424 (R)-(2-(2-isopropyl-4-(4-(5-methyl-1,3,4-thiadiazol-2-yl)-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-11 Oxysterols receptor LXR-beta 246 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304424&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554481 381753137 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583747 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nc(cs2)C#N)c(c1)S(C)(=O)=O InChI=1S/C24H25F3N6O3S2/c1-14(2)19-11-32(6-7-33(19)23-29-10-15(12-34)21(31-23)24(25,26)27)17-4-5-18(20(8-17)38(3,35)36)22-30-16(9-28)13-37-22/h4-5,8,10,13-14,19,34H,6-7,11-12H2,1-3H3/t19-/m0/s1 MQKQOJAXHYOTRU-IBGZPJMESA-N 304425 (R)-2-(4-(4-(5-(hydroxymethyl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)thiazole-4-carbonitrile::US10144715, Compound 11-12 Oxysterols receptor LXR-beta 8.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304425&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883556 381753138 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583749 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nc(co2)C(N)=O)c(c1)S(C)(=O)=O InChI=1S/C24H27F3N6O5S/c1-13(2)18-10-32(6-7-33(18)23-29-9-14(11-34)20(31-23)24(25,26)27)15-4-5-16(19(8-15)39(3,36)37)22-30-17(12-38-22)21(28)35/h4-5,8-9,12-13,18,34H,6-7,10-11H2,1-3H3,(H2,28,35)/t18-/m0/s1 PUFOJDYFCGHZAC-SFHVURJKSA-N 304426 (R)-2-(4-(4-(5-(hydroxymethyl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)thiazole-4-carboxamide::US10144715, Compound 11-13 Oxysterols receptor LXR-beta 65.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304426&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554482 381753139 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583751 Cc1nc(ncc1CO)N1CCN(CC1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C17H21FN4O3S/c1-12-13(11-23)10-19-17(20-12)22-7-5-21(6-8-22)14-3-4-15(18)16(9-14)26(2,24)25/h3-4,9-10,23H,5-8,11H2,1-2H3 VTUORWNMJHMHFV-UHFFFAOYSA-N 304427 (R)-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methylpyrimidin-5-yl)methanol::US10144715, Compound 11-14 Oxysterols receptor LXR-beta 515 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304427&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554483 381753140 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583753 CC(C)[C@@H]1CN(CCN1c1nccc(CO)n1)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C20H28N4O4S/c1-14(2)18-11-23(8-9-24(18)20-21-7-6-16(13-26)22-20)17-5-4-15(12-25)19(10-17)29(3,27)28/h4-7,10,14,18,25-26H,8-9,11-13H2,1-3H3/t18-/m0/s1 FSJYMNFSHTZQMV-SFHVURJKSA-N 304428 (R)-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyrimidin-4-yl)methanol::US10144715, Compound 11-15 Oxysterols receptor LXR-beta 930 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304428&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554484 381753141 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583755 CC(C)[C@@H]1CN(CCN1c1nc(c(CO)o1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C20H26F3N3O5S/c1-12(2)15-9-25(14-5-4-13(10-27)17(8-14)32(3,29)30)6-7-26(15)19-24-18(20(21,22)23)16(11-28)31-19/h4-5,8,12,15,27-28H,6-7,9-11H2,1-3H3/t15-/m0/s1 BGZLLLSITSBZIZ-HNNXBMFYSA-N 304429 (R)-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)oxazol-5-yl)methanol::US10144715, Compound 11-16 Oxysterols receptor LXR-beta 95.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304429&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883433 381753142 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583757 CC(C)[C@@H]1CN(CCN1c1nc(c(CO)s1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C20H26F3N3O4S2/c1-12(2)15-9-25(14-5-4-13(10-27)17(8-14)32(3,29)30)6-7-26(15)19-24-18(20(21,22)23)16(11-28)31-19/h4-5,8,12,15,27-28H,6-7,9-11H2,1-3H3/t15-/m0/s1 LKSBKMBJIBJLPB-HNNXBMFYSA-N 304430 (R)-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)thiazol-5-yl)methanol::US10144715, Compound 11-17 Oxysterols receptor LXR-beta 53.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304430&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883431 381753143 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583759 CC(C)[C@@H]1CN(CCN1c1ncc(C(C)O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H26F4N4O3S/c1-12(2)17-11-28(14-5-6-16(22)18(9-14)33(4,31)32)7-8-29(17)20-26-10-15(13(3)30)19(27-20)21(23,24)25/h5-6,9-10,12-13,17,30H,7-8,11H2,1-4H3/t13?,17-/m0/s1 RPEJMRBNVYJBHP-RUINGEJQSA-N 304431 1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)ethan-1-ol::US10144715, Compound 12-1::US10144715, Compound 13-1 Oxysterols receptor LXR-beta 23.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304431&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883448 381753144 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583761 CC(C)[C@@H]1CN(CCN1c1ncc([C@@H](C)O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H26F4N4O3S/c1-12(2)17-11-28(14-5-6-16(22)18(9-14)33(4,31)32)7-8-29(17)20-26-10-15(13(3)30)19(27-20)21(23,24)25/h5-6,9-10,12-13,17,30H,7-8,11H2,1-4H3/t13-,17+/m1/s1 RPEJMRBNVYJBHP-DYVFJYSZSA-N 304432 (S)-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)ethan-1-ol::US10144715, Compound 12-2 Oxysterols receptor LXR-beta 11.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304432&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554485 381753145 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583763 CC(C)[C@@H]1CN(CCN1c1ncc([C@H](C)O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H26F4N4O3S/c1-12(2)17-11-28(14-5-6-16(22)18(9-14)33(4,31)32)7-8-29(17)20-26-10-15(13(3)30)19(27-20)21(23,24)25/h5-6,9-10,12-13,17,30H,7-8,11H2,1-4H3/t13-,17-/m0/s1 RPEJMRBNVYJBHP-GUYCJALGSA-N 304433 (R)-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)ethan-1-ol::US10144715, Compound 12-3 Oxysterols receptor LXR-beta 6.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304433&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554486 381753146 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583765 CC(C)[C@@H]1CN(CCN1c1ncc([C@@H](C)O)c(n1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C22H26F3N5O3S/c1-13(2)18-12-29(16-6-5-15(10-26)19(9-16)34(4,32)33)7-8-30(18)21-27-11-17(14(3)31)20(28-21)22(23,24)25/h5-6,9,11,13-14,18,31H,7-8,12H2,1-4H3/t14-,18+/m1/s1 WHVQPSGLEDLTIG-KDOFPFPSSA-N 304434 4-((R)-4-(5-((R)-1-hydroxyethyl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 12-4 Oxysterols receptor LXR-beta 111 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304434&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554487 381753147 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583767 CC(C)[C@@H]1CN(CCN1c1ncc([C@H](C)O)c(n1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C22H26F3N5O3S/c1-13(2)18-12-29(16-6-5-15(10-26)19(9-16)34(4,32)33)7-8-30(18)21-27-11-17(14(3)31)20(28-21)22(23,24)25/h5-6,9,11,13-14,18,31H,7-8,12H2,1-4H3/t14-,18-/m0/s1 WHVQPSGLEDLTIG-KSSFIOAISA-N 304435 4-((R)-4-(5-((S)-1-hydroxyethyl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 12-5 Oxysterols receptor LXR-beta 80.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304435&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554488 381753148 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583769 CC[C@H](O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28F4N4O3S/c1-5-18(31)15-11-27-21(28-20(15)22(24,25)26)30-9-8-29(12-17(30)13(2)3)14-6-7-16(23)19(10-14)34(4,32)33/h6-7,10-11,13,17-18,31H,5,8-9,12H2,1-4H3/t17-,18-/m0/s1 YIRPKYOIUDNERT-ROUUACIJSA-N 304436 (S)-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)propan-1-ol::US10144715, Compound 12-6 Oxysterols receptor LXR-beta 22.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304436&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554489 381753149 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583771 CC[C@@H](O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28F4N4O3S/c1-5-18(31)15-11-27-21(28-20(15)22(24,25)26)30-9-8-29(12-17(30)13(2)3)14-6-7-16(23)19(10-14)34(4,32)33/h6-7,10-11,13,17-18,31H,5,8-9,12H2,1-4H3/t17-,18+/m0/s1 YIRPKYOIUDNERT-ZWKOTPCHSA-N 304437 (R)-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)propan-1-ol::US10144715, Compound 12-7 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304437&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883548 381753150 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583773 CNS(=O)(=O)c1cc(ccc1F)N1CCN([C@@H](C1)C(C)C)c1ncc(C(C)O)c(n1)C(F)(F)F InChI=1S/C21H27F4N5O3S/c1-12(2)17-11-29(14-5-6-16(22)18(9-14)34(32,33)26-4)7-8-30(17)20-27-10-15(13(3)31)19(28-20)21(23,24)25/h5-6,9-10,12-13,17,26,31H,7-8,11H2,1-4H3/t13?,17-/m0/s1 GCGBTTGCZAXGLQ-RUINGEJQSA-N 304438 2-fluoro-5-((3R)-4-(5-(1-hydroxyethyl)-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-N-methylbenzenesulfonamide::US10144715, Compound 12-8 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304438&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554490 381753151 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583775 C[C@H](O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1c1ccc(F)cc1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H23F5N4O3S/c1-14(34)18-12-30-23(31-22(18)24(27,28)29)33-10-9-32(13-20(33)15-3-5-16(25)6-4-15)17-7-8-19(26)21(11-17)37(2,35)36/h3-8,11-12,14,20,34H,9-10,13H2,1-2H3/t14-,20-/m0/s1 SAKQPFIBVKAZMM-XOBRGWDASA-N 304439 1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)ethan-1-ol::US10144715, Compound 12-9 Oxysterols receptor LXR-beta 132 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304439&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554491 381753152 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583777 CC(C)[C@@H]1CN(CCN1c1ncc(C(C)O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H26F4N4O3S/c1-12(2)17-11-28(14-5-6-16(22)18(9-14)33(4,31)32)7-8-29(17)20-26-10-15(13(3)30)19(27-20)21(23,24)25/h5-6,9-10,12-13,17,30H,7-8,11H2,1-4H3/t13?,17-/m0/s1 RPEJMRBNVYJBHP-RUINGEJQSA-N 304431 1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)ethan-1-ol::US10144715, Compound 12-1::US10144715, Compound 13-1 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304431&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883448 381753144 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583778 CNS(=O)(=O)c1cc(ccc1F)N1CCN([C@@H](C1)c1ccc(F)cc1)c1ncc(C(C)=O)c(n1)C(F)(F)F InChI=1S/C24H22F5N5O3S/c1-14(35)18-12-31-23(32-22(18)24(27,28)29)34-10-9-33(13-20(34)15-3-5-16(25)6-4-15)17-7-8-19(26)21(11-17)38(36,37)30-2/h3-8,11-12,20,30H,9-10,13H2,1-2H3/t20-/m0/s1 MXGAWJHHWQSRGH-FQEVSTJZSA-N 304441 (R)-5-(4-(5-acetyl-4-(trifluoromethyl)pyrimidin-2-yl)-3-isopropylpiperazin-1-yl)-2-fluoro-N-methylbenzenesulfonamide::US10144715, Compound 13-2 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304441&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554492 381753153 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583779 CC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1c1ccc(F)cc1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H21F5N4O3S/c1-14(34)18-12-30-23(31-22(18)24(27,28)29)33-10-9-32(13-20(33)15-3-5-16(25)6-4-15)17-7-8-19(26)21(11-17)37(2,35)36/h3-8,11-12,20H,9-10,13H2,1-2H3/t20-/m0/s1 IVNMKTKQRQEZRZ-FQEVSTJZSA-N 304442 (R)-1-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)ethan-1-one::US10144715, Compound 13-3 Oxysterols receptor LXR-beta 88.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304442&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883434 381753154 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583781 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)O)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28F4N4O3S/c1-13(2)17-12-29(14-6-7-16(23)18(10-14)34(5,32)33)8-9-30(17)20-27-11-15(21(3,4)31)19(28-20)22(24,25)26/h6-7,10-11,13,17,31H,8-9,12H2,1-5H3/t17-/m0/s1 HXOUVMGQDQYWNM-KRWDZBQOSA-N 50177018 CHEMBL3814478::US10144715, Compound 14-1 Oxysterols receptor LXR-beta 14.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883492 346549214 CHEMBL3814478 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583782 CC(C)[C@@H]1CN(CCN1c1ncc(C(C)=C)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C23H29F3N4O3S/c1-14(2)18-11-27-22(28-21(18)23(24,25)26)30-9-8-29(12-19(30)15(3)4)17-7-6-16(13-31)20(10-17)34(5,32)33/h6-7,10-11,15,19,31H,1,8-9,12-13H2,2-5H3/t19-/m0/s1 ZIFRSVSKYBFYNR-IBGZPJMESA-N 304444 (R)-(4-(3-isopropyl-4-(5-(prop-1-en-2-yl)-4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 14-2 Oxysterols receptor LXR-beta 1.000 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304444&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883435 381753156 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583784 CC(C)[C@@H]1CN(CCN1c1ncc(CN2CC(F)C2)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H28F5N5O2S/c1-14(2)19-13-32(17-4-5-18(25)20(8-17)36(3,34)35)6-7-33(19)22-29-9-15(10-31-11-16(24)12-31)21(30-22)23(26,27)28/h4-5,8-9,14,16,19H,6-7,10-13H2,1-3H3/t19-/m0/s1 WQLPRQYFFAOTOS-IBGZPJMESA-N 304445 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-((3-fluoroazetidin-1-yl)methyl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 15-1 Oxysterols receptor LXR-beta 16.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304445&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883453 381753157 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583786 CC(C)[C@@H]1CN(CCN1c1ncc(CN)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H25F4N5O2S/c1-12(2)16-11-28(14-4-5-15(21)17(8-14)32(3,30)31)6-7-29(16)19-26-10-13(9-25)18(27-19)20(22,23)24/h4-5,8,10,12,16H,6-7,9,11,25H2,1-3H3/t16-/m0/s1 SCVHIRJCMCWHFT-INIZCTEOSA-N 304446 (R)-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanamine::US10144715, Compound 15-2 Oxysterols receptor LXR-beta 1320 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304446&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554493 381753158 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583787 CC(C)[C@@H]1CN(CCN1c1ncc(CN(C)C)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H29F4N5O2S/c1-14(2)18-13-30(16-6-7-17(23)19(10-16)34(5,32)33)8-9-31(18)21-27-11-15(12-29(3)4)20(28-21)22(24,25)26/h6-7,10-11,14,18H,8-9,12-13H2,1-5H3/t18-/m0/s1 ZFQQCVQAIJVKJV-SFHVURJKSA-N 304447 (R)-1-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)-N,N-dimethylmethanamine::US10144715, Compound 15-3 Oxysterols receptor LXR-beta 47.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304447&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554494 381753159 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583788 CC(C)[C@@H]1CN(CCN1c1ncc(CN2CC(O)C2)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H29F4N5O3S/c1-14(2)19-13-31(16-4-5-18(24)20(8-16)36(3,34)35)6-7-32(19)22-28-9-15(10-30-11-17(33)12-30)21(29-22)23(25,26)27/h4-5,8-9,14,17,19,33H,6-7,10-13H2,1-3H3/t19-/m0/s1 MPLPRRMGXFNRNX-IBGZPJMESA-N 304448 (R)-1-((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)azetidin-3-ol::US10144715, Compound 15-4 Oxysterols receptor LXR-beta 100.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304448&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554495 381753160 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583789 CC(C)[C@@H]1CN(CCN1c1ncc(CN2CCOCC2)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H31F4N5O3S/c1-16(2)20-15-32(18-4-5-19(25)21(12-18)37(3,34)35)6-7-33(20)23-29-13-17(22(30-23)24(26,27)28)14-31-8-10-36-11-9-31/h4-5,12-13,16,20H,6-11,14-15H2,1-3H3/t20-/m0/s1 TVOZQSJSRZPOLF-FQEVSTJZSA-N 304449 (R)-4-((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)morpholine::US10144715, Compound 15-5 Oxysterols receptor LXR-beta 36.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304449&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883533 381753161 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583791 CC(C)[C@@H]1CN(CCN1c1ncc(CN(C)C(C)(C)C)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C25H35F4N5O2S/c1-16(2)20-15-33(18-8-9-19(26)21(12-18)37(7,35)36)10-11-34(20)23-30-13-17(14-32(6)24(3,4)5)22(31-23)25(27,28)29/h8-9,12-13,16,20H,10-11,14-15H2,1-7H3/t20-/m0/s1 YUAFTNMFRDULEH-FQEVSTJZSA-N 304450 (R)-N-((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)-N,2-dimethylpropan-2-amine::US10144715, Compound 15-6 Oxysterols receptor LXR-beta 360 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304450&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554496 381753162 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583793 CC(C)[C@@H]1CN(CCN1c1ncc(CNS(C)(=O)=O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H27F4N5O4S2/c1-13(2)17-12-29(15-5-6-16(22)18(9-15)35(3,31)32)7-8-30(17)20-26-10-14(11-27-36(4,33)34)19(28-20)21(23,24)25/h5-6,9-10,13,17,27H,7-8,11-12H2,1-4H3/t17-/m0/s1 QQVBOEBRRVCOPV-KRWDZBQOSA-N 304451 (R)-N-((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)methanesulfonamide::US10144715, Compound 15-7 Oxysterols receptor LXR-beta 40.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304451&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554497 381753163 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583794 CSCc1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H26F4N4O2S2/c1-13(2)17-11-28(15-5-6-16(22)18(9-15)33(4,30)31)7-8-29(17)20-26-10-14(12-32-3)19(27-20)21(23,24)25/h5-6,9-10,13,17H,7-8,11-12H2,1-4H3/t17-/m0/s1 GBVDPBLFWAPJJL-KRWDZBQOSA-N 304452 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-((methylthio)methyl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 15-8 Oxysterols receptor LXR-beta 1.000 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304452&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554498 381753164 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583796 CC(C)[C@@H]1CN(CCN1c1ncc(CN(C)CCCO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C25H36F3N5O4S/c1-17(2)21-15-32(20-7-6-18(16-35)22(12-20)38(4,36)37)9-10-33(21)24-29-13-19(14-31(3)8-5-11-34)23(30-24)25(26,27)28/h6-7,12-13,17,21,34-35H,5,8-11,14-16H2,1-4H3/t21-/m0/s1 NFNVONRUBGQUCN-NRFANRHFSA-N 304453 (R)-3-(((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)(methyl)amino)propan-1-ol::US10144715, Compound 15-9 Oxysterols receptor LXR-beta 146 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304453&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554499 381753165 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583798 COCCN(C)Cc1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C25H36F3N5O4S/c1-17(2)21-15-32(20-7-6-18(16-34)22(12-20)38(5,35)36)8-9-33(21)24-29-13-19(14-31(3)10-11-37-4)23(30-24)25(26,27)28/h6-7,12-13,17,21,34H,8-11,14-16H2,1-5H3/t21-/m0/s1 AGRFKQNRWVWUFL-NRFANRHFSA-N 304454 (R)-N-((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)-2-methoxy-N-methylethan-1-amine::US10144715, Compound 15-10 Oxysterols receptor LXR-beta 70.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304454&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554500 381753166 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583800 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(CN)c(c1)S(C)(=O)=O InChI=1S/C20H26F3N5O2S/c1-13(2)16-12-27(15-5-4-14(11-24)17(10-15)31(3,29)30)8-9-28(16)19-25-7-6-18(26-19)20(21,22)23/h4-7,10,13,16H,8-9,11-12,24H2,1-3H3/t16-/m0/s1 SYKOYQXWANTFOT-INIZCTEOSA-N 304455 (R)-(4-(3-isopropyl-4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanamine::US10144715, Compound 15-11 Oxysterols receptor LXR-beta 228 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304455&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883455 381753167 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583802 CC(C)[C@@H]1CN(CCN1c1ncc(C(O)=O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H22F4N4O4S/c1-11(2)15-10-27(12-4-5-14(21)16(8-12)33(3,31)32)6-7-28(15)19-25-9-13(18(29)30)17(26-19)20(22,23)24/h4-5,8-9,11,15H,6-7,10H2,1-3H3,(H,29,30)/t15-/m0/s1 XYPNFBOCCSMVND-HNNXBMFYSA-N 304456 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylic acid::US10144715, Compound 16-1 Oxysterols receptor LXR-beta 1856 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304456&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883503 381753168 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583804 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N(C)C)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H27F4N5O3S/c1-13(2)17-12-30(14-6-7-16(23)18(10-14)35(5,33)34)8-9-31(17)21-27-11-15(20(32)29(3)4)19(28-21)22(24,25)26/h6-7,10-11,13,17H,8-9,12H2,1-5H3/t17-/m0/s1 VIUNJILCBMZNGS-KRWDZBQOSA-N 304457 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N,N-dimethyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-1 Oxysterols receptor LXR-beta 123 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304457&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883566 381753169 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583806 CC(C)[C@@H]1CN(CCN1c1ncc(C(N)=O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23F4N5O3S/c1-11(2)15-10-28(12-4-5-14(21)16(8-12)33(3,31)32)6-7-29(15)19-26-9-13(18(25)30)17(27-19)20(22,23)24/h4-5,8-9,11,15H,6-7,10H2,1-3H3,(H2,25,30)/t15-/m0/s1 OXFIAOBJWCENMG-HNNXBMFYSA-N 304458 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-2 Oxysterols receptor LXR-beta 58.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304458&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554501 381753170 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583808 CNC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H25F4N5O3S/c1-12(2)16-11-29(13-5-6-15(22)17(9-13)34(4,32)33)7-8-30(16)20-27-10-14(19(31)26-3)18(28-20)21(23,24)25/h5-6,9-10,12,16H,7-8,11H2,1-4H3,(H,26,31)/t16-/m0/s1 HMTKGKLPOFXDLH-INIZCTEOSA-N 304459 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-3 Oxysterols receptor LXR-beta 188 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304459&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554502 381753171 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583809 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N2CC(N)C2)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H28F4N6O3S/c1-13(2)18-12-31(15-4-5-17(24)19(8-15)37(3,35)36)6-7-33(18)22-29-9-16(20(30-22)23(25,26)27)21(34)32-10-14(28)11-32/h4-5,8-9,13-14,18H,6-7,10-12,28H2,1-3H3/t18-/m0/s1 DEUPHGQOWVRUGY-SFHVURJKSA-N 304460 (R)-(3-aminoazetidin-1-yl)(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanone::US10144715, Compound 17-4 Oxysterols receptor LXR-beta 512 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304460&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554503 381753172 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583810 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N2CC(O)C2)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H27F4N5O4S/c1-13(2)18-12-30(14-4-5-17(24)19(8-14)37(3,35)36)6-7-32(18)22-28-9-16(20(29-22)23(25,26)27)21(34)31-10-15(33)11-31/h4-5,8-9,13,15,18,33H,6-7,10-12H2,1-3H3/t18-/m0/s1 MFTZSHAAXAHNHC-SFHVURJKSA-N 304461 (R)-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)(3-hydroxyazetidin-1-yl)methanone::US10144715, Compound 17-5 Oxysterols receptor LXR-beta 396 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304461&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554504 381753173 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583812 COCCNC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H29F4N5O4S/c1-14(2)18-13-31(15-5-6-17(24)19(11-15)37(4,34)35)8-9-32(18)22-29-12-16(20(30-22)23(25,26)27)21(33)28-7-10-36-3/h5-6,11-12,14,18H,7-10,13H2,1-4H3,(H,28,33)/t18-/m0/s1 ZVCFPNXEKVIWFT-SFHVURJKSA-N 304462 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(2-methoxyethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-6 Oxysterols receptor LXR-beta 532 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304462&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554505 381753174 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583814 COCCN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H31F4N5O4S/c1-15(2)19-14-32(16-6-7-18(25)20(12-16)38(5,35)36)8-9-33(19)23-29-13-17(21(30-23)24(26,27)28)22(34)31(3)10-11-37-4/h6-7,12-13,15,19H,8-11,14H2,1-5H3/t19-/m0/s1 JPWAMIWBXUQEHC-IBGZPJMESA-N 304463 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(2-hydroxyethyl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::BDBM304468::US10144715, Compound 17-7 Oxysterols receptor LXR-beta 507 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304463&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554506 381753175 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583815 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N2CCOCC2)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H29F4N5O4S/c1-15(2)19-14-32(16-4-5-18(25)20(12-16)38(3,35)36)6-7-33(19)23-29-13-17(21(30-23)24(26,27)28)22(34)31-8-10-37-11-9-31/h4-5,12-13,15,19H,6-11,14H2,1-3H3/t19-/m0/s1 DOEBDJZFBMJVEE-IBGZPJMESA-N 304464 (R)-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)(morpholino)methanone::US10144715, Compound 17-8 Oxysterols receptor LXR-beta 311 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304464&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554507 381753176 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583817 COC1CN(C1)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H29F4N5O4S/c1-14(2)19-13-31(15-5-6-18(25)20(9-15)38(4,35)36)7-8-33(19)23-29-10-17(21(30-23)24(26,27)28)22(34)32-11-16(12-32)37-3/h5-6,9-10,14,16,19H,7-8,11-13H2,1-4H3/t19-/m0/s1 WOKSFDXOXBDKOP-IBGZPJMESA-N 304465 (R)-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)(3-methoxyazetidin-1-yl)methanone::US10144715, Compound 17-9 Oxysterols receptor LXR-beta 410 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304465&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554508 381753177 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583819 CCCCN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C25H33F4N5O3S/c1-6-7-10-32(4)23(35)18-14-30-24(31-22(18)25(27,28)29)34-12-11-33(15-20(34)16(2)3)17-8-9-19(26)21(13-17)38(5,36)37/h8-9,13-14,16,20H,6-7,10-12,15H2,1-5H3/t20-/m0/s1 MXMNSPKGWWEDFT-FQEVSTJZSA-N 304466 (R)-N-butyl-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-10 Oxysterols receptor LXR-beta 65.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304466&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554509 381753178 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583821 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N(C)CCCO)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H31F4N5O4S/c1-15(2)19-14-32(16-6-7-18(25)20(12-16)38(4,36)37)9-10-33(19)23-29-13-17(21(30-23)24(26,27)28)22(35)31(3)8-5-11-34/h6-7,12-13,15,19,34H,5,8-11,14H2,1-4H3/t19-/m0/s1 LDXNZPNNJRMAHP-IBGZPJMESA-N 304467 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(3-hydroxypropyl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-11 Oxysterols receptor LXR-beta 548 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304467&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554510 381753179 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583822 COCCN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H31F4N5O4S/c1-15(2)19-14-32(16-6-7-18(25)20(12-16)38(5,35)36)8-9-33(19)23-29-13-17(21(30-23)24(26,27)28)22(34)31(3)10-11-37-4/h6-7,12-13,15,19H,8-11,14H2,1-5H3/t19-/m0/s1 JPWAMIWBXUQEHC-IBGZPJMESA-N 304463 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(2-hydroxyethyl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::BDBM304468::US10144715, Compound 17-7 Oxysterols receptor LXR-beta 210 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304463&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554506 381753175 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583824 COCCCN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C25H33F4N5O4S/c1-16(2)20-15-33(17-7-8-19(26)21(13-17)39(5,36)37)10-11-34(20)24-30-14-18(22(31-24)25(27,28)29)23(35)32(3)9-6-12-38-4/h7-8,13-14,16,20H,6,9-12,15H2,1-5H3/t20-/m0/s1 ZHOTZEBFAJOXIP-FQEVSTJZSA-N 304469 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(3-methoxypropyl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-13 Oxysterols receptor LXR-beta 253 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304469&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554511 381753181 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583826 CCN(CCOC)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C25H33F4N5O4S/c1-6-32(11-12-38-4)23(35)18-14-30-24(31-22(18)25(27,28)29)34-10-9-33(15-20(34)16(2)3)17-7-8-19(26)21(13-17)39(5,36)37/h7-8,13-14,16,20H,6,9-12,15H2,1-5H3/t20-/m0/s1 XXHQLZDZSDSOOP-FQEVSTJZSA-N 304470 (R)-N-ethyl-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(2-methoxyethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-14 Oxysterols receptor LXR-beta 113 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304470&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554512 381753182 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583828 CCN(CCCO)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C25H33F4N5O4S/c1-5-32(9-6-12-35)23(36)18-14-30-24(31-22(18)25(27,28)29)34-11-10-33(15-20(34)16(2)3)17-7-8-19(26)21(13-17)39(4,37)38/h7-8,13-14,16,20,35H,5-6,9-12,15H2,1-4H3/t20-/m0/s1 BQUPGIQBGWZZCZ-FQEVSTJZSA-N 304471 (R)-N-ethyl-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(3-hydroxypropyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-15 Oxysterols receptor LXR-beta 360 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304471&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554513 381753183 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583830 CCOC(=O)CN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C25H31F4N5O5S/c1-6-39-21(35)14-32(4)23(36)17-12-30-24(31-22(17)25(27,28)29)34-10-9-33(13-19(34)15(2)3)16-7-8-18(26)20(11-16)40(5,37)38/h7-8,11-12,15,19H,6,9-10,13-14H2,1-5H3/t19-/m0/s1 XFAQBXLSWRWWKJ-IBGZPJMESA-N 304472 US10144715, Compound 17-16::ethyl (R)-N-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carbonyl)-N-methylglycinate Oxysterols receptor LXR-beta 194 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304472&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554514 381753184 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583832 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N(C)CCC(C)(C)O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C26H35F4N5O4S/c1-16(2)20-15-34(17-7-8-19(27)21(13-17)40(6,38)39)11-12-35(20)24-31-14-18(22(32-24)26(28,29)30)23(36)33(5)10-9-25(3,4)37/h7-8,13-14,16,20,37H,9-12,15H2,1-6H3/t20-/m0/s1 NINANRXFCHNAGM-FQEVSTJZSA-N 304473 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(3-hydroxy-3-methylbutyl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-17 Oxysterols receptor LXR-beta 618 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304473&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554515 381753185 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583833 CCOC(=O)CCN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C26H33F4N5O5S/c1-6-40-22(36)9-10-33(4)24(37)18-14-31-25(32-23(18)26(28,29)30)35-12-11-34(15-20(35)16(2)3)17-7-8-19(27)21(13-17)41(5,38)39/h7-8,13-14,16,20H,6,9-12,15H2,1-5H3/t20-/m0/s1 RLXFHRVQCKQUFX-FQEVSTJZSA-N 304474 US10144715, Compound 17-18::ethyl (R)-3-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamido)propanoate Oxysterols receptor LXR-beta 129 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304474&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554516 381753186 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583835 COC(=O)NCCCN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C26H34F4N6O5S/c1-16(2)20-15-35(17-7-8-19(27)21(13-17)42(5,39)40)11-12-36(20)24-32-14-18(22(33-24)26(28,29)30)23(37)34(3)10-6-9-31-25(38)41-4/h7-8,13-14,16,20H,6,9-12,15H2,1-5H3,(H,31,38)/t20-/m0/s1 ZDIDVXLVHPIVDA-FQEVSTJZSA-N 304475 US10144715, Compound 17-19::methyl (R)-(3-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamido)propyl)carbamate Oxysterols receptor LXR-beta 584 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304475&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554517 381753187 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583836 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)NC2CN(C2)C(=O)OC(C)(C)C)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C28H36F4N6O5S/c1-16(2)21-15-36(18-7-8-20(29)22(11-18)44(6,41)42)9-10-38(21)25-33-12-19(23(35-25)28(30,31)32)24(39)34-17-13-37(14-17)26(40)43-27(3,4)5/h7-8,11-12,16-17,21H,9-10,13-15H2,1-6H3,(H,34,39)/t21-/m0/s1 MRSGTZCQBFNLOD-NRFANRHFSA-N 304476 US10144715, Compound 17-20::tert-butyl (R)-3-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamido)azetidine-1-carboxylate Oxysterols receptor LXR-beta 330 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304476&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554518 381753188 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583837 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N2CC(C2)NC(=O)OC(C)(C)C)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C28H36F4N6O5S/c1-16(2)21-15-36(18-7-8-20(29)22(11-18)44(6,41)42)9-10-38(21)25-33-12-19(23(35-25)28(30,31)32)24(39)37-13-17(14-37)34-26(40)43-27(3,4)5/h7-8,11-12,16-17,21H,9-10,13-15H2,1-6H3,(H,34,40)/t21-/m0/s1 RYEAJKPHPMYJBZ-NRFANRHFSA-N 304477 US10144715, Compound 17-21::tert-butyl (R)-(1-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carbonyl)azetidin-3-yl)carbamate Oxysterols receptor LXR-beta 111 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304477&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554519 381753189 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583839 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N(C)C2CN(C2)C(=O)OC(C)(C)C)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C29H38F4N6O5S/c1-17(2)22-16-37(18-8-9-21(30)23(12-18)45(7,42)43)10-11-39(22)26-34-13-20(24(35-26)29(31,32)33)25(40)36(6)19-14-38(15-19)27(41)44-28(3,4)5/h8-9,12-13,17,19,22H,10-11,14-16H2,1-7H3/t22-/m0/s1 OZKKLFAIQTYTBH-QFIPXVFZSA-N 304478 US10144715, Compound 17-22::tert-butyl (R)-3-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamido)azetidine-1-carboxylate Oxysterols receptor LXR-beta 116 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304478&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554520 381753190 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583841 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N(C)CCCNC(=O)OC(C)(C)C)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C29H40F4N6O5S/c1-18(2)22-17-38(19-9-10-21(30)23(15-19)45(7,42)43)13-14-39(22)26-35-16-20(24(36-26)29(31,32)33)25(40)37(6)12-8-11-34-27(41)44-28(3,4)5/h9-10,15-16,18,22H,8,11-14,17H2,1-7H3,(H,34,41)/t22-/m0/s1 GWSXDOMHSSTAEH-QFIPXVFZSA-N 304479 US10144715, Compound 17-23::tert-butyl (R)-(3-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamido)propyl)carbamate Oxysterols receptor LXR-beta 257 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304479&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554521 381753191 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583843 CC(C)[C@@H]1CN(CCN1c1ncc(C(N)=O)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H26FN5O3S/c1-12(2)17-11-25(14-5-6-16(21)18(9-14)30(4,28)29)7-8-26(17)20-23-10-15(19(22)27)13(3)24-20/h5-6,9-10,12,17H,7-8,11H2,1-4H3,(H2,22,27)/t17-/m0/s1 JOWNILHVWUBBAX-KRWDZBQOSA-N 304480 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methylpyrimidine-5-carboxamide::US10144715, Compound 17-24 Oxysterols receptor LXR-beta 611 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304480&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554522 381753192 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583845 CC(C)[C@@H]1CN(CCN1c1ncc(C(N)=O)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H26F3N5O4S/c1-12(2)16-10-28(14-5-4-13(11-30)17(8-14)34(3,32)33)6-7-29(16)20-26-9-15(19(25)31)18(27-20)21(22,23)24/h4-5,8-9,12,16,30H,6-7,10-11H2,1-3H3,(H2,25,31)/t16-/m0/s1 ADICZSLMBXEJLA-INIZCTEOSA-N 304481 (R)-2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-25 Oxysterols receptor LXR-beta 50.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304481&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883531 381753193 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583847 COCCN(C)C(=O)c1cnc(nc1C)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H34FN5O4S/c1-16(2)21-15-29(18-7-8-20(25)22(13-18)35(6,32)33)9-10-30(21)24-26-14-19(17(3)27-24)23(31)28(4)11-12-34-5/h7-8,13-14,16,21H,9-12,15H2,1-6H3/t21-/m0/s1 KUNWPYJWJBTYDG-NRFANRHFSA-N 304482 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(2-methoxyethyl)-N,4-dimethylpyrimidine-5-carboxamide::US10144715, Compound 17-26 Oxysterols receptor LXR-beta 2334 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304482&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554523 381753194 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583849 CC(C)[C@@H]1CN(CCN1c1ncc(C(=O)N(C)CCCO)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H34FN5O4S/c1-16(2)21-15-29(18-7-8-20(25)22(13-18)35(5,33)34)10-11-30(21)24-26-14-19(17(3)27-24)23(32)28(4)9-6-12-31/h7-8,13-14,16,21,31H,6,9-12,15H2,1-5H3/t21-/m0/s1 XWAYZPOBLODOQF-NRFANRHFSA-N 304483 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(3-hydroxypropyl)-N,4-dimethylpyrimidine-5-carboxamide::US10144715, Compound 17-27 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304483&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554524 381753195 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583851 CC(C)[C@@H]1CN(CCN1c1ncc(C(N)=O)c(n1)C(F)(F)F)c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C21H25F4N5O4S/c1-11(2)16-9-29(12-6-15(22)14(10-31)17(7-12)35(3,33)34)4-5-30(16)20-27-8-13(19(26)32)18(28-20)21(23,24)25/h6-8,11,16,31H,4-5,9-10H2,1-3H3,(H2,26,32)/t16-/m0/s1 RMPXFIICIICDOD-INIZCTEOSA-N 304484 (R)-2-(4-(3-fluoro-4-(hydroxymethyl)-5-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-28 Oxysterols receptor LXR-beta 34.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304484&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883532 381753196 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583853 CC(C)[C@@H]1CN(CCN1c1ncc(C(N)=O)c(n1)C(F)(F)F)c1cc(c(CO)cc1F)S(C)(=O)=O InChI=1S/C21H25F4N5O4S/c1-11(2)16-9-29(15-7-17(35(3,33)34)12(10-31)6-14(15)22)4-5-30(16)20-27-8-13(19(26)32)18(28-20)21(23,24)25/h6-8,11,16,31H,4-5,9-10H2,1-3H3,(H2,26,32)/t16-/m0/s1 OTGGBYJANKCUNX-INIZCTEOSA-N 304485 (R)-2-(4-(2-fluoro-4-(hydroxymethyl)-5-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-29 Oxysterols receptor LXR-beta 191 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304485&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554525 381753197 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583855 CCN(CCOC)C(=O)c1cnc(nc1C)N1CCN(C[C@H]1C(C)C)c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C26H38FN5O5S/c1-7-30(10-11-37-5)25(34)20-14-28-26(29-18(20)4)32-9-8-31(15-23(32)17(2)3)19-12-22(27)21(16-33)24(13-19)38(6,35)36/h12-14,17,23,33H,7-11,15-16H2,1-6H3/t23-/m0/s1 XOCPFRIMEXAGFK-QHCPKHFHSA-N 304486 (R)-N-ethyl-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(2-methoxyethyl)-4-methylpyrimidine-5-carboxamide::US10144715, Compound 17-30 Oxysterols receptor LXR-beta 1804 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304486&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554526 381753198 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583857 COCCCN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C26H35F4N5O5S/c1-16(2)21-14-34(17-11-20(27)19(15-36)22(12-17)41(5,38)39)8-9-35(21)25-31-13-18(23(32-25)26(28,29)30)24(37)33(3)7-6-10-40-4/h11-13,16,21,36H,6-10,14-15H2,1-5H3/t21-/m0/s1 SVCMCUFOCGWFHA-NRFANRHFSA-N 304487 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N-(3-methoxypropyl)-N,4-dimethylpyrimidine-5-carboxamide::US10144715, Compound 17-31 Oxysterols receptor LXR-beta 2448 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304487&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554527 381753199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583858 CON(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1c1ccc(F)cc1)c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C26H26F5N5O5S/c1-34(41-2)24(38)18-12-32-25(33-23(18)26(29,30)31)36-9-8-35(13-21(36)15-4-6-16(27)7-5-15)17-10-20(28)19(14-37)22(11-17)42(3,39)40/h4-7,10-12,21,37H,8-9,13-14H2,1-3H3/t21-/m0/s1 BMHCFESQJZXOSE-NRFANRHFSA-N 304488 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)piperazin-1-yl)-N-methoxy-N-methyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-32 Oxysterols receptor LXR-beta 435 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304488&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554528 381753200 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583860 CN(C)C(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1c1ccc(F)cc1)c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C26H26F5N5O4S/c1-34(2)24(38)18-12-32-25(33-23(18)26(29,30)31)36-9-8-35(13-21(36)15-4-6-16(27)7-5-15)17-10-20(28)19(14-37)22(11-17)41(3,39)40/h4-7,10-12,21,37H,8-9,13-14H2,1-3H3/t21-/m0/s1 AKSRNYCCIKYVHG-NRFANRHFSA-N 304489 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)piperazin-1-yl)-N,N-dimethyl-4-(trifluoromethyl)pyrimidine-5-carboxamide::US10144715, Compound 17-33 Oxysterols receptor LXR-beta 1224 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304489&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554529 381753201 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583862 CC(C)[C@@H]1CN(CCN1c1nc(c(s1)C(=O)N(C)C)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C22H29F3N4O4S2/c1-13(2)16-11-28(15-7-6-14(12-30)17(10-15)35(5,32)33)8-9-29(16)21-26-19(22(23,24)25)18(34-21)20(31)27(3)4/h6-7,10,13,16,30H,8-9,11-12H2,1-5H3/t16-/m0/s1 KGVFWEDMHGJUPR-INIZCTEOSA-N 304490 (R)-2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-N,N-dimethyl-4-(trifluoromethyl)thiazole-5-carboxamide::US10144715, Compound 17-34 Oxysterols receptor LXR-beta 23.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304490&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883560 381753202 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583864 CC(C)[C@@H]1CN(CCN1c1nc(c(s1)C(N)=O)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C20H25F3N4O4S2/c1-11(2)14-9-26(13-5-4-12(10-28)15(8-13)33(3,30)31)6-7-27(14)19-25-17(20(21,22)23)16(32-19)18(24)29/h4-5,8,11,14,28H,6-7,9-10H2,1-3H3,(H2,24,29)/t14-/m0/s1 VRJNLDNMVIUGAM-AWEZNQCLSA-N 304491 (R)-2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)thiazole-5-carboxamide::US10144715, Compound 17-35 Oxysterols receptor LXR-beta 111 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304491&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883559 381753203 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583866 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@@H](CC2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C26H32F3N3O3S/c1-36(34,35)24-15-21(11-12-22(24)25(30)33)31-13-14-32(23(17-31)19-5-3-2-4-6-19)16-18-7-9-20(10-8-18)26(27,28)29/h2-6,11-12,15,18,20,23H,7-10,13-14,16-17H2,1H3,(H2,30,33)/t18-,20-,23-/m0/s1 AKGAIERBABGAJT-LEDOBFOHSA-N 304492 2-(methylsulfonyl)-4-((R)-3-phenyl-4-(((1r,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 17-36 Oxysterols receptor LXR-beta 1179 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304492&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883561 381753204 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583868 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C26H32F3N3O3S/c1-36(34,35)24-15-21(11-12-22(24)25(30)33)31-13-14-32(23(17-31)19-5-3-2-4-6-19)16-18-7-9-20(10-8-18)26(27,28)29/h2-6,11-12,15,18,20,23H,7-10,13-14,16-17H2,1H3,(H2,30,33)/t18-,20-,23-/m1/s1 AKGAIERBABGAJT-KKLQWCBXSA-N 304493 2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 17-37 Oxysterols receptor LXR-beta 1007 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304493&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883562 381753205 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583870 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C26H32F3N3O3S/c1-36(34,35)24-15-21(11-12-22(24)25(30)33)31-13-14-32(23(17-31)19-5-3-2-4-6-19)16-18-7-9-20(10-8-18)26(27,28)29/h2-6,11-12,15,18,20,23H,7-10,13-14,16-17H2,1H3,(H2,30,33)/t18-,20-,23-/m1/s1 AKGAIERBABGAJT-KKLQWCBXSA-N 304493 2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 17-37 Oxysterols receptor LXR-beta 355 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304493&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883562 381753205 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583872 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C26H32F3N3O3S/c1-36(34,35)24-15-21(11-12-22(24)25(30)33)31-13-14-32(23(17-31)19-5-3-2-4-6-19)16-18-7-9-20(10-8-18)26(27,28)29/h2-6,11-12,15,18,20,23H,7-10,13-14,16-17H2,1H3,(H2,30,33)/t18-,20+,23-/m0/s1 AKGAIERBABGAJT-NOXFTYBFSA-N 304494 2-(methylsulfonyl)-4-((R)-3-phenyl-4-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 17-38 Oxysterols receptor LXR-beta 753 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883561 381753206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583874 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C26H32F3N3O3S/c1-36(34,35)24-15-21(11-12-22(24)25(30)33)31-13-14-32(23(17-31)19-5-3-2-4-6-19)16-18-7-9-20(10-8-18)26(27,28)29/h2-6,11-12,15,18,20,23H,7-10,13-14,16-17H2,1H3,(H2,30,33)/t18-,20+,23-/m0/s1 AKGAIERBABGAJT-NOXFTYBFSA-N 304494 2-(methylsulfonyl)-4-((R)-3-phenyl-4-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 17-38 Oxysterols receptor LXR-beta 561 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304494&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883561 381753206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583875 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C26H32F3N3O3S/c1-36(34,35)24-15-21(11-12-22(24)25(30)33)31-13-14-32(23(17-31)19-5-3-2-4-6-19)16-18-7-9-20(10-8-18)26(27,28)29/h2-6,11-12,15,18,20,23H,7-10,13-14,16-17H2,1H3,(H2,30,33)/t18-,20+,23-/m1/s1 AKGAIERBABGAJT-QMHWCDLVSA-N 304495 2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 17-39 Oxysterols receptor LXR-beta 107 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304495&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883562 381753207 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583877 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C26H32F3N3O3S/c1-36(34,35)24-15-21(11-12-22(24)25(30)33)31-13-14-32(23(17-31)19-5-3-2-4-6-19)16-18-7-9-20(10-8-18)26(27,28)29/h2-6,11-12,15,18,20,23H,7-10,13-14,16-17H2,1H3,(H2,30,33)/t18-,20+,23-/m1/s1 AKGAIERBABGAJT-QMHWCDLVSA-N 304495 2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 17-39 Oxysterols receptor LXR-beta 63.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304495&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883562 381753207 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583879 CC(C)[C@@H]1CN(CCN1c1ccc(cn1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23F4N3O2S/c1-13(2)17-12-26(15-5-6-16(21)18(10-15)30(3,28)29)8-9-27(17)19-7-4-14(11-25-19)20(22,23)24/h4-7,10-11,13,17H,8-9,12H2,1-3H3/t17-/m0/s1 CDVXSTXXLZGAKK-KRWDZBQOSA-N 304360 (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropyl-1-(5-(trifluoromethyl)pyridin-2-yl)piperazine::US10144715, Compound 18-1::US10144715, Compound 7-36 Oxysterols receptor LXR-beta 12.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304360&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554432 381753074 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583881 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m0/s1 FPVIRRAMNBCEDK-KRWDZBQOSA-N 50177015 CHEMBL3814206::US10144715, Compound 19-1 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 67S 5I4V 91827457 346549211 CHEMBL3814206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583883 CC(C)[C@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m1/s1 FPVIRRAMNBCEDK-QGZVFWFLSA-N 50177019 CHEMBL3813863::US10144715, Compound 19-2 Oxysterols receptor LXR-beta 160 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177019&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883505 346549215 CHEMBL3813863 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583885 CC(C)[C@@H]1CN(CCN1c1cncc(c1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23F4N3O2S/c1-13(2)18-12-26(15-4-5-17(21)19(9-15)30(3,28)29)6-7-27(18)16-8-14(10-25-11-16)20(22,23)24/h4-5,8-11,13,18H,6-7,12H2,1-3H3/t18-/m0/s1 HYFGFUVRQMLYAH-SFHVURJKSA-N 304499 (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropyl-1-(5-(trifluoromethyl)pyridin-3-yl)piperazine::US10144715, Compound 20-1 Oxysterols receptor LXR-beta 24.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304499&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872081 381753210 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583887 CC(C)[C@@H]1CN(CCN1c1ccc(cn1)C(C)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H27F2N3O2S/c1-15(2)19-14-25(17-6-5-7-18(12-17)29(4,27)28)10-11-26(19)20-9-8-16(13-24-20)21(3,22)23/h5-9,12-13,15,19H,10-11,14H2,1-4H3/t19-/m0/s1 PFKXVMUDIKLGOG-IBGZPJMESA-N 304500 (R)-1-(5-(1,1-difluoroethyl)pyridin-2-yl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 20-2 Oxysterols receptor LXR-beta 73.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304500&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883568 381753211 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583889 CC(C)[C@@H]1CN(CCN1c1ccc(cn1)C(C)(O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H27F4N3O3S/c1-14(2)18-13-28(16-6-7-17(23)19(11-16)33(4,31)32)9-10-29(18)20-8-5-15(12-27-20)21(3,30)22(24,25)26/h5-8,11-12,14,18,30H,9-10,13H2,1-4H3/t18-,21?/m0/s1 WLDSAWDEZLQZSP-YMXDCFFPSA-N 304501 1,1,1-trifluoro-2-(6-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyridin-3-yl)propan-2-ol::US10144715, Compound 20-3 Oxysterols receptor LXR-beta 52.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304501&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883567 381753212 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583891 CC(C)[C@@H]1CN(CCN1c1ccc(nc1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H26F3N3O3S/c1-14(2)18-12-26(16-5-4-15(13-28)19(10-16)31(3,29)30)8-9-27(18)17-6-7-20(25-11-17)21(22,23)24/h4-7,10-11,14,18,28H,8-9,12-13H2,1-3H3/t18-/m0/s1 UTDAXXUUCUHZOH-SFHVURJKSA-N 304502 (R)-(4-(3-isopropyl-4-(6-(trifluoromethyl)pyridin-3-yl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 20-4 Oxysterols receptor LXR-beta 20.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304502&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883538 381753213 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583893 CC(C)[C@@H]1CN(CCN1c1ncc(cc1N)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O2S/c1-12(2)17-11-27(14-4-5-15(21)18(9-14)31(3,29)30)6-7-28(17)19-16(25)8-13(10-26-19)20(22,23)24/h4-5,8-10,12,17H,6-7,11,25H2,1-3H3/t17-/m0/s1 NIRYIUZPINDTNT-KRWDZBQOSA-N 304503 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyridin-3-amine::US10144715, Compound 21-1 Oxysterols receptor LXR-beta 31.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304503&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883451 381753214 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583894 CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(n1)C1CC1)c1ccc(F)c(c1Cl)S(C)(=O)=O InChI=1S/C21H25Cl2FN4O2S/c1-12(2)17-11-27(16-7-6-15(24)20(18(16)23)31(3,29)30)8-9-28(17)21-25-10-14(22)19(26-21)13-4-5-13/h6-7,10,12-13,17H,4-5,8-9,11H2,1-3H3/t17-/m0/s1 TYKVZSRKEXNMHT-KRWDZBQOSA-N 304504 (R)-5-chloro-2-(4-(2-chloro-4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-cyclopropylpyrimidine::US10144715, Compound 22-2 Oxysterols receptor LXR-beta 172 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304504&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883510 381753215 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583897 CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(n1)C(C)(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H30ClFN4O2S/c1-14(2)18-13-27(15-7-8-17(24)19(11-15)31(6,29)30)9-10-28(18)21-25-12-16(23)20(26-21)22(3,4)5/h7-8,11-12,14,18H,9-10,13H2,1-6H3/t18-/m0/s1 VTSLTFRMYLXJLX-SFHVURJKSA-N 304505 (R)-5-chloro-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 22-3 Oxysterols receptor LXR-beta 1.000 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304505&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 130304943 381753216 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583900 CC(C)Cc1cc(nc(n1)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C23H30F4N4O2S/c1-14(2)10-16-11-21(23(25,26)27)29-22(28-16)31-9-8-30(13-19(31)15(3)4)17-6-7-18(24)20(12-17)34(5,32)33/h6-7,11-12,14-15,19H,8-10,13H2,1-5H3/t19-/m0/s1 MCNANSBMKLEYHJ-IBGZPJMESA-N 304507 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-isopropoxy-6-(trifluoromethyl)pyrimidine::US10144715, Compound 23-1 Oxysterols receptor LXR-beta 212 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304507&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554532 381753218 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583902 CC(C)Oc1cc(nc(n1)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C22H28F4N4O3S/c1-13(2)17-12-29(15-6-7-16(23)18(10-15)34(5,31)32)8-9-30(17)21-27-19(22(24,25)26)11-20(28-21)33-14(3)4/h6-7,10-11,13-14,17H,8-9,12H2,1-5H3/t17-/m0/s1 CIEXBPBDMWXPTC-KRWDZBQOSA-N 304508 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-ol::US10144715, Compound 24-1 Oxysterols receptor LXR-beta 944 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304508&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883494 381753219 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583904 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(F)(F)F)C(C)(C)C#N)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C25H32F3N5O3S/c1-16(2)20-14-32(18-7-6-17(8-11-34)21(12-18)37(5,35)36)9-10-33(20)23-30-13-19(24(3,4)15-29)22(31-23)25(26,27)28/h6-7,12-13,16,20,34H,8-11,14H2,1-5H3/t20-/m0/s1 NEGSIYPKPKVQAA-FQEVSTJZSA-N 304509 (R)-2-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)-2-methylpropanenitrile::US10144715, Compound 25-1 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304509&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554533 381753220 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583906 CC(C)[C@@H]1CN(CCN1c1nc(c(s1)C(C)(C)O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H27F4N3O3S2/c1-12(2)15-11-27(13-6-7-14(22)16(10-13)33(5,30)31)8-9-28(15)19-26-17(21(23,24)25)18(32-19)20(3,4)29/h6-7,10,12,15,29H,8-9,11H2,1-5H3/t15-/m0/s1 CDLANIGSVPOVRJ-HNNXBMFYSA-N 304510 (R)-2-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)thiazol-5-yl)propan-2-ol::US10144715, Compound 26-1 Oxysterols receptor LXR-beta 5.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304510&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883571 381753221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583908 CC(C)[C@@H]1CN(CCN1c1nc(c(o1)C(C)(C)O)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C22H30F3N3O5S/c1-13(2)16-11-27(15-7-6-14(12-29)17(10-15)34(5,31)32)8-9-28(16)20-26-18(22(23,24)25)19(33-20)21(3,4)30/h6-7,10,13,16,29-30H,8-9,11-12H2,1-5H3/t16-/m0/s1 ZKMARVGQZGTVHR-INIZCTEOSA-N 304511 (R)-2-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)oxazol-5-yl)propan-2-ol::US10144715, Compound 26-2 Oxysterols receptor LXR-beta 72.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304511&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883541 381753222 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583910 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nc(C)cs2)c(c1)S(C)(=O)=O InChI=1S/C24H28F3N5O3S2/c1-14(2)19-11-31(7-8-32(19)23-28-10-16(12-33)21(30-23)24(25,26)27)17-5-6-18(20(9-17)37(4,34)35)22-29-15(3)13-36-22/h5-6,9-10,13-14,19,33H,7-8,11-12H2,1-4H3/t19-/m0/s1 IQRSIUBKAADOQA-IBGZPJMESA-N 304512 (R)-2-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)thiazol-5-yl)propan-2-ol::US10144715, Compound 27-1::US10144715, Compound 28-1 Oxysterols receptor LXR-beta 10.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304512&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883535 381753223 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583912 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(-c2nc(C)cs2)c(c1)S(C)(=O)=O InChI=1S/C24H28F3N5O3S2/c1-14(2)19-11-31(7-8-32(19)23-28-10-16(12-33)21(30-23)24(25,26)27)17-5-6-18(20(9-17)37(4,34)35)22-29-15(3)13-36-22/h5-6,9-10,13-14,19,33H,7-8,11-12H2,1-4H3/t19-/m0/s1 IQRSIUBKAADOQA-IBGZPJMESA-N 304512 (R)-2-(2-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)thiazol-5-yl)propan-2-ol::US10144715, Compound 27-1::US10144715, Compound 28-1 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304512&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883535 381753223 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583914 CC(C)[C@@H]1CN(CCN1c1ncc(B2OC(C)(C)C(C)(C)O2)c(n1)C(F)(F)F)C(=O)OCc1ccccc1 InChI=1S/C26H34BF3N4O4/c1-17(2)20-15-33(23(35)36-16-18-10-8-7-9-11-18)12-13-34(20)22-31-14-19(21(32-22)26(28,29)30)27-37-24(3,4)25(5,6)38-27/h7-11,14,17,20H,12-13,15-16H2,1-6H3/t20-/m0/s1 VCNKBGCNOUBXAD-FQEVSTJZSA-N 304514 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-methoxy-4-(trifluoromethyl)pyrimidine::US10144715, Compound 29-1 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304514&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554534 381753224 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583916 CC(C)[C@@H]1CN(CCN1c1ncc(O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O3S/c1-11(2)14-10-26(12-4-5-13(20)16(8-12)31(3,29)30)6-7-27(14)18-24-9-15(28)17(25-18)19(21,22)23/h4-5,8-9,11,14,28H,6-7,10H2,1-3H3/t14-/m0/s1 XLYCLDVZZOFLRE-AWEZNQCLSA-N 304515 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-ol::US10144715, Compound 30-1 Oxysterols receptor LXR-beta 24.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304515&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883493 381753225 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583918 CC(C)[C@@H]1CN(CCN1c1ncc(Cc2ccc(cc2)C(C)(C)O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C29H34F4N4O3S/c1-18(2)24-17-36(22-10-11-23(30)25(15-22)41(5,39)40)12-13-37(24)27-34-16-20(26(35-27)29(31,32)33)14-19-6-8-21(9-7-19)28(3,4)38/h6-11,15-16,18,24,38H,12-14,17H2,1-5H3/t24-/m0/s1 NRUNDIXYUOKLPO-DEOSSOPVSA-N 304516 (R)-2-(4-((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 31-1 Oxysterols receptor LXR-beta 18.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304516&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883461 381753226 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583920 CC(C)[C@@H]1CN(CCN1c1ncc(Cc2ccc(OC=O)cc2)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C27H28F4N4O4S/c1-17(2)23-15-34(20-6-9-22(28)24(13-20)40(3,37)38)10-11-35(23)26-32-14-19(25(33-26)27(29,30)31)12-18-4-7-21(8-5-18)39-16-36/h4-9,13-14,16-17,23H,10-12,15H2,1-3H3/t23-/m0/s1 CRBFBKFQHKHSNV-QHCPKHFHSA-N 304517 (R)-4-((2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methyl)benzoic acid::US10144715, Compound 32-1 Oxysterols receptor LXR-beta 22.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304517&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554535 381753227 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583922 COc1cc(ccn1)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H26FN3O3S/c1-14(2)18-13-23(15-5-6-17(21)19(11-15)28(4,25)26)9-10-24(18)16-7-8-22-20(12-16)27-3/h5-8,11-12,14,18H,9-10,13H2,1-4H3/t18-/m0/s1 OPEYIXLYURKODO-SFHVURJKSA-N 304518 (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropyl-1-(2-methoxypyridin-4-yl)piperazine::US10144715, Compound 33-1 Oxysterols receptor LXR-beta 114 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304518&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872032 381753228 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583924 COc1cc(ccn1)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H26FN3O3S/c1-14(2)18-13-23(15-5-6-17(21)19(11-15)28(4,25)26)9-10-24(18)16-7-8-22-20(12-16)27-3/h5-8,11-12,14,18H,9-10,13H2,1-4H3/t18-/m0/s1 OPEYIXLYURKODO-SFHVURJKSA-N 304518 (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropyl-1-(2-methoxypyridin-4-yl)piperazine::US10144715, Compound 33-1 Oxysterols receptor LXR-beta 16.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304518&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872032 381753228 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583926 CC(C)(O)CC1CN(CCN1c1ccc(cn1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H25F4N3O3S/c1-20(2,29)11-16-13-27(15-5-6-17(22)18(10-15)32(3,30)31)8-9-28(16)19-7-4-14(12-26-19)21(23,24)25/h4-7,10,12,16,29H,8-9,11,13H2,1-3H3 JDLRYODDTOIAFI-UHFFFAOYSA-N 304519 1-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-1-(5-(trifluoromethyl)pyridin-2-yl)piperazin-2-yl)-2-methylpropan-2-ol::US10144715, Compound 34-1 Oxysterols receptor LXR-beta 151 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304519&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872016 381753229 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583928 CC(C)(F)CC1CN(CCN1c1ccc(cn1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H24F5N3O2S/c1-20(2,23)11-16-13-28(15-5-6-17(22)18(10-15)32(3,30)31)8-9-29(16)19-7-4-14(12-27-19)21(24,25)26/h4-7,10,12,16H,8-9,11,13H2,1-3H3 TYSRYKHSEFCGPN-UHFFFAOYSA-N 304520 2-(2-fluoro-2-methylpropyl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-1-(5-(trifluoromethyl)pyridin-2-yl)piperazine::US10144715, Compound 35-1 Oxysterols receptor LXR-beta 38.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304520&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872098 381753230 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583930 CC(C)[C@@H]1CN(CCN1c1ncc(c(Cl)n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H21ClF4N4O2S/c1-11(2)15-10-27(12-4-5-14(21)16(8-12)31(3,29)30)6-7-28(15)18-25-9-13(17(20)26-18)19(22,23)24/h4-5,8-9,11,15H,6-7,10H2,1-3H3/t15-/m0/s1 KZCSVWPMPDGZGU-HNNXBMFYSA-N 304521 (R)-4-chloro-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyrimidine::US10144715, Compound 36-1::US10144715, Compound 43-1 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304521&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883464 381753231 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583931 CC(C)[C@@H]1CN(CCN1c1ncc(c(C)n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O2S/c1-12(2)17-11-27(14-5-6-16(21)18(9-14)31(4,29)30)7-8-28(17)19-25-10-15(13(3)26-19)20(22,23)24/h5-6,9-10,12,17H,7-8,11H2,1-4H3/t17-/m0/s1 DXEPMKDNFAOHFI-KRWDZBQOSA-N 304522 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methyl-5-(trifluoromethyl)pyrimidine::US10144715, Compound 37-1 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304522&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883496 381753232 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583933 CC(C)[C@@H]1CN(CCN1c1ccc(c(C)n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H26F3N3O2S/c1-14(2)19-13-26(16-6-5-7-17(12-16)30(4,28)29)10-11-27(19)20-9-8-18(15(3)25-20)21(22,23)24/h5-9,12,14,19H,10-11,13H2,1-4H3/t19-/m0/s1 NXAQUWGSGCUYGJ-IBGZPJMESA-N 304523 (R)-2-isopropyl-1-(6-methyl-5-(trifluoromethyl)pyridin-2-yl)-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 37-2 Oxysterols receptor LXR-beta 2.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304523&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883477 381753233 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583935 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C#N)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H21F4N5O2S/c1-12(2)17-11-28(13-4-5-15(21)18(8-13)32(3,30)31)6-7-29(17)19-26-10-14(20(22,23)24)16(9-25)27-19/h4-5,8,10,12,17H,6-7,11H2,1-3H3/t17-/m0/s1 GVRPVYDNQAVCMD-KRWDZBQOSA-N 304524 1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyrimidin-4-yl)ethan-1-ol::US10144715, Compound 38-1 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304524&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883478 381753234 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583937 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(C)(C)O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28F4N4O3S/c1-13(2)17-12-29(14-6-7-16(23)18(10-14)34(5,32)33)8-9-30(17)20-27-11-15(22(24,25)26)19(28-20)21(3,4)31/h6-7,10-11,13,17,31H,8-9,12H2,1-5H3/t17-/m0/s1 XTWZRTUIFQOMNH-KRWDZBQOSA-N 304525 (R)-2-(2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyrimidin-4-yl)propan-2-ol::US10144715, Compound 39-1 Oxysterols receptor LXR-beta 2.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304525&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883569 381753235 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583938 CC(C)[C@@H]1CN(CCN1c1ncc(Br)c(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H22BrF3N4O2S/c1-12(2)16-11-26(13-5-4-6-14(9-13)30(3,28)29)7-8-27(16)18-24-10-15(20)17(25-18)19(21,22)23/h4-6,9-10,12,16H,7-8,11H2,1-3H3/t16-/m0/s1 MWAVZHXRLCYQCL-INIZCTEOSA-N 304526 (R)-5-cyclopropyl-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 40-1 Oxysterols receptor LXR-beta 1.000 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304526&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554536 381753236 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583940 CC(C)[C@@H]1CN(CCN1c1ccc(C)c(n1)C1CC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H31N3O2S/c1-16(2)21-15-25(19-6-5-7-20(14-19)29(4,27)28)12-13-26(21)22-11-8-17(3)23(24-22)18-9-10-18/h5-8,11,14,16,18,21H,9-10,12-13,15H2,1-4H3/t21-/m0/s1 SYMWSPSNNOTRBN-NRFANRHFSA-N 304527 (R)-1-(6-cyclopropyl-5-methylpyridin-2-yl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 40-2 Oxysterols receptor LXR-beta 14.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304527&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554537 381753237 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583942 CC(C)[C@@H]1CN(CCN1c1nc(ccc1C)C1CC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H31N3O2S/c1-16(2)22-15-25(19-6-5-7-20(14-19)29(4,27)28)12-13-26(22)23-17(3)8-11-21(24-23)18-9-10-18/h5-8,11,14,16,18,22H,9-10,12-13,15H2,1-4H3/t22-/m0/s1 FJLDUPMMOBCQAG-QFIPXVFZSA-N 304528 (R)-1-(6-cyclopropyl-3-methylpyridin-2-yl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 40-3 Oxysterols receptor LXR-beta 61.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304528&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554538 381753238 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583944 CC(C)[C@@H]1CN(CCN1c1ccc(c(n1)C1CC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H28F3N3O2S/c1-15(2)20-14-28(17-5-4-6-18(13-17)32(3,30)31)11-12-29(20)21-10-9-19(23(24,25)26)22(27-21)16-7-8-16/h4-6,9-10,13,15-16,20H,7-8,11-12,14H2,1-3H3/t20-/m0/s1 NSWRBHFZGBXSGU-FQEVSTJZSA-N 304529 (R)-1-(6-cyclopropyl-5-(trifluoromethyl)pyridin-2-yl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 40-4 Oxysterols receptor LXR-beta 7.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304529&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554539 381753239 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583946 CC(C)[C@@H]1CN(CCN1c1ncc(cn1)C(O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O3S/c1-12(2)16-11-27(14-4-5-15(21)17(8-14)32(3,30)31)6-7-28(16)19-25-9-13(10-26-19)18(29)20(22,23)24/h4-5,8-10,12,16,18,29H,6-7,11H2,1-3H3/t16-,18?/m0/s1 QHNIUHGGWGTKNW-ATNAJCNCSA-N 304530 2,2,2-trifluoro-1-(2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyrimidin-5-yl)ethan-1-ol::US10144715, Compound 41-1 Oxysterols receptor LXR-beta 92.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304530&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872129 381753240 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583948 COC(c1cnc(nc1)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C21H26F4N4O3S/c1-13(2)17-12-28(15-5-6-16(22)18(9-15)33(4,30)31)7-8-29(17)20-26-10-14(11-27-20)19(32-3)21(23,24)25/h5-6,9-11,13,17,19H,7-8,12H2,1-4H3/t17-,19?/m0/s1 OBXLHEARDPFUMN-KKFHFHRHSA-N 304531 2-((R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(2,2,2-trifluoro-1-methoxyethyl)pyrimidine::US10144715, Compound 42-1 Oxysterols receptor LXR-beta 33.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304531&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872138 381753241 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583950 CC(C)[C@@H]1CN(CCN1c1ncc(c(Cl)n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H21ClF4N4O2S/c1-11(2)15-10-27(12-4-5-14(21)16(8-12)31(3,29)30)6-7-28(15)18-25-9-13(17(20)26-18)19(22,23)24/h4-5,8-9,11,15H,6-7,10H2,1-3H3/t15-/m0/s1 KZCSVWPMPDGZGU-HNNXBMFYSA-N 304521 (R)-4-chloro-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyrimidine::US10144715, Compound 36-1::US10144715, Compound 43-1 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304521&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883464 381753231 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583952 CC(C)[C@@H]1CN(CCN1c1ccnc(OC(F)F)c1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F3N3O3S/c1-13(2)17-12-25(14-4-5-16(21)18(10-14)30(3,27)28)8-9-26(17)15-6-7-24-19(11-15)29-20(22)23/h4-7,10-11,13,17,20H,8-9,12H2,1-3H3/t17-/m0/s1 CCZANINLKOMNJX-KRWDZBQOSA-N 304533 (R)-1-(2-(difluoromethoxy)pyridin-4-yl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine::US10144715, Compound 44-1 Oxysterols receptor LXR-beta 7.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304533&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872109 381753242 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583954 CC(C)[C@@H]1CN(CCN1c1nccc(OC(F)F)n1)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H24F2N4O3S/c1-13(2)16-12-24(14-5-4-6-15(11-14)29(3,26)27)9-10-25(16)19-22-8-7-17(23-19)28-18(20)21/h4-8,11,13,16,18H,9-10,12H2,1-3H3/t16-/m0/s1 YBSIHBWDBRSCLD-INIZCTEOSA-N 304534 (R)-4-(difluoromethoxy)-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine::US10144715, Compound 44-2 Oxysterols receptor LXR-beta 35.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304534&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883499 381753243 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583956 CC(C)[C@@H]1CN(CCN1c1nccc(OCC(F)(F)F)n1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O3S/c1-13(2)16-11-27(14-4-5-15(21)17(10-14)32(3,29)30)8-9-28(16)19-25-7-6-18(26-19)31-12-20(22,23)24/h4-7,10,13,16H,8-9,11-12H2,1-3H3/t16-/m0/s1 DYLGLRCPXIXIET-INIZCTEOSA-N 304535 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(2,2,2-trifluoroethoxy)pyrimidine::US10144715, Compound 44-3 Oxysterols receptor LXR-beta 67.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304535&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883498 381753244 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583958 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@@H](Cc2ccccc2)C1 InChI=1S/C26H26ClF3N2O2S/c1-35(33,34)23-9-5-8-21(16-23)32-13-12-31(22(18-32)14-19-6-3-2-4-7-19)17-20-10-11-24(25(27)15-20)26(28,29)30/h2-11,15-16,22H,12-14,17-18H2,1H3/t22-/m0/s1 HBGAEWRRFPYOSC-QFIPXVFZSA-N 304536 (S)-2-benzyl-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)piperazine::BDBM304568::US10144715, Compound 45-1 Oxysterols receptor LXR-beta 68.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304536&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872040 381753245 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583960 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H24ClF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3 SYWHAWSOSMSFBS-UHFFFAOYSA-N 304537 1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-1 Oxysterols receptor LXR-beta 156 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304537&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872132 381753246 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583962 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C25H24ClF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m0/s1 SYWHAWSOSMSFBS-DEOSSOPVSA-N 304538 (R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-2 Oxysterols receptor LXR-beta 1048 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304538&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872080 381753247 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583964 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C25H24ClF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m1/s1 SYWHAWSOSMSFBS-XMMPIXPASA-N 304539 (S)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-3 Oxysterols receptor LXR-beta 15.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304539&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872094 381753248 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583966 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C25H24ClF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m1/s1 SYWHAWSOSMSFBS-XMMPIXPASA-N 304539 (S)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-3 Oxysterols receptor LXR-beta 86.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304539&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872094 381753248 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583968 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccccc2)C(C1)c1ccccc1 InChI=1S/C24H26N2O2S/c1-29(27,28)23-14-8-13-22(17-23)25-15-16-26(18-20-9-4-2-5-10-20)24(19-25)21-11-6-3-7-12-21/h2-14,17,24H,15-16,18-19H2,1H3 JJJWPNKCBQSHHN-UHFFFAOYSA-N 304301 BDBM304540::US10144715, Compound 1-14::benzyl 4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304301&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554389 381753016 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583970 Cc1ccc(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C25H28N2O2S/c1-20-11-13-21(14-12-20)18-27-16-15-26(19-25(27)22-7-4-3-5-8-22)23-9-6-10-24(17-23)30(2,28)29/h3-14,17,25H,15-16,18-19H2,1-2H3/t25-/m0/s1 JYFOULIZQPAJEL-VWLOTQADSA-N 304541 (R)-1-(4-methylbenzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-5 Oxysterols receptor LXR-beta 7159 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304541&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554540 381753250 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583972 Cc1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C25H28N2O2S/c1-20-11-13-21(14-12-20)18-27-16-15-26(19-25(27)22-7-4-3-5-8-22)23-9-6-10-24(17-23)30(2,28)29/h3-14,17,25H,15-16,18-19H2,1-2H3/t25-/m1/s1 JYFOULIZQPAJEL-RUZDIDTESA-N 304542 (S)-1-(4-methylbenzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-6 Oxysterols receptor LXR-beta 63.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304542&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554541 381753251 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583974 Cc1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C25H28N2O2S/c1-20-11-13-21(14-12-20)18-27-16-15-26(19-25(27)22-7-4-3-5-8-22)23-9-6-10-24(17-23)30(2,28)29/h3-14,17,25H,15-16,18-19H2,1-2H3/t25-/m1/s1 JYFOULIZQPAJEL-RUZDIDTESA-N 304542 (S)-1-(4-methylbenzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-6 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304542&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554541 381753251 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583976 CC(C)c1ccc(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C27H32N2O2S/c1-21(2)23-14-12-22(13-15-23)19-29-17-16-28(20-27(29)24-8-5-4-6-9-24)25-10-7-11-26(18-25)32(3,30)31/h4-15,18,21,27H,16-17,19-20H2,1-3H3/t27-/m0/s1 JJGDWETYUNWORM-MHZLTWQESA-N 304543 (R)-1-(4-isopropylbenzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-7 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304543&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554542 381753252 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583978 CC(C)c1ccc(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C27H32N2O2S/c1-21(2)23-14-12-22(13-15-23)19-29-17-16-28(20-27(29)24-8-5-4-6-9-24)25-10-7-11-26(18-25)32(3,30)31/h4-15,18,21,27H,16-17,19-20H2,1-3H3/t27-/m0/s1 JJGDWETYUNWORM-MHZLTWQESA-N 304543 (R)-1-(4-isopropylbenzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-7 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304543&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554542 381753252 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583980 CC(C)c1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C27H32N2O2S/c1-21(2)23-14-12-22(13-15-23)19-29-17-16-28(20-27(29)24-8-5-4-6-9-24)25-10-7-11-26(18-25)32(3,30)31/h4-15,18,21,27H,16-17,19-20H2,1-3H3/t27-/m1/s1 JJGDWETYUNWORM-HHHXNRCGSA-N 304544 (S)-1-(4-isopropylbenzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-8 Oxysterols receptor LXR-beta 227 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304544&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554543 381753253 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583982 CC(C)c1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1 InChI=1S/C27H32N2O2S/c1-21(2)23-14-12-22(13-15-23)19-29-17-16-28(20-27(29)24-8-5-4-6-9-24)25-10-7-11-26(18-25)32(3,30)31/h4-15,18,21,27H,16-17,19-20H2,1-3H3/t27-/m1/s1 JJGDWETYUNWORM-HHHXNRCGSA-N 304544 (S)-1-(4-isopropylbenzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-8 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304544&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554543 381753253 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583984 CC(C)[C@H]1CN(CCN1Cc1ccc(cc1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C23H26F3N3O2S/c1-16(2)21-15-28(20-9-6-18(13-27)22(12-20)32(3,30)31)10-11-29(21)14-17-4-7-19(8-5-17)23(24,25)26/h4-9,12,16,21H,10-11,14-15H2,1-3H3/t21-/m1/s1 WNKXQZJSDKGXOR-OAQYLSRUSA-N 304545 (S)-4-(3-isopropyl-4-(4-(trifluoromethyl)benzyl)piperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 46-9 Oxysterols receptor LXR-beta 231 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304545&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554544 381753254 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583986 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(OC(F)F)cc2)[C@@H](C1)c1ccccc1 InChI=1S/C25H26F2N2O3S/c1-33(30,31)23-9-5-8-21(16-23)28-14-15-29(24(18-28)20-6-3-2-4-7-20)17-19-10-12-22(13-11-19)32-25(26)27/h2-13,16,24-25H,14-15,17-18H2,1H3/t24-/m0/s1 UBVQCIPLRSNTSM-DEOSSOPVSA-N 304546 (R)-1-(4-(difluoromethoxy)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-10 Oxysterols receptor LXR-beta 24999 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304546&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554545 381753255 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583988 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(OC(F)F)cc2)[C@H](C1)c1ccccc1 InChI=1S/C25H26F2N2O3S/c1-33(30,31)23-9-5-8-21(16-23)28-14-15-29(24(18-28)20-6-3-2-4-7-20)17-19-10-12-22(13-11-19)32-25(26)27/h2-13,16,24-25H,14-15,17-18H2,1H3/t24-/m1/s1 UBVQCIPLRSNTSM-XMMPIXPASA-N 304547 (S)-1-(4-(difluoromethoxy)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-11 Oxysterols receptor LXR-beta 445 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304547&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554546 381753256 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583990 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(OC(F)F)cc2)[C@H](C1)c1ccccc1 InChI=1S/C25H26F2N2O3S/c1-33(30,31)23-9-5-8-21(16-23)28-14-15-29(24(18-28)20-6-3-2-4-7-20)17-19-10-12-22(13-11-19)32-25(26)27/h2-13,16,24-25H,14-15,17-18H2,1H3/t24-/m1/s1 UBVQCIPLRSNTSM-XMMPIXPASA-N 304547 (S)-1-(4-(difluoromethoxy)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-11 Oxysterols receptor LXR-beta 600 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304547&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554546 381753256 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583992 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccccc2C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H25F3N2O2S/c1-33(31,32)22-12-7-11-21(16-22)29-14-15-30(24(18-29)19-8-3-2-4-9-19)17-20-10-5-6-13-23(20)25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3 QXMKNSZDBQBKKI-UHFFFAOYSA-N 304548 4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(2-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-12 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304548&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554547 381753257 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583994 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2cccc(c2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H25F3N2O2S/c1-33(31,32)23-12-6-11-22(16-23)29-13-14-30(24(18-29)20-8-3-2-4-9-20)17-19-7-5-10-21(15-19)25(26,27)28/h2-12,15-16,24H,13-14,17-18H2,1H3 BNJALVDIYAYGBZ-UHFFFAOYSA-N 304549 4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(3-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-13 Oxysterols receptor LXR-beta 547 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304549&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554548 381753258 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583996 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cc2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C25H25F3N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)20-6-3-2-4-7-20)17-19-10-12-21(13-11-19)25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3/t24-/m0/s1 JWDYOAJOJBVJKK-DEOSSOPVSA-N 304550 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-14 Oxysterols receptor LXR-beta 2742 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304550&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554549 381753259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583997 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cc2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C25H25F3N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)20-6-3-2-4-7-20)17-19-10-12-21(13-11-19)25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3/t24-/m1/s1 JWDYOAJOJBVJKK-XMMPIXPASA-N 304551 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-15 Oxysterols receptor LXR-beta 158 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304551&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554550 381753260 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583999 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cc2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C25H25F3N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)20-6-3-2-4-7-20)17-19-10-12-21(13-11-19)25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3/t24-/m1/s1 JWDYOAJOJBVJKK-XMMPIXPASA-N 304551 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-15 Oxysterols receptor LXR-beta 418 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304551&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554550 381753260 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584000 CC(N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O)c1ccc(cc1)C(F)(F)F InChI=1S/C26H27F3N2O2S/c1-19(20-11-13-22(14-12-20)26(27,28)29)31-16-15-30(18-25(31)21-7-4-3-5-8-21)23-9-6-10-24(17-23)34(2,32)33/h3-14,17,19,25H,15-16,18H2,1-2H3/t19?,25-/m1/s1 DJPSHUCKIYCLKV-OPEAARRCSA-N 304552 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1-(4-(trifluoromethyl)phenyl)ethyl)piperazine::US10144715, Compound 46-16::US10144715, Compound 46-18 Oxysterols receptor LXR-beta 503 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304552&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554551 381753261 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584002 CC(N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O)c1ccc(cc1)C(F)(F)F InChI=1S/C26H27F3N2O2S/c1-19(20-11-13-22(14-12-20)26(27,28)29)31-16-15-30(18-25(31)21-7-4-3-5-8-21)23-9-6-10-24(17-23)34(2,32)33/h3-14,17,19,25H,15-16,18H2,1-2H3/t19?,25-/m0/s1 DJPSHUCKIYCLKV-BIAFCPFJSA-N 304553 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1-(4-(trifluoromethyl)phenyl)ethyl)piperazine::US10144715, Compound 46-17::US10144715, Compound 46-19 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304553&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554552 381753262 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584003 CC(N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O)c1ccc(cc1)C(F)(F)F InChI=1S/C26H27F3N2O2S/c1-19(20-11-13-22(14-12-20)26(27,28)29)31-16-15-30(18-25(31)21-7-4-3-5-8-21)23-9-6-10-24(17-23)34(2,32)33/h3-14,17,19,25H,15-16,18H2,1-2H3/t19?,25-/m1/s1 DJPSHUCKIYCLKV-OPEAARRCSA-N 304552 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1-(4-(trifluoromethyl)phenyl)ethyl)piperazine::US10144715, Compound 46-16::US10144715, Compound 46-18 Oxysterols receptor LXR-beta 35.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304552&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554551 381753261 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584005 CC(N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O)c1ccc(cc1)C(F)(F)F InChI=1S/C26H27F3N2O2S/c1-19(20-11-13-22(14-12-20)26(27,28)29)31-16-15-30(18-25(31)21-7-4-3-5-8-21)23-9-6-10-24(17-23)34(2,32)33/h3-14,17,19,25H,15-16,18H2,1-2H3/t19?,25-/m0/s1 DJPSHUCKIYCLKV-BIAFCPFJSA-N 304553 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1-(4-(trifluoromethyl)phenyl)ethyl)piperazine::US10144715, Compound 46-17::US10144715, Compound 46-19 Oxysterols receptor LXR-beta 1903 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304553&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554552 381753262 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584007 C[C@@]1(CN(CCN1Cc1ccc(cc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)c1ccccc1 InChI=1S/C26H27F3N2O2S/c1-25(21-7-4-3-5-8-21)19-30(23-9-6-10-24(17-23)34(2,32)33)15-16-31(25)18-20-11-13-22(14-12-20)26(27,28)29/h3-14,17H,15-16,18-19H2,1-2H3/t25-/m1/s1 JCHCJNMYNQONJW-RUZDIDTESA-N 304556 (R)-2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-20 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304556&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554553 381753263 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584008 C[C@]1(CN(CCN1Cc1ccc(cc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)c1ccccc1 InChI=1S/C26H27F3N2O2S/c1-25(21-7-4-3-5-8-21)19-30(23-9-6-10-24(17-23)34(2,32)33)15-16-31(25)18-20-11-13-22(14-12-20)26(27,28)29/h3-14,17H,15-16,18-19H2,1-2H3/t25-/m0/s1 JCHCJNMYNQONJW-VWLOTQADSA-N 304557 (S)-2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-21 Oxysterols receptor LXR-beta 85.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304557&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554554 381753264 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584010 C[C@]1(CN(CCN1Cc1ccc(cc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)c1ccccc1 InChI=1S/C26H27F3N2O2S/c1-25(21-7-4-3-5-8-21)19-30(23-9-6-10-24(17-23)34(2,32)33)15-16-31(25)18-20-11-13-22(14-12-20)26(27,28)29/h3-14,17H,15-16,18-19H2,1-2H3/t25-/m0/s1 JCHCJNMYNQONJW-VWLOTQADSA-N 304557 (S)-2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-21 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304557&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554554 381753264 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584012 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(OC(F)(F)F)cc2)[C@@H](C1)c1ccccc1 InChI=1S/C25H25F3N2O3S/c1-34(31,32)23-9-5-8-21(16-23)29-14-15-30(24(18-29)20-6-3-2-4-7-20)17-19-10-12-22(13-11-19)33-25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3/t24-/m0/s1 OFJPMEOQNCZLEA-DEOSSOPVSA-N 304558 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethoxy)benzyl)piperazine::US10144715, Compound 46-22 Oxysterols receptor LXR-beta 1273 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304558&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554555 381753265 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584014 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(OC(F)(F)F)cc2)[C@H](C1)c1ccccc1 InChI=1S/C25H25F3N2O3S/c1-34(31,32)23-9-5-8-21(16-23)29-14-15-30(24(18-29)20-6-3-2-4-7-20)17-19-10-12-22(13-11-19)33-25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3/t24-/m1/s1 OFJPMEOQNCZLEA-XMMPIXPASA-N 304559 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethoxy)benzyl)piperazine::US10144715, Compound 46-23 Oxysterols receptor LXR-beta 112 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304559&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554556 381753266 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584016 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(OC(F)(F)F)cc2)[C@H](C1)c1ccccc1 InChI=1S/C25H25F3N2O3S/c1-34(31,32)23-9-5-8-21(16-23)29-14-15-30(24(18-29)20-6-3-2-4-7-20)17-19-10-12-22(13-11-19)33-25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3/t24-/m1/s1 OFJPMEOQNCZLEA-XMMPIXPASA-N 304559 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethoxy)benzyl)piperazine::US10144715, Compound 46-23 Oxysterols receptor LXR-beta 710 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304559&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554556 381753266 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584017 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cc2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C25H24F4N2O2S/c1-34(32,33)23-4-2-3-22(15-23)30-13-14-31(24(17-30)19-7-11-21(26)12-8-19)16-18-5-9-20(10-6-18)25(27,28)29/h2-12,15,24H,13-14,16-17H2,1H3/t24-/m1/s1 IWPHWMCUCCRQQY-XMMPIXPASA-N 304560 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-24 Oxysterols receptor LXR-beta 359 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304560&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554557 381753267 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584019 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cc2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C25H24F4N2O2S/c1-34(32,33)23-4-2-3-22(15-23)30-13-14-31(24(17-30)19-7-11-21(26)12-8-19)16-18-5-9-20(10-6-18)25(27,28)29/h2-12,15,24H,13-14,16-17H2,1H3/t24-/m1/s1 IWPHWMCUCCRQQY-XMMPIXPASA-N 304560 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-24 Oxysterols receptor LXR-beta 347 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304560&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554557 381753267 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584021 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(F)c2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C25H24F4N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m0/s1 IWEGTTXPZDEMNE-DEOSSOPVSA-N 304561 (R)-1-(3-fluoro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-25 Oxysterols receptor LXR-beta 17972 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304561&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554558 381753268 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584022 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(F)c2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C25H24F4N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m1/s1 IWEGTTXPZDEMNE-XMMPIXPASA-N 304562 (S)-1-(3-fluoro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-26 Oxysterols receptor LXR-beta 58.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304562&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554559 381753269 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584024 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(F)c2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C25H24F4N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m1/s1 IWEGTTXPZDEMNE-XMMPIXPASA-N 304562 (S)-1-(3-fluoro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-26 Oxysterols receptor LXR-beta 411 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304562&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554559 381753269 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584026 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(F)c2)C(F)(F)F)[C@@H](C1)C1CCCCC1 InChI=1S/C25H30F4N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h5,8-11,14-15,19,24H,2-4,6-7,12-13,16-17H2,1H3/t24-/m0/s1 WLBZPKODHAZJLW-DEOSSOPVSA-N 304563 1-(3-chloro-4-(trifluoromethyl)benzyl)-2-cyclohexyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 46-27 Oxysterols receptor LXR-beta 28.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304563&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554560 381753270 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584028 CC(O)(c1ccc(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1)C(F)(F)F InChI=1S/C27H29F3N2O3S/c1-26(33,27(28,29)30)22-13-11-20(12-14-22)18-32-16-15-31(19-25(32)21-7-4-3-5-8-21)23-9-6-10-24(17-23)36(2,34)35/h3-14,17,25,33H,15-16,18-19H2,1-2H3/t25-,26?/m0/s1 XCQRRLCJFNEFKV-PMCHYTPCSA-N 304564 (S)-1,1,1-trifluoro-2-(4-(((S)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 46-28::US10144715, Compound 46-31 Oxysterols receptor LXR-beta 501 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304564&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554561 381753271 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584030 CC(O)(c1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1)C(F)(F)F InChI=1S/C27H29F3N2O3S/c1-26(33,27(28,29)30)22-13-11-20(12-14-22)18-32-16-15-31(19-25(32)21-7-4-3-5-8-21)23-9-6-10-24(17-23)36(2,34)35/h3-14,17,25,33H,15-16,18-19H2,1-2H3/t25-,26?/m1/s1 XCQRRLCJFNEFKV-DCWQJPKNSA-N 304565 (S)-1,1,1-trifluoro-2-(4-(((R)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 46-29::US10144715, Compound 46-30 Oxysterols receptor LXR-beta 1858 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304565&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554562 381753272 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584032 CC(O)(c1ccc(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1)C(F)(F)F InChI=1S/C27H29F3N2O3S/c1-26(33,27(28,29)30)22-13-11-20(12-14-22)18-32-16-15-31(19-25(32)21-7-4-3-5-8-21)23-9-6-10-24(17-23)36(2,34)35/h3-14,17,25,33H,15-16,18-19H2,1-2H3/t25-,26?/m1/s1 XCQRRLCJFNEFKV-DCWQJPKNSA-N 304565 (S)-1,1,1-trifluoro-2-(4-(((R)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 46-29::US10144715, Compound 46-30 Oxysterols receptor LXR-beta 216 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304565&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554562 381753272 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584034 CC(O)(c1ccc(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cc1)C(F)(F)F InChI=1S/C27H29F3N2O3S/c1-26(33,27(28,29)30)22-13-11-20(12-14-22)18-32-16-15-31(19-25(32)21-7-4-3-5-8-21)23-9-6-10-24(17-23)36(2,34)35/h3-14,17,25,33H,15-16,18-19H2,1-2H3/t25-,26?/m0/s1 XCQRRLCJFNEFKV-PMCHYTPCSA-N 304564 (S)-1,1,1-trifluoro-2-(4-(((S)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)phenyl)propan-2-ol::US10144715, Compound 46-28::US10144715, Compound 46-31 Oxysterols receptor LXR-beta 2166 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304564&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554561 381753271 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584036 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@@H](Cc2ccccc2)C1 InChI=1S/C26H26ClF3N2O2S/c1-35(33,34)23-9-5-8-21(16-23)32-13-12-31(22(18-32)14-19-6-3-2-4-7-19)17-20-10-11-24(25(27)15-20)26(28,29)30/h2-11,15-16,22H,12-14,17-18H2,1H3/t22-/m0/s1 HBGAEWRRFPYOSC-QFIPXVFZSA-N 304536 (S)-2-benzyl-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)piperazine::BDBM304568::US10144715, Compound 45-1 Oxysterols receptor LXR-beta 649 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304536&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872040 381753245 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584037 C[C@@]1(CN(CCN1Cc1ccc(c(Cl)c1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)c1ccccc1 InChI=1S/C26H26ClF3N2O2S/c1-25(20-7-4-3-5-8-20)18-31(21-9-6-10-22(16-21)35(2,33)34)13-14-32(25)17-19-11-12-23(24(27)15-19)26(28,29)30/h3-12,15-16H,13-14,17-18H2,1-2H3/t25-/m1/s1 MIEDXSUFXZLQDP-RUZDIDTESA-N 304569 (S)-1-(3-chloro-4-(trifluoromethyl)benzyl)-2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-34 Oxysterols receptor LXR-beta 32.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304569&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554563 381753274 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584039 C[C@@]1(CN(CCN1Cc1ccc(c(Cl)c1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)c1ccccc1 InChI=1S/C26H26ClF3N2O2S/c1-25(20-7-4-3-5-8-20)18-31(21-9-6-10-22(16-21)35(2,33)34)13-14-32(25)17-19-11-12-23(24(27)15-19)26(28,29)30/h3-12,15-16H,13-14,17-18H2,1-2H3/t25-/m1/s1 MIEDXSUFXZLQDP-RUZDIDTESA-N 304569 (S)-1-(3-chloro-4-(trifluoromethyl)benzyl)-2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-34 Oxysterols receptor LXR-beta 257 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304569&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554563 381753274 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584041 C[C@]1(CN(CCN1Cc1ccc(c(Cl)c1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)c1ccccc1 InChI=1S/C26H26ClF3N2O2S/c1-25(20-7-4-3-5-8-20)18-31(21-9-6-10-22(16-21)35(2,33)34)13-14-32(25)17-19-11-12-23(24(27)15-19)26(28,29)30/h3-12,15-16H,13-14,17-18H2,1-2H3/t25-/m0/s1 MIEDXSUFXZLQDP-VWLOTQADSA-N 304570 (R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-35 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304570&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554564 381753275 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584042 COC(=O)c1cc(CN2CCN(CC2c2ccccc2)c2cccc(c2)S(C)(=O)=O)ccc1C(F)(F)F InChI=1S/C27H27F3N2O4S/c1-36-26(33)23-15-19(11-12-24(23)27(28,29)30)17-32-14-13-31(18-25(32)20-7-4-3-5-8-20)21-9-6-10-22(16-21)37(2,34)35/h3-12,15-16,25H,13-14,17-18H2,1-2H3 VRESPJXJXRHWCT-UHFFFAOYSA-N 304571 US10144715, Compound 46-36::methyl 5-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)-2-(trifluoromethyl)benzoate Oxysterols receptor LXR-beta 244 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304571&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554565 381753276 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584043 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Br)c2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H24BrF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3 PGYSTOOIKGQJCU-UHFFFAOYSA-N 304572 1-(3-bromo-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-37 Oxysterols receptor LXR-beta 30.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304572&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554566 381753277 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584045 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2cccnc2)C(C1)c1ccccc1 InChI=1S/C23H25N3O2S/c1-29(27,28)22-11-5-10-21(15-22)25-13-14-26(17-19-7-6-12-24-16-19)23(18-25)20-8-3-2-4-9-20/h2-12,15-16,23H,13-14,17-18H2,1H3 PXOQYBBIEKPXOT-UHFFFAOYSA-N 304573 4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(pyridin-3-ylmethyl)piperazine::US10144715, Compound 46-39 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304573&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554567 381753278 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584047 Cc1ccc(CN2CCN(CC2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cn1 InChI=1S/C24H27N3O2S/c1-19-11-12-20(16-25-19)17-27-14-13-26(18-24(27)21-7-4-3-5-8-21)22-9-6-10-23(15-22)30(2,28)29/h3-12,15-16,24H,13-14,17-18H2,1-2H3 PXPNMQCYBIINHD-UHFFFAOYSA-N 304574 1-((6-methylpyridin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-40 Oxysterols receptor LXR-beta 17703 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304574&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554568 381753279 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584049 CC(C)[C@H]1CN(CCN1Cc1ccc(nc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H26F3N3O2S/c1-15(2)19-14-26(17-5-4-6-18(11-17)30(3,28)29)9-10-27(19)13-16-7-8-20(25-12-16)21(22,23)24/h4-8,11-12,15,19H,9-10,13-14H2,1-3H3/t19-/m1/s1 FVOQURUTFWMGIS-LJQANCHMSA-N 304575 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-41 Oxysterols receptor LXR-beta 161 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304575&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554569 381753280 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584051 CC(C)c1ccc(CN2CCN(CC2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cn1 InChI=1S/C26H31N3O2S/c1-20(2)25-13-12-21(17-27-25)18-29-15-14-28(19-26(29)22-8-5-4-6-9-22)23-10-7-11-24(16-23)32(3,30)31/h4-13,16-17,20,26H,14-15,18-19H2,1-3H3 CJVVVQGRSXIWNZ-UHFFFAOYSA-N 304576 1-((6-isopropylpyridin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-42 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304576&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554570 381753281 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584053 CC(C)c1ccc(CN2CCN(CC2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cn1 InChI=1S/C26H31N3O2S/c1-20(2)25-13-12-21(17-27-25)18-29-15-14-28(19-26(29)22-8-5-4-6-9-22)23-10-7-11-24(16-23)32(3,30)31/h4-13,16-17,20,26H,14-15,18-19H2,1-3H3 CJVVVQGRSXIWNZ-UHFFFAOYSA-N 304576 1-((6-isopropylpyridin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-42 Oxysterols receptor LXR-beta 1048 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304576&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554570 381753281 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584055 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3/t22-/m1/s1 CTCGRQVHZGKQJF-JOCHJYFZSA-N 304577 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-43 Oxysterols receptor LXR-beta 837 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304577&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554571 381753282 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584057 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3/t22-/m1/s1 CTCGRQVHZGKQJF-JOCHJYFZSA-N 304577 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-43 Oxysterols receptor LXR-beta 267 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304577&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554571 381753282 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584059 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3/t22-/m0/s1 CTCGRQVHZGKQJF-QFIPXVFZSA-N 304578 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-44 Oxysterols receptor LXR-beta 3963 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304578&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554572 381753283 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584061 Cc1ccccc1[C@@H]1CN(CCN1Cc1ccc(nc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H26F3N3O2S/c1-18-6-3-4-9-22(18)23-17-30(20-7-5-8-21(14-20)34(2,32)33)12-13-31(23)16-19-10-11-24(29-15-19)25(26,27)28/h3-11,14-15,23H,12-13,16-17H2,1-2H3/t23-/m0/s1 BDBOTQKIPWECIM-QHCPKHFHSA-N 304579 (R)-4-(3-(methylsulfonyl)phenyl)-2-(o-tolyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-45 Oxysterols receptor LXR-beta 1524 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304579&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554573 381753284 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584063 Cc1ccccc1[C@H]1CN(CCN1Cc1ccc(nc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H26F3N3O2S/c1-18-6-3-4-9-22(18)23-17-30(20-7-5-8-21(14-20)34(2,32)33)12-13-31(23)16-19-10-11-24(29-15-19)25(26,27)28/h3-11,14-15,23H,12-13,16-17H2,1-2H3/t23-/m1/s1 BDBOTQKIPWECIM-HSZRJFAPSA-N 304580 (S)-4-(3-(methylsulfonyl)phenyl)-2-(o-tolyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-46 Oxysterols receptor LXR-beta 1983 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304580&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554574 381753285 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584065 Cc1ccccc1[C@H]1CN(CCN1Cc1ccc(nc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H26F3N3O2S/c1-18-6-3-4-9-22(18)23-17-30(20-7-5-8-21(14-20)34(2,32)33)12-13-31(23)16-19-10-11-24(29-15-19)25(26,27)28/h3-11,14-15,23H,12-13,16-17H2,1-2H3/t23-/m1/s1 BDBOTQKIPWECIM-HSZRJFAPSA-N 304580 (S)-4-(3-(methylsulfonyl)phenyl)-2-(o-tolyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-46 Oxysterols receptor LXR-beta 1214 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304580&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554574 381753285 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584067 Cc1nc(ccc1CN1CCN(CC1c1ccccc1)c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C25H26F3N3O2S/c1-18-20(11-12-24(29-18)25(26,27)28)16-31-14-13-30(17-23(31)19-7-4-3-5-8-19)21-9-6-10-22(15-21)34(2,32)33/h3-12,15,23H,13-14,16-17H2,1-2H3 JMADGMMPWWZEJG-UHFFFAOYSA-N 304581 1-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-47 Oxysterols receptor LXR-beta 817 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304581&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554575 381753286 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584069 Cc1cc(CN2CCN(CC2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cnc1C(F)(F)F InChI=1S/C25H26F3N3O2S/c1-18-13-19(15-29-24(18)25(26,27)28)16-31-12-11-30(17-23(31)20-7-4-3-5-8-20)21-9-6-10-22(14-21)34(2,32)33/h3-10,13-15,23H,11-12,16-17H2,1-2H3 DZRXBHCLWHDURN-UHFFFAOYSA-N 304582 1-((5-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-48 Oxysterols receptor LXR-beta 443 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304582&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554576 381753287 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584071 Cc1cc(CN2CCN(CC2(C)c2ccccc2)c2cccc(c2)S(C)(=O)=O)cnc1C(F)(F)F InChI=1S/C26H28F3N3O2S/c1-19-14-20(16-30-24(19)26(27,28)29)17-32-13-12-31(18-25(32,2)21-8-5-4-6-9-21)22-10-7-11-23(15-22)35(3,33)34/h4-11,14-16H,12-13,17-18H2,1-3H3 LCNMJALEDMRJRG-UHFFFAOYSA-N 304583 2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-49 Oxysterols receptor LXR-beta 218 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304583&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554577 381753288 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584073 CS(=O)(=O)c1ccc(F)c(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H23F4N3O2S/c1-34(32,33)19-8-9-20(25)21(13-19)31-12-11-30(22(16-31)18-5-3-2-4-6-18)15-17-7-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3 WKCWHGGHDMRGIU-UHFFFAOYSA-N 304584 4-(2-fluoro-5-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-50 Oxysterols receptor LXR-beta 1907 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304584&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554578 381753289 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584075 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccc(F)cc1 InChI=1S/C24H23F4N3O2S/c1-34(32,33)21-4-2-3-20(13-21)30-11-12-31(22(16-30)18-6-8-19(25)9-7-18)15-17-5-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3 GHCIHXDQIODNPF-UHFFFAOYSA-N 304585 2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-51 Oxysterols receptor LXR-beta 450 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304585&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554579 381753290 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584077 CS(=O)(=O)c1cc(ccc1F)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H23F4N3O2S/c1-34(32,33)22-13-19(8-9-20(22)25)30-11-12-31(21(16-30)18-5-3-2-4-6-18)15-17-7-10-23(29-14-17)24(26,27)28/h2-10,13-14,21H,11-12,15-16H2,1H3 FOVQXOKFCNTHNJ-UHFFFAOYSA-N 304586 4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-52 Oxysterols receptor LXR-beta 1228 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304586&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554580 381753291 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584079 CS(=O)(=O)c1cc(F)cc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H23F4N3O2S/c1-34(32,33)21-12-19(25)11-20(13-21)30-9-10-31(22(16-30)18-5-3-2-4-6-18)15-17-7-8-23(29-14-17)24(26,27)28/h2-8,11-14,22H,9-10,15-16H2,1H3 LZXIZAUZKMNCPW-UHFFFAOYSA-N 304587 4-(3-fluoro-5-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-53 Oxysterols receptor LXR-beta 1520 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304587&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554581 381753292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584081 CS(=O)(=O)c1cc(F)cc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H23F4N3O2S/c1-34(32,33)21-12-19(25)11-20(13-21)30-9-10-31(22(16-30)18-5-3-2-4-6-18)15-17-7-8-23(29-14-17)24(26,27)28/h2-8,11-14,22H,9-10,15-16H2,1H3 LZXIZAUZKMNCPW-UHFFFAOYSA-N 304587 4-(3-fluoro-5-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-53 Oxysterols receptor LXR-beta 924 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304587&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554581 381753292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584083 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccc(Cl)cc1 InChI=1S/C24H23ClF3N3O2S/c1-34(32,33)21-4-2-3-20(13-21)30-11-12-31(22(16-30)18-6-8-19(25)9-7-18)15-17-5-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3 UKSLFOSELGAJFH-UHFFFAOYSA-N 304588 2-(4-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-54 Oxysterols receptor LXR-beta 1236 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304588&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554582 381753293 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584085 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1cccc(Cl)c1 InChI=1S/C24H23ClF3N3O2S/c1-34(32,33)21-7-3-6-20(13-21)30-10-11-31(22(16-30)18-4-2-5-19(25)12-18)15-17-8-9-23(29-14-17)24(26,27)28/h2-9,12-14,22H,10-11,15-16H2,1H3 ANUJRQJBYNNLFL-UHFFFAOYSA-N 304589 2-(3-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-55 Oxysterols receptor LXR-beta 794 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304589&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554583 381753294 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584087 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)[C@@H](C1)c1ccccc1Cl InChI=1S/C24H23ClF3N3O2S/c1-34(32,33)19-6-4-5-18(13-19)30-11-12-31(22(16-30)20-7-2-3-8-21(20)25)15-17-9-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3/t22-/m0/s1 YYVCZYRPPBVGDX-QFIPXVFZSA-N 304590 (R)-2-(2-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-56 Oxysterols receptor LXR-beta 2252 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304590&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554584 381753295 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584089 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)[C@H](C1)c1ccccc1Cl InChI=1S/C24H23ClF3N3O2S/c1-34(32,33)19-6-4-5-18(13-19)30-11-12-31(22(16-30)20-7-2-3-8-21(20)25)15-17-9-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3/t22-/m1/s1 YYVCZYRPPBVGDX-JOCHJYFZSA-N 304591 (S)-2-(2-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-57 Oxysterols receptor LXR-beta 61.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304591&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554585 381753296 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584091 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)[C@H](C1)c1ccccc1Cl InChI=1S/C24H23ClF3N3O2S/c1-34(32,33)19-6-4-5-18(13-19)30-11-12-31(22(16-30)20-7-2-3-8-21(20)25)15-17-9-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3/t22-/m1/s1 YYVCZYRPPBVGDX-JOCHJYFZSA-N 304591 (S)-2-(2-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-57 Oxysterols receptor LXR-beta 55.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304591&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554585 381753296 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584093 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H25F3N4O3S/c1-36(34,35)22-13-19(8-9-20(22)24(29)33)31-11-12-32(21(16-31)18-5-3-2-4-6-18)15-17-7-10-23(30-14-17)25(26,27)28/h2-10,13-14,21H,11-12,15-16H2,1H3,(H2,29,33) JNLXCTADTLBAKC-UHFFFAOYSA-N 304592 2-(methylsulfonyl)-4-(3-phenyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)benzamide::US10144715, Compound 46-58 Oxysterols receptor LXR-beta 2769 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304592&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554586 381753297 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584095 COC(=O)c1ccc(cc1S(C)(=O)=O)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C26H26F3N3O4S/c1-36-25(33)21-10-9-20(14-23(21)37(2,34)35)31-12-13-32(22(17-31)19-6-4-3-5-7-19)16-18-8-11-24(30-15-18)26(27,28)29/h3-11,14-15,22H,12-13,16-17H2,1-2H3 OZCHBKWUMMUQCS-UHFFFAOYSA-N 304593 US10144715, Compound 46-59::methyl 2-(methylsulfonyl)-4-(3-phenyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)benzoate Oxysterols receptor LXR-beta 3105 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304593&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872071 381753298 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584097 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1Br InChI=1S/C24H23BrF3N3O2S/c1-34(32,33)19-6-4-5-18(13-19)30-11-12-31(22(16-30)20-7-2-3-8-21(20)25)15-17-9-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3 OHHLQZZMNFJHFB-UHFFFAOYSA-N 304594 2-(2-bromophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-60 Oxysterols receptor LXR-beta 949 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304594&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554587 381753299 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584098 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccc(Br)cc1 InChI=1S/C24H23BrF3N3O2S/c1-34(32,33)21-4-2-3-20(13-21)30-11-12-31(22(16-30)18-6-8-19(25)9-7-18)15-17-5-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3 GZMQLISAMOYCAG-UHFFFAOYSA-N 304595 2-(4-bromophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-61 Oxysterols receptor LXR-beta 1350 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304595&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554588 381753300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584100 Cc1cccc(c1)C1CN(CCN1Cc1ccc(nc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H26F3N3O2S/c1-18-5-3-6-20(13-18)23-17-30(21-7-4-8-22(14-21)34(2,32)33)11-12-31(23)16-19-9-10-24(29-15-19)25(26,27)28/h3-10,13-15,23H,11-12,16-17H2,1-2H3 HCVLWMWRAMRONF-UHFFFAOYSA-N 304596 4-(3-(methylsulfonyl)phenyl)-2-(m-tolyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-62 Oxysterols receptor LXR-beta 657 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304596&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554589 381753301 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584102 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cn2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)18-6-3-2-4-7-18)16-20-11-10-19(15-28-20)24(25,26)27/h2-11,14-15,23H,12-13,16-17H2,1H3/t23-/m0/s1 XOZSNUDZALCIJG-QHCPKHFHSA-N 304597 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((5-(trifluoromethyl)pyridin-2-yl)methyl)piperazine::US10144715, Compound 46-63 Oxysterols receptor LXR-beta 7099 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304597&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883574 381753302 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584104 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cn2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)18-6-3-2-4-7-18)16-20-11-10-19(15-28-20)24(25,26)27/h2-11,14-15,23H,12-13,16-17H2,1H3/t23-/m1/s1 XOZSNUDZALCIJG-HSZRJFAPSA-N 304598 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((5-(trifluoromethyl)pyridin-2-yl)methyl)piperazine::US10144715, Compound 46-64 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304598&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883575 381753303 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584106 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cn2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)18-6-3-2-4-7-18)16-20-11-10-19(15-28-20)24(25,26)27/h2-11,14-15,23H,12-13,16-17H2,1H3/t23-/m1/s1 XOZSNUDZALCIJG-HSZRJFAPSA-N 304598 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((5-(trifluoromethyl)pyridin-2-yl)methyl)piperazine::US10144715, Compound 46-64 Oxysterols receptor LXR-beta 1864 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304598&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883575 381753303 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584108 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(o2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C23H23F3N2O3S/c1-32(29,30)20-9-5-8-18(14-20)27-12-13-28(21(16-27)17-6-3-2-4-7-17)15-19-10-11-22(31-19)23(24,25)26/h2-11,14,21H,12-13,15-16H2,1H3/t21-/m0/s1 CIVAXEXCZYXGTC-NRFANRHFSA-N 304599 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((5-(trifluoromethyl)furan-2-yl)methyl)piperazine::US10144715, Compound 46-65 Oxysterols receptor LXR-beta 5770 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304599&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883516 381753304 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584110 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(o2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C23H23F3N2O3S/c1-32(29,30)20-9-5-8-18(14-20)27-12-13-28(21(16-27)17-6-3-2-4-7-17)15-19-10-11-22(31-19)23(24,25)26/h2-11,14,21H,12-13,15-16H2,1H3/t21-/m1/s1 CIVAXEXCZYXGTC-OAQYLSRUSA-N 304600 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((5-(trifluoromethyl)furan-2-yl)methyl)piperazine::US10144715, Compound 46-66 Oxysterols receptor LXR-beta 207 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304600&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883523 381753305 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584112 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(o2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C23H23F3N2O3S/c1-32(29,30)20-9-5-8-18(14-20)27-12-13-28(21(16-27)17-6-3-2-4-7-17)15-19-10-11-22(31-19)23(24,25)26/h2-11,14,21H,12-13,15-16H2,1H3/t21-/m1/s1 CIVAXEXCZYXGTC-OAQYLSRUSA-N 304600 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((5-(trifluoromethyl)furan-2-yl)methyl)piperazine::US10144715, Compound 46-66 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304600&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883523 381753305 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584114 CS(=O)(=O)c1cc(ccc1CO)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H26F3N3O3S/c1-35(33,34)23-13-21(9-8-20(23)17-32)30-11-12-31(22(16-30)19-5-3-2-4-6-19)15-18-7-10-24(29-14-18)25(26,27)28/h2-10,13-14,22,32H,11-12,15-17H2,1H3 IPVMIWRZULJDJV-UHFFFAOYSA-N 304601 (2-(methylsulfonyl)-4-(3-phenyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)phenyl)methanol::US10144715, Compound 47-1 Oxysterols receptor LXR-beta 259 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304601&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872067 381753306 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584116 CC(C)[C@H]1CN(CCN1Cc1ccc(cc1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C23H29F3N2O3S/c1-16(2)21-14-27(20-9-6-18(15-29)22(12-20)32(3,30)31)10-11-28(21)13-17-4-7-19(8-5-17)23(24,25)26/h4-9,12,16,21,29H,10-11,13-15H2,1-3H3/t21-/m1/s1 BQYGVAKXZKJNFV-OAQYLSRUSA-N 304602 (S)-(4-(3-isopropyl-4-(4-(trifluoromethyl)benzyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 47-2 Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304602&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554590 381753307 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584118 CC(C)[C@H]1CN(CCN1Cc1ccc(c(Cl)c1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C23H28ClF3N2O3S/c1-15(2)21-13-28(18-6-5-17(14-30)22(11-18)33(3,31)32)8-9-29(21)12-16-4-7-19(20(24)10-16)23(25,26)27/h4-7,10-11,15,21,30H,8-9,12-14H2,1-3H3/t21-/m1/s1 VRELNUHLNWCSGQ-OAQYLSRUSA-N 304603 (S)-(4-(4-(3-fluoro-4-(trifluoromethyl)benzyl)-3-isopropylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 47-3 Oxysterols receptor LXR-beta 39.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304603&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554591 381753308 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584120 CS(=O)(=O)c1cc(ccc1CO)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C26H26ClF3N2O3S/c1-36(34,35)25-14-21(9-8-20(25)17-33)31-11-12-32(24(16-31)19-5-3-2-4-6-19)15-18-7-10-22(23(27)13-18)26(28,29)30/h2-10,13-14,24,33H,11-12,15-17H2,1H3 IBKVISPDVDTTMK-UHFFFAOYSA-N 304604 (4-(4-(3-chloro-4-(trifluoromethyl)benzyl)-3-phenylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 47-4 Oxysterols receptor LXR-beta 22.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304604&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554592 381753309 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584122 CC(C)[C@H]1CN(CCN1Cc1ccc(o1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N2O4S/c1-14(2)18-12-25(16-5-4-15(13-27)19(10-16)31(3,28)29)8-9-26(18)11-17-6-7-20(30-17)21(22,23)24/h4-7,10,14,18,27H,8-9,11-13H2,1-3H3/t18-/m1/s1 GHNYROVIKPIBMM-GOSISDBHSA-N 304605 (S)-(4-(3-isopropyl-4-((5-(trifluoromethyl)furan-2-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 47-5 Oxysterols receptor LXR-beta 109 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304605&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554593 381753310 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584125 CC(C)[C@H]1CN(CCN1C(=O)C1CCC(C)(C)CC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H36N2O3S/c1-17(2)21-16-24(19-7-6-8-20(15-19)29(5,27)28)13-14-25(21)22(26)18-9-11-23(3,4)12-10-18/h6-8,15,17-18,21H,9-14,16H2,1-5H3/t21-/m1/s1 QQRBREMSESSVRO-OAQYLSRUSA-N 304607 (S)-1-((4,4-dimethylcyclohexyl)methyl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 48-2 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304607&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554594 381753312 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584127 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CCC(O)(CC1)C(F)(F)F InChI=1S/C25H29F3N2O4S/c1-35(33,34)21-9-5-8-20(16-21)29-14-15-30(22(17-29)18-6-3-2-4-7-18)23(31)19-10-12-24(32,13-11-19)25(26,27)28/h2-9,16,19,22,32H,10-15,17H2,1H3/t19?,22-,24?/m0/s1 QLBMQRDKQRWAJI-GJFCNDCISA-N 304608 (R)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-3 Oxysterols receptor LXR-beta 221 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304608&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554595 381753313 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584129 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CCC(O)(CC1)C(F)(F)F InChI=1S/C25H29F3N2O4S/c1-35(33,34)21-9-5-8-20(16-21)29-14-15-30(22(17-29)18-6-3-2-4-7-18)23(31)19-10-12-24(32,13-11-19)25(26,27)28/h2-9,16,19,22,32H,10-15,17H2,1H3/t19?,22-,24?/m0/s1 QLBMQRDKQRWAJI-GJFCNDCISA-N 304608 (R)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-3 Oxysterols receptor LXR-beta 1321 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304608&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554595 381753313 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584131 CC1(C)CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C26H34N2O3S/c1-26(2)14-12-21(13-15-26)25(29)28-17-16-27(19-24(28)20-8-5-4-6-9-20)22-10-7-11-23(18-22)32(3,30)31/h4-11,18,21,24H,12-17,19H2,1-3H3/t24-/m1/s1 OCSBWUNDZQJSRW-XMMPIXPASA-N 304609 (S)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-4 Oxysterols receptor LXR-beta 10.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304609&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554596 381753314 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584133 CC1(C)CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C26H34N2O3S/c1-26(2)14-12-21(13-15-26)25(29)28-17-16-27(19-24(28)20-8-5-4-6-9-20)22-10-7-11-23(18-22)32(3,30)31/h4-11,18,21,24H,12-17,19H2,1-3H3/t24-/m1/s1 OCSBWUNDZQJSRW-XMMPIXPASA-N 304609 (S)-1-((4,4-dimethylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-4 Oxysterols receptor LXR-beta 18.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304609&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554596 381753314 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584135 CC1(O)CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H32N2O4S/c1-25(29)13-11-20(12-14-25)24(28)27-16-15-26(18-23(27)19-7-4-3-5-8-19)21-9-6-10-22(17-21)32(2,30)31/h3-10,17,20,23,29H,11-16,18H2,1-2H3/t20?,23-,25?/m1/s1 PICJKSLPJSZRIV-JKJRPBHFSA-N 304610 (1R,4s)-1-methyl-4-(((S)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)cyclohexan-1-ol::US10144715, Compound 48-5 Oxysterols receptor LXR-beta 123 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304610&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554597 381753315 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584137 CC1(O)CCC(CC1)C(=O)N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H32N2O4S/c1-25(29)13-11-20(12-14-25)24(28)27-16-15-26(18-23(27)19-7-4-3-5-8-19)21-9-6-10-22(17-21)32(2,30)31/h3-10,17,20,23,29H,11-16,18H2,1-2H3/t20?,23-,25?/m0/s1 PICJKSLPJSZRIV-KOXWRSSLSA-N 304611 (1S,4s)-1-methyl-4-(((R)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)cyclohexan-1-ol::US10144715, Compound 48-6 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304611&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554598 381753316 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584139 C[C@@]1(O)CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H32N2O4S/c1-25(29)13-11-20(12-14-25)24(28)27-16-15-26(18-23(27)19-7-4-3-5-8-19)21-9-6-10-22(17-21)32(2,30)31/h3-10,17,20,23,29H,11-16,18H2,1-2H3/t20?,23-,25-/m1/s1 PICJKSLPJSZRIV-ALRSMIOZSA-N 304612 (1S,4r)-1-methyl-4-(((S)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)cyclohexan-1-ol::US10144715, Compound 48-7 Oxysterols receptor LXR-beta 465 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304612&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554597 381753317 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584141 C[C@@]1(O)CCC(CC1)C(=O)N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H32N2O4S/c1-25(29)13-11-20(12-14-25)24(28)27-16-15-26(18-23(27)19-7-4-3-5-8-19)21-9-6-10-22(17-21)32(2,30)31/h3-10,17,20,23,29H,11-16,18H2,1-2H3/t20?,23-,25-/m0/s1 PICJKSLPJSZRIV-WAXYSGSMSA-N 304613 (1R,4r)-1-methyl-4-(((R)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)cyclohexan-1-ol::US10144715, Compound 48-8 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304613&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554598 381753318 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584143 CC(C)[C@@H]1CN(CCN1C(=O)C1CC[C@@](C)(O)CC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H34N2O4S/c1-16(2)20-15-23(18-6-5-7-19(14-18)29(4,27)28)12-13-24(20)21(25)17-8-10-22(3,26)11-9-17/h5-7,14,16-17,20,26H,8-13,15H2,1-4H3/t17?,20-,22-/m0/s1 YYFFXRNVMLUSIQ-FYQYPFLCSA-N 304614 (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-9 Oxysterols receptor LXR-beta 128 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304614&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554599 381753319 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584145 C[C@@]1(O)CCC(CC1)C(=O)N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H32N2O4S/c1-25(29)13-11-20(12-14-25)24(28)27-16-15-26(18-23(27)19-7-4-3-5-8-19)21-9-6-10-22(17-21)32(2,30)31/h3-10,17,20,23,29H,11-16,18H2,1-2H3/t20?,23-,25-/m0/s1 PICJKSLPJSZRIV-WAXYSGSMSA-N 304615 (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((1r,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-10 Oxysterols receptor LXR-beta 243 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304615&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554598 381753320 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584146 CC(C)[C@H]1CN(CCN1C(=O)C1CC[C@@](C)(O)CC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H34N2O4S/c1-16(2)20-15-23(18-6-5-7-19(14-18)29(4,27)28)12-13-24(20)21(25)17-8-10-22(3,26)11-9-17/h5-7,14,16-17,20,26H,8-13,15H2,1-4H3/t17?,20-,22-/m1/s1 YYFFXRNVMLUSIQ-SXHSKPAUSA-N 304616 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-11 Oxysterols receptor LXR-beta 2.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304616&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554600 381753321 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584148 C[C@@]1(O)CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H32N2O4S/c1-25(29)13-11-20(12-14-25)24(28)27-16-15-26(18-23(27)19-7-4-3-5-8-19)21-9-6-10-22(17-21)32(2,30)31/h3-10,17,20,23,29H,11-16,18H2,1-2H3/t20?,23-,25-/m1/s1 PICJKSLPJSZRIV-ALRSMIOZSA-N 304617 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-12 Oxysterols receptor LXR-beta 25.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304617&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554597 381753322 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584150 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CCC(F)(F)CC1 InChI=1S/C24H28F2N2O3S/c1-32(30,31)21-9-5-8-20(16-21)27-14-15-28(22(17-27)18-6-3-2-4-7-18)23(29)19-10-12-24(25,26)13-11-19/h2-9,16,19,22H,10-15,17H2,1H3/t22-/m1/s1 LWFAXHWAXCYXSZ-JOCHJYFZSA-N 304618 (S)-1-((4,4-difluorocyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-13 Oxysterols receptor LXR-beta 126 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304618&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554601 381753323 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584152 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CCC(F)(F)CC1 InChI=1S/C24H28F2N2O3S/c1-32(30,31)21-9-5-8-20(16-21)27-14-15-28(22(17-27)18-6-3-2-4-7-18)23(29)19-10-12-24(25,26)13-11-19/h2-9,16,19,22H,10-15,17H2,1H3/t22-/m1/s1 LWFAXHWAXCYXSZ-JOCHJYFZSA-N 304618 (S)-1-((4,4-difluorocyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-13 Oxysterols receptor LXR-beta 119 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304618&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554601 381753323 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584154 CC(C)[C@H]1CCC(CC1)C(=O)N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C27H36N2O3S/c1-20(2)21-12-14-23(15-13-21)27(30)29-17-16-28(19-26(29)22-8-5-4-6-9-22)24-10-7-11-25(18-24)33(3,31)32/h4-11,18,20-21,23,26H,12-17,19H2,1-3H3/t21-,23?,26-/m0/s1 FLFFTCOSOCINHR-OLRMMBPMSA-N 304619 (R)-1-(((1r,4R)-4-isopropylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-14 Oxysterols receptor LXR-beta 12255 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304619&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554602 381753324 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584155 CC(C)[C@H]1CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C27H36N2O3S/c1-20(2)21-12-14-23(15-13-21)27(30)29-17-16-28(19-26(29)22-8-5-4-6-9-22)24-10-7-11-25(18-24)33(3,31)32/h4-11,18,20-21,23,26H,12-17,19H2,1-3H3/t21-,23?,26-/m1/s1 FLFFTCOSOCINHR-XIHZFDFCSA-N 304620 (S)-1-(((1r,4S)-4-isopropylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-15 Oxysterols receptor LXR-beta 44.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304620&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554603 381753325 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584157 CC(C)[C@H]1CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C27H36N2O3S/c1-20(2)21-12-14-23(15-13-21)27(30)29-17-16-28(19-26(29)22-8-5-4-6-9-22)24-10-7-11-25(18-24)33(3,31)32/h4-11,18,20-21,23,26H,12-17,19H2,1-3H3/t21-,23?,26-/m1/s1 FLFFTCOSOCINHR-XIHZFDFCSA-N 304620 (S)-1-(((1r,4S)-4-isopropylcyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-15 Oxysterols receptor LXR-beta 197 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304620&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554603 381753325 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584159 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C25H30F2N2O3S/c1-33(31,32)22-9-5-8-21(16-22)28-14-15-29(23(17-28)18-6-3-2-4-7-18)25(30)20-12-10-19(11-13-20)24(26)27/h2-9,16,19-20,23-24H,10-15,17H2,1H3/t19-,20?,23-/m0/s1 XQHTVSOMTJRZEI-OKVILHKKSA-N 304621 (R)-1-(((1s,4S)-4-(difluoromethyl)cyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-16 Oxysterols receptor LXR-beta 454 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304621&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554604 381753326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584161 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C25H30F2N2O3S/c1-33(31,32)22-9-5-8-21(16-22)28-14-15-29(23(17-28)18-6-3-2-4-7-18)25(30)20-12-10-19(11-13-20)24(26)27/h2-9,16,19-20,23-24H,10-15,17H2,1H3/t19-,20?,23-/m1/s1 XQHTVSOMTJRZEI-GGFVOEBESA-N 304622 (S)-1-(((1s,4R)-4-(difluoromethyl)cyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-17 Oxysterols receptor LXR-beta 5.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304622&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554605 381753327 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584164 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C25H30F2N2O3S/c1-33(31,32)22-9-5-8-21(16-22)28-14-15-29(23(17-28)18-6-3-2-4-7-18)25(30)20-12-10-19(11-13-20)24(26)27/h2-9,16,19-20,23-24H,10-15,17H2,1H3/t19-,20?,23-/m0/s1 XQHTVSOMTJRZEI-OKVILHKKSA-N 304623 (R)-1-(((1r,4R)-4-(difluoromethyl)cyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-18 Oxysterols receptor LXR-beta 6083 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304623&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554604 381753328 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584166 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C25H30F2N2O3S/c1-33(31,32)22-9-5-8-21(16-22)28-14-15-29(23(17-28)18-6-3-2-4-7-18)25(30)20-12-10-19(11-13-20)24(26)27/h2-9,16,19-20,23-24H,10-15,17H2,1H3/t19-,20?,23-/m1/s1 XQHTVSOMTJRZEI-GGFVOEBESA-N 304624 (S)-1-(((1r,4S)-4-(difluoromethyl)cyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-19 Oxysterols receptor LXR-beta 56.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304624&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554605 381753329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584168 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C25H30F2N2O3S/c1-33(31,32)22-9-5-8-21(16-22)28-14-15-29(23(17-28)18-6-3-2-4-7-18)25(30)20-12-10-19(11-13-20)24(26)27/h2-9,16,19-20,23-24H,10-15,17H2,1H3/t19-,20?,23-/m1/s1 XQHTVSOMTJRZEI-GGFVOEBESA-N 304624 (S)-1-(((1r,4S)-4-(difluoromethyl)cyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-19 Oxysterols receptor LXR-beta 25048 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304624&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554605 381753329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584170 NS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C24H29F2N3O3S/c25-23(26)18-9-11-19(12-10-18)24(30)29-14-13-28(16-22(29)17-5-2-1-3-6-17)20-7-4-8-21(15-20)33(27,31)32/h1-8,15,18-19,22-23H,9-14,16H2,(H2,27,31,32)/t18-,19?,22-/m0/s1 JFJHGGFPJWKBFT-NOAQKIQUSA-N 304625 3-((R)-4-(((1r,4R)-4-(difluoromethyl)cyclohexyl)methyl)-3-phenylpiperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-20 Oxysterols receptor LXR-beta 1551 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304625&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554606 381753330 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584172 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C24H29F2N3O3S/c25-23(26)18-9-11-19(12-10-18)24(30)29-14-13-28(16-22(29)17-5-2-1-3-6-17)20-7-4-8-21(15-20)33(27,31)32/h1-8,15,18-19,22-23H,9-14,16H2,(H2,27,31,32)/t18-,19?,22-/m1/s1 JFJHGGFPJWKBFT-LROQTYINSA-N 304626 3-((S)-4-(((1r,4S)-4-(difluoromethyl)cyclohexyl)methyl)-3-phenylpiperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-21 Oxysterols receptor LXR-beta 175 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304626&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554607 381753331 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584174 NS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C24H29F2N3O3S/c25-23(26)18-9-11-19(12-10-18)24(30)29-14-13-28(16-22(29)17-5-2-1-3-6-17)20-7-4-8-21(15-20)33(27,31)32/h1-8,15,18-19,22-23H,9-14,16H2,(H2,27,31,32)/t18-,19?,22-/m0/s1 JFJHGGFPJWKBFT-NOAQKIQUSA-N 304627 3-((R)-4-(((1s,4S)-4-(difluoromethyl)cyclohexyl)methyl)-3-phenylpiperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-22 Oxysterols receptor LXR-beta 918 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304627&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554606 381753332 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584176 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)F InChI=1S/C24H29F2N3O3S/c25-23(26)18-9-11-19(12-10-18)24(30)29-14-13-28(16-22(29)17-5-2-1-3-6-17)20-7-4-8-21(15-20)33(27,31)32/h1-8,15,18-19,22-23H,9-14,16H2,(H2,27,31,32)/t18-,19?,22-/m1/s1 JFJHGGFPJWKBFT-LROQTYINSA-N 304628 3-((S)-4-(((1s,4R)-4-(difluoromethyl)cyclohexyl)methyl)-3-phenylpiperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-23 Oxysterols receptor LXR-beta 11.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304628&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554607 381753333 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584178 CC(C)[C@@H]1CN(CCN1C(=O)C1CC[C@@H](CC1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H30F4N2O3S/c1-14(2)19-13-27(17-8-9-18(23)20(12-17)32(3,30)31)10-11-28(19)21(29)15-4-6-16(7-5-15)22(24,25)26/h8-9,12,14-16,19H,4-7,10-11,13H2,1-3H3/t15?,16-,19-/m0/s1 PRDITVHZXOYDTE-RRSHCKCTSA-N 304629 (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropyl-1-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-24 Oxysterols receptor LXR-beta 55.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304629&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554608 381753334 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584180 CC(C)(O)[C@H]1CCC(CC1)C(=O)N1CCN(CC1c1ccccc1)c1cccc(c1)S(F)(=O)=O InChI=1S/C26H33FN2O4S/c1-26(2,31)21-13-11-20(12-14-21)25(30)29-16-15-28(18-24(29)19-7-4-3-5-8-19)22-9-6-10-23(17-22)34(27,32)33/h3-10,17,20-21,24,31H,11-16,18H2,1-2H3/t20?,21-,24? KCXHHPRFQFRJQX-WSSISSQWSA-N 304630 2-((1S,3R)-3-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)cyclohexyl)propan-2-ol::US10144715, Compound 48-25 Oxysterols receptor LXR-beta 178 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304630&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554609 381753335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584182 CC1(C)CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C28H38N2O4S/c1-28(2)14-11-23(12-15-28)27(32)30-17-16-29(20-25(30)21-7-5-4-6-8-21)24-10-9-22(13-18-31)26(19-24)35(3,33)34/h4-10,19,23,25,31H,11-18,20H2,1-3H3/t25-/m1/s1 MMFGEAJCSXYUPB-RUZDIDTESA-N 304631 (S)-(4-(4-((4,4-dimethylcyclohexyl)methyl)-3-phenylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-26 Oxysterols receptor LXR-beta 8.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304631&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554610 381753336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584184 CC1(C)CCC(CC1)C(=O)N1CCN(C[C@H]1c1ccccc1)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C28H38N2O4S/c1-28(2)14-11-23(12-15-28)27(32)30-17-16-29(20-25(30)21-7-5-4-6-8-21)24-10-9-22(13-18-31)26(19-24)35(3,33)34/h4-10,19,23,25,31H,11-18,20H2,1-3H3/t25-/m0/s1 MMFGEAJCSXYUPB-VWLOTQADSA-N 304632 (R)-(4-(4-((4,4-dimethylcyclohexyl)methyl)-3-phenylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-27 Oxysterols receptor LXR-beta 595 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304632&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554611 381753337 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584185 CC(F)(F)[C@H]1CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C26H32F2N2O3S/c1-26(27,28)21-13-11-20(12-14-21)25(31)30-16-15-29(18-24(30)19-7-4-3-5-8-19)22-9-6-10-23(17-22)34(2,32)33/h3-10,17,20-21,24H,11-16,18H2,1-2H3/t20?,21-,24-/m1/s1 QKNJYADOSHDXRP-RKSSIALMSA-N 304633 (S)-1-(((1s,4R)-4-(1,1-difluoroethyl)cyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-28 Oxysterols receptor LXR-beta 1341 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304633&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554612 381753338 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584186 CC(F)(F)[C@H]1CCC(CC1)C(=O)N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C26H32F2N2O3S/c1-26(27,28)21-13-11-20(12-14-21)25(31)30-16-15-29(18-24(30)19-7-4-3-5-8-19)22-9-6-10-23(17-22)34(2,32)33/h3-10,17,20-21,24H,11-16,18H2,1-2H3/t20?,21-,24-/m0/s1 QKNJYADOSHDXRP-AVJWOPLCSA-N 304634 (R)-1-(((1s,4S)-4-(1,1-difluoroethyl)cyclohexyl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-29 Oxysterols receptor LXR-beta 378 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304634&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554613 381753339 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584188 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H29F3N2O3S/c1-34(32,33)22-9-5-8-21(16-22)29-14-15-30(23(17-29)18-6-3-2-4-7-18)24(31)19-10-12-20(13-11-19)25(26,27)28/h2-9,16,19-20,23H,10-15,17H2,1H3/t19?,20-,23-/m0/s1 UKPWIODZPKIVBB-MQBGSOHWSA-N 304635 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-30 Oxysterols receptor LXR-beta 632 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304635&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554614 381753340 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584191 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H29F3N2O3S/c1-34(32,33)22-9-5-8-21(16-22)29-14-15-30(23(17-29)18-6-3-2-4-7-18)24(31)19-10-12-20(13-11-19)25(26,27)28/h2-9,16,19-20,23H,10-15,17H2,1H3/t19?,20-,23-/m1/s1 UKPWIODZPKIVBB-CXAYOUKQSA-N 304636 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-31 Oxysterols receptor LXR-beta 5.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304636&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554615 381753341 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584193 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H29F3N2O3S/c1-34(32,33)22-9-5-8-21(16-22)29-14-15-30(23(17-29)18-6-3-2-4-7-18)24(31)19-10-12-20(13-11-19)25(26,27)28/h2-9,16,19-20,23H,10-15,17H2,1H3/t19?,20-,23-/m1/s1 UKPWIODZPKIVBB-CXAYOUKQSA-N 304636 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-31 Oxysterols receptor LXR-beta 22.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304636&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554615 381753341 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584195 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H29F3N2O3S/c1-34(32,33)22-9-5-8-21(16-22)29-14-15-30(23(17-29)18-6-3-2-4-7-18)24(31)19-10-12-20(13-11-19)25(26,27)28/h2-9,16,19-20,23H,10-15,17H2,1H3/t19?,20-,23-/m0/s1 UKPWIODZPKIVBB-MQBGSOHWSA-N 304637 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((1r,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-32 Oxysterols receptor LXR-beta 3798 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304637&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554614 381753342 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584196 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H29F3N2O3S/c1-34(32,33)22-9-5-8-21(16-22)29-14-15-30(23(17-29)18-6-3-2-4-7-18)24(31)19-10-12-20(13-11-19)25(26,27)28/h2-9,16,19-20,23H,10-15,17H2,1H3/t19?,20-,23-/m1/s1 UKPWIODZPKIVBB-CXAYOUKQSA-N 304638 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-33 Oxysterols receptor LXR-beta 41.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304638&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554615 381753343 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584198 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H29F3N2O3S/c1-34(32,33)22-9-5-8-21(16-22)29-14-15-30(23(17-29)18-6-3-2-4-7-18)24(31)19-10-12-20(13-11-19)25(26,27)28/h2-9,16,19-20,23H,10-15,17H2,1H3/t19?,20-,23-/m1/s1 UKPWIODZPKIVBB-CXAYOUKQSA-N 304638 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-33 Oxysterols receptor LXR-beta 375 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304638&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554615 381753343 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584200 NS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C24H28F3N3O3S/c25-24(26,27)19-11-9-18(10-12-19)23(31)30-14-13-29(16-22(30)17-5-2-1-3-6-17)20-7-4-8-21(15-20)34(28,32)33/h1-8,15,18-19,22H,9-14,16H2,(H2,28,32,33)/t18?,19-,22-/m0/s1 YBWLALOIFCWSFM-MLLWHUAMSA-N 304639 3-((R)-3-phenyl-4-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-34 Oxysterols receptor LXR-beta 704 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304639&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554616 381753344 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584202 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C24H28F3N3O3S/c25-24(26,27)19-11-9-18(10-12-19)23(31)30-14-13-29(16-22(30)17-5-2-1-3-6-17)20-7-4-8-21(15-20)34(28,32)33/h1-8,15,18-19,22H,9-14,16H2,(H2,28,32,33)/t18?,19-,22-/m1/s1 YBWLALOIFCWSFM-IPNFRKERSA-N 304640 3-((S)-3-phenyl-4-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-35 Oxysterols receptor LXR-beta 46.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304640&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554617 381753345 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584204 NS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C24H28F3N3O3S/c25-24(26,27)19-11-9-18(10-12-19)23(31)30-14-13-29(16-22(30)17-5-2-1-3-6-17)20-7-4-8-21(15-20)34(28,32)33/h1-8,15,18-19,22H,9-14,16H2,(H2,28,32,33)/t18?,19-,22-/m0/s1 YBWLALOIFCWSFM-MLLWHUAMSA-N 304641 3-((R)-3-phenyl-4-(((1r,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-36 Oxysterols receptor LXR-beta 16356 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304641&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554616 381753346 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584206 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C24H28F3N3O3S/c25-24(26,27)19-11-9-18(10-12-19)23(31)30-14-13-29(16-22(30)17-5-2-1-3-6-17)20-7-4-8-21(15-20)34(28,32)33/h1-8,15,18-19,22H,9-14,16H2,(H2,28,32,33)/t18?,19-,22-/m1/s1 YBWLALOIFCWSFM-IPNFRKERSA-N 304642 3-((S)-3-phenyl-4-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-37 Oxysterols receptor LXR-beta 1294 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304642&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554617 381753347 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584208 CC(C)[C@H]1CN(CCN1CC1CCC(O)(CC1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C23H35F3N2O4S/c1-16(2)20-14-27(19-5-4-18(15-29)21(12-19)33(3,31)32)10-11-28(20)13-17-6-8-22(30,9-7-17)23(24,25)26/h4-5,12,16-17,20,29-30H,6-11,13-15H2,1-3H3/t17?,20-,22?/m1/s1 QJYYCRLEFSTQSM-LVKMRUPZSA-N 304643 (S)-4-((4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)methyl)-1-(trifluoromethyl)cyclohexan-1-ol::US10144715, Compound 48-38 Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304643&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883479 381753348 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584210 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccc(F)cc1)C(=O)C1CCC[C@H](C1)C(F)(F)F InChI=1S/C24H27F4N3O3S/c25-19-9-7-16(8-10-19)22-15-30(20-5-2-6-21(14-20)35(29,33)34)11-12-31(22)23(32)17-3-1-4-18(13-17)24(26,27)28/h2,5-10,14,17-18,22H,1,3-4,11-13,15H2,(H2,29,33,34)/t17?,18-,22-/m1/s1 BKOKGTVPLDCTIS-WMISUKIASA-N 304644 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((1R,3R)-3-(trifluoromethyl)cyclohexyl)methyl)piperazine::BDBM304645::US10144715, Compound 48-39 Oxysterols receptor LXR-beta 7.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304644&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554618 381753349 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584212 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccc(F)cc1)C(=O)C1CCC[C@H](C1)C(F)(F)F InChI=1S/C24H27F4N3O3S/c25-19-9-7-16(8-10-19)22-15-30(20-5-2-6-21(14-20)35(29,33)34)11-12-31(22)23(32)17-3-1-4-18(13-17)24(26,27)28/h2,5-10,14,17-18,22H,1,3-4,11-13,15H2,(H2,29,33,34)/t17?,18-,22-/m1/s1 BKOKGTVPLDCTIS-WMISUKIASA-N 304644 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((1R,3R)-3-(trifluoromethyl)cyclohexyl)methyl)piperazine::BDBM304645::US10144715, Compound 48-39 Oxysterols receptor LXR-beta 156 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304644&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554618 381753349 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584214 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccc(F)cc1)C(=O)C1CCC[C@@H](C1)C(F)(F)F InChI=1S/C24H27F4N3O3S/c25-19-9-7-16(8-10-19)22-15-30(20-5-2-6-21(14-20)35(29,33)34)11-12-31(22)23(32)17-3-1-4-18(13-17)24(26,27)28/h2,5-10,14,17-18,22H,1,3-4,11-13,15H2,(H2,29,33,34)/t17?,18-,22+/m0/s1 BKOKGTVPLDCTIS-RXJZEZJSSA-N 304646 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((1R,3S)-3-(trifluoromethyl)cyclohexyl)methyl)piperazine::BDBM304647::US10144715, Compound 48-41 Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304646&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554619 381753351 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584215 NS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccc(F)cc1)C(=O)C1CCC[C@@H](C1)C(F)(F)F InChI=1S/C24H27F4N3O3S/c25-19-9-7-16(8-10-19)22-15-30(20-5-2-6-21(14-20)35(29,33)34)11-12-31(22)23(32)17-3-1-4-18(13-17)24(26,27)28/h2,5-10,14,17-18,22H,1,3-4,11-13,15H2,(H2,29,33,34)/t17?,18-,22+/m0/s1 BKOKGTVPLDCTIS-RXJZEZJSSA-N 304646 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((1R,3S)-3-(trifluoromethyl)cyclohexyl)methyl)piperazine::BDBM304647::US10144715, Compound 48-41 Oxysterols receptor LXR-beta 207 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304646&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554619 381753351 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584216 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C25H30F4N2O2S/c1-34(32,33)23-4-2-3-22(15-23)30-13-14-31(24(17-30)19-7-11-21(26)12-8-19)16-18-5-9-20(10-6-18)25(27,28)29/h2-4,7-8,11-12,15,18,20,24H,5-6,9-10,13-14,16-17H2,1H3/t18-,20+,24-/m1/s1 KJSOJQZBLHRWCR-LJFZDNNRSA-N 304648 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-43 Oxysterols receptor LXR-beta 15.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304648&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883476 381753353 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584218 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C25H30F4N2O2S/c1-34(32,33)23-4-2-3-22(15-23)30-13-14-31(24(17-30)19-7-11-21(26)12-8-19)16-18-5-9-20(10-6-18)25(27,28)29/h2-4,7-8,11-12,15,18,20,24H,5-6,9-10,13-14,16-17H2,1H3/t18-,20+,24-/m1/s1 KJSOJQZBLHRWCR-LJFZDNNRSA-N 304648 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-43 Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304648&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883476 381753353 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584220 CS(=O)(=O)c1cc(ccc1CCO)N1CCN([C@@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C27H33F3N2O4S/c1-37(35,36)25-17-23(12-9-20(25)13-16-33)31-14-15-32(24(18-31)19-5-3-2-4-6-19)26(34)21-7-10-22(11-8-21)27(28,29)30/h2-6,9,12,17,21-22,24,33H,7-8,10-11,13-16,18H2,1H3/t21?,22-,24-/m0/s1 XTNJZYDDNHOSBX-OVOHSDETSA-N 304649 (2-(methylsulfonyl)-4-((R)-3-phenyl-4-(((1r,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)phenyl)methanol::US10144715, Compound 48-44 Oxysterols receptor LXR-beta 972 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304649&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554620 381753354 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584222 CS(=O)(=O)c1cc(ccc1CCO)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C27H33F3N2O4S/c1-37(35,36)25-17-23(12-9-20(25)13-16-33)31-14-15-32(24(18-31)19-5-3-2-4-6-19)26(34)21-7-10-22(11-8-21)27(28,29)30/h2-6,9,12,17,21-22,24,33H,7-8,10-11,13-16,18H2,1H3/t21?,22-,24-/m1/s1 XTNJZYDDNHOSBX-YUWPFLFCSA-N 304650 (2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)phenyl)methanol::US10144715, Compound 48-45 Oxysterols receptor LXR-beta 21.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304650&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554621 381753355 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584223 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1Cl)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H28ClF3N2O3S/c1-35(33,34)20-6-4-5-19(15-20)30-13-14-31(23(16-30)21-7-2-3-8-22(21)26)24(32)17-9-11-18(12-10-17)25(27,28)29/h2-8,15,17-18,23H,9-14,16H2,1H3/t17?,18-,23-/m1/s1 FLLKLMGHHSZMMY-ZAZMHIJSSA-N 304651 (S)-2-(2-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-46 Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304651&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554622 381753356 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584225 CS(=O)(=O)c1cc(ccc1F)N1CCN([C@H](C1)c1ccc(F)cc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H27F5N2O3S/c1-36(34,35)23-14-20(10-11-21(23)27)31-12-13-32(22(15-31)16-4-8-19(26)9-5-16)24(33)17-2-6-18(7-3-17)25(28,29)30/h4-5,8-11,14,17-18,22H,2-3,6-7,12-13,15H2,1H3/t17?,18-,22-/m1/s1 HVOUQCTVPWXRRS-WMISUKIASA-N 304652 (S)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)-1-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-48 Oxysterols receptor LXR-beta 23.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304652&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554623 381753357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584227 CS(=O)(=O)c1cc(ccc1F)N1CCN([C@H](C1)c1ccc(F)cc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C25H27F5N2O3S/c1-36(34,35)23-14-20(10-11-21(23)27)31-12-13-32(22(15-31)16-4-8-19(26)9-5-16)24(33)17-2-6-18(7-3-17)25(28,29)30/h4-5,8-11,14,17-18,22H,2-3,6-7,12-13,15H2,1H3/t17?,18-,22-/m1/s1 HVOUQCTVPWXRRS-WMISUKIASA-N 304652 (S)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)-1-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-48 Oxysterols receptor LXR-beta 142 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304652&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554623 381753357 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584229 COCCc1ccc(cc1S(C)(=O)=O)N1CCN([C@H](C1)c1ccccc1)C(=O)C1CC[C@@H](CC1)C(F)(F)F InChI=1S/C28H35F3N2O4S/c1-37-17-14-21-10-13-24(18-26(21)38(2,35)36)32-15-16-33(25(19-32)20-6-4-3-5-7-20)27(34)22-8-11-23(12-9-22)28(29,30)31/h3-7,10,13,18,22-23,25H,8-9,11-12,14-17,19H2,1-2H3/t22?,23-,25-/m1/s1 GAQQGQVTXXRZCH-VCGBWKKMSA-N 304653 (S)-4-(4-(methoxymethyl)-3-(methylsulfonyl)phenyl)-2-phenyl-1-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazine::US10144715, Compound 48-49 Oxysterols receptor LXR-beta 1490 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304653&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554624 381753358 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584231 CC(C)[C@H]1CN(CCN1CC1CCN(CC(F)(F)F)CC1)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C24H38F3N3O3S/c1-18(2)22-16-29(21-5-4-20(8-13-31)23(14-21)34(3,32)33)11-12-30(22)15-19-6-9-28(10-7-19)17-24(25,26)27/h4-5,14,18-19,22,31H,6-13,15-17H2,1-3H3/t22-/m1/s1 ATFXXADQEVAPEW-JOCHJYFZSA-N 304654 (S)-(4-(3-isopropyl-4-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-50 Oxysterols receptor LXR-beta 89.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304654&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554625 381753359 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584233 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCN(CC(F)(F)F)CC2)[C@@H](C1)c1ccccc1 InChI=1S/C25H32F3N3O2S/c1-34(32,33)23-9-5-8-22(16-23)30-14-15-31(24(18-30)21-6-3-2-4-7-21)17-20-10-12-29(13-11-20)19-25(26,27)28/h2-9,16,20,24H,10-15,17-19H2,1H3/t24-/m0/s1 GORKTTGPOWEAKY-DEOSSOPVSA-N 304655 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazine::US10144715, Compound 48-51 Oxysterols receptor LXR-beta 4851 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304655&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554626 381753360 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584235 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCN(CC(F)(F)F)CC2)[C@H](C1)c1ccccc1 InChI=1S/C25H32F3N3O2S/c1-34(32,33)23-9-5-8-22(16-23)30-14-15-31(24(18-30)21-6-3-2-4-7-21)17-20-10-12-29(13-11-20)19-25(26,27)28/h2-9,16,20,24H,10-15,17-19H2,1H3/t24-/m1/s1 GORKTTGPOWEAKY-XMMPIXPASA-N 304656 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazine::US10144715, Compound 48-52 Oxysterols receptor LXR-beta 68.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304656&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554627 381753361 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584237 CS(=O)(=O)c1cccc(c1)N1CCN(CC2(F)CCN(CC(F)(F)F)CC2)[C@H](C1)c1ccccc1 InChI=1S/C25H31F4N3O2S/c1-35(33,34)22-9-5-8-21(16-22)31-14-15-32(23(17-31)20-6-3-2-4-7-20)18-24(26)10-12-30(13-11-24)19-25(27,28)29/h2-9,16,23H,10-15,17-19H2,1H3/t23-/m1/s1 XFSCVGWGYBAUOK-HSZRJFAPSA-N 304657 (S)-1-((4-fluoro-1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-53 Oxysterols receptor LXR-beta 259 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304657&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554628 381753362 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584239 CS(=O)(=O)c1cccc(c1)N1CCN(CC2(F)CCN(CC(F)(F)F)CC2)[C@@H](C1)c1ccccc1 InChI=1S/C25H31F4N3O2S/c1-35(33,34)22-9-5-8-21(16-22)31-14-15-32(23(17-31)20-6-3-2-4-7-20)18-24(26)10-12-30(13-11-24)19-25(27,28)29/h2-9,16,23H,10-15,17-19H2,1H3/t23-/m0/s1 XFSCVGWGYBAUOK-QHCPKHFHSA-N 304658 (R)-1-((4-fluoro-1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-54 Oxysterols receptor LXR-beta 2386 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304658&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554629 381753363 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584241 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCN(CC(F)(F)F)CC2)[C@H](C1)c1ccccc1Cl InChI=1S/C25H31ClF3N3O2S/c1-35(33,34)21-6-4-5-20(15-21)31-13-14-32(24(17-31)22-7-2-3-8-23(22)26)16-19-9-11-30(12-10-19)18-25(27,28)29/h2-8,15,19,24H,9-14,16-18H2,1H3/t24-/m1/s1 DJSVQYMUGOLIIN-XMMPIXPASA-N 304659 (S)-2-(2-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazine::US10144715, Compound 48-55 Oxysterols receptor LXR-beta 67.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304659&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554630 381753364 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584242 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCN(CC(F)(F)F)CC2)[C@@H](C1)c1ccccc1Cl InChI=1S/C25H31ClF3N3O2S/c1-35(33,34)21-6-4-5-20(15-21)31-13-14-32(24(17-31)22-7-2-3-8-23(22)26)16-19-9-11-30(12-10-19)18-25(27,28)29/h2-8,15,19,24H,9-14,16-18H2,1H3/t24-/m0/s1 DJSVQYMUGOLIIN-DEOSSOPVSA-N 304660 (R)-2-(2-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazine::US10144715, Compound 48-56 Oxysterols receptor LXR-beta 1672 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304660&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554631 381753365 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584243 CS(=O)(=O)c1cccc(c1)N1CCN(CC2(F)CCN(CC(F)(F)F)CC2)[C@H](C1)c1ccc(F)cc1 InChI=1S/C25H30F5N3O2S/c1-36(34,35)22-4-2-3-21(15-22)32-13-14-33(23(16-32)19-5-7-20(26)8-6-19)17-24(27)9-11-31(12-10-24)18-25(28,29)30/h2-8,15,23H,9-14,16-18H2,1H3/t23-/m1/s1 KUGPTBUWNYMYDW-HSZRJFAPSA-N 304661 (S)-1-((4-fluoro-1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 48-57 Oxysterols receptor LXR-beta 492 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304661&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554632 381753366 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584245 CC(C)[C@H]1CN(CCN1C[C@@H]1CCN(CC(F)(F)F)C1)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C23H36F3N3O3S/c1-17(2)21-15-28(20-5-4-19(7-11-30)22(12-20)33(3,31)32)9-10-29(21)14-18-6-8-27(13-18)16-23(24,25)26/h4-5,12,17-18,21,30H,6-11,13-16H2,1-3H3/t18-,21-/m1/s1 YQRNMJRNNZXKKP-WIYYLYMNSA-N 304662 (4-((S)-3-isopropyl-4-(((S)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-58 Oxysterols receptor LXR-beta 680 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304662&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554633 381753367 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584247 CC(C)[C@H]1CN(CCN1C[C@H]1CCN(CC(F)(F)F)C1)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C23H36F3N3O3S/c1-17(2)21-15-28(20-5-4-19(7-11-30)22(12-20)33(3,31)32)9-10-29(21)14-18-6-8-27(13-18)16-23(24,25)26/h4-5,12,17-18,21,30H,6-11,13-16H2,1-3H3/t18-,21+/m0/s1 YQRNMJRNNZXKKP-GHTZIAJQSA-N 304663 (4-((S)-3-isopropyl-4-(((R)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-59 Oxysterols receptor LXR-beta 415 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304663&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554634 381753368 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583465 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H30N2O4S/c1-14(2)17-13-20(10-11-21(17)18(22)25-19(3,4)5)15-8-7-9-16(12-15)26(6,23)24/h7-9,12,14,17H,10-11,13H2,1-6H3/t17-/m0/s1 HDOWNKAPIXMAAE-KRWDZBQOSA-N 304288 US10144715, Compound 1-1::US10144715, Compound 2-2::tert-butyl (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 157 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883536 381753003 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583467 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H30N2O4S/c1-14(2)17-13-20(10-11-21(17)18(22)25-19(3,4)5)15-8-7-9-16(12-15)26(6,23)24/h7-9,12,14,17H,10-11,13H2,1-6H3/t17-/m0/s1 HDOWNKAPIXMAAE-KRWDZBQOSA-N 304288 US10144715, Compound 1-1::US10144715, Compound 2-2::tert-butyl (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 15.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883536 381753003 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583469 CCC(C)[C@H]1CN(CCN1C(=O)OC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H32N2O4S/c1-7-15(2)18-14-21(11-12-22(18)19(23)26-20(3,4)5)16-9-8-10-17(13-16)27(6,24)25/h8-10,13,15,18H,7,11-12,14H2,1-6H3/t15?,18-/m1/s1 AKYJJHPDFWVLIM-KPMSDPLLSA-N 304289 US10144715, Compound 1-2::tert-butyl (S)-2-isobutyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 258 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304289&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554377 381753004 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583472 COC(=O)[C@H]1CN(CCN1C(=O)OC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C18H26N2O6S/c1-18(2,3)26-17(22)20-10-9-19(12-15(20)16(21)25-4)13-7-6-8-14(11-13)27(5,23)24/h6-8,11,15H,9-10,12H2,1-5H3/t15-/m1/s1 UPCYOFHXRBZBPA-OAHLLOKOSA-N 304291 1-(tert-butyl) 2-methyl (S)-4-(3-(methylsulfonyl)phenyl)piperazine-1,2-dicarboxylate::US10144715, Compound 1-4 Oxysterols receptor LXR-beta 2057 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304291&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554379 381753006 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583474 CC(C)(C)OC(=O)N1CCN(CC1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H28N2O4S/c1-22(2,3)28-21(25)24-14-13-23(16-20(24)17-9-6-5-7-10-17)18-11-8-12-19(15-18)29(4,26)27/h5-12,15,20H,13-14,16H2,1-4H3 QOZZSQFYXBVSQA-UHFFFAOYSA-N 304292 US10144715, Compound 1-5::tert-butyl 4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 227 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304292&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554380 381753007 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583476 CC(C)(C)OC(=O)N1CCN(C[C@@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H28N2O4S/c1-22(2,3)28-21(25)24-14-13-23(16-20(24)17-9-6-5-7-10-17)18-11-8-12-19(15-18)29(4,26)27/h5-12,15,20H,13-14,16H2,1-4H3/t20-/m1/s1 QOZZSQFYXBVSQA-HXUWFJFHSA-N 304293 US10144715, Compound 1-6::tert-butyl (S)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 12472 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304293&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554381 381753008 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583478 CC(C)(C)OC(=O)N1CCN(C[C@@H]1Cc1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H30N2O4S/c1-23(2,3)29-22(26)25-14-13-24(17-20(25)15-18-9-6-5-7-10-18)19-11-8-12-21(16-19)30(4,27)28/h5-12,16,20H,13-15,17H2,1-4H3/t20-/m0/s1 WXTIZJALIIAVIJ-FQEVSTJZSA-N 304294 US10144715, Compound 1-7::tert-butyl (S)-2-benzyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304294&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554382 381753009 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583480 CC(C)(C)OC(=O)N1CCN(C[C@H]1Cc1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H30N2O4S/c1-23(2,3)29-22(26)25-14-13-24(17-20(25)15-18-9-6-5-7-10-18)19-11-8-12-21(16-19)30(4,27)28/h5-12,16,20H,13-15,17H2,1-4H3/t20-/m1/s1 WXTIZJALIIAVIJ-HXUWFJFHSA-N 304295 US10144715, Compound 1-8::tert-butyl (R)-2-benzyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 55.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304295&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554383 381753010 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583482 CC(C)(C)OC(=O)N1CCN(CC1c1ccccc1Br)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H27BrN2O4S/c1-22(2,3)29-21(26)25-13-12-24(15-20(25)18-10-5-6-11-19(18)23)16-8-7-9-17(14-16)30(4,27)28/h5-11,14,20H,12-13,15H2,1-4H3 LKQXPNBHFZRAFV-UHFFFAOYSA-N 304296 US10144715, Compound 1-9::tert-butyl 2-(2-bromophenyl)-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 564 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304296&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554384 381753011 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583484 CC(C)(C)OC(=O)N1CCN(CC1(C)c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H30N2O4S/c1-22(2,3)29-21(26)25-15-14-24(17-23(25,4)18-10-7-6-8-11-18)19-12-9-13-20(16-19)30(5,27)28/h6-13,16H,14-15,17H2,1-5H3 ZRXYZNMALXWEOH-UHFFFAOYSA-N 304297 US10144715, Compound 1-10::tert-butyl 2-methyl-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 500 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304297&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554385 381753012 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584249 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2CCN(CC(F)(F)F)C2)[C@@H](C1)c1ccccc1 InChI=1S/C24H30F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)20-6-3-2-4-7-20)16-19-10-11-28(15-19)18-24(25,26)27/h2-9,14,19,23H,10-13,15-18H2,1H3/t19-,23+/m1/s1 ASEZPZHKRBKKJY-XXBNENTESA-N 304664 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((S)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazine::US10144715, Compound 48-60 Oxysterols receptor LXR-beta 1032 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304664&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554635 381753369 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584251 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2CCN(CC(F)(F)F)C2)[C@H](C1)c1ccccc1 InChI=1S/C24H30F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)20-6-3-2-4-7-20)16-19-10-11-28(15-19)18-24(25,26)27/h2-9,14,19,23H,10-13,15-18H2,1H3/t19-,23-/m1/s1 ASEZPZHKRBKKJY-AUSIDOKSSA-N 304665 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((R)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazine::US10144715, Compound 48-61 Oxysterols receptor LXR-beta 417 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304665&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554636 381753370 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584253 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2CCN(CC(F)(F)F)C2)[C@H](C1)c1ccccc1 InChI=1S/C24H30F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)20-6-3-2-4-7-20)16-19-10-11-28(15-19)18-24(25,26)27/h2-9,14,19,23H,10-13,15-18H2,1H3/t19-,23-/m1/s1 ASEZPZHKRBKKJY-AUSIDOKSSA-N 304665 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((R)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazine::US10144715, Compound 48-61 Oxysterols receptor LXR-beta 112 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304665&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554636 381753370 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584255 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CCN(CC(F)(F)F)C2)[C@@H](C1)c1ccccc1 InChI=1S/C24H30F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)20-6-3-2-4-7-20)16-19-10-11-28(15-19)18-24(25,26)27/h2-9,14,19,23H,10-13,15-18H2,1H3/t19-,23-/m0/s1 ASEZPZHKRBKKJY-CVDCTZTESA-N 304666 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((R)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazine::US10144715, Compound 48-62 Oxysterols receptor LXR-beta 2100 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304666&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554637 381753371 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584257 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CCN(CC(F)(F)F)C2)[C@H](C1)c1ccccc1 InChI=1S/C24H30F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)20-6-3-2-4-7-20)16-19-10-11-28(15-19)18-24(25,26)27/h2-9,14,19,23H,10-13,15-18H2,1H3/t19-,23+/m0/s1 ASEZPZHKRBKKJY-WMZHIEFXSA-N 304667 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((S)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazine::US10144715, Compound 48-63 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304667&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554638 381753372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584259 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CCN(CC(F)(F)F)C2)[C@H](C1)c1ccccc1 InChI=1S/C24H30F3N3O2S/c1-33(31,32)22-9-5-8-21(14-22)29-12-13-30(23(17-29)20-6-3-2-4-7-20)16-19-10-11-28(15-19)18-24(25,26)27/h2-9,14,19,23H,10-13,15-18H2,1H3/t19-,23+/m0/s1 ASEZPZHKRBKKJY-WMZHIEFXSA-N 304667 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(((S)-1-(2,2,2-trifluoroethyl)pyrrolidin-3-yl)methyl)piperazine::US10144715, Compound 48-63 Oxysterols receptor LXR-beta 1553 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304667&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554638 381753372 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584261 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2C[C@H]3[C@@H](C2)C3(F)F)[C@H](C1)c1ccccc1 InChI=1S/C24H28F2N2O2S/c1-31(29,30)20-9-5-8-19(14-20)27-10-11-28(23(16-27)18-6-3-2-4-7-18)15-17-12-21-22(13-17)24(21,25)26/h2-9,14,17,21-23H,10-13,15-16H2,1H3/t17-,21+,22-,23-/m1/s1 UZNDKNPMFSVFET-FJTGNWTPSA-N 304668 (S)-1-(((1R,3r,5S)-6,6-difluorobicyclo[3.1.0]hexan-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-64 Oxysterols receptor LXR-beta 38.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304668&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883576 381753373 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584263 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2C[C@H]3[C@@H](C2)C3(F)F)[C@H](C1)c1ccccc1 InChI=1S/C24H28F2N2O2S/c1-31(29,30)20-9-5-8-19(14-20)27-10-11-28(23(16-27)18-6-3-2-4-7-18)15-17-12-21-22(13-17)24(21,25)26/h2-9,14,17,21-23H,10-13,15-16H2,1H3/t17-,21-,22+,23-/m1/s1 UZNDKNPMFSVFET-OCYFJXFZSA-N 304669 (S)-1-(((1R,3s,5S)-6,6-difluorobicyclo[3.1.0]hexan-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-66 Oxysterols receptor LXR-beta 103 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304669&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883576 381753374 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584264 CC(C)[C@H]1CN(CCN1CC1CCC(CC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H33F3N2O2S/c1-16(2)21-15-26(19-5-4-6-20(13-19)30(3,28)29)11-12-27(21)14-17-7-9-18(10-8-17)22(23,24)25/h4-6,13,16-18,21H,7-12,14-15H2,1-3H3/t17?,18?,21-/m1/s1 QMWLHYCYYOVUQE-WIXQSORDSA-N 304670 (2S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)piperidin-3-yl)methyl)piperazine::US10144715, Compound 48-68 Oxysterols receptor LXR-beta 179 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304670&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883485 381753375 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584266 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@]3(CC3(F)F)CC2)[C@H](C1)c1ccccc1 InChI=1S/C26H32F2N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)21-6-3-2-4-7-21)17-20-10-12-25(13-11-20)19-26(25,27)28/h2-9,16,20,24H,10-15,17-19H2,1H3/t20-,24-,25+/m1/s1 KQGULCLQMZRZGO-ZPZUNKDASA-N 304671 (S)-1-(((3R,6s)-1,1-difluorospiro[2.5]octan-6-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-69 Oxysterols receptor LXR-beta 14.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304671&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883514 381753376 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584267 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@]3(CC3(F)F)CC2)[C@@H](C1)c1ccccc1 InChI=1S/C26H32F2N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)21-6-3-2-4-7-21)17-20-10-12-25(13-11-20)19-26(25,27)28/h2-9,16,20,24H,10-15,17-19H2,1H3/t20-,24-,25+/m0/s1 KQGULCLQMZRZGO-KSNOWIBYSA-N 304672 (R)-1-(((3S,6s)-1,1-difluorospiro[2.5]octan-6-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-70 Oxysterols receptor LXR-beta 750 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304672&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883517 381753377 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584269 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@@]3(CC3(F)F)CC2)[C@H](C1)c1ccccc1 InChI=1S/C26H32F2N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)21-6-3-2-4-7-21)17-20-10-12-25(13-11-20)19-26(25,27)28/h2-9,16,20,24H,10-15,17-19H2,1H3/t20-,24-,25-/m1/s1 KQGULCLQMZRZGO-NIJXNBFTSA-N 304673 (S)-1-(((3S,6r)-1,1-difluorospiro[2.5]octan-6-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-71 Oxysterols receptor LXR-beta 10.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304673&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883514 381753378 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584270 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@@]3(CC3(F)F)CC2)[C@@H](C1)c1ccccc1 InChI=1S/C26H32F2N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)21-6-3-2-4-7-21)17-20-10-12-25(13-11-20)19-26(25,27)28/h2-9,16,20,24H,10-15,17-19H2,1H3/t20-,24-,25-/m0/s1 KQGULCLQMZRZGO-OPXMRZJTSA-N 304674 (R)-1-(((3R,6r)-1,1-difluorospiro[2.5]octan-6-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 48-72 Oxysterols receptor LXR-beta 825 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304674&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883517 381753379 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584272 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCC(O2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C23H26F4N2O3S/c1-33(30,31)20-4-2-3-18(13-20)28-11-12-29(14-19-9-10-22(32-19)23(25,26)27)21(15-28)16-5-7-17(24)8-6-16/h2-8,13,19,21-22H,9-12,14-15H2,1H3/t19?,21-,22?/m1/s1 AWZGAOQRIVTAJV-NJEKYYFSSA-N 304675 (2S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((5-(trifluoromethyl)tetrahydrofuran-2-yl)methyl)piperazine::US10144715, Compound 48-73 Oxysterols receptor LXR-beta 283 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304675&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883520 381753380 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584274 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CCC(O2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C23H26F4N2O3S/c1-33(30,31)20-4-2-3-18(13-20)28-11-12-29(14-19-9-10-22(32-19)23(25,26)27)21(15-28)16-5-7-17(24)8-6-16/h2-8,13,19,21-22H,9-12,14-15H2,1H3/t19-,21-,22?/m1/s1 AWZGAOQRIVTAJV-ZJBPFHOOSA-N 304676 (2S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((5-(trifluoromethyl)tetrahydrofuran-2-yl)methyl)piperazine::US10144715, Compound 48-74 Oxysterols receptor LXR-beta 2011 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304676&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554639 381753381 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584275 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2C[C@@H]3CC[C@H](C2)N3CC(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C27H34F3N3O2S/c1-36(34,35)25-9-5-8-22(16-25)31-12-13-32(26(18-31)21-6-3-2-4-7-21)17-20-14-23-10-11-24(15-20)33(23)19-27(28,29)30/h2-9,16,20,23-24,26H,10-15,17-19H2,1H3/t20-,23+,24-,26-/m0/s1 GUMMCCUCZHGLRT-OKJKUSBXSA-N 304677 (1R,3s,5S)-3-(((R)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)-8-(2,2,2-trifluoroethyl)-8-azabicyclo[3.2.1]octane::US10144715, Compound 48-75 Oxysterols receptor LXR-beta 940 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304677&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883518 381753382 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584276 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2C[C@@H]3CC[C@H](C2)N3CC(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C27H34F3N3O2S/c1-36(34,35)25-9-5-8-22(16-25)31-12-13-32(26(18-31)21-6-3-2-4-7-21)17-20-14-23-10-11-24(15-20)33(23)19-27(28,29)30/h2-9,16,20,23-24,26H,10-15,17-19H2,1H3/t20-,23+,24-,26-/m1/s1 GUMMCCUCZHGLRT-JOXZGHKQSA-N 304678 (1R,3s,5S)-3-(((S)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)-8-(2,2,2-trifluoroethyl)-8-azabicyclo[3.2.1]octane::US10144715, Compound 48-76 Oxysterols receptor LXR-beta 67.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304678&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883546 381753383 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584278 CC(C)[C@H]1CCC(CC1)C(=O)N1CCN(C[C@@H]1c1ccccc1)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C29H40N2O4S/c1-21(2)22-9-11-25(12-10-22)29(33)31-17-16-30(20-27(31)23-7-5-4-6-8-23)26-14-13-24(15-18-32)28(19-26)36(3,34)35/h4-8,13-14,19,21-22,25,27,32H,9-12,15-18,20H2,1-3H3/t22-,25?,27-/m1/s1 HXTCYOBQTHVZMG-QLOWOONCSA-N 304679 (4-((S)-4-(((1r,4S)-4-isopropylcyclohexyl)methyl)-3-phenylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-77 Oxysterols receptor LXR-beta 23.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304679&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554640 381753384 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584280 CC(C)[C@H]1CCC(CC1)C(=O)N1CCN(C[C@H]1c1ccccc1)c1ccc(CCO)c(c1)S(C)(=O)=O InChI=1S/C29H40N2O4S/c1-21(2)22-9-11-25(12-10-22)29(33)31-17-16-30(20-27(31)23-7-5-4-6-8-23)26-14-13-24(15-18-32)28(19-26)36(3,34)35/h4-8,13-14,19,21-22,25,27,32H,9-12,15-18,20H2,1-3H3/t22-,25?,27-/m0/s1 HXTCYOBQTHVZMG-UMQIIANQSA-N 304680 (4-((R)-4-(((1r,4R)-4-isopropylcyclohexyl)methyl)-3-phenylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-78 Oxysterols receptor LXR-beta 2461 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304680&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554641 381753385 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584282 CO[C@]1(CC[C@H](CN2CCN(C[C@@H]2C(C)C)c2ccc(CO)c(c2)S(C)(=O)=O)CC1)C(F)(F)F InChI=1S/C24H37F3N2O4S/c1-17(2)21-15-28(20-6-5-19(16-30)22(13-20)34(4,31)32)11-12-29(21)14-18-7-9-23(33-3,10-8-18)24(25,26)27/h5-6,13,17-18,21,30H,7-12,14-16H2,1-4H3/t18-,21-,23-/m1/s1 GARJJUDIJXDOGG-JMUQELJHSA-N 304681 (4-((S)-3-isopropyl-4-(((1r,4S)-4-methoxy-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-79 Oxysterols receptor LXR-beta 2.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304681&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883549 381753386 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584284 CO[C@@]1(CC[C@H](CN2CCN(C[C@@H]2C(C)C)c2ccc(CO)c(c2)S(C)(=O)=O)CC1)C(F)(F)F InChI=1S/C24H37F3N2O4S/c1-17(2)21-15-28(20-6-5-19(16-30)22(13-20)34(4,31)32)11-12-29(21)14-18-7-9-23(33-3,10-8-18)24(25,26)27/h5-6,13,17-18,21,30H,7-12,14-16H2,1-4H3/t18-,21-,23+/m1/s1 GARJJUDIJXDOGG-AAIMPIBUSA-N 304682 (4-((S)-3-isopropyl-4-(((1s,4R)-4-methoxy-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-80 Oxysterols receptor LXR-beta 3.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304682&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883549 381753387 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584286 NS(=O)(=O)c1cccc(c1)N1CCN(CC2CCN(CC(F)(F)F)CC2)[C@H](C1)c1ccccc1 InChI=1S/C24H31F3N4O2S/c25-24(26,27)18-29-11-9-19(10-12-29)16-31-14-13-30(17-23(31)20-5-2-1-3-6-20)21-7-4-8-22(15-21)34(28,32)33/h1-8,15,19,23H,9-14,16-18H2,(H2,28,32,33)/t23-/m1/s1 YEFVPXATHXOZEA-HSZRJFAPSA-N 304683 (S)-3-(3-phenyl-4-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-81 Oxysterols receptor LXR-beta 479 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304683&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554642 381753388 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584288 NS(=O)(=O)c1cccc(c1)N1CCN(CC2CCN(CC(F)(F)F)CC2)[C@@H](C1)c1ccccc1 InChI=1S/C24H31F3N4O2S/c25-24(26,27)18-29-11-9-19(10-12-29)16-31-14-13-30(17-23(31)20-5-2-1-3-6-20)21-7-4-8-22(15-21)34(28,32)33/h1-8,15,19,23H,9-14,16-18H2,(H2,28,32,33)/t23-/m0/s1 YEFVPXATHXOZEA-QHCPKHFHSA-N 304684 (R)-3-(3-phenyl-4-((1-(2,2,2-trifluoroethyl)piperidin-4-yl)methyl)piperazin-1-yl)benzenesulfonamide::US10144715, Compound 48-82 Oxysterols receptor LXR-beta 2487 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304684&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554643 381753389 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584290 CC(C)[C@H]1CN(CCN1C[C@H]1CC[C@H](OC1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C22H33F3N2O4S/c1-15(2)19-12-26(18-6-5-17(13-28)20(10-18)32(3,29)30)8-9-27(19)11-16-4-7-21(31-14-16)22(23,24)25/h5-6,10,15-16,19,21,28H,4,7-9,11-14H2,1-3H3/t16-,19-,21+/m1/s1 PYIUJPJVIHJOFC-BSIFCXSSSA-N 304685 (4-((S)-3-isopropyl-4-(((3R,6S)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 49-1 Oxysterols receptor LXR-beta 37.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304685&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872020 381753390 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584292 CC(C)[C@H]1CN(CCN1C[C@H]1CC[C@@H](OC1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C22H33F3N2O4S/c1-15(2)19-12-26(18-6-5-17(13-28)20(10-18)32(3,29)30)8-9-27(19)11-16-4-7-21(31-14-16)22(23,24)25/h5-6,10,15-16,19,21,28H,4,7-9,11-14H2,1-3H3/t16-,19-,21-/m1/s1 PYIUJPJVIHJOFC-OZOXKJRCSA-N 304686 (4-((S)-3-isopropyl-4-(((3R,6R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 49-2 Oxysterols receptor LXR-beta 23.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304686&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872056 381753391 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584294 CC(C)[C@H]1CN(CCN1C[C@@H]1CC[C@H](OC1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C22H33F3N2O4S/c1-15(2)19-12-26(18-6-5-17(13-28)20(10-18)32(3,29)30)8-9-27(19)11-16-4-7-21(31-14-16)22(23,24)25/h5-6,10,15-16,19,21,28H,4,7-9,11-14H2,1-3H3/t16-,19+,21-/m0/s1 PYIUJPJVIHJOFC-SCWSEQNSSA-N 304687 (4-((S)-3-isopropyl-4-(((3S,6S)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 49-3 Oxysterols receptor LXR-beta 17.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304687&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872116 381753392 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584296 CC(C)[C@H]1CN(CCN1C[C@@H]1CC[C@@H](OC1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C22H33F3N2O4S/c1-15(2)19-12-26(18-6-5-17(13-28)20(10-18)32(3,29)30)8-9-27(19)11-16-4-7-21(31-14-16)22(23,24)25/h5-6,10,15-16,19,21,28H,4,7-9,11-14H2,1-3H3/t16-,19+,21+/m0/s1 PYIUJPJVIHJOFC-LDQXTDLNSA-N 304688 (4-((S)-3-isopropyl-4-(((3S,6R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 49-4::US10144715, Compound 49-5 Oxysterols receptor LXR-beta 7.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304688&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872022 381753393 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584298 CC(C)[C@H]1CN(CCN1C[C@@H]1CC[C@@H](OC1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C22H33F3N2O4S/c1-15(2)19-12-26(18-6-5-17(13-28)20(10-18)32(3,29)30)8-9-27(19)11-16-4-7-21(31-14-16)22(23,24)25/h5-6,10,15-16,19,21,28H,4,7-9,11-14H2,1-3H3/t16-,19+,21+/m0/s1 PYIUJPJVIHJOFC-LDQXTDLNSA-N 304688 (4-((S)-3-isopropyl-4-(((3S,6R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 49-4::US10144715, Compound 49-5 Oxysterols receptor LXR-beta 70.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304688&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872022 381753393 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583486 CC(C)(C)OC(=O)N1CCN(CC1C1CCCCC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H34N2O4S/c1-22(2,3)28-21(25)24-14-13-23(16-20(24)17-9-6-5-7-10-17)18-11-8-12-19(15-18)29(4,26)27/h8,11-12,15,17,20H,5-7,9-10,13-14,16H2,1-4H3 LWRFHACDWCRBQQ-UHFFFAOYSA-N 304298 US10144715, Compound 1-11::tert-butyl 2-cyclohexyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 340 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304298&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554386 381753013 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583488 CC(C)(C)OC(=O)N1CCN(CC1c1ccc(Br)cc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H27BrN2O4S/c1-22(2,3)29-21(26)25-13-12-24(15-20(25)16-8-10-17(23)11-9-16)18-6-5-7-19(14-18)30(4,27)28/h5-11,14,20H,12-13,15H2,1-4H3 BWDVFZSNKBBPGB-UHFFFAOYSA-N 304299 US10144715, Compound 1-12::tert-butyl 2-(4-bromophenyl)-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 81.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554387 381753014 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583490 CCC(C)[C@@H]1CN(CCN1Cc1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H30N2O2S/c1-4-18(2)22-17-23(20-11-8-12-21(15-20)27(3,25)26)13-14-24(22)16-19-9-6-5-7-10-19/h5-12,15,18,22H,4,13-14,16-17H2,1-3H3/t18?,22-/m0/s1 RCUJWQHUVDWKFQ-YSYXNDDBSA-N 304300 US10144715, Compound 1-13::benzyl (R)-2-isobutyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 36.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304300&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554388 381753015 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583492 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccccc2)C(C1)c1ccccc1 InChI=1S/C24H26N2O2S/c1-29(27,28)23-14-8-13-22(17-23)25-15-16-26(18-20-9-4-2-5-10-20)24(19-25)21-11-6-3-7-12-21/h2-14,17,24H,15-16,18-19H2,1H3 JJJWPNKCBQSHHN-UHFFFAOYSA-N 304301 BDBM304540::US10144715, Compound 1-14::benzyl 4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 192 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304301&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554389 381753016 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583493 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H29FN2O4S/c1-13(2)16-12-21(9-10-22(16)18(23)26-19(3,4)5)14-7-8-15(20)17(11-14)27(6,24)25/h7-8,11,13,16H,9-10,12H2,1-6H3/t16-/m0/s1 HMYASRGTOBBXDF-INIZCTEOSA-N 304302 US10144715, Compound 2-1::tert-butyl (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 209 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304302&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883428 381753017 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583495 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H29FN2O4S/c1-13(2)16-12-21(9-10-22(16)18(23)26-19(3,4)5)14-7-8-15(20)17(11-14)27(6,24)25/h7-8,11,13,16H,9-10,12H2,1-6H3/t16-/m0/s1 HMYASRGTOBBXDF-INIZCTEOSA-N 304302 US10144715, Compound 2-1::tert-butyl (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 56.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304302&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883428 381753017 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583497 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H30N2O4S/c1-14(2)17-13-20(10-11-21(17)18(22)25-19(3,4)5)15-8-7-9-16(12-15)26(6,23)24/h7-9,12,14,17H,10-11,13H2,1-6H3/t17-/m0/s1 HDOWNKAPIXMAAE-KRWDZBQOSA-N 304288 US10144715, Compound 1-1::US10144715, Compound 2-2::tert-butyl (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 1926 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883536 381753003 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583500 COC(=O)c1ccc(cc1S(C)(=O)=O)N1CCN([C@H](C1)c1ccccc1)C(=O)OC(C)(C)C InChI=1S/C24H30N2O6S/c1-24(2,3)32-23(28)26-14-13-25(16-20(26)17-9-7-6-8-10-17)18-11-12-19(22(27)31-4)21(15-18)33(5,29)30/h6-12,15,20H,13-14,16H2,1-5H3/t20-/m1/s1 PVPDTJJRMVZWGW-HXUWFJFHSA-N 304304 US10144715, Compound 2-3::tert-butyl 4-(4-(methoxycarbonyl)-3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 1143 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304304&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554390 381753018 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583502 CCOC(=O)c1csc(n1)C1CN(CCN1C(=O)OC(C)(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H28FN3O6S2/c1-6-31-20(27)16-13-33-19(24-16)17-12-25(9-10-26(17)21(28)32-22(2,3)4)14-7-8-15(23)18(11-14)34(5,29)30/h7-8,11,13,17H,6,9-10,12H2,1-5H3 BWOOPIORPKRUNE-UHFFFAOYSA-N 304305 US10144715, Compound 2-4::ethyl (R)-2-(4-(4-(tert-butoxycarbonyl)-3-isopropylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)thiazole-4-carboxylate Oxysterols receptor LXR-beta 197 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304305&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554391 381753019 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583504 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C20H29N3O4S/c1-14(2)17-13-22(9-10-23(17)19(24)27-20(3,4)5)16-8-7-15(12-21)18(11-16)28(6,25)26/h7-8,11,14,17H,9-10,13H2,1-6H3/t17-/m0/s1 JLYQRFAJCOZVOL-KRWDZBQOSA-N 304306 US10144715, Compound 3-1::tert-butyl (R)-4-(4-cyano-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 618 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304306&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883488 381753020 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583506 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1ccc(-c2ccc(cc2)C(F)(F)F)c(c1)S(C)(=O)=O InChI=1S/C26H33F3N2O4S/c1-17(2)22-16-30(13-14-31(22)24(32)35-25(3,4)5)20-11-12-21(23(15-20)36(6,33)34)18-7-9-19(10-8-18)26(27,28)29/h7-12,15,17,22H,13-14,16H2,1-6H3/t22-/m0/s1 STUFDWLFVDUQDM-QFIPXVFZSA-N 304307 US10144715, Compound 3-2::tert-butyl (R)-2-isopropyl-4-(3-(methylsulfonyl)-4-(trifluoromethyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 931 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304307&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554392 381753021 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583508 CC(C)[C@H]1CN(CCN1c1ncc(c(C)n1)S(C)(=O)=O)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H27FN4O4S2/c1-13(2)17-12-24(15-6-7-16(21)18(10-15)30(4,26)27)8-9-25(17)20-22-11-19(14(3)23-20)31(5,28)29/h6-7,10-11,13,17H,8-9,12H2,1-5H3/t17-/m1/s1 DITLDIMUMXZLSV-QGZVFWFLSA-N 304308 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methyl-5-(methylsulfonyl)pyrimidine::US10144715, Compound 3-3 Oxysterols receptor LXR-beta 288 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304308&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554393 381753022 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583510 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1ccc(C(N)=O)c(c1)S(C)(=O)=O InChI=1S/C20H31N3O5S/c1-13(2)16-12-22(9-10-23(16)19(25)28-20(3,4)5)14-7-8-15(18(21)24)17(11-14)29(6,26)27/h7-8,11,13,16H,9-10,12H2,1-6H3,(H2,21,24)/t16-/m0/s1 JPNIOWQIXBXIBX-INIZCTEOSA-N 304309 US10144715, Compound 4-1::tert-butyl (R)-4-(4-carbamoyl-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 2410 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304309&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883489 381753023 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583513 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(C(N)=O)c(c1Cl)S(C)(=O)=O InChI=1S/C20H23ClF3N5O3S/c1-11(2)14-10-28(8-9-29(14)19-26-7-6-15(27-19)20(22,23)24)13-5-4-12(18(25)30)17(16(13)21)33(3,31)32/h4-7,11,14H,8-10H2,1-3H3,(H2,25,30)/t14-/m0/s1 PISJKDSISKAUFY-AWEZNQCLSA-N 304311 (R)-3-chloro-4-(3-isopropyl-4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)benzamide::US10144715, Compound 4-3 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304311&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554395 381753025 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583515 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cc(c(cc1Cl)C(N)=O)S(C)(=O)=O InChI=1S/C20H23ClF3N5O3S/c1-11(2)15-10-28(6-7-29(15)19-26-5-4-17(27-19)20(22,23)24)14-9-16(33(3,31)32)12(18(25)30)8-13(14)21/h4-5,8-9,11,15H,6-7,10H2,1-3H3,(H2,25,30)/t15-/m0/s1 GTEXICSUUJWQPY-HNNXBMFYSA-N 304312 (R)-5-chloro-4-(3-isopropyl-4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)benzamide::US10144715, Compound 4-4 Oxysterols receptor LXR-beta 1630 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304312&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554396 381753026 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583517 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(N)=O)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H24FN5O3S/c1-12(2)16-11-24(13-4-5-14(20)17(10-13)29(3,27)28)8-9-25(16)19-22-7-6-15(23-19)18(21)26/h4-7,10,12,16H,8-9,11H2,1-3H3,(H2,21,26)/t16-/m0/s1 FZRJTNPDLMVCEC-INIZCTEOSA-N 304313 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyrimidine-4-carboxamide::US10144715, Compound 4-5 Oxysterols receptor LXR-beta 495 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304313&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554397 381753027 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583519 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(N)=O)c1ccc(C(O)=O)c(c1)S(C)(=O)=O InChI=1S/C20H25N5O5S/c1-12(2)16-11-24(8-9-25(16)20-22-7-6-15(23-20)18(21)26)13-4-5-14(19(27)28)17(10-13)31(3,29)30/h4-7,10,12,16H,8-9,11H2,1-3H3,(H2,21,26)(H,27,28)/t16-/m0/s1 BLERRDGECJBKCH-INIZCTEOSA-N 304314 (R)-4-(4-(4-(hydroxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)picolinamide::US10144715, Compound 4-6 Oxysterols receptor LXR-beta 936 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304314&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554398 381753028 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583521 CC(C)[C@@H]1CN(CCN1c1ncc(c(n1)C(N)=O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23F4N5O3S/c1-11(2)15-10-28(12-4-5-14(21)16(8-12)33(3,31)32)6-7-29(15)19-26-9-13(20(22,23)24)17(27-19)18(25)30/h4-5,8-9,11,15H,6-7,10H2,1-3H3,(H2,25,30)/t15-/m0/s1 MOLPHGVUKWQWMX-HNNXBMFYSA-N 304315 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyrimidine-4-carboxamide::US10144715, Compound 4-7 Oxysterols receptor LXR-beta 173 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304315&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554399 381753029 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583523 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1Cl InChI=1S/C26H31ClF3N3O3S/c1-37(35,36)24-14-19(10-11-21(24)25(31)34)32-12-13-33(23(16-32)20-4-2-3-5-22(20)27)15-17-6-8-18(9-7-17)26(28,29)30/h2-5,10-11,14,17-18,23H,6-9,12-13,15-16H2,1H3,(H2,31,34)/t17-,18+,23-/m1/s1 FMOAGFUWAWYZBQ-IEGUWTFLSA-N 304316 4-((S)-3-(2-chlorophenyl)-4-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)benzamide::US10144715, Compound 4-8 Oxysterols receptor LXR-beta 80.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304316&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883490 381753030 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583525 CS(=O)(=O)c1cc(ccc1C(N)=O)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@@H](C1)c1ccccc1Cl InChI=1S/C26H31ClF3N3O3S/c1-37(35,36)24-14-19(10-11-21(24)25(31)34)32-12-13-33(23(16-32)20-4-2-3-5-22(20)27)15-17-6-8-18(9-7-17)26(28,29)30/h2-5,10-11,14,17-18,23H,6-9,12-13,15-16H2,1H3,(H2,31,34)/t17-,18+,23-/m0/s1 FMOAGFUWAWYZBQ-IXFSTUDKSA-N 304317 4-((R)-3-(2-chlorophenyl)-4-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)benzamide::US10144715, Compound 4-9 Oxysterols receptor LXR-beta 926 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304317&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883491 381753031 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583527 CC(C)[C@@H]1CN(CCN1C(=O)OC1CC(F)(F)C1(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H23F5N2O4S/c1-11(2)14-10-25(12-4-5-13(20)15(8-12)31(3,28)29)6-7-26(14)17(27)30-16-9-18(21,22)19(16,23)24/h4-5,8,11,14,16H,6-7,9-10H2,1-3H3/t14-,16?/m0/s1 JMPXRXGCUIOVIQ-LBAUFKAWSA-N 304318 2,2,3,3-tetrafluorocyclobutyl (2R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate::US10144715, Compound 5-1 Oxysterols receptor LXR-beta 54.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304318&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883439 381753032 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583529 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H26F4N2O4S/c1-12(2)15-11-24(13-6-7-14(20)16(10-13)30(5,27)28)8-9-25(15)17(26)29-18(3,4)19(21,22)23/h6-7,10,12,15H,8-9,11H2,1-5H3/t15-/m0/s1 VIEODBHSIYUQTK-HNNXBMFYSA-N 304319 1,1,1-trifluoro-2-methylpropan-2-yl (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate::US10144715, Compound 5-2 Oxysterols receptor LXR-beta 15.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304319&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554400 381753033 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583531 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C18H24F4N2O4S/c1-11(2)15-10-23(13-5-6-14(19)16(9-13)29(4,26)27)7-8-24(15)17(25)28-12(3)18(20,21)22/h5-6,9,11-12,15H,7-8,10H2,1-4H3/t12?,15-/m0/s1 BCYNXJGQHVLDNU-CVRLYYSRSA-N 304320 1,1,1-trifluoropropan-2-yl (2R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate::US10144715, Compound 5-3 Oxysterols receptor LXR-beta 38.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304320&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554401 381753034 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583533 CC(C)[C@@H]1CN(CCN1C(=O)OCC(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C17H22F4N2O4S/c1-11(2)14-9-22(6-7-23(14)16(24)27-10-17(19,20)21)12-4-5-13(18)15(8-12)28(3,25)26/h4-5,8,11,14H,6-7,9-10H2,1-3H3/t14-/m0/s1 DUDVEIHNPZPOOF-AWEZNQCLSA-N 304321 2,2,2-trifluoroethyl (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine-1-carboxylate::US10144715, Compound 5-4 Oxysterols receptor LXR-beta 290 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304321&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554402 381753035 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583535 CCC(C)OC(=O)N1CCN(CC1c1ccccc1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H27FN2O4S/c1-4-16(2)29-22(26)25-13-12-24(15-20(25)17-8-6-5-7-9-17)18-10-11-19(23)21(14-18)30(3,27)28/h5-11,14,16,20H,4,12-13,15H2,1-3H3 XZKOOUXHUVKWQX-UHFFFAOYSA-N 304322 US10144715, Compound 5-5::isobutyl 4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 76.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304322&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554403 381753036 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584300 CC(C)[C@H]1CN(CCN1C[C@H]1CC[C@@H](OC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H31F3N2O3S/c1-15(2)19-13-25(17-5-4-6-18(11-17)30(3,27)28)9-10-26(19)12-16-7-8-20(29-14-16)21(22,23)24/h4-6,11,15-16,19-20H,7-10,12-14H2,1-3H3/t16-,19-,20-/m1/s1 GEXZSCVAMWWQAV-NSISKUIASA-N 304690 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((3R,6R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 49-6 Oxysterols receptor LXR-beta 46.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304690&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883554 381753394 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584302 CC(C)[C@H]1CN(CCN1C[C@@H]1CC[C@H](OC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H31F3N2O3S/c1-15(2)19-13-25(17-5-4-6-18(11-17)30(3,27)28)9-10-26(19)12-16-7-8-20(29-14-16)21(22,23)24/h4-6,11,15-16,19-20H,7-10,12-14H2,1-3H3/t16-,19+,20-/m0/s1 GEXZSCVAMWWQAV-DBVUQKKJSA-N 304691 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((3S,6S)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 49-7 Oxysterols receptor LXR-beta 45.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304691&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883557 381753395 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584304 CC(C)[C@H]1CN(CCN1C[C@@H]1CC[C@@H](OC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H31F3N2O3S/c1-15(2)19-13-25(17-5-4-6-18(11-17)30(3,27)28)9-10-26(19)12-16-7-8-20(29-14-16)21(22,23)24/h4-6,11,15-16,19-20H,7-10,12-14H2,1-3H3/t16-,19+,20+/m0/s1 GEXZSCVAMWWQAV-PWIZWCRZSA-N 304692 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(((3S,6R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 49-8 Oxysterols receptor LXR-beta 11.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304692&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883553 381753396 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584306 CS(=O)(=O)c1cc(ccc1CO)N1CCN(C[C@@H]2CC[C@@H](OC2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C25H30F4N2O4S/c1-36(33,34)23-12-21(8-5-19(23)15-32)30-10-11-31(22(14-30)18-3-6-20(26)7-4-18)13-17-2-9-24(35-16-17)25(27,28)29/h3-8,12,17,22,24,32H,2,9-11,13-16H2,1H3/t17-,22+,24+/m0/s1 BUCFYSDKVCCYDP-VXWZWFMZSA-N 304693 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((3R,6S)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 49-9 Oxysterols receptor LXR-beta 150 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304693&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554644 381753397 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584308 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@H]2CC[C@@H](OC2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C24H28F4N2O3S/c1-34(31,32)21-4-2-3-20(13-21)29-11-12-30(22(15-29)18-6-8-19(25)9-7-18)14-17-5-10-23(33-16-17)24(26,27)28/h2-4,6-9,13,17,22-23H,5,10-12,14-16H2,1H3/t17-,22-,23-/m1/s1 ISUZFVXNJCGBJL-NLSFWIRASA-N 304694 (2S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((3R)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 49-10 Oxysterols receptor LXR-beta 53.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304694&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554645 381753398 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584310 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2CC[C@@H](OC2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C24H28F4N2O3S/c1-34(31,32)21-4-2-3-20(13-21)29-11-12-30(22(15-29)18-6-8-19(25)9-7-18)14-17-5-10-23(33-16-17)24(26,27)28/h2-4,6-9,13,17,22-23H,5,10-12,14-16H2,1H3/t17-,22+,23+/m0/s1 ISUZFVXNJCGBJL-JJEOQYAHSA-N 304695 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((3S,6S)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::BDBM304696::US10144715, Compound 49-11 Oxysterols receptor LXR-beta 214 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304695&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554646 381753399 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584312 CS(=O)(=O)c1cccc(c1)N1CCN(C[C@@H]2CC[C@@H](OC2)C(F)(F)F)[C@H](C1)c1ccc(F)cc1 InChI=1S/C24H28F4N2O3S/c1-34(31,32)21-4-2-3-20(13-21)29-11-12-30(22(15-29)18-6-8-19(25)9-7-18)14-17-5-10-23(33-16-17)24(26,27)28/h2-4,6-9,13,17,22-23H,5,10-12,14-16H2,1H3/t17-,22+,23+/m0/s1 ISUZFVXNJCGBJL-JJEOQYAHSA-N 304695 (S)-2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-(((3S,6S)-6-(trifluoromethyl)tetrahydro-2H-pyran-3-yl)methyl)piperazine::BDBM304696::US10144715, Compound 49-11 Oxysterols receptor LXR-beta 184 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304695&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554646 381753399 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584314 CC(C)[C@H]1CN(CCN1C[C@H]1CC[C@H](CC1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C23H32F3N3O2S/c1-16(2)21-15-28(20-9-6-18(13-27)22(12-20)32(3,30)31)10-11-29(21)14-17-4-7-19(8-5-17)23(24,25)26/h6,9,12,16-17,19,21H,4-5,7-8,10-11,14-15H2,1-3H3/t17-,19+,21-/m1/s1 WLYJUBOVJNVBDO-SLYNCCJLSA-N 304697 4-((S)-3-isopropyl-4-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 50-1 Oxysterols receptor LXR-beta 6.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304697&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872123 381753401 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584316 CC(C)[C@H]1CN(CCN1C[C@H]1CC[C@H](CC1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C23H32F3N3O2S/c1-16(2)21-15-28(20-9-6-18(13-27)22(12-20)32(3,30)31)10-11-29(21)14-17-4-7-19(8-5-17)23(24,25)26/h6,9,12,16-17,19,21H,4-5,7-8,10-11,14-15H2,1-3H3/t17-,19+,21-/m1/s1 WLYJUBOVJNVBDO-SLYNCCJLSA-N 304698 4-((S)-3-isopropyl-4-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 50-2 Oxysterols receptor LXR-beta 51.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304698&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872123 381753402 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584318 CS(=O)(=O)c1cc(ccc1C#N)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C26H30F3N3O2S/c1-35(33,34)25-15-23(12-9-21(25)16-30)31-13-14-32(24(18-31)20-5-3-2-4-6-20)17-19-7-10-22(11-8-19)26(27,28)29/h2-6,9,12,15,19,22,24H,7-8,10-11,13-14,17-18H2,1H3/t19-,22+,24-/m0/s1 WWWVODUMLXMIRV-KWOQKUFVSA-N 304699 2-(methylsulfonyl)-4-((R)-3-phenyl-4-(((1r,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzonitrile::US10144715, Compound 50-3 Oxysterols receptor LXR-beta 1663 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304699&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554647 381753403 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584320 CS(=O)(=O)c1cc(ccc1C#N)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C26H30F3N3O2S/c1-35(33,34)25-15-23(12-9-21(25)16-30)31-13-14-32(24(18-31)20-5-3-2-4-6-20)17-19-7-10-22(11-8-19)26(27,28)29/h2-6,9,12,15,19,22,24H,7-8,10-11,13-14,17-18H2,1H3/t19-,22+,24-/m1/s1 WWWVODUMLXMIRV-WNOPAQSVSA-N 304700 2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzonitrile::US10144715, Compound 50-4 Oxysterols receptor LXR-beta 516 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304700&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554648 381753404 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584322 CS(=O)(=O)c1cc(ccc1C#N)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C26H30F3N3O2S/c1-35(33,34)25-15-23(12-9-21(25)16-30)31-13-14-32(24(18-31)20-5-3-2-4-6-20)17-19-7-10-22(11-8-19)26(27,28)29/h2-6,9,12,15,19,22,24H,7-8,10-11,13-14,17-18H2,1H3/t19-,22+,24-/m1/s1 WWWVODUMLXMIRV-WNOPAQSVSA-N 304700 2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzonitrile::US10144715, Compound 50-4 Oxysterols receptor LXR-beta 1630 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304700&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554648 381753404 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584324 CS(=O)(=O)c1cc(ccc1C#N)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C26H30F3N3O2S/c1-35(33,34)25-15-23(12-9-21(25)16-30)31-13-14-32(24(18-31)20-5-3-2-4-6-20)17-19-7-10-22(11-8-19)26(27,28)29/h2-6,9,12,15,19,22,24H,7-8,10-11,13-14,17-18H2,1H3/t19-,22+,24-/m0/s1 WWWVODUMLXMIRV-KWOQKUFVSA-N 304701 2-(methylsulfonyl)-4-((R)-3-phenyl-4-(((1s,4S)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzonitrile::US10144715, Compound 50-5 Oxysterols receptor LXR-beta 688 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304701&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554647 381753405 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584326 CS(=O)(=O)c1cc(ccc1C#N)N1CCN(C[C@H]2CC[C@H](CC2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C26H30F3N3O2S/c1-35(33,34)25-15-23(12-9-21(25)16-30)31-13-14-32(24(18-31)20-5-3-2-4-6-20)17-19-7-10-22(11-8-19)26(27,28)29/h2-6,9,12,15,19,22,24H,7-8,10-11,13-14,17-18H2,1H3/t19-,22+,24-/m1/s1 WWWVODUMLXMIRV-WNOPAQSVSA-N 304702 2-(methylsulfonyl)-4-((S)-3-phenyl-4-(((1s,4R)-4-(trifluoromethyl)cyclohexyl)methyl)piperazin-1-yl)benzonitrile::US10144715, Compound 50-6 Oxysterols receptor LXR-beta 58.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554648 381753406 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584328 CC(C)[C@H]1CN(CCN1CC1CCCOC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H32N2O3S/c1-16(2)20-14-21(18-7-4-8-19(12-18)26(3,23)24)9-10-22(20)13-17-6-5-11-25-15-17/h4,7-8,12,16-17,20H,5-6,9-11,13-15H2,1-3H3/t17?,20-/m1/s1 MQWCKKGSGDWVJV-UUSAFJCLSA-N 304703 (2S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-((tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 51-1 Oxysterols receptor LXR-beta 1533 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304703&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872087 381753407 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584330 CC(C)[C@H]1CN(CCN1CC1CCOCC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H32N2O3S/c1-16(2)20-15-21(18-5-4-6-19(13-18)26(3,23)24)9-10-22(20)14-17-7-11-25-12-8-17/h4-6,13,16-17,20H,7-12,14-15H2,1-3H3/t20-/m1/s1 FEGKBRSPMOULKP-HXUWFJFHSA-N 304704 (S)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-((tetrahydro-2H-pyran-4-yl)methyl)piperazine::US10144715, Compound 51-2 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304704&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554649 381753408 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584332 CC(C)[C@H]1CN(CCN1CC1CCC(C)(C)OC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H36N2O3S/c1-17(2)21-15-23(19-7-6-8-20(13-19)28(5,25)26)11-12-24(21)14-18-9-10-22(3,4)27-16-18/h6-8,13,17-18,21H,9-12,14-16H2,1-5H3/t18?,21-/m1/s1 GPJOZMPVGWSUGN-BDPMCISCSA-N 304705 (2S)-1-((6,6-dimethyltetrahydro-2H-pyran-3-yl)methyl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 51-3 Oxysterols receptor LXR-beta 482 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304705&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554650 381753409 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584334 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCCOC2)[C@H](C1)c1ccccc1 InChI=1S/C23H30N2O3S/c1-29(26,27)22-11-5-10-21(15-22)24-12-13-25(16-19-7-6-14-28-18-19)23(17-24)20-8-3-2-4-9-20/h2-5,8-11,15,19,23H,6-7,12-14,16-18H2,1H3/t19?,23-/m1/s1 LEPONXRYEHRCTC-LEQGEALCSA-N 304706 (2S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 51-4 Oxysterols receptor LXR-beta 546 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304706&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554651 381753410 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584336 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCCOC2)[C@H](C1)c1ccccc1 InChI=1S/C23H30N2O3S/c1-29(26,27)22-11-5-10-21(15-22)24-12-13-25(16-19-7-6-14-28-18-19)23(17-24)20-8-3-2-4-9-20/h2-5,8-11,15,19,23H,6-7,12-14,16-18H2,1H3/t19?,23-/m1/s1 LEPONXRYEHRCTC-LEQGEALCSA-N 304706 (2S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((tetrahydro-2H-pyran-3-yl)methyl)piperazine::US10144715, Compound 51-4 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304706&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554651 381753410 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584338 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCOCC2)[C@H](C1)c1ccccc1 InChI=1S/C23H30N2O3S/c1-29(26,27)22-9-5-8-21(16-22)24-12-13-25(17-19-10-14-28-15-11-19)23(18-24)20-6-3-2-4-7-20/h2-9,16,19,23H,10-15,17-18H2,1H3/t23-/m1/s1 FIODDBOCCRTBFK-HSZRJFAPSA-N 304707 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((tetrahydro-2H-pyran-4-yl)methyl)piperazine::US10144715, Compound 51-5 Oxysterols receptor LXR-beta 1017 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304707&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554652 381753411 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584340 CS(=O)(=O)c1cccc(c1)N1CCN(CC2CCOCC2)[C@H](C1)c1ccccc1 InChI=1S/C23H30N2O3S/c1-29(26,27)22-9-5-8-21(16-22)24-12-13-25(17-19-10-14-28-15-11-19)23(18-24)20-6-3-2-4-7-20/h2-9,16,19,23H,10-15,17-18H2,1H3/t23-/m1/s1 FIODDBOCCRTBFK-HSZRJFAPSA-N 304707 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((tetrahydro-2H-pyran-4-yl)methyl)piperazine::US10144715, Compound 51-5 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304707&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554652 381753411 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584342 CO[C@@H]1CC[C@H](CN2CCN(C[C@@H]2C(C)C)c2ccc(CO)c(c2)S(C)(=O)=O)CC1 InChI=1S/C23H38N2O4S/c1-17(2)22-15-24(20-8-7-19(16-26)23(13-20)30(4,27)28)11-12-25(22)14-18-5-9-21(29-3)10-6-18/h7-8,13,17-18,21-22,26H,5-6,9-12,14-16H2,1-4H3/t18-,21+,22-/m1/s1 KJMHYWFCANQSKY-BVYCBKJFSA-N 304708 (4-((S)-3-isopropyl-4-(((1r,4S)-4-methoxycyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 51-6 Oxysterols receptor LXR-beta 543 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304708&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883487 381753412 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584344 CO[C@@H]1CC[C@H](CN2CCN(C[C@@H]2C(C)C)c2ccc(CO)c(c2)S(C)(=O)=O)CC1 InChI=1S/C23H38N2O4S/c1-17(2)22-15-24(20-8-7-19(16-26)23(13-20)30(4,27)28)11-12-25(22)14-18-5-9-21(29-3)10-6-18/h7-8,13,17-18,21-22,26H,5-6,9-12,14-16H2,1-4H3/t18-,21+,22-/m1/s1 KJMHYWFCANQSKY-BVYCBKJFSA-N 304709 (4-((S)-3-isopropyl-4-(((1s,4R)-4-methoxycyclohexyl)methyl)piperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 51-7 Oxysterols receptor LXR-beta 51.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304709&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883487 381753413 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584346 CC(C)[C@H]1CN(CCN1CC1CCC(N(C)C1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H34F3N3O2S/c1-16(2)20-15-27(18-6-5-7-19(12-18)31(4,29)30)10-11-28(20)14-17-8-9-21(22(23,24)25)26(3)13-17/h5-7,12,16-17,20-21H,8-11,13-15H2,1-4H3/t17?,20-,21?/m1/s1 NTWOSTRWTSTGLC-TWMPVWRBSA-N 304710 (2S)-2-isopropyl-1-((1-methyl-6-(trifluoromethyl)piperidin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 52-1 Oxysterols receptor LXR-beta 19.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304710&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872090 381753414 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584348 CC1(C)CCC(O)(CN2CCN(C[C@@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)CC1 InChI=1S/C26H36N2O3S/c1-25(2)12-14-26(29,15-13-25)20-28-17-16-27(19-24(28)21-8-5-4-6-9-21)22-10-7-11-23(18-22)32(3,30)31/h4-11,18,24,29H,12-17,19-20H2,1-3H3/t24-/m1/s1 MVZUVIXDADTQPL-XMMPIXPASA-N 304711 (S)-4,4-dimethyl-1-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)cyclohexan-1-ol::US10144715, Compound 53-1 Oxysterols receptor LXR-beta 121 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304711&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883452 381753415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584350 CC1(C)CCC(O)(CN2CCN(C[C@H]2c2ccccc2)c2cccc(c2)S(C)(=O)=O)CC1 InChI=1S/C26H36N2O3S/c1-25(2)12-14-26(29,15-13-25)20-28-17-16-27(19-24(28)21-8-5-4-6-9-21)22-10-7-11-23(18-22)32(3,30)31/h4-11,18,24,29H,12-17,19-20H2,1-3H3/t24-/m0/s1 MVZUVIXDADTQPL-DEOSSOPVSA-N 304712 (R)-4,4-dimethyl-1-((4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)methyl)cyclohexan-1-ol::US10144715, Compound 53-2 Oxysterols receptor LXR-beta 609 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304712&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883454 381753416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583537 CC(C)[C@@H]1CN(CCN1C(=O)OCC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H32N2O4S/c1-15(2)18-13-21(16-8-7-9-17(12-16)27(6,24)25)10-11-22(18)19(23)26-14-20(3,4)5/h7-9,12,15,18H,10-11,13-14H2,1-6H3/t18-/m0/s1 BQOGKXMLVPOTDB-SFHVURJKSA-N 304323 US10144715, Compound 5-6::neopentyl (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 14.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304323&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554404 381753037 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583539 CCC(C)OC(=O)N1CCN(C[C@H]1C(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H30N2O4S/c1-6-15(4)25-19(22)21-11-10-20(13-18(21)14(2)3)16-8-7-9-17(12-16)26(5,23)24/h7-9,12,14-15,18H,6,10-11,13H2,1-5H3/t15?,18-/m0/s1 YQPPVZXVIKAMAP-PKHIMPSTSA-N 304324 US10144715, Compound 5-7::isobutyl (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304324&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554405 381753038 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583541 CC(C)OC(=O)N1CCN(CC1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H26N2O4S/c1-16(2)27-21(24)23-13-12-22(15-20(23)17-8-5-4-6-9-17)18-10-7-11-19(14-18)28(3,25)26/h4-11,14,16,20H,12-13,15H2,1-3H3 COJAIRVRRRQVCT-UHFFFAOYSA-N 304325 US10144715, Compound 5-8::isopropyl 4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta 732 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304325&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554406 381753039 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583543 CC(C)(C)OC(=O)N1CCN(C[C@H]1C(C)(C)O)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H30N2O5S/c1-18(2,3)26-17(22)21-11-10-20(13-16(21)19(4,5)23)14-8-7-9-15(12-14)27(6,24)25/h7-9,12,16,23H,10-11,13H2,1-6H3/t16-/m0/s1 CKOGJOSNUWGMKO-INIZCTEOSA-N 304326 US10144715, Compound 6-1::tert-butyl (S)-2-(2-hydroxypropan-2-yl)-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 2648 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304326&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883425 381753040 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583545 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(10-13)30(3,28)29)8-9-27(15)18-24-7-6-17(25-18)19(21,22)23/h4-7,10,12,15H,8-9,11H2,1-3H3/t15-/m0/s1 YTEDTWJJQBCOTI-HNNXBMFYSA-N 50177012 CHEMBL3814153::US10144715, Compound 7-32 Oxysterols receptor LXR-beta 1.000 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883427 346549208 CHEMBL3814153 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583547 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(10-13)30(3,28)29)8-9-27(15)18-24-7-6-17(25-18)19(21,22)23/h4-7,10,12,15H,8-9,11H2,1-3H3/t15-/m0/s1 YTEDTWJJQBCOTI-HNNXBMFYSA-N 50177012 CHEMBL3814153::US10144715, Compound 7-32 Oxysterols receptor LXR-beta 6.00 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883427 346549208 CHEMBL3814153 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583549 CC(C)[C@@H]1CN(CCN1c1ncccn1)c1cccc(c1)S(C)(=O)=O InChI=1S/C18H24N4O2S/c1-14(2)17-13-21(10-11-22(17)18-19-8-5-9-20-18)15-6-4-7-16(12-15)25(3,23)24/h4-9,12,14,17H,10-11,13H2,1-3H3/t17-/m0/s1 SIHBKJYMUGXIQO-KRWDZBQOSA-N 304328 (R)-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine::US10144715, Compound 7-2 Oxysterols receptor LXR-beta 123 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304328&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554407 381753042 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583551 CC(C)[C@@H]1CN(CCN1c1nc(C)cc(C)n1)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H28N4O2S/c1-14(2)19-13-23(17-7-6-8-18(12-17)27(5,25)26)9-10-24(19)20-21-15(3)11-16(4)22-20/h6-8,11-12,14,19H,9-10,13H2,1-5H3/t19-/m0/s1 XCJHHCQJSSGDOW-IBGZPJMESA-N 304329 (R)-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-4,6-dimethylpyrimidine::US10144715, Compound 7-3 Oxysterols receptor LXR-beta 48.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304329&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554408 381753043 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583553 CC(C)[C@@H]1CN(CCN1c1ncc(Cl)cn1)c1cccc(c1)S(C)(=O)=O InChI=1S/C18H23ClN4O2S/c1-13(2)17-12-22(15-5-4-6-16(9-15)26(3,24)25)7-8-23(17)18-20-10-14(19)11-21-18/h4-6,9-11,13,17H,7-8,12H2,1-3H3/t17-/m0/s1 UACFMLHTYGOORV-KRWDZBQOSA-N 304330 (R)-5-chloro-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine::US10144715, Compound 7-4 Oxysterols receptor LXR-beta 17.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304330&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554409 381753044 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583555 CC(C)[C@@H]1CN(CCN1c1ncc(cn1)C1CC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H28N4O2S/c1-15(2)20-14-24(18-5-4-6-19(11-18)28(3,26)27)9-10-25(20)21-22-12-17(13-23-21)16-7-8-16/h4-6,11-13,15-16,20H,7-10,14H2,1-3H3/t20-/m0/s1 GKSVBRSAJNOJOL-FQEVSTJZSA-N 304331 (R)-5-cyclopropyl-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine::US10144715, Compound 7-5 Oxysterols receptor LXR-beta 26.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304331&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554410 381753045 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583558 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H30N4O2S/c1-15(2)19-9-10-22-21(23-19)25-12-11-24(14-20(25)16(3)4)17-7-6-8-18(13-17)28(5,26)27/h6-10,13,15-16,20H,11-12,14H2,1-5H3/t20-/m0/s1 GPHDHOZJIQGWQC-FQEVSTJZSA-N 304332 (R)-5-isopropyl-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine::US10144715, Compound 7-6 Oxysterols receptor LXR-beta 53.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304332&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554411 381753046 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583560 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C#N)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22FN5O2S/c1-13(2)17-12-24(15-4-5-16(20)18(10-15)28(3,26)27)8-9-25(17)19-22-7-6-14(11-21)23-19/h4-7,10,13,17H,8-9,12H2,1-3H3/t17-/m0/s1 ZIQOKIRETRSSNJ-KRWDZBQOSA-N 304333 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyrimidine-4-carbonitrile::US10144715, Compound 7-7 Oxysterols receptor LXR-beta 47.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554412 381753047 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583562 CC(C)[C@@H]1CN(CCN1c1nc(C)cc(n1)C#N)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24FN5O2S/c1-13(2)18-12-25(16-5-6-17(21)19(10-16)29(4,27)28)7-8-26(18)20-23-14(3)9-15(11-22)24-20/h5-6,9-10,13,18H,7-8,12H2,1-4H3/t18-/m0/s1 ZUXREYZZGMXZDO-SFHVURJKSA-N 304334 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-6-methylpyrimidine-4-carbonitrile::US10144715, Compound 7-8 Oxysterols receptor LXR-beta 1012 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304334&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554413 381753048 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583564 COC(=O)c1cnc(nc1)N1CCN(C[C@H]1C(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H26N4O4S/c1-14(2)18-13-23(16-6-5-7-17(10-16)29(4,26)27)8-9-24(18)20-21-11-15(12-22-20)19(25)28-3/h5-7,10-12,14,18H,8-9,13H2,1-4H3/t18-/m0/s1 YOJHXYWLQQGBDQ-SFHVURJKSA-N 304335 US10144715, Compound 7-9::methyl (R)-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 56.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304335&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554414 381753049 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583566 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C1CC1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H27FN4O2S/c1-14(2)19-13-25(16-6-7-17(22)20(12-16)29(3,27)28)10-11-26(19)21-23-9-8-18(24-21)15-4-5-15/h6-9,12,14-15,19H,4-5,10-11,13H2,1-3H3/t19-/m0/s1 AHSVAMKJVNIBDA-IBGZPJMESA-N 304336 (R)-4-cyclopropyl-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyrimidine::US10144715, Compound 7-10 Oxysterols receptor LXR-beta 13.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304336&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883509 381753050 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583569 CC(C)[C@@H]1CN(CCN1c1ncc(OC(F)F)cn1)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H24F2N4O3S/c1-13(2)17-12-24(14-5-4-6-16(9-14)29(3,26)27)7-8-25(17)19-22-10-15(11-23-19)28-18(20)21/h4-6,9-11,13,17-18H,7-8,12H2,1-3H3/t17-/m0/s1 ALICKBCBWBIBQP-KRWDZBQOSA-N 304337 (R)-5-(difluoromethoxy)-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine::US10144715, Compound 7-11 Oxysterols receptor LXR-beta 78.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304337&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554415 381753051 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583571 CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H24ClFN4O2S/c1-12(2)17-11-24(14-5-6-16(21)18(9-14)28(4,26)27)7-8-25(17)19-22-10-15(20)13(3)23-19/h5-6,9-10,12,17H,7-8,11H2,1-4H3/t17-/m0/s1 JSVXZVWRZPKCFT-KRWDZBQOSA-N 304338 (R)-5-chloro-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methylpyrimidine::US10144715, Compound 7-12 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304338&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554416 381753052 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583574 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O2S/c1-13(2)16-12-25(14-5-4-6-15(11-14)29(3,27)28)9-10-26(16)18-23-8-7-17(24-18)19(20,21)22/h4-8,11,13,16H,9-10,12H2,1-3H3/t16-/m0/s1 XVRHEEOCNTZUNF-INIZCTEOSA-N 50177011 CHEMBL3815014::US10144715, Compound 7-13 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049313 346549207 CHEMBL3815014 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583576 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O2S/c1-13(2)16-12-25(14-5-4-6-15(11-14)29(3,27)28)9-10-26(16)18-23-8-7-17(24-18)19(20,21)22/h4-8,11,13,16H,9-10,12H2,1-3H3/t16-/m0/s1 XVRHEEOCNTZUNF-INIZCTEOSA-N 50177011 CHEMBL3815014::US10144715, Compound 7-13 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 127049313 346549207 CHEMBL3815014 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583578 COC(=O)c1cnc(nc1)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H25FN4O4S/c1-13(2)17-12-24(15-5-6-16(21)18(9-15)30(4,27)28)7-8-25(17)20-22-10-14(11-23-20)19(26)29-3/h5-6,9-11,13,17H,7-8,12H2,1-4H3/t17-/m0/s1 GGEACMROXJSGGX-KRWDZBQOSA-N 304340 US10144715, Compound 7-14::methyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 285 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304340&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554417 381753054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583580 COC(=O)c1ccnc(n1)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H25FN4O4S/c1-13(2)17-12-24(14-5-6-15(21)18(11-14)30(4,27)28)9-10-25(17)20-22-8-7-16(23-20)19(26)29-3/h5-8,11,13,17H,9-10,12H2,1-4H3/t17-/m0/s1 ZMSACEOQWGFPTA-KRWDZBQOSA-N 304341 US10144715, Compound 7-15::methyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)pyrimidine-4-carboxylate Oxysterols receptor LXR-beta 20.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304341&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554418 381753055 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583581 CC(C)[C@@H]1CN(CCN1c1ncc(Br)cn1)c1cccc(c1)S(C)(=O)=O InChI=1S/C18H23BrN4O2S/c1-13(2)17-12-22(15-5-4-6-16(9-15)26(3,24)25)7-8-23(17)18-20-10-14(19)11-21-18/h4-6,9-11,13,17H,7-8,12H2,1-3H3/t17-/m0/s1 LVJRBXXPKZYGIG-KRWDZBQOSA-N 304342 (R)-5-bromo-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyrimidine::US10144715, Compound 7-16 Oxysterols receptor LXR-beta 16.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304342&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554419 381753056 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583583 CC(C)[C@@H]1CN(CCN1c1nc(C)cc(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H24F4N4O2S/c1-12(2)16-11-27(14-5-6-15(21)17(10-14)31(4,29)30)7-8-28(16)19-25-13(3)9-18(26-19)20(22,23)24/h5-6,9-10,12,16H,7-8,11H2,1-4H3/t16-/m0/s1 GIPBQDFCFPOLCY-INIZCTEOSA-N 304343 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methyl-6-(trifluoromethyl)pyrimidine::US10144715, Compound 7-18 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304343&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 130308186 381753057 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583585 CCOC(=O)c1cnc(nc1C)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H29FN4O4S/c1-6-31-21(28)17-12-24-22(25-15(17)4)27-10-9-26(13-19(27)14(2)3)16-7-8-18(23)20(11-16)32(5,29)30/h7-8,11-12,14,19H,6,9-10,13H2,1-5H3/t19-/m0/s1 AEMSEMKBOULOJG-IBGZPJMESA-N 304344 US10144715, Compound 7-19::ethyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methylpyrimidine-5-carboxylate Oxysterols receptor LXR-beta 17.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304344&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554420 381753058 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584352 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(CNC(C)=O)c(c1)S(C)(=O)=O InChI=1S/C22H28F3N5O3S/c1-14(2)18-13-29(9-10-30(18)21-26-8-7-20(28-21)22(23,24)25)17-6-5-16(12-27-15(3)31)19(11-17)34(4,32)33/h5-8,11,14,18H,9-10,12-13H2,1-4H3,(H,27,31)/t18-/m0/s1 IBJHNZQOUGJVCC-SFHVURJKSA-N 304713 (R)-N-(4-(3-isopropyl-4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)benzyl)acetamide::US10144715, Compound 54-1 Oxysterols receptor LXR-beta 51.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304713&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883577 381753417 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584354 CC(C)[C@@H]1CN(CCN1c1ncc(CNC(C)=O)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H27F4N5O3S/c1-13(2)18-12-30(16-5-6-17(23)19(9-16)35(4,33)34)7-8-31(18)21-28-11-15(10-27-14(3)32)20(29-21)22(24,25)26/h5-6,9,11,13,18H,7-8,10,12H2,1-4H3,(H,27,32)/t18-/m0/s1 CSTOAOCVMBEIPA-SFHVURJKSA-N 304714 US10144715, Compound 54-2b Oxysterols receptor LXR-beta 81.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304714&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883457 381753418 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584355 CCC(C)[C@H]1CN(CCN1C(=O)OC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H32N2O4S/c1-7-15(2)18-14-21(11-12-22(18)19(23)26-20(3,4)5)16-9-8-10-17(13-16)27(6,24)25/h8-10,13,15,18H,7,11-12,14H2,1-6H3/t15?,18-/m1/s1 AKYJJHPDFWVLIM-KPMSDPLLSA-N 304289 US10144715, Compound 1-2::tert-butyl (S)-2-isobutyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 199 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304289&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554377 381753004 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584357 CC(C)(C)OC(=O)N1CCN(CC1c1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H28N2O4S/c1-22(2,3)28-21(25)24-14-13-23(16-20(24)17-9-6-5-7-10-17)18-11-8-12-19(15-18)29(4,26)27/h5-12,15,20H,13-14,16H2,1-4H3 QOZZSQFYXBVSQA-UHFFFAOYSA-N 304292 US10144715, Compound 1-5::tert-butyl 4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine-1-carboxylate Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304292&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554380 381753007 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584359 CC(C)(C)OC(=O)N1CCN(C[C@@H]1Cc1ccccc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H30N2O4S/c1-23(2,3)29-22(26)25-14-13-24(17-20(25)15-18-9-6-5-7-10-18)19-11-8-12-21(16-19)30(4,27)28/h5-12,16,20H,13-15,17H2,1-4H3/t20-/m0/s1 WXTIZJALIIAVIJ-FQEVSTJZSA-N 304294 US10144715, Compound 1-7::tert-butyl (S)-2-benzyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta 7325 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304294&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554382 381753009 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584361 CC(C)(C)OC(=O)N1CCN(CC1c1ccc(Br)cc1)c1cccc(c1)S(C)(=O)=O InChI=1S/C22H27BrN2O4S/c1-22(2,3)29-21(26)25-13-12-24(15-20(25)16-8-10-17(23)11-9-16)18-6-5-7-19(14-18)30(4,27)28/h5-11,14,20H,12-13,15H2,1-4H3 BWDVFZSNKBBPGB-UHFFFAOYSA-N 304299 US10144715, Compound 1-12::tert-butyl 2-(4-bromophenyl)-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554387 381753014 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584362 CC(C)[C@@H]1CN(CCN1C(=O)OC(C)(C)C)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H30N2O4S/c1-14(2)17-13-20(10-11-21(17)18(22)25-19(3,4)5)15-8-7-9-16(12-15)26(6,23)24/h7-9,12,14,17H,10-11,13H2,1-6H3/t17-/m0/s1 HDOWNKAPIXMAAE-KRWDZBQOSA-N 304288 US10144715, Compound 1-1::US10144715, Compound 2-2::tert-butyl (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine-1-carboxylate Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883536 381753003 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584364 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H24ClF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3 SYWHAWSOSMSFBS-UHFFFAOYSA-N 304537 1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-1 Oxysterols receptor LXR-beta 27500 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304537&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872132 381753246 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584366 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C25H24ClF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m0/s1 SYWHAWSOSMSFBS-DEOSSOPVSA-N 304538 (R)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-2 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304538&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872080 381753247 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584368 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(c(Cl)c2)C(F)(F)F)[C@H](C1)c1ccccc1 InChI=1S/C25H24ClF3N2O2S/c1-34(32,33)21-9-5-8-20(15-21)30-12-13-31(24(17-30)19-6-3-2-4-7-19)16-18-10-11-22(23(26)14-18)25(27,28)29/h2-11,14-15,24H,12-13,16-17H2,1H3/t24-/m1/s1 SYWHAWSOSMSFBS-XMMPIXPASA-N 304539 (S)-1-(3-chloro-4-(trifluoromethyl)benzyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-3 Oxysterols receptor LXR-beta 30000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304539&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872094 381753248 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584370 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(cc2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C25H25F3N2O2S/c1-33(31,32)23-9-5-8-22(16-23)29-14-15-30(24(18-29)20-6-3-2-4-7-20)17-19-10-12-21(13-11-19)25(26,27)28/h2-13,16,24H,14-15,17-18H2,1H3/t24-/m0/s1 JWDYOAJOJBVJKK-DEOSSOPVSA-N 304550 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(4-(trifluoromethyl)benzyl)piperazine::US10144715, Compound 46-14 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304550&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554549 381753259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584372 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)[C@@H](C1)c1ccccc1 InChI=1S/C24H24F3N3O2S/c1-33(31,32)21-9-5-8-20(14-21)29-12-13-30(22(17-29)19-6-3-2-4-7-19)16-18-10-11-23(28-15-18)24(25,26)27/h2-11,14-15,22H,12-13,16-17H2,1H3/t22-/m0/s1 CTCGRQVHZGKQJF-QFIPXVFZSA-N 304578 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-44 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304578&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554572 381753283 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584374 Cc1nc(ccc1CN1CCN(CC1c1ccccc1)c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C25H26F3N3O2S/c1-18-20(11-12-24(29-18)25(26,27)28)16-31-14-13-30(17-23(31)19-7-4-3-5-8-19)21-9-6-10-22(15-21)34(2,32)33/h3-12,15,23H,13-14,16-17H2,1-2H3 JMADGMMPWWZEJG-UHFFFAOYSA-N 304581 1-((2-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-47 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304581&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554575 381753286 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584376 Cc1cc(CN2CCN(CC2c2ccccc2)c2cccc(c2)S(C)(=O)=O)cnc1C(F)(F)F InChI=1S/C25H26F3N3O2S/c1-18-13-19(15-29-24(18)25(26,27)28)16-31-12-11-30(17-23(31)20-7-4-3-5-8-20)21-9-6-10-22(14-21)34(2,32)33/h3-10,13-15,23H,11-12,16-17H2,1-2H3 DZRXBHCLWHDURN-UHFFFAOYSA-N 304582 1-((5-methyl-6-(trifluoromethyl)pyridin-3-yl)methyl)-4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazine::US10144715, Compound 46-48 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304582&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554576 381753287 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584378 CS(=O)(=O)c1ccc(F)c(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C24H23F4N3O2S/c1-34(32,33)19-8-9-20(25)21(13-19)31-12-11-30(22(16-31)18-5-3-2-4-6-18)15-17-7-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3 WKCWHGGHDMRGIU-UHFFFAOYSA-N 304584 4-(2-fluoro-5-(methylsulfonyl)phenyl)-2-phenyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-50 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304584&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554578 381753289 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584380 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccc(Cl)cc1 InChI=1S/C24H23ClF3N3O2S/c1-34(32,33)21-4-2-3-20(13-21)30-11-12-31(22(16-30)18-6-8-19(25)9-7-18)15-17-5-10-23(29-14-17)24(26,27)28/h2-10,13-14,22H,11-12,15-16H2,1H3 UKSLFOSELGAJFH-UHFFFAOYSA-N 304588 2-(4-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-54 Oxysterols receptor LXR-beta 10532 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304588&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554582 381753293 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584382 CS(=O)(=O)c1cccc(c1)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1cccc(Cl)c1 InChI=1S/C24H23ClF3N3O2S/c1-34(32,33)21-7-3-6-20(13-21)30-10-11-31(22(16-30)18-4-2-5-19(25)12-18)15-17-8-9-23(29-14-17)24(26,27)28/h2-9,12-14,22H,10-11,15-16H2,1H3 ANUJRQJBYNNLFL-UHFFFAOYSA-N 304589 2-(3-chlorophenyl)-4-(3-(methylsulfonyl)phenyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-55 Oxysterols receptor LXR-beta 11009 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304589&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554583 381753294 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584384 COC(=O)c1ccc(cc1S(C)(=O)=O)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C26H26F3N3O4S/c1-36-25(33)21-10-9-20(14-23(21)37(2,34)35)31-12-13-32(22(17-31)19-6-4-3-5-7-19)16-18-8-11-24(30-15-18)26(27,28)29/h3-11,14-15,22H,12-13,16-17H2,1-2H3 OZCHBKWUMMUQCS-UHFFFAOYSA-N 304593 US10144715, Compound 46-59::methyl 2-(methylsulfonyl)-4-(3-phenyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)benzoate Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304593&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872071 381753298 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584386 Cc1cccc(c1)C1CN(CCN1Cc1ccc(nc1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C25H26F3N3O2S/c1-18-5-3-6-20(13-18)23-17-30(21-7-4-8-22(14-21)34(2,32)33)11-12-31(23)16-19-9-10-24(29-15-19)25(26,27)28/h3-10,13-15,23H,11-12,16-17H2,1-2H3 HCVLWMWRAMRONF-UHFFFAOYSA-N 304596 4-(3-(methylsulfonyl)phenyl)-2-(m-tolyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazine::US10144715, Compound 46-62 Oxysterols receptor LXR-beta 6760 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304596&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554589 381753301 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 584388 CS(=O)(=O)c1cc(ccc1CO)N1CCN(Cc2ccc(nc2)C(F)(F)F)C(C1)c1ccccc1 InChI=1S/C25H26F3N3O3S/c1-35(33,34)23-13-21(9-8-20(23)17-32)30-11-12-31(22(16-30)19-5-3-2-4-6-19)15-18-7-10-24(29-14-18)25(26,27)28/h2-10,13-14,22,32H,11-12,15-17H2,1H3 IPVMIWRZULJDJV-UHFFFAOYSA-N 304601 (2-(methylsulfonyl)-4-(3-phenyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)phenyl)methanol::US10144715, Compound 47-1 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304601&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872067 381753306 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583587 CC(C)[C@@H]1CN(CCN1c1ncc(Br)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H24BrFN4O2S/c1-12(2)17-11-24(14-5-6-16(21)18(9-14)28(4,26)27)7-8-25(17)19-22-10-15(20)13(3)23-19/h5-6,9-10,12,17H,7-8,11H2,1-4H3/t17-/m0/s1 RKMWUDYBRYAWCA-KRWDZBQOSA-N 304345 (R)-5-bromo-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-methylpyrimidine::US10144715, Compound 7-20 Oxysterols receptor LXR-beta 8.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304345&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 130305012 381753059 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583588 CC(C)[C@@H]1CN(CCN1c1ncc(C#N)c(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H21F4N5O2S/c1-12(2)16-11-28(14-4-5-15(21)17(8-14)32(3,30)31)6-7-29(16)19-26-10-13(9-25)18(27-19)20(22,23)24/h4-5,8,10,12,16H,6-7,11H2,1-3H3/t16-/m0/s1 YOHQZBSJLACBMS-INIZCTEOSA-N 304346 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carbonitrile::US10144715, Compound 7-21 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304346&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554421 381753060 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583589 CCOC(=O)c1cnc(nc1C)N1CCN(CC1CC(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H24F4N4O4S/c1-4-33-19(30)16-11-26-20(27-13(16)2)29-8-7-28(12-15(29)10-21(23,24)25)14-5-6-17(22)18(9-14)34(3,31)32/h5-6,9,11,15H,4,7-8,10,12H2,1-3H3 FIENRIHDSBDFBG-UHFFFAOYSA-N 304347 US10144715, Compound 7-22::ethyl 2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(2,2,2-trifluoroethyl)piperazin-1-yl)-4-methylpyrimidine-5-carboxylate Oxysterols receptor LXR-beta 17.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304347&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554422 381753061 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583592 CC(C)(O)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O3S/c1-18(2,27)16-12-25(13-5-4-6-14(11-13)30(3,28)29)9-10-26(16)17-23-8-7-15(24-17)19(20,21)22/h4-8,11,16,27H,9-10,12H2,1-3H3/t16-/m0/s1 DTDSYQPSZOADNN-INIZCTEOSA-N 304349 (S)-2-(4-(3-(methylsulfonyl)phenyl)-1-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-2-yl)propan-2-ol::US10144715, Compound 7-24 Oxysterols receptor LXR-beta 43.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304349&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554424 381753063 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583594 CC(C)(O)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O3S/c1-18(2,27)16-12-25(13-5-4-6-14(11-13)30(3,28)29)9-10-26(16)17-23-8-7-15(24-17)19(20,21)22/h4-8,11,16,27H,9-10,12H2,1-3H3/t16-/m0/s1 DTDSYQPSZOADNN-INIZCTEOSA-N 304349 (S)-2-(4-(3-(methylsulfonyl)phenyl)-1-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-2-yl)propan-2-ol::US10144715, Compound 7-24 Oxysterols receptor LXR-beta 14.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304349&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554424 381753063 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583596 CC([C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C19H20F6N4O2S/c1-12(18(20,21)22)15-11-28(13-4-3-5-14(10-13)32(2,30)31)8-9-29(15)17-26-7-6-16(27-17)19(23,24)25/h3-7,10,12,15H,8-9,11H2,1-2H3/t12?,15-/m0/s1 ISXPNMSKZHGGLC-CVRLYYSRSA-N 304350 (R)-2-(2-(1,1-difluoroethyl)-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 7-25 Oxysterols receptor LXR-beta 504 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304350&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554425 381753064 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583598 CC([C@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C19H20F6N4O2S/c1-12(18(20,21)22)15-11-28(13-4-3-5-14(10-13)32(2,30)31)8-9-29(15)17-26-7-6-16(27-17)19(23,24)25/h3-7,10,12,15H,8-9,11H2,1-2H3/t12?,15-/m1/s1 ISXPNMSKZHGGLC-WPZCJLIBSA-N 304351 (S)-2-(2-(1,1-difluoroethyl)-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 7-26 Oxysterols receptor LXR-beta 29.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304351&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554426 381753065 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583600 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)C(F)(F)F)c1nccc(n1)C(F)(F)F InChI=1S/C17H16F6N4O2S/c1-30(28,29)12-4-2-3-11(9-12)26-7-8-27(14(10-26)17(21,22)23)15-24-6-5-13(25-15)16(18,19)20/h2-6,9,14H,7-8,10H2,1H3/t14-/m0/s1 FWLREOYIIBBODP-AWEZNQCLSA-N 304352 (R)-2-(4-(3-(methylsulfonyl)phenyl)-2-(trifluoromethyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 7-27 Oxysterols receptor LXR-beta 522 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304352&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554427 381753066 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583602 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)C(F)(F)F)c1nccc(n1)C(F)(F)F InChI=1S/C17H16F6N4O2S/c1-30(28,29)12-4-2-3-11(9-12)26-7-8-27(14(10-26)17(21,22)23)15-24-6-5-13(25-15)16(18,19)20/h2-6,9,14H,7-8,10H2,1H3/t14-/m1/s1 FWLREOYIIBBODP-CQSZACIVSA-N 304353 (S)-2-(4-(3-(methylsulfonyl)phenyl)-2-(trifluoromethyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 7-28 Oxysterols receptor LXR-beta 40.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304353&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554428 381753067 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583605 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H21F3N4O2S/c1-32(30,31)18-9-5-8-17(14-18)28-12-13-29(19(15-28)16-6-3-2-4-7-16)21-26-11-10-20(27-21)22(23,24)25/h2-11,14,19H,12-13,15H2,1H3/t19-/m1/s1 GWLPLKIBBKZUGZ-LJQANCHMSA-N 304355 (S)-2-(4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine::BDBM304356::US10144715, Compound 7-30 Oxysterols receptor LXR-beta >50000 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304355&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554430 381753069 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583607 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H21F3N4O2S/c1-32(30,31)18-9-5-8-17(14-18)28-12-13-29(19(15-28)16-6-3-2-4-7-16)21-26-11-10-20(27-21)22(23,24)25/h2-11,14,19H,12-13,15H2,1H3/t19-/m1/s1 GWLPLKIBBKZUGZ-LJQANCHMSA-N 304355 (S)-2-(4-(3-(methylsulfonyl)phenyl)-2-phenylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine::BDBM304356::US10144715, Compound 7-30 Oxysterols receptor LXR-beta 94.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304355&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554430 381753069 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583609 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(10-13)30(3,28)29)8-9-27(15)18-24-7-6-17(25-18)19(21,22)23/h4-7,10,12,15H,8-9,11H2,1-3H3/t15-/m0/s1 YTEDTWJJQBCOTI-HNNXBMFYSA-N 50177012 CHEMBL3814153::US10144715, Compound 7-32 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883427 346549208 CHEMBL3814153 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583611 CC(C)[C@@H]1CN(CCN1c1cc(ccn1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H24F3N3O2S/c1-14(2)18-13-25(16-5-4-6-17(12-16)29(3,27)28)9-10-26(18)19-11-15(7-8-24-19)20(21,22)23/h4-8,11-12,14,18H,9-10,13H2,1-3H3/t18-/m0/s1 UXSANGGIDQWNBS-SFHVURJKSA-N 304358 (R)-1-(5-(difluoromethyl)pyridin-2-yl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 7-34 Oxysterols receptor LXR-beta 284 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304358&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554431 381753072 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583613 CC(C)[C@@H]1CN(CCN1c1ccc(cn1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H24F3N3O2S/c1-14(2)18-13-25(16-5-4-6-17(11-16)29(3,27)28)9-10-26(18)19-8-7-15(12-24-19)20(21,22)23/h4-8,11-12,14,18H,9-10,13H2,1-3H3/t18-/m0/s1 LOLXQIJKVFWHMU-SFHVURJKSA-N 304359 (R)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)-1-(5-(trifluoromethyl)pyridin-2-yl)piperazine::US10144715, Compound 7-35 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304359&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883555 381753073 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583615 CC(C)[C@@H]1CN(CCN1c1ccc(cn1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23F4N3O2S/c1-13(2)17-12-26(15-5-6-16(21)18(10-15)30(3,28)29)8-9-27(17)19-7-4-14(11-25-19)20(22,23)24/h4-7,10-11,13,17H,8-9,12H2,1-3H3/t17-/m0/s1 CDVXSTXXLZGAKK-KRWDZBQOSA-N 304360 (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropyl-1-(5-(trifluoromethyl)pyridin-2-yl)piperazine::US10144715, Compound 18-1::US10144715, Compound 7-36 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304360&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554432 381753074 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583618 CC(C)[C@@H]1CN(CCN1c1ccc(cn1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C21H23F3N4O2S/c1-14(2)18-13-27(17-6-4-15(11-25)19(10-17)31(3,29)30)8-9-28(18)20-7-5-16(12-26-20)21(22,23)24/h4-7,10,12,14,18H,8-9,13H2,1-3H3/t18-/m0/s1 GTBANCVUJSJFCU-SFHVURJKSA-N 304361 (R)-4-(3-isopropyl-4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 7-37 Oxysterols receptor LXR-beta 16.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304361&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554433 381753075 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583620 CC(C)[C@@H]1CN(CCN1c1cccc(n1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C21H23F3N4O2S/c1-14(2)17-13-27(16-8-7-15(12-25)18(11-16)31(3,29)30)9-10-28(17)20-6-4-5-19(26-20)21(22,23)24/h4-8,11,14,17H,9-10,13H2,1-3H3/t17-/m0/s1 HFCCGSATAPHJQZ-KRWDZBQOSA-N 304362 (R)-4-(3-isopropyl-4-(6-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 7-38 Oxysterols receptor LXR-beta 43.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304362&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554434 381753076 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583622 CC(C)[C@@H]1CN(CCN1c1cc(ccn1)C(F)(F)F)c1ccc(C#N)c(c1)S(C)(=O)=O InChI=1S/C21H23F3N4O2S/c1-14(2)18-13-27(17-5-4-15(12-25)19(11-17)31(3,29)30)8-9-28(18)20-10-16(6-7-26-20)21(22,23)24/h4-7,10-11,14,18H,8-9,13H2,1-3H3/t18-/m0/s1 LMSJILASXGEZTI-SFHVURJKSA-N 304363 (R)-4-(3-isopropyl-4-(4-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2-(methylsulfonyl)benzonitrile::US10144715, Compound 7-39 Oxysterols receptor LXR-beta 25.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304363&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554435 381753077 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583624 CS(=O)(=O)c1cccc(c1)N1CCN([C@H](C1)c1ccccc1)c1ccc(cn1)C(F)(F)F InChI=1S/C23H22F3N3O2S/c1-32(30,31)20-9-5-8-19(14-20)28-12-13-29(21(16-28)17-6-3-2-4-7-17)22-11-10-18(15-27-22)23(24,25)26/h2-11,14-15,21H,12-13,16H2,1H3/t21-/m1/s1 BPSAPWHNUPNODL-OAQYLSRUSA-N 304364 (S)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-(5-(trifluoromethyl)pyridin-2-yl)piperazine::US10144715, Compound 7-40 Oxysterols receptor LXR-beta 4357 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304364&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554436 381753078 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583626 CC(C)[C@@H]1CN(CCN1c1nc(ccc1Cl)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C20H23ClF3N3O2S/c1-13(2)17-12-26(14-5-4-6-15(11-14)30(3,28)29)9-10-27(17)19-16(21)7-8-18(25-19)20(22,23)24/h4-8,11,13,17H,9-10,12H2,1-3H3/t17-/m0/s1 NLQZHFCXLSURKR-KRWDZBQOSA-N 304365 (R)-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazine::US10144715, Compound 7-41 Oxysterols receptor LXR-beta 8.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304365&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554437 381753079 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583628 CC(C)[C@@H]1CN(CCN1c1ncc(cc1[N+]([O-])=O)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H22F4N4O4S/c1-12(2)17-11-26(14-4-5-15(21)18(9-14)33(3,31)32)6-7-27(17)19-16(28(29)30)8-13(10-25-19)20(22,23)24/h4-5,8-10,12,17H,6-7,11H2,1-3H3/t17-/m0/s1 YRDLIUCBIUYNLE-KRWDZBQOSA-N 304366 (R)-4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropyl-1-(3-nitro-5-(trifluoromethyl)pyridin-2-yl)piperazine::US10144715, Compound 7-42 Oxysterols receptor LXR-beta 67.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304366&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118872028 381753080 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583630 CCOC(=O)c1ccc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H27F4N3O4S/c1-5-34-22(31)16-7-9-20(28-21(16)23(25,26)27)30-11-10-29(13-18(30)14(2)3)15-6-8-17(24)19(12-15)35(4,32)33/h6-9,12,14,18H,5,10-11,13H2,1-4H3/t18-/m0/s1 AJMKGXLALRFWCE-SFHVURJKSA-N 304367 US10144715, Compound 7-43::methyl (R)-6-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-2-(trifluoromethyl)nicotinate Oxysterols receptor LXR-beta 17.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304367&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554438 381753081 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583632 CC(C)[C@@H]1CN(CCN1c1cnc(cn1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(8-13)30(3,28)29)6-7-27(15)18-10-24-17(9-25-18)19(21,22)23/h4-5,8-10,12,15H,6-7,11H2,1-3H3/t15-/m0/s1 CENYEUAKMJYAFN-HNNXBMFYSA-N 304368 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyrazine::US10144715, Compound 7-44::US10144715, Compound 7-49 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304368&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883547 381753082 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583634 CC(C)[C@@H]1CN(CCN1c1cncc(n1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(8-13)30(3,28)29)6-7-27(15)18-10-24-9-17(25-18)19(21,22)23/h4-5,8-10,12,15H,6-7,11H2,1-3H3/t15-/m0/s1 AIQBGPRFVDOSKB-HNNXBMFYSA-N 304369 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-6-(trifluoromethyl)pyrazine::US10144715, Compound 7-45 Oxysterols receptor LXR-beta 12.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304369&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554439 381753083 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583636 CC(C)[C@@H]1CN(CCN1c1cnc(C)cn1)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H26N4O2S/c1-14(2)18-13-22(16-6-5-7-17(10-16)26(4,24)25)8-9-23(18)19-12-20-15(3)11-21-19/h5-7,10-12,14,18H,8-9,13H2,1-4H3/t18-/m0/s1 PMGLBELYGFHRLD-SFHVURJKSA-N 304370 (R)-3-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-6-methylpyridazine::US10144715, Compound 7-46 Oxysterols receptor LXR-beta 2146 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304370&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554440 381753084 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583638 CC(C)[C@@H]1CN(CCN1c1cnc(cn1)C1CC1)c1cccc(c1)S(C)(=O)=O InChI=1S/C21H28N4O2S/c1-15(2)20-14-24(17-5-4-6-18(11-17)28(3,26)27)9-10-25(20)21-13-22-19(12-23-21)16-7-8-16/h4-6,11-13,15-16,20H,7-10,14H2,1-3H3/t20-/m0/s1 MRQOHXAVBWIJHS-FQEVSTJZSA-N 304371 (R)-3-cyclopropyl-6-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)pyridazine::US10144715, Compound 7-47 Oxysterols receptor LXR-beta 478 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304371&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554441 381753085 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583640 CC(C)[C@@H]1CN(CCN1c1cnc(cn1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O2S/c1-13(2)16-12-25(14-5-4-6-15(9-14)29(3,27)28)7-8-26(16)18-11-23-17(10-24-18)19(20,21)22/h4-6,9-11,13,16H,7-8,12H2,1-3H3/t16-/m0/s1 HBRYTPUBFUUNKX-INIZCTEOSA-N 304372 (R)-3-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-6-(trifluoromethyl)pyridazine::US10144715, Compound 7-48 Oxysterols receptor LXR-beta 116 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304372&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554442 381753086 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583642 CC(C)[C@@H]1CN(CCN1c1cnc(cn1)C(F)(F)F)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C19H22F4N4O2S/c1-12(2)15-11-26(13-4-5-14(20)16(8-13)30(3,28)29)6-7-27(15)18-10-24-17(9-25-18)19(21,22)23/h4-5,8-10,12,15H,6-7,11H2,1-3H3/t15-/m0/s1 CENYEUAKMJYAFN-HNNXBMFYSA-N 304368 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-5-(trifluoromethyl)pyrazine::US10144715, Compound 7-44::US10144715, Compound 7-49 Oxysterols receptor LXR-beta 82.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304368&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883547 381753082 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583644 CC(C)[C@@H]1CN(CCN1c1ccnc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C19H23F3N4O2S/c1-13(2)16-12-25(14-5-4-6-15(11-14)29(3,27)28)9-10-26(16)17-7-8-23-18(24-17)19(20,21)22/h4-8,11,13,16H,9-10,12H2,1-3H3/t16-/m0/s1 XSTBCTRLFMQARX-INIZCTEOSA-N 304374 (R)-4-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-2-(trifluoromethyl)pyrimidine::US10144715, Compound 7-50 Oxysterols receptor LXR-beta 19.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304374&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554443 381753087 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583646 CC(C)[C@@H]1CN(CCN1c1nsc(n1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O InChI=1S/C17H21F3N4O2S2/c1-11(2)14-10-23(12-5-4-6-13(9-12)28(3,25)26)7-8-24(14)16-21-15(27-22-16)17(18,19)20/h4-6,9,11,14H,7-8,10H2,1-3H3/t14-/m0/s1 ZUTRFQWZXQEIBM-AWEZNQCLSA-N 304375 (R)-2-(2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-5-(trifluoromethyl)-1,3,4-thiadiazole::US10144715, Compound 7-51 Oxysterols receptor LXR-beta 22.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304375&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554444 381753088 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583648 CC(C)[C@@H]1CN(CCN1c1nc2ccccc2o1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H24FN3O3S/c1-14(2)18-13-24(15-8-9-16(22)20(12-15)29(3,26)27)10-11-25(18)21-23-17-6-4-5-7-19(17)28-21/h4-9,12,14,18H,10-11,13H2,1-3H3/t18-/m0/s1 UATPJWGKTPZRPL-SFHVURJKSA-N 304376 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)benzo[d]oxazole::US10144715, Compound 7-52 Oxysterols receptor LXR-beta 41.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304376&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554445 381753089 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583650 CC(C)[C@@H]1CN(CCN1c1nc2ccc(cc2s1)C#N)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H23FN4O2S2/c1-14(2)19-13-26(16-5-6-17(23)21(11-16)31(3,28)29)8-9-27(19)22-25-18-7-4-15(12-24)10-20(18)30-22/h4-7,10-11,14,19H,8-9,13H2,1-3H3/t19-/m0/s1 DKTPGSDKMSCAGJ-IBGZPJMESA-N 304377 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)benzo[d]thiazole-6-carbonitrile::US10144715, Compound 7-53 Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304377&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554446 381753090 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583653 CC(C)[C@@H]1CN(CCN1c1nc2c(F)cccc2s1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H23F2N3O2S2/c1-13(2)17-12-25(14-7-8-15(22)19(11-14)30(3,27)28)9-10-26(17)21-24-20-16(23)5-4-6-18(20)29-21/h4-8,11,13,17H,9-10,12H2,1-3H3/t17-/m0/s1 SKGJRIXOTUPIFB-KRWDZBQOSA-N 304378 (R)-4-fluoro-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)benzo[d]thiazole::US10144715, Compound 7-54 Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304378&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554447 381753091 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583655 CC(C)[C@@H]1CN(CCN1c1nc2ccc(F)cc2s1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H23F2N3O2S2/c1-13(2)18-12-25(15-5-6-16(23)20(11-15)30(3,27)28)8-9-26(18)21-24-17-7-4-14(22)10-19(17)29-21/h4-7,10-11,13,18H,8-9,12H2,1-3H3/t18-/m0/s1 FSWJCUCOFKYNQD-SFHVURJKSA-N 304379 (R)-6-fluoro-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)benzo[d]thiazole::US10144715, Compound 7-55 Oxysterols receptor LXR-beta 14.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304379&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554448 381753092 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583657 CC(C)[C@@H]1CN(CCN1c1nc2ccccc2s1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H24FN3O2S2/c1-14(2)18-13-24(15-8-9-16(22)20(12-15)29(3,26)27)10-11-25(18)21-23-17-6-4-5-7-19(17)28-21/h4-9,12,14,18H,10-11,13H2,1-3H3/t18-/m0/s1 RGPYRFIDCPYCJL-SFHVURJKSA-N 304380 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)benzo[d]thiazole::US10144715, Compound 7-56 Oxysterols receptor LXR-beta 15.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304380&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 130304941 381753093 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583659 CC(C)[C@@H]1CN(CCN1c1nc2cccnc2s1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23FN4O2S2/c1-13(2)17-12-24(14-6-7-15(21)18(11-14)29(3,26)27)9-10-25(17)20-23-16-5-4-8-22-19(16)28-20/h4-8,11,13,17H,9-10,12H2,1-3H3/t17-/m0/s1 JEZUXZJVPKBKJF-KRWDZBQOSA-N 304381 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)thiazolo[5,4-b]pyridine::US10144715, Compound 7-57 Oxysterols receptor LXR-beta 12.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304381&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883550 381753094 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583661 CC(C)[C@@H]1CN(CCN1c1nc2cnccc2s1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23FN4O2S2/c1-13(2)17-12-24(14-4-5-15(21)19(10-14)29(3,26)27)8-9-25(17)20-23-16-11-22-7-6-18(16)28-20/h4-7,10-11,13,17H,8-9,12H2,1-3H3/t17-/m0/s1 ZKBQZJVVWPDWDU-KRWDZBQOSA-N 304382 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)thiazolo[4,5-c]pyridine::US10144715, Compound 7-58 Oxysterols receptor LXR-beta 509 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304382&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554449 381753095 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583663 CC(C)[C@@H]1CN(CCN1c1nc2ncccc2s1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C20H23FN4O2S2/c1-13(2)16-12-24(14-6-7-15(21)18(11-14)29(3,26)27)9-10-25(16)20-23-19-17(28-20)5-4-8-22-19/h4-8,11,13,16H,9-10,12H2,1-3H3/t16-/m0/s1 YPGJKBPNUAZVOT-INIZCTEOSA-N 304383 (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)thiazolo[4,5-b]pyridine::US10144715, Compound 7-59 Oxysterols receptor LXR-beta 39.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304383&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554450 381753096 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583665 CC(C)[C@@H]1CN(CCN1c1nccc(n1)C(F)(F)F)c1cccc(c1)S(N)(=O)=O InChI=1S/C18H22F3N5O2S/c1-12(2)15-11-25(13-4-3-5-14(10-13)29(22,27)28)8-9-26(15)17-23-7-6-16(24-17)18(19,20)21/h3-7,10,12,15H,8-9,11H2,1-2H3,(H2,22,27,28)/t15-/m0/s1 DWVNDOKJFPRSRU-HNNXBMFYSA-N 304384 (R)-3-(3-isopropyl-4-(4-(trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)benzenesulfonamide::US10144715, Compound 7-60 Oxysterols receptor LXR-beta 146 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304384&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883441 381753097 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583668 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccc(F)cc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H20F4N4O2S/c1-33(31,32)18-4-2-3-17(13-18)29-11-12-30(19(14-29)15-5-7-16(23)8-6-15)21-27-10-9-20(28-21)22(24,25)26/h2-10,13,19H,11-12,14H2,1H3/t19-/m0/s1 YBOVOEBYAFAWAS-IBGZPJMESA-N 304385 (R)-2-(2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 8-1 Oxysterols receptor LXR-beta 36.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304385&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883504 381753098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583670 CS(=O)(=O)c1cccc(c1)N1CCN([C@@H](C1)c1ccc(F)cc1)c1nccc(n1)C(F)(F)F InChI=1S/C22H20F4N4O2S/c1-33(31,32)18-4-2-3-17(13-18)29-11-12-30(19(14-29)15-5-7-16(23)8-6-15)21-27-10-9-20(28-21)22(24,25)26/h2-10,13,19H,11-12,14H2,1H3/t19-/m0/s1 YBOVOEBYAFAWAS-IBGZPJMESA-N 304385 (R)-2-(2-(4-fluorophenyl)-4-(3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine::US10144715, Compound 8-1 Oxysterols receptor LXR-beta 62.0 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304385&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118883504 381753098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583672 CCOC(=O)c1nc(ncc1CC)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H31FN4O4S/c1-6-16-13-25-23(26-21(16)22(29)32-7-2)28-11-10-27(14-19(28)15(3)4)17-8-9-18(24)20(12-17)33(5,30)31/h8-9,12-13,15,19H,6-7,10-11,14H2,1-5H3/t19-/m0/s1 DGEWXSKODYXXLE-IBGZPJMESA-N 304386 US10144715, Compound 9-1::ethyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 13.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304386&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554451 381753099 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583674 COC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H24F4N4O4S/c1-12(2)16-11-28(13-5-6-15(22)17(9-13)34(4,31)32)7-8-29(16)20-26-10-14(19(30)33-3)18(27-20)21(23,24)25/h5-6,9-10,12,16H,7-8,11H2,1-4H3/t16-/m0/s1 COULHFBFGNXFAF-INIZCTEOSA-N 304387 US10144715, Compound 9-2::methyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 10.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304387&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554452 381753100 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583675 COC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C21H24F4N4O4S/c1-12(2)16-11-28(13-5-6-15(22)17(9-13)34(4,31)32)7-8-29(16)20-26-10-14(19(30)33-3)18(27-20)21(23,24)25/h5-6,9-10,12,16H,7-8,11H2,1-4H3/t16-/m0/s1 COULHFBFGNXFAF-INIZCTEOSA-N 304387 US10144715, Compound 9-2::methyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796173 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304387&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554452 381753100 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583676 COC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(F)c(c1)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C27H28F4N4O5S/c1-16(2)22-15-34(11-12-35(22)26-32-14-20(25(36)40-4)24(33-26)27(29,30)31)17-5-10-21(28)23(13-17)41(37,38)19-8-6-18(39-3)7-9-19/h5-10,13-14,16,22H,11-12,15H2,1-4H3/t22-/m0/s1 KMSBVORPSSIVNO-QFIPXVFZSA-N 304388 US10144715, Compound 9-3::methyl (R)-2-(4-(4-fluoro-3-(N-(4-methoxybenzyl)-N-methylsulfamoyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 16.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304388&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554453 381753101 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583677 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C1CC1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H24F4N4O4S/c1-3-34-20(31)15-11-27-21(28-19(15)22(24,25)26)30-9-8-29(12-17(30)13-4-5-13)14-6-7-16(23)18(10-14)35(2,32)33/h6-7,10-11,13,17H,3-5,8-9,12H2,1-2H3/t17-/m0/s1 NMPPSCVKLYVLOM-KRWDZBQOSA-N 304389 US10144715, Compound 9-4::ethyl (R)-2-(2-cyclopropyl-4-(4-fluoro-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 13.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304389&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554454 381753102 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583679 COC(=O)c1cnc(nc1C(F)(F)F)N1CCN(CC1C(C)(C)C)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C22H26F4N4O4S/c1-21(2,3)17-12-29(13-6-7-15(23)16(10-13)35(5,32)33)8-9-30(17)20-27-11-14(19(31)34-4)18(28-20)22(24,25)26/h6-7,10-11,17H,8-9,12H2,1-5H3 CRRQUBDXEDTMJH-UHFFFAOYSA-N 304390 US10144715, Compound 9-5::methyl 2-(2-(tert-butyl)-4-(4-fluoro-3-(methylsulfonyl)phenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 9.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304390&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554455 381753103 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583681 CNS(=O)(=O)c1cc(ccc1F)N1CCN([C@@H](C1)C(C)C)c1ncc(C(=O)OC)c(n1)C(F)(F)F InChI=1S/C21H25F4N5O4S/c1-12(2)16-11-29(13-5-6-15(22)17(9-13)35(32,33)26-3)7-8-30(16)20-27-10-14(19(31)34-4)18(28-20)21(23,24)25/h5-6,9-10,12,16,26H,7-8,11H2,1-4H3/t16-/m0/s1 WNHGOWAKQUWTHZ-INIZCTEOSA-N 304391 US10144715, Compound 9-6::methyl (R)-2-(4-(4-fluoro-3-(N-methylsulfamoyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 8.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304391&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554456 381753104 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583683 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)CC)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C23H28F4N4O4S/c1-5-14(3)18-13-30(15-7-8-17(24)19(11-15)36(4,33)34)9-10-31(18)22-28-12-16(21(32)35-6-2)20(29-22)23(25,26)27/h7-8,11-12,14,18H,5-6,9-10,13H2,1-4H3/t14?,18-/m0/s1 OVYOPGSHTATUOV-IBYPIGCZSA-N 304392 US10144715, Compound 9-7::ethyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-isobutylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 8.00 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304392&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554457 381753105 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583685 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1c1nc(C)cs1)c1cccc(c1)S(C)(=O)=O InChI=1S/C23H24F3N5O4S2/c1-4-35-21(32)17-11-27-22(29-19(17)23(24,25)26)31-9-8-30(12-18(31)20-28-14(2)13-36-20)15-6-5-7-16(10-15)37(3,33)34/h5-7,10-11,13,18H,4,8-9,12H2,1-3H3/t18-/m0/s1 NHBRTURIQHFEAQ-SFHVURJKSA-N 304393 US10144715, Compound 9-8::ethyl (S)-2-(4-(3-(methylsulfonyl)phenyl)-2-(4-methylthiazol-2-yl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 659 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304393&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554458 381753106 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583686 COC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1c1ccc(F)cc1)c1ccc(F)c(c1)S(C)(=O)=O InChI=1S/C24H21F5N4O4S/c1-37-22(34)17-12-30-23(31-21(17)24(27,28)29)33-10-9-32(13-19(33)14-3-5-15(25)6-4-14)16-7-8-18(26)20(11-16)38(2,35)36/h3-8,11-12,19H,9-10,13H2,1-2H3/t19-/m0/s1 FTZGSNAHAQXZOY-IBGZPJMESA-N 304394 US10144715, Compound 9-9::methyl (R)-2-(4-(4-fluoro-3-(methylsulfonyl)phenyl)-2-(4-fluorophenyl)piperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 298 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304394&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554459 381753107 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 583688 CCOC(=O)c1cnc(nc1C(F)(F)F)N1CCN(C[C@H]1C(C)C)c1ccc(CC(=O)OC)c(c1)S(C)(=O)=O InChI=1S/C25H31F3N4O6S/c1-6-38-23(34)18-13-29-24(30-22(18)25(26,27)28)32-10-9-31(14-19(32)15(2)3)17-8-7-16(11-21(33)37-4)20(12-17)39(5,35)36/h7-8,12-13,15,19H,6,9-11,14H2,1-5H3/t19-/m0/s1 UEJPCXIQFUDYBS-IBGZPJMESA-N 304395 US10144715, Compound 9-10::ethyl (R)-2-(4-(4-(acetoxymethyl)-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylate Oxysterols receptor LXR-beta 14.0 US Patent 10.7270/Q2PV6NFD aid1796172 US10144715 Claremon, DA; Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=304395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=304395&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137554460 381753108 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1007234 CC(CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F InChI=1S/C34H33ClF3NO3/c1-24(18-19-42-29-16-8-10-25(20-29)21-32(40)41)39(22-28-15-9-17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41) ZLJZDYOBXVOTSA-UHFFFAOYSA-N 426493 US10543183, Compound SB742881::US10669296, Compound SB742881::US10945978, Compound 25 Oxysterols receptor LXR-beta 25.0 US Patent 10.7270/Q2959MPZ aid1805335 US10945978 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=426493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=426493&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 68861577 434320823 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1007236 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 50.0 US Patent 10.7270/Q2959MPZ aid1805335 US10945978 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1007238 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta 24.0 US Patent 10.7270/Q2959MPZ aid1805335 US10945978 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1007240 CC(C)(O)c1cn(c(n1)C(C)(C)c1c(Cl)cccc1Cl)-c1ccc(cc1F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O InChI=1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3 HNAJDMYOTDNOBK-UHFFFAOYSA-N 50204072 CHEMBL3945199::US10543183, Compound 12::US10945978, Compound 12 Oxysterols receptor LXR-beta 11.0 US Patent 10.7270/Q2959MPZ aid1805335 US10945978 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 6OX 5JY3 49787490 375980324 CHEMBL3945199 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1007242 CC(C)(O)c1cn(c(n1)C(C)(C)c1ccccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3 JLPURTXCSILYLW-UHFFFAOYSA-N 50034775 CHEMBL3360975::US10543183, Compound 38::US10945978, Compound 38 Oxysterols receptor LXR-beta 630 US Patent 10.7270/Q2959MPZ aid1805335 US10945978 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 652 4RAK 59251511 313066503 CHEMBL3360975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738990 CC(C)Cn1nc(cc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C21H21F3N2O2S/c1-14(2)13-26-19(12-20(25-26)21(22,23)24)16-9-7-15(8-10-16)17-5-4-6-18(11-17)29(3,27)28/h4-12,14H,13H2,1-3H3 KESJWXSFVLYWPR-UHFFFAOYSA-N 372421 US10246419, Compound 4 Oxysterols receptor LXR-beta <1000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372421&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91663310 402359359 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738991 CC(C)Cn1nc(cc1-c1ccc(cc1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C22H23F3N2O3S/c1-14(2)12-27-19(11-21(26-27)22(23,24)25)16-6-4-15(5-7-16)17-8-9-18(13-28)20(10-17)31(3,29)30/h4-11,14,28H,12-13H2,1-3H3 CAGNSFIQAAPKNU-UHFFFAOYSA-N 372422 US10246419, Compound 5 Oxysterols receptor LXR-beta <1000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372422&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117940592 402359360 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738992 CC(C)Cn1nc(cc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(=O)NCC(F)(F)F InChI=1S/C23H24F3N3O3S/c1-15(2)13-29-21(12-20(28-29)22(30)27-14-23(24,25)26)17-9-7-16(8-10-17)18-5-4-6-19(11-18)33(3,31)32/h4-12,15H,13-14H2,1-3H3,(H,27,30) XRYPNGSZXWYDBI-UHFFFAOYSA-N 372423 US10246419, Compound 6 Oxysterols receptor LXR-beta <1000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372423&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117940574 402359361 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738993 CCOC(=O)c1cc(-c2ccc(cc2)-c2ccc(CO)c(c2)S(C)(=O)=O)n(CC(C)C)n1 InChI=1S/C24H28N2O5S/c1-5-31-24(28)21-13-22(26(25-21)14-16(2)3)18-8-6-17(7-9-18)19-10-11-20(15-27)23(12-19)32(4,29)30/h6-13,16,27H,5,14-15H2,1-4H3 MMZWTSPXMOSPGT-UHFFFAOYSA-N 372424 US10246419, Compound 10::US10246419, Compound 7 Oxysterols receptor LXR-beta <1000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372424&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951298 402359362 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738994 CCOC(=O)c1cn(c(CC(C)C)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O InChI=1S/C23H26N2O4S/c1-5-29-23(26)21-15-25(22(24-21)13-16(2)3)19-11-9-17(10-12-19)18-7-6-8-20(14-18)30(4,27)28/h6-12,14-16H,5,13H2,1-4H3 FAJJPPYLEGJRRA-UHFFFAOYSA-N 372425 US10246419, Compound 8 Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372425&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117940584 402359363 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738995 CC(C)Cn1nc(cc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(C)=C InChI=1S/C23H26N2O2S/c1-16(2)15-25-23(14-22(24-25)17(3)4)19-11-9-18(10-12-19)20-7-6-8-21(13-20)28(5,26)27/h6-14,16H,3,15H2,1-2,4-5H3 FIUSCDFFNFGFAZ-UHFFFAOYSA-N 372426 US10246419, Compound 9 Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372426&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117940594 402359364 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738996 CCOC(=O)c1cc(-c2ccc(cc2)-c2ccc(CO)c(c2)S(C)(=O)=O)n(CC(C)C)n1 InChI=1S/C24H28N2O5S/c1-5-31-24(28)21-13-22(26(25-21)14-16(2)3)18-8-6-17(7-9-18)19-10-11-20(15-27)23(12-19)32(4,29)30/h6-13,16,27H,5,14-15H2,1-4H3 MMZWTSPXMOSPGT-UHFFFAOYSA-N 372424 US10246419, Compound 10::US10246419, Compound 7 Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372424&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951298 402359362 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738997 CCOC(=O)c1cc(-c2ccc(cc2)-c2cccc(c2)S(C)(=O)=O)n(CC(C)C)n1 InChI=1S/C23H26N2O4S/c1-5-29-23(26)21-14-22(25(24-21)15-16(2)3)18-11-9-17(10-12-18)19-7-6-8-20(13-19)30(4,27)28/h6-14,16H,5,15H2,1-4H3 AHEKVZVJZSDBLW-UHFFFAOYSA-N 372428 US10246419, Compound 11 Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372428&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117940555 402359365 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738998 CC(C)Cn1nc(cc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(C)C InChI=1S/C23H28N2O2S/c1-16(2)15-25-23(14-22(24-25)17(3)4)19-11-9-18(10-12-19)20-7-6-8-21(13-20)28(5,26)27/h6-14,16-17H,15H2,1-5H3 KAQUIPIFOUCNLU-UHFFFAOYSA-N 372429 US10246419, Compound 12 Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372429&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951280 402359366 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 738999 CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1cc(nn1CC1CC1)C(F)(F)F InChI=1S/C21H19F3N2O2S/c1-29(27,28)18-4-2-3-17(11-18)15-7-9-16(10-8-15)19-12-20(21(22,23)24)25-26(19)13-14-5-6-14/h2-4,7-12,14H,5-6,13H2,1H3 PDXPRZYASKVVHS-UHFFFAOYSA-N 372430 1-(cyclopropylmethyl)- 5-(3'-(methylsulfonyl)- [1,1'-biphenyl]-4-yl)- 3-(trifluoromethyl)- 1H-pyrazole::US10246419, Compound 18 Oxysterols receptor LXR-beta <1000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372430&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951295 402359367 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 739000 CCC(C)n1nc(cc1-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O)C(F)(F)F InChI=1S/C21H21F3N2O2S/c1-4-14(2)26-19(13-20(25-26)21(22,23)24)16-10-8-15(9-11-16)17-6-5-7-18(12-17)29(3,27)28/h5-14H,4H2,1-3H3 DLOODBPNOCKXOA-UHFFFAOYSA-N 372431 1-(sec-butyl)-5-(3'- (methylsulfonyl)-[1,1'- biphenyl]-4-yl)-3- (trifluoromethyl)-1H- pyrazole::US10246419, Compound 19 Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372431&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951285 402359368 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 739001 CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1cc(nn1C1CCCCC1)C(F)(F)F InChI=1S/C23H23F3N2O2S/c1-31(29,30)20-9-5-6-18(14-20)16-10-12-17(13-11-16)21-15-22(23(24,25)26)27-28(21)19-7-3-2-4-8-19/h5-6,9-15,19H,2-4,7-8H2,1H3 NYXCHSJEOJUMBA-UHFFFAOYSA-N 372432 1-cyclohexyl-5-(3'- (methylsulfonyl)-[1,1'- biphenyl]-4-yl)-3- (trifluoromethyl)-1H- pyrazole::US10246419, Compound 20 Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372432&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951286 402359369 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 739002 CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-c1cc(nn1CC1CCCCC1)C(F)(F)F InChI=1S/C24H25F3N2O2S/c1-32(30,31)21-9-5-8-20(14-21)18-10-12-19(13-11-18)22-15-23(24(25,26)27)28-29(22)16-17-6-3-2-4-7-17/h5,8-15,17H,2-4,6-7,16H2,1H3 GFJQKJXMKVBAEW-UHFFFAOYSA-N 372433 US10246419, Compound 21 Oxysterols receptor LXR-beta <1000 US Patent 10.7270/Q2GT5QHJ aid1798183 US10246419 Mohan, R RALEXAR THERAPEUTICS, INC. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=372433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=372433&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117951281 402359370 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815598 CC(C)CC[C@@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1 RZPAXNJLEKLXNO-GFKLAVDKSA-N 20177 (1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::22(R)-hydroxycholesterol::CHEMBL422904 Oxysterols receptor LXR-beta 4750 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20177&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search HC9 3N9Z,3MZS,3L0J 167685 49688252 67237 CHEMBL422904 2742 C05502 ZINC04096816 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815599 CC[C@@H](C(C)C)[C@@H]1O[C@H]1[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H48O2/c1-7-21(17(2)3)27-26(31-27)18(4)23-10-11-24-22-9-8-19-16-20(30)12-14-28(19,5)25(22)13-15-29(23,24)6/h8,17-18,20-27,30H,7,9-16H2,1-6H3/t18-,20-,21-,22-,23+,24-,25-,26-,27-,28-,29+/m0/s1 WYBKKEVAPGOHJU-RYWLMXRFSA-N 50257930 CHEMBL4061349 Oxysterols receptor LXR-beta 12720 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257930&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137635446 402361333 C00722 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815601 CC(C)[C@@H](C)[C@H]1O[C@@H]1[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H44O2/c1-16(2)17(3)25-26(30-25)18(4)22-9-10-23-21-8-7-19-15-20(29)11-13-27(19,5)24(21)12-14-28(22,23)6/h7-8,16-18,20,22-26,29H,9-15H2,1-6H3/t17-,18+,20+,22-,23+,24+,25-,26-,27+,28-/m1/s1 QQLHWAKALUIDKJ-NDAXQORBSA-N 50257929 CHEMBL4097209 Oxysterols receptor LXR-beta 7200 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257929&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137659428 402361332 C00722 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815603 CC(C)[C@@H](C)[C@@H]1O[C@H]1[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H44O2/c1-16(2)17(3)25-26(30-25)18(4)22-9-10-23-21-8-7-19-15-20(29)11-13-27(19,5)24(21)12-14-28(22,23)6/h7-8,16-18,20,22-26,29H,9-15H2,1-6H3/t17-,18+,20+,22-,23+,24+,25+,26+,27+,28-/m1/s1 QQLHWAKALUIDKJ-MYXJCWLKSA-N 50257928 CHEMBL4070016 Oxysterols receptor LXR-beta 1960 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257928&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137638307 402361331 C00722 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815604 CC[C@H](C[C@@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C InChI=1S/C29H50O2/c1-7-20(18(2)3)16-27(31)19(4)24-10-11-25-23-9-8-21-17-22(30)12-14-28(21,5)26(23)13-15-29(24,25)6/h8,18-20,22-27,30-31H,7,9-17H2,1-6H3/t19-,20+,22-,23-,24+,25-,26-,27+,28-,29+/m0/s1 YCZQDKIUGZGCAN-JDVKSECFSA-N 50257937 CHEMBL4094610 Oxysterols receptor LXR-beta 2310 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257937&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118796406 402361340 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815608 CC(C)[C@@H](C)C[C@H](O)[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H46O2/c1-17(2)18(3)15-26(30)19(4)23-9-10-24-22-8-7-20-16-21(29)11-13-27(20,5)25(22)12-14-28(23,24)6/h7-8,17-19,21,23-26,29-30H,9-16H2,1-6H3/t18-,19-,21-,23+,24-,25-,26-,27-,28+/m0/s1 TWZNIUKPPRAQCW-FBFQPVLYSA-N 50257933 CHEMBL4086897 Oxysterols receptor LXR-beta 1960 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257933&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137643175 402361336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815616 CC[C@@H](C(C)C)[C@H]1O[C@@H]1[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H48O2/c1-7-21(17(2)3)27-26(31-27)18(4)23-10-11-24-22-9-8-19-16-20(30)12-14-28(19,5)25(22)13-15-29(23,24)6/h8,17-18,20-27,30H,7,9-16H2,1-6H3/t18-,20-,21-,22-,23+,24-,25-,26+,27+,28-,29+/m0/s1 WYBKKEVAPGOHJU-ZLZOMJGSSA-N 50257938 CHEMBL4089508 Oxysterols receptor LXR-beta 3790 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257938&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137641894 402361341 C00722 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815619 CC[C@@H](C(C)C)[C@H](O)C[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H50O2/c1-7-22(18(2)3)27(31)16-19(4)24-10-11-25-23-9-8-20-17-21(30)12-14-28(20,5)26(23)13-15-29(24,25)6/h8,18-19,21-27,30-31H,7,9-17H2,1-6H3/t19-,21+,22+,23+,24-,25+,26+,27-,28+,29-/m1/s1 FUWVBQKPDLWJQZ-RMPUYAGJSA-N 50257935 CHEMBL4067156 Oxysterols receptor LXR-beta 2700 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257935&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137634167 402361338 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50815620 CC[C@@H](C(C)C)C(=O)C[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H48O2/c1-7-22(18(2)3)27(31)16-19(4)24-10-11-25-23-9-8-20-17-21(30)12-14-28(20,5)26(23)13-15-29(24,25)6/h8,18-19,21-26,30H,7,9-17H2,1-6H3/t19-,21+,22+,23+,24-,25+,26+,28+,29-/m1/s1 GPONKGGQPMFNDI-AMPBYXCMSA-N 50257939 CHEMBL4078083 Oxysterols receptor LXR-beta 6020 ChEMBL 10.1021/acs.jmedchem.7b00091 10.7270/Q2GH9MDC 28741954 Marinozzi, M; Castro Navas, FF; Maggioni, D; Carosati, E; Bocci, G; Carloncelli, M; Giorgi, G; Cruciani, G; Fontana, R; Russo, V Universit£ degli Studi di Perugia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50257939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50257939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137651926 402361342 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 702005 CC(C)C1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C19H20F3N5O2S/c1-11(2)16-17-24-13-5-4-12(30(3,28)29)10-14(13)26(17)8-9-27(16)18-23-7-6-15(25-18)19(20,21)22/h4-7,10-11,16H,8-9H2,1-3H3 SEQLXXRHDQNPMX-UHFFFAOYSA-N 354727 1-isopropyl-7-(methylsulfonyl)-2-(4-(trifluoromethyl)pyrimidin-2-yl)-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine::US9814715, Example 1 Oxysterols receptor LXR-beta 256 US Patent 10.7270/Q23R0W1B aid1797590 US9814715 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharamceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=354727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=354727&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89815984 386394381 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 702007 CC(C)[C@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H22F3N5O3S/c1-11(2)17-18-25-13-8-12(10-29)15(32(3,30)31)9-14(13)27(18)6-7-28(17)19-24-5-4-16(26-19)20(21,22)23/h4-5,8-9,11,17,29H,6-7,10H2,1-3H3/t17-/m1/s1 CABUZECPUSGGRX-QGZVFWFLSA-N 155257 US9006244, E2a::US9814715, Example 2, isomer 1 Oxysterols receptor LXR-beta 20.0 US Patent 10.7270/Q23R0W1B aid1797590 US9814715 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharamceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155257&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735263 253658259 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 702009 CC(C)[C@@H]1N(CCn2c1nc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H22F3N5O3S/c1-11(2)17-18-25-13-8-12(10-29)15(32(3,30)31)9-14(13)27(18)6-7-28(17)19-24-5-4-16(26-19)20(21,22)23/h4-5,8-9,11,17,29H,6-7,10H2,1-3H3/t17-/m0/s1 CABUZECPUSGGRX-KRWDZBQOSA-N 155258 US9006244, E2b::US9814715, Example 2, isomer 2 Oxysterols receptor LXR-beta >2500 US Patent 10.7270/Q23R0W1B aid1797590 US9814715 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharamceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155258&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735264 253658260 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 702011 CC(C)[C@H]1N(CCn2c1cc1ccc(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H21F3N4O2S/c1-12(2)18-16-10-13-4-5-14(30(3,28)29)11-15(13)26(16)8-9-27(18)19-24-7-6-17(25-19)20(21,22)23/h4-7,10-12,18H,8-9H2,1-3H3/t18-/m1/s1 HKNRVRUCDFTKQI-GOSISDBHSA-N 155259 US9006244, E3a::US9814715, Example 3, isomer 1 Oxysterols receptor LXR-beta 27.0 US Patent 10.7270/Q23R0W1B aid1797590 US9814715 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharamceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155259&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735265 253658261 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 702013 CC(C)[C@@H]1N(CCn2c1cc1ccc(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C20H21F3N4O2S/c1-12(2)18-16-10-13-4-5-14(30(3,28)29)11-15(13)26(16)8-9-27(18)19-24-7-6-17(25-19)20(21,22)23/h4-7,10-12,18H,8-9H2,1-3H3/t18-/m0/s1 HKNRVRUCDFTKQI-SFHVURJKSA-N 155260 US9006244, E3b::US9814715, Example 3, isomer 2 Oxysterols receptor LXR-beta 1750 US Patent 10.7270/Q23R0W1B aid1797590 US9814715 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharamceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155260&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 89827883 253658262 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 702015 CC(C)[C@H]1N(CCn2c1cc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C21H23F3N4O3S/c1-12(2)19-16-9-13-8-14(11-29)17(32(3,30)31)10-15(13)27(16)6-7-28(19)20-25-5-4-18(26-20)21(22,23)24/h4-5,8-10,12,19,29H,6-7,11H2,1-3H3/t19-/m1/s1 XRWDAQASJVEARP-LJQANCHMSA-N 155261 US9006244, E4a::US9814715, Example 4, isomer 1 Oxysterols receptor LXR-beta 4.00 US Patent 10.7270/Q23R0W1B aid1797590 US9814715 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharamceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155261&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71722107 253658263 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 702017 CC(C)[C@@H]1N(CCn2c1cc1cc(CO)c(cc21)S(C)(=O)=O)c1nccc(n1)C(F)(F)F InChI=1S/C21H23F3N4O3S/c1-12(2)19-16-9-13-8-14(11-29)17(32(3,30)31)10-15(13)27(16)6-7-28(19)20-25-5-4-18(26-20)21(22,23)24/h4-5,8-10,12,19,29H,6-7,11H2,1-3H3/t19-/m0/s1 XRWDAQASJVEARP-IBGZPJMESA-N 155262 US9006244, E4b::US9814715, Example 4, isomer 2 Oxysterols receptor LXR-beta 846 US Patent 10.7270/Q23R0W1B aid1797590 US9814715 Dong, C; Fan, Y; Leftheris, K; Lotesta, SD; Singh, SB; Tice, CM; Zhao, W; Zheng, Y; Zhuang, L Vitae Pharamceuticals, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155262&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71735262 253658264 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50880765 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 800 ChEMBL 10.1016/j.bmcl.2017.01.066 10.7270/Q2668GNW 28169169 Heitel, P; Achenbach, J; Moser, D; Proschak, E; Merk, D Goethe-University Frankfurt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50880766 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta 900 ChEMBL 10.1016/j.bmcl.2017.01.066 10.7270/Q2668GNW 28169169 Heitel, P; Achenbach, J; Moser, D; Proschak, E; Merk, D Goethe-University Frankfurt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50880767 C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+ SHGAZHPCJJPHSC-ZVCIMWCZSA-N 31892 9-cis retinoic acid::9C-RA::CHEMBL705::Panretin::alitretinoin Oxysterols receptor LXR-beta 1730 ChEMBL 10.1016/j.bmcl.2017.01.066 10.7270/Q2668GNW 28169169 Heitel, P; Achenbach, J; Moser, D; Proschak, E; Merk, D Goethe-University Frankfurt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31892&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9CR 3LBD,1FM6,1FM9,6A60,3OAP,3UVV,5JI0,1XIU,6A5Y,6A5Z,1EPB,5UAN,1XLS,3DZU,3DZY,1TYR,1XDK,2NNH,4NQA,5Z12,1K74,3E00,1FBY,5M24 449171 85240518 26536 CHEMBL705 DB00523 2645 C15493 ZINC12661824 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50880771 Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26) NAVMQTYZDKMPEU-UHFFFAOYSA-N 50032675 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid::BEXAROTENE::CHEMBL1023::p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid Oxysterols receptor LXR-beta 434 ChEMBL 10.1016/j.bmcl.2017.01.066 10.7270/Q2668GNW 28169169 Heitel, P; Achenbach, J; Moser, D; Proschak, E; Merk, D Goethe-University Frankfurt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032675&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 9RA 3H0A,4K6I 82146 103941130 50859 CHEMBL1023 DB00307 2807 ZINC01539579 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50972394 CN1CC[C@H]([C@H](F)C1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O InChI=1S/C25H21ClF4N4O2S/c1-32-7-6-21(19(27)13-32)34-23(35)22(37-24(34)36)9-14-2-5-20-16(8-14)11-31-33(20)12-15-3-4-17(26)10-18(15)25(28,29)30/h2-5,8-11,19,21H,6-7,12-13H2,1H3/b22-9-/t19-,21-/m1/s1 BQNYTHNYGPJDQV-FHNILQQJSA-N 50276797 CHEMBL4174856 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.ejmech.2017.07.015 10.7270/Q2W098F7 28735214 Patch, RJ; Huang, H; Patel, S; Cheung, W; Xu, G; Zhao, BP; Beauchamp, DA; Rentzeperis, D; Geisler, JG; Askari, HB; Liu, J; Kasturi, J; Towers, M; Gaul, MD; Player, MR Janssen Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50276797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50276797&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 54597874 405257672 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 50972414 CN1CC[C@H]([C@H](F)C1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O InChI=1S/C25H21ClF4N4O2S/c1-32-7-6-21(19(27)13-32)34-23(35)22(37-24(34)36)9-14-2-5-20-16(8-14)11-31-33(20)12-15-3-4-17(26)10-18(15)25(28,29)30/h2-5,8-11,19,21H,6-7,12-13H2,1H3/b22-9-/t19-,21-/m1/s1 BQNYTHNYGPJDQV-FHNILQQJSA-N 50276797 CHEMBL4174856 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.ejmech.2017.07.015 10.7270/Q2W098F7 28735214 Patch, RJ; Huang, H; Patel, S; Cheung, W; Xu, G; Zhao, BP; Beauchamp, DA; Rentzeperis, D; Geisler, JG; Askari, HB; Liu, J; Kasturi, J; Towers, M; Gaul, MD; Player, MR Janssen Research and Development LLC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50276797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50276797&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 54597874 405257672 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51124471 CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OCC2CCOCC2)c(c1)[S@@](C)(=N)=O InChI=1S/C25H36N2O5S2/c1-5-20-6-8-22(9-7-20)27(17-19(2)3)34(29,30)23-10-11-24(25(16-23)33(4,26)28)32-18-21-12-14-31-15-13-21/h6-11,16,19,21,26H,5,12-15,17-18H2,1-4H3/t33-/m0/s1 OZSLLZRELNMFLA-XIFFEERXSA-N 50461063 CHEMBL4226803::US10457637, Compound 8 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2018.03.041 10.7270/Q2WD437Q 29571573 Ouvry, G; Bihl, F; Bouix-Peter, C; Christin, O; Defoin-Platel, C; Deret, S; Feret, C; Froude, D; Hacini-Rachinel, F; Harris, CS; Hervouet, C; Lafitte, G; Luzy, AP; Musicki, B; Orfila, D; Parnet, V; Pascau, C; Pascau, J; Pierre, R; Raffin, C; Rossio, P; Spiesse, D; Taquet, N; Thoreau, E; Vatinel, R; Vial, E; Hennequin, LF Nestle Skin Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50461063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50461063&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 121429517 433928328 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113517 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1Oc1ccccc1 InChI=1S/C20H9Cl4NO3/c21-15-13-14(16(22)18(24)17(15)23)20(27)25(19(13)26)11-8-4-5-9-12(11)28-10-6-2-1-3-7-10/h1-9H NPERBFXPZDADED-UHFFFAOYSA-N 50454832 CHEMBL4212022 Oxysterols receptor LXR-beta 8980 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454832&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145966450 433923053 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113519 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 21 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113520 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1CCc1ccccc1 InChI=1S/C22H13Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-9-5-4-8-13(14)11-10-12-6-2-1-3-7-12/h1-9H,10-11H2 FKRZWNNFTCLNFL-UHFFFAOYSA-N 50298686 4,5,6,7-Tetrachloro-N-[2-(2-phenylethyl)phenyl]phthalimide::CHEMBL574310 Oxysterols receptor LXR-beta 4980 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298686&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 45481825 104140215 CHEMBL574310 ZINC45284857 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113521 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1-c1ccccc1 InChI=1S/C20H9Cl4NO2/c21-15-13-14(16(22)18(24)17(15)23)20(27)25(19(13)26)12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9H DOIMMVIRDRVFHE-UHFFFAOYSA-N 50454833 CHEMBL4207540 Oxysterols receptor LXR-beta 1730 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454833&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 316046 433923054 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113522 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1Cc1ccccc1 InChI=1S/C21H11Cl4NO2/c22-16-14-15(17(23)19(25)18(16)24)21(28)26(20(14)27)13-9-5-4-8-12(13)10-11-6-2-1-3-7-11/h1-9H,10H2 DBWZHVPXGSXIOF-UHFFFAOYSA-N 50454834 CHEMBL4213362 Oxysterols receptor LXR-beta 8000 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454834&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145964868 433923055 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113523 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1cccnc1 InChI=1S/C21H10Cl4N2O2/c22-16-14-15(17(23)19(25)18(16)24)21(29)27(20(14)28)13-6-2-1-5-12(13)8-7-11-4-3-9-26-10-11/h1-10H/b8-7+ OIIWVSKXOPXSPQ-BQYQJAHWSA-N 50454835 CHEMBL4214029 Oxysterols receptor LXR-beta 4960 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454835&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145965139 433923056 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113524 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1ccncc1 InChI=1S/C21H10Cl4N2O2/c22-16-14-15(17(23)19(25)18(16)24)21(29)27(20(14)28)13-4-2-1-3-12(13)6-5-11-7-9-26-10-8-11/h1-10H/b6-5+ YAJRAHXZNPLUDN-AATRIKPKSA-N 50454836 CHEMBL4218494 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454836&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145967545 433923057 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113525 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1cccs1 InChI=1S/C20H9Cl4NO2S/c21-15-13-14(16(22)18(24)17(15)23)20(27)25(19(13)26)12-6-2-1-4-10(12)7-8-11-5-3-9-28-11/h1-9H/b8-7+ CSRGGIVFZAJPIC-BQYQJAHWSA-N 50454837 CHEMBL4217784 Oxysterols receptor LXR-beta 559 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454837&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145974975 433923058 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113529 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C/c1ccccc1 InChI=1S/C22H11Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-9-5-4-8-13(14)11-10-12-6-2-1-3-7-12/h1-11H/b11-10- JBICFNBLMNOMNL-KHPPLWFESA-N 50454840 CHEMBL4208321 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454840&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145975021 433923061 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113530 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1nccs1 InChI=1S/C19H8Cl4N2O2S/c20-14-12-13(15(21)17(23)16(14)22)19(27)25(18(12)26)10-4-2-1-3-9(10)5-6-11-24-7-8-28-11/h1-8H/b6-5+ PRWXVIIRASLOJH-AATRIKPKSA-N 50454841 CHEMBL4204457 Oxysterols receptor LXR-beta 3610 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454841&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145975104 433923062 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113532 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1ccccc1 InChI=1S/C22H11Cl4NO2/c23-17-15-16(18(24)20(26)19(17)25)22(29)27(21(15)28)14-9-5-4-8-13(14)11-10-12-6-2-1-3-7-12/h1-11H/b11-10+ JBICFNBLMNOMNL-ZHACJKMWSA-N 50454838 CHEMBL4215604 Oxysterols receptor LXR-beta 270 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454838&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145974164 433923059 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113533 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1ccccn1 InChI=1S/C21H10Cl4N2O2/c22-16-14-15(17(23)19(25)18(16)24)21(29)27(20(14)28)13-7-2-1-5-11(13)8-9-12-6-3-4-10-26-12/h1-10H/b9-8+ OTCUXMLGBFIFKI-CMDGGOBGSA-N 50454842 CHEMBL4215929 Oxysterols receptor LXR-beta 4770 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454842&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145973265 433923063 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113534 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1ccsc1 InChI=1S/C20H9Cl4NO2S/c21-15-13-14(16(22)18(24)17(15)23)20(27)25(19(13)26)12-4-2-1-3-11(12)6-5-10-7-8-28-9-10/h1-9H/b6-5+ KCFGMUPMJUNNCN-AATRIKPKSA-N 50454839 CHEMBL4217636 Oxysterols receptor LXR-beta 915 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454839&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145973564 433923060 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51113536 Clc1c2C(=O)N(C(=O)c2c(Cl)c(Cl)c1Cl)c1ccccc1\C=C\c1ccco1 InChI=1S/C20H9Cl4NO3/c21-15-13-14(16(22)18(24)17(15)23)20(27)25(19(13)26)12-6-2-1-4-10(12)7-8-11-5-3-9-28-11/h1-9H/b8-7+ WHTFBJRAHGKNHD-BQYQJAHWSA-N 50454843 CHEMBL4215212 Oxysterols receptor LXR-beta 4670 ChEMBL 10.1016/j.bmcl.2017.12.024 10.7270/Q2125W8V 29398545 Nomura, S; Endo-Umeda, K; Fujii, S; Makishima, M; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454843&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145972771 433923064 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109286 OC(c1ccc2N(CCSc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F7NO3S2/c18-11-2-4-12(5-3-11)30(27,28)25-7-8-29-14-9-10(1-6-13(14)25)15(26,16(19,20)21)17(22,23)24/h1-6,9,26H,7-8H2 NMKUHNALTSCROZ-UHFFFAOYSA-N 50452782 CHEMBL4210791 Oxysterols receptor LXR-beta 185 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452782&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145966156 433921598 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109287 OC(c1ccc2N(CCNc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H13F7N2O3S/c18-11-2-4-12(5-3-11)30(28,29)26-8-7-25-13-9-10(1-6-14(13)26)15(27,16(19,20)21)17(22,23)24/h1-6,9,25,27H,7-8H2 ZVRXQJVIPWKPHC-UHFFFAOYSA-N 50452795 CHEMBL4208087 Oxysterols receptor LXR-beta 445 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452795&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145977465 433921611 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109288 CN1CCN(c2ccc(cc12)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C18H15F7N2O3S/c1-26-8-9-27(31(29,30)13-5-3-12(19)4-6-13)14-7-2-11(10-15(14)26)16(28,17(20,21)22)18(23,24)25/h2-7,10,28H,8-9H2,1H3 ADKOPWFCGKLXMN-UHFFFAOYSA-N 50452796 CHEMBL4217418 Oxysterols receptor LXR-beta 455 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452796&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145974494 433921612 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109289 CC1CCN(c2ccc(cc12)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C19H16F7NO3S/c1-11-8-9-27(31(29,30)14-5-3-13(20)4-6-14)16-7-2-12(10-15(11)16)17(28,18(21,22)23)19(24,25)26/h2-7,10-11,28H,8-9H2,1H3 VCMYLRPKPWPXLZ-UHFFFAOYSA-N 50452787 CHEMBL4209665 Oxysterols receptor LXR-beta 130 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452787&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145963820 433921603 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109290 NC(=O)CC1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C19H15F7N2O4S2/c20-11-2-4-13(5-3-11)34(31,32)28-9-12(8-16(27)29)33-15-7-10(1-6-14(15)28)17(30,18(21,22)23)19(24,25)26/h1-7,12,30H,8-9H2,(H2,27,29) KBDBIOMGAWEQRR-UHFFFAOYSA-N 50452785 CHEMBL4213493 Oxysterols receptor LXR-beta 2820 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452785&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145967002 433921601 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109291 CNC(=O)CC1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C20H17F7N2O4S2/c1-28-17(30)9-13-10-29(35(32,33)14-5-3-12(21)4-6-14)15-7-2-11(8-16(15)34-13)18(31,19(22,23)24)20(25,26)27/h2-8,13,31H,9-10H2,1H3,(H,28,30) OOFNAQQSGDHAKY-UHFFFAOYSA-N 50452789 CHEMBL4214020 Oxysterols receptor LXR-beta 2470 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452789&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145964673 433921605 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109292 OC1CN(C1)C(=O)CC1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C22H19F7N2O5S2/c23-13-2-4-16(5-3-13)38(35,36)31-11-15(8-19(33)30-9-14(32)10-30)37-18-7-12(1-6-17(18)31)20(34,21(24,25)26)22(27,28)29/h1-7,14-15,32,34H,8-11H2 SVUOYTIFRCILRV-UHFFFAOYSA-N 50452792 CHEMBL4209808 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452792&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145965669 433921608 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109293 CC(C)(O)CNC(=O)CC1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C23H23F7N2O5S2/c1-20(2,34)12-31-19(33)10-15-11-32(39(36,37)16-6-4-14(24)5-7-16)17-8-3-13(9-18(17)38-15)21(35,22(25,26)27)23(28,29)30/h3-9,15,34-35H,10-12H2,1-2H3,(H,31,33) XUCORPNQMQOUMD-UHFFFAOYSA-N 50452784 CHEMBL4214711 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452784&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search XGH 6BN6,6BNS 145971562 433921600 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109294 CC(C)(O)CNC(=O)C[C@@H]1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C23H23F7N2O5S2/c1-20(2,34)12-31-19(33)10-15-11-32(39(36,37)16-6-4-14(24)5-7-16)17-8-3-13(9-18(17)38-15)21(35,22(25,26)27)23(28,29)30/h3-9,15,34-35H,10-12H2,1-2H3,(H,31,33)/t15-/m1/s1 XUCORPNQMQOUMD-OAHLLOKOSA-N 50452797 CHEMBL4213534 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452797&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145965344 433921613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109295 CC(C)(O)CNC(=O)CC1CSc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H23F7N2O5S2/c1-20(2,34)12-31-19(33)10-15-11-38-18-9-13(21(35,22(25,26)27)23(28,29)30)3-8-17(18)32(15)39(36,37)16-6-4-14(24)5-7-16/h3-9,15,34-35H,10-12H2,1-2H3,(H,31,33) DUBUCROMSYFQOW-UHFFFAOYSA-N 327745 (�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]thiazin-3-yl)-N-(2-hydroxy-2-methylpropyl)acetamide::US9663469, 292 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=327745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=327745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117950226 384582677 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109296 CC(C)(O)CNC(=O)CC1CSc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H23F7N2O5S2/c1-20(2,34)12-31-19(33)10-15-11-38-18-9-13(21(35,22(25,26)27)23(28,29)30)3-8-17(18)32(15)39(36,37)16-6-4-14(24)5-7-16/h3-9,15,34-35H,10-12H2,1-2H3,(H,31,33) DUBUCROMSYFQOW-UHFFFAOYSA-N 327745 (�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]thiazin-3-yl)-N-(2-hydroxy-2-methylpropyl)acetamide::US9663469, 292 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=327745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=327745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117950226 384582677 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109297 CC(C)(O)CNC(=O)C[C@H]1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C24H25F7N2O5S/c1-21(2,35)13-32-20(34)12-17-7-3-14-11-15(22(36,23(26,27)28)24(29,30)31)4-10-19(14)33(17)39(37,38)18-8-5-16(25)6-9-18/h4-6,8-11,17,35-36H,3,7,12-13H2,1-2H3,(H,32,34)/t17-/m1/s1 WKDNXLPZDBZVOG-QGZVFWFLSA-N 50452798 CHEMBL4204747 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452798&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145975835 433921614 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109340 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 198 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109341 CC(C)(O)CNC(=O)CC1CSc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C23H23F7N2O5S2/c1-20(2,34)12-31-19(33)10-15-11-38-18-9-13(21(35,22(25,26)27)23(28,29)30)3-8-17(18)32(15)39(36,37)16-6-4-14(24)5-7-16/h3-9,15,34-35H,10-12H2,1-2H3,(H,31,33) DUBUCROMSYFQOW-UHFFFAOYSA-N 327745 (�) 2-(4-((4-fluorophenyl)sulfonyl)-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]thiazin-3-yl)-N-(2-hydroxy-2-methylpropyl)acetamide::US9663469, 292 Oxysterols receptor LXR-beta 3710 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=327745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=327745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117950226 384582677 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109344 OC(c1ccc2N(CC(CC(=O)Nc3nncs3)Sc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C21H15F7N4O4S3/c22-12-2-4-14(5-3-12)39(35,36)32-9-13(8-17(33)30-18-31-29-10-37-18)38-16-7-11(1-6-15(16)32)19(34,20(23,24)25)21(26,27)28/h1-7,10,13,34H,8-9H2,(H,30,31,33) VZANPRWREWRZMY-UHFFFAOYSA-N 50452790 CHEMBL4209091 Oxysterols receptor LXR-beta 2900 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452790&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145965870 433921606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109345 OC(c1ccc2N(CC(CC(=O)Nc3ccncc3)Sc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C24H18F7N3O4S2/c25-15-2-4-18(5-3-15)40(37,38)34-13-17(12-21(35)33-16-7-9-32-10-8-16)39-20-11-14(1-6-19(20)34)22(36,23(26,27)28)24(29,30)31/h1-11,17,36H,12-13H2,(H,32,33,35) YOFKGHWSZHDQNO-UHFFFAOYSA-N 50452808 CHEMBL4216643 Oxysterols receptor LXR-beta 3120 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452808&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145973516 433921624 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109364 OC(c1ccc2N(CCOc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F7NO4S/c18-11-2-4-12(5-3-11)30(27,28)25-7-8-29-14-9-10(1-6-13(14)25)15(26,16(19,20)21)17(22,23)24/h1-6,9,26H,7-8H2 REOZCXVKAAJOFL-UHFFFAOYSA-N 50452786 CHEMBL4212995 Oxysterols receptor LXR-beta 340 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452786&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145965098 433921602 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109365 OC(=O)CC1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C19H14F7NO5S2/c20-11-2-4-13(5-3-11)34(31,32)27-9-12(8-16(28)29)33-15-7-10(1-6-14(15)27)17(30,18(21,22)23)19(24,25)26/h1-7,12,30H,8-9H2,(H,28,29) UOXQKFLDAXTYKE-UHFFFAOYSA-N 50452806 CHEMBL4218423 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452806&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145968478 433921622 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109368 CC1(C)CCN(c2ccc(cc12)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C20H18F7NO3S/c1-17(2)9-10-28(32(30,31)14-6-4-13(21)5-7-14)16-8-3-12(11-15(16)17)18(29,19(22,23)24)20(25,26)27/h3-8,11,29H,9-10H2,1-2H3 IFPBFPWEKKDYCO-UHFFFAOYSA-N 50452788 CHEMBL4206412 Oxysterols receptor LXR-beta 550 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452788&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145977892 433921604 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109375 COC(=O)CC1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C20H16F7NO5S2/c1-33-17(29)9-13-10-28(35(31,32)14-5-3-12(21)4-6-14)15-7-2-11(8-16(15)34-13)18(30,19(22,23)24)20(25,26)27/h2-8,13,30H,9-10H2,1H3 XSVGKHXBWUUWFX-UHFFFAOYSA-N 50452807 CHEMBL4217890 Oxysterols receptor LXR-beta 370 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452807&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145974767 433921623 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109376 CC(C)(O)CNC(=O)CC1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C24H25F7N2O5S/c1-21(2,35)13-32-20(34)12-17-7-3-14-11-15(22(36,23(26,27)28)24(29,30)31)4-10-19(14)33(17)39(37,38)18-8-5-16(25)6-9-18/h4-6,8-11,17,35-36H,3,7,12-13H2,1-2H3,(H,32,34) WKDNXLPZDBZVOG-UHFFFAOYSA-N 327532 (�) 2-(1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,2,3,4-tetrahydroquinolin-2-yl)-N-(2-hydroxy-2-methylpropyl)acetamide::US9663469, 71 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=327532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=327532&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117940657 384582476 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109379 CC(C)(O)CNC(=O)C[C@H]1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C23H23F7N2O5S2/c1-20(2,34)12-31-19(33)10-15-11-32(39(36,37)16-6-4-14(24)5-7-16)17-8-3-13(9-18(17)38-15)21(35,22(25,26)27)23(28,29)30/h3-9,15,34-35H,10-12H2,1-2H3,(H,31,33)/t15-/m0/s1 XUCORPNQMQOUMD-HNNXBMFYSA-N 50452793 CHEMBL4214210 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452793&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search XGH 6BN6,6BNS 131953519 433921609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109381 OC(c1ccc2N(CC(CC(=O)N3CCOCC3)Sc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C23H21F7N2O5S2/c24-15-2-4-17(5-3-15)39(35,36)32-13-16(12-20(33)31-7-9-37-10-8-31)38-19-11-14(1-6-18(19)32)21(34,22(25,26)27)23(28,29)30/h1-6,11,16,34H,7-10,12-13H2 FLXMKXZJQCUECV-UHFFFAOYSA-N 50452791 CHEMBL4205428 Oxysterols receptor LXR-beta 2450 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452791&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145976113 433921607 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109382 CC(C)(O)CC(=O)NCC1CN(c2ccc(cc2S1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C23H23F7N2O5S2/c1-20(2,34)10-19(33)31-11-15-12-32(39(36,37)16-6-4-14(24)5-7-16)17-8-3-13(9-18(17)38-15)21(35,22(25,26)27)23(28,29)30/h3-9,15,34-35H,10-12H2,1-2H3,(H,31,33) RHLFGMGTNLPFMT-UHFFFAOYSA-N 50452804 CHEMBL4218626 Oxysterols receptor LXR-beta 1040 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452804&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145969403 433921620 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109383 CC(C)(O)CNC(=O)C[C@@H]1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C24H25F7N2O5S/c1-21(2,35)13-32-20(34)12-17-7-3-14-11-15(22(36,23(26,27)28)24(29,30)31)4-10-19(14)33(17)39(37,38)18-8-5-16(25)6-9-18/h4-6,8-11,17,35-36H,3,7,12-13H2,1-2H3,(H,32,34)/t17-/m0/s1 WKDNXLPZDBZVOG-KRWDZBQOSA-N 50452794 CHEMBL4215334 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452794&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145974156 433921610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51098522 Cc1cc(cc2c1n(C)c(=O)c1cc(F)ccc21)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C18H12F7NO2/c1-8-5-9(16(28,17(20,21)22)18(23,24)25)6-12-11-4-3-10(19)7-13(11)15(27)26(2)14(8)12/h3-7,28H,1-2H3 XDFUKFMDLRMNOJ-UHFFFAOYSA-N 50367097 CHEMBL4173799 Oxysterols receptor LXR-beta >20000 ChEMBL 10.1021/acsmedchemlett.8b00058 10.7270/Q2PN986S 30034593 Nishiyama, Y; Mori, S; Makishima, M; Fujii, S; Kagechika, H; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145951022 160846199 ZINC95538231 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51098554 Cc1cc(cc2c1[nH]c(=O)c1ccccc21)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H11F6NO2/c1-8-6-9(15(26,16(18,19)20)17(21,22)23)7-12-10-4-2-3-5-11(10)14(25)24-13(8)12/h2-7,26H,1H3,(H,24,25) ZJIJGQSUYGWVGU-UHFFFAOYSA-N 50367063 CHEMBL4174199 Oxysterols receptor LXR-beta >20000 ChEMBL 10.1021/acsmedchemlett.8b00058 10.7270/Q2PN986S 30034593 Nishiyama, Y; Mori, S; Makishima, M; Fujii, S; Kagechika, H; Hashimoto, Y; Ishikawa, M The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367063&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145949340 160846165 ZINC05163062 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109270 OC(c1ccc2N(CCCc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C18H14F7NO3S/c19-13-4-6-14(7-5-13)30(28,29)26-9-1-2-11-10-12(3-8-15(11)26)16(27,17(20,21)22)18(23,24)25/h3-8,10,27H,1-2,9H2 VDGMDLWYOUANBX-UHFFFAOYSA-N 50452783 CHEMBL4212458 Oxysterols receptor LXR-beta 223 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452783&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 129167185 433921599 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51109271 CC(C)(O)[C@H](F)CNC(=O)C[C@@H]1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C25H26F8N2O5S/c1-22(2,37)20(27)13-34-21(36)12-17-7-3-14-11-15(23(38,24(28,29)30)25(31,32)33)4-10-19(14)35(17)41(39,40)18-8-5-16(26)6-9-18/h4-6,8-11,17,20,37-38H,3,7,12-13H2,1-2H3,(H,34,36)/t17-,20+/m0/s1 FQWMGYJHFABALZ-FXAWDEMLSA-N 327473 N—((S)-2-fluoro-3-hydroxy-3-methylbutyl)-2-((S)-1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,2,3,4-tetrahydroquinolin-2-yl)acetamide::US9663469, 14 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2017.12.006 10.7270/Q2862K0Z 29233651 Gong, H; Weinstein, DS; Lu, Z; Duan, JJ; Stachura, S; Haque, L; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Khan, J; Camac, D; Sack, JS; Pudzianowski, A; Wu, DR; Yarde, M; Shen, DR; Borowski, V; Xie, JH; Sun, H; D'Arienzo, C; Dabros, M; Galella, MA; Wang, F; Weigelt, CA; Zhao, Q; Foster, W; Somerville, JE; Salter-Cid, LM; Barrish, JC; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=327473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=327473&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 117949985 384582417 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51137269 CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(F)c2)C(C)(C)C(=O)Nc2ccc(F)cc2F)cc1 InChI=1S/C26H25F3N2O4S/c1-4-36(34,35)19-9-5-16(6-10-19)13-24(32)30-18-8-11-20(21(28)15-18)26(2,3)25(33)31-23-12-7-17(27)14-22(23)29/h5-12,14-15H,4,13H2,1-3H3,(H,30,32)(H,31,33) DZUAIKQCQQBQJM-UHFFFAOYSA-N 50466375 CHEMBL4287674 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2018.09.032 10.7270/Q2H997XS 30301676 Sasaki, Y; Odan, M; Yamamoto, S; Kida, S; Ueyama, A; Shimizu, M; Haruna, T; Watanabe, A; Okuno, T Shionogi & Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466375&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137796283 433933640 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51135636 CC(OC(=O)c1oc2cc(F)ccc2c1C)C(=O)N1CCNC1=O InChI=1S/C16H15FN2O5/c1-8-11-4-3-10(17)7-12(11)24-13(8)15(21)23-9(2)14(20)19-6-5-18-16(19)22/h3-4,7,9H,5-6H2,1-2H3,(H,18,22) SMRPARLQNTVFLB-UHFFFAOYSA-N 50465710 CHEMBL4289727 Oxysterols receptor LXR-beta 720 ChEMBL 10.1021/acs.jmedchem.8b00045 10.7270/Q2SX6GX7 30004226 El-Gendy, BEM; Goher, SS; Hegazy, LS; Arief, MMH; Burris, TP Saint Louis University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465710&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145989300 433932975 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51135638 CS(=O)(=O)c1cccc(c1)-c1ccc(s1)-c1cc(nn1-c1ccccc1Cl)C(F)(F)F InChI=1S/C21H14ClF3N2O2S2/c1-31(28,29)14-6-4-5-13(11-14)18-9-10-19(30-18)17-12-20(21(23,24)25)26-27(17)16-8-3-2-7-15(16)22/h2-12H,1H3 DIRKHQVAVLSYMA-UHFFFAOYSA-N 50034786 CHEMBL3360964 Oxysterols receptor LXR-beta 108 ChEMBL 10.1021/acs.jmedchem.8b00045 10.7270/Q2SX6GX7 30004226 El-Gendy, BEM; Goher, SS; Hegazy, LS; Arief, MMH; Burris, TP Saint Louis University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034786&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 59632482 313066514 CHEMBL3360964 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51135639 CN(CC(=O)Nc1ccc(F)c(F)c1F)C(=O)c1ccc2OCCOc2c1 InChI=1S/C18H15F3N2O4/c1-23(9-15(24)22-12-4-3-11(19)16(20)17(12)21)18(25)10-2-5-13-14(8-10)27-7-6-26-13/h2-5,8H,6-7,9H2,1H3,(H,22,24) XITZPIXICJOKTF-UHFFFAOYSA-N 50465711 CHEMBL1316881 Oxysterols receptor LXR-beta 530 ChEMBL 10.1021/acs.jmedchem.8b00045 10.7270/Q2SX6GX7 30004226 El-Gendy, BEM; Goher, SS; Hegazy, LS; Arief, MMH; Burris, TP Saint Louis University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465711&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 8001903 433932976 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51135644 CCOC(=O)c1ccc(CN(Cc2ccc(cc2)-c2cccc(c2)S(C)(=O)=O)S(=O)(=O)c2c(C)cc(C)cc2C)o1 InChI=1S/C31H33NO7S2/c1-6-38-31(33)29-15-14-27(39-29)20-32(41(36,37)30-22(3)16-21(2)17-23(30)4)19-24-10-12-25(13-11-24)26-8-7-9-28(18-26)40(5,34)35/h7-18H,6,19-20H2,1-5H3 HDZWHJYZJWLTAG-UHFFFAOYSA-N 50465712 CHEMBL4284414 Oxysterols receptor LXR-beta 43 ChEMBL 10.1021/acs.jmedchem.8b00045 10.7270/Q2SX6GX7 30004226 El-Gendy, BEM; Goher, SS; Hegazy, LS; Arief, MMH; Burris, TP Saint Louis University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465712&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71478195 433932977 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51137319 CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)C(C)(C)C(=O)Nc2ccc(F)cc2)cc1 InChI=1S/C26H27FN2O4S/c1-4-34(32,33)23-15-5-18(6-16-23)17-24(30)28-21-11-7-19(8-12-21)26(2,3)25(31)29-22-13-9-20(27)10-14-22/h5-16H,4,17H2,1-3H3,(H,28,30)(H,29,31) KUBGKOCHEJNDBQ-UHFFFAOYSA-N 50466382 CHEMBL4289622 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2018.09.032 10.7270/Q2H997XS 30301676 Sasaki, Y; Odan, M; Yamamoto, S; Kida, S; Ueyama, A; Shimizu, M; Haruna, T; Watanabe, A; Okuno, T Shionogi & Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466382&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145232219 433933647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51137320 CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(F)c2)C(C)(C)C(=O)Nc2ccc(F)cc2)cc1 InChI=1S/C26H26F2N2O4S/c1-4-35(33,34)21-12-5-17(6-13-21)15-24(31)29-20-11-14-22(23(28)16-20)26(2,3)25(32)30-19-9-7-18(27)8-10-19/h5-14,16H,4,15H2,1-3H3,(H,29,31)(H,30,32) JCIWZUTVGHDCLP-UHFFFAOYSA-N 50466367 CHEMBL4290041 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2018.09.032 10.7270/Q2H997XS 30301676 Sasaki, Y; Odan, M; Yamamoto, S; Kida, S; Ueyama, A; Shimizu, M; Haruna, T; Watanabe, A; Okuno, T Shionogi & Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466367&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145987785 433933632 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51137336 CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(F)c2)C(C)(C)C(=O)Nc2cc(ccn2)C#N)cc1 InChI=1S/C26H25FN4O4S/c1-4-36(34,35)20-8-5-17(6-9-20)14-24(32)30-19-7-10-21(22(27)15-19)26(2,3)25(33)31-23-13-18(16-28)11-12-29-23/h5-13,15H,4,14H2,1-3H3,(H,30,32)(H,29,31,33) DUHFUKXNEHGMID-UHFFFAOYSA-N 50466377 CHEMBL4279772 Oxysterols receptor LXR-beta >30000 ChEMBL 10.1016/j.bmcl.2018.09.032 10.7270/Q2H997XS 30301676 Sasaki, Y; Odan, M; Yamamoto, S; Kida, S; Ueyama, A; Shimizu, M; Haruna, T; Watanabe, A; Okuno, T Shionogi & Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466377&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145980094 433933642 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 859988 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta 24.0 US Patent 10.7270/Q2JW8H8C aid1804094 US10543183 Tavazoie, SF; Pencheva, N The Rockefeller University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260571 CN1CCN(Cc2ccc(N)cc2C(F)(F)F)CC1 InChI=1S/C13H18F3N3/c1-18-4-6-19(7-5-18)9-10-2-3-11(17)8-12(10)13(14,15)16/h2-3,8H,4-7,9,17H2,1H3 ZMWAZMYBMAAMAW-UHFFFAOYSA-N 50515022 CHEMBL4483515 Oxysterols receptor LXR-beta 99000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515022&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 46838908 440723604 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260572 COc1ccc(OC)c(Cl)c1 InChI=1S/C8H9ClO2/c1-10-6-3-4-8(11-2)7(9)5-6/h3-5H,1-2H3 QMXZSRVFIWACJH-UHFFFAOYSA-N 50515023 CHEMBL4561202 Oxysterols receptor LXR-beta 1028000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515023&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 246724 440723605 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260573 CC(=O)c1c(C)ccc2ccccc12 InChI=1S/C13H12O/c1-9-7-8-11-5-3-4-6-12(11)13(9)10(2)14/h3-8H,1-2H3 KFTUKCVZQBDUEY-UHFFFAOYSA-N 50515024 CHEMBL4558933 Oxysterols receptor LXR-beta 153000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515024&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 13659563 440723606 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260574 C[C@H](CCC(=O)NCCCCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C51H65N3O8S/c1-29(36-15-16-37-34-28-43(58)42-25-33(57)18-20-50(42,3)38(34)19-21-49(36,37)2)8-17-46(59)52-22-6-4-5-7-23-53-48(63)54-30-9-12-39-35(24-30)47(60)62-51(39)40-13-10-31(55)26-44(40)61-45-27-32(56)11-14-41(45)51/h9-14,24,26-27,29,33-34,36-38,42-43,55-58H,4-8,15-23,25,28H2,1-3H3,(H,52,59)(H2,53,54,63)/t29-,33-,34+,36-,37+,38+,42+,43+,49-,50-/m1/s1 MFJKSCWIKMCTMG-RGOSNDNESA-N 50515025 CHEMBL4464514 Oxysterols receptor LXR-beta 7342 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515025&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155530360 440723607 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260575 CC(C)(C)OC(=O)N1Cc2cn[nH]c2C1 InChI=1S/C10H15N3O2/c1-10(2,3)15-9(14)13-5-7-4-11-12-8(7)6-13/h4H,5-6H2,1-3H3,(H,11,12) IBUNCTVDGYIKAP-UHFFFAOYSA-N 50515026 CHEMBL4573961 Oxysterols receptor LXR-beta 225000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515026&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 7147072 440723608 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260576 CC(C)(C)OC(=O)N1CCc2ccc(N)cc2C1 InChI=1S/C14H20N2O2/c1-14(2,3)18-13(17)16-7-6-10-4-5-12(15)8-11(10)9-16/h4-5,8H,6-7,9,15H2,1-3H3 AGRBXKCSGCUXST-UHFFFAOYSA-N 50515027 CHEMBL4522789 Oxysterols receptor LXR-beta 28000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515027&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search BQ3 6JIO 22061016 440723609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260577 Brc1ccc2NC(=O)OCc2c1 InChI=1S/C8H6BrNO2/c9-6-1-2-7-5(3-6)4-12-8(11)10-7/h1-3H,4H2,(H,10,11) SSTOTANBGDRSRF-UHFFFAOYSA-N 50515028 CHEMBL4522284 Oxysterols receptor LXR-beta >500000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515028&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 25918963 440723610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260578 COC(=O)c1ccc2CN(CCn12)C(=O)OC(C)(C)C InChI=1S/C14H20N2O4/c1-14(2,3)20-13(18)15-7-8-16-10(9-15)5-6-11(16)12(17)19-4/h5-6H,7-9H2,1-4H3 COCKREWRKXYGFL-UHFFFAOYSA-N 50515029 CHEMBL4468234 Oxysterols receptor LXR-beta 16000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515029&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 72207455 440723611 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260579 C[C@H](CCC(=O)NCCCCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C51H65N3O8S/c1-29(36-15-16-37-34-28-43(58)42-25-33(57)18-20-50(42,3)38(34)19-21-49(36,37)2)8-17-46(59)52-22-6-4-5-7-23-53-48(63)54-30-9-12-39-35(24-30)47(60)62-51(39)40-13-10-31(55)26-44(40)61-45-27-32(56)11-14-41(45)51/h9-14,24,26-27,29,33-34,36-38,42-43,55-58H,4-8,15-23,25,28H2,1-3H3,(H,52,59)(H2,53,54,63)/t29-,33-,34+,36-,37+,38+,42+,43+,49-,50-/m1/s1 MFJKSCWIKMCTMG-RGOSNDNESA-N 50515025 CHEMBL4464514 Oxysterols receptor LXR-beta 92 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515025&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155530360 440723607 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260580 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 289 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260581 COC(=O)c1ccc2CN(CCn12)C(=O)OC(C)(C)C InChI=1S/C14H20N2O4/c1-14(2,3)20-13(18)15-7-8-16-10(9-15)5-6-11(16)12(17)19-4/h5-6H,7-9H2,1-4H3 COCKREWRKXYGFL-UHFFFAOYSA-N 50515029 CHEMBL4468234 Oxysterols receptor LXR-beta 29000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515029&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 72207455 440723611 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260582 CCOC(=O)c1cn2nc[nH]c(=O)c2c1C(C)C InChI=1S/C12H15N3O3/c1-4-18-12(17)8-5-15-10(9(8)7(2)3)11(16)13-6-14-15/h5-7H,4H2,1-3H3,(H,13,14,16) VTASDCRFXWOYNX-UHFFFAOYSA-N 50515030 CHEMBL4442070 Oxysterols receptor LXR-beta 19000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 135410235 440723612 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260583 Oc1ccc(Cl)cc1 InChI=1S/C6H5ClO/c7-5-1-3-6(8)4-2-5/h1-4,8H WXNZTHHGJRFXKQ-UHFFFAOYSA-N 36299 4-chlorophenol Oxysterols receptor LXR-beta 514000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4CH 3LB3,5M8W,7M0H,7DQW,4DF2,4AWU 4684 172097632 28078 C02124 ZINC00001885 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260584 COc1ccc(OC)c(Cl)c1 InChI=1S/C8H9ClO2/c1-10-6-3-4-8(11-2)7(9)5-6/h3-5H,1-2H3 QMXZSRVFIWACJH-UHFFFAOYSA-N 50515023 CHEMBL4561202 Oxysterols receptor LXR-beta 476000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515023&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 246724 440723605 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260585 CC(C)(C)OC(=O)N1Cc2cn[nH]c2C(C)(C)C1 InChI=1S/C13H21N3O2/c1-12(2,3)18-11(17)16-7-9-6-14-15-10(9)13(4,5)8-16/h6H,7-8H2,1-5H3,(H,14,15) KTJZXUZVDHAVAI-UHFFFAOYSA-N 50515031 CHEMBL4528250 Oxysterols receptor LXR-beta 10000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515031&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 37818370 440723613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260586 CCOC(=O)c1cn2nc[nH]c(=O)c2c1C(C)C InChI=1S/C12H15N3O3/c1-4-18-12(17)8-5-15-10(9(8)7(2)3)11(16)13-6-14-15/h5-7H,4H2,1-3H3,(H,13,14,16) VTASDCRFXWOYNX-UHFFFAOYSA-N 50515030 CHEMBL4442070 Oxysterols receptor LXR-beta 140000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 135410235 440723612 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260587 Oc1ccc(Oc2ccccc2)cc1 InChI=1S/C12H10O2/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9,13H ZSBDGXGICLIJGD-UHFFFAOYSA-N 398051 US10322118, Entry 9 Oxysterols receptor LXR-beta 62000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398051&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search HX8 5Z4O 13254 405268102 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260588 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 2.2 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260589 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 41 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260590 CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C21H27F3N4O4S/c1-13(2)17-10-27(16-5-4-14(11-29)18(8-16)33(3,31)32)6-7-28(17)20-25-9-15(12-30)19(26-20)21(22,23)24/h4-5,8-9,13,17,29-30H,6-7,10-12H2,1-3H3/t17-/m0/s1 FPVIRRAMNBCEDK-KRWDZBQOSA-N 50177015 CHEMBL3814206::US10144715, Compound 19-1 Oxysterols receptor LXR-beta 1.3 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 67S 5I4V 91827457 346549211 CHEMBL3814206 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260591 COC(=O)CC1CC2CC(F)(F)C(C1)N2Cc1ccccc1 InChI=1S/C17H21F2NO2/c1-22-16(21)9-13-7-14-10-17(18,19)15(8-13)20(14)11-12-5-3-2-4-6-12/h2-6,13-15H,7-11H2,1H3 XXNYMPPUQFEXAY-UHFFFAOYSA-N 50515032 CHEMBL4524585 Oxysterols receptor LXR-beta 49000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91800925 440723614 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260592 CCCCOC(=O)c1ccc(O)cc1 InChI=1S/C11H14O3/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7,12H,2-3,8H2,1H3 QFOHBWFCKVYLES-UHFFFAOYSA-N 23448 BUTYLPARABEN::Butyl paraben::Nipabutyl::butyl 4-hydroxybenzoate::cid_7184 Oxysterols receptor LXR-beta 66000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23448&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 27K 4MG9,5Z9E,7DTS 7184 50091711 ZINC01586769 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260593 Oc1cccc(Cl)c1 InChI=1S/C6H5ClO/c7-5-2-1-3-6(8)4-5/h1-4,8H HORNXRXVQWOLPJ-UHFFFAOYSA-N 50167952 3-chlorophenol::CHEMBL41172 Oxysterols receptor LXR-beta 184000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167952&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3CH 1LI3,5KBH,5M8Y 7933 104053131 52879 CHEMBL41172 DB01957 C14270 ZINC00404329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260594 CCOC(=O)c1ccc(CN(Cc2ccc(cc2)-c2cccc(c2)S(C)(=O)=O)S(=O)(=O)c2c(C)cc(C)cc2C)o1 InChI=1S/C31H33NO7S2/c1-6-38-31(33)29-15-14-27(39-29)20-32(41(36,37)30-22(3)16-21(2)17-23(30)4)19-24-10-12-25(13-11-24)26-8-7-9-28(18-26)40(5,34)35/h7-18H,6,19-20H2,1-5H3 HDZWHJYZJWLTAG-UHFFFAOYSA-N 50465712 CHEMBL4284414 Oxysterols receptor LXR-beta 352 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465712&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71478195 433932977 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260595 COC(=O)CC1CC2CC(F)(F)C(C1)N2Cc1ccccc1 InChI=1S/C17H21F2NO2/c1-22-16(21)9-13-7-14-10-17(18,19)15(8-13)20(14)11-12-5-3-2-4-6-12/h2-6,13-15H,7-11H2,1H3 XXNYMPPUQFEXAY-UHFFFAOYSA-N 50515032 CHEMBL4524585 Oxysterols receptor LXR-beta 18000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91800925 440723614 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260596 Oc1ccc(Sc2ccc(O)cc2)cc1 InChI=1S/C12H10O2S/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8,13-14H VWGKEVWFBOUAND-UHFFFAOYSA-N 50515033 CHEBI:38957::CHEMBL3183502 Oxysterols receptor LXR-beta 68000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515033&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search A8K 5Z4H,5OS5 17570 440723615 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260597 CC(C)(C)OC(=O)N1CCc2ccc(N)cc2C1 InChI=1S/C14H20N2O2/c1-14(2,3)18-13(17)16-7-6-10-4-5-12(15)8-11(10)9-16/h4-5,8H,6-7,9,15H2,1-3H3 AGRBXKCSGCUXST-UHFFFAOYSA-N 50515027 CHEMBL4522789 Oxysterols receptor LXR-beta 57000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515027&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search BQ3 6JIO 22061016 440723609 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260598 Oc1cccc(Cl)c1 InChI=1S/C6H5ClO/c7-5-2-1-3-6(8)4-5/h1-4,8H HORNXRXVQWOLPJ-UHFFFAOYSA-N 50167952 3-chlorophenol::CHEMBL41172 Oxysterols receptor LXR-beta 519000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167952&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 3CH 1LI3,5KBH,5M8Y 7933 104053131 52879 CHEMBL41172 DB01957 C14270 ZINC00404329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260599 Brc1nn(C2CCCCO2)c2ncccc12 InChI=1S/C11H12BrN3O/c12-10-8-4-3-6-13-11(8)15(14-10)9-5-1-2-7-16-9/h3-4,6,9H,1-2,5,7H2 SWWVASLRSRLYJD-UHFFFAOYSA-N 50515034 CHEMBL4456484 Oxysterols receptor LXR-beta 209000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515034&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 91663938 440723616 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260600 Oc1ccc(Oc2ccccc2)cc1 InChI=1S/C12H10O2/c13-10-6-8-12(9-7-10)14-11-4-2-1-3-5-11/h1-9,13H ZSBDGXGICLIJGD-UHFFFAOYSA-N 398051 US10322118, Entry 9 Oxysterols receptor LXR-beta 593000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=398051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=398051&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search HX8 5Z4O 13254 405268102 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260601 N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12 InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1 HFNKQEVNSGCOJV-OAHLLOKOSA-N 50355501 INCB-018424::RUXOLITINIB::RUXOLITINIB PHOSPHATE::US10112907, Example 00016::US10766894, Compound TABLE 1.1::US10875847, Compound JAKAFI::US11203595, TABLE 1.1::US11279703, TABLE 6.147 Oxysterols receptor LXR-beta 45000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355501&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search RXT 6VNK,6WTN,6VGL,4U5J,7F3G 25126798 136959525 66919 DB08877 ZINC43207851 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260602 CC(C)(C)OC(=O)N1CC2CC(CO)CC2C1 InChI=1S/C13H23NO3/c1-13(2,3)17-12(16)14-6-10-4-9(8-15)5-11(10)7-14/h9-11,15H,4-8H2,1-3H3 XRNJMGKDWQLIJX-UHFFFAOYSA-N 50515035 CHEMBL4558077 Oxysterols receptor LXR-beta 35000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515035&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 68469431 440723617 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260603 CC(C)[C@@H]1CN(CCN1c1ncc(COC(=O)CCCCCNC(=S)Nc2ccc3c(c2)C(=O)OC32c3ccc(O)cc3Oc3cc(O)ccc23)c(n1)C(F)(F)F)c1ccc(CO)c(c1)S(C)(=O)=O InChI=1S/C48H49F3N6O10S2/c1-27(2)38-24-56(31-10-8-28(25-58)41(20-31)69(3,63)64)17-18-57(38)45-53-23-29(43(55-45)48(49,50)51)26-65-42(61)7-5-4-6-16-52-46(68)54-30-9-13-35-34(19-30)44(62)67-47(35)36-14-11-32(59)21-39(36)66-40-22-33(60)12-15-37(40)47/h8-15,19-23,27,38,58-60H,4-7,16-18,24-26H2,1-3H3,(H2,52,54,68)/t38-/m0/s1 XWKXPLRWESMPNJ-LHEWISCISA-N 50515036 CHEMBL4584267 Oxysterols receptor LXR-beta 49 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515036&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155566145 440723618 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260604 Oc1ccc(Cl)cc1 InChI=1S/C6H5ClO/c7-5-1-3-6(8)4-2-5/h1-4,8H WXNZTHHGJRFXKQ-UHFFFAOYSA-N 36299 4-chlorophenol Oxysterols receptor LXR-beta 169000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4CH 3LB3,5M8W,7M0H,7DQW,4DF2,4AWU 4684 172097632 28078 C02124 ZINC00001885 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260605 COC(=O)c1ccc2cc[nH]c2c1 InChI=1S/C10H9NO2/c1-13-10(12)8-3-2-7-4-5-11-9(7)6-8/h2-6,11H,1H3 AYYOZKHMSABVRP-UHFFFAOYSA-N 93021 Indole-6-carboxylate::Indole-7-carboxylate Oxysterols receptor LXR-beta 302000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=93021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=93021&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 639844 163340156 ZINC02558204 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260606 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta 14 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51260607 CC(C)(C)OC(=O)N1Cc2cn[nH]c2C(C)(C)C1 InChI=1S/C13H21N3O2/c1-12(2,3)18-11(17)16-7-9-6-14-15-10(9)13(4,5)8-16/h6H,7-8H2,1-5H3,(H,14,15) KTJZXUZVDHAVAI-UHFFFAOYSA-N 50515031 CHEMBL4528250 Oxysterols receptor LXR-beta 19000 ChEMBL 10.1016/j.ejmech.2019.06.011 10.7270/Q2BC42WH 31202993 Zhang, Z; Chen, H; Chen, Z; Ding, P; Ju, Y; Gu, Q; Xu, J; Zhou, H Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50515031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50515031&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 37818370 440723613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244366 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1COc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H25F8NO6S/c29-18-6-8-19(9-7-18)44(41,42)25-11-12-37(23(38)15-1-3-16(4-2-15)24(39)40)22(25)14-43-21-13-17(5-10-20(21)25)26(30,27(31,32)33)28(34,35)36/h5-10,13,15-16,22H,1-4,11-12,14H2,(H,39,40)/t15-,16-,22-,25-/m1/s1 USEIONJENDBBQE-KBLCWGLDSA-N 50509331 CHEMBL4527625 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509331&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155544387 440717916 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244368 Cc1ccc(cc1)S(=O)(=O)[C@@]12CCN([C@@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C30H30F7NO5S/c1-17-2-10-22(11-3-17)44(42,43)27-14-15-38(25(39)18-4-6-19(7-5-18)26(40)41)24(27)13-8-20-16-21(9-12-23(20)27)28(31,29(32,33)34)30(35,36)37/h2-3,9-12,16,18-19,24H,4-8,13-15H2,1H3,(H,40,41)/t18-,19-,24-,27-/m1/s1 JDFDTUYICUVLET-FGXABTBTSA-N 50509332 CHEMBL4462790 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509332&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 148034311 440717917 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244369 OC(=O)[C@H]1CC[C@@](F)(CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H26F9NO5S/c30-19-3-5-20(6-4-19)45(43,44)26-13-14-39(24(42)25(31)11-9-16(10-12-25)23(40)41)22(26)8-1-17-15-18(2-7-21(17)26)27(32,28(33,34)35)29(36,37)38/h2-7,15-16,22H,1,8-14H2,(H,40,41)/t16-,22-,25+,26-/m1/s1 IXBCMUKVFIGIKH-PNOGGZOTSA-N 382181 (1S,4s)-4-fluoro-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)cyclohexane-1-carboxylic acid and (1S,4s)-1-fluoro-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)cyclohexane-1-carboxylic acid::US10273259, Example 3 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382181&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122669173 404851554 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244422 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H27F8NO5S/c30-20-7-9-21(10-8-20)44(42,43)26-13-14-38(24(39)16-1-3-17(4-2-16)25(40)41)23(26)12-5-18-15-19(6-11-22(18)26)27(31,28(32,33)34)29(35,36)37/h6-11,15-17,23H,1-5,12-14H2,(H,40,41)/t16-,17-,23-,26-/m1/s1 FEJZVGPREBSBIT-NIULTJEISA-N 382173 (1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)cyclohexane-1-carboxylic acid::US10273259, Example 1::US10711020, Example 1 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382173&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O5B 6U25 122669106 404851546 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244423 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1cccc(Cl)c1 InChI=1S/C29H27ClF7NO5S/c30-20-2-1-3-21(15-20)44(42,43)26-12-13-38(24(39)16-4-6-17(7-5-16)25(40)41)23(26)11-8-18-14-19(9-10-22(18)26)27(31,28(32,33)34)29(35,36)37/h1-3,9-10,14-17,23H,4-8,11-13H2,(H,40,41)/t16-,17-,23-,26-/m1/s1 CFTRQLKAHBITQD-NIULTJEISA-N 50509340 CHEMBL4475601 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509340&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155537856 440717925 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244424 Cc1cccc(c1)S(=O)(=O)[C@@]12CCN([C@@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C30H30F7NO5S/c1-17-3-2-4-22(15-17)44(42,43)27-13-14-38(25(39)18-5-7-19(8-6-18)26(40)41)24(27)12-9-20-16-21(10-11-23(20)27)28(31,29(32,33)34)30(35,36)37/h2-4,10-11,15-16,18-19,24H,5-9,12-14H2,1H3,(H,40,41)/t18-,19-,24-,27-/m1/s1 UCLOLQONKUCIPI-FGXABTBTSA-N 50509336 CHEMBL4458283 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509336&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155526989 440717921 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244425 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C29H28F7NO5S/c30-27(28(31,32)33,29(34,35)36)20-11-12-22-19(16-20)10-13-23-26(22,43(41,42)21-4-2-1-3-5-21)14-15-37(23)24(38)17-6-8-18(9-7-17)25(39)40/h1-5,11-12,16-18,23H,6-10,13-15H2,(H,39,40)/t17-,18-,23-,26-/m1/s1 SXKKMGOPECZXNY-JJMBJGOUSA-N 382280 US10273259, Example 49::US10711020, Example 49 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382280&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122678983 404851653 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244426 OC(=O)[C@H]1CC[C@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H27F8NO5S/c30-20-7-9-21(10-8-20)44(42,43)26-13-14-38(24(39)16-1-3-17(4-2-16)25(40)41)23(26)12-5-18-15-19(6-11-22(18)26)27(31,28(32,33)34)29(35,36)37/h6-11,15-17,23H,1-5,12-14H2,(H,40,41)/t16-,17+,23-,26-/m1/s1 FEJZVGPREBSBIT-UCHKMINESA-N 50509341 CHEMBL4465091 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509341&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122669106 440717926 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244427 OC(=O)C12CC(C1)(C2)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H23F8NO5S/c29-17-3-5-18(6-4-17)43(41,42)25-9-10-37(21(38)23-12-24(13-23,14-23)22(39)40)20(25)8-1-15-11-16(2-7-19(15)25)26(30,27(31,32)33)28(34,35)36/h2-7,11,20H,1,8-10,12-14H2,(H,39,40)/t20-,23?,24?,25-/m1/s1 VCOSISKXMJHFPP-ZSAXZHEQSA-N 382702 US10273259, Example 411::US10711020, Example 411 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382702&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122679031 404852050 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244428 C[C@@]1(CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(O)=O InChI=1S/C30H29F8NO5S/c1-26(25(41)42)12-10-17(11-13-26)24(40)39-15-14-27(45(43,44)21-6-4-20(31)5-7-21)22-8-3-19(16-18(22)2-9-23(27)39)28(32,29(33,34)35)30(36,37)38/h3-8,16-17,23H,2,9-15H2,1H3,(H,41,42)/t17-,23-,26-,27-/m1/s1 RNUYUEWIROQCAN-ZKPUSUNFSA-N 382355 US10273259, Example 68::US10711020, Example 68 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382355&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122678779 404851727 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244429 CC(=O)N1CCC(CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H28F8N2O4S/c1-17(40)38-13-10-18(11-14-38)25(41)39-15-12-26(44(42,43)22-6-4-21(30)5-7-22)23-8-3-20(16-19(23)2-9-24(26)39)27(31,28(32,33)34)29(35,36)37/h3-8,16,18,24H,2,9-15H2,1H3/t24-,26-/m1/s1 KRFUPWONDXEJMB-AOYPEHQESA-N 382201 US10273259, Example 13::US10711020, Example 13 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382201&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122678748 404851574 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244430 Fc1ccc(cc1)S(=O)(=O)[C@@]12CCN([C@@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)C(=O)C1CCS(=O)(=O)CC1 InChI=1S/C27H25F8NO5S2/c28-19-3-5-20(6-4-19)43(40,41)24-11-12-36(23(37)16-9-13-42(38,39)14-10-16)22(24)8-1-17-15-18(2-7-21(17)24)25(29,26(30,31)32)27(33,34)35/h2-7,15-16,22H,1,8-14H2/t22-,24-/m1/s1 KJYXXEYJECOAQK-ISKFKSNPSA-N 382195 US10273259, Example 11::US10711020, Example 11 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382195&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122678562 404851568 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244431 CN1C[C@H]2N(CC[C@]2(c2ccc(cc12)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C29H28F8N2O5S/c1-38-15-23-26(45(43,44)20-9-7-19(30)8-10-20,12-13-39(23)24(40)16-2-4-17(5-3-16)25(41)42)21-11-6-18(14-22(21)38)27(31,28(32,33)34)29(35,36)37/h6-11,14,16-17,23H,2-5,12-13,15H2,1H3,(H,41,42)/t16-,17-,23-,26-/m1/s1 JDAJQYNRMPEXFU-NIULTJEISA-N 50509335 CHEMBL4579028 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509335&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155565257 440717920 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244432 CCN1C[C@H]2N(CC[C@]2(c2ccc(cc12)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C30H30F8N2O5S/c1-2-39-16-24-27(46(44,45)21-10-8-20(31)9-11-21,13-14-40(24)25(41)17-3-5-18(6-4-17)26(42)43)22-12-7-19(15-23(22)39)28(32,29(33,34)35)30(36,37)38/h7-12,15,17-18,24H,2-6,13-14,16H2,1H3,(H,42,43)/t17-,18-,24-,27-/m1/s1 NXUBBEJNBJAHRO-BKNJMBQISA-N 50509339 CHEMBL4527982 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509339&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155544524 440717924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244433 CCCN1C[C@H]2N(CC[C@]2(c2ccc(cc12)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O InChI=1S/C31H32F8N2O5S/c1-2-14-40-17-25-28(47(45,46)22-10-8-21(32)9-11-22,13-15-41(25)26(42)18-3-5-19(6-4-18)27(43)44)23-12-7-20(16-24(23)40)29(33,30(34,35)36)31(37,38)39/h7-12,16,18-19,25H,2-6,13-15,17H2,1H3,(H,43,44)/t18-,19-,25-,28-/m1/s1 BTJFMVNGAMYMNQ-IBBOJXSKSA-N 50509338 CHEMBL4457990 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509338&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155525669 440717923 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244434 CN1C[C@H]2N(CC[C@]2(c2ccc(cc12)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(=O)C1(O)CCS(=O)(=O)CC1 InChI=1S/C27H26F8N2O6S2/c1-36-15-21-24(45(42,43)18-5-3-17(28)4-6-18,8-11-37(21)22(38)23(39)9-12-44(40,41)13-10-23)19-7-2-16(14-20(19)36)25(29,26(30,31)32)27(33,34)35/h2-7,14,21,39H,8-13,15H2,1H3/t21-,24-/m1/s1 LWIUACLWPFXZHB-ZJSXRUAMSA-N 50509333 CHEMBL4566371 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155560819 440717918 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244438 OC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H25F8NO6S2/c28-18-3-5-19(6-4-18)44(41,42)24-9-12-36(22(37)23(38)10-13-43(39,40)14-11-23)21(24)8-1-16-15-17(2-7-20(16)24)25(29,26(30,31)32)27(33,34)35/h2-7,15,21,38H,1,8-14H2/t21-,24-/m1/s1 ONXFNBOZJKXCNC-ZJSXRUAMSA-N 382356 US10273259, Example 69::US10711020, Example 69 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382356&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122669265 404851728 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244487 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1 InChI=1S/C29H27ClF7NO5S/c30-20-7-9-21(10-8-20)44(42,43)26-13-14-38(24(39)16-1-3-17(4-2-16)25(40)41)23(26)12-5-18-15-19(6-11-22(18)26)27(31,28(32,33)34)29(35,36)37/h6-11,15-17,23H,1-5,12-14H2,(H,40,41)/t16-,17-,23-,26-/m1/s1 ASSZTGFDWPKORU-NIULTJEISA-N 50509330 CHEMBL4525527 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509330&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155543172 440717915 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244488 OC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H25F8NO6S2/c28-18-3-5-19(6-4-18)44(41,42)24-9-12-36(22(37)23(38)10-13-43(39,40)14-11-23)21(24)8-1-16-15-17(2-7-20(16)24)25(29,26(30,31)32)27(33,34)35/h2-7,15,21,38H,1,8-14H2/t21-,24-/m1/s1 ONXFNBOZJKXCNC-ZJSXRUAMSA-N 382356 US10273259, Example 69::US10711020, Example 69 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382356&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122669265 404851728 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244489 OC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@@]2([C@H]1CNc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H24F8N2O6S2/c27-16-2-4-17(5-3-16)44(41,42)23-7-10-36(21(37)22(38)8-11-43(39,40)12-9-22)20(23)14-35-19-13-15(1-6-18(19)23)24(28,25(29,30)31)26(32,33)34/h1-6,13,20,35,38H,7-12,14H2/t20-,23-/m1/s1 JVTKTQZHQLEDDU-NFBKMPQASA-N 50509334 CHEMBL4436417 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509334&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155511797 440717919 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244515 C[C@@]1(CC[C@@H](CC1)C(O)=O)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C30H29F8NO5S/c1-26(12-10-17(11-13-26)24(40)41)25(42)39-15-14-27(45(43,44)21-6-4-20(31)5-7-21)22-8-3-19(16-18(22)2-9-23(27)39)28(32,29(33,34)35)30(36,37)38/h3-8,16-17,23H,2,9-15H2,1H3,(H,40,41)/t17-,23-,26-,27-/m1/s1 IFTFEJQRBOPQKV-ZKPUSUNFSA-N 382353 US10273259, Example 66::US10711020, Example 66 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382353&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122669103 404851725 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244538 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1cccc(F)c1 InChI=1S/C29H27F8NO5S/c30-20-2-1-3-21(15-20)44(42,43)26-12-13-38(24(39)16-4-6-17(7-5-16)25(40)41)23(26)11-8-18-14-19(9-10-22(18)26)27(31,28(32,33)34)29(35,36)37/h1-3,9-10,14-17,23H,4-8,11-13H2,(H,40,41)/t16-,17-,23-,26-/m1/s1 LIWMGZMUBKUREU-NIULTJEISA-N 50509337 CHEMBL4555822 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509337&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155556708 440717922 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244539 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)Cc1ccccc1 InChI=1S/C30H30F7NO5S/c31-28(29(32,33)34,30(35,36)37)22-11-12-23-21(16-22)10-13-24-27(23,44(42,43)17-18-4-2-1-3-5-18)14-15-38(24)25(39)19-6-8-20(9-7-19)26(40)41/h1-5,11-12,16,19-20,24H,6-10,13-15,17H2,(H,40,41)/t19-,20-,24-,27-/m1/s1 RTRLDILTCFOVAH-URNDPJOWSA-N 50509328 CHEMBL4452650 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509328&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155522788 440717913 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244540 OC(=O)[C@H]1CC[C@@](O)(CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H27F8NO6S/c30-19-3-5-20(6-4-19)45(43,44)26-13-14-38(24(41)25(42)11-9-16(10-12-25)23(39)40)22(26)8-1-17-15-18(2-7-21(17)26)27(31,28(32,33)34)29(35,36)37/h2-7,15-16,22,42H,1,8-14H2,(H,39,40)/t16-,22-,25+,26-/m1/s1 NIKFOKKZAYXJKS-PNOGGZOTSA-N 382357 US10273259, Example 70::US10711020, Example 70 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382357&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122678576 404851729 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244541 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@@]2([C@H]1CNc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H26F8N2O5S/c29-18-6-8-19(9-7-18)44(42,43)25-11-12-38(23(39)15-1-3-16(4-2-15)24(40)41)22(25)14-37-21-13-17(5-10-20(21)25)26(30,27(31,32)33)28(34,35)36/h5-10,13,15-16,22,37H,1-4,11-12,14H2,(H,40,41)/t15-,16-,22-,25-/m1/s1 WCICLOUJTXBWJG-KBLCWGLDSA-N 50509327 CHEMBL4464711 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509327&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155530678 440717912 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244542 OC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@@]2([C@H]1COc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H23F8NO7S2/c27-16-2-4-17(5-3-16)44(40,41)23-7-10-35(21(36)22(37)8-11-43(38,39)12-9-22)20(23)14-42-19-13-15(1-6-18(19)23)24(28,25(29,30)31)26(32,33)34/h1-6,13,20,37H,7-12,14H2/t20-,23-/m1/s1 KIQQPHOZVGKIIP-NFBKMPQASA-N 50509329 CHEMBL4578712 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509329&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155564933 440717914 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51244550 OC(=O)C12CCC(CC1)(CC2)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C31H29F8NO5S/c32-20-3-5-21(6-4-20)46(44,45)28-15-16-40(24(41)26-9-12-27(13-10-26,14-11-26)25(42)43)23(28)8-1-18-17-19(2-7-22(18)28)29(33,30(34,35)36)31(37,38)39/h2-7,17,23H,1,8-16H2,(H,42,43)/t23-,26?,27?,28-/m1/s1 FLJYXIWKPNZXTJ-LJJHVHFXSA-N 382198 US10273259, Example 12::US10711020, Example 12 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acs.jmedchem.9b01369 10.7270/Q2G44TKD 31638797 Marcoux, D; Duan, JJ; Shi, Q; Cherney, RJ; Srivastava, AS; Cornelius, L; Batt, DG; Liu, Q; Beaudoin-Bertrand, M; Weigelt, CA; Khandelwal, P; Vishwakrishnan, S; Selvakumar, K; Karmakar, A; Gupta, AK; Basha, M; Ramlingam, S; Manjunath, N; Vanteru, S; Karmakar, S; Maddala, N; Vetrichelvan, M; Gupta, A; Rampulla, RA; Mathur, A; Yip, S; Li, P; Wu, DR; Khan, J; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Cvijic, ME; Li, S; Shuster, DJ; Borowski, V; Xie, JH; McIntyre, KW; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Hynes, J; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=382198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=382198&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 122678563 404851571 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246418 COC(=O)N1CCC(C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C21H18F7NO5S/c1-34-17(30)29-11-10-18(12-29,35(32,33)16-8-6-15(22)7-9-16)13-2-4-14(5-3-13)19(31,20(23,24)25)21(26,27)28/h2-9,31H,10-12H2,1H3 OJBNWWGQLDOQLL-UHFFFAOYSA-N 253102 US9458171, 62 Oxysterols receptor LXR-beta 1900 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253102&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217561 346547470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246419 CC(=O)N1CCC(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H26F8N2O4S/c1-17(38)36-13-10-18(11-14-36)23(39)37-15-12-24(16-37,42(40,41)22-8-6-21(28)7-9-22)19-2-4-20(5-3-19)25(29,26(30,31)32)27(33,34)35/h2-9,18H,10-16H2,1H3/t24-/m0/s1 ZCVYLZVBYDUMQY-DEOSSOPVSA-N 253144 US9458171, 104 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253144&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217596 346547509 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246420 COc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C28H28F7NO6S/c1-42-21-10-12-22(13-11-21)43(40,41)25(14-15-36(16-25)23(37)17-2-4-18(5-3-17)24(38)39)19-6-8-20(9-7-19)26(29,27(30,31)32)28(33,34)35/h6-13,17-18H,2-5,14-16H2,1H3,(H,38,39)/t17-,18-,25-/m0/s1 PHWSECSLTQRKEH-RPPIVITFSA-N 253137 US9458171, 97 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253137&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217593 346547504 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246466 OC(c1ccc(cc1)[C@@]1(CCNC1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C19H16F7NO3S/c20-14-5-7-15(8-6-14)31(29,30)16(9-10-27-11-16)12-1-3-13(4-2-12)17(28,18(21,22)23)19(24,25)26/h1-8,27-28H,9-11H2/t16-/m0/s1 OMYNIZMYRGKJIF-INIZCTEOSA-N 253047 US9458171, 3 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253047&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208079 346547415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246467 CCNC(=O)N1CCC(C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C22H21F7N2O4S/c1-2-30-18(32)31-12-11-19(13-31,36(34,35)17-9-7-16(23)8-10-17)14-3-5-15(6-4-14)20(33,21(24,25)26)22(27,28)29/h3-10,33H,2,11-13H2,1H3,(H,30,32) MBZXEXLFJWPIQL-UHFFFAOYSA-N 253111 US9458171, 71 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253111&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217576 346547479 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246468 CC(=O)N1CCC(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H27F7N2O5S/c1-17(37)35-13-10-18(11-14-35)23(38)36-15-12-24(16-36,42(40,41)22-8-6-21(28)7-9-22)19-2-4-20(5-3-19)25(39,26(29,30)31)27(32,33)34/h2-9,18,39H,10-16H2,1H3/t24-/m0/s1 KJQFBTHRWLTPCF-DEOSSOPVSA-N 253054 US9458171, 11 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253054&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208112 346547422 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246469 CS(=O)(=O)N1CCC(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H27F7N2O6S2/c1-42(38,39)35-13-10-17(11-14-35)22(36)34-15-12-23(16-34,43(40,41)21-8-6-20(27)7-9-21)18-2-4-19(5-3-18)24(37,25(28,29)30)26(31,32)33/h2-9,17,37H,10-16H2,1H3/t23-/m0/s1 QVPVWDKIJLWWPO-QHCPKHFHSA-N 253096 US9458171, 56 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253096&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217555 346547464 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246470 CC(=O)N1CCN(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H26F7N3O5S/c1-17(37)34-12-14-35(15-13-34)22(38)36-11-10-23(16-36,42(40,41)21-8-6-20(27)7-9-21)18-2-4-19(5-3-18)24(39,25(28,29)30)26(31,32)33/h2-9,39H,10-16H2,1H3/t23-/m0/s1 LGFLFKROQCMBLV-QHCPKHFHSA-N 253055 US9458171, 12 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253055&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search L8A 6O98 118207970 346547423 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246471 CC(=O)N1CCN(CC1)C(=O)N1CC[C@@](C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H26F7N3O5S/c1-17(37)34-12-14-35(15-13-34)22(38)36-11-10-23(16-36,42(40,41)21-8-6-20(27)7-9-21)18-2-4-19(5-3-18)24(39,25(28,29)30)26(31,32)33/h2-9,39H,10-16H2,1H3/t23-/m1/s1 LGFLFKROQCMBLV-HSZRJFAPSA-N 253119 US9458171, 79 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253119&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217580 346547487 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246472 CS(=O)(=O)N1CCC(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H26F8N2O5S2/c1-42(38,39)36-13-10-17(11-14-36)22(37)35-15-12-23(16-35,43(40,41)21-8-6-20(27)7-9-21)18-2-4-19(5-3-18)24(28,25(29,30)31)26(32,33)34/h2-9,17H,10-16H2,1H3/t23-/m0/s1 WHXSTZQJSMXRER-QHCPKHFHSA-N 253546 US9458171, 506 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253546&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217927 346547910 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246473 OC(=O)[C@H]1CC[C@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H25F8NO5S/c28-20-9-11-21(12-10-20)42(40,41)24(13-14-36(15-24)22(37)16-1-3-17(4-2-16)23(38)39)18-5-7-19(8-6-18)25(29,26(30,31)32)27(33,34)35/h5-12,16-17H,1-4,13-15H2,(H,38,39)/t16-,17+,24-/m0/s1 AVHWMAVUUHFRKE-SRGWNRLKSA-N 253138 US9458171, 100::US9458171, 98::US9458171, 99 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253138&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208018 346547505 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246474 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C27H26F7NO5S/c28-25(26(29,30)31,27(32,33)34)20-12-10-19(11-13-20)24(41(39,40)21-4-2-1-3-5-21)14-15-35(16-24)22(36)17-6-8-18(9-7-17)23(37)38/h1-5,10-13,17-18H,6-9,14-16H2,(H,37,38)/t17-,18-,24-/m0/s1 YFUAPIFVWFDXKT-XFAGBWLFSA-N 50509879 CHEMBL4527202 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509879&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155544796 440718464 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246475 Cc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C28H28F7NO5S/c1-17-2-12-22(13-3-17)42(40,41)25(14-15-36(16-25)23(37)18-4-6-19(7-5-18)24(38)39)20-8-10-21(11-9-20)26(29,27(30,31)32)28(33,34)35/h2-3,8-13,18-19H,4-7,14-16H2,1H3,(H,38,39)/t18-,19-,25-/m0/s1 PSNZDXCQJULFRM-MHPIHPPYSA-N 253457 US9458171, 417 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253457&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208086 346547821 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246476 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1 InChI=1S/C27H25ClF7NO5S/c28-20-9-11-21(12-10-20)42(40,41)24(13-14-36(15-24)22(37)16-1-3-17(4-2-16)23(38)39)18-5-7-19(8-6-18)25(29,26(30,31)32)27(33,34)35/h5-12,16-17H,1-4,13-15H2,(H,38,39)/t16-,17-,24-/m0/s1 OWEBVLUQSSGDRX-UAVUOLJFSA-N 253455 US9458171, 415 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253455&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208026 346547819 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246477 Cc1cc(ccc1F)S(=O)(=O)[C@]1(CCN(C1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C28H27F8NO5S/c1-16-14-21(10-11-22(16)29)43(41,42)25(12-13-37(15-25)23(38)17-2-4-18(5-3-17)24(39)40)19-6-8-20(9-7-19)26(30,27(31,32)33)28(34,35)36/h6-11,14,17-18H,2-5,12-13,15H2,1H3,(H,39,40)/t17-,18-,25-/m0/s1 FOMZHKMHJLHIQZ-RPPIVITFSA-N 253157 US9458171, 117 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253157&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217609 346547522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246492 CC(=O)N1CCC(C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C21H18F7NO4S/c1-13(30)29-11-10-18(12-29,34(32,33)17-8-6-16(22)7-9-17)14-2-4-15(5-3-14)19(31,20(23,24)25)21(26,27)28/h2-9,31H,10-12H2,1H3 WSIFDSOTEVLMPK-UHFFFAOYSA-N 253088 US9458171, 48 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253088&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217550 346547456 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246493 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H26F7NO6S/c28-20-9-11-21(12-10-20)42(40,41)24(13-14-35(15-24)22(36)16-1-3-17(4-2-16)23(37)38)18-5-7-19(8-6-18)25(39,26(29,30)31)27(32,33)34/h5-12,16-17,39H,1-4,13-15H2,(H,37,38)/t16-,17-,24-/m0/s1 JROYPKLSTOFQSI-UAVUOLJFSA-N 253059 US9458171, 16 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253059&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118207854 346547427 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246494 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)c(c1)C1CC1 InChI=1S/C30H29F8NO5S/c31-24-12-11-22(15-23(24)17-1-2-17)45(43,44)27(13-14-39(16-27)25(40)18-3-5-19(6-4-18)26(41)42)20-7-9-21(10-8-20)28(32,29(33,34)35)30(36,37)38/h7-12,15,17-19H,1-6,13-14,16H2,(H,41,42)/t18-,19-,27-/m0/s1 LWEFWPKVZAGQGI-BATDWUPUSA-N 253160 US9458171, 120 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253160&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217612 346547525 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246503 CC(=O)N1CCN(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H25F8N3O4S/c1-17(38)35-12-14-36(15-13-35)22(39)37-11-10-23(16-37,42(40,41)21-8-6-20(27)7-9-21)18-2-4-19(5-3-18)24(28,25(29,30)31)26(32,33)34/h2-9H,10-16H2,1H3/t23-/m0/s1 AENFRJUKGBLCPJ-QHCPKHFHSA-N 253156 US9458171, 116 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253156&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217608 346547521 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246522 OC(c1ccc(cc1)C1(CCN(C1)C(=O)C1CCCC1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C25H24F7NO4S/c26-19-9-11-20(12-10-19)38(36,37)22(13-14-33(15-22)21(34)16-3-1-2-4-16)17-5-7-18(8-6-17)23(35,24(27,28)29)25(30,31)32/h5-12,16,35H,1-4,13-15H2 AWOZLZVEQAYRHZ-UHFFFAOYSA-N 253090 US9458171, 50 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253090&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217548 346547458 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246523 OC(c1ccc(cc1)[C@]1(CCNC1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F InChI=1S/C19H16F7NO3S/c20-14-5-7-15(8-6-14)31(29,30)16(9-10-27-11-16)12-1-3-13(4-2-12)17(28,18(21,22)23)19(24,25)26/h1-8,27-28H,9-11H2/t16-/m1/s1 OMYNIZMYRGKJIF-MRXNPFEDSA-N 253048 US9458171, 4 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253048&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208092 346547416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246524 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H25F8NO5S/c28-20-9-11-21(12-10-20)42(40,41)24(13-14-36(15-24)22(37)16-1-3-17(4-2-16)23(38)39)18-5-7-19(8-6-18)25(29,26(30,31)32)27(33,34)35/h5-12,16-17H,1-4,13-15H2,(H,38,39)/t16-,17-,24-/m0/s1 AVHWMAVUUHFRKE-UAVUOLJFSA-N 253135 US9458171, 95 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253135&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O5A 6P9F 118208018 346547502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246525 CCc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C29H30F7NO5S/c1-2-18-3-13-23(14-4-18)43(41,42)26(15-16-37(17-26)24(38)19-5-7-20(8-6-19)25(39)40)21-9-11-22(12-10-21)27(30,28(31,32)33)29(34,35)36/h3-4,9-14,19-20H,2,5-8,15-17H2,1H3,(H,39,40)/t19-,20-,26-/m0/s1 LABVKPUHHCCTTJ-DYLHXGEVSA-N 253462 US9458171, 422 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253462&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217875 346547826 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246526 CCc1cc(ccc1F)S(=O)(=O)[C@]1(CCN(C1)C(=O)[C@H]1CC[C@@H](CC1)C(O)=O)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C29H29F8NO5S/c1-2-17-15-22(11-12-23(17)30)44(42,43)26(13-14-38(16-26)24(39)18-3-5-19(6-4-18)25(40)41)20-7-9-21(10-8-20)27(31,28(32,33)34)29(35,36)37/h7-12,15,18-19H,2-6,13-14,16H2,1H3,(H,40,41)/t18-,19-,26-/m0/s1 IMASCFKPOMBBQD-DGUDUIIESA-N 253159 US9458171, 119 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253159&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217611 346547524 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51246529 OC(=O)C1CCN(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H24F8N2O5S/c27-19-5-7-20(8-6-19)42(40,41)23(11-14-36(15-23)22(39)35-12-9-16(10-13-35)21(37)38)17-1-3-18(4-2-17)24(28,25(29,30)31)26(32,33)34/h1-8,16H,9-15H2,(H,37,38)/t23-/m0/s1 ZJXNCGWVVZRDGK-QHCPKHFHSA-N 253551 US9458171, 511 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.9b00010 10.7270/Q2T72MS0 30891142 Duan, JJ; Lu, Z; Jiang, B; Stachura, S; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; Galella, MA; Wu, DR; Yarde, M; Shen, DR; Shuster, DJ; Borowski, V; Xie, JH; Zhang, L; Vanteru, S; Gupta, AK; Mathur, A; Zhao, Q; Foster, W; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253551&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217932 346547915 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 914103 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 40.0 US Patent 10.7270/Q2V127W1 aid1804493 US10669296 Martinez, EJ; Kaiser, B; Tavazoie, SF; Kurth, I; Gonsalves, FC; Darst, Jr., DM; Tavazoie, MF Rgenix, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 914105 CC(CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F InChI=1S/C34H33ClF3NO3/c1-24(18-19-42-29-16-8-10-25(20-29)21-32(40)41)39(22-28-15-9-17-31(33(28)35)34(36,37)38)23-30(26-11-4-2-5-12-26)27-13-6-3-7-14-27/h2-17,20,24,30H,18-19,21-23H2,1H3,(H,40,41) ZLJZDYOBXVOTSA-UHFFFAOYSA-N 426493 US10543183, Compound SB742881::US10669296, Compound SB742881::US10945978, Compound 25 Oxysterols receptor LXR-beta 25.0 US Patent 10.7270/Q2V127W1 aid1804493 US10669296 Martinez, EJ; Kaiser, B; Tavazoie, SF; Kurth, I; Gonsalves, FC; Darst, Jr., DM; Tavazoie, MF Rgenix, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=426493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=426493&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 68861577 434320823 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 914107 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 50.0 US Patent 10.7270/Q2V127W1 aid1804493 US10669296 Martinez, EJ; Kaiser, B; Tavazoie, SF; Kurth, I; Gonsalves, FC; Darst, Jr., DM; Tavazoie, MF Rgenix, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 914109 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta 24.0 US Patent 10.7270/Q2V127W1 aid1804493 US10669296 Martinez, EJ; Kaiser, B; Tavazoie, SF; Kurth, I; Gonsalves, FC; Darst, Jr., DM; Tavazoie, MF Rgenix, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270268 Clc1ccccc1-c1n[nH]c(Cc2ccccc2)n1 InChI=1S/C15H12ClN3/c16-13-9-5-4-8-12(13)15-17-14(18-19-15)10-11-6-2-1-3-7-11/h1-9H,10H2,(H,17,18,19) OBYJDAHTJUNYFJ-UHFFFAOYSA-N 50518740 CHEMBL4444106 Oxysterols receptor LXR-beta 966 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155516918 440727322 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270269 CC(=O)n1nc(nc1-c1ccccc1)-c1ccccc1 InChI=1S/C16H13N3O/c1-12(20)19-16(14-10-6-3-7-11-14)17-15(18-19)13-8-4-2-5-9-13/h2-11H,1H3 LOYINMXBROZVLT-UHFFFAOYSA-N 50518741 CHEMBL4475354 Oxysterols receptor LXR-beta 232 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 19835803 440727323 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270284 c1ccc(cc1)-c1n[nH]c(n1)-c1ccccc1 InChI=1S/C14H11N3/c1-3-7-11(8-4-1)13-15-14(17-16-13)12-9-5-2-6-10-12/h1-10H,(H,15,16,17) KPKQWXGFEKRQQA-UHFFFAOYSA-N 50518739 CHEMBL280106 Oxysterols receptor LXR-beta 1008 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16260 440727321 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270285 Brc1ccccc1-c1n[nH]c(n1)-c1ccccc1 InChI=1S/C14H10BrN3/c15-12-9-5-4-8-11(12)14-16-13(17-18-14)10-6-2-1-3-7-10/h1-9H,(H,16,17,18) DIWNQZNKBUKHDH-UHFFFAOYSA-N 50518752 CHEMBL4450521 Oxysterols receptor LXR-beta 493 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 61352587 440727334 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270286 Clc1ccc(cc1)-c1n[nH]c(n1)-c1ccccc1 InChI=1S/C14H10ClN3/c15-12-8-6-11(7-9-12)14-16-13(17-18-14)10-4-2-1-3-5-10/h1-9H,(H,16,17,18) UMZLKCCVHSQEQS-UHFFFAOYSA-N 50518751 CHEMBL4525895 Oxysterols receptor LXR-beta 245 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4730488 440727333 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270287 Brc1ccc(cc1)-c1n[nH]c(n1)-c1ccccc1 InChI=1S/C14H10BrN3/c15-12-8-6-11(7-9-12)14-16-13(17-18-14)10-4-2-1-3-5-10/h1-9H,(H,16,17,18) PLRURNUSAXSWDI-UHFFFAOYSA-N 50518750 CHEMBL4566454 Oxysterols receptor LXR-beta 68 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 61353182 440727332 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270288 COc1cccc(c1)-c1n[nH]c(n1)-c1ccccc1 InChI=1S/C15H13N3O/c1-19-13-9-5-8-12(10-13)15-16-14(17-18-15)11-6-3-2-4-7-11/h2-10H,1H3,(H,16,17,18) TUZKSBDENMZZCL-UHFFFAOYSA-N 50518749 CHEMBL4461852 Oxysterols receptor LXR-beta 68 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518749&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 61343280 440727331 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270289 C(c1nc(n[nH]1)-c1ccccc1)c1ccccc1 InChI=1S/C15H13N3/c1-3-7-12(8-4-1)11-14-16-15(18-17-14)13-9-5-2-6-10-13/h1-10H,11H2,(H,16,17,18) VELJKZCOFOESAQ-UHFFFAOYSA-N 50518748 CHEMBL4451751 Oxysterols receptor LXR-beta 6152 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518748&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 12949989 440727330 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270290 COc1cccc(c1)-c1nc(-c2ccccc2)n(Cc2ccccc2)n1 InChI=1S/C22H19N3O/c1-26-20-14-8-13-19(15-20)21-23-22(18-11-6-3-7-12-18)25(24-21)16-17-9-4-2-5-10-17/h2-15H,16H2,1H3 PCALMCUVCORSKQ-UHFFFAOYSA-N 50518753 CHEMBL4461752 Oxysterols receptor LXR-beta 2365 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518753&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155528665 440727335 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270291 Cn1nc(nc1-c1ccccc1)-c1ccc(Cl)cc1 InChI=1S/C15H12ClN3/c1-19-15(12-5-3-2-4-6-12)17-14(18-19)11-7-9-13(16)10-8-11/h2-10H,1H3 PKKYCXNAJHUXKM-UHFFFAOYSA-N 50518747 CHEMBL4469858 Oxysterols receptor LXR-beta 1985 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 13028610 440727329 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270292 Clc1ccc(cc1)-c1nc(-c2ccccc2)n(Cc2ccccc2)n1 InChI=1S/C21H16ClN3/c22-19-13-11-17(12-14-19)20-23-21(18-9-5-2-6-10-18)25(24-20)15-16-7-3-1-4-8-16/h1-14H,15H2 RZJYQMHZBXVMAL-UHFFFAOYSA-N 50518746 CHEMBL4555548 Oxysterols receptor LXR-beta 6706 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155557200 440727328 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270293 Brc1ccc(cc1)-c1nc(-c2ccccc2)n(Cc2ccccc2)n1 InChI=1S/C21H16BrN3/c22-19-13-11-17(12-14-19)20-23-21(18-9-5-2-6-10-18)25(24-20)15-16-7-3-1-4-8-16/h1-14H,15H2 YCGMRGQWLOCGAN-UHFFFAOYSA-N 50518737 CHEMBL4515644 Oxysterols receptor LXR-beta 712 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155539858 440727319 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270294 CC(=O)n1nc(nc1-c1ccccc1)-c1ccc(Br)cc1 InChI=1S/C16H12BrN3O/c1-11(21)20-16(13-5-3-2-4-6-13)18-15(19-20)12-7-9-14(17)10-8-12/h2-10H,1H3 XPZZEBKIULFCJD-UHFFFAOYSA-N 50518744 CHEMBL4591840 Oxysterols receptor LXR-beta 231 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155568648 440727326 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270295 CC(=O)n1nc(nc1-c1ccccc1)-c1ccc(C)cc1 InChI=1S/C17H15N3O/c1-12-8-10-14(11-9-12)16-18-17(20(19-16)13(2)21)15-6-4-3-5-7-15/h3-11H,1-2H3 OJOSAEZNLXKDQZ-UHFFFAOYSA-N 50518754 CHEMBL4458039 Oxysterols receptor LXR-beta 351 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 24764397 440727336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270296 CC(=O)n1nc(Cc2ccccc2)nc1-c1ccccc1 InChI=1S/C17H15N3O/c1-13(21)20-17(15-10-6-3-7-11-15)18-16(19-20)12-14-8-4-2-5-9-14/h2-11H,12H2,1H3 ZMGSKGBHMNWGPB-UHFFFAOYSA-N 50518743 CHEMBL4441168 Oxysterols receptor LXR-beta 1425 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155515113 440727325 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270297 Cc1ccc(cc1)S(=O)(=O)n1nc(nc1-c1ccccc1)-c1ccccc1 InChI=1S/C21H17N3O2S/c1-16-12-14-19(15-13-16)27(25,26)24-21(18-10-6-3-7-11-18)22-20(23-24)17-8-4-2-5-9-17/h2-15H,1H3 PIQKQJBWSWUDGY-UHFFFAOYSA-N 50518742 CHEMBL4527494 Oxysterols receptor LXR-beta 259 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 86233643 440727324 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270301 Cn1nc(nc1-c1ccccc1)-c1ccccc1 InChI=1S/C15H13N3/c1-18-15(13-10-6-3-7-11-13)16-14(17-18)12-8-4-2-5-9-12/h2-11H,1H3 TWAVESNVRDYFLI-UHFFFAOYSA-N 50518738 CHEMBL1357461 Oxysterols receptor LXR-beta 2637 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 4585579 440727320 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270305 Clc1ccccc1-c1n[nH]c(n1)-c1ccccc1 InChI=1S/C14H10ClN3/c15-12-9-5-4-8-11(12)14-16-13(17-18-14)10-6-2-1-3-7-10/h1-9H,(H,16,17,18) AHWJVKKSEVAPMR-UHFFFAOYSA-N 50518756 CHEMBL1546037 Oxysterols receptor LXR-beta 640 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 644851 440727338 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270306 Cc1ccc(cc1)-c1n[nH]c(n1)-c1ccccc1 InChI=1S/C15H13N3/c1-11-7-9-13(10-8-11)15-16-14(17-18-15)12-5-3-2-4-6-12/h2-10H,1H3,(H,16,17,18) OGSBRDJAMKKTRH-UHFFFAOYSA-N 50518759 CHEMBL275850 Oxysterols receptor LXR-beta 85 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 134528 440727341 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270307 Clc1ccc(cc1)-c1n[nH]c(Cc2ccccc2)n1 InChI=1S/C15H12ClN3/c16-13-8-6-12(7-9-13)15-17-14(18-19-15)10-11-4-2-1-3-5-11/h1-9H,10H2,(H,17,18,19) GMVYCZKAKBUBCZ-UHFFFAOYSA-N 50518760 CHEMBL4458758 Oxysterols receptor LXR-beta 2573 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 912792 440727342 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270308 CCn1nc(nc1-c1ccccc1)-c1ccc(Br)cc1 InChI=1S/C16H14BrN3/c1-2-20-16(13-6-4-3-5-7-13)18-15(19-20)12-8-10-14(17)11-9-12/h3-11H,2H2,1H3 TXRXKFWNCSFLBO-UHFFFAOYSA-N 50518745 CHEMBL4518983 Oxysterols receptor LXR-beta 5647 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155541483 440727327 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51270309 COc1cccc(c1)-c1nc(-c2ccccc2)n(n1)C(C)=O InChI=1S/C17H15N3O2/c1-12(21)20-17(13-7-4-3-5-8-13)18-16(19-20)14-9-6-10-15(11-14)22-2/h3-11H,1-2H3 HTDDITGWSPFJKW-UHFFFAOYSA-N 50518755 CHEMBL4450542 Oxysterols receptor LXR-beta 109 ChEMBL 10.1016/j.bmcl.2018.12.025 10.7270/Q23N26SN 30587446 Goher, SS; Griffett, K; Hegazy, L; Elagawany, M; Arief, MMH; Avdagic, A; Banerjee, S; Burris, TP; Elgendy, B Benha University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50518755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50518755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155521216 440727337 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282152 OC(=O)C1CCC(O)(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H25F8NO6S/c28-19-5-7-20(8-6-19)43(41,42)24(17-1-3-18(4-2-17)25(29,26(30,31)32)27(33,34)35)13-14-36(15-24)22(39)23(40)11-9-16(10-12-23)21(37)38/h1-8,16,40H,9-15H2,(H,37,38)/t16?,23?,24-/m0/s1 BOILSPDFARREIP-ZBYWLKIMSA-N 253141 US9458171, 101 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253141&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217595 346547506 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282153 OC(=O)C12CCC(CC1)(CC2)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H27F8NO5S/c30-20-5-7-21(8-6-20)44(42,43)26(18-1-3-19(4-2-18)27(31,28(32,33)34)29(35,36)37)15-16-38(17-26)22(39)24-9-12-25(13-10-24,14-11-24)23(40)41/h1-8H,9-17H2,(H,40,41)/t24?,25?,26-/m0/s1 BFUUZNNTBJZLDG-WNMGUVTHSA-N 253432 US9458171, 392 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253432&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217858 346547797 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282154 CS(=O)(=O)C1CCC(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H27F8NO5S2/c1-42(38,39)21-10-2-17(3-11-21)23(37)36-15-14-24(16-36,43(40,41)22-12-8-20(28)9-13-22)18-4-6-19(7-5-18)25(29,26(30,31)32)27(33,34)35/h4-9,12-13,17,21H,2-3,10-11,14-16H2,1H3/t17?,21?,24-/m0/s1 ROJWRLPLLGYYCX-PZYUZEHPSA-N 253571 US9458171, 533 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253571&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118207966 346547935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282163 C[C@@]1(CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(O)=O InChI=1S/C28H27F8NO5S/c1-24(23(39)40)12-10-17(11-13-24)22(38)37-15-14-25(16-37,43(41,42)21-8-6-20(29)7-9-21)18-2-4-19(5-3-18)26(30,27(31,32)33)28(34,35)36/h2-9,17H,10-16H2,1H3,(H,39,40)/t17-,24-,25-/m0/s1 GCIQMJRRIADVCD-HDBFHEOPSA-N 253422 US9458171, 382 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253422&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217851 346547787 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282168 OC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C25H23F8NO6S2/c26-18-5-7-19(8-6-18)42(39,40)22(9-12-34(15-22)20(35)21(36)10-13-41(37,38)14-11-21)16-1-3-17(4-2-16)23(27,24(28,29)30)25(31,32)33/h1-8,36H,9-15H2/t22-/m0/s1 YNNSWDHDROBVBW-QFIPXVFZSA-N 253542 US9458171, 502 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253542&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118207841 346547906 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282265 CC[C@@]1(CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(O)=O InChI=1S/C29H29F8NO5S/c1-2-25(24(40)41)13-11-18(12-14-25)23(39)38-16-15-26(17-38,44(42,43)22-9-7-21(30)8-10-22)19-3-5-20(6-4-19)27(31,28(32,33)34)29(35,36)37/h3-10,18H,2,11-17H2,1H3,(H,40,41)/t18-,25-,26-/m0/s1 NMDBMKMFARAOPP-ATANMQQVSA-N 253436 US9458171, 396 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253436&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217863 346547801 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282266 C[C@@]1(CC[C@@H](CC1)C(O)=O)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H27F8NO5S/c1-24(12-10-17(11-13-24)22(38)39)23(40)37-15-14-25(16-37,43(41,42)21-8-6-20(29)7-9-21)18-2-4-19(5-3-18)26(30,27(31,32)33)28(34,35)36/h2-9,17H,10-16H2,1H3,(H,38,39)/t17-,24-,25-/m0/s1 MTGKHQWAOPFIAB-HDBFHEOPSA-N 50522994 CHEMBL4513846 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50522994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50522994&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155539150 440731576 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282267 CC[C@@]1(CC[C@@H](CC1)C(O)=O)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H29F8NO5S/c1-2-25(13-11-18(12-14-25)23(39)40)24(41)38-16-15-26(17-38,44(42,43)22-9-7-21(30)8-10-22)19-3-5-20(6-4-19)27(31,28(32,33)34)29(35,36)37/h3-10,18H,2,11-17H2,1H3,(H,39,40)/t18-,25-,26-/m0/s1 SVRMKEVXYJZNLQ-ATANMQQVSA-N 253427 US9458171, 387 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253427&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217854 346547792 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282268 CO[C@@]1(CC[C@@H](CC1)C(O)=O)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H27F8NO6S/c1-43-24(12-10-17(11-13-24)22(38)39)23(40)37-15-14-25(16-37,44(41,42)21-8-6-20(29)7-9-21)18-2-4-19(5-3-18)26(30,27(31,32)33)28(34,35)36/h2-9,17H,10-16H2,1H3,(H,38,39)/t17-,24+,25-/m0/s1 VOICMNBKPATLIE-AJHZIAPWSA-N 50522997 CHEMBL4532747 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50522997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50522997&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208048 440731579 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282269 COC[C@@]1(CC[C@@H](CC1)C(O)=O)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H29F8NO6S/c1-44-17-25(12-10-18(11-13-25)23(39)40)24(41)38-15-14-26(16-38,45(42,43)22-8-6-21(30)7-9-22)19-2-4-20(5-3-19)27(31,28(32,33)34)29(35,36)37/h2-9,18H,10-17H2,1H3,(H,39,40)/t18-,25-,26-/m0/s1 VTXAHBUSZIDRJU-ATANMQQVSA-N 50522996 CHEMBL4476687 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50522996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50522996&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217871 440731578 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282270 OC(=O)[C@H]1CC[C@@](F)(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H24F9NO5S/c28-19-5-7-20(8-6-19)43(41,42)24(17-1-3-18(4-2-17)25(30,26(31,32)33)27(34,35)36)13-14-37(15-24)22(40)23(29)11-9-16(10-12-23)21(38)39/h1-8,16H,9-15H2,(H,38,39)/t16-,23+,24-/m0/s1 VXQLLPVKMJJWAK-GHEQTVGYSA-N 253426 US9458171, 386 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253426&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217853 346547791 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282271 OC(=O)[C@]1(F)CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H24F9NO5S/c28-19-5-7-20(8-6-19)43(41,42)24(17-1-3-18(4-2-17)25(30,26(31,32)33)27(34,35)36)13-14-37(15-24)21(38)16-9-11-23(29,12-10-16)22(39)40/h1-8,16H,9-15H2,(H,39,40)/t16-,23-,24-/m0/s1 SEPMYXWLNORQTN-ZCWWJEROSA-N 253423 US9458171, 383 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253423&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217852 346547788 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282272 OC(=O)[C@H]1[C@H]2C[C@@H](C[C@@H]12)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H23F8NO5S/c28-17-5-7-18(8-6-17)42(40,41)24(15-1-3-16(4-2-15)25(29,26(30,31)32)27(33,34)35)9-10-36(13-24)22(37)14-11-19-20(12-14)21(19)23(38)39/h1-8,14,19-21H,9-13H2,(H,38,39)/t14-,19-,20+,21-,24-/m0/s1 HNOZQRKROBDUDI-VYNBFOJNSA-N 253444 US9458171, 404 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253444&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217865 346547809 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282273 OC(=O)[C@@H]1[C@H]2C[C@@H](C[C@@H]12)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H23F8NO5S/c28-17-5-7-18(8-6-17)42(40,41)24(15-1-3-16(4-2-15)25(29,26(30,31)32)27(33,34)35)9-10-36(13-24)22(37)14-11-19-20(12-14)21(19)23(38)39/h1-8,14,19-21H,9-13H2,(H,38,39)/t14-,19-,20+,21+,24-/m0/s1 HNOZQRKROBDUDI-LPSQLEIASA-N 253439 US9458171, 399 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253439&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217865 346547804 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282274 OC(=O)C12CCC(CC1)(C2)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H25F8NO5S/c29-19-5-7-20(8-6-19)43(41,42)25(17-1-3-18(4-2-17)26(30,27(31,32)33)28(34,35)36)13-14-37(16-25)21(38)23-9-11-24(15-23,12-10-23)22(39)40/h1-8H,9-16H2,(H,39,40)/t23?,24?,25-/m0/s1 XHTMLUDJBICVHB-STEQJIOHSA-N 253437 US9458171, 397 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253437&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118207907 346547802 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282275 OC(=O)C12CCC(CC1)(OC2)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H25F8NO6S/c29-19-5-7-20(8-6-19)44(41,42)25(17-1-3-18(4-2-17)26(30,27(31,32)33)28(34,35)36)13-14-37(15-25)21(38)24-11-9-23(10-12-24,16-43-24)22(39)40/h1-8H,9-16H2,(H,39,40)/t23?,24?,25-/m0/s1 BVABKVKAEGWJRT-STEQJIOHSA-N 253442 US9458171, 402 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253442&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217868 346547807 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282276 Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)[C@H]1CC[C@@H](CC1)c1nnn[nH]1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F 253441 US9458171, 401 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253441&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217867 346547806 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282277 Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C1CCC2(CC1)NC(=O)NC2=O)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C28H25F8N3O5S/c29-19-5-7-20(8-6-19)45(43,44)25(17-1-3-18(4-2-17)26(30,27(31,32)33)28(34,35)36)13-14-39(15-25)21(40)16-9-11-24(12-10-16)22(41)37-23(42)38-24/h1-8,16H,9-15H2,(H2,37,38,41,42)/t16?,24?,25-/m0/s1 QJZRZLRWRGWGLC-ITNSIVGMSA-N 253445 US9458171, 405::US9458171, 406 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253445&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217870 346547810 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282278 Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C1CCC2(CC1)NC(=O)NC2=O)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C28H25F8N3O5S/c29-19-5-7-20(8-6-19)45(43,44)25(17-1-3-18(4-2-17)26(30,27(31,32)33)28(34,35)36)13-14-39(15-25)21(40)16-9-11-24(12-10-16)22(41)37-23(42)38-24/h1-8,16H,9-15H2,(H2,37,38,41,42)/t16?,24?,25-/m0/s1 QJZRZLRWRGWGLC-ITNSIVGMSA-N 253445 US9458171, 405::US9458171, 406 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253445&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217870 346547810 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282279 CS(=O)(=O)C1CCC(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H27F8NO5S2/c1-42(38,39)21-10-2-17(3-11-21)23(37)36-15-14-24(16-36,43(40,41)22-12-8-20(28)9-13-22)18-4-6-19(7-5-18)25(29,26(30,31)32)27(33,34)35/h4-9,12-13,17,21H,2-3,10-11,14-16H2,1H3/t17?,21?,24-/m0/s1 ROJWRLPLLGYYCX-PZYUZEHPSA-N 253571 US9458171, 533 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253571&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118207966 346547935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282280 OC[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H27F8NO4S/c28-21-9-11-22(12-10-21)41(39,40)24(13-14-36(16-24)23(38)18-3-1-17(15-37)2-4-18)19-5-7-20(8-6-19)25(29,26(30,31)32)27(33,34)35/h5-12,17-18,37H,1-4,13-16H2/t17-,18-,24-/m0/s1 OGSNNIRDUYYPKK-XFAGBWLFSA-N 253554 US9458171, 514 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253554&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217935 346547918 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282281 Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C1CCS(=O)(=O)C1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C24H21F8NO5S2/c25-18-5-7-19(8-6-18)40(37,38)21(10-11-33(14-21)20(34)15-9-12-39(35,36)13-15)16-1-3-17(4-2-16)22(26,23(27,28)29)24(30,31)32/h1-8,15H,9-14H2/t15?,21-/m0/s1 QABINSUJKJJFAK-FXMQYSIJSA-N 253529 US9458171, 489 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253529&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217915 346547893 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282282 Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C1CCS(=O)(=O)C1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C24H21F8NO5S2/c25-18-5-7-19(8-6-18)40(37,38)21(10-11-33(14-21)20(34)15-9-12-39(35,36)13-15)16-1-3-17(4-2-16)22(26,23(27,28)29)24(30,31)32/h1-8,15H,9-14H2/t15?,21-/m0/s1 QABINSUJKJJFAK-FXMQYSIJSA-N 253529 US9458171, 489 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253529&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217915 346547893 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282283 Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C1CCS(=O)(=O)CC1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C25H23F8NO5S2/c26-19-5-7-20(8-6-19)41(38,39)22(11-12-34(15-22)21(35)16-9-13-40(36,37)14-10-16)17-1-3-18(4-2-17)23(27,24(28,29)30)25(31,32)33/h1-8,16H,9-15H2/t22-/m0/s1 ZOHVYFFYFCNUAZ-QFIPXVFZSA-N 253525 US9458171, 485 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253525&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217911 346547889 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282284 CCC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H27F8NO5S2/c1-2-23(12-15-42(38,39)16-13-23)22(37)36-14-11-24(17-36,43(40,41)21-9-7-20(28)8-10-21)18-3-5-19(6-4-18)25(29,26(30,31)32)27(33,34)35/h3-10H,2,11-17H2,1H3/t24-/m0/s1 HQZCXDWOMVTYLT-DEOSSOPVSA-N 253539 US9458171, 499 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253539&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217922 346547903 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282285 Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C1(F)CCS(=O)(=O)CC1)c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F InChI=1S/C25H22F9NO5S2/c26-18-5-7-19(8-6-18)42(39,40)22(9-12-35(15-22)20(36)21(27)10-13-41(37,38)14-11-21)16-1-3-17(4-2-16)23(28,24(29,30)31)25(32,33)34/h1-8H,9-15H2/t22-/m0/s1 MGPUHNPKOGQNGH-QFIPXVFZSA-N 253558 US9458171, 519 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253558&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118208184 346547922 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282286 COC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H25F8NO6S2/c1-41-22(11-14-42(37,38)15-12-22)21(36)35-13-10-23(16-35,43(39,40)20-8-6-19(27)7-9-20)17-2-4-18(5-3-17)24(28,25(29,30)31)26(32,33)34/h2-9H,10-16H2,1H3/t23-/m0/s1 HPMPPPHFZHTUEW-QHCPKHFHSA-N 253544 US9458171, 504 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253544&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217925 346547908 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282306 OC(=O)[C@@]1(F)CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H24F9NO5S/c28-19-5-7-20(8-6-19)43(41,42)24(17-1-3-18(4-2-17)25(30,26(31,32)33)27(34,35)36)13-14-37(15-24)21(38)16-9-11-23(29,12-10-16)22(39)40/h1-8,16H,9-15H2,(H,39,40)/t16-,23+,24-/m0/s1 SEPMYXWLNORQTN-GHEQTVGYSA-N 253425 US9458171, 385 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253425&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217852 346547790 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282307 CCC[C@@]1(CC[C@@H](CC1)C(O)=O)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C30H31F8NO5S/c1-2-13-26(14-11-19(12-15-26)24(40)41)25(42)39-17-16-27(18-39,45(43,44)23-9-7-22(31)8-10-23)20-3-5-21(6-4-20)28(32,29(33,34)35)30(36,37)38/h3-10,19H,2,11-18H2,1H3,(H,40,41)/t19-,26-,27-/m0/s1 SJFLTEYVNDWHPL-DOYMOWJKSA-N 253433 US9458171, 393 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253433&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217859 346547798 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282308 OC(=O)C1CCC(O)(CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H25F8NO6S/c28-19-5-7-20(8-6-19)43(41,42)24(17-1-3-18(4-2-17)25(29,26(30,31)32)27(33,34)35)13-14-36(15-24)22(39)23(40)11-9-16(10-12-23)21(37)38/h1-8,16,40H,9-15H2,(H,37,38)/t16?,23?,24-/m0/s1 BOILSPDFARREIP-ZBYWLKIMSA-N 253141 US9458171, 101 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253141&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217595 346547506 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282309 OC(=O)[C@H]1C[C@H]2[C@@H](C1)[C@@H]2C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H23F8NO5S/c28-17-5-7-18(8-6-17)42(40,41)24(15-1-3-16(4-2-15)25(29,26(30,31)32)27(33,34)35)9-10-36(13-24)22(37)21-19-11-14(23(38)39)12-20(19)21/h1-8,14,19-21H,9-13H2,(H,38,39)/t14-,19-,20+,21+,24-/m0/s1 MVMNXAJUCHJIFB-LPSQLEIASA-N 253440 US9458171, 400 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253440&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217866 346547805 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282310 OC(=O)C12CCC(CC1)(CO2)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H25F8NO6S/c29-19-5-7-20(8-6-19)44(41,42)25(17-1-3-18(4-2-17)26(30,27(31,32)33)28(34,35)36)13-14-37(15-25)21(38)23-9-11-24(12-10-23,22(39)40)43-16-23/h1-8H,9-16H2,(H,39,40)/t23?,24?,25-/m0/s1 XFTCOOLWDUDCCF-STEQJIOHSA-N 253443 US9458171, 403 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253443&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217869 346547808 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282311 COC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H27F8NO5S/c1-42-24(39)18-4-2-17(3-5-18)23(38)37-15-14-25(16-37,43(40,41)22-12-10-21(29)11-13-22)19-6-8-20(9-7-19)26(30,27(31,32)33)28(34,35)36/h6-13,17-18H,2-5,14-16H2,1H3/t17-,18-,25-/m0/s1 FXDAKWRVQKBLSG-RPPIVITFSA-N 253451 US9458171, 411 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253451&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217874 346547815 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282312 O[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H25F8NO4S/c27-19-7-11-21(12-8-19)40(38,39)23(13-14-35(15-23)22(37)16-1-9-20(36)10-2-16)17-3-5-18(6-4-17)24(28,25(29,30)31)26(32,33)34/h3-8,11-12,16,20,36H,1-2,9-10,13-15H2/t16-,20-,23-/m0/s1 QNLMLIHRGZGZRQ-GRWTVWFQSA-N 253557 US9458171, 517 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253557&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118207991 346547921 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282313 CC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H25F8NO5S2/c1-22(11-14-41(37,38)15-12-22)21(36)35-13-10-23(16-35,42(39,40)20-8-6-19(27)7-9-20)17-2-4-18(5-3-17)24(28,25(29,30)31)26(32,33)34/h2-9H,10-16H2,1H3/t23-/m0/s1 IXTMSUQJALQDBC-QHCPKHFHSA-N 253534 US9458171, 494 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253534&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217920 346547898 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282339 OC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H25F8NO5S/c28-20-9-11-21(12-10-20)42(40,41)24(13-14-36(15-24)22(37)16-1-3-17(4-2-16)23(38)39)18-5-7-19(8-6-18)25(29,26(30,31)32)27(33,34)35/h5-12,16-17H,1-4,13-15H2,(H,38,39)/t16-,17-,24-/m0/s1 AVHWMAVUUHFRKE-UAVUOLJFSA-N 253135 US9458171, 95 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253135&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search O5A 6P9F 118208018 346547502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282340 C[C@]1(CC[C@@H](CC1)C(O)=O)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H27F8NO5S/c1-24(12-10-17(11-13-24)22(38)39)23(40)37-15-14-25(16-37,43(41,42)21-8-6-20(29)7-9-21)18-2-4-19(5-3-18)26(30,27(31,32)33)28(34,35)36/h2-9,17H,10-16H2,1H3,(H,38,39)/t17-,24+,25-/m0/s1 MTGKHQWAOPFIAB-AJHZIAPWSA-N 50522995 CHEMBL4583791 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50522995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50522995&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155539150 440731577 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282341 OCC1(CCS(=O)(=O)CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H25F8NO6S2/c27-19-5-7-20(8-6-19)43(40,41)23(17-1-3-18(4-2-17)24(28,25(29,30)31)26(32,33)34)9-12-35(15-23)21(37)22(16-36)10-13-42(38,39)14-11-22/h1-8,36H,9-16H2/t23-/m0/s1 FGMWBGPEMWZHPH-QHCPKHFHSA-N 253615 US9458171, 526 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253615&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118207954 346547979 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51282380 NC(=O)[C@H]1CC[C@@H](CC1)C(=O)N1CC[C@](C1)(c1ccc(cc1)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C27H26F8N2O4S/c28-20-9-11-21(12-10-20)42(40,41)24(13-14-37(15-24)23(39)17-3-1-16(2-4-17)22(36)38)18-5-7-19(8-6-18)25(29,26(30,31)32)27(33,34)35/h5-12,16-17H,1-4,13-15H2,(H2,36,38)/t16-,17-,24-/m0/s1 PPAUGFBGWSYFQG-UAVUOLJFSA-N 253143 US9458171, 103 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2019.06.036 10.7270/Q2R214SG 31257087 Lu, Z; Duan, JJ; Xiao, H; Neels, J; Wu, DR; Weigelt, CA; Sack, JS; Khan, J; Ruzanov, M; An, Y; Yarde, M; Karmakar, A; Vishwakrishnan, S; Baratam, V; Shankarappa, H; Vanteru, S; Babu, V; Basha, M; Kumar Gupta, A; Kumaravel, S; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Murali Dhar, TG Bristol-Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=253143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=253143&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 118217594 346547508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51303626 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 50 ChEMBL 10.1021/acs.jmedchem.8b01848 10.7270/Q2J38X18 30702885 Pollinger, J; Gellrich, L; Schierle, S; Kilu, W; Schmidt, J; Kalinowsky, L; Ohrndorf, J; Kaiser, A; Heering, J; Proschak, E; Merk, D Goethe University Frankfurt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51303730 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 50 ChEMBL 10.1021/acs.jmedchem.8b01848 10.7270/Q2J38X18 30702885 Pollinger, J; Gellrich, L; Schierle, S; Kilu, W; Schmidt, J; Kalinowsky, L; Ohrndorf, J; Kaiser, A; Heering, J; Proschak, E; Merk, D Goethe University Frankfurt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51338699 C[C@H]1C[C@@H](CC[C@H]1C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(O)=O InChI=1S/C30H29F8NO5S/c1-16-14-18(26(41)42)2-9-22(16)25(40)39-13-12-27(45(43,44)21-7-5-20(31)6-8-21)23-10-4-19(15-17(23)3-11-24(27)39)28(32,29(33,34)35)30(36,37)38/h4-8,10,15-16,18,22,24H,2-3,9,11-14H2,1H3,(H,41,42)/t16-,18+,22+,24+,27+/m0/s1 JQORWGARJVSRBA-QOTTZFGFSA-N 50541922 Bms-986251 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.0c00063 10.7270/Q2TH8R8Z 32551004 Cherney, RJ; Cornelius, LAM; Srivastava, A; Weigelt, CA; Marcoux, D; Duan, JJ; Shi, Q; Batt, DG; Liu, Q; Yip, S; Wu, DR; Ruzanov, M; Sack, J; Khan, J; Wang, J; Yarde, M; Cvijic, ME; Mathur, A; Li, S; Shuster, D; Khandelwal, P; Borowski, V; Xie, J; Obermeier, M; Fura, A; Stefanski, K; Cornelius, G; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Carter, PH; Dhar, TGM Bristol Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50541922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50541922&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search R7V 6VQF 132123624 442143485 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51379675 C[C@@](O)(CS(C)(=O)=O)C(=O)N[C@@H]1CC[C@@]2([C@H]1CCc1nc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H26F8N2O6S2/c1-22(38,13-43(2,39)40)21(37)36-19-11-12-23(44(41,42)15-5-3-14(27)4-6-15)16(19)7-9-18-17(23)8-10-20(35-18)24(28,25(29,30)31)26(32,33)34/h3-6,8,10,16,19,38H,7,9,11-13H2,1-2H3,(H,36,37)/t16-,19+,22+,23-/m0/s1 ABWRUZQNZVGUGR-SYMSJMEQSA-N 50557809 CHEMBL4760466 Oxysterols receptor LXR-beta >10000 ChEMBL 10.1021/acsmedchemlett.1c00112 10.7270/Q21R6V6T 34055233 Liu, Q; Xiao, HY; Batt, DG; Xiao, Z; Zhu, Y; Yang, MG; Li, N; Yip, S; Li, P; Sun, D; Wu, DR; Ruzanov, M; Sack, JS; Weigelt, CA; Wang, J; Li, S; Shuster, DJ; Xie, JH; Song, Y; Sherry, T; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Chacko, S; Khandelwal, P; Dudhgaonkar, S; Rudra, A; Nagar, J; Murali, V; Govindarajan, A; Denton, R; Zhao, Q; Meanwell, NA; Borzilleri, R; Dhar, TGM Bristol Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50557809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50557809&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search YDY 7LUK 155907524 461828201 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51386730 C[C@@]1(CN(C[C@H]1c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)C(=O)C1CCN(CC1)C(=O)CC#N)c1ccc(F)cc1 InChI=1S/C29H28F7N3O3/c1-26(20-6-8-22(30)9-7-20)17-39(25(41)19-11-14-38(15-12-19)24(40)10-13-37)16-23(26)18-2-4-21(5-3-18)27(42,28(31,32)33)29(34,35)36/h2-9,19,23,42H,10-12,14-17H2,1H3/t23-,26+/m0/s1 JACZDQDBHYAEIU-JYFHCDHNSA-N 510665 US11078186, Example 119 Oxysterols receptor LXR-beta 1130 ChEMBL 10.1016/j.bmcl.2020.127392 10.7270/Q2B56PFT 32738966 Jiang, B; Duan, JJ; Stachura, S; Karmakar, A; Hemagiri, H; Raut, DK; Gupta, AK; Weigelt, CA; Khan, J; Sack, JS; Wu, DR; Yarde, M; Shen, DR; Galella, MA; Mathur, A; Zhao, Q; Salter-Cid, LM; Carter, PH; Dhar, TGM Bristol Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=510665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=510665&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 153313942 459627935 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51369271 C[C@H]1C[C@@H](CC[C@H]1C(=O)N1CC[C@@]2([C@H]1CCc1cc(c(F)cc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1)C(O)=O InChI=1S/C30H29F8NO5S/c1-16-13-18(26(41)42)7-9-20(16)25(40)39-12-11-27(45(43,44)19-5-3-2-4-6-19)21-15-23(31)22(14-17(21)8-10-24(27)39)28(32,29(33,34)35)30(36,37)38/h2-6,14-16,18,20,24H,7-13H2,1H3,(H,41,42)/t16-,18+,20+,24+,27+/m0/s1 ZRBKKZYWZRWOFL-GSDLGJSISA-N 50553584 CHEMBL4763134 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1016/j.bmcl.2020.127521 10.7270/Q2SN0DMB 32882417 Shi, Q; Xiao, Z; Yang, MG; Marcoux, D; Cherney, RJ; Yip, S; Li, P; Wu, DR; Weigelt, CA; Sack, J; Khan, J; Ruzanov, M; Wang, J; Yarde, M; Ellen Cvijic, M; Li, S; Shuster, DJ; Xie, J; Sherry, T; Obermeier, M; Fura, A; Stefanski, K; Cornelius, G; Chacko, S; Shu, YZ; Khandelwal, P; Hynes, J; Tino, JA; Salter-Cid, L; Denton, R; Zhao, Q; Dhar, TGM Bristol Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50553584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50553584&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 146257125 461692352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365523 CC(C)(C)OC(=O)N1CC[C@@]2([C@H]1c1cccc(c1)-c1ccccc1)C(=O)Nc1ccccc21 InChI=1S/C28H28N2O3/c1-27(2,3)33-26(32)30-17-16-28(22-14-7-8-15-23(22)29-25(28)31)24(30)21-13-9-12-20(18-21)19-10-5-4-6-11-19/h4-15,18,24H,16-17H2,1-3H3,(H,29,31)/t24-,28-/m1/s1 HNKXJPOYCMLZTF-UFHPHHKVSA-N 50551960 CHEMBL4791235 Oxysterols receptor LXR-beta 1700 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551960&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162671775 461682300 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365524 CC(C)(C)OC(=O)N1CC[C@]2([C@@H]1c1cccc(c1)-c1ccccc1)C(=O)Nc1ccccc21 InChI=1S/C28H28N2O3/c1-27(2,3)33-26(32)30-17-16-28(22-14-7-8-15-23(22)29-25(28)31)24(30)21-13-9-12-20(18-21)19-10-5-4-6-11-19/h4-15,18,24H,16-17H2,1-3H3,(H,29,31)/t24-,28-/m0/s1 HNKXJPOYCMLZTF-CUBQBAPOSA-N 50551961 CHEMBL4791199 Oxysterols receptor LXR-beta 600 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551961&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162671542 461682301 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365525 CC(C)(C)OC(=O)N1CC[C@@]2([C@H]1c1cccc(c1)-c1ccc(CO)cc1)C(=O)Nc1ccccc21 InChI=1S/C29H30N2O4/c1-28(2,3)35-27(34)31-16-15-29(23-9-4-5-10-24(23)30-26(29)33)25(31)22-8-6-7-21(17-22)20-13-11-19(18-32)12-14-20/h4-14,17,25,32H,15-16,18H2,1-3H3,(H,30,33)/t25-,29-/m1/s1 FURDMJUQRNNUHH-VAVYLYDRSA-N 50551962 CHEMBL4781683 Oxysterols receptor LXR-beta 196 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551962&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162664130 461682302 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365526 CN(C)C(=O)c1ccc(cc1Cl)-c1cccc(c1)[C@H]1N(CC[C@]11C(=O)Nc2ccccc12)C(=O)OC(C)(C)C InChI=1S/C31H32ClN3O4/c1-30(2,3)39-29(38)35-16-15-31(23-11-6-7-12-25(23)33-28(31)37)26(35)21-10-8-9-19(17-21)20-13-14-22(24(32)18-20)27(36)34(4)5/h6-14,17-18,26H,15-16H2,1-5H3,(H,33,37)/t26-,31-/m1/s1 RLOGLAOMVVXPAF-MXBOTTGLSA-N 50551963 CHEMBL4764539 Oxysterols receptor LXR-beta 265 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551963&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162662112 461682303 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365527 CC(C)(C)OC(=O)N1CC[C@@]2([C@H]1c1cccc(c1)-c1cccc(c1)S(C)(=O)=O)C(=O)Nc1ccccc21 InChI=1S/C29H30N2O5S/c1-28(2,3)36-27(33)31-16-15-29(23-13-5-6-14-24(23)30-26(29)32)25(31)21-11-7-9-19(17-21)20-10-8-12-22(18-20)37(4,34)35/h5-14,17-18,25H,15-16H2,1-4H3,(H,30,32)/t25-,29-/m1/s1 UDPMDXUGCPQCIS-VAVYLYDRSA-N 50551958 CHEMBL4780872 Oxysterols receptor LXR-beta 149 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551958&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162663627 461682298 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365528 CC(C)(C)OC(=O)N1CC[C@@]2([C@H]1c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)Nc1ccccc21 InChI=1S/C30H32N2O6S/c1-29(2,3)38-28(35)32-15-14-30(23-10-5-6-11-24(23)31-27(30)34)26(32)21-9-7-8-19(16-21)20-12-13-22(18-33)25(17-20)39(4,36)37/h5-13,16-17,26,33H,14-15,18H2,1-4H3,(H,31,34)/t26-,30-/m1/s1 WCOXMLFEWOILDZ-PDDLMNHVSA-N 50551956 CHEMBL4756418 Oxysterols receptor LXR-beta 1.000000 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551956&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search D3R 6K9G 146020554 461682296 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365529 CC(C)(C)OC(=O)N1CC[C@]2([C@@H]1c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)Nc1ccccc21 InChI=1S/C30H32N2O6S/c1-29(2,3)38-28(35)32-15-14-30(23-10-5-6-11-24(23)31-27(30)34)26(32)21-9-7-8-19(16-21)20-12-13-22(18-33)25(17-20)39(4,36)37/h5-13,16-17,26,33H,14-15,18H2,1-4H3,(H,31,34)/t26-,30-/m0/s1 WCOXMLFEWOILDZ-YZNIXAGQSA-N 50551955 CHEMBL4777240 Oxysterols receptor LXR-beta 135 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551955&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162643175 461682295 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365530 COC(=O)c1ccc(cc1S(C)(=O)=O)-c1cccc(c1)[C@H]1N(CC[C@]11C(=O)Nc2ccccc12)C(=O)OC(C)(C)C InChI=1S/C31H32N2O7S/c1-30(2,3)40-29(36)33-16-15-31(23-11-6-7-12-24(23)32-28(31)35)26(33)21-10-8-9-19(17-21)20-13-14-22(27(34)39-4)25(18-20)41(5,37)38/h6-14,17-18,26H,15-16H2,1-5H3,(H,32,35)/t26-,31-/m1/s1 CSIIUZYJPVSIJG-MXBOTTGLSA-N 50551953 CHEMBL4764838 Oxysterols receptor LXR-beta 37 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551953&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162662305 461682293 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365531 COC(=O)c1ccc(cc1S(C)(=O)=O)-c1cccc(c1)[C@@H]1N(CC[C@@]11C(=O)Nc2ccccc12)C(=O)OC(C)(C)C InChI=1S/C31H32N2O7S/c1-30(2,3)40-29(36)33-16-15-31(23-11-6-7-12-24(23)32-28(31)35)26(33)21-10-8-9-19(17-21)20-13-14-22(27(34)39-4)25(18-20)41(5,37)38/h6-14,17-18,26H,15-16H2,1-5H3,(H,32,35)/t26-,31-/m0/s1 CSIIUZYJPVSIJG-HVNZXBJASA-N 50551952 CHEMBL4762542 Oxysterols receptor LXR-beta 1200 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551952&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162659463 461682292 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365532 CC(C)(C)OC(=O)N1CC[C@@]2([C@H]1c1cccc(c1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O)C(=O)Nc1ccccc21 InChI=1S/C30H31FN2O6S/c1-29(2,3)39-28(36)33-13-12-30(22-10-5-6-11-24(22)32-27(30)35)26(33)19-9-7-8-18(14-19)20-15-23(31)21(17-34)25(16-20)40(4,37)38/h5-11,14-16,26,34H,12-13,17H2,1-4H3,(H,32,35)/t26-,30-/m1/s1 HYQGRYRHNUHTJF-PDDLMNHVSA-N 50551950 CHEMBL4757761 Oxysterols receptor LXR-beta 68 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551950&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162656810 461682290 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365533 CC(C)(C)OC(=O)N1CC[C@]2([C@@H]1c1cccc(c1)-c1cc(F)c(CO)c(c1)S(C)(=O)=O)C(=O)Nc1ccccc21 InChI=1S/C30H31FN2O6S/c1-29(2,3)39-28(36)33-13-12-30(22-10-5-6-11-24(22)32-27(30)35)26(33)19-9-7-8-18(14-19)20-15-23(31)21(17-34)25(16-20)40(4,37)38/h5-11,14-16,26,34H,12-13,17H2,1-4H3,(H,32,35)/t26-,30-/m0/s1 HYQGRYRHNUHTJF-YZNIXAGQSA-N 50551949 CHEMBL4762546 Oxysterols receptor LXR-beta 133 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551949&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162659570 461682289 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365534 CC(C)(C)OC(=O)N1CC[C@@]2([C@H]1c1cccc(Nc3ccc(CO)c(c3)S(C)(=O)=O)c1)C(=O)Nc1ccccc21 InChI=1S/C30H33N3O6S/c1-29(2,3)39-28(36)33-15-14-30(23-10-5-6-11-24(23)32-27(30)35)26(33)19-8-7-9-21(16-19)31-22-13-12-20(18-34)25(17-22)40(4,37)38/h5-13,16-17,26,31,34H,14-15,18H2,1-4H3,(H,32,35)/t26-,30-/m1/s1 YIKYKYFYFWNCSE-PDDLMNHVSA-N 50551947 CHEMBL4797369 Oxysterols receptor LXR-beta 101 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551947&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162675955 461682287 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365535 CC(C)(C)OC(=O)N1CC[C@]2([C@@H]1c1cccc(Nc3ccc(CO)c(c3)S(C)(=O)=O)c1)C(=O)Nc1ccccc21 InChI=1S/C30H33N3O6S/c1-29(2,3)39-28(36)33-15-14-30(23-10-5-6-11-24(23)32-27(30)35)26(33)19-8-7-9-21(16-19)31-22-13-12-20(18-34)25(17-22)40(4,37)38/h5-13,16-17,26,31,34H,14-15,18H2,1-4H3,(H,32,35)/t26-,30-/m0/s1 YIKYKYFYFWNCSE-YZNIXAGQSA-N 50551944 CHEMBL4748480 Oxysterols receptor LXR-beta 234 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551944&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162649663 461682284 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365536 CC(C)(C)CC(=O)N1CC[C@@]2([C@H]1c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)Nc1ccccc21 InChI=1S/C31H34N2O5S/c1-30(2,3)18-27(35)33-15-14-31(24-10-5-6-11-25(24)32-29(31)36)28(33)22-9-7-8-20(16-22)21-12-13-23(19-34)26(17-21)39(4,37)38/h5-13,16-17,28,34H,14-15,18-19H2,1-4H3,(H,32,36)/t28-,31-/m1/s1 CUNZKYVACXRKTP-GRKNLSHJSA-N 50551946 CHEMBL4764328 Oxysterols receptor LXR-beta 7.3 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551946&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162661032 461682286 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365537 CC(C)(C)CC(=O)N1CC[C@]2([C@@H]1c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)Nc1ccccc21 InChI=1S/C31H34N2O5S/c1-30(2,3)18-27(35)33-15-14-31(24-10-5-6-11-25(24)32-29(31)36)28(33)22-9-7-8-20(16-22)21-12-13-23(19-34)26(17-21)39(4,37)38/h5-13,16-17,28,34H,14-15,18-19H2,1-4H3,(H,32,36)/t28-,31-/m0/s1 CUNZKYVACXRKTP-IZEXYCQBSA-N 50551964 CHEMBL4745005 Oxysterols receptor LXR-beta 70 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50551964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50551964&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162648696 461682304 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365538 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 41 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365539 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta 2.2 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51365540 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta 14 ChEMBL 10.1016/j.ejmech.2020.112240 10.7270/Q2MG7T4D 32248003 Chen, H; Chen, Z; Zhang, Z; Li, Y; Zhang, S; Jiang, F; Wei, J; Ding, P; Zhou, H; Gu, Q; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51354718 CC(C)(O)CN1[C@@H](C[C@@H](F)C1=O)C(=O)N1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C30H29F9N2O5S/c1-26(2,44)15-41-22(14-21(32)24(41)42)25(43)40-12-11-27(47(45,46)19-7-5-18(31)6-8-19)20-9-4-17(13-16(20)3-10-23(27)40)28(33,29(34,35)36)30(37,38)39/h4-9,13,21-23,44H,3,10-12,14-15H2,1-2H3/t21-,22+,23-,27-/m1/s1 NETWYXYMXZLUOG-QSGNWFJVSA-N 50548025 CHEMBL4782326 Oxysterols receptor LXR-beta >7500 ChEMBL 10.1021/acsmedchemlett.0c00496 10.7270/Q2MS3XBX 33335675 Liu, Q; Batt, DG; Weigelt, CA; Yip, S; Wu, DR; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Li, S; Shuster, DJ; Xie, JH; Sherry, T; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Khandelwal, P; Tino, JA; Macor, JE; Salter-Cid, L; Denton, R; Zhao, Q; Dhar, TGM Bristol Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50548025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50548025&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search Z8I 7JYM 155289164 461678365 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51360751 CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)CC[C@@H](O)C[C@@H]12 InChI=1S/C26H44O5/c1-5-16-19-12-15(27)10-11-25(19,3)23-20(28)13-26(4)17(14(2)6-9-21(29)30)7-8-18(26)22(23)24(16)31/h14-20,22-24,27-28,31H,5-13H2,1-4H3,(H,29,30)/t14-,15-,16-,17-,18+,19+,20+,22+,23+,24-,25+,26-/m1/s1 UEXTVLKDFZEPMH-PAEMJXPASA-N 50550152 CHEMBL4758064 Oxysterols receptor LXR-beta >100000 ChEMBL 10.1021/acs.jmedchem.6b01126 10.7270/Q2DF6VVN 27652492 Pellicciari, R; Passeri, D; De Franco, F; Mostarda, S; Filipponi, P; Colliva, C; Gadaleta, RM; Franco, P; Carotti, A; Macchiarulo, A; Roda, A; Moschetta, A; Gioiello, A TES Pharma S.r.l. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50550152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50550152&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 86280678 461680492 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51360752 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 10.0 ChEMBL 10.1021/acs.jmedchem.6b01126 10.7270/Q2DF6VVN 27652492 Pellicciari, R; Passeri, D; De Franco, F; Mostarda, S; Filipponi, P; Colliva, C; Gadaleta, RM; Franco, P; Carotti, A; Macchiarulo, A; Roda, A; Moschetta, A; Gioiello, A TES Pharma S.r.l. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400548 CCOC(=O)c1ccc(CN(Cc2ccc(cc2)-c2cccc(c2)S(C)(=O)=O)S(=O)(=O)c2c(C)cc(C)cc2C)o1 InChI=1S/C31H33NO7S2/c1-6-38-31(33)29-15-14-27(39-29)20-32(41(36,37)30-22(3)16-21(2)17-23(30)4)19-24-10-12-25(13-11-24)26-8-7-9-28(18-26)40(5,34)35/h7-18H,6,19-20H2,1-5H3 HDZWHJYZJWLTAG-UHFFFAOYSA-N 50465712 CHEMBL4284414 Oxysterols receptor LXR-beta 100 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465712&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71478195 433932977 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400549 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)OC(C)(C)C InChI=1S/C33H38N2O6S/c1-21(2)29-33(16-17-34(29)31(38)41-32(3,4)5)26-12-7-8-13-27(26)35(30(33)37)25-11-9-10-22(18-25)23-14-15-24(20-36)28(19-23)42(6,39)40/h7-15,18-19,21,29,36H,16-17,20H2,1-6H3/t29-,33-/m0/s1 ZWVQGRNZPMCKOJ-ZQAZVOLISA-N 50565754 CHEMBL4794621 Oxysterols receptor LXR-beta 390 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162672388 461686092 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400550 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)CC(C)(C)C InChI=1S/C34H40N2O5S/c1-22(2)31-34(16-17-35(31)30(38)20-33(3,4)5)27-12-7-8-13-28(27)36(32(34)39)26-11-9-10-23(18-26)24-14-15-25(21-37)29(19-24)42(6,40)41/h7-15,18-19,22,31,37H,16-17,20-21H2,1-6H3/t31-,34-/m0/s1 CJRGDJGNDOAXBL-VBTAUBHQSA-N 50565755 CHEMBL4796152 Oxysterols receptor LXR-beta 1790 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162672437 461686093 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400551 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)C(C)(C)C InChI=1S/C33H38N2O5S/c1-21(2)29-33(16-17-34(29)30(37)32(3,4)5)26-12-7-8-13-27(26)35(31(33)38)25-11-9-10-22(18-25)23-14-15-24(20-36)28(19-23)41(6,39)40/h7-15,18-19,21,29,36H,16-17,20H2,1-6H3/t29-,33-/m0/s1 ZFNSEUOEUALZPD-ZQAZVOLISA-N 50565756 CHEMBL4798878 Oxysterols receptor LXR-beta 2400 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162675580 461686094 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400552 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)C(F)(F)F InChI=1S/C30H29F3N2O5S/c1-18(2)26-29(13-14-34(26)28(38)30(31,32)33)23-9-4-5-10-24(23)35(27(29)37)22-8-6-7-19(15-22)20-11-12-21(17-36)25(16-20)41(3,39)40/h4-12,15-16,18,26,36H,13-14,17H2,1-3H3/t26-,29-/m0/s1 DZRWUTGASMVWBJ-WNJJXGMVSA-N 50565757 CHEMBL4795380 Oxysterols receptor LXR-beta 3440 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565757&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162674218 461686095 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400553 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(C(O)=O)c(c1)S(C)(=O)=O)C(=O)OC(C)(C)C InChI=1S/C33H36N2O7S/c1-20(2)28-33(16-17-34(28)31(39)42-32(3,4)5)25-12-7-8-13-26(25)35(30(33)38)23-11-9-10-21(18-23)22-14-15-24(29(36)37)27(19-22)43(6,40)41/h7-15,18-20,28H,16-17H2,1-6H3,(H,36,37)/t28-,33-/m0/s1 JMANSVHLXPEHIF-UVMMSNCQSA-N 50565761 CHEMBL4789739 Oxysterols receptor LXR-beta 10080 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565761&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162668920 461686099 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400554 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(Cl)c1)C(=O)OC(C)(C)C InChI=1S/C32H35ClN2O4/c1-20(2)28-32(15-16-34(28)30(38)39-31(3,4)5)25-11-6-7-12-27(25)35(29(32)37)24-10-8-9-21(17-24)22-13-14-23(19-36)26(33)18-22/h6-14,17-18,20,28,36H,15-16,19H2,1-5H3/t28-,32-/m0/s1 IQSOORUBJUWRBN-IUDBTDONSA-N 50565762 CHEMBL4794355 Oxysterols receptor LXR-beta 6970 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565762&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162673421 461686100 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400555 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)cc1)C(=O)OC(C)(C)C InChI=1S/C32H36N2O4/c1-21(2)28-32(17-18-33(28)30(37)38-31(3,4)5)26-11-6-7-12-27(26)34(29(32)36)25-10-8-9-24(19-25)23-15-13-22(20-35)14-16-23/h6-16,19,21,28,35H,17-18,20H2,1-5H3/t28-,32-/m0/s1 LAIOOQXQYNCRKH-IUDBTDONSA-N 50565763 CHEMBL4783737 Oxysterols receptor LXR-beta 8640 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565763&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162665441 461686101 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400556 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(C(=O)N(C)C)c(Cl)c1)C(=S)NC(C)(C)C InChI=1S/C34H39ClN4O2S/c1-21(2)29-34(17-18-38(29)32(42)36-33(3,4)5)26-13-8-9-14-28(26)39(31(34)41)24-12-10-11-22(19-24)23-15-16-25(27(35)20-23)30(40)37(6)7/h8-16,19-21,29H,17-18H2,1-7H3,(H,36,42)/t29-,34-/m0/s1 HQPVSZHQXIYMRT-DODOAAEWSA-N 50565758 CHEMBL4782751 Oxysterols receptor LXR-beta 1430 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565758&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162664369 461686096 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400557 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(C(=O)N(C)C)c(Cl)c1)S(=O)(=O)C(C)C InChI=1S/C32H36ClN3O4S/c1-20(2)29-32(16-17-35(29)41(39,40)21(3)4)26-12-7-8-13-28(26)36(31(32)38)24-11-9-10-22(18-24)23-14-15-25(27(33)19-23)30(37)34(5)6/h7-15,18-21,29H,16-17H2,1-6H3/t29-,32-/m0/s1 JSOVILRYKGQEGO-NYDCQLBNSA-N 50565759 CHEMBL4781674 Oxysterols receptor LXR-beta 4570 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162664025 461686097 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400558 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc2ccn(C)c2c1)C(=O)OC(C)(C)C InChI=1S/C34H37N3O3/c1-22(2)30-34(17-19-36(30)32(39)40-33(3,4)5)27-12-7-8-13-28(27)37(31(34)38)26-11-9-10-24(20-26)25-15-14-23-16-18-35(6)29(23)21-25/h7-16,18,20-22,30H,17,19H2,1-6H3/t30-,34-/m0/s1 NANNOADHYLZMPU-NHZFLZHXSA-N 50565764 CHEMBL4781197 Oxysterols receptor LXR-beta >20000 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565764&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162663651 461686102 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400559 CC(C)[C@H]1N(CC[C@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)OC(C)(C)C InChI=1S/C33H38N2O6S/c1-21(2)29-33(16-17-34(29)31(38)41-32(3,4)5)26-12-7-8-13-27(26)35(30(33)37)25-11-9-10-22(18-25)23-14-15-24(20-36)28(19-23)42(6,39)40/h7-15,18-19,21,29,36H,16-17,20H2,1-6H3/t29-,33-/m1/s1 ZWVQGRNZPMCKOJ-CYTLCNBWSA-N 50565760 CHEMBL4787419 Oxysterols receptor LXR-beta 360 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162667159 461686098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400560 CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)OC(C)(C)C InChI=1S/C33H38N2O6S/c1-21(2)29-33(16-17-34(29)31(38)41-32(3,4)5)26-12-7-8-13-27(26)35(30(33)37)25-11-9-10-22(18-25)23-14-15-24(20-36)28(19-23)42(6,39)40/h7-15,18-19,21,29,36H,16-17,20H2,1-6H3/t29-,33-/m0/s1 ZWVQGRNZPMCKOJ-ZQAZVOLISA-N 50565754 CHEMBL4794621 Oxysterols receptor LXR-beta 390 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162672388 461686092 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51400561 CC(C)[C@H]1N(CC[C@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(CO)c(c1)S(C)(=O)=O)C(=O)OC(C)(C)C InChI=1S/C33H38N2O6S/c1-21(2)29-33(16-17-34(29)31(38)41-32(3,4)5)26-12-7-8-13-27(26)35(30(33)37)25-11-9-10-22(18-25)23-14-15-24(20-36)28(19-23)42(6,39)40/h7-15,18-19,21,29,36H,16-17,20H2,1-6H3/t29-,33-/m1/s1 ZWVQGRNZPMCKOJ-CYTLCNBWSA-N 50565760 CHEMBL4787419 Oxysterols receptor LXR-beta 2300 ChEMBL 10.1016/j.ejmech.2020.112793 10.7270/Q2RB78BB 32961480 Chen, Z; Chen, H; Zhang, Z; Ding, P; Yan, X; Li, Y; Zhang, S; Gu, Q; Zhou, H; Xu, J Sun Yat-Sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50565760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50565760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 162667159 461686098 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51416670 OC(=O)c1cc(c2cc(ccc2n1)N1CCC2(CC(=C2)c2c(onc2-c2c(Cl)cncc2Cl)C2CC2)CC1)C(F)(F)F InChI=1S/C30H23Cl2F3N4O3/c31-20-13-36-14-21(32)25(20)26-24(27(42-38-26)15-1-2-15)16-11-29(12-16)5-7-39(8-6-29)17-3-4-22-18(9-17)19(30(33,34)35)10-23(37-22)28(40)41/h3-4,9-11,13-15H,1-2,5-8,12H2,(H,40,41) WPGAVSDZYIRUGE-UHFFFAOYSA-N 50572221 CHEMBL4862974 Oxysterols receptor LXR-beta >40000 ChEMBL 10.1021/acsmedchemlett.1c00198 10.7270/Q24M98B8 34531950 Carpenter, J; Wu, G; Wang, Y; Cook, EM; Wang, T; Sitkoff, D; Rossi, KA; Mosure, K; Zhuo, X; Cao, GG; Ziegler, M; Azzara, AV; Krupinski, J; Soars, MG; Ellsworth, BA; Wacker, DA Bristol-Myers Squibb http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50572221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50572221&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 138592025 471062366 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51411663 CC(C)(O)C(=O)N[C@@H]1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H25F8NO4S/c1-22(2,37)21(36)35-20-11-12-23(40(38,39)17-7-5-16(27)6-8-17)18-10-4-15(13-14(18)3-9-19(20)23)24(28,25(29,30)31)26(32,33)34/h4-8,10,13,19-20,37H,3,9,11-12H2,1-2H3,(H,35,36)/t19-,20+,23+/m0/s1 JZUVTKBHDNIOHD-MIZPHKNDSA-N 414250 US10435369, Example 137 Oxysterols receptor LXR-beta >5000 ChEMBL 10.1021/acs.jmedchem.0c01992 10.7270/Q2N87FJG 33591748 Yang, MG; Beaudoin-Bertrand, M; Xiao, Z; Marcoux, D; Weigelt, CA; Yip, S; Wu, DR; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Li, S; Shuster, DJ; Xie, JH; Sherry, T; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Khandelwal, P; Karmakar, A; Basha, M; Babu, V; Gupta, AK; Mathur, A; Salter-Cid, L; Denton, R; Zhao, Q; Dhar, TGM Bristol Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=414250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=414250&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search Z8G 7KQJ 134491220 433914336 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51411664 C[C@H]1C[C@@H](CC[C@H]1NN1CC[C@@]2([C@H]1CCc1cc(ccc21)C(F)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccc(F)cc1)C(O)=O InChI=1S/C29H30F8N2O4S/c1-16-14-18(25(40)41)2-10-23(16)38-39-13-12-26(44(42,43)21-7-5-20(30)6-8-21)22-9-4-19(15-17(22)3-11-24(26)39)27(31,28(32,33)34)29(35,36)37/h4-9,15-16,18,23-24,38H,2-3,10-14H2,1H3,(H,40,41)/t16-,18+,23+,24+,26+/m0/s1 MUHYHLFUAPFACM-FIHPKFJVSA-N 50570328 CHEMBL4871326 Oxysterols receptor LXR-beta >5000 ChEMBL 10.1021/acs.jmedchem.0c01992 10.7270/Q2N87FJG 33591748 Yang, MG; Beaudoin-Bertrand, M; Xiao, Z; Marcoux, D; Weigelt, CA; Yip, S; Wu, DR; Ruzanov, M; Sack, JS; Wang, J; Yarde, M; Li, S; Shuster, DJ; Xie, JH; Sherry, T; Obermeier, MT; Fura, A; Stefanski, K; Cornelius, G; Khandelwal, P; Karmakar, A; Basha, M; Babu, V; Gupta, AK; Mathur, A; Salter-Cid, L; Denton, R; Zhao, Q; Dhar, TGM Bristol Myers Squibb Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570328&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 164619865 471060473 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51491169 OC(c1ccc(cc1)N(C(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C16H10F9NO3S/c17-14(18,19)13(27,15(20,21)22)10-6-8-11(9-7-10)26(16(23,24)25)30(28,29)12-4-2-1-3-5-12/h1-9,27H NVKWDEFHOMJOQR-UHFFFAOYSA-N 50600999 CHEMBL5192460 Oxysterols receptor LXR-beta 20 ChEMBL 10.7270/Q2K35ZR8 35797110 Shim, S; Krishnaiah, M; Sankham, MR; Kim, I; Lee, Y; Shin, I; Oh, AR; Lee, HJ; Vu, TNL; Park, J; Choi, S; Park, S; Kwon, Y; Fang, S; Kim, DK Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600999&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168286972 482611851 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490161 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta 260 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490162 CN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1 InChI=1S/C16H13F6NO3S/c1-23(27(25,26)13-5-3-2-4-6-13)12-9-7-11(8-10-12)14(24,15(17,18)19)16(20,21)22/h2-10,24H,1H3 CNVKZYLQZYULJV-UHFFFAOYSA-N 50179869 CHEMBL203682::N-methyl-N-[4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-benzenesulfonamide Oxysterols receptor LXR-beta 2930 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50179869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50179869&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 0KS 4DK7 10112384 104065016 CHEMBL203682 ZINC01906924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490163 C[Si](C)(C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C12H14F6OSi/c1-20(2,3)9-6-4-8(5-7-9)10(19,11(13,14)15)12(16,17)18/h4-7,19H,1-3H3 VQIGQFMEPHTOIB-UHFFFAOYSA-N 50600554 CHEMBL5173460 Oxysterols receptor LXR-beta 1410 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600554&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168274429 482611406 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490164 CC[Si](CC)(CC)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C15H20F6OSi/c1-4-23(5-2,6-3)12-9-7-11(8-10-12)13(22,14(16,17)18)15(19,20)21/h7-10,22H,4-6H2,1-3H3 PTXBZMKOPNEAML-UHFFFAOYSA-N 50600555 CHEMBL5173224 Oxysterols receptor LXR-beta 530 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600555&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168272454 482611407 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490165 CCC[Si](CCC)(CCC)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C18H26F6OSi/c1-4-11-26(12-5-2,13-6-3)15-9-7-14(8-10-15)16(25,17(19,20)21)18(22,23)24/h7-10,25H,4-6,11-13H2,1-3H3 JHEDEVPRZXMGKU-UHFFFAOYSA-N 50600556 CHEMBL5203561 Oxysterols receptor LXR-beta 590 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600556&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168293391 482611408 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490166 OC(c1ccc(cc1)[Si](Cc1ccccc1)(Cc1ccccc1)Cc1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C30H26F6OSi/c31-29(32,33)28(37,30(34,35)36)26-16-18-27(19-17-26)38(20-23-10-4-1-5-11-23,21-24-12-6-2-7-13-24)22-25-14-8-3-9-15-25/h1-19,37H,20-22H2 WKXKAKRVCIDNQA-UHFFFAOYSA-N 50600557 CHEMBL5200504 Oxysterols receptor LXR-beta 1980 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600557&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168291313 482611409 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490167 C[Si](C)(C=C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C13H14F6OSi/c1-4-21(2,3)10-7-5-9(6-8-10)11(20,12(14,15)16)13(17,18)19/h4-8,20H,1H2,2-3H3 SXZWTVJONJUMMI-UHFFFAOYSA-N 50600558 CHEMBL5182815 Oxysterols receptor LXR-beta 1800 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600558&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168282075 482611410 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490168 C[Si](C)(CC=C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C14H16F6OSi/c1-4-9-22(2,3)11-7-5-10(6-8-11)12(21,13(15,16)17)14(18,19)20/h4-8,21H,1,9H2,2-3H3 ULUFHBNVVKMYSI-UHFFFAOYSA-N 50600559 CHEMBL5183659 Oxysterols receptor LXR-beta 450 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600559&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168282113 482611411 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490169 CCCC[Si](C)(C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C15H20F6OSi/c1-4-5-10-23(2,3)12-8-6-11(7-9-12)13(22,14(16,17)18)15(19,20)21/h6-9,22H,4-5,10H2,1-3H3 NFIFXRLCCPAKNX-UHFFFAOYSA-N 50600560 CHEMBL5169521 Oxysterols receptor LXR-beta 1700 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600560&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168269668 482611412 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490170 CC(C)(C)[Si](C)(C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C15H20F6OSi/c1-12(2,3)23(4,5)11-8-6-10(7-9-11)13(22,14(16,17)18)15(19,20)21/h6-9,22H,1-5H3 CQDIVDMHKRLIRW-UHFFFAOYSA-N 50600561 CHEMBL5184494 Oxysterols receptor LXR-beta 650 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600561&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168282164 482611413 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490171 C[Si](C)(C1CCCCC1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H22F6OSi/c1-25(2,13-6-4-3-5-7-13)14-10-8-12(9-11-14)15(24,16(18,19)20)17(21,22)23/h8-11,13,24H,3-7H2,1-2H3 QQDKQVVLCMCRDB-UHFFFAOYSA-N 50600562 CHEMBL5184224 Oxysterols receptor LXR-beta 740 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600562&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168278822 482611414 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490172 C[Si](C)(c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C17H16F6OSi/c1-25(2,13-6-4-3-5-7-13)14-10-8-12(9-11-14)15(24,16(18,19)20)17(21,22)23/h3-11,24H,1-2H3 SCWDCCUXDJMNMM-UHFFFAOYSA-N 50600563 CHEMBL5195024 Oxysterols receptor LXR-beta 740 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600563&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168285849 482611415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490173 C[Si](C)(Cc1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C18H18F6OSi/c1-26(2,12-13-6-4-3-5-7-13)15-10-8-14(9-11-15)16(25,17(19,20)21)18(22,23)24/h3-11,25H,12H2,1-2H3 UHDBFZNWFWMGJD-UHFFFAOYSA-N 50600564 CHEMBL5187585 Oxysterols receptor LXR-beta 720 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600564&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168281096 482611416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490174 C[Si](C)(C)[Si](C)(C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C14H20F6OSi2/c1-22(2,3)23(4,5)11-8-6-10(7-9-11)12(21,13(15,16)17)14(18,19)20/h6-9,21H,1-5H3 PRXLCVLOGCQYDQ-UHFFFAOYSA-N 50600565 CHEMBL5188694 Oxysterols receptor LXR-beta 510 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600565&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168282776 482611417 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490175 CC[Si](C)(CC)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C14H18F6OSi/c1-4-22(3,5-2)11-8-6-10(7-9-11)12(21,13(15,16)17)14(18,19)20/h6-9,21H,4-5H2,1-3H3 QJWKWXCDGBCZSA-UHFFFAOYSA-N 50600566 CHEMBL5179248 Oxysterols receptor LXR-beta 690 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600566&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168271253 482611418 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490176 C[Si](C)(CCO)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C13H16F6O2Si/c1-22(2,8-7-20)10-5-3-9(4-6-10)11(21,12(14,15)16)13(17,18)19/h3-6,20-21H,7-8H2,1-2H3 NHYBMDOXHHUKTA-UHFFFAOYSA-N 50600567 CHEMBL5196110 Oxysterols receptor LXR-beta 1730 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600567&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168288068 482611419 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490177 CC(O)[Si](C)(C)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C13H16F6O2Si/c1-8(20)22(2,3)10-6-4-9(5-7-10)11(21,12(14,15)16)13(17,18)19/h4-8,20-21H,1-3H3 JLYCWINNCSIANB-UHFFFAOYSA-N 50600568 CHEMBL5192368 Oxysterols receptor LXR-beta 3340 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600568&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168284921 482611420 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490178 C[Si](C)(CCCO)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C14H18F6O2Si/c1-23(2,9-3-8-21)11-6-4-10(5-7-11)12(22,13(15,16)17)14(18,19)20/h4-7,21-22H,3,8-9H2,1-2H3 KNLLYRSQGRCDFQ-UHFFFAOYSA-N 50600569 CHEMBL5198099 Oxysterols receptor LXR-beta 4030 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600569&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168289062 482611421 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51490179 C[Si](O)(c1ccccc1)c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F InChI=1S/C16H14F6O2Si/c1-25(24,12-5-3-2-4-6-12)13-9-7-11(8-10-13)14(23,15(17,18)19)16(20,21)22/h2-10,23-24H,1H3 RSSFATWHTCJONS-UHFFFAOYSA-N 50600570 CHEMBL5195914 Oxysterols receptor LXR-beta 5030 ChEMBL 10.7270/Q2183BKK 35576658 Namba, N; Noguchi-Yachide, T; Matsumoto, Y; Hashimoto, Y; Fujii, S Tokyo Medical and Dental University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50600570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50600570&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168289966 482611422 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341669 CCN(C)C(=O)OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H43NO3/c1-6-27(5)24(29)30-16-17(2)21-9-10-22-20-8-7-18-15-19(28)11-13-25(18,3)23(20)12-14-26(21,22)4/h7,17,19-23,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,25+,26-/m1/s1 QXTFHOMFBXXSCH-LXVLQKCJSA-N 630053 US20230340011, Example 352. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630053&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312791 485657717 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341671 CCn1c(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)n[nH]c1=S 630054 4-ethyl-5-((R)-3-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)butyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione::US20230340011, Example 353. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630054&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312907 485657718 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341673 C[C@H](CCC(=O)N1CCNS(=O)(=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H46N2O4S/c1-19(4-9-26(32)30-15-14-29-35(33,34)17-16-30)23-7-8-24-22-6-5-20-18-21(31)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,29,31H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 VLRGPTBHAOXONO-JDTILAPWSA-N 630055 US20230340011, Example 354. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630055&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312445 485657719 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341675 C[C@H](CCC(=O)N1CCCS(=O)(=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO4S/c1-20(5-10-27(32)30-15-4-17-35(33,34)18-16-30)24-8-9-25-23-7-6-21-19-22(31)11-13-28(21,2)26(23)12-14-29(24,25)3/h6,20,22-26,31H,4-5,7-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 HGKSMCLNMGQMKN-OHPSOFBHSA-N 630056 US20230340011, Example 355. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630056&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312747 485657720 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341677 C[C@H](CCC(=O)N1CCS(=O)(=O)C(C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO4S/c1-19(5-10-27(32)30-15-16-35(33,34)20(2)18-30)24-8-9-25-23-7-6-21-17-22(31)11-13-28(21,3)26(23)12-14-29(24,25)4/h6,19-20,22-26,31H,5,7-18H2,1-4H3/t19-,20?,22+,23+,24-,25+,26+,28+,29-/m1/s1 PEURSKGSZSHOAE-DRUFDEODSA-N 630057 US20230340011, Example 356. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630057&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311968 485657721 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341679 C[C@H](CCC(=O)N1CCS(=O)(=O)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H43NO4S/c1-18(4-9-25(30)28-14-15-33(31,32)17-28)22-7-8-23-21-6-5-19-16-20(29)10-12-26(19,2)24(21)11-13-27(22,23)3/h5,18,20-24,29H,4,6-17H2,1-3H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 KCUNCIQSEILFOK-ZHHJOTBYSA-N 630058 US20230340011, Example 357. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630058&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312196 485657722 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341681 C[C@H](CCC(=O)N1CCN(CC1)S(=O)(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H51N3O4S/c1-21(6-11-28(35)32-16-18-33(19-17-32)38(36,37)31(4)5)25-9-10-26-24-8-7-22-20-23(34)12-14-29(22,2)27(24)13-15-30(25,26)3/h7,21,23-27,34H,6,8-20H2,1-5H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 WDCUUICYEGGSSY-NXUCFJMCSA-N 630059 US20230340011, Example 358. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630059&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312485 485657723 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341683 C[C@H](CCC(=O)N1CCN(CC1)S(N)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47N3O4S/c1-19(4-9-26(33)30-14-16-31(17-15-30)36(29,34)35)23-7-8-24-22-6-5-20-18-21(32)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,32H,4,6-18H2,1-3H3,(H2,29,34,35)/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 ZZNGANJGMISMTK-JDTILAPWSA-N 630060 US20230340011, Example 359. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630060&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312649 485657724 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341685 COC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N2O4/c1-20(5-10-27(34)31-15-17-32(18-16-31)28(35)36-4)24-8-9-25-23-7-6-21-19-22(33)11-13-29(21,2)26(23)12-14-30(24,25)3/h6,20,22-26,33H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 NTZFOYIXBLJUIQ-RFWRZFGQSA-N 630061 US20230340011, Example 360. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630061&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312785 485657725 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341687 C[C@H](CCC(=O)N1CCN(C)C(=O)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H46N2O3/c1-19(5-10-26(33)31-16-15-30(4)27(34)18-31)23-8-9-24-22-7-6-20-17-21(32)11-13-28(20,2)25(22)12-14-29(23,24)3/h6,19,21-25,32H,5,7-18H2,1-4H3/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 DHJGQIXCCQPSFZ-YIZNBMETSA-N 630062 US20230340011, Example 361. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630062&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312731 485657726 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341689 C[C@H](CCC(=O)N1CCNC(=O)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H44N2O3/c1-18(4-9-26(33)30-15-14-29-25(32)17-30)22-7-8-23-21-6-5-19-16-20(31)10-12-27(19,2)24(21)11-13-28(22,23)3/h5,18,20-24,31H,4,6-17H2,1-3H3,(H,29,32)/t18-,20+,21+,22-,23+,24+,27+,28-/m1/s1 UFFRTCAUIWEZJQ-KVBJCFKZSA-N 630063 US20230340011, Example 362. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630063&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312067 485657727 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341691 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1nnnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N6O3/c1-20(5-10-27(39)36-15-17-37(18-16-36)29(40)28-32-33-34-35(28)4)24-8-9-25-23-7-6-21-19-22(38)11-13-30(21,2)26(23)12-14-31(24,25)3/h6,20,22-26,38H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,30+,31-/m1/s1 DCRSFTQJVNKEQA-HCJGDWAISA-N 630064 US20230340011, Example 363. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630064&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311885 485657728 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341693 CNC(=O)NCC1(C)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55N3O3/c1-22(6-11-29(38)36-18-16-31(2,17-19-36)21-35-30(39)34-5)26-9-10-27-25-8-7-23-20-24(37)12-14-32(23,3)28(25)13-15-33(26,27)4/h7,22,24-28,37H,6,8-21H2,1-5H3,(H2,34,35,39)/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 VUWMFFIXARHUTC-WKFLPMMISA-N 630065 US20230340011, Example 364. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630065&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311969 485657729 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341695 C[C@H](CCC(=O)N1CCC(C)(CNC(=O)C(C)(C)O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H58N2O4/c1-23(7-12-30(39)37-19-17-33(4,18-20-37)22-36-31(40)32(2,3)41)27-10-11-28-26-9-8-24-21-25(38)13-15-34(24,5)29(26)14-16-35(27,28)6/h8,23,25-29,38,41H,7,9-22H2,1-6H3,(H,36,40)/t23-,25+,26+,27-,28+,29+,34+,35-/m1/s1 UXDPYGHUATZWDP-PLOQSNKASA-N 630066 US20230340011, Example 365. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630066&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311962 485657730 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341698 C[C@H](CCC(=O)N1CCC(C)(CNS(C)(=O)=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H54N2O4S/c1-22(6-11-29(36)34-18-16-30(2,17-19-34)21-33-39(5,37)38)26-9-10-27-25-8-7-23-20-24(35)12-14-31(23,3)28(25)13-15-32(26,27)4/h7,22,24-28,33,35H,6,8-21H2,1-5H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 IBKMKUMDBIOOHR-XJGPRUKRSA-N 630068 US20230340011, Example 367. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630068&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312564 485657732 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341701 C[C@H](CCc1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H43NO/c1-20(8-10-22-7-5-6-18-30-22)24-12-13-25-23-11-9-21-19-27(2,31)16-17-28(21,3)26(23)14-15-29(24,25)4/h5-7,9,18,20,23-26,31H,8,10-17,19H2,1-4H3/t20-,23+,24-,25+,26+,27+,28+,29-/m1/s1 SDJJRZOSTAPLIM-HZEDMITCSA-N 630070 US20230340011, Example 369. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630070&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312912 485657734 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341704 CCC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53NO3/c1-6-32(36)17-19-33(20-18-32)28(34)12-7-22(2)25-10-11-26-24-9-8-23-21-29(3,35)15-16-30(23,4)27(24)13-14-31(25,26)5/h8,22,24-27,35-36H,6-7,9-21H2,1-5H3/t22-,24+,25-,26+,27+,29+,30+,31-/m1/s1 PKIRPTWVIDGVIA-LKMYJKNRSA-N 630072 US20230340011, Example 371. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630072&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312251 485657736 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341706 C[C@H](CCC(=O)N1CC2(C1)CC(C)(CO)C2)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51NO3/c1-21(5-10-28(36)33-18-32(19-33)16-29(2,17-32)20-34)25-8-9-26-24-7-6-22-15-23(35)11-13-30(22,3)27(24)12-14-31(25,26)4/h6,21,23-27,34-35H,5,7-20H2,1-4H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 NXARUEHLRWODTE-MIXBDBMTSA-N 630073 US20230340011, Example 372. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630073&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312312 485657737 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341708 C[C@H](CCC(=O)N1CC[C@](C)(CO)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(5-10-27(34)31-16-15-28(2,18-31)19-32)24-8-9-25-23-7-6-21-17-22(33)11-13-29(21,3)26(23)12-14-30(24,25)4/h6,20,22-26,32-33H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,28+,29+,30-/m1/s1 SUIGYROTYDUZRD-ARFMSILVSA-N 630074 US20230340011, Example 374. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630074&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312666 485657738 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341710 C[C@H](CCC(=O)N1CCCC(C)(CO)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53NO3/c1-22(6-11-29(36)33-18-5-14-30(2,21-34)17-19-33)26-9-10-27-25-8-7-23-20-24(35)12-15-31(23,3)28(25)13-16-32(26,27)4/h7,22,24-28,34-35H,5-6,8-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,30?,31+,32-/m1/s1 CGJYPCUAMQMUMR-MSJAMATOSA-N 630075 US20230340011, Example 375. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630075&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311859 485657739 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341712 C[C@H](CCC(=O)N1CCC(CO)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(4-9-28(34)31-16-12-21(19-32)13-17-31)25-7-8-26-24-6-5-22-18-23(33)10-14-29(22,2)27(24)11-15-30(25,26)3/h5,20-21,23-27,32-33H,4,6-19H2,1-3H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 HUMBUMHTRIKMPI-CMZGQUJUSA-N 630076 US20230340011, Example 376. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630076&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312199 485657740 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341714 CC(O)C1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51NO3/c1-20(5-10-29(35)32-17-13-22(14-18-32)21(2)33)26-8-9-27-25-7-6-23-19-24(34)11-15-30(23,3)28(25)12-16-31(26,27)4/h6,20-22,24-28,33-34H,5,7-19H2,1-4H3/t20-,21?,24+,25+,26-,27+,28+,30+,31-/m1/s1 GGYAYXDZATWEIK-ZSHOUEONSA-N 630077 US20230340011, Example 377. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630077&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312558 485657741 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341716 C[C@H](CCC(=O)N1CCC(CC1)C(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53NO3/c1-21(6-11-29(35)33-18-14-22(15-19-33)30(2,3)36)26-9-10-27-25-8-7-23-20-24(34)12-16-31(23,4)28(25)13-17-32(26,27)5/h7,21-22,24-28,34,36H,6,8-20H2,1-5H3/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 RXLSXIFHMUXAFL-XKQUNUCNSA-N 630078 US20230340011, Example 378. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630078&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312874 485657742 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341718 C[C@H](Oc1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H37NO2/c1-17(29-20-10-14-27-15-11-20)22-6-7-23-21-5-4-18-16-19(28)8-12-25(18,2)24(21)9-13-26(22,23)3/h4,10-11,14-15,17,19,21-24,28H,5-9,12-13,16H2,1-3H3/t17-,19-,21-,22+,23-,24-,25-,26+/m0/s1 VDXLVOKEEUEOCA-BEKKXJRNSA-N 630079 US20230340011, Example 379. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630079&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311921 485657743 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341720 C[C@H](Oc1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H37NO2/c1-17(29-20-5-4-14-27-16-20)22-8-9-23-21-7-6-18-15-19(28)10-12-25(18,2)24(21)11-13-26(22,23)3/h4-6,14,16-17,19,21-24,28H,7-13,15H2,1-3H3/t17-,19-,21-,22+,23-,24-,25-,26+/m0/s1 UDXLMJSGVINJRZ-BEKKXJRNSA-N 630080 US20230340011, Example 380. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630080&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312530 485657744 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341723 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ncnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N5O3/c1-21(5-10-28(39)36-15-17-37(18-16-36)30(40)29-33-20-34-35(29)4)25-8-9-26-24-7-6-22-19-23(38)11-13-31(22,2)27(24)12-14-32(25,26)3/h6,20-21,23-27,38H,5,7-19H2,1-4H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 UXMSHHWIAKGKIF-GTORSBDHSA-N 630082 US20230340011, Example 382. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630082&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311948 485657746 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341725 C[C@H](CCC(=O)N1CCC(O)(CC1)C1CCCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H57NO3/c1-24(9-14-32(38)36-21-19-35(39,20-22-36)25-7-5-4-6-8-25)29-12-13-30-28-11-10-26-23-27(37)15-17-33(26,2)31(28)16-18-34(29,30)3/h10,24-25,27-31,37,39H,4-9,11-23H2,1-3H3/t24-,27+,28+,29-,30+,31+,33+,34-/m1/s1 HETHIVRKYVLPDA-LLHZKFLPSA-N 630083 US20230340011, Example 383. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630083&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312181 485657747 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341727 C[C@H](CCC(=O)N1CCC(O)(CC1)C#N)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H46N2O3/c1-20(4-9-27(34)32-16-14-30(35,19-31)15-17-32)24-7-8-25-23-6-5-21-18-22(33)10-12-28(21,2)26(23)11-13-29(24,25)3/h5,20,22-26,33,35H,4,6-18H2,1-3H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 JKPRVFVLDDBCSV-OHPSOFBHSA-N 630084 US20230340011, Example 384. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630084&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312025 485657748 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341729 CCC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-5-28(35)32-16-18-33(19-17-32)29(36)11-6-21(2)25-9-10-26-24-8-7-22-20-23(34)12-14-30(22,3)27(24)13-15-31(25,26)4/h7,21,23-27,34H,5-6,8-20H2,1-4H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 WOIVXAQFWVREQZ-MIXBDBMTSA-N 630085 US20230340011, Example 385. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630085&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311857 485657749 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341731 CC(C)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-21(2)30(37)34-18-16-33(17-19-34)29(36)11-6-22(3)26-9-10-27-25-8-7-23-20-24(35)12-14-31(23,4)28(25)13-15-32(26,27)5/h7,21-22,24-28,35H,6,8-20H2,1-5H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 FCPBOBNQKUTZSE-XJGPRUKRSA-N 630016 US20230340011, Example 315.::US20230340011, Example 386. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630016&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312293 485657680 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341733 C[C@H](CCC(=O)N1CCN(CC1)C(=O)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O3/c1-21(4-11-29(36)33-16-18-34(19-17-33)30(37)22-5-6-22)26-9-10-27-25-8-7-23-20-24(35)12-14-31(23,2)28(25)13-15-32(26,27)3/h7,21-22,24-28,35H,4-6,8-20H2,1-3H3/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 VEGJZBOTMLUQOF-XKQUNUCNSA-N 630015 US20230340011, Example 314.::US20230340011, Example 387. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312070 485657679 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341735 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H49N3O3/c1-23(6-11-31(39)36-17-19-37(20-18-36)32(40)24-5-4-16-35-22-24)28-9-10-29-27-8-7-25-21-26(38)12-14-33(25,2)30(27)13-15-34(28,29)3/h4-5,7,16,22-23,26-30,38H,6,8-15,17-21H2,1-3H3/t23-,26+,27+,28-,29+,30+,33+,34-/m1/s1 WSSPERYQWHNBTM-WACGHZNISA-N 630014 US20230340011, Example 313.::US20230340011, Example 388. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312741 485657678 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341737 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ccnnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H48N4O3/c1-22(4-9-30(39)36-16-18-37(19-17-36)31(40)23-12-15-34-35-21-23)27-7-8-28-26-6-5-24-20-25(38)10-13-32(24,2)29(26)11-14-33(27,28)3/h5,12,15,21-22,25-29,38H,4,6-11,13-14,16-20H2,1-3H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 TZUFFUTYMSFLIM-VEQXFWRMSA-N 630013 US20230340011, Example 312.::US20230340011, Example 389. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312569 485657677 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341739 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ccns1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H47N3O3S/c1-21(4-9-29(37)34-16-18-35(19-17-34)30(38)28-12-15-33-39-28)25-7-8-26-24-6-5-22-20-23(36)10-13-31(22,2)27(24)11-14-32(25,26)3/h5,12,15,21,23-27,36H,4,6-11,13-14,16-20H2,1-3H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 MDLMAXAHXWCDIA-GTORSBDHSA-N 630012 US20230340011, Example 311.::US20230340011, Example 390. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312643 485657676 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341741 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cn[nH]c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 630011 US20230340011, Example 310.::US20230340011, Example 391. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312250 485657675 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341743 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)36-15-17-37(18-16-36)31(40)23-20-34-35(4)21-23)27-8-9-28-26-7-6-24-19-25(38)11-13-32(24,2)29(26)12-14-33(27,28)3/h6,20-22,25-29,38H,5,7-19H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 DQGMTMJCVJHZGV-VEQXFWRMSA-N 630010 US20230340011, Example 309.::US20230340011, Example 392.::US20230340011, Example 565. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312775 485657674 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341745 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cn(C)nn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N5O3/c1-21(5-10-29(39)36-15-17-37(18-16-36)30(40)28-20-35(4)34-33-28)25-8-9-26-24-7-6-22-19-23(38)11-13-31(22,2)27(24)12-14-32(25,26)3/h6,20-21,23-27,38H,5,7-19H2,1-4H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 ZEIGNTCDPVULKY-GTORSBDHSA-N 630009 US20230340011, Example 308.::US20230340011, Example 393. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630009&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312215 485657673 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341747 C[C@H](CCC(=O)N1CCN(CC1)c1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O2/c1-23(7-12-31(38)36-20-18-35(19-21-36)30-6-4-5-17-34-30)27-10-11-28-26-9-8-24-22-25(37)13-15-32(24,2)29(26)14-16-33(27,28)3/h4-6,8,17,23,25-29,37H,7,9-16,18-22H2,1-3H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 YPDZZGTWIGIMJD-ACBDEFBISA-N 630008 US20230340011, Example 307.::US20230340011, Example 394. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630008&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312448 485657672 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341749 C[C@H](CCC(=O)N1CCN(CC1)c1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O2/c1-23(6-11-31(38)36-19-17-35(18-20-36)25-5-4-16-34-22-25)28-9-10-29-27-8-7-24-21-26(37)12-14-32(24,2)30(27)13-15-33(28,29)3/h4-5,7,16,22-23,26-30,37H,6,8-15,17-21H2,1-3H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 FYWJALJKZHBWQH-ZWWVIQJBSA-N 630007 US20230340011, Example 306.::US20230340011, Example 395. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630007&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312697 485657671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341751 C[C@H](CCC(=O)N1CCN(CC1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O2/c1-23(4-9-31(38)36-20-18-35(19-21-36)25-12-16-34-17-13-25)28-7-8-29-27-6-5-24-22-26(37)10-14-32(24,2)30(27)11-15-33(28,29)3/h5,12-13,16-17,23,26-30,37H,4,6-11,14-15,18-22H2,1-3H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 KNXWBYYFPWKACB-ZWWVIQJBSA-N 630096 US20230340011, Example 396. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630096&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312518 485657750 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341753 C[C@H](CCC(=O)N1CCN(CC1)c1ncccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(5-10-29(38)35-17-19-36(20-18-35)30-33-15-4-16-34-30)26-8-9-27-25-7-6-23-21-24(37)11-13-31(23,2)28(25)12-14-32(26,27)3/h4,6,15-16,22,24-28,37H,5,7-14,17-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 USGBYQDDDUHZEI-XJGPRUKRSA-N 630097 US20230340011, Example 397. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630097&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312573 485657751 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341755 C[C@H](CCC(=O)N1CCN(CC1)c1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(4-9-30(38)36-18-16-35(17-19-36)29-21-33-14-15-34-29)26-7-8-27-25-6-5-23-20-24(37)10-12-31(23,2)28(25)11-13-32(26,27)3/h5,14-15,21-22,24-28,37H,4,6-13,16-20H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 USTRWUCCQNOIPP-XJGPRUKRSA-N 630005 US20230340011, Example 304.::US20230340011, Example 305.::US20230340011, Example 398. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630005&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311957 485657670 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341757 C[C@H](CCC(=O)N1CCN(CC1)c1cccnn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(6-11-30(38)36-19-17-35(18-20-36)29-5-4-16-33-34-29)26-9-10-27-25-8-7-23-21-24(37)12-14-31(23,2)28(25)13-15-32(26,27)3/h4-5,7,16,22,24-28,37H,6,8-15,17-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 HFQNLBNQTGYVQZ-XJGPRUKRSA-N 630004 US20230340011, Example 303.::US20230340011, Example 399. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630004&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312633 485657669 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341759 C[C@H](CCC(=O)N1CCN(CC1)c1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(4-9-30(38)36-18-16-35(17-19-36)29-12-15-33-21-34-29)26-7-8-27-25-6-5-23-20-24(37)10-13-31(23,2)28(25)11-14-32(26,27)3/h5,12,15,21-22,24-28,37H,4,6-11,13-14,16-20H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 FODFXKVWAKEVBZ-XJGPRUKRSA-N 630100 US20230340011, Example 400. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630100&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312484 485657752 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341761 C[C@H](CCC(=O)N1CCC(CC1)Oc1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O3/c1-23(4-9-32(38)36-20-14-27(15-21-36)39-26-12-18-35-19-13-26)29-7-8-30-28-6-5-24-22-25(37)10-16-33(24,2)31(28)11-17-34(29,30)3/h5,12-13,18-19,23,25,27-31,37H,4,6-11,14-17,20-22H2,1-3H3/t23-,25+,28+,29-,30+,31+,33+,34-/m1/s1 SWEUQVPZTGVSBU-HJIUKPPKSA-N 630002 US20230340011, Example 301.::US20230340011, Example 401. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630002&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311917 485657667 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341763 CO[C@H]1CCCN(C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(7-12-28(33)31-17-5-6-23(19-31)34-4)25-10-11-26-24-9-8-21-18-22(32)13-15-29(21,2)27(24)14-16-30(25,26)3/h8,20,22-27,32H,5-7,9-19H2,1-4H3/t20-,22+,23+,24+,25-,26+,27+,29+,30-/m1/s1 AJPPENWWEOYGLC-DHXMEVIDSA-N 630001 US20230340011, Example 300.::US20230340011, Example 402. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630001&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312853 485657666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341765 C[C@H](CCC(=O)N(C)[C@@H]1CC[C@@H](CC1)N(C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-32(39)36(6)26-11-9-25(10-12-26)35(5)23(2)37)29-14-15-30-28-13-8-24-21-27(38)17-19-33(24,3)31(28)18-20-34(29,30)4/h8,22,25-31,38H,7,9-21H2,1-6H3/t22-,25-,26+,27+,28+,29-,30+,31+,33+,34-/m1/s1 GMNIHTMJHRCHEM-FKSYZIAMSA-N 630103 US20230340011, Example 403. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630103&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312452 485657753 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341767 C[C@H](CCC(=O)N(C)[C@H]1CC[C@@H](CC1)N(C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-32(39)36(6)26-11-9-25(10-12-26)35(5)23(2)37)29-14-15-30-28-13-8-24-21-27(38)17-19-33(24,3)31(28)18-20-34(29,30)4/h8,22,25-31,38H,7,9-21H2,1-6H3/t22-,25-,26-,27+,28+,29-,30+,31+,33+,34-/m1/s1 GMNIHTMJHRCHEM-ZHUPGQSKSA-N 630104 US20230340011, Example 404. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630104&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312452 485657754 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341769 C[C@H](CCC(=O)N(C)[C@H]1CC[C@H](CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-31(38)36(6)25-11-8-23(9-12-25)32(39)35(4)5)28-14-15-29-27-13-10-24-21-26(37)17-19-33(24,2)30(27)18-20-34(28,29)3/h10,22-23,25-30,37H,7-9,11-21H2,1-6H3/t22-,23-,25+,26+,27+,28-,29+,30+,33+,34-/m1/s1 RVZOTPVQYDMLNP-ZAPRWDPSSA-N 630105 US20230340011, Example 405. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630105&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311882 485657755 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341771 C[C@H](CCC(=O)N(C)[C@H]1CC[C@@H](CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-31(38)36(6)25-11-8-23(9-12-25)32(39)35(4)5)28-14-15-29-27-13-10-24-21-26(37)17-19-33(24,2)30(27)18-20-34(28,29)3/h10,22-23,25-30,37H,7-9,11-21H2,1-6H3/t22-,23-,25-,26+,27+,28-,29+,30+,33+,34-/m1/s1 RVZOTPVQYDMLNP-HLPOEUGRSA-N 630106 US20230340011, Example 406. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630106&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311882 485657756 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341773 C[C@H](CCC(=O)N(C)C1CCN(CC1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-21(6-11-30(37)33(5)24-14-18-34(19-15-24)22(2)35)27-9-10-28-26-8-7-23-20-25(36)12-16-31(23,3)29(26)13-17-32(27,28)4/h7,21,24-29,36H,6,8-20H2,1-5H3/t21-,25+,26+,27-,28+,29+,31+,32-/m1/s1 XUQGHHPHSBZJPL-KNLNLFKVSA-N 629996 US20230340011, Example 295.::US20230340011, Example 407. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629996&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312665 485657661 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341776 C[C@H](CCC(=O)N(C)CCc1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N2O2/c1-22(8-13-30(36)34(4)20-16-24-7-5-6-19-33-24)27-11-12-28-26-10-9-23-21-25(35)14-17-31(23,2)29(26)15-18-32(27,28)3/h5-7,9,19,22,25-29,35H,8,10-18,20-21H2,1-4H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 MALABKVRPVMDNF-NWKCFVCZSA-N 629994 US20230340011, Example 293.::US20230340011, Example 409. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629994&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312614 485657659 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341778 C[C@H](CCC(=O)N1CC2(C1)OCCN2C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N2O4/c1-20(5-10-28(36)32-18-31(19-32)33(21(2)34)15-16-37-31)25-8-9-26-24-7-6-22-17-23(35)11-13-29(22,3)27(24)12-14-30(25,26)4/h6,20,23-27,35H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 FZFLNAMWBWHYPM-CMZGQUJUSA-N 630110 US20230340011, Example 410. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630110&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169257259 485657757 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341780 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1nc(C)no1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O4/c1-20(5-10-28(38)35-15-17-36(18-16-35)30(39)29-33-21(2)34-40-29)25-8-9-26-24-7-6-22-19-23(37)11-13-31(22,3)27(24)12-14-32(25,26)4/h6,20,23-27,37H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,31+,32-/m1/s1 BHQQMEQOZBLXLK-LDQJSCHESA-N 629993 US20230340011, Example 292.::US20230340011, Example 411. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312177 485657658 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341782 CNS(=O)(=O)C1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H50N2O4S/c1-20(5-10-28(34)32-17-13-23(14-18-32)37(35,36)31-4)25-8-9-26-24-7-6-21-19-22(33)11-15-29(21,2)27(24)12-16-30(25,26)3/h6,20,22-27,31,33H,5,7-19H2,1-4H3/t20-,22+,24+,25-,26+,27+,29+,30-/m1/s1 FWNUYAQNOAEZGO-UZKJJXDZSA-N 629992 US20230340011, Example 291.::US20230340011, Example 412. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312459 485657657 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341784 C[C@H](CCC(=O)N1CCC(CC1)S(=O)(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O4S/c1-21(6-11-29(35)33-18-14-24(15-19-33)38(36,37)32(4)5)26-9-10-27-25-8-7-22-20-23(34)12-16-30(22,2)28(25)13-17-31(26,27)3/h7,21,23-28,34H,6,8-20H2,1-5H3/t21-,23+,25+,26-,27+,28+,30+,31-/m1/s1 AZAMCAAZSQKHQX-KHGYUHDZSA-N 629991 US20230340011, Example 290.::US20230340011, Example 413. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629991&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312548 485657656 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341786 C[C@H](CCC(=O)N1CCC(CC1)NS(C)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H50N2O4S/c1-20(5-10-28(34)32-17-13-22(14-18-32)31-37(4,35)36)25-8-9-26-24-7-6-21-19-23(33)11-15-29(21,2)27(24)12-16-30(25,26)3/h6,20,22-27,31,33H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 VTBDLXZDWCAUPB-CMZGQUJUSA-N 630114 US20230340011, Example 414. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630114&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312310 485657758 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341788 C[C@H](CCC(=O)N1CCC(CC1)N(C)S(C)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O4S/c1-21(6-11-29(35)33-18-14-23(15-19-33)32(4)38(5,36)37)26-9-10-27-25-8-7-22-20-24(34)12-16-30(22,2)28(25)13-17-31(26,27)3/h7,21,23-28,34H,6,8-20H2,1-5H3/t21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 BIXNIUQKIIVIJX-ANSWHRQLSA-N 629990 US20230340011, Example 289.::US20230340011, Example 415. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629990&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312605 485657655 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341790 C[C@H](CCC(=O)N1CCC(CC1)N(C)C(=O)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H53N3O3/c1-24(5-10-33(41)39-21-15-27(16-22-39)38(4)34(42)25-13-19-37-20-14-25)30-8-9-31-29-7-6-26-23-28(40)11-17-35(26,2)32(29)12-18-36(30,31)3/h6,13-14,19-20,24,27-32,40H,5,7-12,15-18,21-23H2,1-4H3/t24-,28+,29+,30-,31+,32+,35+,36-/m1/s1 RQWPRIOZCPAJJG-HKMDHWLPSA-N 629989 US20230340011, Example 288.::US20230340011, Example 416. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629989&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312620 485657654 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341792 C[C@H](CCC(=O)N1CCC(CC1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O2/c1-23(4-9-32(38)36-20-14-25(15-21-36)24-12-18-35-19-13-24)29-7-8-30-28-6-5-26-22-27(37)10-16-33(26,2)31(28)11-17-34(29,30)3/h5,12-13,18-19,23,25,27-31,37H,4,6-11,14-17,20-22H2,1-3H3/t23-,27+,28+,29-,30+,31+,33+,34-/m1/s1 RZZWGGCRGMCXCD-AESKLMAPSA-N 629988 US20230340011, Example 287.::US20230340011, Example 417. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629988&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312648 485657653 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341796 CC[C@]1(O)CC[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CC=C2C1)[C@H](C)CCC(=O)N1CCN(CC1)C(=O)OC InChI=1S/C32H52N2O4/c1-6-32(37)16-15-30(3)23(21-32)8-9-24-26-11-10-25(31(26,4)14-13-27(24)30)22(2)7-12-28(35)33-17-19-34(20-18-33)29(36)38-5/h8,22,24-27,37H,6-7,9-21H2,1-5H3/t22-,24+,25-,26+,27+,30+,31-,32+/m1/s1 JMIDLZLQUVTWFQ-YVPUZFGVSA-N 629985 US20230340011, Example 284.::US20230340011, Example 420. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629985&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312065 485657650 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341798 COC(=O)N1CCN(CC1)C(=O)CCC[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H46N2O4/c1-28-14-12-25-23(9-7-21-19-22(32)11-13-29(21,25)2)24(28)10-8-20(28)5-4-6-26(33)30-15-17-31(18-16-30)27(34)35-3/h7,20,22-25,32H,4-6,8-19H2,1-3H3/t20-,22-,23-,24-,25-,28+,29-/m0/s1 NIZMSDBCIKBAAK-AADPQPSGSA-N 629984 US20230340011, Example 283.::US20230340011, Example 421. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629984&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312615 485657649 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341800 CCOC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O4/c1-5-37-29(36)33-18-16-32(17-19-33)28(35)11-6-21(2)25-9-10-26-24-8-7-22-20-23(34)12-14-30(22,3)27(24)13-15-31(25,26)4/h7,21,23-27,34H,5-6,8-20H2,1-4H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 NBOHNTGQPDPLQJ-MIXBDBMTSA-N 629983 US20230340011, Example 282.::US20230340011, Example 422. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629983&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312654 485657648 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341802 C[C@H](CCC(=O)N1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H49N3O6/c1-23(4-13-32(40)36-18-20-37(21-19-36)33(41)44-27-8-6-25(7-9-27)38(42)43)29-11-12-30-28-10-5-24-22-26(39)14-16-34(24,2)31(28)15-17-35(29,30)3/h5-9,23,26,28-31,39H,4,10-22H2,1-3H3/t23-,26+,28+,29-,30+,31+,34+,35-/m1/s1 OAIDVWUIFDZVDV-CGZFNOTRSA-N 630123 US20230340011, Example 423. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630123&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311956 485657759 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341804 COCCOC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O5/c1-22(5-10-29(36)33-15-17-34(18-16-33)30(37)39-20-19-38-4)26-8-9-27-25-7-6-23-21-24(35)11-13-31(23,2)28(25)12-14-32(26,27)3/h6,22,24-28,35H,5,7-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 NMPIFQFHUSMKOP-XJGPRUKRSA-N 629981 US20230340011, Example 280.::US20230340011, Example 424. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629981&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312162 485657646 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341806 C[C@H](CCC(=O)N1CCN(CC1)C(=O)OC1COC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O5/c1-21(4-9-29(36)33-14-16-34(17-15-33)30(37)39-24-19-38-20-24)26-7-8-27-25-6-5-22-18-23(35)10-12-31(22,2)28(25)11-13-32(26,27)3/h5,21,23-28,35H,4,6-20H2,1-3H3/t21-,23+,25+,26-,27+,28+,31+,32-/m1/s1 WWHQPROZNSKGNO-UJWPGJPTSA-N 629980 US20230340011, Example 279.::US20230340011, Example 425. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629980&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312422 485657645 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341808 C[C@H](CCC(=O)N1CCN([C@H](C)C1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)32-16-17-33(22(3)34)21(2)19-32)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 FAZIJNUCDJRALL-CSEUGJBGSA-N 629979 US20230340011, Example 278.::US20230340011, Example 426. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629979&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312640 485657644 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341810 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)32-16-17-33(22(3)34)21(2)19-32)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21+,24+,25+,26-,27+,28+,30+,31-/m1/s1 FAZIJNUCDJRALL-BMYROFSPSA-N 629978 US20230340011, Example 277.::US20230340011, Example 427. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629978&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311852 485657643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341812 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)33-17-16-32(22(3)34)19-21(33)2)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21+,24+,25+,26-,27+,28+,30+,31-/m1/s1 JFBHEEOFHUHZGZ-BMYROFSPSA-N 630128 US20230340011, Example 428. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630128&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312011 485657760 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341814 C[C@H](CCC(=O)N1CCN(C[C@H]1C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)33-17-16-32(22(3)34)19-21(33)2)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 JFBHEEOFHUHZGZ-CSEUGJBGSA-N 630129 US20230340011, Example 429. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630129&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312186 485657761 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341816 C[C@H](Oc1cccnc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H39NO2/c1-17-25(6-5-15-28-17)30-18(2)22-9-10-23-21-8-7-19-16-20(29)11-13-26(19,3)24(21)12-14-27(22,23)4/h5-7,15,18,20-24,29H,8-14,16H2,1-4H3/t18-,20-,21-,22+,23-,24-,26-,27+/m0/s1 AUCGFEVTLJHDTO-CNXJXGGASA-N 629975 US20230340011, Example 274.::US20230340011, Example 430. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629975&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312807 485657640 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341056 CON(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H43NO3/c1-17(6-11-24(29)27(4)30-5)21-9-10-22-20-8-7-18-16-19(28)12-14-25(18,2)23(20)13-15-26(21,22)3/h7,17,19-23,28H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,25+,26-/m1/s1 COAOXNQSRNFNRV-LXVLQKCJSA-N 629707 US20230340011, Example 1. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629707&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 10502093 485657378 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341058 C[C@H](CCC(=O)N1CCNCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H46N2O2/c1-19(4-9-26(32)30-16-14-29-15-17-30)23-7-8-24-22-6-5-20-18-21(31)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,29,31H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 FTUQTPVFCFZEMI-JDTILAPWSA-N 629710 US20230340011, Example 2. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629710&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312247 485657381 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341060 C[C@H](CCC(=O)N1CCN(CC1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N2O3/c1-20(5-10-28(35)32-17-15-31(16-18-32)21(2)33)25-8-9-26-24-7-6-22-19-23(34)11-13-29(22,3)27(24)12-14-30(25,26)4/h6,20,23-27,34H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 MHKOPQOQWGNLCX-CMZGQUJUSA-N 629711 US20230340011, Example 3. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629711&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312021 485657382 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341062 C[C@H](CCC(=O)N1CCN(CC1)C(N)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47N3O3/c1-19(4-9-26(34)31-14-16-32(17-15-31)27(30)35)23-7-8-24-22-6-5-20-18-21(33)10-12-28(20,2)25(22)11-13-29(23,24)3/h5,19,21-25,33H,4,6-18H2,1-3H3,(H2,30,35)/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 ZHCXPTOHHFGATB-YIZNBMETSA-N 629712 US20230340011, Example 4. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629712&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311886 485657383 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341064 C[C@H](CCC(=O)N1CCC(C)(C)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51NO2/c1-21(6-11-28(34)32-18-16-29(2,3)17-19-32)25-9-10-26-24-8-7-22-20-23(33)12-14-30(22,4)27(24)13-15-31(25,26)5/h7,21,23-27,33H,6,8-20H2,1-5H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 OPRLDLZWIBGJBK-MIXBDBMTSA-N 629713 US20230340011, Example 5. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629713&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 146180814 485657384 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341066 C[C@H](CCC(=O)N1CCC(C)(O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(5-10-27(33)31-17-15-28(2,34)16-18-31)24-8-9-25-23-7-6-21-19-22(32)11-13-29(21,3)26(23)12-14-30(24,25)4/h6,20,22-26,32,34H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 YNKCRJSHIPVWCB-RFWRZFGQSA-N 629714 US20230340011, Example 6. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629714&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312703 485657385 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341068 C[C@H](CCC(=O)N1CCOCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3/c1-19(4-9-26(31)29-14-16-32-17-15-29)23-7-8-24-22-6-5-20-18-21(30)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,30H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 OXRHDIXSNOWVQD-JDTILAPWSA-N 629715 US20230340011, Example 7. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629715&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 168232631 485657386 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341070 C[C@H](CCC(=O)N1CCSCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO2S/c1-19(4-9-26(31)29-14-16-32-17-15-29)23-7-8-24-22-6-5-20-18-21(30)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,30H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 UYXAJSBQPMWZMX-JDTILAPWSA-N 629716 US20230340011, Example 8. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629716&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312049 485657387 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341072 C[C@H](CCC(=O)N1CCS(=O)(=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO4S/c1-19(4-9-26(31)29-14-16-34(32,33)17-15-29)23-7-8-24-22-6-5-20-18-21(30)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,30H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 SSRIXNSQPXIKPV-JDTILAPWSA-N 629717 US20230340011, Example 9. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629717&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311999 485657388 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341074 CCON(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO3/c1-6-31-28(5)25(30)12-7-18(2)22-10-11-23-21-9-8-19-17-20(29)13-15-26(19,3)24(21)14-16-27(22,23)4/h8,18,20-24,29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 MTPMZVFOMVXGMD-ZHHJOTBYSA-N 629718 US20230340011, Example 10.::US20230340011, Example 12. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629718&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312522 485657389 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341075 CCN(OC)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO3/c1-6-28(31-5)25(30)12-7-18(2)22-10-11-23-21-9-8-19-17-20(29)13-15-26(19,3)24(21)14-16-27(22,23)4/h8,18,20-24,29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 PSGNYCLHQYFFNY-ZHHJOTBYSA-N 629719 US20230340011, Example 11. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629719&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312902 485657390 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341076 CCON(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO3/c1-6-31-28(5)25(30)12-7-18(2)22-10-11-23-21-9-8-19-17-20(29)13-15-26(19,3)24(21)14-16-27(22,23)4/h8,18,20-24,29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 MTPMZVFOMVXGMD-ZHHJOTBYSA-N 629718 US20230340011, Example 10.::US20230340011, Example 12. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629718&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312522 485657389 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341078 CCCN(OC)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO3/c1-6-17-29(32-5)26(31)12-7-19(2)23-10-11-24-22-9-8-20-18-21(30)13-15-27(20,3)25(22)14-16-28(23,24)4/h8,19,21-25,30H,6-7,9-18H2,1-5H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 NRIIKQNJMACHPJ-JDTILAPWSA-N 629721 US20230340011, Example 13. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629721&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312755 485657391 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341080 CC(C)ON(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO3/c1-18(2)32-29(6)26(31)12-7-19(3)23-10-11-24-22-9-8-20-17-21(30)13-15-27(20,4)25(22)14-16-28(23,24)5/h8,18-19,21-25,30H,7,9-17H2,1-6H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 PPGXOSGTBYPKMA-JDTILAPWSA-N 629722 US20230340011, Example 14. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629722&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312020 485657392 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341081 CON(C(C)C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO3/c1-18(2)29(32-6)26(31)12-7-19(3)23-10-11-24-22-9-8-20-17-21(30)13-15-27(20,4)25(22)14-16-28(23,24)5/h8,18-19,21-25,30H,7,9-17H2,1-6H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 HKXDHIXFZPLPQK-JDTILAPWSA-N 629723 US20230340011, Example 15. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629723&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312112 485657393 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341082 CCCC[O](C)N(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H52NO3/c1-7-8-19-34(6)31(5)28(33)14-9-21(2)25-12-13-26-24-11-10-22-20-23(32)15-17-29(22,3)27(24)16-18-30(25,26)4/h10,21,23-27,32H,7-9,11-20H2,1-6H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 LNXIZQSIGVGZQY-NXUCFJMCSA-N 629724 US20230340011, Example 16. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629724&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169490209 485657394 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341083 CCCCN(OC)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H49NO3/c1-6-7-18-30(33-5)27(32)13-8-20(2)24-11-12-25-23-10-9-21-19-22(31)14-16-28(21,3)26(23)15-17-29(24,25)4/h9,20,22-26,31H,6-8,10-19H2,1-5H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 DERUBASVYKDRBY-OHPSOFBHSA-N 629725 US20230340011, Example 17. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629725&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312453 485657395 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341085 C[C@H](CCC(=O)N1CCS(=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3S/c1-19(4-9-26(31)29-14-16-33(32)17-15-29)23-7-8-24-22-6-5-20-18-21(30)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,30H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 IXZCXHVZJJWHLV-JDTILAPWSA-N 629726 US20230340011, Example 18. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629726&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312414 485657396 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341087 C[C@H](CC[C@](O)(C=C)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H41F3O2/c1-5-26(32,27(28,29)30)15-10-17(2)21-8-9-22-20-7-6-18-16-19(31)11-13-24(18,3)23(20)12-14-25(21,22)4/h5-6,17,19-23,31-32H,1,7-16H2,2-4H3/t17-,19+,20+,21-,22+,23+,24+,25-,26-/m1/s1 FCVFYAAJXKZBOX-UDPAUNONSA-N 629727 US20230340011, Example 19. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629727&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311894 485657397 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341089 C[C@H](CC[C@@](O)(C=C)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H41F3O2/c1-5-26(32,27(28,29)30)15-10-17(2)21-8-9-22-20-7-6-18-16-19(31)11-13-24(18,3)23(20)12-14-25(21,22)4/h5-6,17,19-23,31-32H,1,7-16H2,2-4H3/t17-,19+,20+,21-,22+,23+,24+,25-,26+/m1/s1 FCVFYAAJXKZBOX-MVBYKKPWSA-N 629728 US20230340011, Example 20. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629728&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311890 485657398 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341096 COCCON(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO4/c1-19(6-11-26(31)29(4)33-17-16-32-5)23-9-10-24-22-8-7-20-18-21(30)12-14-27(20,2)25(22)13-15-28(23,24)3/h7,19,21-25,30H,6,8-18H2,1-5H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 MSKWHDJTNHBSBJ-JDTILAPWSA-N 629735 US20230340011, Example 27. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629735&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312748 485657404 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341098 Cl.C[C@H](CCC(=O)N(C)OCCN)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H46N2O3.ClH/c1-18(5-10-25(31)29(4)32-16-15-28)22-8-9-23-21-7-6-19-17-20(30)11-13-26(19,2)24(21)12-14-27(22,23)3;/h6,18,20-24,30H,5,7-17,28H2,1-4H3;1H/t18-,20+,21+,22-,23+,24+,26+,27-;/m1./s1 BPVBDPXSABGKRY-KSGNISEOSA-N 629736 US20230340011, Example 28. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629736&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169257266 485657405 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341100 C[C@H](CCC(=O)N(C)OCCC(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H44F3NO3/c1-18(5-10-25(34)32(4)35-16-15-28(29,30)31)22-8-9-23-21-7-6-19-17-20(33)11-13-26(19,2)24(21)12-14-27(22,23)3/h6,18,20-24,33H,5,7-17H2,1-4H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 YRFZPRYSLGANDZ-ZHHJOTBYSA-N 629737 US20230340011, Example 29. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629737&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312782 485657406 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341101 C[C@H](CCC(=O)N(C)OCCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO4/c1-19(6-11-26(32)29(4)33-17-5-16-30)23-9-10-24-22-8-7-20-18-21(31)12-14-27(20,2)25(22)13-15-28(23,24)3/h7,19,21-25,30-31H,5-6,8-18H2,1-4H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 YMCMAYRPLHFBFV-JDTILAPWSA-N 629738 US20230340011, Example 30. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629738&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312869 485657407 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341102 COCCCON(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H49NO4/c1-20(7-12-27(32)30(4)34-18-6-17-33-5)24-10-11-25-23-9-8-21-19-22(31)13-15-28(21,2)26(23)14-16-29(24,25)3/h8,20,22-26,31H,6-7,9-19H2,1-5H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 DQBSWLNYRKQGCW-OHPSOFBHSA-N 629739 US20230340011, Example 31. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629739&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312433 485657408 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341104 C[C@H](CCC(=O)N(C)OCCCC(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H46F3NO3/c1-19(6-11-26(35)33(4)36-17-5-14-29(30,31)32)23-9-10-24-22-8-7-20-18-21(34)12-15-27(20,2)25(22)13-16-28(23,24)3/h7,19,21-25,34H,5-6,8-18H2,1-4H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 LIQURSGYTJECLW-JDTILAPWSA-N 629740 US20230340011, Example 32. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629740&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312350 485657409 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341105 C[C@H](CCC(=O)N1CCCO1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H43NO3/c1-18(5-10-25(30)28-15-4-16-31-28)22-8-9-23-21-7-6-19-17-20(29)11-13-26(19,2)24(21)12-14-27(22,23)3/h6,18,20-24,29H,4-5,7-17H2,1-3H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 XUNLMPTXTKERAC-ZHHJOTBYSA-N 629741 US20230340011, Example 33. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629741&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311981 485657410 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341827 C[C@H](COc1cccc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO2/c1-18(17-31-26-7-5-6-19(2)29-26)23-10-11-24-22-9-8-20-16-21(30)12-14-27(20,3)25(22)13-15-28(23,24)4/h5-8,18,21-25,30H,9-17H2,1-4H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 PLIHXRWYKLMIOG-JBZGATTQSA-N 629965 US20230340011, Example 264.::US20230340011, Example 440. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629965&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312415 485657630 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341831 C[C@H](COc1ncccc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO2/c1-18-6-5-15-29-26(18)31-17-19(2)23-9-10-24-22-8-7-20-16-21(30)11-13-27(20,3)25(22)12-14-28(23,24)4/h5-7,15,19,21-25,30H,8-14,16-17H2,1-4H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 LTSIUPLOJMIKEM-JDTILAPWSA-N 629962 US20230340011, Example 261.::US20230340011, Example 443. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629962&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312064 485657627 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341833 C[C@H](COc1cccc(CO)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO3/c1-18(17-32-26-6-4-5-20(16-30)29-26)23-9-10-24-22-8-7-19-15-21(31)11-13-27(19,2)25(22)12-14-28(23,24)3/h4-7,18,21-25,30-31H,8-17H2,1-3H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 ICXOUWGBSVIOAJ-JBZGATTQSA-N 629961 US20230340011, Example 260.::US20230340011, Example 444. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629961&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312346 485657626 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341836 C[C@H](COc1cc(CO)ccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO3/c1-18(17-32-26-14-19(16-30)10-13-29-26)23-6-7-24-22-5-4-20-15-21(31)8-11-27(20,2)25(22)9-12-28(23,24)3/h4,10,13-14,18,21-25,30-31H,5-9,11-12,15-17H2,1-3H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 CCFRUMFQTIPSGM-JBZGATTQSA-N 629959 US20230340011, Example 258.::US20230340011, Example 446. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629959&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312597 485657624 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341838 C[C@H](COc1ncccc1C(O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H39NO4/c1-17(16-33-25-21(26(31)32)5-4-14-29-25)22-8-9-23-20-7-6-18-15-19(30)10-12-27(18,2)24(20)11-13-28(22,23)3/h4-6,14,17,19-20,22-24,30H,7-13,15-16H2,1-3H3,(H,31,32)/t17-,19+,20+,22-,23+,24+,27+,28-/m1/s1 SHPZUOIJJWLTEJ-HKTHJWBRSA-N 630147 US20230340011, Example 447. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630147&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311947 485657766 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341841 CNC(=O)c1ccc(OC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)nc1 InChI=1S/C29H42N2O3/c1-18(17-34-26-10-5-19(16-31-26)27(33)30-4)23-8-9-24-22-7-6-20-15-21(32)11-13-28(20,2)25(22)12-14-29(23,24)3/h5-6,10,16,18,21-25,32H,7-9,11-15,17H2,1-4H3,(H,30,33)/t18-,21+,22+,23-,24+,25+,28+,29-/m1/s1 TYDCOVHTGVPQGO-GZDCHJOESA-N 629956 US20230340011, Example 255.::US20230340011, Example 449. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629956&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312528 485657621 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341844 CNC(=O)c1cccnc1OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H42N2O3/c1-18(17-34-27-22(26(33)30-4)6-5-15-31-27)23-9-10-24-21-8-7-19-16-20(32)11-13-28(19,2)25(21)12-14-29(23,24)3/h5-7,15,18,20-21,23-25,32H,8-14,16-17H2,1-4H3,(H,30,33)/t18-,20+,21+,23-,24+,25+,28+,29-/m1/s1 DUJIOAYQHYTAHP-QLEUTBLDSA-N 629954 US20230340011, Example 253.::US20230340011, Example 451. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629954&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312031 485657619 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341846 C[C@H](CCC(=O)N1CCC(CC1)OC(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H47F2NO3/c1-19(4-9-27(35)33-16-12-22(13-17-33)36-28(31)32)24-7-8-25-23-6-5-20-18-21(34)10-14-29(20,2)26(23)11-15-30(24,25)3/h5,19,21-26,28,34H,4,6-18H2,1-3H3/t19-,21+,23+,24-,25+,26+,29+,30-/m1/s1 LJMWOVNHXXOCQR-KIGGCCEQSA-N 629953 US20230340011, Example 252.::US20230340011, Example 452. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629953&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312686 485657618 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341848 C[C@H](CCC(=O)N1CCC(CC1)OC(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H46F3NO3/c1-19(4-9-27(36)34-16-12-22(13-17-34)37-30(31,32)33)24-7-8-25-23-6-5-20-18-21(35)10-14-28(20,2)26(23)11-15-29(24,25)3/h5,19,21-26,35H,4,6-18H2,1-3H3/t19-,21+,23+,24-,25+,26+,28+,29-/m1/s1 DWYMQLFUQAQOBG-KHMNCEKASA-N 629952 US20230340011, Example 251.::US20230340011, Example 453. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629952&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312224 485657617 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341850 C[C@H](CCc1ncccc1CO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H43NO2/c1-19(6-11-27-20(18-31)5-4-16-30-27)24-9-10-25-23-8-7-21-17-22(32)12-14-28(21,2)26(23)13-15-29(24,25)3/h4-5,7,16,19,22-26,31-32H,6,8-15,17-18H2,1-3H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 ZZDJDMMSFPXVHM-HSIBUNQISA-N 629951 US20230340011, Example 250.::US20230340011, Example 454. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629951&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312446 485657616 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341852 C[C@H](CCc1ncccc1C(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H45NO2/c1-19(7-12-28-23(20(2)32)6-5-17-31-28)25-10-11-26-24-9-8-21-18-22(33)13-15-29(21,3)27(24)14-16-30(25,26)4/h5-6,8,17,19-20,22,24-27,32-33H,7,9-16,18H2,1-4H3/t19-,20?,22+,24+,25-,26+,27+,29+,30-/m1/s1 DSAIHBOVBTWQFB-LPCIFWECSA-N 629950 US20230340011, Example 249.::US20230340011, Example 455. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629950&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312916 485657615 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341854 C[C@H](CCc1ncccc1C(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H47NO2/c1-20(8-13-28-27(29(2,3)34)7-6-18-32-28)24-11-12-25-23-10-9-21-19-22(33)14-16-30(21,4)26(23)15-17-31(24,25)5/h6-7,9,18,20,22-26,33-34H,8,10-17,19H2,1-5H3/t20-,22+,23+,24-,25+,26+,30+,31-/m1/s1 OGIATJNVLIWGCR-HCJGDWAISA-N 629949 US20230340011, Example 248.::US20230340011, Example 456. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629949&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312009 485657614 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341856 CCOc1cccnc1CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H45NO2/c1-5-33-28-7-6-18-31-27(28)13-8-20(2)24-11-12-25-23-10-9-21-19-22(32)14-16-29(21,3)26(23)15-17-30(24,25)4/h6-7,9,18,20,22-26,32H,5,8,10-17,19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 KPNCKWIPTNGMEO-RFWRZFGQSA-N 629948 US20230340011, Example 247.::US20230340011, Example 457.::US20230340011, Example 458. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629948&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312018 485657613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341858 CCOc1cccnc1CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H45NO2/c1-5-33-28-7-6-18-31-27(28)13-8-20(2)24-11-12-25-23-10-9-21-19-22(32)14-16-29(21,3)26(23)15-17-30(24,25)4/h6-7,9,18,20,22-26,32H,5,8,10-17,19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 KPNCKWIPTNGMEO-RFWRZFGQSA-N 629948 US20230340011, Example 247.::US20230340011, Example 457.::US20230340011, Example 458. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629948&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312018 485657613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341861 COCCNC(=O)OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H43NO4/c1-17(16-31-24(29)27-13-14-30-4)21-7-8-22-20-6-5-18-15-19(28)9-11-25(18,2)23(20)10-12-26(21,22)3/h5,17,19-23,28H,6-16H2,1-4H3,(H,27,29)/t17-,19+,20+,21-,22+,23+,25+,26-/m1/s1 XUKBMDFYRZGZTM-LXVLQKCJSA-N 629945 US20230340011, Example 244.::US20230340011, Example 460. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629945&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311967 485657610 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341867 COC(=O)N1CCN(CC1)C(=O)OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H46N2O5/c1-19(18-36-27(34)31-15-13-30(14-16-31)26(33)35-4)23-7-8-24-22-6-5-20-17-21(32)9-11-28(20,2)25(22)10-12-29(23,24)3/h5,19,21-25,32H,6-18H2,1-4H3/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 GTTCGLAKJVFWSD-YIZNBMETSA-N 629939 US20230340011, Example 238.::US20230340011, Example 465. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312680 485657604 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341107 C[C@H](CCC(=O)N1CCCCO1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3/c1-19(6-11-26(31)29-16-4-5-17-32-29)23-9-10-24-22-8-7-20-18-21(30)12-14-27(20,2)25(22)13-15-28(23,24)3/h7,19,21-25,30H,4-6,8-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 YWXBAGSVJUIFDU-JDTILAPWSA-N 629742 US20230340011, Example 34. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629742&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312809 485657411 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341109 C[C@H](OC(=O)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C25H39NO4/c1-15(30-23(29)22(28)26(4)5)19-8-9-20-18-7-6-16-14-17(27)10-12-24(16,2)21(18)11-13-25(19,20)3/h6,15,17-21,27H,7-14H2,1-5H3/t15-,17-,18-,19+,20-,21-,24-,25+/m0/s1 GUZVQJUTIWTUCT-OMONWTICSA-N 629743 US20230340011, Example 35. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629743&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312669 485657412 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341111 CON(C1CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3/c1-18(5-12-26(31)29(32-4)20-7-8-20)23-10-11-24-22-9-6-19-17-21(30)13-15-27(19,2)25(22)14-16-28(23,24)3/h6,18,20-25,30H,5,7-17H2,1-4H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 SRIRHESFIMVQGY-JBZGATTQSA-N 629744 US20230340011, Example 36. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629744&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312497 485657413 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341113 C[C@H](CCC(=O)N(C)OC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3/c1-18(5-12-26(31)29(4)32-21-7-8-21)23-10-11-24-22-9-6-19-17-20(30)13-15-27(19,2)25(22)14-16-28(23,24)3/h6,18,20-25,30H,5,7-17H2,1-4H3/t18-,20+,22+,23-,24+,25+,27+,28-/m1/s1 VQWUGWFIPCABAB-YIIXMKGVSA-N 629745 US20230340011, Example 37. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629745&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312043 485657414 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341114 CON(C1CCC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-19(8-13-27(32)30(33-4)21-6-5-7-21)24-11-12-25-23-10-9-20-18-22(31)14-16-28(20,2)26(23)15-17-29(24,25)3/h9,19,21-26,31H,5-8,10-18H2,1-4H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 GLRHQSOFJKSPJZ-HSIBUNQISA-N 629746 US20230340011, Example 38. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629746&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312091 485657415 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341115 C[C@H](CCC(=O)N(C)OC1CCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-19(8-13-27(32)30(4)33-22-6-5-7-22)24-11-12-25-23-10-9-20-18-21(31)14-16-28(20,2)26(23)15-17-29(24,25)3/h9,19,21-26,31H,5-8,10-18H2,1-4H3/t19-,21+,23+,24-,25+,26+,28+,29-/m1/s1 UNXYNQHJVQQZDR-KHMNCEKASA-N 629747 US20230340011, Example 39. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629747&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312276 485657416 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341116 CON(CC1CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-19(5-12-27(32)30(33-4)18-20-6-7-20)24-10-11-25-23-9-8-21-17-22(31)13-15-28(21,2)26(23)14-16-29(24,25)3/h8,19-20,22-26,31H,5-7,9-18H2,1-4H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 HBDLXFHCMFMYCB-HSIBUNQISA-N 629748 US20230340011, Example 40. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629748&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312811 485657417 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341117 C[C@H](CCC(=O)N(C)OCC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-19(5-12-27(32)30(4)33-18-20-6-7-20)24-10-11-25-23-9-8-21-17-22(31)13-15-28(21,2)26(23)14-16-29(24,25)3/h8,19-20,22-26,31H,5-7,9-18H2,1-4H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 FHLQWWJNPPOIPA-HSIBUNQISA-N 629749 US20230340011, Example 41. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629749&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312358 485657418 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341119 C[C@H](CCC(=O)N1CC[C@@H](CO)O1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO4/c1-18(4-9-26(32)29-15-12-21(17-30)33-29)23-7-8-24-22-6-5-19-16-20(31)10-13-27(19,2)25(22)11-14-28(23,24)3/h5,18,20-25,30-31H,4,6-17H2,1-3H3/t18-,20+,21+,22+,23-,24+,25+,27+,28-/m1/s1 IJHUEXQBUWTYBE-QNKMPZKGSA-N 629750 US20230340011, Example 42. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629750&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312602 485657419 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341121 C[C@H](CCC(=O)N1CC[C@H](CO)O1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO4/c1-18(4-9-26(32)29-15-12-21(17-30)33-29)23-7-8-24-22-6-5-19-16-20(31)10-13-27(19,2)25(22)11-14-28(23,24)3/h5,18,20-25,30-31H,4,6-17H2,1-3H3/t18-,20+,21-,22+,23-,24+,25+,27+,28-/m1/s1 IJHUEXQBUWTYBE-UADQAFFDSA-N 629751 US20230340011, Example 43. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312841 485657420 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341123 C[C@H](CCC(=O)N1OC[C@@H]2CN(CC=C)C[C@H]12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O3/c1-5-16-33-18-22-20-37-34(29(22)19-33)30(36)11-6-21(2)26-9-10-27-25-8-7-23-17-24(35)12-14-31(23,3)28(25)13-15-32(26,27)4/h5,7,21-22,24-29,35H,1,6,8-20H2,2-4H3/t21-,22+,24+,25+,26-,27+,28+,29+,31+,32-/m1/s1 WYBROSOKNOBFEO-OYFVJFOASA-N 629752 (R)-1-((3aR,6aR)-5-allylhexahydro-1H-pyrrolo[3,4-c]isoxazol-1-yl)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentan-1-one::US20230340011, Example 44.::US20230340011, Example 45. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312442 485657421 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341125 C[C@H](CCC(=O)N1OC[C@@H]2CN(CC=C)C[C@H]12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O3/c1-5-16-33-18-22-20-37-34(29(22)19-33)30(36)11-6-21(2)26-9-10-27-25-8-7-23-17-24(35)12-14-31(23,3)28(25)13-15-32(26,27)4/h5,7,21-22,24-29,35H,1,6,8-20H2,2-4H3/t21-,22+,24+,25+,26-,27+,28+,29+,31+,32-/m1/s1 WYBROSOKNOBFEO-OYFVJFOASA-N 629752 (R)-1-((3aR,6aR)-5-allylhexahydro-1H-pyrrolo[3,4-c]isoxazol-1-yl)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentan-1-one::US20230340011, Example 44.::US20230340011, Example 45. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629752&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312442 485657421 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341127 C[C@H](CCC(=O)N1OC[C@H]2CN(CC=C)C[C@@H]12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O3/c1-5-16-33-18-22-20-37-34(29(22)19-33)30(36)11-6-21(2)26-9-10-27-25-8-7-23-17-24(35)12-14-31(23,3)28(25)13-15-32(26,27)4/h5,7,21-22,24-29,35H,1,6,8-20H2,2-4H3/t21-,22-,24+,25+,26-,27+,28+,29-,31+,32-/m1/s1 WYBROSOKNOBFEO-QJXLSNHTSA-N 629754 US20230340011, Example 46. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629754&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312371 485657422 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341129 CC[C@H]1NC[C@@H]2CON([C@H]12)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-5-27-29-20(17-32-27)18-36-33(29)28(35)11-6-19(2)24-9-10-25-23-8-7-21-16-22(34)12-14-30(21,3)26(23)13-15-31(24,25)4/h7,19-20,22-27,29,32,34H,5-6,8-18H2,1-4H3/t19-,20-,22+,23+,24-,25+,26+,27-,29+,30+,31-/m1/s1 BCIFXAXIRJLNAW-VFADNPFTSA-N 629755 US20230340011, Example 47. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629755&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312657 485657423 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341131 CC[C@@H]1NC[C@@H]2CON([C@H]12)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-5-27-29-20(17-32-27)18-36-33(29)28(35)11-6-19(2)24-9-10-25-23-8-7-21-16-22(34)12-14-30(21,3)26(23)13-15-31(24,25)4/h7,19-20,22-27,29,32,34H,5-6,8-18H2,1-4H3/t19-,20-,22+,23+,24-,25+,26+,27+,29+,30+,31-/m1/s1 BCIFXAXIRJLNAW-GTFXUSNLSA-N 629756 US20230340011, Example 48. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629756&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312906 485657424 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341133 C[C@H](CCC(=O)N1OC(C)(C)[C@H]2COC[C@@H]12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49NO4/c1-19(6-11-28(34)32-27-18-35-17-26(27)29(2,3)36-32)23-9-10-24-22-8-7-20-16-21(33)12-14-30(20,4)25(22)13-15-31(23,24)5/h7,19,21-27,33H,6,8-18H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-,30+,31-/m1/s1 QKUHXOAMBHFAGC-ARAYUJIUSA-N 629757 US20230340011, Example 49. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629757&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312798 485657425 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341134 C[C@H](CCC(=O)N1O[C@@H]([C@H]2CCC[C@@H]12)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H51NO3/c1-23(12-17-33(39)37-32-11-7-10-28(32)34(40-37)24-8-5-4-6-9-24)29-15-16-30-27-14-13-25-22-26(38)18-20-35(25,2)31(27)19-21-36(29,30)3/h4-6,8-9,13,23,26-32,34,38H,7,10-12,14-22H2,1-3H3/t23-,26+,27+,28+,29-,30+,31+,32-,34-,35+,36-/m1/s1 SRRJGRPBKMGUQE-WMKXVGLGSA-N 629758 US20230340011, Example 50. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629758&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311939 485657426 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341136 C[C@H](CCC(=O)N1O[C@H]([C@H]2CCC[C@@H]12)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H51NO3/c1-23(12-17-33(39)37-32-11-7-10-28(32)34(40-37)24-8-5-4-6-9-24)29-15-16-30-27-14-13-25-22-26(38)18-20-35(25,2)31(27)19-21-36(29,30)3/h4-6,8-9,13,23,26-32,34,38H,7,10-12,14-22H2,1-3H3/t23-,26+,27+,28+,29-,30+,31+,32-,34+,35+,36-/m1/s1 SRRJGRPBKMGUQE-LCUQJJPGSA-N 629759 US20230340011, Example 51. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629759&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312535 485657427 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341137 C[C@H](CCC(=O)N1O[C@H]([C@@H]2CCC[C@H]12)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H51NO3/c1-23(12-17-33(39)37-32-11-7-10-28(32)34(40-37)24-8-5-4-6-9-24)29-15-16-30-27-14-13-25-22-26(38)18-20-35(25,2)31(27)19-21-36(29,30)3/h4-6,8-9,13,23,26-32,34,38H,7,10-12,14-22H2,1-3H3/t23-,26+,27+,28-,29-,30+,31+,32+,34+,35+,36-/m1/s1 SRRJGRPBKMGUQE-APPQDVIHSA-N 629760 US20230340011, Example 52 Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629760&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312917 485657428 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341139 C[C@H](CCC(=O)N1O[C@@H]([C@@H]2CCC[C@H]12)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H51NO3/c1-23(12-17-33(39)37-32-11-7-10-28(32)34(40-37)24-8-5-4-6-9-24)29-15-16-30-27-14-13-25-22-26(38)18-20-35(25,2)31(27)19-21-36(29,30)3/h4-6,8-9,13,23,26-32,34,38H,7,10-12,14-22H2,1-3H3/t23-,26+,27+,28-,29-,30+,31+,32+,34-,35+,36-/m1/s1 SRRJGRPBKMGUQE-QCVDQBPCSA-N 629761 US20230340011, Example 53. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629761&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312933 485657429 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341140 C[C@H](CCC(=O)N1O[C@H]2C[C@@H]1[C@H](O)[C@@H]2O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H45NO5/c1-16(4-9-25(32)30-23-15-24(35-30)27(34)26(23)33)20-7-8-21-19-6-5-17-14-18(31)10-12-28(17,2)22(19)11-13-29(20,21)3/h5,16,18-24,26-27,31,33-34H,4,6-15H2,1-3H3/t16-,18+,19+,20-,21+,22+,23-,24+,26+,27-,28+,29-/m1/s1 DILRKBRPAFXCLK-XFHNKFRVSA-N 629762 US20230340011, Example 54. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629762&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312157 485657430 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341141 C[C@H](CCC(=O)N1O[C@@H]2C[C@H]1[C@@H](O)[C@H]2O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H45NO5/c1-16(4-9-25(32)30-23-15-24(35-30)27(34)26(23)33)20-7-8-21-19-6-5-17-14-18(31)10-12-28(17,2)22(19)11-13-29(20,21)3/h5,16,18-24,26-27,31,33-34H,4,6-15H2,1-3H3/t16-,18+,19+,20-,21+,22+,23+,24-,26-,27+,28+,29-/m1/s1 DILRKBRPAFXCLK-HLEDILBRSA-N 629763 US20230340011, Example 55. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629763&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312591 485657431 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341142 C[C@H](CCC(=O)N1CCCCCO1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-20(7-12-27(32)30-17-5-4-6-18-33-30)24-10-11-25-23-9-8-21-19-22(31)13-15-28(21,2)26(23)14-16-29(24,25)3/h8,20,22-26,31H,4-7,9-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 DUJVLAGFPNQTCT-OHPSOFBHSA-N 629764 US20230340011, Example 56. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629764&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312184 485657432 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341143 C[C@H](CCC(=O)N1OCC[C@@H]1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3/c1-18(5-10-26(31)29-19(2)13-16-32-29)23-8-9-24-22-7-6-20-17-21(30)11-14-27(20,3)25(22)12-15-28(23,24)4/h6,18-19,21-25,30H,5,7-17H2,1-4H3/t18-,19+,21+,22+,23-,24+,25+,27+,28-/m1/s1 VMILGPLGMGVHNG-WEBRBZGQSA-N 629765 US20230340011, Example 57 Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629765&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312179 485657433 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341144 C[C@H](CCC(=O)N1C[C@@H](C)CO1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3/c1-18-16-29(32-17-18)26(31)10-5-19(2)23-8-9-24-22-7-6-20-15-21(30)11-13-27(20,3)25(22)12-14-28(23,24)4/h6,18-19,21-25,30H,5,7-17H2,1-4H3/t18-,19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 HLWAZIHOCRRZKQ-NELWDGDQSA-N 629766 US20230340011, Example 58. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629766&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312595 485657434 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341145 C[C@H](CCC(=O)N1CC[C@@H](C)O1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO3/c1-18(5-10-26(31)29-16-13-19(2)32-29)23-8-9-24-22-7-6-20-17-21(30)11-14-27(20,3)25(22)12-15-28(23,24)4/h6,18-19,21-25,30H,5,7-17H2,1-4H3/t18-,19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 GTHLUOFTPXHSOV-NELWDGDQSA-N 629767 US20230340011, Example 59. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629767&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311910 485657435 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341146 C[C@H](CCC(=O)N1CCC[C@@H](C)O1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-19(7-12-27(32)30-17-5-6-20(2)33-30)24-10-11-25-23-9-8-21-18-22(31)13-15-28(21,3)26(23)14-16-29(24,25)4/h8,19-20,22-26,31H,5-7,9-18H2,1-4H3/t19-,20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 LHSBITNALUCKRX-PKCZXNRQSA-N 629768 US20230340011, Example 60. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629768&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312508 485657436 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341147 C[C@H](CCC(=O)N(C)OC1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(9-14-28(33)31(4)34-23-7-5-6-8-23)25-12-13-26-24-11-10-21-19-22(32)15-17-29(21,2)27(24)16-18-30(25,26)3/h10,20,22-27,32H,5-9,11-19H2,1-4H3/t20-,22+,24+,25-,26+,27+,29+,30-/m1/s1 GNXLCQQBDDVRBE-UZKJJXDZSA-N 629769 US20230340011, Example 61. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629769&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312621 485657437 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341149 CON(CCO)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO4/c1-18(5-10-25(31)28(32-4)15-16-29)22-8-9-23-21-7-6-19-17-20(30)11-13-26(19,2)24(21)12-14-27(22,23)3/h6,18,20-24,29-30H,5,7-17H2,1-4H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 VKBATOIQVZQREE-ZHHJOTBYSA-N 629770 (R)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-N-(2-hydroxyethyl)-N-methoxypentanamide::US20230340011, Example 62. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629770&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312272 485657438 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341151 CON(CC(O)=O)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H43NO5/c1-17(5-10-24(30)28(33-4)16-25(31)32)21-8-9-22-20-7-6-18-15-19(29)11-13-26(18,2)23(20)12-14-27(21,22)3/h6,17,19-23,29H,5,7-16H2,1-4H3,(H,31,32)/t17-,19+,20+,21-,22+,23+,26+,27-/m1/s1 HDQCGBHRYNQICK-QWMOJLDXSA-N 629771 US20230340011, Example 63. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629771&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311964 485657439 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341153 CON(CCN)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H46N2O3/c1-18(5-10-25(31)29(32-4)16-15-28)22-8-9-23-21-7-6-19-17-20(30)11-13-26(19,2)24(21)12-14-27(22,23)3/h6,18,20-24,30H,5,7-17,28H2,1-4H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 DLIGEYTVUWDKGR-ZHHJOTBYSA-N 629772 US20230340011, Example 64. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629772&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311862 485657440 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341155 CON(CCC(F)(F)F)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H44F3NO3/c1-18(5-10-25(34)32(35-4)16-15-28(29,30)31)22-8-9-23-21-7-6-19-17-20(33)11-13-26(19,2)24(21)12-14-27(22,23)3/h6,18,20-24,33H,5,7-17H2,1-4H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 RKTSUPNCBGWTIK-ZHHJOTBYSA-N 629773 US20230340011, Example 65. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629773&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312515 485657441 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341157 CON([C@H](C)CO)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO4/c1-18(6-11-26(32)29(33-5)19(2)17-30)23-9-10-24-22-8-7-20-16-21(31)12-14-27(20,3)25(22)13-15-28(23,24)4/h7,18-19,21-25,30-31H,6,8-17H2,1-5H3/t18-,19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 RLCLYFXZYVWNTP-NELWDGDQSA-N 629774 (4R)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-N-(1-hydroxypropan-2-yl)-N-methoxypentanamide::US20230340011, Example 66.::US20230340011, Example 71. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629774&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312672 485657442 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341158 CON(CC(C)C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H49NO3/c1-19(2)18-30(33-6)27(32)12-7-20(3)24-10-11-25-23-9-8-21-17-22(31)13-15-28(21,4)26(23)14-16-29(24,25)5/h8,19-20,22-26,31H,7,9-18H2,1-6H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 SAVLIBDCAHOHRH-OHPSOFBHSA-N 629775 US20230340011, Example 67. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629775&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312881 485657443 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341870 COC(=O)N1CCN(CC1)C(=O)NC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47N3O4/c1-19(18-30-26(34)31-13-15-32(16-14-31)27(35)36-4)23-7-8-24-22-6-5-20-17-21(33)9-11-28(20,2)25(22)10-12-29(23,24)3/h5,19,21-25,33H,6-18H2,1-4H3,(H,30,34)/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 PCWWWYUYYWJLQQ-YIZNBMETSA-N 629937 US20230340011, Example 236.::US20230340011, Example 467. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629937&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312509 485657602 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341873 COC(C)C1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55NO3/c1-22(7-10-30(36)34-19-14-24(15-20-34)23(2)37-6)27-12-17-33(5)29-9-8-25-21-26(35)11-16-31(25,3)28(29)13-18-32(27,33)4/h8,22-24,26-29,35H,7,9-21H2,1-6H3/t22-,23?,26+,27-,28+,29-,31+,32-,33+/m1/s1 OYIIOZJQSSHZLQ-HVVFFQFXSA-N 630169 US20230340011, Example 469. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630169&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312094 485657768 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341877 C[C@H](CCC(=O)N1CCC(CNS(C)(=O)=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O4S/c1-21(5-10-29(35)33-17-13-22(14-18-33)20-32-38(4,36)37)26-8-9-27-25-7-6-23-19-24(34)11-15-30(23,2)28(25)12-16-31(26,27)3/h6,21-22,24-28,32,34H,5,7-20H2,1-4H3/t21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 DACBBFAVSCNZII-ANSWHRQLSA-N 629934 US20230340011, Example 232.::US20230340011, Example 472. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629934&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312545 485657599 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341879 C[C@H](CCC(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49F3N2O4S/c1-20(4-9-28(38)36-16-12-21(13-17-36)19-35-41(39,40)31(32,33)34)25-7-8-26-24-6-5-22-18-23(37)10-14-29(22,2)27(24)11-15-30(25,26)3/h5,20-21,23-27,35,37H,4,6-19H2,1-3H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 WPEDDRBYKBFFOQ-CMZGQUJUSA-N 629933 US20230340011, Example 231.::US20230340011, Example 473. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629933&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312671 485657598 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341881 C[C@H](CCC(=O)N1CCC(CN(C)S(C)(=O)=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H54N2O4S/c1-22(6-11-30(36)34-18-14-23(15-19-34)21-33(4)39(5,37)38)27-9-10-28-26-8-7-24-20-25(35)12-16-31(24,2)29(26)13-17-32(27,28)3/h7,22-23,25-29,35H,6,8-21H2,1-5H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 MVAUARKOZFQLRC-NWKCFVCZSA-N 629932 US20230340011, Example 230.::US20230340011, Example 474. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629932&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312280 485657597 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341883 C[C@H](CCC(=O)N1CCC(CC1)C(C)NS(C)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H54N2O4S/c1-21(6-11-30(36)34-18-14-23(15-19-34)22(2)33-39(5,37)38)27-9-10-28-26-8-7-24-20-25(35)12-16-31(24,3)29(26)13-17-32(27,28)4/h7,21-23,25-29,33,35H,6,8-20H2,1-5H3/t21-,22?,25+,26+,27-,28+,29+,31+,32-/m1/s1 FTMWXGJEOQCRSI-TWKOBVMPSA-N 629931 US20230340011, Example 229.::US20230340011, Example 475. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629931&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312432 485657596 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341889 C[C@H](CCC(=O)N1CCN(CC1)c1ccnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N4O2/c1-22(5-10-30(38)36-19-17-35(18-20-36)29-13-16-33-34(29)4)26-8-9-27-25-7-6-23-21-24(37)11-14-31(23,2)28(25)12-15-32(26,27)3/h6,13,16,22,24-28,37H,5,7-12,14-15,17-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 BQGAVEMLTLEGMS-XJGPRUKRSA-N 629928 US20230340011, Example 226.::US20230340011, Example 480. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629928&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312321 485657593 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341891 C[C@H](CCC(=O)N1CCN(CC1)c1cncn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N4O2/c1-22(5-10-30(38)36-17-15-35(16-18-36)29-20-33-21-34(29)4)26-8-9-27-25-7-6-23-19-24(37)11-13-31(23,2)28(25)12-14-32(26,27)3/h6,20-22,24-28,37H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 SPEDKLXJXIBESP-XJGPRUKRSA-N 630181 US20230340011, Example 481. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630181&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312793 485657772 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341893 C[C@H](CCC(=O)N1CCN(CC1)c1nnc(C)o1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N4O3/c1-20(5-10-28(37)34-15-17-35(18-16-34)29-33-32-21(2)38-29)25-8-9-26-24-7-6-22-19-23(36)11-13-30(22,3)27(24)12-14-31(25,26)4/h6,20,23-27,36H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,30+,31-/m1/s1 NMHOSRIPKLKBBI-NBDGSGAJSA-N 630182 (R)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1-(4-(5-methyl-1,3,4-oxadiazol-2-yl)piperazin-1-yl)pentan-1-one::US20230340011, Example 482. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630182&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312015 485657773 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341895 C[C@H](CCC(=O)N1CCN(CC1)c1nnc(C)s1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N4O2S/c1-20(5-10-28(37)34-15-17-35(18-16-34)29-33-32-21(2)38-29)25-8-9-26-24-7-6-22-19-23(36)11-13-30(22,3)27(24)12-14-31(25,26)4/h6,20,23-27,36H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,30+,31-/m1/s1 LLJXRHHEXGCVNW-NBDGSGAJSA-N 629927 US20230340011, Example 225.::US20230340011, Example 483. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629927&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312664 485657592 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341897 C[C@H](CCC(=O)N1CCN(Cc2cncnc2)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-23(4-9-31(39)37-16-14-36(15-17-37)21-24-19-34-22-35-20-24)28-7-8-29-27-6-5-25-18-26(38)10-12-32(25,2)30(27)11-13-33(28,29)3/h5,19-20,22-23,26-30,38H,4,6-18,21H2,1-3H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 FTCDWVMHXIFDOO-ZWWVIQJBSA-N 629926 US20230340011, Example 224.::US20230340011, Example 484. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629926&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312218 485657591 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341899 C[C@H](CCC(=O)N1CCN(Cc2cnn(C)c2)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N4O2/c1-23(5-10-31(39)37-17-15-36(16-18-37)22-24-20-34-35(4)21-24)28-8-9-29-27-7-6-25-19-26(38)11-13-32(25,2)30(27)12-14-33(28,29)3/h6,20-21,23,26-30,38H,5,7-19,22H2,1-4H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 CDOZILNPFAZLRV-ZWWVIQJBSA-N 629925 US20230340011, Example 223.::US20230340011, Example 485. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629925&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312892 485657590 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341901 C[C@H](CCC(=O)N1CCN(CC1)c1cncnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(4-9-30(38)36-16-14-35(15-17-36)24-19-33-21-34-20-24)27-7-8-28-26-6-5-23-18-25(37)10-12-31(23,2)29(26)11-13-32(27,28)3/h5,19-22,25-29,37H,4,6-18H2,1-3H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 KSXZNNYPOJLTTN-NWKCFVCZSA-N 629924 US20230340011, Example 222.::US20230340011, Example 486. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629924&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312041 485657589 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341903 C[C@H](CCC(=O)N1CCN(CC1)c1ccnnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(4-9-30(38)36-18-16-35(17-19-36)24-12-15-33-34-21-24)27-7-8-28-26-6-5-23-20-25(37)10-13-31(23,2)29(26)11-14-32(27,28)3/h5,12,15,21-22,25-29,37H,4,6-11,13-14,16-20H2,1-3H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 IJMSYCRKGWJQDL-NWKCFVCZSA-N 630187 US20230340011, Example 487. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630187&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312275 485657774 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341905 C[C@H](CCC(=O)N1CCC(CC1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(4-9-31(38)36-18-13-25(14-19-36)39-30-12-17-34-21-35-30)27-7-8-28-26-6-5-23-20-24(37)10-15-32(23,2)29(26)11-16-33(27,28)3/h5,12,17,21-22,24-29,37H,4,6-11,13-16,18-20H2,1-3H3/t22-,24+,26+,27-,28+,29+,32+,33-/m1/s1 LWYPURHDORNXGY-LRVBENBSSA-N 629923 US20230340011, Example 221.::US20230340011, Example 488. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629923&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312148 485657588 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341907 C[C@H](CCC(=O)N1CCC(CC1)Oc1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(4-9-31(38)36-18-12-25(13-19-36)39-30-21-34-16-17-35-30)27-7-8-28-26-6-5-23-20-24(37)10-14-32(23,2)29(26)11-15-33(27,28)3/h5,16-17,21-22,24-29,37H,4,6-15,18-20H2,1-3H3/t22-,24+,26+,27-,28+,29+,32+,33-/m1/s1 KXSGPQDVIBVOHS-LRVBENBSSA-N 629922 US20230340011, Example 220.::US20230340011, Example 489. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629922&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312261 485657587 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341909 C[C@H](CCC(=O)N1CCC(CC1)Oc1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O3/c1-23(6-11-32(38)36-19-14-26(15-20-36)39-27-5-4-18-35-22-27)29-9-10-30-28-8-7-24-21-25(37)12-16-33(24,2)31(28)13-17-34(29,30)3/h4-5,7,18,22-23,25-26,28-31,37H,6,8-17,19-21H2,1-3H3/t23-,25+,28+,29-,30+,31+,33+,34-/m1/s1 JHSOYPWRPHDAAP-HJIUKPPKSA-N 629921 US20230340011, Example 219.::US20230340011, Example 490. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629921&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312816 485657586 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341911 C[C@H](CCC(=O)N1CCC[C@@H](C1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(6-11-31(38)36-18-4-5-25(20-36)39-30-14-17-34-21-35-30)27-9-10-28-26-8-7-23-19-24(37)12-15-32(23,2)29(26)13-16-33(27,28)3/h7,14,17,21-22,24-29,37H,4-6,8-13,15-16,18-20H2,1-3H3/t22-,24+,25+,26+,27-,28+,29+,32+,33-/m1/s1 IKXWNSKSLJRNQO-XFRFFNMESA-N 629920 US20230340011, Example 218.::US20230340011, Example 491. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629920&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312849 485657585 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341913 C[C@H](CCC(=O)N1CCC[C@H](C1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(6-11-31(38)36-18-4-5-25(20-36)39-30-14-17-34-21-35-30)27-9-10-28-26-8-7-23-19-24(37)12-15-32(23,2)29(26)13-16-33(27,28)3/h7,14,17,21-22,24-29,37H,4-6,8-13,15-16,18-20H2,1-3H3/t22-,24+,25-,26+,27-,28+,29+,32+,33-/m1/s1 IKXWNSKSLJRNQO-GBHVZMROSA-N 630192 US20230340011, Example 492. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630192&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312524 485657775 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341915 C[C@H](CCC(=O)N1CC[C@@H](C1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H47N3O3/c1-21(4-9-30(37)35-17-13-24(19-35)38-29-12-16-33-20-34-29)26-7-8-27-25-6-5-22-18-23(36)10-14-31(22,2)28(25)11-15-32(26,27)3/h5,12,16,20-21,23-28,36H,4,6-11,13-15,17-19H2,1-3H3/t21-,23+,24+,25+,26-,27+,28+,31+,32-/m1/s1 BCMWWLFUPGUEKZ-FTYDJCRESA-N 629918 US20230340011, Example 216.::US20230340011, Example 493. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629918&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312684 485657583 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341918 C[C@H](CCC(=O)N1CCN(CC1)c1nc(C)no1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N4O3/c1-20(5-10-28(37)34-15-17-35(18-16-34)29-32-21(2)33-38-29)25-8-9-26-24-7-6-22-19-23(36)11-13-30(22,3)27(24)12-14-31(25,26)4/h6,20,23-27,36H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,30+,31-/m1/s1 PHPGYTJIRRZLCC-NBDGSGAJSA-N 630195 US20230340011, Example 495. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630195&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312281 485657776 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341160 CON(C[C@H](C)O)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO4/c1-18(6-11-26(32)29(33-5)17-19(2)30)23-9-10-24-22-8-7-20-16-21(31)12-14-27(20,3)25(22)13-15-28(23,24)4/h7,18-19,21-25,30-31H,6,8-17H2,1-5H3/t18-,19+,21+,22+,23-,24+,25+,27+,28-/m1/s1 XOLINRDLRHZJSM-WEBRBZGQSA-N 629776 US20230340011, Example 69. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629776&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312678 485657444 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341162 CON(C[C@@H](C)O)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO4/c1-18(6-11-26(32)29(33-5)17-19(2)30)23-9-10-24-22-8-7-20-16-21(31)12-14-27(20,3)25(22)13-15-28(23,24)4/h7,18-19,21-25,30-31H,6,8-17H2,1-5H3/t18-,19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 XOLINRDLRHZJSM-NELWDGDQSA-N 629777 US20230340011, Example 70. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629777&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312155 485657445 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341164 CON([C@H](C)CO)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO4/c1-18(6-11-26(32)29(33-5)19(2)17-30)23-9-10-24-22-8-7-20-16-21(31)12-14-27(20,3)25(22)13-15-28(23,24)4/h7,18-19,21-25,30-31H,6,8-17H2,1-5H3/t18-,19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 RLCLYFXZYVWNTP-NELWDGDQSA-N 629774 (4R)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-N-(1-hydroxypropan-2-yl)-N-methoxypentanamide::US20230340011, Example 66.::US20230340011, Example 71. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629774&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312672 485657442 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341166 CON([C@@H](C)CO)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H47NO4/c1-18(6-11-26(32)29(33-5)19(2)17-30)23-9-10-24-22-8-7-20-16-21(31)12-14-27(20,3)25(22)13-15-28(23,24)4/h7,18-19,21-25,30-31H,6,8-17H2,1-5H3/t18-,19+,21+,22+,23-,24+,25+,27+,28-/m1/s1 RLCLYFXZYVWNTP-WEBRBZGQSA-N 629779 US20230340011, Example 72. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629779&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312079 485657446 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341168 CON(CC(=O)OC(C)(C)C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51NO5/c1-20(8-13-27(34)32(36-7)19-28(35)37-29(2,3)4)24-11-12-25-23-10-9-21-18-22(33)14-16-30(21,5)26(23)15-17-31(24,25)6/h9,20,22-26,33H,8,10-19H2,1-7H3/t20-,22+,23+,24-,25+,26+,30+,31-/m1/s1 VWWNEKNRFWXTFB-HCJGDWAISA-N 629781 US20230340011, Example 75. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629781&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312846 485657448 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341170 C[C@H](CCC(=O)N1CCC[C@@H](C1)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H51NO2/c1-24(11-16-33(38)36-21-7-10-26(23-36)25-8-5-4-6-9-25)30-14-15-31-29-13-12-27-22-28(37)17-19-34(27,2)32(29)18-20-35(30,31)3/h4-6,8-9,12,24,26,28-32,37H,7,10-11,13-23H2,1-3H3/t24-,26+,28+,29+,30-,31+,32+,34+,35-/m1/s1 KDXIKDSGZQUKRE-VMJKVMBGSA-N 629782 US20230340011, Example 76.::US20230340011, Example 77. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629782&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312644 485657449 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341172 C[C@H](CCC(=O)N1CCC[C@@H](C1)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H51NO2/c1-24(11-16-33(38)36-21-7-10-26(23-36)25-8-5-4-6-9-25)30-14-15-31-29-13-12-27-22-28(37)17-19-34(27,2)32(29)18-20-35(30,31)3/h4-6,8-9,12,24,26,28-32,37H,7,10-11,13-23H2,1-3H3/t24-,26+,28+,29+,30-,31+,32+,34+,35-/m1/s1 KDXIKDSGZQUKRE-VMJKVMBGSA-N 629782 US20230340011, Example 76.::US20230340011, Example 77. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629782&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312644 485657449 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341174 C[C@H](CCC(=O)N1C[C@@H]2C[C@@]2(C1)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H49NO2/c1-23(9-14-32(38)36-21-26-20-35(26,22-36)24-7-5-4-6-8-24)29-12-13-30-28-11-10-25-19-27(37)15-17-33(25,2)31(28)16-18-34(29,30)3/h4-8,10,23,26-31,37H,9,11-22H2,1-3H3/t23-,26+,27+,28+,29-,30+,31+,33+,34-,35-/m1/s1 OUPKNFASFSACFJ-AYYWMNLUSA-N 629784 US20230340011, Example 78. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629784&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312054 485657450 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341176 C[C@H](CCC(=O)N1CCC(F)(F)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H45F2NO2/c1-19(4-9-26(34)32-16-14-29(30,31)15-17-32)23-7-8-24-22-6-5-20-18-21(33)10-12-27(20,2)25(22)11-13-28(23,24)3/h5,19,21-25,33H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 KFMAUCRUOIHXPM-JDTILAPWSA-N 629785 US20230340011, Example 79. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629785&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312410 485657451 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341178 C[C@H](CCC(=O)N1CCC2(COC2)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49NO3/c1-21(4-9-28(34)32-16-14-31(15-17-32)19-35-20-31)25-7-8-26-24-6-5-22-18-23(33)10-12-29(22,2)27(24)11-13-30(25,26)3/h5,21,23-27,33H,4,6-20H2,1-3H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 OEWSPQJHWRZUIN-NXUCFJMCSA-N 629786 US20230340011, Example 80. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629786&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312189 485657452 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341180 C[C@H](CCC(=O)N1CCCOCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-20(5-10-27(32)30-15-4-17-33-18-16-30)24-8-9-25-23-7-6-21-19-22(31)11-13-28(21,2)26(23)12-14-29(24,25)3/h6,20,22-26,31H,4-5,7-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 OOXAFHDIIXWMRJ-OHPSOFBHSA-N 629787 US20230340011, Example 81. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629787&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312318 485657453 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341182 C[C@H](CCC(=O)N1CCC(CC1)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H46F3NO2/c1-19(4-9-27(36)34-16-12-20(13-17-34)30(31,32)33)24-7-8-25-23-6-5-21-18-22(35)10-14-28(21,2)26(23)11-15-29(24,25)3/h5,19-20,22-26,35H,4,6-18H2,1-3H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 LBCIFMWPRNVZKK-HSIBUNQISA-N 629788 US20230340011, Example 82. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629788&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312073 485657454 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341184 C[C@H](CCC(=O)N1CCC(C)(CC1)NC(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-21(6-11-29(37)34-18-16-30(3,17-19-34)33-22(2)35)26-9-10-27-25-8-7-23-20-24(36)12-14-31(23,4)28(25)13-15-32(26,27)5/h7,21,24-28,36H,6,8-20H2,1-5H3,(H,33,35)/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 VNXDKRPUMZDRFI-XKQUNUCNSA-N 629789 US20230340011, Example 83. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629789&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312607 485657455 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341186 C[C@H](CCC(=O)N1CCC(C)(CC1)NS(C)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O4S/c1-21(6-11-28(35)33-18-16-29(2,17-19-33)32-38(5,36)37)25-9-10-26-24-8-7-22-20-23(34)12-14-30(22,3)27(24)13-15-31(25,26)4/h7,21,23-27,32,34H,6,8-20H2,1-5H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 XDXMKKFNVVCTNH-MIXBDBMTSA-N 629790 US20230340011, Example 84. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629790&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312721 485657456 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341188 C[C@H](CCC(=O)N1CCC(C)(CC1)C(N)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(5-10-27(35)33-17-15-29(2,16-18-33)28(32)36)24-8-9-25-23-7-6-21-19-22(34)11-13-30(21,3)26(23)12-14-31(24,25)4/h6,20,22-26,34H,5,7-19H2,1-4H3,(H2,32,36)/t20-,22+,23+,24-,25+,26+,30+,31-/m1/s1 OPXFVZLUUSDCDO-HCJGDWAISA-N 629791 US20230340011, Example 85. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629791&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312860 485657457 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341190 CNC(=O)C1(C)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-21(6-11-28(36)34-18-16-30(2,17-19-34)29(37)33-5)25-9-10-26-24-8-7-22-20-23(35)12-14-31(22,3)27(24)13-15-32(25,26)4/h7,21,23-27,35H,6,8-20H2,1-5H3,(H,33,37)/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 KXMNHOCNYBSHTK-GTORSBDHSA-N 629792 US20230340011, Example 86. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629792&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312862 485657458 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341192 C[C@H](CCC(=O)N1CCC(C)(CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H54N2O3/c1-22(7-12-29(37)35-19-17-31(2,18-20-35)30(38)34(5)6)26-10-11-27-25-9-8-23-21-24(36)13-15-32(23,3)28(25)14-16-33(26,27)4/h8,22,24-28,36H,7,9-21H2,1-6H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 AOEQMSQEMHEIFG-WKFLPMMISA-N 629793 US20230340011, Example 87. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629793&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311950 485657459 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341194 C[C@H](CCC(=O)N1CCC2(CCCO2)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51NO3/c1-22(5-10-29(35)33-18-16-32(17-19-33)13-4-20-36-32)26-8-9-27-25-7-6-23-21-24(34)11-14-30(23,2)28(25)12-15-31(26,27)3/h6,22,24-28,34H,4-5,7-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,30+,31-/m1/s1 XUCJCQCODRSAPC-GTPODGLVSA-N 629794 US20230340011, Example 88. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629794&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311993 485657460 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341196 C[C@H](CCC(=O)N1CCC2(CCOC2)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51NO3/c1-22(4-9-29(35)33-17-14-32(15-18-33)16-19-36-21-32)26-7-8-27-25-6-5-23-20-24(34)10-12-30(23,2)28(25)11-13-31(26,27)3/h5,22,24-28,34H,4,6-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,30+,31-/m1/s1 CAIHWZKENDFSMY-GTPODGLVSA-N 629795 US20230340011, Example 89. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629795&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312945 485657461 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341198 CC#CC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49NO3/c1-5-14-32(36)17-19-33(20-18-32)29(35)11-6-22(2)26-9-10-27-25-8-7-23-21-24(34)12-15-30(23,3)28(25)13-16-31(26,27)4/h7,22,24-28,34,36H,6,8-13,15-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,30+,31-/m1/s1 JAJUZUMNQXYPHV-GTPODGLVSA-N 629796 US20230340011, Example 90. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629796&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312823 485657462 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341200 C[C@H](CCC(=O)N1CCC(O)(CC1)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H51NO3/c1-24(9-14-32(38)36-21-19-35(39,20-22-36)25-7-5-4-6-8-25)29-12-13-30-28-11-10-26-23-27(37)15-17-33(26,2)31(28)16-18-34(29,30)3/h4-8,10,24,27-31,37,39H,9,11-23H2,1-3H3/t24-,27+,28+,29-,30+,31+,33+,34-/m1/s1 XGCWVPZQUHIRBQ-LLHZKFLPSA-N 629797 US20230340011, Example 91. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629797&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312888 485657463 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341202 CCCCC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55NO3/c1-5-6-15-33(37)18-20-34(21-19-33)30(36)12-7-23(2)27-10-11-28-26-9-8-24-22-25(35)13-16-31(24,3)29(26)14-17-32(27,28)4/h8,23,25-29,35,37H,5-7,9-22H2,1-4H3/t23-,25+,26+,27-,28+,29+,31+,32-/m1/s1 BRUGTPFLMNPXDZ-PTHRTHQKSA-N 629798 US20230340011, Example 92. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629798&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311963 485657464 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341204 CC(C)CC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55NO3/c1-22(2)21-33(37)16-18-34(19-17-33)30(36)11-6-23(3)27-9-10-28-26-8-7-24-20-25(35)12-14-31(24,4)29(26)13-15-32(27,28)5/h7,22-23,25-29,35,37H,6,8-21H2,1-5H3/t23-,25+,26+,27-,28+,29+,31+,32-/m1/s1 AETOIGDOKBMGSM-PTHRTHQKSA-N 629799 US20230340011, Example 93. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629799&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312783 485657465 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341206 COC1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(5-10-28(33)31-17-13-23(34-4)14-18-31)25-8-9-26-24-7-6-21-19-22(32)11-15-29(21,2)27(24)12-16-30(25,26)3/h6,20,22-27,32H,5,7-19H2,1-4H3/t20-,22+,24+,25-,26+,27+,29+,30-/m1/s1 PIZNXHJWRVOQEE-UZKJJXDZSA-N 50465713 CHEMBL4277633::US20230340011, Example 94. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465713&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 145982460 433932978 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341208 C[C@H](CCC(=O)N1CC(C1)C(O)(C(F)(F)F)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H43F6NO3/c1-17(4-9-25(39)37-15-19(16-37)28(40,29(31,32)33)30(34,35)36)22-7-8-23-21-6-5-18-14-20(38)10-12-26(18,2)24(21)11-13-27(22,23)3/h5,17,19-24,38,40H,4,6-16H2,1-3H3/t17-,20+,21+,22-,23+,24+,26+,27-/m1/s1 HBYXXPCVEBWBLP-XCFZJUKMSA-N 629801 US20230340011, Example 97. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629801&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312463 485657467 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341210 C[C@H](CCC(=O)N1CC[C@H](C1)C(O)(C(F)(F)F)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H45F6NO3/c1-18(4-9-26(40)38-15-12-20(17-38)29(41,30(32,33)34)31(35,36)37)23-7-8-24-22-6-5-19-16-21(39)10-13-27(19,2)25(22)11-14-28(23,24)3/h5,18,20-25,39,41H,4,6-17H2,1-3H3/t18-,20-,21+,22+,23-,24+,25+,27+,28-/m1/s1 OLUVNVVHZMWWGL-RGRPLQSISA-N 629802 US20230340011, Example 98. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629802&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312541 485657468 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341920 C[C@H](CCC(=O)N1CCN(CC1)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N4O2/c1-22(5-10-30(38)36-17-15-35(16-18-36)24-20-33-34(4)21-24)27-8-9-28-26-7-6-23-19-25(37)11-13-31(23,2)29(26)12-14-32(27,28)3/h6,20-22,25-29,37H,5,7-19H2,1-4H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 WUHFAJFYONGXPH-NWKCFVCZSA-N 629916 US20230340011, Example 214.::US20230340011, Example 496. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629916&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312126 485657581 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341922 C[C@H](CCC(=O)N1CCN(CC1)c1cc(C)ns1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N3O2S/c1-21(5-10-29(37)34-15-17-35(18-16-34)30-19-22(2)33-38-30)26-8-9-27-25-7-6-23-20-24(36)11-13-31(23,3)28(25)12-14-32(26,27)4/h6,19,21,24-28,36H,5,7-18,20H2,1-4H3/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 IMCDQMKKWHIVJX-XKQUNUCNSA-N 630197 US20230340011, Example 497. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630197&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312349 485657777 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341924 CCN(C)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53N3O3/c1-6-33(5)30(38)35-19-17-34(18-20-35)29(37)12-7-22(2)26-10-11-27-25-9-8-23-21-24(36)13-15-31(23,3)28(25)14-16-32(26,27)4/h8,22,24-28,36H,6-7,9-21H2,1-5H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 HVTIQXNYTVKWHT-XJGPRUKRSA-N 629915 US20230340011, Example 213.::US20230340011, Example 498. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629915&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312363 485657580 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341926 CCN(CC)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55N3O3/c1-6-34(7-2)31(39)36-20-18-35(19-21-36)30(38)13-8-23(3)27-11-12-28-26-10-9-24-22-25(37)14-16-32(24,4)29(26)15-17-33(27,28)5/h9,23,25-29,37H,6-8,10-22H2,1-5H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 HPMPNVICONPUIN-ACBDEFBISA-N 629914 US20230340011, Example 212.::US20230340011, Example 499. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629914&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312045 485657579 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341928 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N(C)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H53N3O3/c1-22(5-12-30(38)35-17-19-36(20-18-35)31(39)34(4)24-7-8-24)27-10-11-28-26-9-6-23-21-25(37)13-15-32(23,2)29(26)14-16-33(27,28)3/h6,22,24-29,37H,5,7-21H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 FIVIYYCJLJLKHY-VEQXFWRMSA-N 629913 US20230340011, Example 211.::US20230340011, Example 500. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629913&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312288 485657578 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341930 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N(C)CC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H55N3O3/c1-23(5-12-31(39)36-17-19-37(20-18-36)32(40)35(4)22-24-6-7-24)28-10-11-29-27-9-8-25-21-26(38)13-15-33(25,2)30(27)14-16-34(28,29)3/h8,23-24,26-30,38H,5-7,9-22H2,1-4H3/t23-,26+,27+,28-,29+,30+,33+,34-/m1/s1 MEGAUYUWEKKTDG-WACGHZNISA-N 629912 US20230340011, Example 210.::US20230340011, Example 501. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629912&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312566 485657577 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341932 COCCN(C)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55N3O4/c1-23(6-11-30(38)35-16-18-36(19-17-35)31(39)34(4)20-21-40-5)27-9-10-28-26-8-7-24-22-25(37)12-14-32(24,2)29(26)13-15-33(27,28)3/h7,23,25-29,37H,6,8-22H2,1-5H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 BGNWSYUVHZOMKR-ACBDEFBISA-N 629911 US20230340011, Example 209.::US20230340011, Example 502. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629911&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312837 485657576 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341934 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51N3O3/c1-22(5-10-29(37)33-17-19-35(20-18-33)30(38)34-15-4-16-34)26-8-9-27-25-7-6-23-21-24(36)11-13-31(23,2)28(25)12-14-32(26,27)3/h6,22,24-28,36H,4-5,7-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 JPNCRCYDMGWJKV-XJGPRUKRSA-N 630203 US20230340011, Example 503. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630203&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312736 485657778 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341936 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H53N3O3/c1-23(6-11-30(38)34-18-20-36(21-19-34)31(39)35-16-4-5-17-35)27-9-10-28-26-8-7-24-22-25(37)12-14-32(24,2)29(26)13-15-33(27,28)3/h7,23,25-29,37H,4-6,8-22H2,1-3H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 XKHYNLJLTFPZKD-ACBDEFBISA-N 630204 US20230340011, Example 504. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630204&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312400 485657779 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341941 C[C@H](CCC(=O)N1CCN(CC1)c1ncncc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-22(5-10-30(39)36-15-17-37(18-16-36)31-23(2)20-34-21-35-31)27-8-9-28-26-7-6-24-19-25(38)11-13-32(24,3)29(26)12-14-33(27,28)4/h6,20-22,25-29,38H,5,7-19H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 KLDGXNMYCWCMOJ-VEQXFWRMSA-N 630208 US20230340011, Example 508. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630208&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312034 485657783 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341943 C[C@H](CCC(=O)N1CCN(CC1)c1cc(C)ncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-22(5-10-31(39)37-17-15-36(16-18-37)30-19-23(2)34-21-35-30)27-8-9-28-26-7-6-24-20-25(38)11-13-32(24,3)29(26)12-14-33(27,28)4/h6,19,21-22,25-29,38H,5,7-18,20H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 CFSUSONFVVMLHG-VEQXFWRMSA-N 629908 US20230340011, Example 206.::US20230340011, Example 509. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629908&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312750 485657573 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341945 C[C@H](CCC(=O)N1CCN(CC1)c1ccnc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-22(5-10-31(39)37-19-17-36(18-20-37)30-13-16-34-23(2)35-30)27-8-9-28-26-7-6-24-21-25(38)11-14-32(24,3)29(26)12-15-33(27,28)4/h6,13,16,22,25-29,38H,5,7-12,14-15,17-21H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 GMTRDTRPHPJYOE-VEQXFWRMSA-N 629907 US20230340011, Example 205.::US20230340011, Example 510. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629907&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312572 485657572 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341947 COc1cncnc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)36-15-17-37(18-16-36)31-29(40-4)20-34-21-35-31)26-8-9-27-25-7-6-23-19-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,20-22,24-28,38H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 LWJFQQZIYMDLDR-WKFLPMMISA-N 629906 US20230340011, Example 204.::US20230340011, Example 511. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629906&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312494 485657571 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341949 COc1cc(ncn1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-31(39)37-17-15-36(16-18-37)29-20-30(40-4)35-21-34-29)26-8-9-27-25-7-6-23-19-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,20-22,24-28,38H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 HNZMQAVQKRECOQ-WKFLPMMISA-N 629905 US20230340011, Example 203.::US20230340011, Example 512. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629905&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312918 485657570 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341951 COc1nccc(n1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)37-19-17-36(18-20-37)29-13-16-34-31(35-29)40-4)26-8-9-27-25-7-6-23-21-24(38)11-14-32(23,2)28(25)12-15-33(26,27)3/h6,13,16,22,24-28,38H,5,7-12,14-15,17-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 YJGOUXYVQXLPRP-WKFLPMMISA-N 629904 US20230340011, Example 202.::US20230340011, Example 513. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629904&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312920 485657569 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341953 C[C@H](CCC(=O)N1CCN(CC1)c1cn(C)nn1)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51N5O2/c1-21(5-10-29(38)36-17-15-35(16-18-36)28-20-34(4)33-32-28)25-8-9-26-24-7-6-22-19-23(37)11-13-30(22,2)27(24)12-14-31(25,26)3/h20-27,37H,5-19H2,1-4H3/t21-,22+,23+,24+,25-,26+,27+,30+,31-/m1/s1 HPOAUTZVGMUYAZ-JCOVCWPBSA-N 630214 US20230340011, Example 514. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630214&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312824 485657784 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341955 C[C@H](CCC(=O)N1CCN(CC1)C(=O)C1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H54N2O3/c1-23(8-13-31(38)35-18-20-36(21-19-35)32(39)24-6-4-5-7-24)28-11-12-29-27-10-9-25-22-26(37)14-16-33(25,2)30(27)15-17-34(28,29)3/h9,23-24,26-30,37H,4-8,10-22H2,1-3H3/t23-,26+,27+,28-,29+,30+,33+,34-/m1/s1 LACMMTGSKKGIAC-WACGHZNISA-N 630215 US20230340011, Example 515. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630215&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311863 485657785 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341957 C[C@H](CCC(=O)N1CCN(CC1)c1ccn(c1)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H53N3O2/c1-24(4-11-33(40)37-20-18-36(19-21-37)27-14-17-38(23-27)26-6-7-26)30-9-10-31-29-8-5-25-22-28(39)12-15-34(25,2)32(29)13-16-35(30,31)3/h5,14,17,23-24,26,28-32,39H,4,6-13,15-16,18-22H2,1-3H3/t24-,28+,29+,30-,31+,32+,34+,35-/m1/s1 VXWFMXRPEBWNHK-UAHPDCBASA-N 630216 US20230340011, Example 516. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630216&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312248 485657786 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341961 CCC1(CCCN(C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)OC InChI=1S/C32H53NO3/c1-6-32(36-5)16-7-19-33(21-32)29(35)13-8-22(2)26-11-12-27-25-10-9-23-20-24(34)14-17-30(23,3)28(25)15-18-31(26,27)4/h9,22,24-28,34H,6-8,10-21H2,1-5H3/t22-,24+,25+,26-,27+,28+,30+,31-,32?/m1/s1 OTXXDGJTOZPQFQ-ZHDSGJJZSA-N 630219 US20230340011, Example 519. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630219&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312429 485657789 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341966 C[C@H](CCC(=O)N1CCC(C)(CN2CCOC(C)(C)C2=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C37H60N2O4/c1-25(7-12-32(41)38-19-17-35(4,18-20-38)24-39-21-22-43-34(2,3)33(39)42)29-10-11-30-28-9-8-26-23-27(40)13-15-36(26,5)31(28)14-16-37(29,30)6/h8,25,27-31,40H,7,9-24H2,1-6H3/t25-,27+,28+,29-,30+,31+,36+,37-/m1/s1 LYUVEKQGTYMMPA-YBOXSPFXSA-N 630223 US20230340011, Example 523. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630223&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312867 485657793 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341212 C[C@H](CCC(=O)N1CCC(CC1)C(O)(C(F)(F)F)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H47F6NO3/c1-19(4-9-27(41)39-16-12-20(13-17-39)30(42,31(33,34)35)32(36,37)38)24-7-8-25-23-6-5-21-18-22(40)10-14-28(21,2)26(23)11-15-29(24,25)3/h5,19-20,22-26,40,42H,4,6-18H2,1-3H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 HPARTHWFELVSQS-HSIBUNQISA-N 629803 US20230340011, Example 99. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629803&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311951 485657469 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341214 C[C@H](CCC(=O)N1CC2(CC(O)C2)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H47NO3/c1-19(4-9-27(34)31-17-30(18-31)15-22(33)16-30)24-7-8-25-23-6-5-20-14-21(32)10-12-28(20,2)26(23)11-13-29(24,25)3/h5,19,21-26,32-33H,4,6-18H2,1-3H3/t19-,21+,23+,24-,25+,26+,28+,29-/m1/s1 OMPSVBCDMBPHTR-KHMNCEKASA-N 629804 US20230340011, Example 100. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629804&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312255 485657470 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341216 C[C@H](CCC(=O)N1CC2(C1)CC(C)(O)C2)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49NO3/c1-20(5-10-27(34)32-18-31(19-32)16-28(2,35)17-31)24-8-9-25-23-7-6-21-15-22(33)11-13-29(21,3)26(23)12-14-30(24,25)4/h6,20,22-26,33,35H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 YBBUNZRWJKYGQC-RFWRZFGQSA-N 629805 US20230340011, Example 101. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629805&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312182 485657471 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341218 CCC1(O)CC2(CN(C2)C(=O)CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)C1 InChI=1S/C32H51NO3/c1-5-32(36)17-31(18-32)19-33(20-31)28(35)11-6-21(2)25-9-10-26-24-8-7-22-16-23(34)12-14-29(22,3)27(24)13-15-30(25,26)4/h7,21,23-27,34,36H,5-6,8-20H2,1-4H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 GTHKKQRLTYABSE-NXUCFJMCSA-N 629806 US20230340011, Example 102. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629806&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312479 485657472 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341220 C[C@H](CCC(=O)N1CCC[C@H](O)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-19(6-11-27(33)30-16-4-5-22(32)18-30)24-9-10-25-23-8-7-20-17-21(31)12-14-28(20,2)26(23)13-15-29(24,25)3/h7,19,21-26,31-32H,4-6,8-18H2,1-3H3/t19-,21+,22+,23+,24-,25+,26+,28+,29-/m1/s1 NXJTUYJMMBKVED-AMPBYXCMSA-N 629807 US20230340011, Example 103. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629807&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312007 485657473 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341222 C[C@H](CCC(=O)N1CCC[C@@H](O)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO3/c1-19(6-11-27(33)30-16-4-5-22(32)18-30)24-9-10-25-23-8-7-20-17-21(31)12-14-28(20,2)26(23)13-15-29(24,25)3/h7,19,21-26,31-32H,4-6,8-18H2,1-3H3/t19-,21+,22-,23+,24-,25+,26+,28+,29-/m1/s1 NXJTUYJMMBKVED-BIDFFWHUSA-N 629808 US20230340011, Example 104. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629808&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312022 485657474 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341224 C[C@H](CCC(=O)N1CCC[C@@](C)(O)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(6-11-27(33)31-17-5-14-28(2,34)19-31)24-9-10-25-23-8-7-21-18-22(32)12-15-29(21,3)26(23)13-16-30(24,25)4/h7,20,22-26,32,34H,5-6,8-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,28-,29+,30-/m1/s1 YWYVTTVSSQKHBG-ZTYLRCHISA-N 629809 US20230340011, Example 105. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629809&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312451 485657475 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341226 CC[C@@]1(O)CCCN(C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51NO3/c1-5-31(35)15-6-18-32(20-31)28(34)12-7-21(2)25-10-11-26-24-9-8-22-19-23(33)13-16-29(22,3)27(24)14-17-30(25,26)4/h8,21,23-27,33,35H,5-7,9-20H2,1-4H3/t21-,23+,24+,25-,26+,27+,29+,30-,31-/m1/s1 KFCJUNUZWMIARI-AFGPTQRESA-N 629810 US20230340011, Example 106. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629810&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312085 485657476 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341231 C[C@H](CCC(=O)N1CCC[C@H](C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO2/c1-20-6-5-17-31(19-20)28(33)12-7-21(2)25-10-11-26-24-9-8-22-18-23(32)13-15-29(22,3)27(24)14-16-30(25,26)4/h8,20-21,23-27,32H,5-7,9-19H2,1-4H3/t20-,21+,23-,24-,25+,26-,27-,29-,30+/m0/s1 JLLCIWQBAWVWBU-FIILXQAHSA-N 629814 US20230340011, Example 110. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629814&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312517 485657480 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341233 C[C@H](CCC(=O)N1CCC[C@@H](C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO2/c1-20-6-5-17-31(19-20)28(33)12-7-21(2)25-10-11-26-24-9-8-22-18-23(32)13-15-29(22,3)27(24)14-16-30(25,26)4/h8,20-21,23-27,32H,5-7,9-19H2,1-4H3/t20-,21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 JLLCIWQBAWVWBU-RGRSVEPJSA-N 629815 US20230340011, Example 111. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629815&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311845 485657481 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341235 C[C@H](CCC(=O)N1CCC[C@@H]1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO2/c1-19(7-12-27(32)30-17-5-6-20(30)2)24-10-11-25-23-9-8-21-18-22(31)13-15-28(21,3)26(23)14-16-29(24,25)4/h8,19-20,22-26,31H,5-7,9-18H2,1-4H3/t19-,20+,22+,23+,24-,25+,26+,28+,29-/m1/s1 MPPMJVDCWQVOBN-NRPUAGBSSA-N 629816 US20230340011, Example 112. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629816&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312357 485657482 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341237 C[C@H](CCC(=O)N1CCC[C@H]1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO2/c1-19(7-12-27(32)30-17-5-6-20(30)2)24-10-11-25-23-9-8-21-18-22(31)13-15-28(21,3)26(23)14-16-29(24,25)4/h8,19-20,22-26,31H,5-7,9-18H2,1-4H3/t19-,20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 MPPMJVDCWQVOBN-PKCZXNRQSA-N 629817 US20230340011, Example 113. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629817&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312048 485657483 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341239 C[C@H](CCC(=O)N1CC[C@H](C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO2/c1-19-13-16-30(18-19)27(32)10-5-20(2)24-8-9-25-23-7-6-21-17-22(31)11-14-28(21,3)26(23)12-15-29(24,25)4/h6,19-20,22-26,31H,5,7-18H2,1-4H3/t19-,20+,22-,23-,24+,25-,26-,28-,29+/m0/s1 ZALMZEPNVLKONL-SWUBILCPSA-N 629818 US20230340011, Example 114. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629818&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312543 485657484 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341241 C[C@H](CCC(=O)N1CC[C@@H](C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO2/c1-19-13-16-30(18-19)27(32)10-5-20(2)24-8-9-25-23-7-6-21-17-22(31)11-14-28(21,3)26(23)12-15-29(24,25)4/h6,19-20,22-26,31H,5,7-18H2,1-4H3/t19-,20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 ZALMZEPNVLKONL-PKCZXNRQSA-N 629819 US20230340011, Example 115. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629819&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312836 485657485 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341243 C[C@H](CCC(=O)N1CC[C@H](C1)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H49NO2/c1-23(9-14-32(37)35-20-17-25(22-35)24-7-5-4-6-8-24)29-12-13-30-28-11-10-26-21-27(36)15-18-33(26,2)31(28)16-19-34(29,30)3/h4-8,10,23,25,27-31,36H,9,11-22H2,1-3H3/t23-,25-,27+,28+,29-,30+,31+,33+,34-/m1/s1 FWWZEHKSRVWMDP-PYTBKUEESA-N 629820 US20230340011, Example 116. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629820&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312301 485657486 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341245 C[C@H](CCC(=O)N1CC[C@@H](C1)c1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H49NO2/c1-23(9-14-32(37)35-20-17-25(22-35)24-7-5-4-6-8-24)29-12-13-30-28-11-10-26-21-27(36)15-18-33(26,2)31(28)16-19-34(29,30)3/h4-8,10,23,25,27-31,36H,9,11-22H2,1-3H3/t23-,25+,27+,28+,29-,30+,31+,33+,34-/m1/s1 FWWZEHKSRVWMDP-FOTOSMRYSA-N 629821 US20230340011, Example 117. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629821&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312330 485657487 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341247 C[C@@H](NC(=O)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C25H40N2O3/c1-15(26-22(29)23(30)27(4)5)19-8-9-20-18-7-6-16-14-17(28)10-12-24(16,2)21(18)11-13-25(19,20)3/h6,15,17-21,28H,7-14H2,1-5H3,(H,26,29)/t15-,17+,18+,19-,20+,21+,24+,25-/m1/s1 DXACHHGFFYWVOG-GHTHVDQMSA-N 629822 US20230340011, Example 118.::US20230340011, Example 119. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629822&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311980 485657488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341249 C[C@@H](NC(=O)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C25H40N2O3/c1-15(26-22(29)23(30)27(4)5)19-8-9-20-18-7-6-16-14-17(28)10-12-24(16,2)21(18)11-13-25(19,20)3/h6,15,17-21,28H,7-14H2,1-5H3,(H,26,29)/t15-,17+,18+,19-,20+,21+,24+,25-/m1/s1 DXACHHGFFYWVOG-GHTHVDQMSA-N 629822 US20230340011, Example 118.::US20230340011, Example 119. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629822&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311980 485657488 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341251 C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO2/c1-18(7-12-24(29)28(5)6)21-10-11-22-20-9-8-19-17-25(2,30)15-16-26(19,3)23(20)13-14-27(21,22)4/h8,18,20-23,30H,7,9-17H2,1-6H3/t18-,20+,21-,22+,23+,25+,26+,27-/m1/s1 VBJJBNUQJXNDNC-ABXCMAEBSA-N 629824 US20230340011, Example 120. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629824&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311996 485657489 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341253 C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@](C)(O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO2/c1-18(7-12-24(29)28(5)6)21-10-11-22-20-9-8-19-17-25(2,30)15-16-26(19,3)23(20)13-14-27(21,22)4/h8,18,20-23,30H,7,9-17H2,1-6H3/t18-,20+,21-,22+,23+,25-,26+,27-/m1/s1 VBJJBNUQJXNDNC-FDCDMPHRSA-N 629825 US20230340011, Example 121. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629825&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312532 485657490 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341256 C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H43NO3/c1-16(6-11-24(30)27(4)5)20-9-10-21-19-8-7-17-14-18(28)15-23(29)26(17,3)22(19)12-13-25(20,21)2/h7,16,18-23,28-29H,6,8-15H2,1-5H3/t16-,18-,19+,20-,21+,22+,23+,25-,26+/m1/s1 UXCUCAMZCMWGPB-VLRQFBLZSA-N 629827 US20230340011, Example 123. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629827&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312642 485657492 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341258 C[C@H](CCc1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO/c1-19(7-9-21-6-4-5-17-29-21)24-11-12-25-23-10-8-20-18-22(30)13-15-27(20,2)26(23)14-16-28(24,25)3/h4-6,8,17,19,22-26,30H,7,9-16,18H2,1-3H3/t19-,22+,23+,24-,25+,26+,27+,28-/m1/s1 BSOHTIRAIBGWNI-LYLGZYPGSA-N 629828 US20230340011, Example 124. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629828&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312309 485657493 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341260 C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](F)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H42FNO/c1-17(6-11-24(29)28(4)5)21-9-10-22-20-8-7-18-16-19(27)12-14-25(18,2)23(20)13-15-26(21,22)3/h7,17,19-23H,6,8-16H2,1-5H3/t17-,19+,20+,21-,22+,23+,25+,26-/m1/s1 DEEOXBUSRVAPSU-LXVLQKCJSA-N 629829 US20230340011, Example 126. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629829&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312024 485657494 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341262 C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4CC(F)(F)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H41F2NO/c1-17(6-11-23(30)29(4)5)20-9-10-21-19-8-7-18-16-26(27,28)15-14-24(18,2)22(19)12-13-25(20,21)3/h7,17,19-22H,6,8-16H2,1-5H3/t17-,19+,20-,21+,22+,24+,25-/m1/s1 GHKLSPNCKOJAEN-XCLAERPWSA-N 629830 US20230340011, Example 127. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629830&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312488 485657495 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341982 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cn(C)cn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)36-15-17-37(18-16-36)31(40)29-20-35(4)21-34-29)26-8-9-27-25-7-6-23-19-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,20-22,24-28,38H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 QYMBTKSOBWAAKD-WKFLPMMISA-N 630238 US20230340011, Example 538. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630238&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312053 485657807 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341984 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ccn(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)36-17-19-37(20-18-36)31(40)29-13-16-35(4)34-29)26-8-9-27-25-7-6-23-21-24(38)11-14-32(23,2)28(25)12-15-33(26,27)3/h6,13,16,22,24-28,38H,5,7-12,14-15,17-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 HORYJAIDKWEWCS-WKFLPMMISA-N 630239 US20230340011, Example 539. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630239&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312932 485657808 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341986 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1nnc(C)o1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O4/c1-20(5-10-28(38)35-15-17-36(18-16-35)30(39)29-34-33-21(2)40-29)25-8-9-26-24-7-6-22-19-23(37)11-13-31(22,3)27(24)12-14-32(25,26)4/h6,20,23-27,37H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,31+,32-/m1/s1 RFNCXUNBXUHPHW-LDQJSCHESA-N 630240 US20230340011, Example 540. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630240&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312492 485657809 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341990 C[C@H](CCC(=O)N(C)CCc1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N2O2/c1-22(7-12-30(36)34(4)19-15-23-6-5-18-33-21-23)27-10-11-28-26-9-8-24-20-25(35)13-16-31(24,2)29(26)14-17-32(27,28)3/h5-6,8,18,21-22,25-29,35H,7,9-17,19-20H2,1-4H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 FFVUWWDAZAEMFG-NWKCFVCZSA-N 630243 US20230340011, Example 543. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630243&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312188 485657812 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341993 C[C@H](CCC(=O)N(C)CCc1nccs1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H46N2O2S/c1-20(5-10-28(34)32(4)17-13-27-31-16-18-35-27)24-8-9-25-23-7-6-21-19-22(33)11-14-29(21,2)26(23)12-15-30(24,25)3/h6,16,18,20,22-26,33H,5,7-15,17,19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 NTBVUTYGWSXDHU-RFWRZFGQSA-N 630245 US20230340011, Example 545. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630245&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312300 485657814 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341995 C[C@H](CCC(=O)N1CCC(CC1)OCc1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N2O3/c1-24(4-9-33(39)37-20-14-28(15-21-37)40-23-25-12-18-36-19-13-25)30-7-8-31-29-6-5-26-22-27(38)10-16-34(26,2)32(29)11-17-35(30,31)3/h5,12-13,18-19,24,27-32,38H,4,6-11,14-17,20-23H2,1-3H3/t24-,27+,29+,30-,31+,32+,34+,35-/m1/s1 QWSNOGOEEIWHOS-HQNYHPTBSA-N 630246 US20230340011, Example 546. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630246&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312087 485657815 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341998 C[C@H](CCC(=O)N(C1CC1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H46N2O2/c1-21(4-11-30(36)34(23-6-7-23)24-14-18-33-19-15-24)27-9-10-28-26-8-5-22-20-25(35)12-16-31(22,2)29(26)13-17-32(27,28)3/h5,14-15,18-19,21,23,25-29,35H,4,6-13,16-17,20H2,1-3H3/t21-,25+,26+,27-,28+,29+,31+,32-/m1/s1 FKVVKQNEEGIOHR-KNLNLFKVSA-N 630248 US20230340011, Example 548. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630248&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312241 485657817 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342001 COC(=O)N1CCN(CC1)C(=S)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N2O3S/c1-20(5-10-27(36)31-15-17-32(18-16-31)28(34)35-4)24-8-9-25-23-7-6-21-19-22(33)11-13-29(21,2)26(23)12-14-30(24,25)3/h6,20,22-26,33H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 BZRNNXACZWYIFG-RFWRZFGQSA-N 630250 US20230340011, Example 550. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630250&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312402 485657819 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342003 CSC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N2O3S/c1-20(5-10-27(34)31-15-17-32(18-16-31)28(35)36-4)24-8-9-25-23-7-6-21-19-22(33)11-13-29(21,2)26(23)12-14-30(24,25)3/h6,20,22-26,33H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 HFTXBKOTABAZCF-RFWRZFGQSA-N 630251 US20230340011, Example 551. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630251&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312104 485657820 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342005 COC(=O)N1CCC11CN(C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N2O4/c1-20(5-10-27(35)32-18-31(19-32)15-16-33(31)28(36)37-4)24-8-9-25-23-7-6-21-17-22(34)11-13-29(21,2)26(23)12-14-30(24,25)3/h6,20,22-26,34H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 ULAKAYKFQSRJQR-RFWRZFGQSA-N 630252 US20230340011, Example 552. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630252&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312876 485657821 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342007 COC(=O)N1CCSC11CN(C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N2O4S/c1-20(5-10-27(35)32-18-31(19-32)33(15-16-38-31)28(36)37-4)24-8-9-25-23-7-6-21-17-22(34)11-13-29(21,2)26(23)12-14-30(24,25)3/h6,20,22-26,34H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 WDQWQVTYCRMQGQ-RFWRZFGQSA-N 630253 US20230340011, Example 553. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630253&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312718 485657822 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342009 COC(=O)N1CCC2(CCN(C2)C(=O)CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)C1 InChI=1S/C33H52N2O4/c1-22(5-10-29(37)34-17-15-33(20-34)16-18-35(21-33)30(38)39-4)26-8-9-27-25-7-6-23-19-24(36)11-13-31(23,2)28(25)12-14-32(26,27)3/h6,22,24-28,36H,5,7-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,31+,32-,33?/m1/s1 FMAVWJAXICGULS-OHNZCGRCSA-N 630254 US20230340011, Example 554. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630254&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312559 485657823 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342011 C[C@H](CCC(=O)Nc1ccc(NC(C)=O)cc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H46N2O3/c1-20(5-14-30(37)34-24-9-7-23(8-10-24)33-21(2)35)27-12-13-28-26-11-6-22-19-25(36)15-17-31(22,3)29(26)16-18-32(27,28)4/h6-10,20,25-29,36H,5,11-19H2,1-4H3,(H,33,35)(H,34,37)/t20-,25+,26+,27-,28+,29+,31+,32-/m1/s1 BYBBOMXWMNNVBN-KIKWYLJFSA-N 630255 US20230340011, Example 555. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630255&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312787 485657824 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342014 C[C@H](CCC(=O)N1CCN(CC1)C(C)(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H54N2O2/c1-22(7-12-29(36)33-17-19-34(20-18-33)30(2,3)4)26-10-11-27-25-9-8-23-21-24(35)13-15-31(23,5)28(25)14-16-32(26,27)6/h8,22,24-28,35H,7,9-21H2,1-6H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 NMHHDNIEAAPADA-XJGPRUKRSA-N 630257 US20230340011, Example 557. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630257&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312759 485657826 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342017 C[C@H](CCC(=O)N1CCN(CC1)c1ccnc(O)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O3/c1-21(4-9-29(38)36-18-16-35(17-19-36)28-12-15-33-30(39)34-28)25-7-8-26-24-6-5-22-20-23(37)10-13-31(22,2)27(24)11-14-32(25,26)3/h5,12,15,21,23-27,37H,4,6-11,13-14,16-20H2,1-3H3,(H,33,34,39)/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 MKJFWQWAMPGBGP-GTORSBDHSA-N 630259 US20230340011, Example 559. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630259&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312919 485657828 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342019 C[C@H](CCC(=O)N1CCN(CC1)c1ccnc(N)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N5O2/c1-21(4-9-29(39)37-18-16-36(17-19-37)28-12-15-34-30(33)35-28)25-7-8-26-24-6-5-22-20-23(38)10-13-31(22,2)27(24)11-14-32(25,26)3/h5,12,15,21,23-27,38H,4,6-11,13-14,16-20H2,1-3H3,(H2,33,34,35)/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 WIOZDPOAANJRRU-GTORSBDHSA-N 630260 US20230340011, Example 560. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630260&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312411 485657829 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341264 C[C@H](CCC(=O)N1CCC(O)(CC1)C(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H47F2NO3/c1-19(4-9-26(35)33-16-14-30(36,15-17-33)27(31)32)23-7-8-24-22-6-5-20-18-21(34)10-12-28(20,2)25(22)11-13-29(23,24)3/h5,19,21-25,27,34,36H,4,6-18H2,1-3H3/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 QRCKSIDYJUQFBB-YIZNBMETSA-N 629831 US20230340011, Example 128. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629831&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312125 485657496 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341266 CCC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51NO3/c1-5-31(35)16-18-32(19-17-31)28(34)11-6-21(2)25-9-10-26-24-8-7-22-20-23(33)12-14-29(22,3)27(24)13-15-30(25,26)4/h7,21,23-27,33,35H,5-6,8-20H2,1-4H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 XCIASCLPGRSRQB-NXUCFJMCSA-N 629832 US20230340011, Example 129. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629832&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312730 485657497 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341268 O.C[C@H](CCc1ncccc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H43NO.H2O/c1-19(7-12-27-20(2)6-5-17-30-27)24-10-11-25-23-9-8-21-18-22(31)13-15-28(21,3)26(23)14-16-29(24,25)4;/h5-6,8,17,19,22-26,31H,7,9-16,18H2,1-4H3;1H2/t19-,22+,23+,24-,25+,26+,28+,29-;/m1./s1 HEIKHFHQYUGOTH-GQXJMFBVSA-N 629833 US20230340011, Example 130. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629833&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169490210 485657498 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341270 C[C@H](CCc1ccc(C)cn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H43NO/c1-19-5-8-22(30-18-19)9-6-20(2)25-11-12-26-24-10-7-21-17-23(31)13-15-28(21,3)27(24)14-16-29(25,26)4/h5,7-8,18,20,23-27,31H,6,9-17H2,1-4H3/t20-,23+,24+,25-,26+,27+,28+,29-/m1/s1 IQMOVRQEXIPYAP-VEVYEIKRSA-N 629834 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-4-(5-methylpyridin-2-yl)butan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol::US20230340011, Example 131. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629834&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312808 485657499 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341272 C[C@H](\C=C\c1cccc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H41NO/c1-19(8-10-22-7-5-6-20(2)30-22)25-12-13-26-24-11-9-21-18-23(31)14-16-28(21,3)27(24)15-17-29(25,26)4/h5-10,19,23-27,31H,11-18H2,1-4H3/b10-8+/t19-,23+,24+,25-,26+,27+,28+,29-/m1/s1 TZUADTUVEYZNOH-DUYRDQBQSA-N 629835 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-4-(6-methylpyridin-2-yl)butan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol::US20230340011, Example 132. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629835&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169490211 485657500 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341274 C[C@H](CCc1ncccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H40N2O/c1-18(5-10-25-28-15-4-16-29-25)22-8-9-23-21-7-6-19-17-20(30)11-13-26(19,2)24(21)12-14-27(22,23)3/h4,6,15-16,18,20-24,30H,5,7-14,17H2,1-3H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 LHFCOLNAXRQVGB-ZHHJOTBYSA-N 629836 (1R,3aS,3bS,7S,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-4-(pyrimidin-2-yl)butan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-ol::US20230340011, Example 133. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629836&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312425 485657501 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341276 C[C@H](CCc1cccnn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H40N2O/c1-18(6-8-20-5-4-16-28-29-20)23-10-11-24-22-9-7-19-17-21(30)12-14-26(19,2)25(22)13-15-27(23,24)3/h4-5,7,16,18,21-25,30H,6,8-15,17H2,1-3H3/t18-,21+,22+,23-,24+,25+,26+,27-/m1/s1 QLUYQTPUCLHVJM-NVVJDQLXSA-N 629837 US20230340011, Example 134. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629837&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312265 485657502 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341278 C[C@H](CCc1cccnn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H40N2O/c1-18(6-8-20-5-4-16-28-29-20)23-10-11-24-22-9-7-19-17-21(30)12-14-26(19,2)25(22)13-15-27(23,24)3/h4-5,7,16,18,21-25,30H,6,8-15,17H2,1-3H3/t18-,21+,22+,23-,24+,25+,26+,27-/m1/s1 QLUYQTPUCLHVJM-NVVJDQLXSA-N 629838 (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-4-(pyrimidin-4-yl)butan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol::US20230340011, Example 135. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629838&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312265 485657503 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341280 C[C@H](CCc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H40N2O/c1-18(4-6-20-12-15-28-17-29-20)23-8-9-24-22-7-5-19-16-21(30)10-13-26(19,2)25(22)11-14-27(23,24)3/h5,12,15,17-18,21-25,30H,4,6-11,13-14,16H2,1-3H3/t18-,21+,22+,23-,24+,25+,26+,27-/m1/s1 TYKCEKYAWKWNNZ-NVVJDQLXSA-N 629839 US20230340011, Example 136. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629839&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312593 485657504 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341282 C[C@H](CCc1ncco1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H39NO2/c1-17(4-9-24-27-14-15-29-24)21-7-8-22-20-6-5-18-16-19(28)10-12-25(18,2)23(20)11-13-26(21,22)3/h5,14-15,17,19-23,28H,4,6-13,16H2,1-3H3/t17-,19+,20+,21-,22+,23+,25+,26-/m1/s1 GULTWYFLGMFPQJ-LXVLQKCJSA-N 629840 US20230340011, Example 137. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629840&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312077 485657505 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341283 C[C@H](CCC(=O)N1CC(C)(C)[C@@H]2COC[C@H]12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51NO3/c1-20(6-11-29(35)33-19-30(2,3)27-17-36-18-28(27)33)24-9-10-25-23-8-7-21-16-22(34)12-14-31(21,4)26(23)13-15-32(24,25)5/h7,20,22-28,34H,6,8-19H2,1-5H3/t20-,22+,23+,24-,25+,26+,27-,28+,31+,32-/m1/s1 JQTDLDLXTBIQMI-YFUQXCKCSA-N 629841 US20230340011, Example 138. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629841&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312856 485657506 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341285 C[C@H](CCC(=O)N1CC[C@H]2CN(CC=C)C[C@@H]12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N2O2/c1-5-17-34-20-23-14-18-35(30(23)21-34)31(37)11-6-22(2)27-9-10-28-26-8-7-24-19-25(36)12-15-32(24,3)29(26)13-16-33(27,28)4/h5,7,22-23,25-30,36H,1,6,8-21H2,2-4H3/t22-,23+,25+,26+,27-,28+,29+,30-,32+,33-/m1/s1 MQNYLJIJWGOTKI-IEZXLMHBSA-N 629842 US20230340011, Example 139. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629842&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312904 485657507 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341287 C[C@H](CCC(=O)N1CC[C@@H]2CN(CC=C)C[C@H]12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N2O2/c1-5-17-34-20-23-14-18-35(30(23)21-34)31(37)11-6-22(2)27-9-10-28-26-8-7-24-19-25(36)12-15-32(24,3)29(26)13-16-33(27,28)4/h5,7,22-23,25-30,36H,1,6,8-21H2,2-4H3/t22-,23-,25+,26+,27-,28+,29+,30+,32+,33-/m1/s1 MQNYLJIJWGOTKI-DXIRPJGISA-N 629843 US20230340011, Example 140. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629843&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312803 485657508 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341288 CON(C)C(=O)[C@H](C)C[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO3/c1-17(15-18(2)25(30)28(5)31-6)22-9-10-23-21-8-7-19-16-20(29)11-13-26(19,3)24(21)12-14-27(22,23)4/h7,17-18,20-24,29H,8-16H2,1-6H3/t17-,18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 JKPRVLUKHDMLES-KQOPCUSDSA-N 629844 US20230340011, Example 141. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629844&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312107 485657509 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341290 CON(C)C(=O)[C@@H](C)C[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO3/c1-17(15-18(2)25(30)28(5)31-6)22-9-10-23-21-8-7-19-16-20(29)11-13-26(19,3)24(21)12-14-27(22,23)4/h7,17-18,20-24,29H,8-16H2,1-6H3/t17-,18+,20+,21+,22-,23+,24+,26+,27-/m1/s1 JKPRVLUKHDMLES-DDMWTQRYSA-N 629845 US20230340011, Example 142. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629845&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312208 485657510 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341291 C[C@H](OC(=O)CN(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C25H41NO3/c1-16(29-23(28)15-26(4)5)20-8-9-21-19-7-6-17-14-18(27)10-12-24(17,2)22(19)11-13-25(20,21)3/h6,16,18-22,27H,7-15H2,1-5H3/t16-,18-,19-,20+,21-,22-,24-,25+/m0/s1 BDONYZYGDALATG-INAYBBMBSA-N 629846 (S)-1-((3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethyl dimethylglycinate::US20230340011, Example 143. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629846&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312106 485657511 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341292 C[C@H](OC(=O)C(N)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C23H35NO4/c1-13(28-21(27)20(24)26)17-6-7-18-16-5-4-14-12-15(25)8-10-22(14,2)19(16)9-11-23(17,18)3/h4,13,15-19,25H,5-12H2,1-3H3,(H2,24,26)/t13-,15-,16-,17+,18-,19-,22-,23+/m0/s1 YKUDWDHERIPYRZ-VJGYNNPDSA-N 629847 US20230340011, Example 144. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629847&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312516 485657512 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341293 CNC(=O)C(=O)O[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C24H37NO4/c1-14(29-22(28)21(27)25-4)18-7-8-19-17-6-5-15-13-16(26)9-11-23(15,2)20(17)10-12-24(18,19)3/h5,14,16-20,26H,6-13H2,1-4H3,(H,25,27)/t14-,16-,17-,18+,19-,20-,23-,24+/m0/s1 KFOHFKGNIIMIRX-RRGSWWRUSA-N 629848 US20230340011, Example 145. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629848&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312097 485657513 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341295 C[C@H](CCC(=O)N1CCC(O)(CC1)C=C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49NO3/c1-5-31(35)16-18-32(19-17-31)28(34)11-6-21(2)25-9-10-26-24-8-7-22-20-23(33)12-14-29(22,3)27(24)13-15-30(25,26)4/h5,7,21,23-27,33,35H,1,6,8-20H2,2-4H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 SRDMAHSGPGXUOC-NXUCFJMCSA-N 629849 US20230340011, Example 146. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629849&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312207 485657514 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341297 C[C@H](CCC(=O)N1CCC(O)(CC1)C#C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H47NO3/c1-5-31(35)16-18-32(19-17-31)28(34)11-6-21(2)25-9-10-26-24-8-7-22-20-23(33)12-14-29(22,3)27(24)13-15-30(25,26)4/h1,7,21,23-27,33,35H,6,8-20H2,2-4H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1 KSMGMDVHOFLAFH-NXUCFJMCSA-N 629850 US20230340011, Example 147. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629850&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312578 485657515 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341299 CCCC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53NO3/c1-5-14-32(36)17-19-33(20-18-32)29(35)11-6-22(2)26-9-10-27-25-8-7-23-21-24(34)12-15-30(23,3)28(25)13-16-31(26,27)4/h7,22,24-28,34,36H,5-6,8-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,30+,31-/m1/s1 SDRAOTAIGRLMCD-GTPODGLVSA-N 629851 US20230340011, Example 148. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629851&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312539 485657516 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341301 C[C@H](CCC(=O)N1CCC(O)(CC1)C(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53NO3/c1-21(2)32(36)16-18-33(19-17-32)29(35)11-6-22(3)26-9-10-27-25-8-7-23-20-24(34)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,21-22,24-28,34,36H,6,8-20H2,1-5H3/t22-,24+,25+,26-,27+,28+,30+,31-/m1/s1 GFYAONIZMGHILK-GTPODGLVSA-N 629852 US20230340011, Example 149. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629852&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311865 485657517 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341303 C[C@H](CCC(=O)N1CCC(O)(CO)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO4/c1-20(4-9-27(34)31-16-14-30(35,19-32)15-17-31)24-7-8-25-23-6-5-21-18-22(33)10-12-28(21,2)26(23)11-13-29(24,25)3/h5,20,22-26,32-33,35H,4,6-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 BZNZTFPVHCRTIJ-OHPSOFBHSA-N 629853 US20230340011, Example 150. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629853&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312911 485657518 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341305 C[C@H](CCC(=O)N1CCC(O)(CC(F)F)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49F2NO3/c1-20(4-9-28(36)34-16-14-31(37,15-17-34)19-27(32)33)24-7-8-25-23-6-5-21-18-22(35)10-12-29(21,2)26(23)11-13-30(24,25)3/h5,20,22-27,35,37H,4,6-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 BFQFGSRUGHCILX-RFWRZFGQSA-N 629854 US20230340011, Example 151. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629854&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312788 485657519 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341307 C[C@H](CCC(=O)N1CCC(O)(CC(F)(F)F)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48F3NO3/c1-20(4-9-27(37)35-16-14-30(38,15-17-35)19-31(32,33)34)24-7-8-25-23-6-5-21-18-22(36)10-12-28(21,2)26(23)11-13-29(24,25)3/h5,20,22-26,36,38H,4,6-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 YUVUADPRHHCDCU-OHPSOFBHSA-N 629855 US20230340011, Example 152. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629855&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312245 485657520 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341309 CCN(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO2/c1-6-28(5)25(30)12-7-18(2)22-10-11-23-21-9-8-19-17-20(29)13-15-26(19,3)24(21)14-16-27(22,23)4/h8,18,20-24,29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 UIVYMANQVISZNZ-ZHHJOTBYSA-N 50509895 CHEMBL4538857::US20230340011, Example 153. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509895&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 155548820 440718480 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341311 CCN(CC)C(=O)C(=O)O[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H43NO4/c1-6-28(7-2)24(30)25(31)32-17(3)21-10-11-22-20-9-8-18-16-19(29)12-14-26(18,4)23(20)13-15-27(21,22)5/h8,17,19-23,29H,6-7,9-16H2,1-5H3/t17-,19-,20-,21+,22-,23-,26-,27+/m0/s1 NIOWYZWIYTYWKD-GSXUXVAXSA-N 629857 US20230340011, Example 154. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629857&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312826 485657522 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341313 C[C@H](OC(=O)C(=O)N1CCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H39NO4/c1-16(31-24(30)23(29)27-13-4-14-27)20-7-8-21-19-6-5-17-15-18(28)9-11-25(17,2)22(19)10-12-26(20,21)3/h5,16,18-22,28H,4,6-15H2,1-3H3/t16-,18-,19-,20+,21-,22-,25-,26+/m0/s1 RCTFTKXXLWHCMF-MYXKBYKWSA-N 629858 US20230340011, Example 155. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629858&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312392 485657523 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342021 CNc1nccc(n1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H51N5O2/c1-22(5-10-30(40)38-19-17-37(18-20-38)29-13-16-35-31(34-4)36-29)26-8-9-27-25-7-6-23-21-24(39)11-14-32(23,2)28(25)12-15-33(26,27)3/h6,13,16,22,24-28,39H,5,7-12,14-15,17-21H2,1-4H3,(H,34,35,36)/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 NYYMJJMYYMLUEB-WKFLPMMISA-N 630261 US20230340011, Example 561. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630261&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311879 485657830 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342023 C[C@H](CCC(=O)N1CCN(CC1)c1ccnc(n1)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H53N5O2/c1-23(6-11-31(41)39-20-18-38(19-21-39)30-14-17-35-32(36-30)37(4)5)27-9-10-28-26-8-7-24-22-25(40)12-15-33(24,2)29(26)13-16-34(27,28)3/h7,14,17,23,25-29,40H,6,8-13,15-16,18-22H2,1-5H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 CNONPXBSYOFGSW-NVYQQUOZSA-N 630262 US20230340011, Example 562. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630262&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312512 485657831 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342025 CCOc1nccc(n1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O3/c1-5-41-32-35-17-14-30(36-32)37-18-20-38(21-19-37)31(40)11-6-23(2)27-9-10-28-26-8-7-24-22-25(39)12-15-33(24,3)29(26)13-16-34(27,28)4/h7,14,17,23,25-29,39H,5-6,8-13,15-16,18-22H2,1-4H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 QAOKZJOIBOQNDB-NVYQQUOZSA-N 630263 US20230340011, Example 563. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630263&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312663 485657832 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342027 C[C@H](CCC(=O)N1CCN(CC1)c1ccnc(OCCO)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O4/c1-23(4-9-31(41)38-18-16-37(17-19-38)30-12-15-35-32(36-30)42-21-20-39)27-7-8-28-26-6-5-24-22-25(40)10-13-33(24,2)29(26)11-14-34(27,28)3/h5,12,15,23,25-29,39-40H,4,6-11,13-14,16-22H2,1-3H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 AQVIKKGDSQFSKP-NVYQQUOZSA-N 630264 US20230340011, Example 564. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630264&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312342 485657833 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342029 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)36-15-17-37(18-16-36)31(40)23-20-34-35(4)21-23)27-8-9-28-26-7-6-24-19-25(38)11-13-32(24,2)29(26)12-14-33(27,28)3/h6,20-22,25-29,38H,5,7-19H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 DQGMTMJCVJHZGV-VEQXFWRMSA-N 630010 US20230340011, Example 309.::US20230340011, Example 392.::US20230340011, Example 565. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312775 485657674 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342031 COC(=O)N1CCN(C[C@@H]1C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O4/c1-20(6-11-28(35)32-16-17-33(21(2)19-32)29(36)37-5)25-9-10-26-24-8-7-22-18-23(34)12-14-30(22,3)27(24)13-15-31(25,26)4/h7,20-21,23-27,34H,6,8-19H2,1-5H3/t20-,21+,23+,24+,25-,26+,27+,30+,31-/m1/s1 DRYICMPQRVAFDR-HGICBTARSA-N 630266 US20230340011, Example 566. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630266&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311904 485657834 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342033 C[C@H](CCC(=O)N1CCN(C(C)C1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O2/c1-23(5-10-32(39)36-19-20-37(24(2)22-36)26-13-17-35-18-14-26)29-8-9-30-28-7-6-25-21-27(38)11-15-33(25,3)31(28)12-16-34(29,30)4/h6,13-14,17-18,23-24,27-31,38H,5,7-12,15-16,19-22H2,1-4H3/t23-,24?,27+,28+,29-,30+,31+,33+,34-/m1/s1 YQHODCUCVFLCLU-FNQPGAMWSA-N 630267 US20230340011, Example 567. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630267&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312271 485657835 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342035 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)c1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N4O3/c1-22(5-10-31(40)37-17-18-38(23(2)21-37)32(41)30-20-35-15-16-36-30)27-8-9-28-26-7-6-24-19-25(39)11-13-33(24,3)29(26)12-14-34(27,28)4/h6,15-16,20,22-23,25-29,39H,5,7-14,17-19,21H2,1-4H3/t22-,23+,25+,26+,27-,28+,29+,33+,34-/m1/s1 DGQJQDWDBNWIJY-KDUNHSFTSA-N 630268 US20230340011, Example 568. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630268&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312409 485657836 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342037 CCC(=O)N1CCN(C[C@@H]1C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-6-29(36)34-18-17-33(20-22(34)3)30(37)12-7-21(2)26-10-11-27-25-9-8-23-19-24(35)13-15-31(23,4)28(25)14-16-32(26,27)5/h8,21-22,24-28,35H,6-7,9-20H2,1-5H3/t21-,22+,24+,25+,26-,27+,28+,31+,32-/m1/s1 SUCACOFZNRHYLW-WZFWJUJTSA-N 630269 US20230340011, Example 569. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630269&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312417 485657837 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342039 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)OC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N2O4/c1-21(5-12-30(37)34-17-18-35(22(2)20-34)31(38)39-25-7-8-25)27-10-11-28-26-9-6-23-19-24(36)13-15-32(23,3)29(26)14-16-33(27,28)4/h6,21-22,24-29,36H,5,7-20H2,1-4H3/t21-,22+,24+,26+,27-,28+,29+,32+,33-/m1/s1 KNTLCRWTLWOUQC-WIILPMAQSA-N 630270 US20230340011, Example 570. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630270&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312005 485657838 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342041 C[C@H](CCC(=O)N1CC[C@H](Oc2ccncc2)[C@@H](C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N2O3/c1-23(5-10-33(39)37-20-15-32(24(2)22-37)40-27-13-18-36-19-14-27)29-8-9-30-28-7-6-25-21-26(38)11-16-34(25,3)31(28)12-17-35(29,30)4/h6,13-14,18-19,23-24,26,28-32,38H,5,7-12,15-17,20-22H2,1-4H3/t23-,24+,26+,28+,29-,30+,31+,32+,34+,35-/m1/s1 KNFPZWRZHWTNCJ-QSFONYSASA-N 630032 US20230340011, Example 571. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630032&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311854 485657696 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342043 C[C@H](CCC(=O)N1CC[C@@H](Oc2ccncc2)[C@@H](C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N2O3/c1-23(5-10-33(39)37-20-15-32(24(2)22-37)40-27-13-18-36-19-14-27)29-8-9-30-28-7-6-25-21-26(38)11-16-34(25,3)31(28)12-17-35(29,30)4/h6,13-14,18-19,23-24,26,28-32,38H,5,7-12,15-17,20-22H2,1-4H3/t23-,24+,26+,28+,29-,30+,31+,32-,34+,35-/m1/s1 KNFPZWRZHWTNCJ-YOUQCVEUSA-N 630272 US20230340011, Example 572. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630272&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312810 485657840 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342045 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53N3O3/c1-21(7-12-29(37)34-17-18-35(22(2)20-34)30(38)33(5)6)26-10-11-27-25-9-8-23-19-24(36)13-15-31(23,3)28(25)14-16-32(26,27)4/h8,21-22,24-28,36H,7,9-20H2,1-6H3/t21-,22+,24+,25+,26-,27+,28+,31+,32-/m1/s1 HMQIZLVXMOKLDU-WZFWJUJTSA-N 630273 US20230340011, Example 573. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630273&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312825 485657841 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342047 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)c1cn(C)nn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H51N5O3/c1-21(6-11-30(40)37-16-17-38(22(2)19-37)31(41)29-20-36(5)35-34-29)26-9-10-27-25-8-7-23-18-24(39)12-14-32(23,3)28(25)13-15-33(26,27)4/h7,20-22,24-28,39H,6,8-19H2,1-5H3/t21-,22+,24+,25+,26-,27+,28+,32+,33-/m1/s1 UIYQFBOQDCCMCR-PACBQIDMSA-N 630274 US20230340011, Example 574. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630274&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312050 485657842 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342049 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)c1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-22(5-10-31(39)36-17-18-37(23(2)20-36)30-13-16-34-21-35-30)27-8-9-28-26-7-6-24-19-25(38)11-14-32(24,3)29(26)12-15-33(27,28)4/h6,13,16,21-23,25-29,38H,5,7-12,14-15,17-20H2,1-4H3/t22-,23+,25+,26+,27-,28+,29+,32+,33-/m1/s1 OEWKSQUPGVGDFK-GBHBUJJPSA-N 630275 US20230340011, Example 575. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630275&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312173 485657843 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342051 CC(C)OC(=O)N1CCN(C[C@@H]1C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H54N2O4/c1-21(2)39-31(38)35-18-17-34(20-23(35)4)30(37)12-7-22(3)27-10-11-28-26-9-8-24-19-25(36)13-15-32(24,5)29(26)14-16-33(27,28)6/h8,21-23,25-29,36H,7,9-20H2,1-6H3/t22-,23+,25+,26+,27-,28+,29+,32+,33-/m1/s1 KIABVAXMQSBTHD-GBHBUJJPSA-N 630276 US20230340011, Example 576. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630276&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311971 485657844 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342053 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H51N3O3/c1-23(5-10-32(40)37-19-20-38(24(2)22-37)33(41)25-13-17-36-18-14-25)29-8-9-30-28-7-6-26-21-27(39)11-15-34(26,3)31(28)12-16-35(29,30)4/h6,13-14,17-18,23-24,27-31,39H,5,7-12,15-16,19-22H2,1-4H3/t23-,24+,27+,28+,29-,30+,31+,34+,35-/m1/s1 STEYRNUXENTCLT-XGEGFHRISA-N 630277 US20230340011, Example 577. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630277&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312873 485657845 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342055 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O3/c1-22(6-11-31(40)38-17-16-37(20-23(38)2)32(41)24-19-35-36(5)21-24)28-9-10-29-27-8-7-25-18-26(39)12-14-33(25,3)30(27)13-15-34(28,29)4/h7,19,21-23,26-30,39H,6,8-18,20H2,1-5H3/t22-,23+,26+,27+,28-,29+,30+,33+,34-/m1/s1 ZIDRQPQRZOFOSS-RCZZVTCRSA-N 630278 US20230340011, Example 578. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630278&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312138 485657846 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342057 COC(=O)N1CCN([C@@H](C)C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O4/c1-20(6-11-28(35)33-17-16-32(19-21(33)2)29(36)37-5)25-9-10-26-24-8-7-22-18-23(34)12-14-30(22,3)27(24)13-15-31(25,26)4/h7,20-21,23-27,34H,6,8-19H2,1-5H3/t20-,21+,23+,24+,25-,26+,27+,30+,31-/m1/s1 MDLJWALKSQEJOM-HGICBTARSA-N 630279 US20230340011, Example 579. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630279&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312647 485657847 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342059 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O2/c1-23(5-10-32(39)37-20-19-36(22-24(37)2)26-13-17-35-18-14-26)29-8-9-30-28-7-6-25-21-27(38)11-15-33(25,3)31(28)12-16-34(29,30)4/h6,13-14,17-18,23-24,27-31,38H,5,7-12,15-16,19-22H2,1-4H3/t23-,24+,27+,28+,29-,30+,31+,33+,34-/m1/s1 YGGJBKMMFMLTKI-QIWKHXGQSA-N 630280 US20230340011, Example 580. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630280&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311895 485657848 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342061 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)c1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N4O3/c1-22(5-10-31(40)38-18-17-37(21-23(38)2)32(41)30-20-35-15-16-36-30)27-8-9-28-26-7-6-24-19-25(39)11-13-33(24,3)29(26)12-14-34(27,28)4/h6,15-16,20,22-23,25-29,39H,5,7-14,17-19,21H2,1-4H3/t22-,23+,25+,26+,27-,28+,29+,33+,34-/m1/s1 WVQCPTYAGHQORZ-KDUNHSFTSA-N 630281 US20230340011, Example 581. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630281&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312171 485657849 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342063 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53N3O3/c1-21(7-12-29(37)35-18-17-34(20-22(35)2)30(38)33(5)6)26-10-11-27-25-9-8-23-19-24(36)13-15-31(23,3)28(25)14-16-32(26,27)4/h8,21-22,24-28,36H,7,9-20H2,1-6H3/t21-,22+,24+,25+,26-,27+,28+,31+,32-/m1/s1 CXUAVALDCVYSTD-WZFWJUJTSA-N 630282 US20230340011, Example 582. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630282&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312145 485657850 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342065 CCC(=O)N1CCN([C@@H](C)C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-6-29(36)33-17-18-34(22(3)20-33)30(37)12-7-21(2)26-10-11-27-25-9-8-23-19-24(35)13-15-31(23,4)28(25)14-16-32(26,27)5/h8,21-22,24-28,35H,6-7,9-20H2,1-5H3/t21-,22+,24+,25+,26-,27+,28+,31+,32-/m1/s1 WKWFPIDXESGDHV-WZFWJUJTSA-N 630283 US20230340011, Example 583. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630283&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312712 485657851 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342067 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)OC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N2O4/c1-21(5-12-30(37)35-18-17-34(20-22(35)2)31(38)39-25-7-8-25)27-10-11-28-26-9-6-23-19-24(36)13-15-32(23,3)29(26)14-16-33(27,28)4/h6,21-22,24-29,36H,5,7-20H2,1-4H3/t21-,22+,24+,26+,27-,28+,29+,32+,33-/m1/s1 DHHXDXXYQCXEKP-WIILPMAQSA-N 630284 US20230340011, Example 584. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630284&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311881 485657852 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342069 C[C@H](CCC(=O)N1CC[C@@H](C[C@@H]1C)Oc1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N2O3/c1-23(5-10-33(39)37-20-15-28(21-24(37)2)40-27-13-18-36-19-14-27)30-8-9-31-29-7-6-25-22-26(38)11-16-34(25,3)32(29)12-17-35(30,31)4/h6,13-14,18-19,23-24,26,28-32,38H,5,7-12,15-17,20-22H2,1-4H3/t23-,24+,26+,28+,29+,30-,31+,32+,34+,35-/m1/s1 IPPYYXSCJCJYNM-AOKDZXKESA-N 630285 (R)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1-((2S,4S)-2-methyl-4-(pyridin-4-yloxy)piperidin-1-yl)pentan-1-one::US20230340011, Example 585. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630285&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312645 485657853 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341315 CCC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)C[C@H](O)[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51NO4/c1-5-31(36)14-16-32(17-15-31)28(35)11-6-20(2)24-9-10-25-23-8-7-21-18-22(33)19-27(34)30(21,4)26(23)12-13-29(24,25)3/h7,20,22-27,33-34,36H,5-6,8-19H2,1-4H3/t20-,22-,23+,24-,25+,26+,27+,29-,30+/m1/s1 MQTMGKTZLJGFLZ-MKGCCZOYSA-N 629859 US20230340011, Example 156. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629859&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312646 485657524 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341317 C[C@H](CCC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C InChI=1S/C26H43NO3/c1-16(6-11-23(30)27(4)5)20-9-10-21-19-8-7-17-14-18(28)12-13-25(17,2)24(19)22(29)15-26(20,21)3/h7,16,18-22,24,28-29H,6,8-15H2,1-5H3/t16-,18+,19+,20-,21+,22+,24-,25+,26-/m1/s1 IGDJCLLQHVLUAR-ZKFXTWPMSA-N 629860 US20230340011, Example 157. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629860&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312847 485657525 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341319 CCC1(O)CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C InChI=1S/C31H51NO4/c1-5-31(36)14-16-32(17-15-31)27(35)11-6-20(2)24-9-10-25-23-8-7-21-18-22(33)12-13-29(21,3)28(23)26(34)19-30(24,25)4/h7,20,22-26,28,33-34,36H,5-6,8-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,28-,29+,30-/m1/s1 NTADGJLCICPJEW-ZTYLRCHISA-N 629861 US20230340011, Example 158. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629861&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312132 485657526 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341321 C[C@H](CCc1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO/c1-19(6-7-20-5-4-16-29-18-20)24-10-11-25-23-9-8-21-17-22(30)12-14-27(21,2)26(23)13-15-28(24,25)3/h4-5,8,16,18-19,22-26,30H,6-7,9-15,17H2,1-3H3/t19-,22+,23+,24-,25+,26+,27+,28-/m1/s1 DISKPGIFPMUPPT-LYLGZYPGSA-N 629862 US20230340011, Example 159. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629862&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312868 485657527 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341323 C[C@H](CCc1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO/c1-19(4-5-20-12-16-29-17-13-20)24-8-9-25-23-7-6-21-18-22(30)10-14-27(21,2)26(23)11-15-28(24,25)3/h6,12-13,16-17,19,22-26,30H,4-5,7-11,14-15,18H2,1-3H3/t19-,22+,23+,24-,25+,26+,27+,28-/m1/s1 UYMSSZROBUQQCS-LYLGZYPGSA-N 629863 US20230340011, Example 160. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629863&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312552 485657528 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341325 C[C@H](CCc1cccc(F)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H40FNO/c1-18(7-9-20-5-4-6-26(29)30-20)23-11-12-24-22-10-8-19-17-21(31)13-15-27(19,2)25(22)14-16-28(23,24)3/h4-6,8,18,21-25,31H,7,9-17H2,1-3H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 APXAOVVJEWTEEP-JBZGATTQSA-N 629864 US20230340011, Example 161. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629864&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312623 485657529 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341327 C[C@H](CCc1ccc(F)cn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H40FNO/c1-18(4-7-21-8-6-20(29)17-30-21)24-10-11-25-23-9-5-19-16-22(31)12-14-27(19,2)26(23)13-15-28(24,25)3/h5-6,8,17-18,22-26,31H,4,7,9-16H2,1-3H3/t18-,22+,23+,24-,25+,26+,27+,28-/m1/s1 MSMPTGZZFFZENL-UJSHJDKLSA-N 629865 US20230340011, Example 162. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629865&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312159 485657530 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341329 C[C@H](CCc1cc(F)ccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H40FNO/c1-18(4-6-21-17-20(29)12-15-30-21)24-8-9-25-23-7-5-19-16-22(31)10-13-27(19,2)26(23)11-14-28(24,25)3/h5,12,15,17-18,22-26,31H,4,6-11,13-14,16H2,1-3H3/t18-,22+,23+,24-,25+,26+,27+,28-/m1/s1 MDWLIAOYXBXMNC-UJSHJDKLSA-N 629866 US20230340011, Example 163. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629866&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312710 485657531 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341331 C[C@H](CCc1ncccc1F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H40FNO/c1-18(6-11-26-25(29)5-4-16-30-26)22-9-10-23-21-8-7-19-17-20(31)12-14-27(19,2)24(21)13-15-28(22,23)3/h4-5,7,16,18,20-24,31H,6,8-15,17H2,1-3H3/t18-,20+,21+,22-,23+,24+,27+,28-/m1/s1 PEXTYHKAEVEVLU-KVBJCFKZSA-N 629867 US20230340011, Example 164. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629867&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312175 485657532 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341333 C[C@H](CCc1cccc(Cl)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H40ClNO/c1-18(7-9-20-5-4-6-26(29)30-20)23-11-12-24-22-10-8-19-17-21(31)13-15-27(19,2)25(22)14-16-28(23,24)3/h4-6,8,18,21-25,31H,7,9-17H2,1-3H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 DSLUKIMSJXCTOX-JBZGATTQSA-N 629868 US20230340011, Example 165. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629868&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311965 485657533 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341335 C[C@H](CCc1cccc(n1)C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H40F3NO/c1-18(7-9-20-5-4-6-26(33-20)29(30,31)32)23-11-12-24-22-10-8-19-17-21(34)13-15-27(19,2)25(22)14-16-28(23,24)3/h4-6,8,18,21-25,34H,7,9-17H2,1-3H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 YYZFCOYLYXBXHS-JBZGATTQSA-N 629869 US20230340011, Example 166. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629869&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312062 485657534 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341337 CCc1cccc(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 InChI=1S/C30H45NO/c1-5-22-7-6-8-23(31-22)11-9-20(2)26-13-14-27-25-12-10-21-19-24(32)15-17-29(21,3)28(25)16-18-30(26,27)4/h6-8,10,20,24-28,32H,5,9,11-19H2,1-4H3/t20-,24+,25+,26-,27+,28+,29+,30-/m1/s1 ZQELIQXHTQWPJG-LFFMLFRDSA-N 629870 US20230340011, Example 167. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629870&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312765 485657535 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341339 COc1cccc(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 InChI=1S/C29H43NO2/c1-19(8-10-21-6-5-7-27(30-21)32-4)24-12-13-25-23-11-9-20-18-22(31)14-16-28(20,2)26(23)15-17-29(24,25)3/h5-7,9,19,22-26,31H,8,10-18H2,1-4H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 UWSGGNOKEJFKRG-HSIBUNQISA-N 629871 US20230340011, Example 168. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629871&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311906 485657536 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341340 C[C@H](CCc1ccnnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H40N2O/c1-18(4-5-19-12-15-28-29-17-19)23-8-9-24-22-7-6-20-16-21(30)10-13-26(20,2)25(22)11-14-27(23,24)3/h6,12,15,17-18,21-25,30H,4-5,7-11,13-14,16H2,1-3H3/t18-,21+,22+,23-,24+,25+,26+,27-/m1/s1 IYTKURBPSKETDU-NVVJDQLXSA-N 629872 US20230340011, Example 170. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629872&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312790 485657537 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341342 C[C@H](CCc1cncnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H40N2O/c1-18(4-5-19-15-28-17-29-16-19)23-8-9-24-22-7-6-20-14-21(30)10-12-26(20,2)25(22)11-13-27(23,24)3/h6,15-18,21-25,30H,4-5,7-14H2,1-3H3/t18-,21+,22+,23-,24+,25+,26+,27-/m1/s1 QBROHYGUULMCPL-NVVJDQLXSA-N 629873 US20230340011, Example 171. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629873&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311848 485657538 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341344 C[C@H](CCc1nccs1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H39NOS/c1-17(4-9-24-27-14-15-29-24)21-7-8-22-20-6-5-18-16-19(28)10-12-25(18,2)23(20)11-13-26(21,22)3/h5,14-15,17,19-23,28H,4,6-13,16H2,1-3H3/t17-,19+,20+,21-,22+,23+,25+,26-/m1/s1 UACADRBILAHQRV-LXVLQKCJSA-N 629874 US20230340011, Example 172. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629874&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312269 485657539 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341346 C[C@H](CCc1cncs1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H39NOS/c1-17(4-6-20-15-27-16-29-20)22-8-9-23-21-7-5-18-14-19(28)10-12-25(18,2)24(21)11-13-26(22,23)3/h5,15-17,19,21-24,28H,4,6-14H2,1-3H3/t17-,19+,21+,22-,23+,24+,25+,26-/m1/s1 BGDIVPCXAXCQQE-LVALCQIDSA-N 629875 US20230340011, Example 173. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629875&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312088 485657540 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341348 C[C@H](CCc1ncns1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C25H38N2OS/c1-16(4-9-23-26-15-27-29-23)20-7-8-21-19-6-5-17-14-18(28)10-12-24(17,2)22(19)11-13-25(20,21)3/h5,15-16,18-22,28H,4,6-14H2,1-3H3/t16-,18+,19+,20-,21+,22+,24+,25-/m1/s1 CYJDPJOAWCSPNC-OZECAXSSSA-N 629876 US20230340011, Example 174. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629876&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312356 485657541 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341350 C[C@H](CCc1cscn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H39NOS/c1-17(4-6-19-15-29-16-27-19)22-8-9-23-21-7-5-18-14-20(28)10-12-25(18,2)24(21)11-13-26(22,23)3/h5,15-17,20-24,28H,4,6-14H2,1-3H3/t17-,20+,21+,22-,23+,24+,25+,26-/m1/s1 ODKJKQROXQMMRU-ISLLTSAGSA-N 629877 US20230340011, Example 175. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629877&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312424 485657542 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341352 C[C@H](CCc1cnsc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H39NOS/c1-17(4-5-18-15-27-29-16-18)22-8-9-23-21-7-6-19-14-20(28)10-12-25(19,2)24(21)11-13-26(22,23)3/h6,15-17,20-24,28H,4-5,7-14H2,1-3H3/t17-,20+,21+,22-,23+,24+,25+,26-/m1/s1 XMNYYVHOJAJPPT-ISLLTSAGSA-N 629878 US20230340011, Example 176. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629878&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312760 485657543 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341354 C[C@H](CCc1ccc2ccccc2n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H43NO/c1-21(8-11-24-12-9-22-6-4-5-7-30(22)33-24)27-14-15-28-26-13-10-23-20-25(34)16-18-31(23,2)29(26)17-19-32(27,28)3/h4-7,9-10,12,21,25-29,34H,8,11,13-20H2,1-3H3/t21-,25+,26+,27-,28+,29+,31+,32-/m1/s1 MYPPWGZSQKIENB-KNLNLFKVSA-N 629879 US20230340011, Example 178. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629879&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312879 485657544 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341356 C[C@H](COc1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H39NO2/c1-18(17-30-25-6-4-5-15-28-25)22-9-10-23-21-8-7-19-16-20(29)11-13-26(19,2)24(21)12-14-27(22,23)3/h4-7,15,18,20-24,29H,8-14,16-17H2,1-3H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 HYZSXCGUKRBOJP-ZHHJOTBYSA-N 629880 US20230340011, Example 179. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629880&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312934 485657545 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341358 C[C@H](COc1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H39NO2/c1-18(17-30-21-5-4-14-28-16-21)23-8-9-24-22-7-6-19-15-20(29)10-12-26(19,2)25(22)11-13-27(23,24)3/h4-6,14,16,18,20,22-25,29H,7-13,15,17H2,1-3H3/t18-,20+,22+,23-,24+,25+,26+,27-/m1/s1 SUNPNKKHSZWVKK-ROOYLRQDSA-N 629881 US20230340011, Example 180. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629881&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311960 485657546 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341360 C[C@H](COc1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H39NO2/c1-18(17-30-21-10-14-28-15-11-21)23-6-7-24-22-5-4-19-16-20(29)8-12-26(19,2)25(22)9-13-27(23,24)3/h4,10-11,14-15,18,20,22-25,29H,5-9,12-13,16-17H2,1-3H3/t18-,20+,22+,23-,24+,25+,26+,27-/m1/s1 NGGRXCFMOMIIQZ-ROOYLRQDSA-N 629882 US20230340011, Example 181. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629882&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311918 485657547 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341362 C[C@H](COc1ccccc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H40O2/c1-19(18-30-22-7-5-4-6-8-22)24-11-12-25-23-10-9-20-17-21(29)13-15-27(20,2)26(23)14-16-28(24,25)3/h4-9,19,21,23-26,29H,10-18H2,1-3H3/t19-,21+,23+,24-,25+,26+,27+,28-/m1/s1 WXEISZBAWWMMQF-JPVSLSBLSA-N 629883 US20230340011, Example 182. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629883&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312831 485657548 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341364 C[C@H](CCc1ccns1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H39NOS/c1-17(4-6-20-12-15-27-29-20)22-8-9-23-21-7-5-18-16-19(28)10-13-25(18,2)24(21)11-14-26(22,23)3/h5,12,15,17,19,21-24,28H,4,6-11,13-14,16H2,1-3H3/t17-,19+,21+,22-,23+,24+,25+,26-/m1/s1 LBPLXWBCMBORGS-LVALCQIDSA-N 629884 US20230340011, Example 183. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629884&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311920 485657549 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342072 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)c1cn(C)nn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H51N5O3/c1-21(6-11-30(40)38-17-16-37(19-22(38)2)31(41)29-20-36(5)35-34-29)26-9-10-27-25-8-7-23-18-24(39)12-14-32(23,3)28(25)13-15-33(26,27)4/h7,20-22,24-28,39H,6,8-19H2,1-5H3/t21-,22+,24+,25+,26-,27+,28+,32+,33-/m1/s1 IREKXCSFAIRPCU-PACBQIDMSA-N 630287 US20230340011, Example 587. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630287&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312717 485657855 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342074 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)c1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-22(5-10-31(39)37-18-17-36(20-23(37)2)30-13-16-34-21-35-30)27-8-9-28-26-7-6-24-19-25(38)11-14-32(24,3)29(26)12-15-33(27,28)4/h6,13,16,21-23,25-29,38H,5,7-12,14-15,17-20H2,1-4H3/t22-,23+,25+,26+,27-,28+,29+,32+,33-/m1/s1 YBEZJHLYCGDQJY-GBHBUJJPSA-N 630288 US20230340011, Example 588. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630288&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312109 485657856 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342076 CC(C)OC(=O)N1CCN([C@@H](C)C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H54N2O4/c1-21(2)39-31(38)34-17-18-35(23(4)20-34)30(37)12-7-22(3)27-10-11-28-26-9-8-24-19-25(36)13-15-32(24,5)29(26)14-16-33(27,28)6/h8,21-23,25-29,36H,7,9-20H2,1-6H3/t22-,23+,25+,26+,27-,28+,29+,32+,33-/m1/s1 RNUNDRBOUCHOEL-GBHBUJJPSA-N 630289 US20230340011, Example 589. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630289&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312086 485657857 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342078 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H51N3O3/c1-23(5-10-32(40)38-20-19-37(22-24(38)2)33(41)25-13-17-36-18-14-25)29-8-9-30-28-7-6-26-21-27(39)11-15-34(26,3)31(28)12-16-35(29,30)4/h6,13-14,17-18,23-24,27-31,39H,5,7-12,15-16,19-22H2,1-4H3/t23-,24+,27+,28+,29-,30+,31+,34+,35-/m1/s1 NEPQYLKEASEPCG-XGEGFHRISA-N 630290 US20230340011, Example 590. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630290&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312166 485657858 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342080 COC(=O)N1CCC(CC1)C(=O)NC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N2O4/c1-19(18-31-27(34)20-11-15-32(16-12-20)28(35)36-4)24-7-8-25-23-6-5-21-17-22(33)9-13-29(21,2)26(23)10-14-30(24,25)3/h5,19-20,22-26,33H,6-18H2,1-4H3,(H,31,34)/t19-,22+,23+,24-,25+,26+,29+,30-/m1/s1 HCLYIYGXSVCMAK-ZZDZKXLMSA-N 630291 US20230340011, Example 591. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630291&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312598 485657859 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342083 COC(=O)N1CCN(CC1)C(=O)C[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H46N2O4/c1-19(17-26(33)30-13-15-31(16-14-30)27(34)35-4)23-7-8-24-22-6-5-20-18-21(32)9-11-28(20,2)25(22)10-12-29(23,24)3/h5,19,21-25,32H,6-18H2,1-4H3/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 KVMLXGFUWUFWSD-YIZNBMETSA-N 630293 US20230340011, Example 593. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630293&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312398 485657861 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342085 C[C@H](CC(=O)N1CCN(CC1)C(=O)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O3/c1-21(17-29(38)35-13-15-36(16-14-35)30(39)22-19-33-34(4)20-22)26-7-8-27-25-6-5-23-18-24(37)9-11-31(23,2)28(25)10-12-32(26,27)3/h5,19-21,24-28,37H,6-18H2,1-4H3/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 AQWYJZZGDHOUDI-XKQUNUCNSA-N 630294 US20230340011, Example 594. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630294&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312185 485657862 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342087 C[C@H](CC(=O)N1CCN(CC1)c1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H46N4O2/c1-21(18-29(37)35-16-14-34(15-17-35)28-10-13-32-20-33-28)25-6-7-26-24-5-4-22-19-23(36)8-11-30(22,2)27(24)9-12-31(25,26)3/h4,10,13,20-21,23-27,36H,5-9,11-12,14-19H2,1-3H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 BGPPLOKGUSDRSB-MIXBDBMTSA-N 630295 US20230340011, Example 595. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630295&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311972 485657863 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342089 [O-][NH+]=O.C[C@H](COC(=O)N1CCN(CC1)C(=O)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O4.HNO2/c1-21(20-40-30(39)36-15-13-35(14-16-36)29(38)22-18-33-34(4)19-22)26-7-8-27-25-6-5-23-17-24(37)9-11-31(23,2)28(25)10-12-32(26,27)3;2-1-3/h5,18-19,21,24-28,37H,6-17,20H2,1-4H3;1H/t21-,24+,25+,26-,27+,28+,31+,32-;/m1./s1 NQCPHFQCTJUFIQ-IMBRXPTJSA-N 630296 US20230340011, Example 596. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630296&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169490213 485657864 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342091 C[C@H](COC(=O)N1CCN(CC1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H47N3O3/c1-22(21-38-30(37)35-18-16-34(17-19-35)24-10-14-33-15-11-24)27-6-7-28-26-5-4-23-20-25(36)8-12-31(23,2)29(26)9-13-32(27,28)3/h4,10-11,14-15,22,25-29,36H,5-9,12-13,16-21H2,1-3H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 BIGHYKAYZPGDNH-NWKCFVCZSA-N 630297 US20230340011, Example 597. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630297&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312435 485657865 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342093 COC(=O)N1CCN(CC1)C(=O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H44N2O4/c1-18(25(32)29-13-15-30(16-14-29)26(33)34-4)22-7-8-23-21-6-5-19-17-20(31)9-11-27(19,2)24(21)10-12-28(22,23)3/h5,18,20-24,31H,6-17H2,1-4H3/t18-,20-,21-,22+,23-,24-,27-,28+/m0/s1 WAHXUUMZXWQHKL-LVDMELCGSA-N 630298 US20230340011, Example 598. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630298&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312436 485657866 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342095 C[C@@H]([C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(=O)NCc1ccncc1 InChI=1S/C28H40N2O2/c1-18(26(32)30-17-19-10-14-29-15-11-19)23-6-7-24-22-5-4-20-16-21(31)8-12-27(20,2)25(22)9-13-28(23,24)3/h4,10-11,14-15,18,21-25,31H,5-9,12-13,16-17H2,1-3H3,(H,30,32)/t18-,21-,22-,23+,24-,25-,27-,28+/m0/s1 VCDFUPBXTKWTKI-SCIWQTMTSA-N 630299 US20230340011, Example 599. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630299&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312840 485657867 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342097 C[C@@H]([C@H]1CC[C@H]2[C@@H]3CCC4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(=O)Nc1ccncc1 InChI=1S/C27H40N2O2/c1-17(25(31)29-19-10-14-28-15-11-19)22-6-7-23-21-5-4-18-16-20(30)8-12-26(18,2)24(21)9-13-27(22,23)3/h10-11,14-15,17-18,20-24,30H,4-9,12-13,16H2,1-3H3,(H,28,29,31)/t17-,18?,20-,21-,22+,23-,24-,26-,27+/m0/s1 RIYHBOZGVFPXOT-MAFAIHIWSA-N 630300 US20230340011, Example 600. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630300&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311944 485657868 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342099 COc1ccc(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)nc1 InChI=1S/C29H43NO2/c1-19(5-7-21-8-9-23(32-4)18-30-21)25-11-12-26-24-10-6-20-17-22(31)13-15-28(20,2)27(24)14-16-29(25,26)3/h6,8-9,18-19,22,24-27,31H,5,7,10-17H2,1-4H3/t19-,22+,24+,25-,26+,27+,28+,29-/m1/s1 XKHJXONKBHSNJH-LNIDTYFPSA-N 630301 US20230340011, Example 601. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630301&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312579 485657869 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342101 COc1ccnc(CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)c1 InChI=1S/C29H43NO2/c1-19(5-7-21-18-23(32-4)13-16-30-21)25-9-10-26-24-8-6-20-17-22(31)11-14-28(20,2)27(24)12-15-29(25,26)3/h6,13,16,18-19,22,24-27,31H,5,7-12,14-15,17H2,1-4H3/t19-,22+,24+,25-,26+,27+,28+,29-/m1/s1 USHFRBPWRXEGPO-LNIDTYFPSA-N 630302 US20230340011, Example 602. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630302&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312655 485657870 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342103 C[C@H](CCC(=O)N1CCN(CC1)c1cnn(C)c1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N4O2/c1-22(6-11-31(39)37-18-16-36(17-19-37)30-21-34-35(5)23(30)2)27-9-10-28-26-8-7-24-20-25(38)12-14-32(24,3)29(26)13-15-33(27,28)4/h7,21-22,25-29,38H,6,8-20H2,1-5H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 KJHCLECDZYBRIB-VEQXFWRMSA-N 630303 US20230340011, Example 603. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630303&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312495 485657871 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342105 C[C@H](CCC(=O)N1CCN(CC1)c1cn(C)nc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N4O2/c1-22(6-11-31(39)37-18-16-36(17-19-37)30-21-35(5)34-23(30)2)27-9-10-28-26-8-7-24-20-25(38)12-14-32(24,3)29(26)13-15-33(27,28)4/h7,21-22,25-29,38H,6,8-20H2,1-5H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 HXXYUJVIHHZZSC-VEQXFWRMSA-N 630304 US20230340011, Example 604. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630304&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312040 485657872 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342107 C[C@H](CCC(=O)N1CCN(CC1)c1ncnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49N5O2/c1-21(5-10-28(38)35-15-17-36(18-16-35)29-32-20-33-34(29)4)25-8-9-26-24-7-6-22-19-23(37)11-13-30(22,2)27(24)12-14-31(25,26)3/h6,20-21,23-27,37H,5,7-19H2,1-4H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 IZSDNSOGECUVFV-MIXBDBMTSA-N 630305 US20230340011, Example 605. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630305&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312220 485657873 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342109 C[C@H](CCC(=O)N1CCN(CC1)c1nnnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N6O2/c1-20(5-10-27(38)35-15-17-36(18-16-35)28-31-32-33-34(28)4)24-8-9-25-23-7-6-21-19-22(37)11-13-29(21,2)26(23)12-14-30(24,25)3/h6,20,22-26,37H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 BKZAUVDETMVZRQ-RFWRZFGQSA-N 630306 US20230340011, Example 606. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630306&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312734 485657874 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342111 C[C@H](CCC(=O)N1CCN(CC1)c1scnc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N3O2S/c1-21(5-10-29(37)34-15-17-35(18-16-34)30-22(2)33-20-38-30)26-8-9-27-25-7-6-23-19-24(36)11-13-31(23,3)28(25)12-14-32(26,27)4/h6,20-21,24-28,36H,5,7-19H2,1-4H3/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 ZBWGKWVSXFYISC-XKQUNUCNSA-N 630307 US20230340011, Example 607. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630307&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312033 485657875 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342113 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)c1ccnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N4O2/c1-22(6-11-31(39)36-18-19-37(23(2)21-36)30-14-17-34-35(30)5)27-9-10-28-26-8-7-24-20-25(38)12-15-32(24,3)29(26)13-16-33(27,28)4/h7,14,17,22-23,25-29,38H,6,8-13,15-16,18-21H2,1-5H3/t22-,23+,25+,26+,27-,28+,29+,32+,33-/m1/s1 WABGIJULEGGZSY-GBHBUJJPSA-N 630308 US20230340011, Example 608. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630308&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312320 485657876 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342115 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)c1ccnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N4O2/c1-22(6-11-31(39)37-19-18-36(21-23(37)2)30-14-17-34-35(30)5)27-9-10-28-26-8-7-24-20-25(38)12-15-32(24,3)29(26)13-16-33(27,28)4/h7,14,17,22-23,25-29,38H,6,8-13,15-16,18-21H2,1-5H3/t22-,23+,25+,26+,27-,28+,29+,32+,33-/m1/s1 RZGIMMITDNKWCC-GBHBUJJPSA-N 630309 US20230340011, Example 609. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630309&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312523 485657877 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342117 COc1nccnc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-29(39)36-17-19-37(20-18-36)30-31(40-4)35-16-15-34-30)26-8-9-27-25-7-6-23-21-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,15-16,22,24-28,38H,5,7-14,17-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 XCVSAHPJJXXZMS-WKFLPMMISA-N 630310 US20230340011, Example 610. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630310&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311856 485657878 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342119 COc1ccncc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O3/c1-23(5-10-32(39)37-19-17-36(18-20-37)30-22-35-16-13-31(30)40-4)27-8-9-28-26-7-6-24-21-25(38)11-14-33(24,2)29(26)12-15-34(27,28)3/h6,13,16,22-23,25-29,38H,5,7-12,14-15,17-21H2,1-4H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 FDURPDQDEBMJFM-NVYQQUOZSA-N 630311 US20230340011, Example 611. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630311&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312766 485657879 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342121 COc1ncccc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O3/c1-23(7-12-31(39)37-20-18-36(19-21-37)30-6-5-17-35-32(30)40-4)27-10-11-28-26-9-8-24-22-25(38)13-15-33(24,2)29(26)14-16-34(27,28)3/h5-6,8,17,23,25-29,38H,7,9-16,18-22H2,1-4H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 CFFAPFPNMRWVCG-NVYQQUOZSA-N 630312 US20230340011, Example 612. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630312&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312818 485657880 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341366 C[C@H](CCc1ncccc1Cl)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H40ClNO/c1-18(6-11-26-25(29)5-4-16-30-26)22-9-10-23-21-8-7-19-17-20(31)12-14-27(19,2)24(21)13-15-28(22,23)3/h4-5,7,16,18,20-24,31H,6,8-15,17H2,1-3H3/t18-,20+,21+,22-,23+,24+,27+,28-/m1/s1 YNSYKKYXQNNNKQ-KVBJCFKZSA-N 629885 US20230340011, Example 184. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629885&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312430 485657550 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341368 C[C@H](CCc1ncccc1C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H40F3NO/c1-18(6-11-26-25(29(30,31)32)5-4-16-33-26)22-9-10-23-21-8-7-19-17-20(34)12-14-27(19,2)24(21)13-15-28(22,23)3/h4-5,7,16,18,20-24,34H,6,8-15,17H2,1-3H3/t18-,20+,21+,22-,23+,24+,27+,28-/m1/s1 ZGFAMHOPGSLNQT-KVBJCFKZSA-N 629886 US20230340011, Example 185. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629886&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312679 485657551 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341370 COc1cccnc1CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H43NO2/c1-19(7-12-26-27(32-4)6-5-17-30-26)23-10-11-24-22-9-8-20-18-21(31)13-15-28(20,2)25(22)14-16-29(23,24)3/h5-6,8,17,19,21-25,31H,7,9-16,18H2,1-4H3/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 XPLRJSGSDRXZOR-YIZNBMETSA-N 629887 US20230340011, Example 186. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629887&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312423 485657552 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341372 CCc1cccnc1CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H45NO/c1-5-21-7-6-18-31-28(21)13-8-20(2)25-11-12-26-24-10-9-22-19-23(32)14-16-29(22,3)27(24)15-17-30(25,26)4/h6-7,9,18,20,23-27,32H,5,8,10-17,19H2,1-4H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 PMDYUAIUKNIGJN-CMZGQUJUSA-N 629888 US20230340011, Example 187. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629888&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312688 485657553 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341374 C[C@H](CCc1cncnc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H42N2O/c1-18(5-6-20-16-29-17-30-19(20)2)24-9-10-25-23-8-7-21-15-22(31)11-13-27(21,3)26(23)12-14-28(24,25)4/h7,16-18,22-26,31H,5-6,8-15H2,1-4H3/t18-,22+,23+,24-,25+,26+,27+,28-/m1/s1 OYMGBSNJLKHUEN-UJSHJDKLSA-N 629889 US20230340011, Example 188. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629889&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311888 485657554 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341376 C[C@H](CCc1cc(C)ncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H42N2O/c1-18(5-7-21-15-19(2)29-17-30-21)24-9-10-25-23-8-6-20-16-22(31)11-13-27(20,3)26(23)12-14-28(24,25)4/h6,15,17-18,22-26,31H,5,7-14,16H2,1-4H3/t18-,22+,23+,24-,25+,26+,27+,28-/m1/s1 SNEBBLHITUFKML-UJSHJDKLSA-N 629890 US20230340011, Example 189. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629890&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312060 485657555 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341378 C[C@H](CCc1ccnc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H42N2O/c1-18(5-7-21-13-16-29-19(2)30-21)24-9-10-25-23-8-6-20-17-22(31)11-14-27(20,3)26(23)12-15-28(24,25)4/h6,13,16,18,22-26,31H,5,7-12,14-15,17H2,1-4H3/t18-,22+,23+,24-,25+,26+,27+,28-/m1/s1 XUKJHGGJFKQTEH-UJSHJDKLSA-N 629891 US20230340011, Example 190. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629891&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312737 485657556 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341380 C.C[C@H](CCc1nccc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H42N2O.CH4/c1-18(5-10-26-29-16-13-19(2)30-26)23-8-9-24-22-7-6-20-17-21(31)11-14-27(20,3)25(22)12-15-28(23,24)4;/h6,13,16,18,21-25,31H,5,7-12,14-15,17H2,1-4H3;1H4/t18-,21+,22+,23-,24+,25+,27+,28-;/m1./s1 LRYXXVYITCHNRL-ZSPJWJBVSA-N 629892 US20230340011, Example 191. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629892&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169490212 485657557 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341382 C[C@H](CCc1ncc(C)cn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H42N2O/c1-18-16-29-26(30-17-18)10-5-19(2)23-8-9-24-22-7-6-20-15-21(31)11-13-27(20,3)25(22)12-14-28(23,24)4/h6,16-17,19,21-25,31H,5,7-15H2,1-4H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 XRVHPPIRAVVMQP-JDTILAPWSA-N 629893 US20230340011, Example 192. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629893&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312745 485657558 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341384 C[C@H](CCC(=O)N1CCC(O)(CC1)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51NO3/c1-21(4-11-29(35)33-18-16-32(36,17-19-33)22-5-6-22)26-9-10-27-25-8-7-23-20-24(34)12-14-30(23,2)28(25)13-15-31(26,27)3/h7,21-22,24-28,34,36H,4-6,8-20H2,1-3H3/t21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 UJPXVPZVYQWTNV-ANSWHRQLSA-N 629894 US20230340011, Example 193. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629894&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312616 485657559 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341386 C[C@H](CCC(=O)N1CCC(=CC1)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49NO2/c1-21(4-11-30(35)33-18-14-23(15-19-33)22-5-6-22)27-9-10-28-26-8-7-24-20-25(34)12-16-31(24,2)29(26)13-17-32(27,28)3/h7,14,21-22,25-29,34H,4-6,8-13,15-20H2,1-3H3/t21-,25+,26+,27-,28+,29+,31+,32-/m1/s1 OXKQDWPPAHIMFA-KNLNLFKVSA-N 629895 US20230340011, Example 193A Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629895&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312295 485657560 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341388 C[C@H](CCC(=O)N1CCC(O)(CC1)C1CCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H53NO3/c1-22(7-12-30(36)34-19-17-33(37,18-20-34)23-5-4-6-23)27-10-11-28-26-9-8-24-21-25(35)13-15-31(24,2)29(26)14-16-32(27,28)3/h8,22-23,25-29,35,37H,4-7,9-21H2,1-3H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 RJYMOOPMEGOASM-NWKCFVCZSA-N 629896 US20230340011, Example 194. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629896&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312618 485657561 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341390 CCCN(CC)C(=O)C(=O)O[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO4/c1-6-16-29(7-2)25(31)26(32)33-18(3)22-10-11-23-21-9-8-19-17-20(30)12-14-27(19,4)24(21)13-15-28(22,23)5/h8,18,20-24,30H,6-7,9-17H2,1-5H3/t18-,20-,21-,22+,23-,24-,27-,28+/m0/s1 DWCPRJUDNHKHTC-LVDMELCGSA-N 629897 US20230340011, Example 195. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629897&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312561 485657562 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341392 CCCN(CCC)C(=O)C(=O)O[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47NO4/c1-6-16-30(17-7-2)26(32)27(33)34-19(3)23-10-11-24-22-9-8-20-18-21(31)12-14-28(20,4)25(22)13-15-29(23,24)5/h8,19,21-25,31H,6-7,9-18H2,1-5H3/t19-,21-,22-,23+,24-,25-,28-,29+/m0/s1 WPHJMVHLDRMXMZ-YATFVDHGSA-N 629898 US20230340011, Example 196. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629898&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312082 485657563 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341394 CCN(C(C)C)C(=O)C(=O)O[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H45NO4/c1-7-29(17(2)3)25(31)26(32)33-18(4)22-10-11-23-21-9-8-19-16-20(30)12-14-27(19,5)24(21)13-15-28(22,23)6/h8,17-18,20-24,30H,7,9-16H2,1-6H3/t18-,20-,21-,22+,23-,24-,27-,28+/m0/s1 XFQGWLIVIXXPEQ-LVDMELCGSA-N 629899 US20230340011, Example 197. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629899&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312152 485657564 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341396 C[C@H](OC(=O)C(=O)N1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H41NO4/c1-17(32-25(31)24(30)28-14-4-5-15-28)21-8-9-22-20-7-6-18-16-19(29)10-12-26(18,2)23(20)11-13-27(21,22)3/h6,17,19-23,29H,4-5,7-16H2,1-3H3/t17-,19-,20-,21+,22-,23-,26-,27+/m0/s1 QXRWSMJUFZVVMX-GSXUXVAXSA-N 629900 US20230340011, Example 198. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629900&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311974 485657565 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341398 C[C@H](OC(=O)C(=O)N1CCCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H43NO4/c1-18(33-26(32)25(31)29-15-5-4-6-16-29)22-9-10-23-21-8-7-19-17-20(30)11-13-27(19,2)24(21)12-14-28(22,23)3/h7,18,20-24,30H,4-6,8-17H2,1-3H3/t18-,20-,21-,22+,23-,24-,27-,28+/m0/s1 LNWLDMNCWKABRN-LVDMELCGSA-N 629901 US20230340011, Example 199. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629901&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312820 485657566 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341400 CCC1(O)CCN(CC1)C(=O)C(=O)O[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H47NO5/c1-5-30(35)14-16-31(17-15-30)26(33)27(34)36-19(2)23-8-9-24-22-7-6-20-18-21(32)10-12-28(20,3)25(22)11-13-29(23,24)4/h6,19,21-25,32,35H,5,7-18H2,1-4H3/t19-,21-,22-,23+,24-,25-,28-,29+/m0/s1 XOZNOSJYWYFWQA-YATFVDHGSA-N 629902 US20230340011, Example 200. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629902&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312858 485657567 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341402 CC[C@]1(CCCN(C1)C(=O)C(=O)O[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)OC InChI=1S/C31H49NO5/c1-6-31(36-5)14-7-17-32(19-31)27(34)28(35)37-20(2)24-10-11-25-23-9-8-21-18-22(33)12-15-29(21,3)26(23)13-16-30(24,25)4/h8,20,22-26,33H,6-7,9-19H2,1-5H3/t20-,22-,23-,24+,25-,26-,29-,30+,31+/m0/s1 DSHQOFIISJIHSL-CGTRYJCUSA-N 629903 US20230340011, Example 201. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629903&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312389 485657568 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341404 COc1nccc(n1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)37-19-17-36(18-20-37)29-13-16-34-31(35-29)40-4)26-8-9-27-25-7-6-23-21-24(38)11-14-32(23,2)28(25)12-15-33(26,27)3/h6,13,16,22,24-28,38H,5,7-12,14-15,17-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 YJGOUXYVQXLPRP-WKFLPMMISA-N 629904 US20230340011, Example 202.::US20230340011, Example 513. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629904&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312920 485657569 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341406 COc1cc(ncn1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-31(39)37-17-15-36(16-18-37)29-20-30(40-4)35-21-34-29)26-8-9-27-25-7-6-23-19-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,20-22,24-28,38H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 HNZMQAVQKRECOQ-WKFLPMMISA-N 629905 US20230340011, Example 203.::US20230340011, Example 512. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629905&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312918 485657570 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341408 COc1cncnc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)36-15-17-37(18-16-36)31-29(40-4)20-34-21-35-31)26-8-9-27-25-7-6-23-19-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,20-22,24-28,38H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 LWJFQQZIYMDLDR-WKFLPMMISA-N 629906 US20230340011, Example 204.::US20230340011, Example 511. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629906&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312494 485657571 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341410 C[C@H](CCC(=O)N1CCN(CC1)c1ccnc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-22(5-10-31(39)37-19-17-36(18-20-37)30-13-16-34-23(2)35-30)27-8-9-28-26-7-6-24-21-25(38)11-14-32(24,3)29(26)12-15-33(27,28)4/h6,13,16,22,25-29,38H,5,7-12,14-15,17-21H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 GMTRDTRPHPJYOE-VEQXFWRMSA-N 629907 US20230340011, Example 205.::US20230340011, Example 510. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629907&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312572 485657572 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341412 C[C@H](CCC(=O)N1CCN(CC1)c1cc(C)ncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-22(5-10-31(39)37-17-15-36(16-18-37)30-19-23(2)34-21-35-30)27-8-9-28-26-7-6-24-20-25(38)11-13-32(24,3)29(26)12-14-33(27,28)4/h6,19,21-22,25-29,38H,5,7-18,20H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 CFSUSONFVVMLHG-VEQXFWRMSA-N 629908 US20230340011, Example 206.::US20230340011, Example 509. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629908&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312750 485657573 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341414 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H53N3O3/c1-23(6-11-30(38)34-18-20-36(21-19-34)31(39)35-16-4-5-17-35)27-9-10-28-26-8-7-24-22-25(37)12-14-32(24,2)29(26)13-15-33(27,28)3/h7,23,25-29,37H,4-6,8-22H2,1-3H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 XKHYNLJLTFPZKD-ACBDEFBISA-N 629909 US20230340011, Example 207. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629909&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312400 485657574 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342123 COc1cccnc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O3/c1-23(7-12-31(39)36-18-20-37(21-19-36)32-30(40-4)6-5-17-35-32)27-10-11-28-26-9-8-24-22-25(38)13-15-33(24,2)29(26)14-16-34(27,28)3/h5-6,8,17,23,25-29,38H,7,9-16,18-22H2,1-4H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 FJCBNFBEFDLLIN-NVYQQUOZSA-N 630313 US20230340011, Example 613. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630313&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312478 485657881 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342125 COc1ncncc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)37-17-15-36(16-18-37)29-20-34-21-35-31(29)40-4)26-8-9-27-25-7-6-23-19-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,20-22,24-28,38H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 BIKKTZMAXKKOSA-WKFLPMMISA-N 630314 US20230340011, Example 614. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630314&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311873 485657882 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342127 COc1cncnc1N1CCN([C@@H](C)C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O3/c1-22(6-11-31(40)38-17-16-37(20-23(38)2)32-30(41-5)19-35-21-36-32)27-9-10-28-26-8-7-24-18-25(39)12-14-33(24,3)29(26)13-15-34(27,28)4/h7,19,21-23,25-29,39H,6,8-18,20H2,1-5H3/t22-,23+,25+,26+,27-,28+,29+,33+,34-/m1/s1 BKLYABRRQVHXNB-KDUNHSFTSA-N 630315 US20230340011, Example 615.::US20230340011, Example 616. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630315&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312394 485657883 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342129 COc1cncnc1N1CCN([C@@H](C)C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O3/c1-22(6-11-31(40)38-17-16-37(20-23(38)2)32-30(41-5)19-35-21-36-32)27-9-10-28-26-8-7-24-18-25(39)12-14-33(24,3)29(26)13-15-34(27,28)4/h7,19,21-23,25-29,39H,6,8-18,20H2,1-5H3/t22-,23+,25+,26+,27-,28+,29+,33+,34-/m1/s1 BKLYABRRQVHXNB-KDUNHSFTSA-N 630315 US20230340011, Example 615.::US20230340011, Example 616. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630315&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312394 485657883 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342131 COc1ncc(OC)c(n1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O4/c1-22(6-11-30(40)37-16-18-38(19-17-37)31-29(41-4)21-35-32(36-31)42-5)26-9-10-27-25-8-7-23-20-24(39)12-14-33(23,2)28(25)13-15-34(26,27)3/h7,21-22,24-28,39H,6,8-20H2,1-5H3/t22-,24+,25+,26-,27+,28+,33+,34-/m1/s1 OXFIFJRDSHEYDB-CKRNQTFXSA-N 630317 US20230340011, Example 617. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630317&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312792 485657884 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342133 COc1ncnc(N2CCN([C@@H](C)C2)C(=O)CC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)c1OC InChI=1S/C35H54N4O4/c1-22(7-12-30(41)39-18-17-38(20-23(39)2)32-31(42-5)33(43-6)37-21-36-32)27-10-11-28-26-9-8-24-19-25(40)13-15-34(24,3)29(26)14-16-35(27,28)4/h8,21-23,25-29,40H,7,9-20H2,1-6H3/t22-,23+,25+,26+,27-,28+,29+,34+,35-/m1/s1 VZRSPQBZJTUCIK-WSFDCJDQSA-N 630318 US20230340011, Example 618. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630318&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312769 485657885 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342135 C[C@H](CCC(=O)N1CCN(CC1)c1ncncc1C(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H47F3N4O2/c1-21(4-9-29(42)39-14-16-40(17-15-39)30-28(33(34,35)36)19-37-20-38-30)25-7-8-26-24-6-5-22-18-23(41)10-12-31(22,2)27(24)11-13-32(25,26)3/h5,19-21,23-27,41H,4,6-18H2,1-3H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 FVZWYPOQLLDMHL-GTORSBDHSA-N 630319 US20230340011, Example 619. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630319&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312634 485657886 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342137 C[C@H](CCC(=O)N1CCN(CC1)c1ncncc1C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N4O2/c1-23(4-11-32(41)38-16-18-39(19-17-38)33-28(24-5-6-24)21-36-22-37-33)29-9-10-30-27-8-7-25-20-26(40)12-14-34(25,2)31(27)13-15-35(29,30)3/h7,21-24,26-27,29-31,40H,4-6,8-20H2,1-3H3/t23-,26+,27+,29-,30+,31+,34+,35-/m1/s1 DKBYHYZAWJFLDG-KSDBVAEQSA-N 630320 US20230340011, Example 620. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630320&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311861 485657887 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342139 C[C@H](CCC(=O)N1CCN(CC1)c1ncncc1OC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N4O3/c1-23(4-11-32(41)38-16-18-39(19-17-38)33-31(21-36-22-37-33)42-26-6-7-26)28-9-10-29-27-8-5-24-20-25(40)12-14-34(24,2)30(27)13-15-35(28,29)3/h5,21-23,25-30,40H,4,6-20H2,1-3H3/t23-,25+,27+,28-,29+,30+,34+,35-/m1/s1 KTBCRLNTHXWFNY-MIBFSSSPSA-N 630321 US20230340011, Example 621. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630321&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312594 485657888 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342141 COc1cccnc1C1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N2O3/c1-23(7-12-32(39)37-20-15-24(16-21-37)33-31(40-4)6-5-19-36-33)28-10-11-29-27-9-8-25-22-26(38)13-17-34(25,2)30(27)14-18-35(28,29)3/h5-6,8,19,23-24,26-30,38H,7,9-18,20-22H2,1-4H3/t23-,26+,27+,28-,29+,30+,34+,35-/m1/s1 FVOPJBPYQVBYRK-OYNONNFYSA-N 630322 US20230340011, Example 622. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630322&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312279 485657889 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342143 COc1ccccc1C1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H53NO3/c1-24(9-14-34(39)37-21-17-25(18-22-37)28-7-5-6-8-33(28)40-4)30-12-13-31-29-11-10-26-23-27(38)15-19-35(26,2)32(29)16-20-36(30,31)3/h5-8,10,24-25,27,29-32,38H,9,11-23H2,1-4H3/t24-,27+,29+,30-,31+,32+,35+,36-/m1/s1 DZJSOEXANJWVQB-CJPUKWMMSA-N 630323 US20230340011, Example 623. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630323&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312084 485657890 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342145 COc1ccccc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H52N2O3/c1-24(9-14-33(39)37-21-19-36(20-22-37)31-7-5-6-8-32(31)40-4)28-12-13-29-27-11-10-25-23-26(38)15-17-34(25,2)30(27)16-18-35(28,29)3/h5-8,10,24,26-30,38H,9,11-23H2,1-4H3/t24-,26+,27+,28-,29+,30+,34+,35-/m1/s1 OQDJICMYTMXWAW-DSCPWQDPSA-N 630324 US20230340011, Example 624. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630324&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312556 485657891 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342147 COc1cccnc1NC(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H44N2O3/c1-19(7-12-27(34)32-28-26(35-4)6-5-17-31-28)23-10-11-24-22-9-8-20-18-21(33)13-15-29(20,2)25(22)14-16-30(23,24)3/h5-6,8,17,19,21-25,33H,7,9-16,18H2,1-4H3,(H,31,32,34)/t19-,21+,22+,23-,24+,25+,29+,30-/m1/s1 ZNYJBBVOLSTYML-VDLIIDAASA-N 630325 US20230340011, Example 625. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630325&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312797 485657892 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342149 C[C@H](CCC(=O)N1CCOc2cccnc12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H44N2O3/c1-20(6-11-28(35)33-17-18-36-27-5-4-16-32-29(27)33)24-9-10-25-23-8-7-21-19-22(34)12-14-30(21,2)26(23)13-15-31(24,25)3/h4-5,7,16,20,22-26,34H,6,8-15,17-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,30+,31-/m1/s1 RMDCDVHSPZMPHK-HCJGDWAISA-N 630326 US20230340011, Example 626. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630326&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311955 485657893 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342151 COc1ccc2ccnc(N3CCN(CC3)C(=O)CC[C@@H](C)[C@H]3CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC[C@]34C)c2c1 InChI=1S/C38H53N3O3/c1-25(32-10-11-33-30-9-7-27-23-28(42)13-16-37(27,2)34(30)14-17-38(32,33)3)5-12-35(43)40-19-21-41(22-20-40)36-31-24-29(44-4)8-6-26(31)15-18-39-36/h6-8,15,18,24-25,28,30,32-34,42H,5,9-14,16-17,19-23H2,1-4H3/t25-,28+,30+,32-,33+,34+,37+,38-/m1/s1 APDFIIRGANTBAT-GGOOHGBKSA-N 630327 US20230340011, Example 627. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630327&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312406 485657894 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342153 C[C@H](CCC(=O)N1CCN(CC1)c1nccc2ccncc12)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H50N4O2/c1-24(4-9-33(42)39-18-20-40(21-19-39)34-29-23-37-16-12-25(29)13-17-38-34)30-7-8-31-28-6-5-26-22-27(41)10-14-35(26,2)32(28)11-15-36(30,31)3/h5,12-13,16-17,23-24,27-28,30-32,41H,4,6-11,14-15,18-22H2,1-3H3/t24-,27+,28+,30-,31+,32+,35+,36-/m1/s1 AMXQJFNAENIISO-QHYZMFGCSA-N 630328 US20230340011, Example 628. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630328&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312376 485657895 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342155 COc1nnccc1N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)37-19-17-36(18-20-37)29-13-16-34-35-31(29)40-4)26-8-9-27-25-7-6-23-21-24(38)11-14-32(23,2)28(25)12-15-33(26,27)3/h6,13,16,22,24-28,38H,5,7-12,14-15,17-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 WWRMNPLQJPPPJD-WKFLPMMISA-N 630329 US20230340011, Example 629. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630329&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312822 485657896 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342157 C[C@H](CCC(=O)N1CCN(CC1)c1ncncc1O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O3/c1-21(4-9-29(39)35-14-16-36(17-15-35)30-28(38)19-33-20-34-30)25-7-8-26-24-6-5-22-18-23(37)10-12-31(22,2)27(24)11-13-32(25,26)3/h5,19-21,23-27,37-38H,4,6-18H2,1-3H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 IGONUOLUNTYMPA-GTORSBDHSA-N 630330 US20230340011, Example 630. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630330&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312437 485657897 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342159 C[C@H](CCC(=O)N1CCN(CC1)c1cc(O)ncn1)[C@H]1CC[C@H]2C3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O3/c1-21(4-9-30(39)36-16-14-35(15-17-36)28-19-29(38)34-20-33-28)25-7-8-26-24-6-5-22-18-23(37)10-12-31(22,2)27(24)11-13-32(25,26)3/h5,19-21,23-27,37H,4,6-18H2,1-3H3,(H,33,34,38)/t21-,23+,24?,25-,26+,27+,31+,32-/m1/s1 ZICXQWSAKQVAEE-KUEVHPAQSA-N 630331 US20230340011, Example 631. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630331&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311973 485657898 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342161 C[C@H](CCC(=O)N1CCN(CC1)c1ncncc1N)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N5O2/c1-21(4-9-29(39)36-14-16-37(17-15-36)30-28(33)19-34-20-35-30)25-7-8-26-24-6-5-22-18-23(38)10-12-31(22,2)27(24)11-13-32(25,26)3/h5,19-21,23-27,38H,4,6-18,33H2,1-3H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 WKTKMCYWOYDSDR-GTORSBDHSA-N 630332 US20230340011, Example 632. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630332&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312480 485657899 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342163 C[C@H](CCC(=O)N1CCN(CC1)c1cc(N)ncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N5O2/c1-21(4-9-30(39)37-16-14-36(15-17-37)29-19-28(33)34-20-35-29)25-7-8-26-24-6-5-22-18-23(38)10-12-31(22,2)27(24)11-13-32(25,26)3/h5,19-21,23-27,38H,4,6-18H2,1-3H3,(H2,33,34,35)/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 XRADRFAVYIRMTR-GTORSBDHSA-N 630333 US20230340011, Example 633. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630333&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312468 485657900 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342165 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)c1nnc(C)o1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N4O3/c1-20(6-11-29(38)35-16-17-36(21(2)19-35)30-34-33-22(3)39-30)26-9-10-27-25-8-7-23-18-24(37)12-14-31(23,4)28(25)13-15-32(26,27)5/h7,20-21,24-28,37H,6,8-19H2,1-5H3/t20-,21+,24+,25+,26-,27+,28+,31+,32-/m1/s1 LHTLFOPAEKVBLC-IOMCRCLZSA-N 630334 US20230340011, Example 634. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630334&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312198 485657901 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342167 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)c1nnc(C)o1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N4O3/c1-20(6-11-29(38)36-17-16-35(19-21(36)2)30-34-33-22(3)39-30)26-9-10-27-25-8-7-23-18-24(37)12-14-31(23,4)28(25)13-15-32(26,27)5/h7,20-21,24-28,37H,6,8-19H2,1-5H3/t20-,21+,24+,25+,26-,27+,28+,31+,32-/m1/s1 LZTZDCXQQXTAMY-IOMCRCLZSA-N 630335 US20230340011, Example 635. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630335&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312339 485657902 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342169 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)N(C)CC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H57N3O3/c1-23(6-13-32(40)37-18-19-38(24(2)21-37)33(41)36(5)22-25-7-8-25)29-11-12-30-28-10-9-26-20-27(39)14-16-34(26,3)31(28)15-17-35(29,30)4/h9,23-25,27-31,39H,6-8,10-22H2,1-5H3/t23-,24+,27+,28+,29-,30+,31+,34+,35-/m1/s1 LZJVIERZYMJGMU-XGEGFHRISA-N 630336 US20230340011, Example 636. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630336&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312695 485657903 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342171 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)N(C)CC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H57N3O3/c1-23(6-13-32(40)38-19-18-37(21-24(38)2)33(41)36(5)22-25-7-8-25)29-11-12-30-28-10-9-26-20-27(39)14-16-34(26,3)31(28)15-17-35(29,30)4/h9,23-25,27-31,39H,6-8,10-22H2,1-5H3/t23-,24+,27+,28+,29-,30+,31+,34+,35-/m1/s1 GUYPPRHBQGBUKX-XGEGFHRISA-N 630337 US20230340011, Example 637. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630337&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312834 485657904 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341416 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51N3O3/c1-22(5-10-29(37)33-17-19-35(20-18-33)30(38)34-15-4-16-34)26-8-9-27-25-7-6-23-21-24(36)11-13-31(23,2)28(25)12-14-32(26,27)3/h6,22,24-28,36H,4-5,7-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 JPNCRCYDMGWJKV-XJGPRUKRSA-N 629910 US20230340011, Example 208. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629910&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312736 485657575 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341418 COCCN(C)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55N3O4/c1-23(6-11-30(38)35-16-18-36(19-17-35)31(39)34(4)20-21-40-5)27-9-10-28-26-8-7-24-22-25(37)12-14-32(24,2)29(26)13-15-33(27,28)3/h7,23,25-29,37H,6,8-22H2,1-5H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 BGNWSYUVHZOMKR-ACBDEFBISA-N 629911 US20230340011, Example 209.::US20230340011, Example 502. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629911&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312837 485657576 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341420 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N(C)CC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H55N3O3/c1-23(5-12-31(39)36-17-19-37(20-18-36)32(40)35(4)22-24-6-7-24)28-10-11-29-27-9-8-25-21-26(38)13-15-33(25,2)30(27)14-16-34(28,29)3/h8,23-24,26-30,38H,5-7,9-22H2,1-4H3/t23-,26+,27+,28-,29+,30+,33+,34-/m1/s1 MEGAUYUWEKKTDG-WACGHZNISA-N 629912 US20230340011, Example 210.::US20230340011, Example 501. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629912&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312566 485657577 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341422 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N(C)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H53N3O3/c1-22(5-12-30(38)35-17-19-36(20-18-35)31(39)34(4)24-7-8-24)27-10-11-28-26-9-6-23-21-25(37)13-15-32(23,2)29(26)14-16-33(27,28)3/h6,22,24-29,37H,5,7-21H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 FIVIYYCJLJLKHY-VEQXFWRMSA-N 629913 US20230340011, Example 211.::US20230340011, Example 500. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629913&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312288 485657578 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341424 CCN(CC)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55N3O3/c1-6-34(7-2)31(39)36-20-18-35(19-21-36)30(38)13-8-23(3)27-11-12-28-26-10-9-24-22-25(37)14-16-32(24,4)29(26)15-17-33(27,28)5/h9,23,25-29,37H,6-8,10-22H2,1-5H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 HPMPNVICONPUIN-ACBDEFBISA-N 629914 US20230340011, Example 212.::US20230340011, Example 499. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629914&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312045 485657579 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341426 CCN(C)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H53N3O3/c1-6-33(5)30(38)35-19-17-34(18-20-35)29(37)12-7-22(2)26-10-11-27-25-9-8-23-21-24(36)13-15-31(23,3)28(25)14-16-32(26,27)4/h8,22,24-28,36H,6-7,9-21H2,1-5H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 HVTIQXNYTVKWHT-XJGPRUKRSA-N 629915 US20230340011, Example 213.::US20230340011, Example 498. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629915&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312363 485657580 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341428 C[C@H](CCC(=O)N1CCN(CC1)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N4O2/c1-22(5-10-30(38)36-17-15-35(16-18-36)24-20-33-34(4)21-24)27-8-9-28-26-7-6-23-19-25(37)11-13-31(23,2)29(26)12-14-32(27,28)3/h6,20-22,25-29,37H,5,7-19H2,1-4H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 WUHFAJFYONGXPH-NWKCFVCZSA-N 629916 US20230340011, Example 214.::US20230340011, Example 496. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629916&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312126 485657581 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341431 C[C@H](CCC(=O)N1CC[C@@H](C1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H47N3O3/c1-21(4-9-30(37)35-17-13-24(19-35)38-29-12-16-33-20-34-29)26-7-8-27-25-6-5-22-18-23(36)10-14-31(22,2)28(25)11-15-32(26,27)3/h5,12,16,20-21,23-28,36H,4,6-11,13-15,17-19H2,1-3H3/t21-,23+,24+,25+,26-,27+,28+,31+,32-/m1/s1 BCMWWLFUPGUEKZ-FTYDJCRESA-N 629918 US20230340011, Example 216.::US20230340011, Example 493. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629918&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312684 485657583 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341433 C[C@H](CCC(=O)N1CCC[C@H](C1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(6-11-31(38)36-18-4-5-25(20-36)39-30-14-17-34-21-35-30)27-9-10-28-26-8-7-23-19-24(37)12-15-32(23,2)29(26)13-16-33(27,28)3/h7,14,17,21-22,24-29,37H,4-6,8-13,15-16,18-20H2,1-3H3/t22-,24+,25-,26+,27-,28+,29+,32+,33-/m1/s1 IKXWNSKSLJRNQO-GBHVZMROSA-N 629919 US20230340011, Example 217. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629919&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312524 485657584 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341435 C[C@H](CCC(=O)N1CCC[C@@H](C1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(6-11-31(38)36-18-4-5-25(20-36)39-30-14-17-34-21-35-30)27-9-10-28-26-8-7-23-19-24(37)12-15-32(23,2)29(26)13-16-33(27,28)3/h7,14,17,21-22,24-29,37H,4-6,8-13,15-16,18-20H2,1-3H3/t22-,24+,25+,26+,27-,28+,29+,32+,33-/m1/s1 IKXWNSKSLJRNQO-XFRFFNMESA-N 629920 US20230340011, Example 218.::US20230340011, Example 491. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629920&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312849 485657585 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341437 C[C@H](CCC(=O)N1CCC(CC1)Oc1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O3/c1-23(6-11-32(38)36-19-14-26(15-20-36)39-27-5-4-18-35-22-27)29-9-10-30-28-8-7-24-21-25(37)12-16-33(24,2)31(28)13-17-34(29,30)3/h4-5,7,18,22-23,25-26,28-31,37H,6,8-17,19-21H2,1-3H3/t23-,25+,28+,29-,30+,31+,33+,34-/m1/s1 JHSOYPWRPHDAAP-HJIUKPPKSA-N 629921 US20230340011, Example 219.::US20230340011, Example 490. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629921&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312816 485657586 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341439 C[C@H](CCC(=O)N1CCC(CC1)Oc1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(4-9-31(38)36-18-12-25(13-19-36)39-30-21-34-16-17-35-30)27-7-8-28-26-6-5-23-20-24(37)10-14-32(23,2)29(26)11-15-33(27,28)3/h5,16-17,21-22,24-29,37H,4,6-15,18-20H2,1-3H3/t22-,24+,26+,27-,28+,29+,32+,33-/m1/s1 KXSGPQDVIBVOHS-LRVBENBSSA-N 629922 US20230340011, Example 220.::US20230340011, Example 489. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629922&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312261 485657587 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341441 C[C@H](CCC(=O)N1CCC(CC1)Oc1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(4-9-31(38)36-18-13-25(14-19-36)39-30-12-17-34-21-35-30)27-7-8-28-26-6-5-23-20-24(37)10-15-32(23,2)29(26)11-16-33(27,28)3/h5,12,17,21-22,24-29,37H,4,6-11,13-16,18-20H2,1-3H3/t22-,24+,26+,27-,28+,29+,32+,33-/m1/s1 LWYPURHDORNXGY-LRVBENBSSA-N 629923 US20230340011, Example 221.::US20230340011, Example 488. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629923&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312148 485657588 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341443 C[C@H](CCC(=O)N1CCN(CC1)c1cncnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(4-9-30(38)36-16-14-35(15-17-36)24-19-33-21-34-20-24)27-7-8-28-26-6-5-23-18-25(37)10-12-31(23,2)29(26)11-13-32(27,28)3/h5,19-22,25-29,37H,4,6-18H2,1-3H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 KSXZNNYPOJLTTN-NWKCFVCZSA-N 629924 US20230340011, Example 222.::US20230340011, Example 486. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629924&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312041 485657589 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341445 C[C@H](CCC(=O)N1CCN(Cc2cnn(C)c2)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N4O2/c1-23(5-10-31(39)37-17-15-36(16-18-37)22-24-20-34-35(4)21-24)28-8-9-29-27-7-6-25-19-26(38)11-13-32(25,2)30(27)12-14-33(28,29)3/h6,20-21,23,26-30,38H,5,7-19,22H2,1-4H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 CDOZILNPFAZLRV-ZWWVIQJBSA-N 629925 US20230340011, Example 223.::US20230340011, Example 485. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629925&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312892 485657590 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341447 C[C@H](CCC(=O)N1CCN(Cc2cncnc2)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O2/c1-23(4-9-31(39)37-16-14-36(15-17-37)21-24-19-34-22-35-20-24)28-7-8-29-27-6-5-25-18-26(38)10-12-32(25,2)30(27)11-13-33(28,29)3/h5,19-20,22-23,26-30,38H,4,6-18,21H2,1-3H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 FTCDWVMHXIFDOO-ZWWVIQJBSA-N 629926 US20230340011, Example 224.::US20230340011, Example 484. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629926&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312218 485657591 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341449 C[C@H](CCC(=O)N1CCN(CC1)c1nnc(C)s1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N4O2S/c1-20(5-10-28(37)34-15-17-35(18-16-34)29-33-32-21(2)38-29)25-8-9-26-24-7-6-22-19-23(36)11-13-30(22,3)27(24)12-14-31(25,26)4/h6,20,23-27,36H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,30+,31-/m1/s1 LLJXRHHEXGCVNW-NBDGSGAJSA-N 629927 US20230340011, Example 225.::US20230340011, Example 483. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629927&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312664 485657592 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341451 C[C@H](CCC(=O)N1CCN(CC1)c1ccnn1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N4O2/c1-22(5-10-30(38)36-19-17-35(18-20-36)29-13-16-33-34(29)4)26-8-9-27-25-7-6-23-21-24(37)11-14-31(23,2)28(25)12-15-32(26,27)3/h6,13,16,22,24-28,37H,5,7-12,14-15,17-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 BQGAVEMLTLEGMS-XJGPRUKRSA-N 629928 US20230340011, Example 226.::US20230340011, Example 480. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629928&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312321 485657593 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341453 C[C@H](CCC(=O)N1CCC(CC1)C(C)NC(=O)C(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H58N2O4/c1-22(7-12-31(39)37-19-15-24(16-20-37)23(2)36-32(40)33(3,4)41)28-10-11-29-27-9-8-25-21-26(38)13-17-34(25,5)30(27)14-18-35(28,29)6/h8,22-24,26-30,38,41H,7,9-21H2,1-6H3,(H,36,40)/t22-,23?,26+,27+,28-,29+,30+,34+,35-/m1/s1 XAXNJNOMMYEPMI-HNABATGWSA-N 629929 US20230340011, Example 227.::US20230340011, Example 478. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629929&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312396 485657594 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341455 C[C@H](CCC(=O)N1CCC(CNC(=O)OC(C)(C)C)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H58N2O4/c1-23(7-12-31(39)37-19-15-24(16-20-37)22-36-32(40)41-33(2,3)4)28-10-11-29-27-9-8-25-21-26(38)13-17-34(25,5)30(27)14-18-35(28,29)6/h8,23-24,26-30,38H,7,9-22H2,1-6H3,(H,36,40)/t23-,26+,27+,28-,29+,30+,34+,35-/m1/s1 ISVNNKOFCPDLJE-OYNONNFYSA-N 629930 US20230340011, Example 228.::US20230340011, Example 477. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629930&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312160 485657595 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341457 C[C@H](CCC(=O)N1CCC(CC1)C(C)NS(C)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H54N2O4S/c1-21(6-11-30(36)34-18-14-23(15-19-34)22(2)33-39(5,37)38)27-9-10-28-26-8-7-24-20-25(35)12-16-31(24,3)29(26)13-17-32(27,28)4/h7,21-23,25-29,33,35H,6,8-20H2,1-5H3/t21-,22?,25+,26+,27-,28+,29+,31+,32-/m1/s1 FTMWXGJEOQCRSI-TWKOBVMPSA-N 629931 US20230340011, Example 229.::US20230340011, Example 475. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629931&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312432 485657596 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341459 C[C@H](CCC(=O)N1CCC(CN(C)S(C)(=O)=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H54N2O4S/c1-22(6-11-30(36)34-18-14-23(15-19-34)21-33(4)39(5,37)38)27-9-10-28-26-8-7-24-20-25(35)12-16-31(24,2)29(26)13-17-32(27,28)3/h7,22-23,25-29,35H,6,8-21H2,1-5H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 MVAUARKOZFQLRC-NWKCFVCZSA-N 629932 US20230340011, Example 230.::US20230340011, Example 474. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629932&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312280 485657597 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341461 C[C@H](CCC(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H49F3N2O4S/c1-20(4-9-28(38)36-16-12-21(13-17-36)19-35-41(39,40)31(32,33)34)25-7-8-26-24-6-5-22-18-23(37)10-14-29(22,2)27(24)11-15-30(25,26)3/h5,20-21,23-27,35,37H,4,6-19H2,1-3H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 WPEDDRBYKBFFOQ-CMZGQUJUSA-N 629933 US20230340011, Example 231.::US20230340011, Example 473. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629933&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312671 485657598 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341463 C[C@H](CCC(=O)N1CCC(CNS(C)(=O)=O)CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O4S/c1-21(5-10-29(35)33-17-13-22(14-18-33)20-32-38(4,36)37)26-8-9-27-25-7-6-23-19-24(34)11-15-30(23,2)28(25)12-16-31(26,27)3/h6,21-22,24-28,32,34H,5,7-20H2,1-4H3/t21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 DACBBFAVSCNZII-ANSWHRQLSA-N 629934 US20230340011, Example 232.::US20230340011, Example 472. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629934&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312545 485657599 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342173 C[C@H](CCc1ncccc1C#N)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H40N2O/c1-19(6-11-27-20(18-30)5-4-16-31-27)24-9-10-25-23-8-7-21-17-22(32)12-14-28(21,2)26(23)13-15-29(24,25)3/h4-5,7,16,19,22-26,32H,6,8-15,17H2,1-3H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 WUJFTMBEQRXIKG-HSIBUNQISA-N 630338 US20230340011, Example 638. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630338&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311897 485657905 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342175 C[C@H](CCC(=O)N(C)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H44N2O2/c1-20(5-10-28(34)32(4)22-13-17-31-18-14-22)25-8-9-26-24-7-6-21-19-23(33)11-15-29(21,2)27(24)12-16-30(25,26)3/h6,13-14,17-18,20,23-27,33H,5,7-12,15-16,19H2,1-4H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 PMHCNNMWFKSDSM-CMZGQUJUSA-N 630339 US20230340011, Example 639. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630339&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312211 485657906 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342177 C[C@H](CCC(=O)N1CCN(CC1)c1cccnc1O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O3/c1-22(6-11-30(38)36-19-17-35(18-20-36)29-5-4-16-34-31(29)39)26-9-10-27-25-8-7-23-21-24(37)12-14-32(23,2)28(25)13-15-33(26,27)3/h4-5,7,16,22,24-28,37H,6,8-15,17-21H2,1-3H3,(H,34,39)/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 ZFNPDEPMTDWKRE-WKFLPMMISA-N 630340 US20230340011, Example 640. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630340&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312560 485657907 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342179 C[C@H](CCC(=O)N[C@H]1CC[C@H](CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H54N2O3/c1-21(6-15-30(37)34-24-10-7-22(8-11-24)31(38)35(4)5)27-13-14-28-26-12-9-23-20-25(36)16-18-32(23,2)29(26)17-19-33(27,28)3/h9,21-22,24-29,36H,6-8,10-20H2,1-5H3,(H,34,37)/t21-,22-,24+,25+,26+,27-,28+,29+,32+,33-/m1/s1 ODYRPCKVVVEPIL-DLSKVJNVSA-N 630341 US20230340011, Example 641. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630341&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312584 485657908 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342181 C[C@H](CCC(=O)N(C)C1CCN(CC1)C(=O)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H54N2O3/c1-22(5-12-31(38)35(4)25-15-19-36(20-16-25)32(39)23-6-7-23)28-10-11-29-27-9-8-24-21-26(37)13-17-33(24,2)30(27)14-18-34(28,29)3/h8,22-23,25-30,37H,5-7,9-21H2,1-4H3/t22-,26+,27+,28-,29+,30+,33+,34-/m1/s1 SAYZNKGBTYXQOB-BTSBOXAHSA-N 630342 US20230340011, Example 642. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630342&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312355 485657909 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342183 COC(=O)N1CCC(CC1)N(C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O4/c1-21(6-11-29(36)33(4)23-14-18-34(19-15-23)30(37)38-5)26-9-10-27-25-8-7-22-20-24(35)12-16-31(22,2)28(25)13-17-32(26,27)3/h7,21,23-28,35H,6,8-20H2,1-5H3/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 FXNHWGQPCIRLSL-XKQUNUCNSA-N 630343 US20230340011, Example 643. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630343&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312727 485657910 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342185 C[C@H](CCC(=O)N(C)C1CCN(CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H55N3O3/c1-22(7-12-30(38)35(6)24-15-19-36(20-16-24)31(39)34(4)5)27-10-11-28-26-9-8-23-21-25(37)13-17-32(23,2)29(26)14-18-33(27,28)3/h8,22,24-29,37H,7,9-21H2,1-6H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 ASERCKFKPSAEJL-VEQXFWRMSA-N 630344 US20230340011, Example 644. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630344&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312131 485657911 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342187 C[C@H](CCC(=O)N(C)C1CCN(CC1)C(=O)N1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C35H57N3O3/c1-24(7-12-32(40)36(4)26-15-21-38(22-16-26)33(41)37-19-5-6-20-37)29-10-11-30-28-9-8-25-23-27(39)13-17-34(25,2)31(28)14-18-35(29,30)3/h8,24,26-31,39H,5-7,9-23H2,1-4H3/t24-,27+,28+,29-,30+,31+,34+,35-/m1/s1 SMBBUDXVFMUVAO-XRKXWTTISA-N 630345 US20230340011, Example 645. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630345&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312455 485657912 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342189 COc1cc(ncn1)N1CCN(C[C@@H]1C)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O3/c1-22(6-11-32(40)37-16-17-38(23(2)20-37)30-19-31(41-5)36-21-35-30)27-9-10-28-26-8-7-24-18-25(39)12-14-33(24,3)29(26)13-15-34(27,28)4/h7,19,21-23,25-29,39H,6,8-18,20H2,1-5H3/t22-,23+,25+,26+,27-,28+,29+,33+,34-/m1/s1 VMAHZLQJUNEFKP-KDUNHSFTSA-N 630346 US20230340011, Example 646. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630346&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312905 485657913 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342191 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)c1ccnc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O2/c1-22(6-11-32(40)37-18-19-38(23(2)21-37)31-14-17-35-24(3)36-31)28-9-10-29-27-8-7-25-20-26(39)12-15-33(25,4)30(27)13-16-34(28,29)5/h7,14,17,22-23,26-30,39H,6,8-13,15-16,18-21H2,1-5H3/t22-,23+,26+,27+,28-,29+,30+,33+,34-/m1/s1 UNJVYLMEFLRTGU-RCZZVTCRSA-N 630347 US20230340011, Example 647. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630347&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312431 485657914 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342193 COc1cc(ncn1)N1CCN([C@@H](C)C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O3/c1-22(6-11-32(40)38-17-16-37(20-23(38)2)30-19-31(41-5)36-21-35-30)27-9-10-28-26-8-7-24-18-25(39)12-14-33(24,3)29(26)13-15-34(27,28)4/h7,19,21-23,25-29,39H,6,8-18,20H2,1-5H3/t22-,23+,25+,26+,27-,28+,29+,33+,34-/m1/s1 RDYUARWTSKVMEU-KDUNHSFTSA-N 630348 US20230340011, Example 648. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630348&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312861 485657915 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342195 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)c1ccnc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H52N4O2/c1-22(6-11-32(40)38-19-18-37(21-23(38)2)31-14-17-35-24(3)36-31)28-9-10-29-27-8-7-25-20-26(39)12-15-33(25,4)30(27)13-16-34(28,29)5/h7,14,17,22-23,26-30,39H,6,8-13,15-16,18-21H2,1-5H3/t22-,23+,26+,27+,28-,29+,30+,33+,34-/m1/s1 MRBNWYHXSYXMRL-RCZZVTCRSA-N 630349 US20230340011, Example 649. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630349&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312735 485657916 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342197 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N2O3/c1-21(5-12-30(37)34-17-18-35(22(2)20-34)31(38)23-6-7-23)27-10-11-28-26-9-8-24-19-25(36)13-15-32(24,3)29(26)14-16-33(27,28)4/h8,21-23,25-29,36H,5-7,9-20H2,1-4H3/t21-,22+,25+,26+,27-,28+,29+,32+,33-/m1/s1 WWJISRPTVJXFDN-JDZCMLHVSA-N 630350 US20230340011, Example 650. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630350&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311844 485657917 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342199 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N2O3/c1-21(5-12-30(37)35-18-17-34(20-22(35)2)31(38)23-6-7-23)27-10-11-28-26-9-8-24-19-25(36)13-15-32(24,3)29(26)14-16-33(27,28)4/h8,21-23,25-29,36H,5-7,9-20H2,1-4H3/t21-,22+,25+,26+,27-,28+,29+,32+,33-/m1/s1 PSTSPOQHYZEFAG-JDZCMLHVSA-N 630351 US20230340011, Example 651. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630351&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312235 485657918 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342201 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)C(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H54N2O4/c1-21(7-12-29(37)34-17-18-35(22(2)20-34)30(38)31(3,4)39)26-10-11-27-25-9-8-23-19-24(36)13-15-32(23,5)28(25)14-16-33(26,27)6/h8,21-22,24-28,36,39H,7,9-20H2,1-6H3/t21-,22+,24+,25+,26-,27+,28+,32+,33-/m1/s1 LNQLCKCQRAEXLW-PACBQIDMSA-N 630352 US20230340011, Example 652. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630352&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312210 485657919 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342203 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)C(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H54N2O4/c1-21(7-12-29(37)35-18-17-34(20-22(35)2)30(38)31(3,4)39)26-10-11-27-25-9-8-23-19-24(36)13-15-32(23,5)28(25)14-16-33(26,27)6/h8,21-22,24-28,36,39H,7,9-20H2,1-6H3/t21-,22+,24+,25+,26-,27+,28+,32+,33-/m1/s1 SYSIZDHRDUDODR-PACBQIDMSA-N 630353 US20230340011, Example 653. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630353&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312549 485657920 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342205 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(=O)N1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H55N3O3/c1-23(7-12-31(39)36-19-20-37(24(2)22-36)32(40)35-17-5-6-18-35)28-10-11-29-27-9-8-25-21-26(38)13-15-33(25,3)30(27)14-16-34(28,29)4/h8,23-24,26-30,38H,5-7,9-22H2,1-4H3/t23-,24+,26+,27+,28-,29+,30+,33+,34-/m1/s1 SVHZGQRYHCIIQU-ZLDPOVOCSA-N 630354 US20230340011, Example 654. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630354&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312575 485657921 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342207 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(=O)N1CCCC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H55N3O3/c1-23(7-12-31(39)37-20-19-36(22-24(37)2)32(40)35-17-5-6-18-35)28-10-11-29-27-9-8-25-21-26(38)13-15-33(25,3)30(27)14-16-34(28,29)4/h8,23-24,26-30,38H,5-7,9-22H2,1-4H3/t23-,24+,26+,27+,28-,29+,30+,33+,34-/m1/s1 RUJQPYXLVGKYGY-ZLDPOVOCSA-N 630355 US20230340011, Example 655. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630355&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311954 485657922 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342209 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H52N4O2/c1-22(6-11-31(39)36-16-17-37(23(2)20-36)25-19-34-35(5)21-25)28-9-10-29-27-8-7-24-18-26(38)12-14-32(24,3)30(27)13-15-33(28,29)4/h7,19,21-23,26-30,38H,6,8-18,20H2,1-5H3/t22-,23+,26+,27+,28-,29+,30+,32+,33-/m1/s1 JNUMTHQQQWSIKI-LJQNTLLASA-N 630356 US20230340011, Example 656. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630356&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312388 485657923 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342211 COc1ccnc(c1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O3/c1-23(5-10-32(39)37-19-17-36(18-20-37)31-22-26(40-4)13-16-35-31)28-8-9-29-27-7-6-24-21-25(38)11-14-33(24,2)30(27)12-15-34(28,29)3/h6,13,16,22-23,25,27-30,38H,5,7-12,14-15,17-21H2,1-4H3/t23-,25+,27+,28-,29+,30+,33+,34-/m1/s1 DDXFEIQBOYLNEW-MASUEDHOSA-N 630357 US20230340011, Example 657. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630357&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312670 485657924 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342213 C[C@H](CCC(=O)N1CCN(CC1)c1cc(C)ccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O2/c1-23-13-16-35-31(21-23)36-17-19-37(20-18-36)32(39)10-5-24(2)28-8-9-29-27-7-6-25-22-26(38)11-14-33(25,3)30(27)12-15-34(28,29)4/h6,13,16,21,24,26-30,38H,5,7-12,14-15,17-20,22H2,1-4H3/t24-,26+,27+,28-,29+,30+,33+,34-/m1/s1 GPXAVEFGWDMIJA-NPIGIBJLSA-N 630358 US20230340011, Example 658. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630358&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312118 485657925 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342215 COc1cccc(n1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O3/c1-23(8-13-32(39)37-20-18-36(19-21-37)30-6-5-7-31(35-30)40-4)27-11-12-28-26-10-9-24-22-25(38)14-16-33(24,2)29(26)15-17-34(27,28)3/h5-7,9,23,25-29,38H,8,10-22H2,1-4H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 UFRCJANXCPROEA-NVYQQUOZSA-N 630359 US20230340011, Example 659. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630359&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311898 485657926 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342217 COc1cncc(c1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O3/c1-23(5-10-32(39)37-17-15-36(16-18-37)25-20-27(40-4)22-35-21-25)29-8-9-30-28-7-6-24-19-26(38)11-13-33(24,2)31(28)12-14-34(29,30)3/h6,20-23,26,28-31,38H,5,7-19H2,1-4H3/t23-,26+,28+,29-,30+,31+,33+,34-/m1/s1 MNQDRVRZMJCTBW-WCECHVPBSA-N 630360 US20230340011, Example 660. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630360&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312557 485657927 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342219 C[C@H](CCC(=O)N1CCN(CC1)c1cncc(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H51N3O2/c1-23-19-26(22-35-21-23)36-15-17-37(18-16-36)32(39)10-5-24(2)29-8-9-30-28-7-6-25-20-27(38)11-13-33(25,3)31(28)12-14-34(29,30)4/h6,19,21-22,24,27-31,38H,5,7-18,20H2,1-4H3/t24-,27+,28+,29-,30+,31+,33+,34-/m1/s1 VENNXGHQGBPMFV-LLHZKFLPSA-N 630361 US20230340011, Example 661. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630361&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312367 485657928 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342221 COc1cncc(n1)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-31(39)37-17-15-36(16-18-37)29-20-34-21-30(35-29)40-4)26-8-9-27-25-7-6-23-19-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h6,20-22,24-28,38H,5,7-19H2,1-4H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 HSLGSFSCJAEMKD-WKFLPMMISA-N 630362 US20230340011, Example 662. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630362&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312076 485657929 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342223 C[C@H](CCC(=O)N1CCN(CC1)c1cc(ncn1)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H53N5O2/c1-23(6-11-32(41)39-18-16-38(17-19-39)31-21-30(37(4)5)35-22-36-31)27-9-10-28-26-8-7-24-20-25(40)12-14-33(24,2)29(26)13-15-34(27,28)3/h7,21-23,25-29,40H,6,8-20H2,1-5H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 HWMXPPJBOAYURZ-NVYQQUOZSA-N 630363 US20230340011, Example 663. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630363&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312467 485657930 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341467 COC(=O)N1CCN(CC1)C(=O)NC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H47N3O4/c1-19(18-30-26(34)31-13-15-32(16-14-31)27(35)36-4)23-7-8-24-22-6-5-20-17-21(33)9-11-28(20,2)25(22)10-12-29(23,24)3/h5,19,21-25,33H,6-18H2,1-4H3,(H,30,34)/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 PCWWWYUYYWJLQQ-YIZNBMETSA-N 629937 US20230340011, Example 236.::US20230340011, Example 467. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629937&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312509 485657602 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341470 COC(=O)N1CCN(CC1)C(=O)OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H46N2O5/c1-19(18-36-27(34)31-15-13-30(14-16-31)26(33)35-4)23-7-8-24-22-6-5-20-17-21(32)9-11-28(20,2)25(22)10-12-29(23,24)3/h5,19,21-25,32H,6-18H2,1-4H3/t19-,21+,22+,23-,24+,25+,28+,29-/m1/s1 GTTCGLAKJVFWSD-YIZNBMETSA-N 629939 US20230340011, Example 238.::US20230340011, Example 465. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629939&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312680 485657604 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341478 C[C@H](CCC(=O)N1CCN(CC1)C(C)=N)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49N3O2/c1-20(5-10-28(35)33-17-15-32(16-18-33)21(2)31)25-8-9-26-24-7-6-22-19-23(34)11-13-29(22,3)27(24)12-14-30(25,26)4/h6,20,23-27,31,34H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,29+,30-/m1/s1 RTTLJUZTQMAHTD-CMZGQUJUSA-N 629946 US20230340011, Example 245.::US20230340011, Example 459. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629946&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312124 485657611 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341480 C[C@H](CCc1ncccc1OCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H45NO3/c1-20(6-11-27-28(34-18-17-32)5-4-16-31-27)24-9-10-25-23-8-7-21-19-22(33)12-14-29(21,2)26(23)13-15-30(24,25)3/h4-5,7,16,20,22-26,32-33H,6,8-15,17-19H2,1-3H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 MBCIUIFIPBRQCG-RFWRZFGQSA-N 629947 US20230340011, Example 246. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629947&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312514 485657612 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341482 CCOc1cccnc1CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H45NO2/c1-5-33-28-7-6-18-31-27(28)13-8-20(2)24-11-12-25-23-10-9-21-19-22(32)14-16-29(21,3)26(23)15-17-30(24,25)4/h6-7,9,18,20,22-26,32H,5,8,10-17,19H2,1-4H3/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 KPNCKWIPTNGMEO-RFWRZFGQSA-N 629948 US20230340011, Example 247.::US20230340011, Example 457.::US20230340011, Example 458. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629948&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312018 485657613 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341484 C[C@H](CCc1ncccc1C(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H47NO2/c1-20(8-13-28-27(29(2,3)34)7-6-18-32-28)24-11-12-25-23-10-9-21-19-22(33)14-16-30(21,4)26(23)15-17-31(24,25)5/h6-7,9,18,20,22-26,33-34H,8,10-17,19H2,1-5H3/t20-,22+,23+,24-,25+,26+,30+,31-/m1/s1 OGIATJNVLIWGCR-HCJGDWAISA-N 629949 US20230340011, Example 248.::US20230340011, Example 456. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629949&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312009 485657614 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341486 C[C@H](CCc1ncccc1C(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H45NO2/c1-19(7-12-28-23(20(2)32)6-5-17-31-28)25-10-11-26-24-9-8-21-18-22(33)13-15-29(21,3)27(24)14-16-30(25,26)4/h5-6,8,17,19-20,22,24-27,32-33H,7,9-16,18H2,1-4H3/t19-,20?,22+,24+,25-,26+,27+,29+,30-/m1/s1 DSAIHBOVBTWQFB-LPCIFWECSA-N 629950 US20230340011, Example 249.::US20230340011, Example 455. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629950&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312916 485657615 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341488 C[C@H](CCc1ncccc1CO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H43NO2/c1-19(6-11-27-20(18-31)5-4-16-30-27)24-9-10-25-23-8-7-21-17-22(32)12-14-28(21,2)26(23)13-15-29(24,25)3/h4-5,7,16,19,22-26,31-32H,6,8-15,17-18H2,1-3H3/t19-,22+,23+,24-,25+,26+,28+,29-/m1/s1 ZZDJDMMSFPXVHM-HSIBUNQISA-N 629951 US20230340011, Example 250.::US20230340011, Example 454. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629951&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312446 485657616 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341490 C[C@H](CCC(=O)N1CCC(CC1)OC(F)(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H46F3NO3/c1-19(4-9-27(36)34-16-12-22(13-17-34)37-30(31,32)33)24-7-8-25-23-6-5-20-18-21(35)10-14-28(20,2)26(23)11-15-29(24,25)3/h5,19,21-26,35H,4,6-18H2,1-3H3/t19-,21+,23+,24-,25+,26+,28+,29-/m1/s1 DWYMQLFUQAQOBG-KHMNCEKASA-N 629952 US20230340011, Example 251.::US20230340011, Example 453. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629952&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312224 485657617 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341492 C[C@H](CCC(=O)N1CCC(CC1)OC(F)F)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H47F2NO3/c1-19(4-9-27(35)33-16-12-22(13-17-33)36-28(31)32)24-7-8-25-23-6-5-20-18-21(34)10-14-29(20,2)26(23)11-15-30(24,25)3/h5,19,21-26,28,34H,4,6-18H2,1-3H3/t19-,21+,23+,24-,25+,26+,29+,30-/m1/s1 LJMWOVNHXXOCQR-KIGGCCEQSA-N 629953 US20230340011, Example 252.::US20230340011, Example 452. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629953&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312686 485657618 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341494 CNC(=O)c1cccnc1OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H42N2O3/c1-18(17-34-27-22(26(33)30-4)6-5-15-31-27)23-9-10-24-21-8-7-19-16-20(32)11-13-28(19,2)25(21)12-14-29(23,24)3/h5-7,15,18,20-21,23-25,32H,8-14,16-17H2,1-4H3,(H,30,33)/t18-,20+,21+,23-,24+,25+,28+,29-/m1/s1 DUJIOAYQHYTAHP-QLEUTBLDSA-N 629954 US20230340011, Example 253.::US20230340011, Example 451. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629954&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312031 485657619 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341497 CNC(=O)c1ccc(OC[C@@H](C)[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)nc1 InChI=1S/C29H42N2O3/c1-18(17-34-26-10-5-19(16-31-26)27(33)30-4)23-8-9-24-22-7-6-20-15-21(32)11-13-28(20,2)25(22)12-14-29(23,24)3/h5-6,10,16,18,21-25,32H,7-9,11-15,17H2,1-4H3,(H,30,33)/t18-,21+,22+,23-,24+,25+,28+,29-/m1/s1 TYDCOVHTGVPQGO-GZDCHJOESA-N 629956 US20230340011, Example 255.::US20230340011, Example 449. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629956&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312528 485657621 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341500 COC1=C2C[C@@H](O)CC[C@]2(C)[C@H]2CC[C@]3(C)[C@H](CC[C@H]3[C@@H]2C1)[C@H](C)COc1ncccc1CO InChI=1S/C29H43NO4/c1-18(17-34-27-19(16-31)6-5-13-30-27)22-7-8-23-21-15-26(33-4)25-14-20(32)9-11-29(25,3)24(21)10-12-28(22,23)2/h5-6,13,18,20-24,31-32H,7-12,14-17H2,1-4H3/t18-,20+,21+,22-,23+,24+,28-,29-/m1/s1 CMBRKTLQQIQDJK-ILSIURKHSA-N 629958 US20230340011, Example 257. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629958&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312547 485657623 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341502 C[C@H](COc1cc(CO)ccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO3/c1-18(17-32-26-14-19(16-30)10-13-29-26)23-6-7-24-22-5-4-20-15-21(31)8-11-27(20,2)25(22)9-12-28(23,24)3/h4,10,13-14,18,21-25,30-31H,5-9,11-12,15-17H2,1-3H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 CCFRUMFQTIPSGM-JBZGATTQSA-N 629959 US20230340011, Example 258.::US20230340011, Example 446. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629959&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312597 485657624 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341505 C[C@H](COc1cccc(CO)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO3/c1-18(17-32-26-6-4-5-20(16-30)29-26)23-9-10-24-22-8-7-19-15-21(31)11-13-27(19,2)25(22)12-14-28(23,24)3/h4-7,18,21-25,30-31H,8-17H2,1-3H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 ICXOUWGBSVIOAJ-JBZGATTQSA-N 629961 US20230340011, Example 260.::US20230340011, Example 444. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629961&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312346 485657626 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341507 C[C@H](COc1ncccc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO2/c1-18-6-5-15-29-26(18)31-17-19(2)23-9-10-24-22-8-7-20-16-21(30)11-13-27(20,3)25(22)12-14-28(23,24)4/h5-7,15,19,21-25,30H,8-14,16-17H2,1-4H3/t19-,21+,22+,23-,24+,25+,27+,28-/m1/s1 LTSIUPLOJMIKEM-JDTILAPWSA-N 629962 US20230340011, Example 261.::US20230340011, Example 443. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629962&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312064 485657627 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341511 C[C@H](COc1cccc(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C28H41NO2/c1-18(17-31-26-7-5-6-19(2)29-26)23-10-11-24-22-9-8-20-16-21(30)12-14-27(20,3)25(22)13-15-28(23,24)4/h5-8,18,21-25,30H,9-17H2,1-4H3/t18-,21+,22+,23-,24+,25+,27+,28-/m1/s1 PLIHXRWYKLMIOG-JBZGATTQSA-N 629965 US20230340011, Example 264.::US20230340011, Example 440. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629965&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312415 485657630 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342225 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CC(C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H53N3O3/c1-22-20-36(21-22)31(39)35-17-15-34(16-18-35)30(38)10-5-23(2)27-8-9-28-26-7-6-24-19-25(37)11-13-32(24,3)29(26)12-14-33(27,28)4/h6,22-23,25-29,37H,5,7-21H2,1-4H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 WEEVEOHTEYMQCH-ACBDEFBISA-N 630364 US20230340011, Example 664. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630364&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312257 485657931 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342227 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CC[C@@H]1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H53N3O3/c1-22(5-10-30(38)34-17-19-35(20-18-34)31(39)36-16-13-23(36)2)27-8-9-28-26-7-6-24-21-25(37)11-14-32(24,3)29(26)12-15-33(27,28)4/h6,22-23,25-29,37H,5,7-21H2,1-4H3/t22-,23+,25+,26+,27-,28+,29+,32+,33-/m1/s1 RVMWDERBRQEPFP-GBHBUJJPSA-N 630365 US20230340011, Example 665. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630365&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311961 485657932 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342229 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CCC[C@@H]1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H55N3O3/c1-23(7-12-31(39)35-18-20-36(21-19-35)32(40)37-17-5-6-24(37)2)28-10-11-29-27-9-8-25-22-26(38)13-15-33(25,3)30(27)14-16-34(28,29)4/h8,23-24,26-30,38H,5-7,9-22H2,1-4H3/t23-,24+,26+,27+,28-,29+,30+,33+,34-/m1/s1 HFVXAWZKYRJKLE-ZLDPOVOCSA-N 630366 US20230340011, Example 666. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630366&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312603 485657933 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1342231 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N1CC[C@@H](C)C1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H55N3O3/c1-23-13-16-37(22-23)32(40)36-19-17-35(18-20-36)31(39)10-5-24(2)28-8-9-29-27-7-6-25-21-26(38)11-14-33(25,3)30(27)12-15-34(28,29)4/h6,23-24,26-30,38H,5,7-22H2,1-4H3/t23-,24-,26+,27+,28-,29+,30+,33+,34-/m1/s1 SHYWKZMYKISGSM-ISTHMIOUSA-N 630367 US20230340011, Example 667. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630367&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312343 485657934 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341522 C[C@H](Oc1cccnc1C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H39NO2/c1-17-25(6-5-15-28-17)30-18(2)22-9-10-23-21-8-7-19-16-20(29)11-13-26(19,3)24(21)12-14-27(22,23)4/h5-7,15,18,20-24,29H,8-14,16H2,1-4H3/t18-,20-,21-,22+,23-,24-,26-,27+/m0/s1 AUCGFEVTLJHDTO-CNXJXGGASA-N 629975 US20230340011, Example 274.::US20230340011, Example 430. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629975&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312807 485657640 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341524 C[C@H](CCC(=O)N1CCN(C[C@H]1C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)33-17-16-32(22(3)34)19-21(33)2)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 JFBHEEOFHUHZGZ-CSEUGJBGSA-N 629976 US20230340011, Example 275. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629976&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312186 485657641 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341526 C[C@H](CCC(=O)N1CCN(C[C@@H]1C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)33-17-16-32(22(3)34)19-21(33)2)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21+,24+,25+,26-,27+,28+,30+,31-/m1/s1 JFBHEEOFHUHZGZ-BMYROFSPSA-N 629977 US20230340011, Example 276. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629977&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312011 485657642 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341528 C[C@H](CCC(=O)N1CCN([C@@H](C)C1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)32-16-17-33(22(3)34)21(2)19-32)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21+,24+,25+,26-,27+,28+,30+,31-/m1/s1 FAZIJNUCDJRALL-BMYROFSPSA-N 629978 US20230340011, Example 277.::US20230340011, Example 427. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629978&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311852 485657643 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341530 C[C@H](CCC(=O)N1CCN([C@H](C)C1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)32-16-17-33(22(3)34)21(2)19-32)26-9-10-27-25-8-7-23-18-24(35)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,20-21,24-28,35H,6,8-19H2,1-5H3/t20-,21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 FAZIJNUCDJRALL-CSEUGJBGSA-N 629979 US20230340011, Example 278.::US20230340011, Example 426. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629979&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312640 485657644 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341532 C[C@H](CCC(=O)N1CCN(CC1)C(=O)OC1COC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O5/c1-21(4-9-29(36)33-14-16-34(17-15-33)30(37)39-24-19-38-20-24)26-7-8-27-25-6-5-22-18-23(35)10-12-31(22,2)28(25)11-13-32(26,27)3/h5,21,23-28,35H,4,6-20H2,1-3H3/t21-,23+,25+,26-,27+,28+,31+,32-/m1/s1 WWHQPROZNSKGNO-UJWPGJPTSA-N 629980 US20230340011, Example 279.::US20230340011, Example 425. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629980&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312422 485657645 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341534 COCCOC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O5/c1-22(5-10-29(36)33-15-17-34(18-16-33)30(37)39-20-19-38-4)26-8-9-27-25-7-6-23-21-24(35)11-13-31(23,2)28(25)12-14-32(26,27)3/h6,22,24-28,35H,5,7-21H2,1-4H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 NMPIFQFHUSMKOP-XJGPRUKRSA-N 629981 US20230340011, Example 280.::US20230340011, Example 424. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629981&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312162 485657646 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341536 C[C@H](CCC(=O)N1CCN(CC1)C(=O)OCCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O5/c1-21(4-9-28(36)32-14-16-33(17-15-32)29(37)38-19-18-34)25-7-8-26-24-6-5-22-20-23(35)10-12-30(22,2)27(24)11-13-31(25,26)3/h5,21,23-27,34-35H,4,6-20H2,1-3H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 BYEHIRYKAZTFNE-MIXBDBMTSA-N 629982 US20230340011, Example 281. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629982&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312637 485657647 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341538 CCOC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O4/c1-5-37-29(36)33-18-16-32(17-19-33)28(35)11-6-21(2)25-9-10-26-24-8-7-22-20-23(34)12-14-30(22,3)27(24)13-15-31(25,26)4/h7,21,23-27,34H,5-6,8-20H2,1-4H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 NBOHNTGQPDPLQJ-MIXBDBMTSA-N 629983 US20230340011, Example 282.::US20230340011, Example 422. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629983&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312654 485657648 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341540 COC(=O)N1CCN(CC1)C(=O)CCC[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C29H46N2O4/c1-28-14-12-25-23(9-7-21-19-22(32)11-13-29(21,25)2)24(28)10-8-20(28)5-4-6-26(33)30-15-17-31(18-16-30)27(34)35-3/h7,20,22-25,32H,4-6,8-19H2,1-3H3/t20-,22-,23-,24-,25-,28+,29-/m0/s1 NIZMSDBCIKBAAK-AADPQPSGSA-N 629984 US20230340011, Example 283.::US20230340011, Example 421. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629984&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312615 485657649 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341542 CC[C@]1(O)CC[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3CC=C2C1)[C@H](C)CCC(=O)N1CCN(CC1)C(=O)OC InChI=1S/C32H52N2O4/c1-6-32(37)16-15-30(3)23(21-32)8-9-24-26-11-10-25(31(26,4)14-13-27(24)30)22(2)7-12-28(35)33-17-19-34(20-18-33)29(36)38-5/h8,22,24-27,37H,6-7,9-21H2,1-5H3/t22-,24+,25-,26+,27+,30+,31-,32+/m1/s1 JMIDLZLQUVTWFQ-YVPUZFGVSA-N 629985 US20230340011, Example 284.::US20230340011, Example 420. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629985&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312065 485657650 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341544 COC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@](O)(CC[C@]4(C)[C@H]3CC[C@]12C)C(F)(F)F InChI=1S/C31H47F3N2O4/c1-20(5-10-26(37)35-15-17-36(18-16-35)27(38)40-4)23-8-9-24-22-7-6-21-19-30(39,31(32,33)34)14-13-28(21,2)25(22)11-12-29(23,24)3/h6,20,22-25,39H,5,7-19H2,1-4H3/t20-,22+,23-,24+,25+,28+,29-,30+/m1/s1 PQBBZAIBPZNRGP-FWOOPTSHSA-N 629986 US20230340011, Example 285.::US20230340011, Example 419. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629986&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311924 485657651 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341546 C[C@H](CCC(=O)N1CCC(CC1)OC(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O4/c1-21(6-11-29(36)34-18-14-24(15-19-34)38-30(37)33(4)5)26-9-10-27-25-8-7-22-20-23(35)12-16-31(22,2)28(25)13-17-32(26,27)3/h7,21,23-28,35H,6,8-20H2,1-5H3/t21-,23+,25+,26-,27+,28+,31+,32-/m1/s1 WXPMWWZITWCFCE-UJWPGJPTSA-N 629987 US20230340011, Example 286.::US20230340011, Example 418. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629987&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311905 485657652 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341548 C[C@H](CCC(=O)N1CCC(CC1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O2/c1-23(4-9-32(38)36-20-14-25(15-21-36)24-12-18-35-19-13-24)29-7-8-30-28-6-5-26-22-27(37)10-16-33(26,2)31(28)11-17-34(29,30)3/h5,12-13,18-19,23,25,27-31,37H,4,6-11,14-17,20-22H2,1-3H3/t23-,27+,28+,29-,30+,31+,33+,34-/m1/s1 RZZWGGCRGMCXCD-AESKLMAPSA-N 629988 US20230340011, Example 287.::US20230340011, Example 417. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629988&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312648 485657653 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341550 C[C@H](CCC(=O)N1CCC(CC1)N(C)C(=O)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C36H53N3O3/c1-24(5-10-33(41)39-21-15-27(16-22-39)38(4)34(42)25-13-19-37-20-14-25)30-8-9-31-29-7-6-26-23-28(40)11-17-35(26,2)32(29)12-18-36(30,31)3/h6,13-14,19-20,24,27-32,40H,5,7-12,15-18,21-23H2,1-4H3/t24-,28+,29+,30-,31+,32+,35+,36-/m1/s1 RQWPRIOZCPAJJG-HKMDHWLPSA-N 629989 US20230340011, Example 288.::US20230340011, Example 416. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629989&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312620 485657654 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341552 C[C@H](CCC(=O)N1CCC(CC1)N(C)S(C)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O4S/c1-21(6-11-29(35)33-18-14-23(15-19-33)32(4)38(5,36)37)26-9-10-27-25-8-7-22-20-24(34)12-16-30(22,2)28(25)13-17-31(26,27)3/h7,21,23-28,34H,6,8-20H2,1-5H3/t21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 BIXNIUQKIIVIJX-ANSWHRQLSA-N 629990 US20230340011, Example 289.::US20230340011, Example 415. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629990&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312605 485657655 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341554 C[C@H](CCC(=O)N1CCC(CC1)S(=O)(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O4S/c1-21(6-11-29(35)33-18-14-24(15-19-33)38(36,37)32(4)5)26-9-10-27-25-8-7-22-20-23(34)12-16-30(22,2)28(25)13-17-31(26,27)3/h7,21,23-28,34H,6,8-20H2,1-5H3/t21-,23+,25+,26-,27+,28+,30+,31-/m1/s1 AZAMCAAZSQKHQX-KHGYUHDZSA-N 629991 US20230340011, Example 290.::US20230340011, Example 413. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629991&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312548 485657656 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341556 CNS(=O)(=O)C1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H50N2O4S/c1-20(5-10-28(34)32-17-13-23(14-18-32)37(35,36)31-4)25-8-9-26-24-7-6-21-19-22(33)11-15-29(21,2)27(24)12-16-30(25,26)3/h6,20,22-27,31,33H,5,7-19H2,1-4H3/t20-,22+,24+,25-,26+,27+,29+,30-/m1/s1 FWNUYAQNOAEZGO-UZKJJXDZSA-N 629992 US20230340011, Example 291.::US20230340011, Example 412. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629992&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312459 485657657 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341558 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1nc(C)no1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O4/c1-20(5-10-28(38)35-15-17-36(18-16-35)30(39)29-33-21(2)34-40-29)25-8-9-26-24-7-6-22-19-23(37)11-13-31(22,3)27(24)12-14-32(25,26)4/h6,20,23-27,37H,5,7-19H2,1-4H3/t20-,23+,24+,25-,26+,27+,31+,32-/m1/s1 BHQQMEQOZBLXLK-LDQJSCHESA-N 629993 US20230340011, Example 292.::US20230340011, Example 411. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312177 485657658 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341560 C[C@H](CCC(=O)N(C)CCc1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N2O2/c1-22(8-13-30(36)34(4)20-16-24-7-5-6-19-33-24)27-11-12-28-26-10-9-23-21-25(35)14-17-31(23,2)29(26)15-18-32(27,28)3/h5-7,9,19,22,25-29,35H,8,10-18,20-21H2,1-4H3/t22-,25+,26+,27-,28+,29+,31+,32-/m1/s1 MALABKVRPVMDNF-NWKCFVCZSA-N 629994 US20230340011, Example 293.::US20230340011, Example 409. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629994&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312614 485657659 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341564 C[C@H](CCC(=O)N(C)[C@H]1CC[C@@H](CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-31(38)36(6)25-11-8-23(9-12-25)32(39)35(4)5)28-14-15-29-27-13-10-24-21-26(37)17-19-33(24,2)30(27)18-20-34(28,29)3/h10,22-23,25-30,37H,7-9,11-21H2,1-6H3/t22-,23-,25-,26+,27+,28-,29+,30+,33+,34-/m1/s1 RVZOTPVQYDMLNP-HLPOEUGRSA-N 629997 US20230340011, Example 296. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629997&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311882 485657662 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341566 C[C@H](CCC(=O)N(C)[C@H]1CC[C@H](CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-31(38)36(6)25-11-8-23(9-12-25)32(39)35(4)5)28-14-15-29-27-13-10-24-21-26(37)17-19-33(24,2)30(27)18-20-34(28,29)3/h10,22-23,25-30,37H,7-9,11-21H2,1-6H3/t22-,23-,25+,26+,27+,28-,29+,30+,33+,34-/m1/s1 RVZOTPVQYDMLNP-ZAPRWDPSSA-N 629998 US20230340011, Example 297. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629998&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311882 485657663 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341568 C[C@H](CCC(=O)N(C)[C@H]1CC[C@@H](CC1)N(C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-32(39)36(6)26-11-9-25(10-12-26)35(5)23(2)37)29-14-15-30-28-13-8-24-21-27(38)17-19-33(24,3)31(28)18-20-34(29,30)4/h8,22,25-31,38H,7,9-21H2,1-6H3/t22-,25-,26-,27+,28+,29-,30+,31+,33+,34-/m1/s1 GMNIHTMJHRCHEM-ZHUPGQSKSA-N 629999 US20230340011, Example 298. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629999&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312452 485657664 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341570 C[C@H](CCC(=O)N(C)[C@H]1CC[C@@H](CC1)N(C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H56N2O3/c1-22(7-16-32(39)36(6)26-11-9-25(10-12-26)35(5)23(2)37)29-14-15-30-28-13-8-24-21-27(38)17-19-33(24,3)31(28)18-20-34(29,30)4/h8,22,25-31,38H,7,9-21H2,1-6H3/t22-,25-,26-,27+,28+,29-,30+,31+,33+,34-/m1/s1 GMNIHTMJHRCHEM-ZHUPGQSKSA-N 630000 US20230340011, Example 299. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630000&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312452 485657665 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341572 CO[C@H]1CCCN(C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO3/c1-20(7-12-28(33)31-17-5-6-23(19-31)34-4)25-10-11-26-24-9-8-21-18-22(32)13-15-29(21,2)27(24)14-16-30(25,26)3/h8,20,22-27,32H,5-7,9-19H2,1-4H3/t20-,22+,23+,24+,25-,26+,27+,29+,30-/m1/s1 AJPPENWWEOYGLC-DHXMEVIDSA-N 630001 US20230340011, Example 300.::US20230340011, Example 402. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630001&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312853 485657666 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341574 C[C@H](CCC(=O)N1CCC(CC1)Oc1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O3/c1-23(4-9-32(38)36-20-14-27(15-21-36)39-26-12-18-35-19-13-26)29-7-8-30-28-6-5-24-22-25(37)10-16-33(24,2)31(28)11-17-34(29,30)3/h5,12-13,18-19,23,25,27-31,37H,4,6-11,14-17,20-22H2,1-3H3/t23-,25+,28+,29-,30+,31+,33+,34-/m1/s1 SWEUQVPZTGVSBU-HJIUKPPKSA-N 630002 US20230340011, Example 301.::US20230340011, Example 401. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630002&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311917 485657667 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341576 C[C@H](CCC(=O)N1CCN(CC1)c1ccncn1)[C@@]1(I)CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H47IN4O2/c1-22(4-7-29(39)37-18-16-36(17-19-37)28-11-15-34-21-35-28)32(33)14-10-27-25-6-5-23-20-24(38)8-12-30(23,2)26(25)9-13-31(27,32)3/h5,11,15,21-22,24-27,38H,4,6-10,12-14,16-20H2,1-3H3/t22-,24+,25-,26+,27+,30+,31+,32+/m1/s1 COSLVWPZWGJLLI-ATKBKGHUSA-N 630003 US20230340011, Example 302. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630003&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311866 485657668 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341578 C[C@H](CCC(=O)N1CCN(CC1)c1cccnn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(6-11-30(38)36-19-17-35(18-20-36)29-5-4-16-33-34-29)26-9-10-27-25-8-7-23-21-24(37)12-14-31(23,2)28(25)13-15-32(26,27)3/h4-5,7,16,22,24-28,37H,6,8-15,17-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 HFQNLBNQTGYVQZ-XJGPRUKRSA-N 630004 US20230340011, Example 303.::US20230340011, Example 399. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630004&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312633 485657669 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341580 C[C@H](CCC(=O)N1CCN(CC1)c1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(4-9-30(38)36-18-16-35(17-19-36)29-21-33-14-15-34-29)26-7-8-27-25-6-5-23-20-24(37)10-12-31(23,2)28(25)11-13-32(26,27)3/h5,14-15,21-22,24-28,37H,4,6-13,16-20H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 USTRWUCCQNOIPP-XJGPRUKRSA-N 630005 US20230340011, Example 304.::US20230340011, Example 305.::US20230340011, Example 398. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630005&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311957 485657670 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341582 C[C@H](CCC(=O)N1CCN(CC1)c1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H48N4O2/c1-22(4-9-30(38)36-18-16-35(17-19-36)29-21-33-14-15-34-29)26-7-8-27-25-6-5-23-20-24(37)10-12-31(23,2)28(25)11-13-32(26,27)3/h5,14-15,21-22,24-28,37H,4,6-13,16-20H2,1-3H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 USTRWUCCQNOIPP-XJGPRUKRSA-N 630005 US20230340011, Example 304.::US20230340011, Example 305.::US20230340011, Example 398. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630005&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311957 485657670 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341584 C[C@H](CCC(=O)N1CCN(CC1)c1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O2/c1-23(6-11-31(38)36-19-17-35(18-20-36)25-5-4-16-34-22-25)28-9-10-29-27-8-7-24-21-26(37)12-14-32(24,2)30(27)13-15-33(28,29)3/h4-5,7,16,22-23,26-30,37H,6,8-15,17-21H2,1-3H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 FYWJALJKZHBWQH-ZWWVIQJBSA-N 630007 US20230340011, Example 306.::US20230340011, Example 395. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630007&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312697 485657671 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341586 C[C@H](CCC(=O)N1CCN(CC1)c1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H49N3O2/c1-23(7-12-31(38)36-20-18-35(19-21-36)30-6-4-5-17-34-30)27-10-11-28-26-9-8-24-22-25(37)13-15-32(24,2)29(26)14-16-33(27,28)3/h4-6,8,17,23,25-29,37H,7,9-16,18-22H2,1-3H3/t23-,25+,26+,27-,28+,29+,32+,33-/m1/s1 YPDZZGTWIGIMJD-ACBDEFBISA-N 630008 US20230340011, Example 307.::US20230340011, Example 394. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630008&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312448 485657672 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341588 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cn(C)nn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H49N5O3/c1-21(5-10-29(39)36-15-17-37(18-16-36)30(40)28-20-35(4)34-33-28)25-8-9-26-24-7-6-22-19-23(38)11-13-31(22,2)27(24)12-14-32(25,26)3/h6,20-21,23-27,38H,5,7-19H2,1-4H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 ZEIGNTCDPVULKY-GTORSBDHSA-N 630009 US20230340011, Example 308.::US20230340011, Example 393. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630009&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312215 485657673 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341590 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cnn(C)c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H50N4O3/c1-22(5-10-30(39)36-15-17-37(18-16-36)31(40)23-20-34-35(4)21-23)27-8-9-28-26-7-6-24-19-25(38)11-13-32(24,2)29(26)12-14-33(27,28)3/h6,20-22,25-29,38H,5,7-19H2,1-4H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 DQGMTMJCVJHZGV-VEQXFWRMSA-N 630010 US20230340011, Example 309.::US20230340011, Example 392.::US20230340011, Example 565. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630010&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312775 485657674 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341592 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cn[nH]c1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C 630011 US20230340011, Example 310.::US20230340011, Example 391. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630011&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312250 485657675 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341594 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ccns1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H47N3O3S/c1-21(4-9-29(37)34-16-18-35(19-17-34)30(38)28-12-15-33-39-28)25-7-8-26-24-6-5-22-20-23(36)10-13-31(22,2)27(24)11-14-32(25,26)3/h5,12,15,21,23-27,36H,4,6-11,13-14,16-20H2,1-3H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 MDLMAXAHXWCDIA-GTORSBDHSA-N 630012 US20230340011, Example 311.::US20230340011, Example 390. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630012&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312643 485657676 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341596 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ccnnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H48N4O3/c1-22(4-9-30(39)36-16-18-37(19-17-36)31(40)23-12-15-34-35-21-23)27-7-8-28-26-6-5-24-20-25(38)10-13-32(24,2)29(26)11-14-33(27,28)3/h5,12,15,21-22,25-29,38H,4,6-11,13-14,16-20H2,1-3H3/t22-,25+,26+,27-,28+,29+,32+,33-/m1/s1 TZUFFUTYMSFLIM-VEQXFWRMSA-N 630013 US20230340011, Example 312.::US20230340011, Example 389. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630013&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312569 485657677 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341598 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cccnc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H49N3O3/c1-23(6-11-31(39)36-17-19-37(20-18-36)32(40)24-5-4-16-35-22-24)28-9-10-29-27-8-7-25-21-26(38)12-14-33(25,2)30(27)13-15-34(28,29)3/h4-5,7,16,22-23,26-30,38H,6,8-15,17-21H2,1-3H3/t23-,26+,27+,28-,29+,30+,33+,34-/m1/s1 WSSPERYQWHNBTM-WACGHZNISA-N 630014 US20230340011, Example 313.::US20230340011, Example 388. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630014&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312741 485657678 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341600 C[C@H](CCC(=O)N1CCN(CC1)C(=O)C1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O3/c1-21(4-11-29(36)33-16-18-34(19-17-33)30(37)22-5-6-22)26-9-10-27-25-8-7-23-20-24(35)12-14-31(23,2)28(25)13-15-32(26,27)3/h7,21-22,24-28,35H,4-6,8-20H2,1-3H3/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 VEGJZBOTMLUQOF-XKQUNUCNSA-N 630015 US20230340011, Example 314.::US20230340011, Example 387. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630015&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312070 485657679 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341602 CC(C)C(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-21(2)30(37)34-18-16-33(17-19-34)29(36)11-6-22(3)26-9-10-27-25-8-7-23-20-24(35)12-14-31(23,4)28(25)13-15-32(26,27)5/h7,21-22,24-28,35H,6,8-20H2,1-5H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 FCPBOBNQKUTZSE-XJGPRUKRSA-N 630016 US20230340011, Example 315.::US20230340011, Example 386. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630016&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312293 485657680 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341604 CC(C)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H52N2O2/c1-21(2)32-16-18-33(19-17-32)29(35)11-6-22(3)26-9-10-27-25-8-7-23-20-24(34)12-14-30(23,4)28(25)13-15-31(26,27)5/h7,21-22,24-28,34H,6,8-20H2,1-5H3/t22-,24+,25+,26-,27+,28+,30+,31-/m1/s1 LMUISNHLOQMMOS-GTPODGLVSA-N 630017 US20230340011, Example 316. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630017&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312585 485657681 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341606 C[C@H](CCC(=O)N1CCCN(CC1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-21(6-11-29(36)33-17-5-16-32(18-19-33)22(2)34)26-9-10-27-25-8-7-23-20-24(35)12-14-30(23,3)28(25)13-15-31(26,27)4/h7,21,24-28,35H,5-6,8-20H2,1-4H3/t21-,24+,25+,26-,27+,28+,30+,31-/m1/s1 GMJUIHLAXPMSFI-ANSWHRQLSA-N 630018 US20230340011, Example 317. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630018&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312859 485657682 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341608 C[C@H](CCC(=O)N1C[C@@H]2CN(C[C@@H]2C1)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O3/c1-20(5-10-30(37)34-18-22-16-33(21(2)35)17-23(22)19-34)27-8-9-28-26-7-6-24-15-25(36)11-13-31(24,3)29(26)12-14-32(27,28)4/h6,20,22-23,25-29,36H,5,7-19H2,1-4H3/t20-,22-,23+,25+,26+,27-,28+,29+,31+,32-/m1/s1 BVOPUUMHEOLTRQ-CEZAYEQDSA-N 630019 US20230340011, Example 318. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630019&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312482 485657683 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341610 C[C@H](CCC(=O)N1CCC(CC1)N(C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O3/c1-21(6-11-30(37)34-18-14-24(15-19-34)33(5)22(2)35)27-9-10-28-26-8-7-23-20-25(36)12-16-31(23,3)29(26)13-17-32(27,28)4/h7,21,24-29,36H,6,8-20H2,1-5H3/t21-,25+,26+,27-,28+,29+,31+,32-/m1/s1 WKQVLMGFKVWNSF-KNLNLFKVSA-N 630020 US20230340011, Example 319. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630020&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311998 485657684 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341612 C[C@H](CCC(=O)N1CCC(CC1)NC(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(5-10-29(36)33-17-13-23(14-18-33)32-21(2)34)26-8-9-27-25-7-6-22-19-24(35)11-15-30(22,3)28(25)12-16-31(26,27)4/h6,20,23-28,35H,5,7-19H2,1-4H3,(H,32,34)/t20-,24+,25+,26-,27+,28+,30+,31-/m1/s1 PPCIUVDBPZSNLA-OZCBFACLSA-N 630021 US20230340011, Example 320. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630021&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312776 485657685 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341614 C[C@H](CCC(=O)N1CC[C@@H](C1)N(C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)33-17-14-23(19-33)32(5)21(2)34)26-9-10-27-25-8-7-22-18-24(35)12-15-30(22,3)28(25)13-16-31(26,27)4/h7,20,23-28,35H,6,8-19H2,1-5H3/t20-,23+,24+,25+,26-,27+,28+,30+,31-/m1/s1 VOKYRWZXWXALHC-YJLGMCLASA-N 630022 US20230340011, Example 321. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630022&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311937 485657686 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341616 C[C@H](CCC(=O)N1CC[C@@H](C1)NC(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N2O3/c1-19(5-10-28(35)32-16-13-22(18-32)31-20(2)33)25-8-9-26-24-7-6-21-17-23(34)11-14-29(21,3)27(24)12-15-30(25,26)4/h6,19,22-27,34H,5,7-18H2,1-4H3,(H,31,33)/t19-,22+,23+,24+,25-,26+,27+,29+,30-/m1/s1 MEEMZOWHGOIOFR-WLRBMJDBSA-N 630023 US20230340011, Example 322. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630023&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312440 485657687 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341618 C[C@H](CCC(=O)N1CC[C@H](C1)N(C)C(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H50N2O3/c1-20(6-11-29(36)33-17-14-23(19-33)32(5)21(2)34)26-9-10-27-25-8-7-22-18-24(35)12-15-30(22,3)28(25)13-16-31(26,27)4/h7,20,23-28,35H,6,8-19H2,1-5H3/t20-,23-,24+,25+,26-,27+,28+,30+,31-/m1/s1 VOKYRWZXWXALHC-UMUAKTDISA-N 630024 US20230340011, Example 323. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630024&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312113 485657688 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341620 C[C@H](CCC(=O)N1CC[C@H](C1)NC(C)=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H48N2O3/c1-19(5-10-28(35)32-16-13-22(18-32)31-20(2)33)25-8-9-26-24-7-6-21-17-23(34)11-14-29(21,3)27(24)12-15-30(25,26)4/h6,19,22-27,34H,5,7-18H2,1-4H3,(H,31,33)/t19-,22-,23+,24+,25-,26+,27+,29+,30-/m1/s1 MEEMZOWHGOIOFR-OODDMRAHSA-N 630025 US20230340011, Example 324. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630025&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311864 485657689 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341626 CC(C)OC1(CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C#C InChI=1S/C34H53NO3/c1-7-34(38-23(2)3)18-20-35(21-19-34)31(37)13-8-24(4)28-11-12-29-27-10-9-25-22-26(36)14-16-32(25,5)30(27)15-17-33(28,29)6/h1,9,23-24,26-30,36H,8,10-22H2,2-6H3/t24-,26+,27+,28-,29+,30+,32+,33-/m1/s1 CONSXHMHTBZJDC-FLFWOSPYSA-N 630030 US20230340011, Example 329. Oxysterols receptor LXR-beta 5500 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630030&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312405 485657694 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341628 COC1(CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C#C InChI=1S/C32H49NO3/c1-6-32(36-5)17-19-33(20-18-32)29(35)12-7-22(2)26-10-11-27-25-9-8-23-21-24(34)13-15-30(23,3)28(25)14-16-31(26,27)4/h1,8,22,24-28,34H,7,9-21H2,2-5H3/t22-,24+,25+,26-,27+,28+,30+,31-/m1/s1 FSXSVMWOIJNOPA-GTPODGLVSA-N 630031 US20230340011, Example 330. Oxysterols receptor LXR-beta 625 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630031&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312830 485657695 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341630 COC([C@@H]1CCN(C1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)(C(F)(F)F)C(F)(F)F InChI=1S/C32H47F6NO3/c1-19(5-10-27(41)39-16-13-21(18-39)30(42-4,31(33,34)35)32(36,37)38)24-8-9-25-23-7-6-20-17-22(40)11-14-28(20,2)26(23)12-15-29(24,25)3/h6,19,21-26,40H,5,7-18H2,1-4H3/t19-,21-,22+,23+,24-,25+,26+,28+,29-/m1/s1 DXSFIFJUHHUJSQ-FZCUBFCVSA-N 629800 US20230340011, Example 331. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=629800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=629800&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312046 485657466 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341632 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ncccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H48N4O3/c1-22(5-10-29(39)36-17-19-37(20-18-36)31(40)30-34-15-4-16-35-30)26-8-9-27-25-7-6-23-21-24(38)11-13-32(23,2)28(25)12-14-33(26,27)3/h4,6,15-16,22,24-28,38H,5,7-14,17-21H2,1-3H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 FPLSLMWALISPEL-WKFLPMMISA-N 630033 US20230340011, Example 332. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630033&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312146 485657697 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341634 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1cnccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H48N4O3/c1-22(4-9-30(39)36-16-18-37(19-17-36)31(40)29-21-34-14-15-35-29)26-7-8-27-25-6-5-23-20-24(38)10-12-32(23,2)28(25)11-13-33(26,27)3/h5,14-15,21-22,24-28,38H,4,6-13,16-20H2,1-3H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 JKYUWUPTTJOGDV-WKFLPMMISA-N 630034 US20230340011, Example 333. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630034&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312209 485657698 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341636 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ccncn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C33H48N4O3/c1-22(4-9-30(39)36-16-18-37(19-17-36)31(40)29-12-15-34-21-35-29)26-7-8-27-25-6-5-23-20-24(38)10-13-32(23,2)28(25)11-14-33(26,27)3/h5,12,15,21-22,24-28,38H,4,6-11,13-14,16-20H2,1-3H3/t22-,24+,25+,26-,27+,28+,32+,33-/m1/s1 HQWLALWVMJPNOT-WKFLPMMISA-N 630035 US20230340011, Example 334. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630035&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312419 485657699 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341638 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1ccccn1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H49N3O3/c1-23(7-12-31(39)36-18-20-37(21-19-36)32(40)30-6-4-5-17-35-30)27-10-11-28-26-9-8-24-22-25(38)13-15-33(24,2)29(26)14-16-34(27,28)3/h4-6,8,17,23,25-29,38H,7,9-16,18-22H2,1-3H3/t23-,25+,26+,27-,28+,29+,33+,34-/m1/s1 KRYHBMUTYYQLKX-NVYQQUOZSA-N 630036 US20230340011, Example 335. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630036&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312751 485657700 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341640 C[C@H](CCC(=O)N1CCN(CC1)C(=O)C(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O4/c1-21(6-11-28(36)33-16-18-34(19-17-33)29(37)30(2,3)38)25-9-10-26-24-8-7-22-20-23(35)12-14-31(22,4)27(24)13-15-32(25,26)5/h7,21,23-27,35,38H,6,8-20H2,1-5H3/t21-,23+,24+,25-,26+,27+,31+,32-/m1/s1 PDFAOUGZYAWKFM-GTORSBDHSA-N 630037 US20230340011, Example 336. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630037&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311953 485657701 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341642 CNC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49N3O3/c1-20(5-10-27(35)32-15-17-33(18-16-32)28(36)31-4)24-8-9-25-23-7-6-21-19-22(34)11-13-29(21,2)26(23)12-14-30(24,25)3/h6,20,22-26,34H,5,7-19H2,1-4H3,(H,31,36)/t20-,22+,23+,24-,25+,26+,29+,30-/m1/s1 HZMJHKQWYWCMBB-RFWRZFGQSA-N 630038 US20230340011, Example 337. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630038&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312183 485657702 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341644 C[C@H](CCC(=O)N1CCN(CC1)C(=O)NC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H51N3O3/c1-21(4-11-29(37)34-16-18-35(19-17-34)30(38)33-23-6-7-23)26-9-10-27-25-8-5-22-20-24(36)12-14-31(22,2)28(25)13-15-32(26,27)3/h5,21,23-28,36H,4,6-20H2,1-3H3,(H,33,38)/t21-,24+,25+,26-,27+,28+,31+,32-/m1/s1 IFHHTFJKJZAQLH-XKQUNUCNSA-N 630039 US20230340011, Example 338. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630039&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311889 485657703 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341646 C[C@H](CCC(=O)N1CCN(CC1)C(=O)N(C)C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H51N3O3/c1-21(6-11-28(36)33-16-18-34(19-17-33)29(37)32(4)5)25-9-10-26-24-8-7-22-20-23(35)12-14-30(22,2)27(24)13-15-31(25,26)3/h7,21,23-27,35H,6,8-20H2,1-5H3/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1 RCEVQTCWMKWDOM-MIXBDBMTSA-N 630040 US20230340011, Example 339. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630040&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312306 485657704 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341648 C[C@H](CCC(=O)N1CCN(CC1)C(=O)OC1CC1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H50N2O4/c1-21(4-11-29(36)33-16-18-34(19-17-33)30(37)38-24-6-7-24)26-9-10-27-25-8-5-22-20-23(35)12-14-31(22,2)28(25)13-15-32(26,27)3/h5,21,23-28,35H,4,6-20H2,1-3H3/t21-,23+,25+,26-,27+,28+,31+,32-/m1/s1 MNVLYXVQYVXCCI-UJWPGJPTSA-N 630041 US20230340011, Example 340. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630041&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312407 485657705 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341650 CC(C)OC(=O)N1CCN(CC1)C(=O)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C32H52N2O4/c1-21(2)38-30(37)34-18-16-33(17-19-34)29(36)11-6-22(3)26-9-10-27-25-8-7-23-20-24(35)12-14-31(23,4)28(25)13-15-32(26,27)5/h7,21-22,24-28,35H,6,8-20H2,1-5H3/t22-,24+,25+,26-,27+,28+,31+,32-/m1/s1 CZWAWSQQPLNSSP-XJGPRUKRSA-N 630042 US20230340011, Example 341. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630042&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312273 485657706 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341652 C[C@H](CCC(=O)N1CCN(CC1)C(=O)c1nnn(C)n1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C31H48N6O3/c1-20(5-10-27(39)36-15-17-37(18-16-36)29(40)28-32-34-35(4)33-28)24-8-9-25-23-7-6-21-19-22(38)11-13-30(21,2)26(23)12-14-31(24,25)3/h6,20,22-26,38H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,30+,31-/m1/s1 QUSHAFWLXXBCIG-HCJGDWAISA-N 630043 US20230340011, Example 342. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630043&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312465 485657707 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341655 C[C@H](CCC(=O)N1CCC(O)(CC1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O3/c1-23(4-9-31(38)36-20-16-34(39,17-21-36)24-12-18-35-19-13-24)28-7-8-29-27-6-5-25-22-26(37)10-14-32(25,2)30(27)11-15-33(28,29)3/h5,12-13,18-19,23,26-30,37,39H,4,6-11,14-17,20-22H2,1-3H3/t23-,26+,27+,28-,29+,30+,32+,33-/m1/s1 ZSUGHVWPBVJCFG-ZWWVIQJBSA-N 630045 US20230340011, Example 344. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630045&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312926 485657709 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341658 C[C@H](CCC(=O)N1CCCC(C1)c1ccncc1)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C34H50N2O2/c1-23(6-11-32(38)36-20-4-5-25(22-36)24-14-18-35-19-15-24)29-9-10-30-28-8-7-26-21-27(37)12-16-33(26,2)31(28)13-17-34(29,30)3/h7,14-15,18-19,23,25,27-31,37H,4-6,8-13,16-17,20-22H2,1-3H3/t23-,25?,27+,28+,29-,30+,31+,33+,34-/m1/s1 YLHMEFUTYZUWEM-BSWJUSAPSA-N 630047 US20230340011, Example 346. Oxysterols receptor LXR-beta 125 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630047&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312369 485657711 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341661 CCC1(O)CCN(CC1)C(=O)OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C30H49NO4/c1-5-30(34)14-16-31(17-15-30)27(33)35-19-20(2)24-8-9-25-23-7-6-21-18-22(32)10-12-28(21,3)26(23)11-13-29(24,25)4/h6,20,22-26,32,34H,5,7-19H2,1-4H3/t20-,22+,23+,24-,25+,26+,28+,29-/m1/s1 UJLVQFNWMABCGC-OHPSOFBHSA-N 630049 US20230340011, Example 348. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630049&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312322 485657713 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341663 COCCN(C)C(=O)OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H45NO4/c1-18(17-32-25(30)28(4)14-15-31-5)22-8-9-23-21-7-6-19-16-20(29)10-12-26(19,2)24(21)11-13-27(22,23)3/h6,18,20-24,29H,7-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1 WOGDGXXYUDKYRV-ZHHJOTBYSA-N 630050 US20230340011, Example 349. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630050&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312227 485657714 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341665 C[C@H](COC(=O)N(C)CCO)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C26H43NO4/c1-17(16-31-24(30)27(4)13-14-28)21-7-8-22-20-6-5-18-15-19(29)9-11-25(18,2)23(20)10-12-26(21,22)3/h5,17,19-23,28-29H,6-16H2,1-4H3/t17-,19+,20+,21-,22+,23+,25+,26-/m1/s1 AEMLPRANVMKJCO-LXVLQKCJSA-N 630051 US20230340011, Example 350. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630051&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169311903 485657715 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 1341667 CNC(=O)OC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C24H39NO3/c1-15(14-28-22(27)25-4)19-7-8-20-18-6-5-16-13-17(26)9-11-23(16,2)21(18)10-12-24(19,20)3/h5,15,17-21,26H,6-14H2,1-4H3,(H,25,27)/t15-,17+,18+,19-,20+,21+,23+,24-/m1/s1 HLCAPEGWVBFPEM-QIZZZRFXSA-N 630052 US20230340011, Example 351. Oxysterols receptor LXR-beta >10000 US Patent 10.7270/Q2RV0SVS US20230340011 Feula, A; Salituro, FG; Stites, RE Asteroid Therapeutics http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=630052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=630052&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 169312806 485657716 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51530235 CCOC(=O)c1ccc(CN(Cc2ccc(cc2)-c2cccc(c2)S(C)(=O)=O)S(=O)(=O)c2c(C)cc(C)cc2C)o1 InChI=1S/C31H33NO7S2/c1-6-38-31(33)29-15-14-27(39-29)20-32(41(36,37)30-22(3)16-21(2)17-23(30)4)19-24-10-12-25(13-11-24)26-8-7-9-28(18-26)40(5,34)35/h7-18H,6,19-20H2,1-5H3 HDZWHJYZJWLTAG-UHFFFAOYSA-N 50465712 CHEMBL4284414 Oxysterols receptor LXR-beta 43 ChEMBL 10.7270/Q2Z03DDS 32339855 Yang, Y; Zhao, Y; Li, W; Wu, Y; Wang, X; Wang, Y; Liu, T; Ye, T; Xie, Y; Cheng, Z; He, J; Bai, P; Zhang, Y; Ouyang, L Sichuan University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465712&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 71478195 433932977 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51545946 OC(=O)Cc1ccc(cc1)-c1ccc(OCc2c(onc2-c2c(Cl)cccc2Cl)C2CC2)cc1 InChI=1S/C27H21Cl2NO4/c28-22-2-1-3-23(29)25(22)26-21(27(34-30-26)19-8-9-19)15-33-20-12-10-18(11-13-20)17-6-4-16(5-7-17)14-24(31)32/h1-7,10-13,19H,8-9,14-15H2,(H,31,32) AJXYOQYFSSSTMZ-UHFFFAOYSA-N 50621751 CHEMBL5420532 Oxysterols receptor LXR-beta Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.2c01918 10.7270/Q2028WWR 37079895 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50621751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50621751&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51545947 CCc1c(c(nn1-c1ccccc1-c1cccc(OCC(O)=O)c1)-c1ccccc1)-c1ccccc1 InChI=1S/C31H26N2O3/c1-2-27-30(22-12-5-3-6-13-22)31(23-14-7-4-8-15-23)32-33(27)28-19-10-9-18-26(28)24-16-11-17-25(20-24)36-21-29(34)35/h3-20H,2,21H2,1H3,(H,34,35) SJRVJRYZAQYCEE-UHFFFAOYSA-N 50212873 ((2'-(5-ETHYL-3,4-DIPHENYL-1H-PYRAZOL-1-YL)-3-BIPHENYLYL)OXY)ACETIC ACID::BMS309403::CHEMBL247920::[2'-(5-Ethyl-3,4-diphenyl-pyrazol-1-yl)-biphenyl-3-yloxy]-acetic acid Oxysterols receptor LXR-beta Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.2c01918 10.7270/Q2028WWR 37079895 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212873&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search T4B 4AZM,2NNQ 16122583 104088578 CHEMBL247920 6735 ZINC01549397 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564057 C[C@H]1CCCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C16H20N4O/c1-11-6-4-5-9-20(11)14-10-13(18-19-16(14)17)12-7-2-3-8-15(12)21/h2-3,7-8,10-11,21H,4-6,9H2,1H3,(H2,17,19)/t11-/m0/s1 KXXHZDPNIIOTSH-NSHDSACASA-N 394405 (S)-2-(6-amino-5-(2-::US10308614, Example 6 Oxysterols receptor LXR-beta Homo sapiens 300 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=394405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=394405&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137029398 405264503 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564058 Nc1nnc(cc1N1CCCCC1)-c1ccccc1O InChI=1S/C15H18N4O/c16-15-13(19-8-4-1-5-9-19)10-12(17-18-15)11-6-2-3-7-14(11)20/h2-3,6-7,10,20H,1,4-5,8-9H2,(H2,16,18) RJVQZTLPHCJXNB-UHFFFAOYSA-N 394490 2-(6-amino-5-(piperidin-1-yl)pyridazin-3-yl)phenol::US10308614, Example 90 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=394490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=394490&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137045907 405264585 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564059 Nc1nnc(cc1-c1ccccc1)-c1ccccc1O InChI=1S/C16H13N3O/c17-16-13(11-6-2-1-3-7-11)10-14(18-19-16)12-8-4-5-9-15(12)20/h1-10,20H,(H2,17,19) SDAWPVIWTVUTCC-UHFFFAOYSA-N 394583 2-(6-amino-5-phenylpyridazin-3-yl)phenol::US10308614, Example 186 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=394583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=394583&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search GGU 7TAB 137045897 405264677 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564060 C[C@@H]1CCCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C16H20N4O/c1-11-6-4-5-9-20(11)14-10-13(18-19-16(14)17)12-7-2-3-8-15(12)21/h2-3,7-8,10-11,21H,4-6,9H2,1H3,(H2,17,19)/t11-/m1/s1 KXXHZDPNIIOTSH-LLVKDONJSA-N 50628855 CHEMBL5411199 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628855&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564061 Nc1nnc(cc1N1CCCC1)-c1ccccc1O InChI=1S/C14H16N4O/c15-14-12(18-7-3-4-8-18)9-11(16-17-14)10-5-1-2-6-13(10)19/h1-2,5-6,9,19H,3-4,7-8H2,(H2,15,17) TWJZDPRYXHWSDF-UHFFFAOYSA-N 394434 2-(6-amino-5-(pyrrolidin-::US10308614, Example 35 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=394434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=394434&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137029371 405264532 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564062 C[C@H]1CCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C15H18N4O/c1-10-5-4-8-19(10)13-9-12(17-18-15(13)16)11-6-2-3-7-14(11)20/h2-3,6-7,9-10,20H,4-5,8H2,1H3,(H2,16,18)/t10-/m0/s1 CMJYPZQQLQOFCI-JTQLQIEISA-N 50628858 CHEMBL5401472 Oxysterols receptor LXR-beta Homo sapiens 6000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628858&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564063 C[C@@H]1CCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C15H18N4O/c1-10-5-4-8-19(10)13-9-12(17-18-15(13)16)11-6-2-3-7-14(11)20/h2-3,6-7,9-10,20H,4-5,8H2,1H3,(H2,16,18)/t10-/m1/s1 CMJYPZQQLQOFCI-SNVBAGLBSA-N 50628859 CHEMBL5425250 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628859&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564064 CC[C@H]1CCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C16H20N4O/c1-2-11-6-5-9-20(11)14-10-13(18-19-16(14)17)12-7-3-4-8-15(12)21/h3-4,7-8,10-11,21H,2,5-6,9H2,1H3,(H2,17,19)/t11-/m0/s1 AFMDWCUFHCSFCR-NSHDSACASA-N 50628860 CHEMBL5406315 Oxysterols receptor LXR-beta Homo sapiens 4200 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628860&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564065 Nc1nnc(cc1N1CCC[C@@H]1C1CC1)-c1ccccc1O InChI=1S/C17H20N4O/c18-17-15(21-9-3-5-14(21)11-7-8-11)10-13(19-20-17)12-4-1-2-6-16(12)22/h1-2,4,6,10-11,14,22H,3,5,7-9H2,(H2,18,20)/t14-/m1/s1 YRLBOSSSZSLHJB-CQSZACIVSA-N 50628861 CHEMBL5431862 Oxysterols receptor LXR-beta Homo sapiens 2100 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628861&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564066 C[C@H]1CCCCN1c1cc(nnc1N)-c1ccco1 InChI=1S/C14H18N4O/c1-10-5-2-3-7-18(10)12-9-11(16-17-14(12)15)13-6-4-8-19-13/h4,6,8-10H,2-3,5,7H2,1H3,(H2,15,17)/t10-/m0/s1 MUWVADGBLNVINA-JTQLQIEISA-N 50628869 CHEMBL5426305 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628869&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564067 Oc1ccccc1C(=O)\C=C\N1C[C@H]2C[C@@H]1CN2c1ccccn1 InChI=1S/C19H19N3O2/c23-17-6-2-1-5-16(17)18(24)8-10-21-12-15-11-14(21)13-22(15)19-7-3-4-9-20-19/h1-10,14-15,23H,11-13H2/b10-8+/t14-,15-/m1/s1 INAICWLVUAKEPB-QSTFCLMHSA-N 50158688 CHEMBL3752911 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158688&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5BW 5DKC,5DKD 78243717 340134359 CHEMBL3752911 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564068 C[C@@H]1CN(CCN1C(C)=O)c1cc(nnc1N)-c1ccccc1O InChI=1S/C17H21N5O2/c1-11-10-21(7-8-22(11)12(2)23)15-9-14(19-20-17(15)18)13-5-3-4-6-16(13)24/h3-6,9,11,24H,7-8,10H2,1-2H3,(H2,18,20)/t11-/m1/s1 FHRKRGDHMCCDEO-LLVKDONJSA-N 394530 (R)-1-(4-(3-amino-6-(2-::US10308614, Example 131 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=394530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=394530&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137029447 405264625 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564085 C[C@H]1CCCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C16H20N4O/c1-11-6-4-5-9-20(11)14-10-13(18-19-16(14)17)12-7-2-3-8-15(12)21/h2-3,7-8,10-11,21H,4-6,9H2,1H3,(H2,17,19)/t11-/m0/s1 KXXHZDPNIIOTSH-NSHDSACASA-N 394405 (S)-2-(6-amino-5-(2-::US10308614, Example 6 Oxysterols receptor LXR-beta Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=394405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=394405&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 137029398 405264503 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564086 C[C@H]1CCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C15H18N4O/c1-10-5-4-8-19(10)13-9-12(17-18-15(13)16)11-6-2-3-7-14(11)20/h2-3,6-7,9-10,20H,4-5,8H2,1H3,(H2,16,18)/t10-/m0/s1 CMJYPZQQLQOFCI-JTQLQIEISA-N 50628858 CHEMBL5401472 Oxysterols receptor LXR-beta Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628858&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564087 CC[C@H]1CCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C16H20N4O/c1-2-11-6-5-9-20(11)14-10-13(18-19-16(14)17)12-7-3-4-8-15(12)21/h3-4,7-8,10-11,21H,2,5-6,9H2,1H3,(H2,17,19)/t11-/m0/s1 AFMDWCUFHCSFCR-NSHDSACASA-N 50628860 CHEMBL5406315 Oxysterols receptor LXR-beta Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628860&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564088 Oc1ccccc1C(=O)\C=C\N1C[C@H]2C[C@@H]1CN2c1ccccn1 InChI=1S/C19H19N3O2/c23-17-6-2-1-5-16(17)18(24)8-10-21-12-15-11-14(21)13-22(15)19-7-3-4-9-20-19/h1-10,14-15,23H,11-13H2/b10-8+/t14-,15-/m1/s1 INAICWLVUAKEPB-QSTFCLMHSA-N 50158688 CHEMBL3752911 Oxysterols receptor LXR-beta Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158688&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 5BW 5DKC,5DKD 78243717 340134359 CHEMBL3752911 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564098 CC(C)[C@H]1CCCN1c1cc(nnc1N)-c1ccccc1O InChI=1S/C17H22N4O/c1-11(2)14-7-5-9-21(14)15-10-13(19-20-17(15)18)12-6-3-4-8-16(12)22/h3-4,6,8,10-11,14,22H,5,7,9H2,1-2H3,(H2,18,20)/t14-/m1/s1 FQZVWWGALUEODH-CQSZACIVSA-N 50628862 CHEMBL5409404 Oxysterols receptor LXR-beta Homo sapiens >20000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628862&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564099 C[C@H]1CCCN1c1cc(nnc1N)-c1ccco1 InChI=1S/C13H16N4O/c1-9-4-2-6-17(9)11-8-10(15-16-13(11)14)12-5-3-7-18-12/h3,5,7-9H,2,4,6H2,1H3,(H2,14,16)/t9-/m0/s1 HDGYSKKTWNREMX-VIFPVBQESA-N 50628863 CHEMBL5421138 Oxysterols receptor LXR-beta Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628863&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564100 C[C@H]1CCCCN1c1cc(nnc1N)-c1ccco1 InChI=1S/C14H18N4O/c1-10-5-2-3-7-18(10)12-9-11(16-17-14(12)15)13-6-4-8-19-13/h4,6,8-10H,2-3,5,7H2,1H3,(H2,15,17)/t10-/m0/s1 MUWVADGBLNVINA-JTQLQIEISA-N 50628869 CHEMBL5426305 Oxysterols receptor LXR-beta Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628869&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564101 C[C@@H]1CCCN1c1cc(nnc1N)-c1ccco1 InChI=1S/C13H16N4O/c1-9-4-2-6-17(9)11-8-10(15-16-13(11)14)12-5-3-7-18-12/h3,5,7-9H,2,4,6H2,1H3,(H2,14,16)/t9-/m1/s1 HDGYSKKTWNREMX-SECBINFHSA-N 50628872 CHEMBL5431005 Oxysterols receptor LXR-beta Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628872&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564102 CC[C@H]1CCCN1c1cc(nnc1N)-c1ccco1 InChI=1S/C14H18N4O/c1-2-10-5-3-7-18(10)12-9-11(16-17-14(12)15)13-6-4-8-19-13/h4,6,8-10H,2-3,5,7H2,1H3,(H2,15,17)/t10-/m0/s1 YSOVTDFGNDCQKR-JTQLQIEISA-N 50628873 CHEMBL5441040 Oxysterols receptor LXR-beta Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628873&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51564103 CC(C)[C@H]1CCCN1c1cc(nnc1N)-c1ccco1 InChI=1S/C15H20N4O/c1-10(2)12-5-3-7-19(12)13-9-11(17-18-15(13)16)14-6-4-8-20-14/h4,6,8-10,12H,3,5,7H2,1-2H3,(H2,16,18)/t12-/m1/s1 WCYMGNPKOMMLLN-GFCCVEGCSA-N 50628875 CHEMBL5415396 Oxysterols receptor LXR-beta Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.3c01149 10.7270/Q2ZP4BKG 37702400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50628875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50628875&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51566427 CC(C)=C[C@@H]1C[C@H]([C@H](O)O1)[C@@H]1CC[C@]2(C)C3=CC[C@H]4C(C)(C)C(=O)CC[C@]4(C)[C@H]3CC[C@@]12C InChI=1S/C30H46O3/c1-18(2)16-19-17-20(26(32)33-19)21-10-14-30(7)23-8-9-24-27(3,4)25(31)12-13-28(24,5)22(23)11-15-29(21,30)6/h8,16,19-22,24,26,32H,9-15,17H2,1-7H3/t19-,20+,21+,22+,24+,26-,28-,29+,30-/m1/s1 SLGYTUAMAYATHT-SETACZCPSA-N 50629933 CHEMBL5395293 Oxysterols receptor LXR-beta Homo sapiens 5300 ChEMBL 10.1021/acs.jnatprod.3c00059 10.7270/Q2H70M8Q 37526502 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629933&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51566428 CC(C)CC[C@@H](O)[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C InChI=1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25+,26-,27+/m0/s1 RZPAXNJLEKLXNO-GFKLAVDKSA-N 20177 (1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3R)-3-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::22(R)-hydroxycholesterol::CHEMBL422904 Oxysterols receptor LXR-beta Homo sapiens 1500 ChEMBL 10.1021/acs.jnatprod.3c00059 10.7270/Q2H70M8Q 37526502 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20177&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search HC9 3N9Z,3MZS,3L0J 167685 49688252 67237 CHEMBL422904 2742 C05502 ZINC04096816 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51531456 COC(=O)c1ccc(cc1S(C)(=O)=O)-c1cc(F)cc(c1)[C@H]1N(CC[C@]11C(=O)Nc2ccccc12)C(=O)OC(C)(C)C InChI=1S/C31H31FN2O7S/c1-30(2,3)41-29(37)34-13-12-31(23-8-6-7-9-24(23)33-28(31)36)26(34)20-14-19(15-21(32)16-20)18-10-11-22(27(35)40-4)25(17-18)42(5,38)39/h6-11,14-17,26H,12-13H2,1-5H3,(H,33,36)/t26-,31-/m1/s1 BLSQGQUYHGMBDP-MXBOTTGLSA-N 50616101 CHEMBL5431163 Oxysterols receptor LXR-beta Homo sapiens 300 ChEMBL 10.1021/acs.jmedchem.2c01661 10.7270/Q29G5S4F 36539349 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50616101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50616101&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 51531457 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta Homo sapiens 220 ChEMBL 10.1021/acs.jmedchem.2c01661 10.7270/Q29G5S4F 36539349 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=878&target=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE 4NQA,1UPW,1UPV,3KFC,1PQC,1PQ9,1PQ6,6S5K,6S4U,6S4T,6S4N,3L0E Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1