BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 156593 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor 0.69 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156594 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor 0.21 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156595 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor 1949.84 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156597 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor 0.05 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156598 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor 0.48 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156599 OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) JXTHEWSKYLZVJC-UHFFFAOYSA-N 81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594 D(2) dopamine receptor 7.07 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E7O 7QPC,7WKW,7Y9U 8594 131342351 60833 C06374 ZINC00028113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156600 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor 0.19 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156601 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor 5623.41 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156602 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor 204.17 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156603 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor 0.01 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 156604 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor 14.45 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157943 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor >10000 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157944 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor 0.9 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157945 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor 4.6 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157946 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor 1.3 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157947 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor 90 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157948 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor 0.34 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157949 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor 100 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157950 CN1CCN(CC1)C1=Nc2cc(F)ccc2Cc2ccccc12 InChI=1S/C19H20FN3/c1-22-8-10-23(11-9-22)19-17-5-3-2-4-14(17)12-15-6-7-16(20)13-18(15)21-19/h2-7,13H,8-12H2,1H3 OBWGMKKHCLHVIE-UHFFFAOYSA-N 50040241 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)::CHEMBL63756::Fluperlapine D(2) dopamine receptor 245 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49381 103972301 CHEMBL63756 279 C10967 ZINC26247473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157951 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor 0.84 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157952 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor 2.6 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157953 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor 7.6 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157954 CCCN1CCCC2Cc3[nH]ncc3CC12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15) FTSUPYGMFAPCFZ-UHFFFAOYSA-N 81873 CAS_55397::LY-171555::NSC_55397::QUINPIROLE D(2) dopamine receptor 720 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1257 131342447 ZINC08584336 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157955 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor 56 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157956 OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) JXTHEWSKYLZVJC-UHFFFAOYSA-N 81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594 D(2) dopamine receptor 4.1 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E7O 7QPC,7WKW,7Y9U 8594 131342351 60833 C06374 ZINC00028113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157957 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50028421 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax D(2) dopamine receptor 7.8 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103937709 8021 CHEMBL1275 DB01186 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157958 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor 4.8 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157959 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor 895 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157960 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor 9300 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157961 CN1CCc2cc(O)c(O)cc2C(C1)c1ccccc1 InChI=1S/C17H19NO2/c1-18-8-7-13-9-16(19)17(20)10-14(13)15(11-18)12-5-3-2-4-6-12/h2-6,9-10,15,19-20H,7-8,11H2,1H3 LIHCKGZEDBNUJG-UHFFFAOYSA-N 81986 3-Methyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride::CAS_173870::CHEMBL545000::NSC_173870::SKF 75670 D(2) dopamine receptor 840 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81986&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 173871 131342560 CHEMBL545000 936 ZINC04475345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157962 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor 0.11 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157963 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor 70 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157964 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor 1300 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157965 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor 34 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 157966 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Cc2sccc12 InChI=1S/C17H18ClN3S/c1-20-5-7-21(8-6-20)17-14-4-9-22-16(14)10-12-2-3-13(18)11-15(12)19-17/h2-4,9,11H,5-8,10H2,1H3 SKASXEDXLXEXKN-UHFFFAOYSA-N 81985 CAS_42239-60-1::NSC_172286::Tilozepine D(2) dopamine receptor 27 PDSP Ki 10.1016/0014-2999(88)90492-x 10.7270/Q21R6P1H 2895008 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81985&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172286 131342559 ZINC31490523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 173693 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor 65 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 173721 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor 1063 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 173724 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor 1473 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 336616 C(CN1CCO[C@H](COc2ccccc2)C1)N1CCc2ccccc12 InChI=1S/C21H26N2O2/c1-2-7-19(8-3-1)25-17-20-16-22(14-15-24-20)12-13-23-11-10-18-6-4-5-9-21(18)23/h1-9,20H,10-17H2/t20-/m0/s1 ZKTUDHGKQCWRDH-FQEVSTJZSA-N 186927 US9079895, 19s D(2) dopamine receptor 342 7.4 US Patent 10.7270/Q2D7996K aid1801769 US9079895 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K University of Dundee http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=186927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=186927&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71062646 315662714 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 336617 O=C(CN1CCO[C@H](COc2cccnc2)C1)N1CCc2ccccc12 InChI=1S/C20H23N3O3/c24-20(23-9-7-16-4-1-2-6-19(16)23)14-22-10-11-25-18(13-22)15-26-17-5-3-8-21-12-17/h1-6,8,12,18H,7,9-11,13-15H2/t18-/m0/s1 XYHRHHHLNLGIRG-SFHVURJKSA-N 186930 US9079895, 20s::US9079895, 21s D(2) dopamine receptor >10000 7.4 US Patent 10.7270/Q2D7996K aid1801769 US9079895 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K University of Dundee http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=186930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=186930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71062889 315662717 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 336618 Clc1cccc(OC[C@H]2CN(CCN3CCc4ccccc34)CCO2)c1 InChI=1S/C21H25ClN2O2/c22-18-5-3-6-19(14-18)26-16-20-15-23(12-13-25-20)10-11-24-9-8-17-4-1-2-7-21(17)24/h1-7,14,20H,8-13,15-16H2/t20-/m1/s1 QAJBOIGVHPCSNX-HXUWFJFHSA-N 186933 US9079895, 23r D(2) dopamine receptor >10000 7.4 US Patent 10.7270/Q2D7996K aid1801769 US9079895 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K University of Dundee http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=186933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=186933&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71061729 315662719 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 336619 Clc1cccc(OC[C@@H]2CN(CCN3CCc4ccccc34)CCO2)c1 InChI=1S/C21H25ClN2O2/c22-18-5-3-6-19(14-18)26-16-20-15-23(12-13-25-20)10-11-24-9-8-17-4-1-2-7-21(17)24/h1-7,14,20H,8-13,15-16H2/t20-/m0/s1 QAJBOIGVHPCSNX-FQEVSTJZSA-N 186935 US9079895, 23s D(2) dopamine receptor 1892 7.4 US Patent 10.7270/Q2D7996K aid1801769 US9079895 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K University of Dundee http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=186935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=186935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71061709 315662721 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 336620 COc1cccc(OC[C@@H]2CN(CCN3CCc4ccccc34)CCO2)c1 InChI=1S/C22H28N2O3/c1-25-19-6-4-7-20(15-19)27-17-21-16-23(13-14-26-21)11-12-24-10-9-18-5-2-3-8-22(18)24/h2-8,15,21H,9-14,16-17H2,1H3/t21-/m0/s1 ROKNCKQMECSPFV-NRFANRHFSA-N 186937 US9079895, 25s D(2) dopamine receptor 10000 7.4 US Patent 10.7270/Q2D7996K aid1801769 US9079895 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K University of Dundee http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=186937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=186937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71062708 315662723 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 336621 Clc1cncc(OC[C@@H]2CN(CCN3CCc4ccccc34)CCO2)c1 InChI=1S/C20H24ClN3O2/c21-17-11-18(13-22-12-17)26-15-19-14-23(9-10-25-19)7-8-24-6-5-16-3-1-2-4-20(16)24/h1-4,11-13,19H,5-10,14-15H2/t19-/m0/s1 QURJBQQAYVMKHZ-IBGZPJMESA-N 186942 US9079895, 27s D(2) dopamine receptor >10000 7.4 US Patent 10.7270/Q2D7996K aid1801769 US9079895 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K University of Dundee http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=186942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=186942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71086428 315662728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001919 Fc1ccc2[nH]cc(CC3CCN(CCN4c5cccc6cccc(NS4(=O)=O)c56)CC3)c2c1 InChI=1S/C26H27FN4O2S/c27-21-7-8-23-22(16-21)20(17-28-23)15-18-9-11-30(12-10-18)13-14-31-25-6-2-4-19-3-1-5-24(26(19)25)29-34(31,32)33/h1-8,16-18,28-29H,9-15H2 ZBMRQNIVMHCNOM-UHFFFAOYSA-N 50280818 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1H,3H-2-thia-1,3-diaza-phenalene 2,2-dioxide::CHEMBL60761 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300230 104122522 CHEMBL60761 ZINC29564490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001920 Fc1ccc2[nH]cc(CC3CCN(CCN4Cc5ccccc5S4(=O)=O)CC3)c2c1 InChI=1S/C23H26FN3O2S/c24-20-5-6-22-21(14-20)19(15-25-22)13-17-7-9-26(10-8-17)11-12-27-16-18-3-1-2-4-23(18)30(27,28)29/h1-6,14-15,17,25H,7-13,16H2 WABVGRGYPGCSGJ-UHFFFAOYSA-N 50280826 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-2,3-dihydro-benzo[d]isothiazole 1,1-dioxide::CHEMBL57483 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300238 104122530 CHEMBL57483 ZINC29560600 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001921 Fc1ccc2[nH]cc(CC3CCN(CCN4C(=O)C5(CC5)c5ccccc45)CC3)c2c1 InChI=1S/C26H28FN3O/c27-20-5-6-23-21(16-20)19(17-28-23)15-18-7-11-29(12-8-18)13-14-30-24-4-2-1-3-22(24)26(9-10-26)25(30)31/h1-6,16-18,28H,7-15H2 ZLKQAALBMPFYRJ-UHFFFAOYSA-N 50280827 1'-{2-[4-(5-fluoro-1H-3-indolylmethyl)hexahydro-1-pyridinyl]ethyl}spiro[cyclopropane-1,3'-(2',3'-dihydro-1'H-indole)]-2'-one::CHEMBL61256 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280827&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300182 104122531 CHEMBL61256 ZINC29563805 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001922 Fc1ccc2[nH]cc(CC3CCN(CCN4C(=O)Cc5ccccc45)CC3)c2c1 InChI=1S/C24H26FN3O/c25-20-5-6-22-21(15-20)19(16-26-22)13-17-7-9-27(10-8-17)11-12-28-23-4-2-1-3-18(23)14-24(28)29/h1-6,15-17,26H,7-14H2 HCCDMOJGYYKKLX-UHFFFAOYSA-N 50280824 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1,3-dihydro-indol-2-one::CHEMBL300786 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300239 104122528 CHEMBL300786 ZINC29563408 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001923 COc1nc2cccc3cccc(n1CCN1CCC(Cc4c[nH]c5ccc(F)cc45)CC1)c23 InChI=1S/C28H29FN4O/c1-34-28-31-25-6-2-4-20-5-3-7-26(27(20)25)33(28)15-14-32-12-10-19(11-13-32)16-21-18-30-24-9-8-22(29)17-23(21)24/h2-9,17-19,30H,10-16H2,1H3 MVTFHDOBFMXGDB-UHFFFAOYSA-N 50280820 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-2-methoxy-1H-perimidine::CHEMBL418276 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300243 104122524 CHEMBL418276 ZINC29559797 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001924 C[Si]1(C)CN(CCN2CCC(Cc3c[nH]c4ccc(F)cc34)CC2)C(=O)c2ccccc12 InChI=1S/C26H32FN3OSi/c1-32(2)18-30(26(31)22-5-3-4-6-25(22)32)14-13-29-11-9-19(10-12-29)15-20-17-28-24-8-7-21(27)16-23(20)24/h3-8,16-17,19,28H,9-15,18H2,1-2H3 FLDCEHWXDRNEEH-UHFFFAOYSA-N 50280828 3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1,1-dimethyl-2,3-dihydro-1H-benzo[d][1,3]azasilin-4-one::CHEMBL56571 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300167 104122532 CHEMBL56571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001925 Fc1ccc2[nH]cc(CC3CCN(CCN4C(=O)CSc5ccccc45)CC3)c2c1 InChI=1S/C24H26FN3OS/c25-19-5-6-21-20(14-19)18(15-26-21)13-17-7-9-27(10-8-17)11-12-28-22-3-1-2-4-23(22)30-16-24(28)29/h1-6,14-15,17,26H,7-13,16H2 JSPVAYAOSGJUAY-UHFFFAOYSA-N 50280822 4-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-4H-benzo[1,4]thiazin-3-one::CHEMBL294425 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300228 104122526 CHEMBL294425 ZINC29560061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001926 CC1(C)CN(CCN2CCC(Cc3c[nH]c4ccc(F)cc34)CC2)C(=O)c2ccccc12 InChI=1S/C27H32FN3O/c1-27(2)18-31(26(32)22-5-3-4-6-24(22)27)14-13-30-11-9-19(10-12-30)15-20-17-29-25-8-7-21(28)16-23(20)25/h3-8,16-17,19,29H,9-15,18H2,1-2H3 ICSRAOOGQDHJBO-UHFFFAOYSA-N 50280832 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-4,4-dimethyl-3,4-dihydro-2H-isoquinolin-1-one::CHEMBL417785 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300171 104122536 CHEMBL417785 ZINC29560873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001927 CN1c2cccc3cccc(N(CCN4CCC(Cc5c[nH]c6ccc(F)cc56)CC4)S1(=O)=O)c23 InChI=1S/C27H29FN4O2S/c1-30-25-6-2-4-20-5-3-7-26(27(20)25)32(35(30,33)34)15-14-31-12-10-19(11-13-31)16-21-18-29-24-9-8-22(28)17-23(21)24/h2-9,17-19,29H,10-16H2,1H3 LEIJMDSSQGAVTK-UHFFFAOYSA-N 50280823 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-3-methyl-1H,3H-2-thia-1,3-diaza-phenalene 2,2-dioxide::CHEMBL61149 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300232 104122527 CHEMBL61149 ZINC29563185 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001928 C[Si]1(C)CN(CCN2CCC(Cc3c[nH]c4ccc(F)cc34)CC2)S(=O)(=O)c2ccccc12 InChI=1S/C25H32FN3O2SSi/c1-33(2)18-29(32(30,31)24-5-3-4-6-25(24)33)14-13-28-11-9-19(10-12-28)15-20-17-27-23-8-7-21(26)16-22(20)23/h3-8,16-17,19,27H,9-15,18H2,1-2H3 BMKAEZCWYDIUCE-UHFFFAOYSA-N 50280821 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-4,4-dimethyl-3,4-dihydro-2H-benzo[1,2,4]thiazasiline 1,1-dioxide::CHEMBL57514 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300172 104122525 CHEMBL57514 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001929 Fc1ccc2[nH]cc(CC3CCN(CCn4c5cccc6cccc([nH]c4=O)c56)CC3)c2c1 InChI=1S/C27H27FN4O/c28-21-7-8-23-22(16-21)20(17-29-23)15-18-9-11-31(12-10-18)13-14-32-25-6-2-4-19-3-1-5-24(26(19)25)30-27(32)33/h1-8,16-18,29H,9-15H2,(H,30,33) QHPHOWVDZTXSOR-UHFFFAOYSA-N 50280819 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1H,3H-perimidin-2-one::CHEMBL57506 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300240 104122523 CHEMBL57506 ZINC29562138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001930 CN(CCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1)S(=O)(=O)c1ccccc1 InChI=1S/C23H28FN3O2S/c1-26(30(28,29)21-5-3-2-4-6-21)13-14-27-11-9-18(10-12-27)15-19-17-25-23-8-7-20(24)16-22(19)23/h2-8,16-18,25H,9-15H2,1H3 VWWJOACRVWQPPL-UHFFFAOYSA-N 50280816 CHEMBL293729::N-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-N-methyl-benzenesulfonamide D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300131 104122520 CHEMBL293729 ZINC29564666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001931 Fc1ccc2[nH]cc(CC3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3)c2c1 InChI=1S/C28H26FN3O2/c29-21-7-8-25-24(16-21)20(17-30-25)15-18-9-11-31(12-10-18)13-14-32-27(33)22-5-1-3-19-4-2-6-23(26(19)22)28(32)34/h1-8,16-18,30H,9-15H2 LTAMYBBMBMWTMB-UHFFFAOYSA-N 50280831 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-benzo[de]isoquinoline-1,3-dione::CHEMBL60640 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300224 104122535 CHEMBL60640 ZINC29562407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001932 Cn1c(=O)n(CCN2CCC(Cc3c[nH]c4ccc(F)cc34)CC2)c2ccccc2c1=O InChI=1S/C25H27FN4O2/c1-28-24(31)20-4-2-3-5-23(20)30(25(28)32)13-12-29-10-8-17(9-11-29)14-18-16-27-22-7-6-19(26)15-21(18)22/h2-7,15-17,27H,8-14H2,1H3 PJJYCJPLKPIMIR-UHFFFAOYSA-N 50280825 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-3-methyl-1H-quinazoline-2,4-dione::CHEMBL57047 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300229 104122529 CHEMBL57047 ZINC29560063 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001933 Fc1ccc2[nH]cc(CC3CCN(CCn4c(=O)[nH]c5ccccc5c4=O)CC3)c2c1 InChI=1S/C24H25FN4O2/c25-18-5-6-21-20(14-18)17(15-26-21)13-16-7-9-28(10-8-16)11-12-29-23(30)19-3-1-2-4-22(19)27-24(29)31/h1-6,14-16,26H,7-13H2,(H,27,31) OIYZVNIQJKHCEA-UHFFFAOYSA-N 50280830 3-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1H-quinazoline-2,4-dione::CHEMBL300585 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280830&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299849 104122534 CHEMBL300585 ZINC29563967 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001934 OC1=CN(CCN2CCC(Cc3c[nH]c4ccc(F)cc34)CC2)S(=O)(=O)c2ccccc12 InChI=1S/C24H26FN3O3S/c25-19-5-6-22-21(14-19)18(15-26-22)13-17-7-9-27(10-8-17)11-12-28-16-23(29)20-3-1-2-4-24(20)32(28,30)31/h1-6,14-17,26,29H,7-13H2 YELYMKQLVXIVMT-UHFFFAOYSA-N 50280829 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-benzo[e][1,2]thiazin-4-one::CHEMBL57198 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280829&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91934687 104122533 CHEMBL57198 ZINC29557069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001935 Fc1ccc2[nH]cc(CC3CCN(CCNS(=O)(=O)c4ccccc4)CC3)c2c1 InChI=1S/C22H26FN3O2S/c23-19-6-7-22-21(15-19)18(16-24-22)14-17-8-11-26(12-9-17)13-10-25-29(27,28)20-4-2-1-3-5-20/h1-7,15-17,24-25H,8-14H2 YEGWUPOWDGANIN-UHFFFAOYSA-N 50280815 CHEMBL56377::N-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-benzenesulfonamide D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300196 104122519 CHEMBL56377 ZINC29560723 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50001936 Fc1ccc2[nH]cc(CC3CCN(CCN4C(=O)Nc5ccccc5S4(=O)=O)CC3)c2c1 InChI=1S/C23H25FN4O3S/c24-18-5-6-20-19(14-18)17(15-25-20)13-16-7-9-27(10-8-16)11-12-28-23(29)26-21-3-1-2-4-22(21)32(28,30)31/h1-6,14-16,25H,7-13H2,(H,26,29) LUBDXUGRYJBFRI-UHFFFAOYSA-N 50280817 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1,1-dioxo-1,4-dihydro-2H-1lambda*6*-benzo[1,2,4]thiadiazin-3-one::CHEMBL299917 D(2) dopamine receptor >100 ChEMBL 10.1016/S0960-894X(01)80986-0 10.7270/Q27944M4 Mignani, S; Damour, D; Doble, A; Labaudinière, R; Malleron, JL; Piot, O; Gueremy, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299828 104122521 CHEMBL299917 ZINC29552720 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50009605 CCS(=O)(=O)Nc1cccc(c1)N1CCN(CCCCn2c(O)c3CCCn3c2=O)CC1 InChI=1S/C22H33N5O4S/c1-2-32(30,31)23-18-7-5-8-19(17-18)25-15-13-24(14-16-25)10-3-4-11-27-21(28)20-9-6-12-26(20)22(27)29/h5,7-8,17,23,28H,2-4,6,9-16H2,1H3 OHRUJLACQQIEJZ-UHFFFAOYSA-N 50078561 CHEMBL1204203::CHEMBL416266::Ethanesulfonic acid (3-{4-[4-(1,3-dioxo-tetrahydro-pyrrolo[1,2-c]imidazol-2-yl)-butyl]-piperazin-1-yl}-phenyl)-amide::Ethanesulfonic acid (3-{4-[4-(1,3-dioxo-tetrahydro-pyrrolo[1,2-c]imidazol-2-yl)-butyl]-piperazin-1-yl}-phenyl)-amide (EF-7412) D(2) dopamine receptor 22 ChEMBL 10.1016/s0960-894x(99)00254-1 10.7270/Q2R210JP 10397500 Lopez-Rodriguez, ML; Morcillo, MJ; Fernandez, E; Rosado, ML; Orensanz, L; Beneytez, ME; Manzanares, J; Fuentes, JA; Schaper, KJ Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54150941 103971107 CHEMBL1204203CHEMBL416266 ZINC49799784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50023999 CC[S+]1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H22N2O4S2/c1-3-22-8-4-5-11(22)10-17-15(18)13-9-12(23(16,19)20)6-7-14(13)21-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H2-,16,17,18,19,20)/p+1 MMVRJSFVMXZCEG-UHFFFAOYSA-O 50016778 1-Ethyl-2-[(2-methoxy-5-sulfamoyl-benzoylamino)-methyl]-tetrahydro-thiophenium; iodide::CHEMBL170622 D(2) dopamine receptor 5.2 ChEMBL 10.1021/jm00124a024 10.7270/Q23B5Z48 2522993 Harrold, MW; Wallace, RA; Farooqui, T; Wallace, LJ; Uretsky, N; Miller, DD Ohio State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44382264 103928147 CHEMBL170622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044160 Nc1cnccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H26N6OS/c22-18-15-23-9-7-16(18)21(28)24-8-3-4-10-26-11-13-27(14-12-26)20-17-5-1-2-6-19(17)29-25-20/h1-2,5-7,9,15H,3-4,8,10-14,22H2,(H,24,28) JQKRQKUNQKFRTP-UHFFFAOYSA-N 50054717 3-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-isonicotinamide::CHEMBL143447 D(2) dopamine receptor 16 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054717&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10597700 103951302 CHEMBL143447 ZINC13760425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044161 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor 290 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044164 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2nc[nH]c12 InChI=1S/C23H26N6OS/c30-23(18-7-5-8-19-21(18)26-16-25-19)24-10-3-4-11-28-12-14-29(15-13-28)22-17-6-1-2-9-20(17)31-27-22/h1-2,5-9,16H,3-4,10-15H2,(H,24,30)(H,25,26) VFYDENPYYCCZII-UHFFFAOYSA-N 50054712 3H-Benzoimidazole-4-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL141319 D(2) dopamine receptor 7.6 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646494 103951297 CHEMBL141319 ZINC13760430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044166 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor 23 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044172 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2CCCNc12 InChI=1S/C25H31N5OS/c31-25(21-10-5-7-19-8-6-13-26-23(19)21)27-12-3-4-14-29-15-17-30(18-16-29)24-20-9-1-2-11-22(20)32-28-24/h1-2,5,7,9-11,26H,3-4,6,8,12-18H2,(H,27,31) RPBVWEILTAVEHF-UHFFFAOYSA-N 50054710 1,2,3,4-Tetrahydro-quinoline-8-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL356743 D(2) dopamine receptor 28 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054710&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10694821 103951295 CHEMBL356743 ZINC13760429 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044179 Nc1ncccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H26N6OS/c22-19-17(7-5-10-23-19)21(28)24-9-3-4-11-26-12-14-27(15-13-26)20-16-6-1-2-8-18(16)29-25-20/h1-2,5-8,10H,3-4,9,11-15H2,(H2,22,23)(H,24,28) VXSBWAZGDNTUOU-UHFFFAOYSA-N 50054705 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-nicotinamide::CHEMBL141392 D(2) dopamine receptor 7.8 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054705&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716504 103951290 CHEMBL141392 ZINC13760426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044180 Nc1sccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C20H25N5OS2/c21-18-16(7-14-27-18)20(26)22-8-3-4-9-24-10-12-25(13-11-24)19-15-5-1-2-6-17(15)28-23-19/h1-2,5-7,14H,3-4,8-13,21H2,(H,22,26) XJOFOTULUMAAAE-UHFFFAOYSA-N 50054713 2-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL141485 D(2) dopamine receptor 11 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054713&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10597962 103951298 CHEMBL141485 ZINC27525008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044181 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1ccccn1 InChI=1S/C21H25N5OS/c27-21(18-8-3-4-10-22-18)23-11-5-6-12-25-13-15-26(16-14-25)20-17-7-1-2-9-19(17)28-24-20/h1-4,7-10H,5-6,11-16H2,(H,23,27) UEVPZHOMMNFGGS-UHFFFAOYSA-N 50054707 CHEMBL344994::Pyridine-2-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide D(2) dopamine receptor 24 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054707&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572792 103951292 CHEMBL344994 ZINC01539372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044182 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2cc[nH]c12 InChI=1S/C24H27N5OS/c30-24(20-8-5-6-18-10-12-25-22(18)20)26-11-3-4-13-28-14-16-29(17-15-28)23-19-7-1-2-9-21(19)31-27-23/h1-2,5-10,12,25H,3-4,11,13-17H2,(H,26,30) WPFSGXCJMOESPT-UHFFFAOYSA-N 50054706 1H-Indole-7-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL343228 D(2) dopamine receptor 28 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054706&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797049 103951291 CHEMBL343228 ZINC13760431 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044184 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1c[nH]c2ccccc12 InChI=1S/C24H27N5OS/c30-24(20-17-26-21-9-3-1-7-18(20)21)25-11-5-6-12-28-13-15-29(16-14-28)23-19-8-2-4-10-22(19)31-27-23/h1-4,7-10,17,26H,5-6,11-16H2,(H,25,30) NTTCFOLAAJRIDE-UHFFFAOYSA-N 50054708 1H-Indole-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL142456 D(2) dopamine receptor 14 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054708&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717656 103951293 CHEMBL142456 ZINC12356422 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044186 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2cccnc12 InChI=1S/C25H27N5OS/c31-25(21-10-5-7-19-8-6-13-26-23(19)21)27-12-3-4-14-29-15-17-30(18-16-29)24-20-9-1-2-11-22(20)32-28-24/h1-2,5-11,13H,3-4,12,14-18H2,(H,27,31) RKPLYODDRKZPRV-UHFFFAOYSA-N 50054703 CHEMBL358268::Quinoline-8-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide D(2) dopamine receptor 14 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054703&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575339 103951288 CHEMBL358268 ZINC12356447 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044187 Nc1c(sc2ccccc12)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H27N5OS2/c25-21-17-7-1-3-9-19(17)31-22(21)24(30)26-11-5-6-12-28-13-15-29(16-14-28)23-18-8-2-4-10-20(18)32-27-23/h1-4,7-10H,5-6,11-16,25H2,(H,26,30) XZSJDMCGNCINRX-UHFFFAOYSA-N 50054702 3-Amino-benzo[b]thiophene-2-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL142850 D(2) dopamine receptor 5.8 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054702&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10576148 103951287 CHEMBL142850 ZINC13760428 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044188 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1[nH]nc2ccccc12 InChI=1S/C23H26N6OS/c30-23(21-17-7-1-3-9-19(17)25-26-21)24-11-5-6-12-28-13-15-29(16-14-28)22-18-8-2-4-10-20(18)31-27-22/h1-4,7-10H,5-6,11-16H2,(H,24,30)(H,25,26) FHVURUHIMBFDDS-UHFFFAOYSA-N 50054716 1H-Indazole-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL343838 D(2) dopamine receptor 2.2 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836602 103951301 CHEMBL343838 ZINC13760432 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044189 Nc1ccsc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C20H25N5OS2/c21-16-7-14-27-18(16)20(26)22-8-3-4-9-24-10-12-25(13-11-24)19-15-5-1-2-6-17(15)28-23-19/h1-2,5-7,14H,3-4,8-13,21H2,(H,22,26) MKGAPJXMHJSSQN-UHFFFAOYSA-N 50054718 3-Amino-thiophene-2-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL141438 D(2) dopamine receptor 9.6 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054718&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10341805 103951303 CHEMBL141438 ZINC01539371 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044190 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccc2CCNc12 InChI=1S/C24H29N5OS/c30-24(20-8-5-6-18-10-12-25-22(18)20)26-11-3-4-13-28-14-16-29(17-15-28)23-19-7-1-2-9-21(19)31-27-23/h1-2,5-9,25H,3-4,10-17H2,(H,26,30) VIHHTBYBRANJQC-UHFFFAOYSA-N 50054704 2,3-Dihydro-1H-indole-7-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL142277 D(2) dopamine receptor 34 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054704&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797166 103951289 CHEMBL142277 ZINC12356413 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044191 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1cccnc1 InChI=1S/C21H25N5OS/c27-21(17-6-5-9-22-16-17)23-10-3-4-11-25-12-14-26(15-13-25)20-18-7-1-2-8-19(18)28-24-20/h1-2,5-9,16H,3-4,10-15H2,(H,23,27) XSEKCANDBURYRF-UHFFFAOYSA-N 50054719 CHEMBL356498::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-nicotinamide D(2) dopamine receptor 47 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054719&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10500912 103951304 CHEMBL356498 ZINC01539373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044192 Nc1cscc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C20H25N5OS2/c21-17-14-27-13-16(17)20(26)22-7-3-4-8-24-9-11-25(12-10-24)19-15-5-1-2-6-18(15)28-23-19/h1-2,5-6,13-14H,3-4,7-12,21H2,(H,22,26) ANZGKDRXGOPIJA-UHFFFAOYSA-N 50054715 4-Amino-thiophene-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL143075 D(2) dopamine receptor 6 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054715&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669552 103951300 CHEMBL143075 ZINC13760427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044193 Nc1cccnc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H26N6OS/c22-17-7-5-10-23-19(17)21(28)24-9-3-4-11-26-12-14-27(15-13-26)20-16-6-1-2-8-18(16)29-25-20/h1-2,5-8,10H,3-4,9,11-15,22H2,(H,24,28) HRDPYIFRAIOXAE-UHFFFAOYSA-N 50054714 3-Amino-pyridine-2-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL142211 D(2) dopamine receptor 24 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054714&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9844458 103951299 CHEMBL142211 ZINC01539370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044194 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1ccncc1 InChI=1S/C21H25N5OS/c27-21(17-7-10-22-11-8-17)23-9-3-4-12-25-13-15-26(16-14-25)20-18-5-1-2-6-19(18)28-24-20/h1-2,5-8,10-11H,3-4,9,12-16H2,(H,23,27) LEBIUZBOHXBTBZ-UHFFFAOYSA-N 50054709 CHEMBL141494::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-isonicotinamide D(2) dopamine receptor 25 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054709&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620723 103951294 CHEMBL141494 ZINC13760423 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50044197 Nc1ccncc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H26N6OS/c22-18-7-9-23-15-17(18)21(28)24-8-3-4-10-26-11-13-27(14-12-26)20-16-5-1-2-6-19(16)29-25-20/h1-2,5-7,9,15H,3-4,8,10-14H2,(H2,22,23)(H,24,28) XFUBOVYBCDSIHJ-UHFFFAOYSA-N 50054711 4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-nicotinamide::CHEMBL342742 D(2) dopamine receptor 4.7 ChEMBL 10.1021/jm9603375 10.7270/Q2VT1R6T 8941382 Norman, MH; Navas, F; Thompson, JB; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054711&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795852 103951296 CHEMBL342742 ZINC13760424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50175313 NCC1c2ccccc2Cc2ccccc12 InChI=1S/C15H15N/c16-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)15/h1-8,15H,9-10,16H2 GEICAQNIOJFRQN-UHFFFAOYSA-N 35920 9,10-dihydroanthracene(DHA), 1a::9-(Aminomethyl)-9,10-dihydroanthracene::9-aminomethyl-9,10-dihydroanthracene::C-(9,10-Dihydro-anthracen-9-yl)-methylamine::CHEMBL47482 D(2) dopamine receptor >10000 ChEMBL 10.1016/s0960-894x(01)00023-3 10.7270/Q2H994F8 11266163 Runyon, SP; Savage, JE; Taroua, M; Roth, BL; Glennon, RA; Westkaemper, RB Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10398175 85856713 CHEMBL47482 ZINC13473096 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50175316 CN(C)CCCN1c2ccccc2CCc2ccccc12 InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 BCGWQEUPMDMJNV-UHFFFAOYSA-N 50010859 CHEMBL11::IMIPRAMINE HYDROCHLORIDE::IMIPRAMINE PAMOATE::Imipramin D(2) dopamine receptor 726 ChEMBL 10.1016/s0960-894x(01)00023-3 10.7270/Q2H994F8 11266163 Runyon, SP; Savage, JE; Taroua, M; Roth, BL; Glennon, RA; Westkaemper, RB Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search IXX 2Q72,7LWD,6G9B 3696 103923605 47499 CHEMBL11 DB00458 357 C07049 ZINC00020245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50175335 CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12 InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3 JJCFRYNCJDLXIK-UHFFFAOYSA-N 50017721 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine::1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine::4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine::4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine::4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine::5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene::CHEMBL516::CYPROHEPTADINE D(2) dopamine receptor 112 ChEMBL 10.1016/s0960-894x(01)00023-3 10.7270/Q2H994F8 11266163 Runyon, SP; Savage, JE; Taroua, M; Roth, BL; Glennon, RA; Westkaemper, RB Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search C7H 5AYF 2913 103928989 4046 CHEMBL516 DB00434 277 C06935 ZINC00968264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50730422 CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1Br InChI=1S/C17H17BrClNO/c1-20-7-6-11-8-16(19)17(21)9-13(11)14(10-20)12-4-2-3-5-15(12)18/h2-5,8-9,14,21H,6-7,10H2,1H3 YFZYRKUTAITPML-UHFFFAOYSA-N 50088755 5-(2-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL13325::SCH-23390 D(2) dopamine receptor 583 ChEMBL 10.1016/s0960-894x(00)00185-2 10.7270/Q21N81NF 10843230 Tamagnan, G; Baldwin, RM; Kula, NS; Baldessarini, RJ; Innis, RB Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268693 103987630 CHEMBL13325 ZINC36238007 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50730426 CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(Br)c1 InChI=1S/C17H17BrClNO/c1-20-6-5-12-8-16(19)17(21)9-14(12)15(10-20)11-3-2-4-13(18)7-11/h2-4,7-9,15,21H,5-6,10H2,1H3 AJFLQDIECOEENG-UHFFFAOYSA-N 50088753 5-(3-Bromo-phenyl)-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL13632::SCH-23390 D(2) dopamine receptor 1120 ChEMBL 10.1016/s0960-894x(00)00185-2 10.7270/Q21N81NF 10843230 Tamagnan, G; Baldwin, RM; Kula, NS; Baldessarini, RJ; Innis, RB Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14896355 103987628 CHEMBL13632 ZINC36238010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50730429 CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(c1)C(=O)C1=CC=C[C@@H]1[Re](C=O)(C=O)C=O InChI=1S/C23H21ClNO2.3CHO.Re/c1-25-10-9-17-12-21(24)22(26)13-19(17)20(14-25)16-7-4-8-18(11-16)23(27)15-5-2-3-6-15;3*1-2;/h2-8,11-13,20,26H,9-10,14H2,1H3;3*1H; IPCUQJQVMYKRGI-UHFFFAOYSA-N 50088756 CHEMBL427996::Cyclopentadienyltricarbonylrheniumbenzazepine (3`-CPTR-SCH-23390) D(2) dopamine receptor >10000 ChEMBL 10.1016/s0960-894x(00)00185-2 10.7270/Q21N81NF 10843230 Tamagnan, G; Baldwin, RM; Kula, NS; Baldessarini, RJ; Innis, RB Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268688 103987631 CHEMBL427996 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50730433 CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1C(=O)C1=CC=C[C@@H]1[Re](C=O)(C=O)C=O InChI=1S/C23H21ClNO2.3CHO.Re/c1-25-11-10-16-12-21(24)22(26)13-19(16)20(14-25)17-8-4-5-9-18(17)23(27)15-6-2-3-7-15;3*1-2;/h2-9,12-13,20,26H,10-11,14H2,1H3;3*1H; MTETXAOPUKRGDV-UHFFFAOYSA-N 50088754 CHEMBL274577::Cyclopentadienyltricarbonylrheniumbenzazepine (2`-CPTR-SCH-23390) D(2) dopamine receptor 549 ChEMBL 10.1016/s0960-894x(00)00185-2 10.7270/Q21N81NF 10843230 Tamagnan, G; Baldwin, RM; Kula, NS; Baldessarini, RJ; Innis, RB Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088754&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268809 103987629 CHEMBL274577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50730437 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor 1210 ChEMBL 10.1016/s0960-894x(00)00185-2 10.7270/Q21N81NF 10843230 Tamagnan, G; Baldwin, RM; Kula, NS; Baldessarini, RJ; Innis, RB Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761697 COc1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H25NO2/c1-24-20-9-7-19(8-10-20)21(23)15-17-11-13-22(14-12-17)16-18-5-3-2-4-6-18/h2-10,17H,11-16H2,1H3 JJCZVGWEJHEXPS-UHFFFAOYSA-N 50002189 2-(1-Benzyl-piperidin-4-yl)-1-(4-methoxy-phenyl)-ethanone::CHEMBL134578 D(2) dopamine receptor 6070 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002189&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10087571 103916495 CHEMBL134578 ZINC13729892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761699 CN(C)c1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C19H28N2O/c1-20(2)18-7-5-17(6-8-18)19(22)13-15-9-11-21(12-10-15)14-16-3-4-16/h5-8,15-16H,3-4,9-14H2,1-2H3 GBIJZZWGZZVKLW-UHFFFAOYSA-N 50002193 2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-dimethylamino-phenyl)-ethanone; DIhydrobromide;0.5hydrate::CHEMBL543206 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10434462 103916499 CHEMBL543206 ZINC13729924 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761700 Fc1ccc(COCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C20H24FNO/c21-20-8-6-18(7-9-20)15-23-16-19-10-12-22(13-11-19)14-17-4-2-1-3-5-17/h1-9,19H,10-16H2 XBBPMZNIRPSONU-UHFFFAOYSA-N 50002190 1-Benzyl-4-(4-fluoro-benzyloxymethyl)-piperidine; compound with but-2-enedioic acid::CHEMBL136495 D(2) dopamine receptor 3900 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10358222 103916496 CHEMBL136495 ZINC13730105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761705 Fc1ccc(CC(=O)CC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C21H24FNO/c22-20-8-6-17(7-9-20)14-21(24)15-18-10-12-23(13-11-18)16-19-4-2-1-3-5-19/h1-9,18H,10-16H2 FYPKCXCUYFTOMN-UHFFFAOYSA-N 50002197 1-(1-Benzyl-piperidin-4-yl)-3-(4-fluoro-phenyl)-propan-2-one; compound with but-2-enedioic acid::CHEMBL334466 D(2) dopamine receptor 1100 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10048935 103916503 CHEMBL334466 ZINC13730006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761709 C(OCc1ccc(cc1)-c1ccccc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C26H29NO/c1-3-7-22(8-4-1)19-27-17-15-24(16-18-27)21-28-20-23-11-13-26(14-12-23)25-9-5-2-6-10-25/h1-14,24H,15-21H2 IXUZKLIPOQFKNW-UHFFFAOYSA-N 50002204 1-Benzyl-4-(biphenyl-4-ylmethoxymethyl)-piperidine; compound with but-2-enedioic acid;0.5hydrate::CHEMBL137658 D(2) dopamine receptor 1850 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002204&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361876 103916510 CHEMBL137658 ZINC13730111 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761710 COc1ccc(cc1)C(O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H27NO2/c1-24-20-9-7-19(8-10-20)21(23)15-17-11-13-22(14-12-17)16-18-5-3-2-4-6-18/h2-10,17,21,23H,11-16H2,1H3 VQGUXXCQJVXIGH-UHFFFAOYSA-N 50002203 2-(1-Benzyl-piperidin-4-yl)-1-(4-methoxy-phenyl)-ethanol; hydrochloride::CHEMBL539042 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002203&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10090008 103916509 CHEMBL539042 ZINC13729969 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761712 COc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C17H25NO2/c1-19-16-4-6-17(7-5-16)20-13-15-8-10-18(11-9-15)12-14-2-3-14/h4-7,14-15H,2-3,8-13H2,1H3 LHKCQPVEKOZEPP-UHFFFAOYSA-N 50002208 1-Cyclopropylmethyl-4-(4-methoxy-phenoxymethyl)-piperidine; hydrochloride;0.25hydrate::CHEMBL555993 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002208&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10358126 103916514 CHEMBL555993 ZINC13730013 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761716 Fc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C16H22FNO/c17-15-3-5-16(6-4-15)19-12-14-7-9-18(10-8-14)11-13-1-2-13/h3-6,13-14H,1-2,7-12H2 GXKBHNBKDZPNIG-UHFFFAOYSA-N 50002207 1-Cyclopropylmethyl-4-(4-fluoro-phenoxymethyl)-piperidine::CHEMBL335327 D(2) dopamine receptor 381 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002207&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015631 103916513 CHEMBL335327 ZINC00013938 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761721 CC1CC1CN1CCC(COc2ccc(F)cc2)CC1 InChI=1S/C17H24FNO/c1-13-10-15(13)11-19-8-6-14(7-9-19)12-20-17-4-2-16(18)3-5-17/h2-5,13-15H,6-12H2,1H3 OJWSYROOSOOKHZ-UHFFFAOYSA-N 50002200 4-(4-Fluoro-phenoxymethyl)-1-(2-methyl-cyclopropylmethyl)-piperidine; compound with but-2-enedioic acid::CHEMBL137085 D(2) dopamine receptor 945 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002200&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10000659 103916506 CHEMBL137085 ZINC13730087 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761722 Fc1ccc(cc1)S(=O)(=O)CC1CCN(CCC2CC2)CC1 InChI=1S/C17H24FNO2S/c18-16-3-5-17(6-4-16)22(20,21)13-15-8-11-19(12-9-15)10-7-14-1-2-14/h3-6,14-15H,1-2,7-13H2 NEVJGJJRNMUIDT-UHFFFAOYSA-N 50002210 1-(2-Cyclopropyl-ethyl)-4-(4-fluoro-benzenesulfonylmethyl)-piperidine::CHEMBL137339 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002210&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15147198 103916516 CHEMBL137339 ZINC27439949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761723 Fc1ccc(cc1)-c1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C22H26FNO/c23-21-7-3-19(4-8-21)20-5-9-22(10-6-20)25-16-18-11-13-24(14-12-18)15-17-1-2-17/h3-10,17-18H,1-2,11-16H2 NSAGPFMSGUVVAX-UHFFFAOYSA-N 50002211 1-Cyclopropylmethyl-4-(4'-fluoro-biphenyl-4-yloxymethyl)-piperidine::CHEMBL138992 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002211&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10359843 103916517 CHEMBL138992 ZINC13730057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761727 CS(=O)c1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H25NO2S/c1-25(24)20-9-7-19(8-10-20)21(23)15-17-11-13-22(14-12-17)16-18-5-3-2-4-6-18/h2-10,17H,11-16H2,1H3 FDANJYRCEXIYKH-UHFFFAOYSA-N 50002214 2-(1-Benzyl-piperidin-4-yl)-1-(4-methanesulfinyl-phenyl)-ethanone;0.25hydrate::CHEMBL337148 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002214&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021122 103916520 CHEMBL337148 ZINC13729912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761728 Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccccc2)CC1 InChI=1S/C21H24FNO/c22-20-8-6-19(7-9-20)21(24)16-18-11-14-23(15-12-18)13-10-17-4-2-1-3-5-17/h1-9,18H,10-16H2 IMURQBPPOHDZAC-UHFFFAOYSA-N 50002220 1-(4-Fluoro-phenyl)-2-(1-phenethyl-piperidin-4-yl)-ethanone::CHEMBL134527 D(2) dopamine receptor 42 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002220&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381687 103916526 CHEMBL134527 ZINC13729942 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761729 OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(F)(F)F InChI=1S/C21H24F3NO/c22-21(23,24)19-8-6-18(7-9-19)20(26)14-16-10-12-25(13-11-16)15-17-4-2-1-3-5-17/h1-9,16,20,26H,10-15H2 CPZOJVSRXNVCFS-UHFFFAOYSA-N 50002215 2-(1-Benzyl-piperidin-4-yl)-1-(4-trifluoromethyl-phenyl)-ethanol; hydrochloride::CHEMBL543437 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002215&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473896 103916521 CHEMBL543437 ZINC13729975 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761732 Fc1ccc(CN2CCC(CC(=O)c3ccc(F)cc3)CC2)cc1 InChI=1S/C20H21F2NO/c21-18-5-1-16(2-6-18)14-23-11-9-15(10-12-23)13-20(24)17-3-7-19(22)8-4-17/h1-8,15H,9-14H2 RTAGZKGOWFALLV-UHFFFAOYSA-N 50002217 2-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-1-(4-fluoro-phenyl)-ethanone::CHEMBL136768 D(2) dopamine receptor 608 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10359210 103916523 CHEMBL136768 ZINC13729933 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761733 C(OC1CC1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C16H23NO/c1-2-4-14(5-3-1)12-17-10-8-15(9-11-17)13-18-16-6-7-16/h1-5,15-16H,6-13H2 CTARQXSEHSYSMH-UHFFFAOYSA-N 50002219 1-Benzyl-4-cyclopropoxymethyl-piperidine; compound with but-2-enedioic acid::CHEMBL344422 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002219&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10354518 103916525 CHEMBL344422 ZINC13730212 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761735 Fc1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C17H22FNO/c18-16-5-3-15(4-6-16)17(20)11-13-7-9-19(10-8-13)12-14-1-2-14/h3-6,13-14H,1-2,7-12H2 KWRMWQDKOGFMKP-UHFFFAOYSA-N 50002218 2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-ethanone; hydrobromide::CHEMBL42228::CHEMBL543412 D(2) dopamine receptor 1630 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002218&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121968 103916524 CHEMBL543412CHEMBL42228 ZINC00004902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761741 CC(=O)c1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C18H25NO2/c1-14(20)17-4-6-18(7-5-17)21-13-16-8-10-19(11-9-16)12-15-2-3-15/h4-7,15-16H,2-3,8-13H2,1H3 LZAQJTAZLIPRTH-UHFFFAOYSA-N 50002223 1-[4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-phenyl]-ethanone::CHEMBL422634 D(2) dopamine receptor 539 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002223&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10334265 103916529 CHEMBL422634 ZINC13730048 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761743 C(Oc1ccc2ccccc2n1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C22H24N2O/c1-2-6-18(7-3-1)16-24-14-12-19(13-15-24)17-25-22-11-10-20-8-4-5-9-21(20)23-22/h1-11,19H,12-17H2 MVAZZLXEJGWWER-UHFFFAOYSA-N 50002230 2-(1-Benzyl-piperidin-4-ylmethoxy)-quinoline; hydrochloride::CHEMBL543674 D(2) dopamine receptor 6300 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002230&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10471973 103916536 CHEMBL543674 ZINC13730206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761745 CCNc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C18H28N2O/c1-2-19-17-5-7-18(8-6-17)21-14-16-9-11-20(12-10-16)13-15-3-4-15/h5-8,15-16,19H,2-4,9-14H2,1H3 RYEDCVJZUMBXFW-UHFFFAOYSA-N 50002228 CHEMBL555544::[4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-phenyl]-ethyl-amine; hydrochloride;0.5hydrate D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002228&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381646 103916534 CHEMBL555544 ZINC13730075 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761754 C(CCOCC1CCN(Cc2ccccc2)CC1)CCc1ccccc1 InChI=1S/C24H33NO/c1-4-10-22(11-5-1)12-8-3-9-19-26-21-24-15-17-25(18-16-24)20-23-13-6-2-7-14-23/h1-2,4-7,10-11,13-14,24H,3,8-9,12,15-21H2 XCCHOGVTIKXTIW-UHFFFAOYSA-N 50002233 1-Benzyl-4-(5-phenyl-pentyloxymethyl)-piperidine; hydrochloride::CHEMBL543440 D(2) dopamine receptor 1850 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002233&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473168 103916539 CHEMBL543440 ZINC13730150 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761757 C(Oc1ccc2ccccc2c1)C1CCN(CC2CC2)CC1 InChI=1S/C20H25NO/c1-2-4-19-13-20(8-7-18(19)3-1)22-15-17-9-11-21(12-10-17)14-16-5-6-16/h1-4,7-8,13,16-17H,5-6,9-12,14-15H2 ANPCCLIAGPFBDJ-UHFFFAOYSA-N 50002240 1-Cyclopropylmethyl-4-(naphthalen-2-yloxymethyl)-piperidine;0.2hydrate::CHEMBL139578 D(2) dopamine receptor 2964 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9971752 103916546 CHEMBL139578 ZINC13730183 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761760 CSc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C17H25NOS/c1-20-17-6-4-16(5-7-17)19-13-15-8-10-18(11-9-15)12-14-2-3-14/h4-7,14-15H,2-3,8-13H2,1H3 CRYRDINSHOZUNA-UHFFFAOYSA-N 50002237 1-Cyclopropylmethyl-4-(4-methylsulfanyl-phenoxymethyl)-piperidine; hydrochloride::CHEMBL545549 D(2) dopamine receptor 1979 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381813 103916543 CHEMBL545549 ZINC13730039 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761761 Nc1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C17H24N2O/c18-16-5-3-15(4-6-16)17(20)11-13-7-9-19(10-8-13)12-14-1-2-14/h3-6,13-14H,1-2,7-12,18H2 AHCCLQJDISTJNU-UHFFFAOYSA-N 50002239 1-(4-Amino-phenyl)-2-(1-cyclopropylmethyl-piperidin-4-yl)-ethanone;0.75hydrate::CHEMBL137163 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002239&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10038912 103916545 CHEMBL137163 ZINC13729927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761765 FC(F)(F)c1ccc(OCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C20H22F3NO/c21-20(22,23)18-6-8-19(9-7-18)25-15-17-10-12-24(13-11-17)14-16-4-2-1-3-5-16/h1-9,17H,10-15H2 NSLABBCHOFZJPV-UHFFFAOYSA-N 50002235 1-Benzyl-4-(4-trifluoromethyl-phenoxymethyl)-piperidine::CHEMBL137768 D(2) dopamine receptor 1930 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002235&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9997949 103916541 CHEMBL137768 ZINC00014951 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761766 C(Oc1cccnc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C18H22N2O/c1-2-5-16(6-3-1)14-20-11-8-17(9-12-20)15-21-18-7-4-10-19-13-18/h1-7,10,13,17H,8-9,11-12,14-15H2 LIEWOYIQRAKJIC-UHFFFAOYSA-N 50002248 3-(1-Benzyl-piperidin-4-ylmethoxy)-pyridine; compound with but-2-enedioic acid;0.5hydrate::CHEMBL138382 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10016641 103916554 CHEMBL138382 ZINC13730209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761769 OC(CC1CCN(CCC2CC2)CC1)c1ccc(F)cc1 InChI=1S/C18H26FNO/c19-17-5-3-16(4-6-17)18(21)13-15-8-11-20(12-9-15)10-7-14-1-2-14/h3-6,14-15,18,21H,1-2,7-13H2 XJVTVQBVIHSXNF-UHFFFAOYSA-N 50002246 2-[1-(2-Cyclopropyl-ethyl)-piperidin-4-yl]-1-(4-fluoro-phenyl)-ethanol::CHEMBL137183 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9971541 103916552 CHEMBL137183 ZINC13729954 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761774 Fc1ccc(COCC2CCN(Cc3ccc(cc3)-c3ccccc3)CC2)cc1 InChI=1S/C26H28FNO/c27-26-12-8-22(9-13-26)19-29-20-23-14-16-28(17-15-23)18-21-6-10-25(11-7-21)24-4-2-1-3-5-24/h1-13,23H,14-20H2 PMTJBCDPEXIPPA-UHFFFAOYSA-N 50002251 1-Biphenyl-4-ylmethyl-4-(4-fluoro-benzyloxymethyl)-piperidine; hydrochloride::CHEMBL545784 D(2) dopamine receptor 818 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10000428 103916557 CHEMBL545784 ZINC13730127 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761776 Fc1c(F)c(F)c(OCC2CCN(CC3CC3)CC2)c(F)c1F InChI=1S/C16H18F5NO/c17-11-12(18)14(20)16(15(21)13(11)19)23-8-10-3-5-22(6-4-10)7-9-1-2-9/h9-10H,1-8H2 OVGYXPASCXSXCK-UHFFFAOYSA-N 50002199 1-Cyclopropylmethyl-4-pentafluorophenyloxymethyl-piperidine; hydrochloride::CHEMBL543438 D(2) dopamine receptor 5684 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10339216 103916505 CHEMBL543438 ZINC13730033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761782 COC(=O)c1ccc(COCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C22H27NO3/c1-25-22(24)21-9-7-19(8-10-21)16-26-17-20-11-13-23(14-12-20)15-18-5-3-2-4-6-18/h2-10,20H,11-17H2,1H3 DCXUTZBPMPWZBF-UHFFFAOYSA-N 50002259 4-(1-Benzyl-piperidin-4-ylmethoxymethyl)-benzoic acid methyl ester; hydrochloride;0.3hydrate::CHEMBL545781 D(2) dopamine receptor 970 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020973 103916565 CHEMBL545781 ZINC13730117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761786 Fc1ccc(OCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C19H22FNO/c20-18-6-8-19(9-7-18)22-15-17-10-12-21(13-11-17)14-16-4-2-1-3-5-16/h1-9,17H,10-15H2 UMBPWJGAKYJPDF-UHFFFAOYSA-N 50002252 1-Benzyl-4-(4-fluoro-phenoxymethyl)-piperidine; hydrochloride;0.1hydrate::CHEMBL539358 D(2) dopamine receptor 870 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063335 103916558 CHEMBL539358 ZINC00005165 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761789 Clc1ccc(OCC2CCN(CC3CC3)CC2)c(Cl)c1 InChI=1S/C16H21Cl2NO/c17-14-3-4-16(15(18)9-14)20-11-13-5-7-19(8-6-13)10-12-1-2-12/h3-4,9,12-13H,1-2,5-8,10-11H2 NYKIBJCOBXAXIE-UHFFFAOYSA-N 50002260 1-Cyclopropylmethyl-4-(2,4-dichloro-phenoxymethyl)-piperidine; hydrochloride::CHEMBL540322 D(2) dopamine receptor 111 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10066510 103916566 CHEMBL540322 ZINC13730072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761790 CC(C)(C)c1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C20H31NO/c1-20(2,3)18-6-8-19(9-7-18)22-15-17-10-12-21(13-11-17)14-16-4-5-16/h6-9,16-17H,4-5,10-15H2,1-3H3 HFMGOZRRGHHPQV-UHFFFAOYSA-N 50002205 4-(4-tert-Butyl-phenoxymethyl)-1-cyclopropylmethyl-piperidine::CHEMBL137563 D(2) dopamine receptor 3154 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002205&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357512 103916511 CHEMBL137563 ZINC13730022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761791 OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2 ZXUYYZPJUGQHLQ-UHFFFAOYSA-N 50002238 (R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::(S)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-1-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-Fluoro-phenyl)-4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol(BMY 14802)::BMY-14802::CHEMBL60859 D(2) dopamine receptor 2431 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 108046 103916544 CHEMBL60859 8 ZINC03995923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761792 OC(CC1CCN(CCc2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C21H26FNO/c22-20-8-6-19(7-9-20)21(24)16-18-11-14-23(15-12-18)13-10-17-4-2-1-3-5-17/h1-9,18,21,24H,10-16H2 QIPBXVRXNZAEGP-UHFFFAOYSA-N 50002262 1-(4-Fluoro-phenyl)-2-(1-phenethyl-piperidin-4-yl)-ethanol;tetrahydrate::CHEMBL136621 D(2) dopamine receptor 806 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002262&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10065025 103916568 CHEMBL136621 ZINC13729981 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761801 [O-][N+](=O)c1ccc(OCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C19H22N2O3/c22-21(23)18-6-8-19(9-7-18)24-15-17-10-12-20(13-11-17)14-16-4-2-1-3-5-16/h1-9,17H,10-15H2 KONVQDMKRAUAHT-UHFFFAOYSA-N 50002266 1-Benzyl-4-(4-nitro-phenoxymethyl)-piperidine; hydrochloride::CHEMBL540578 D(2) dopamine receptor 4386 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10336501 103916572 CHEMBL540578 ZINC00014955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761806 Fc1ccc(OCC2CCN(CCC3CC3)CC2)cc1 InChI=1S/C17H24FNO/c18-16-3-5-17(6-4-16)20-13-15-8-11-19(12-9-15)10-7-14-1-2-14/h3-6,14-15H,1-2,7-13H2 RETHAECAUJXLCA-UHFFFAOYSA-N 50002272 1-(2-Cyclopropyl-ethyl)-4-(4-fluoro-phenoxymethyl)-piperidine; compound with but-2-enedioic acid::CHEMBL423353 D(2) dopamine receptor 428 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10062068 103916578 CHEMBL423353 ZINC13730102 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761807 OC(CC1CCN(Cc2ccccc2)CC1)c1ccco1 InChI=1S/C18H23NO2/c20-17(18-7-4-12-21-18)13-15-8-10-19(11-9-15)14-16-5-2-1-3-6-16/h1-7,12,15,17,20H,8-11,13-14H2 BJSITOKTBWFDIV-UHFFFAOYSA-N 50002274 2-(1-Benzyl-piperidin-4-yl)-1-thiophen-2-yl-ethanol;0.25hydrate::CHEMBL343926 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9994108 103916580 CHEMBL343926 ZINC13730181 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761809 Fc1ccc(cc1)C(=O)CC1CCN(Cc2ccc(cc2)C(F)(F)F)CC1 InChI=1S/C21H21F4NO/c22-19-7-3-17(4-8-19)20(27)13-15-9-11-26(12-10-15)14-16-1-5-18(6-2-16)21(23,24)25/h1-8,15H,9-14H2 AUNWVXAXWYVOSS-UHFFFAOYSA-N 50002250 1-(4-Fluoro-phenyl)-2-[1-(4-trifluoromethyl-benzyl)-piperidin-4-yl]-ethanone::CHEMBL138281 D(2) dopamine receptor 195 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10429790 103916556 CHEMBL138281 ZINC13729930 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761811 Fc1ccc(COCC2CCN(Cc3ccc(Cl)cc3)CC2)cc1 InChI=1S/C20H23ClFNO/c21-19-5-1-16(2-6-19)13-23-11-9-18(10-12-23)15-24-14-17-3-7-20(22)8-4-17/h1-8,18H,9-15H2 BDGDDIFRMSVTFO-UHFFFAOYSA-N 50002241 1-(4-Chloro-benzyl)-4-(4-fluoro-benzyloxymethyl)-piperidine; hydrochloride::CHEMBL539567 D(2) dopamine receptor 488 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020628 103916547 CHEMBL539567 ZINC00014959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761815 COc1ccc(cc1)-c1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C23H29NO2/c1-25-22-8-4-20(5-9-22)21-6-10-23(11-7-21)26-17-19-12-14-24(15-13-19)16-18-2-3-18/h4-11,18-19H,2-3,12-17H2,1H3 DRJKFKHAUSWTAY-UHFFFAOYSA-N 50002276 1-Cyclopropylmethyl-4-(4'-methoxy-biphenyl-4-yloxymethyl)-piperidine;0.5hydrate::CHEMBL136205 D(2) dopamine receptor 7217 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10383330 103916582 CHEMBL136205 ZINC13730060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761821 Fc1ccc(COCC2CCN(CCCc3ccccc3)CC2)cc1 InChI=1S/C22H28FNO/c23-22-10-8-20(9-11-22)17-25-18-21-12-15-24(16-13-21)14-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-11,21H,4,7,12-18H2 ONTHZTBOAGDYQX-UHFFFAOYSA-N 50002282 4-(4-Fluoro-benzyloxymethyl)-1-(3-phenyl-propyl)-piperidine; hydrochloride::CHEMBL552676 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9997424 103916588 CHEMBL552676 ZINC13730121 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761825 [O-][N+](=O)c1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C16H22N2O3/c19-18(20)15-3-5-16(6-4-15)21-12-14-7-9-17(10-8-14)11-13-1-2-13/h3-6,13-14H,1-2,7-12H2 XNJAGXCZRUPRKN-UHFFFAOYSA-N 50002243 1-Cyclopropylmethyl-4-(4-nitro-phenoxymethyl)-piperidine;0.75hydrate::CHEMBL136395::CHEMBL47251 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10334410 103916549 CHEMBL136395CHEMBL47251 ZINC00013940 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761827 Fc1ccc(cc1)S(=O)CC1CCN(CCC2CC2)CC1 InChI=1S/C17H24FNOS/c18-16-3-5-17(6-4-16)21(20)13-15-8-11-19(12-9-15)10-7-14-1-2-14/h3-6,14-15H,1-2,7-13H2 JJEOUSQZJYEUMK-UHFFFAOYSA-N 50002285 1-(2-Cyclopropyl-ethyl)-4-(4-fluoro-benzenesulfinylmethyl)-piperidine::CHEMBL422993 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15147197 103916591 CHEMBL422993 ZINC27439433 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761828 FC(F)(F)c1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C18H22F3NO/c19-18(20,21)16-5-3-15(4-6-16)17(23)11-13-7-9-22(10-8-13)12-14-1-2-14/h3-6,13-14H,1-2,7-12H2 VIXLSHKIMQOVRG-UHFFFAOYSA-N 50002244 2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-trifluoromethyl-phenyl)-ethanone; hydrochloride;0.5hydrate::CHEMBL543917 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11726126 103916550 CHEMBL543917 ZINC13729921 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761830 C(OC1CCCCC1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C19H29NO/c1-3-7-17(8-4-1)15-20-13-11-18(12-14-20)16-21-19-9-5-2-6-10-19/h1,3-4,7-8,18-19H,2,5-6,9-16H2 XHRUGEOTIOLUDU-UHFFFAOYSA-N 50002229 1-Benzyl-4-cyclohexyloxymethyl-piperidine; hydrochloride::CHEMBL544847 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002229&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10039710 103916535 CHEMBL544847 ZINC13730203 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761832 Clc1ccc(OCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C19H22ClNO/c20-18-6-8-19(9-7-18)22-15-17-10-12-21(13-11-17)14-16-4-2-1-3-5-16/h1-9,17H,10-15H2 IHEUAXRYGXAFSS-UHFFFAOYSA-N 50002202 1-Benzyl-4-(4-chloro-phenoxymethyl)-piperidine; hydrochloride::CHEMBL542246 D(2) dopamine receptor 4212 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002202&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973032 103916508 CHEMBL542246 ZINC00014948 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761834 Fc1ccc(CC(=O)C2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C20H22FNO/c21-19-8-6-16(7-9-19)14-20(23)18-10-12-22(13-11-18)15-17-4-2-1-3-5-17/h1-9,18H,10-15H2 JTLLMTUMOOUYPU-UHFFFAOYSA-N 50002280 1-(1-Benzyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-ethanone; compound with but-2-enedioic acid;0.75hydrate::CHEMBL442965 D(2) dopamine receptor 4561 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025540 103916586 CHEMBL442965 ZINC00014993 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761836 C(Oc1ncccn1)C1CCN(CC2CC2)CC1 InChI=1S/C14H21N3O/c1-6-15-14(16-7-1)18-11-13-4-8-17(9-5-13)10-12-2-3-12/h1,6-7,12-13H,2-5,8-11H2 UQCMDZMOZPGVIY-UHFFFAOYSA-N 50002281 2-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-pyrimidine; hydrochloride::CHEMBL539291 D(2) dopamine receptor 4445 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264006 103916587 CHEMBL539291 ZINC13730192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761839 C(Oc1ccncc1)C1CCN(CC2CC2)CC1 InChI=1S/C15H22N2O/c1-2-13(1)11-17-9-5-14(6-10-17)12-18-15-3-7-16-8-4-15/h3-4,7-8,13-14H,1-2,5-6,9-12H2 LJNOPIFTNMRKTL-UHFFFAOYSA-N 50002206 4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-pyridine;0.25hydrate::CHEMBL139102 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002206&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377272 103916512 CHEMBL139102 ZINC13730186 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761843 Fc1ccc(OCC2CCN(Cc3ccc4ccccc4c3)CC2)cc1 InChI=1S/C23H24FNO/c24-22-7-9-23(10-8-22)26-17-18-11-13-25(14-12-18)16-19-5-6-20-3-1-2-4-21(20)15-19/h1-10,15,18H,11-14,16-17H2 SNXVBAOOINCPOX-UHFFFAOYSA-N 50002287 4-(4-Fluoro-phenoxymethyl)-1-naphthalen-2-ylmethyl-piperidine::CHEMBL440345 D(2) dopamine receptor 4336 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10450490 103916593 CHEMBL440345 ZINC00014950 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761845 Fc1ccc(COCC2CCN(Cc3ccc(OCc4ccccc4)cc3)CC2)cc1 InChI=1S/C27H30FNO2/c28-26-10-6-24(7-11-26)19-30-20-25-14-16-29(17-15-25)18-22-8-12-27(13-9-22)31-21-23-4-2-1-3-5-23/h1-13,25H,14-21H2 DLRMDAMHGPXZDZ-UHFFFAOYSA-N 50002289 1-(4-Benzyloxy-benzyl)-4-(4-fluoro-benzyloxymethyl)-piperidine; hydrochloride::CHEMBL545081 D(2) dopamine receptor 773 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025089 103916595 CHEMBL545081 ZINC13730129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761849 Oc1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H23NO2/c22-19-8-6-18(7-9-19)20(23)14-16-10-12-21(13-11-16)15-17-4-2-1-3-5-17/h1-9,16,22H,10-15H2 PCPKGFDUJAITQP-UHFFFAOYSA-N 50002195 2-(1-Benzyl-piperidin-4-yl)-1-(4-hydroxy-phenyl)-ethanone;0.25hydrate::CHEMBL344240 D(2) dopamine receptor 1345 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425446 103916501 CHEMBL344240 ZINC13729898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761850 C(Oc1ccc(Oc2ccccc2)cc1)C1CCN(CC2CC2)CC1 InChI=1S/C22H27NO2/c1-2-4-21(5-3-1)25-22-10-8-20(9-11-22)24-17-19-12-14-23(15-13-19)16-18-6-7-18/h1-5,8-11,18-19H,6-7,12-17H2 VDAGLALCXOCSPL-UHFFFAOYSA-N 50002224 1-Cyclopropylmethyl-4-(4-phenoxy-phenoxymethyl)-piperidine::CHEMBL337711 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002224&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10472266 103916530 CHEMBL337711 ZINC13730054 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761852 Fc1ccc(OCC2CCN(Cc3ccncc3)CC2)cc1 InChI=1S/C18H21FN2O/c19-17-1-3-18(4-2-17)22-14-16-7-11-21(12-8-16)13-15-5-9-20-10-6-15/h1-6,9-10,16H,7-8,11-14H2 FCTXVIRWLWVYPI-UHFFFAOYSA-N 50002236 4-[4-(4-Fluoro-phenoxymethyl)-piperidin-1-ylmethyl]-pyridine;0.25hydrate::CHEMBL136381 D(2) dopamine receptor 2753 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10447534 103916542 CHEMBL136381 ZINC00014953 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761854 CC1(CN2CCC(COc3ccc(F)cc3)CC2)CC1(Cl)Cl InChI=1S/C17H22Cl2FNO/c1-16(11-17(16,18)19)12-21-8-6-13(7-9-21)10-22-15-4-2-14(20)3-5-15/h2-5,13H,6-12H2,1H3 KHCPDPQMFDMOCU-UHFFFAOYSA-N 50002209 1-(2,2-Dichloro-1-methyl-cyclopropylmethyl)-4-(4-fluoro-phenoxymethyl)-piperidine; compound with but-2-enedioic acid::CHEMBL136615 D(2) dopamine receptor 179 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002209&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10004517 103916515 CHEMBL136615 ZINC13730093 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761859 Fc1ccc(COCC2CCN(Cc3ccncc3)CC2)cc1 InChI=1S/C19H23FN2O/c20-19-3-1-17(2-4-19)14-23-15-18-7-11-22(12-8-18)13-16-5-9-21-10-6-16/h1-6,9-10,18H,7-8,11-15H2 ZYCNEMMIUJZVCN-UHFFFAOYSA-N 50002292 4-[4-(4-Fluoro-benzyloxymethyl)-piperidin-1-ylmethyl]-pyridine; compound with but-2-enedioic acid::CHEMBL134684 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002292&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10335795 103916598 CHEMBL134684 ZINC13730132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761862 OC(Cc1ccc(F)cc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24FNO/c21-19-8-6-16(7-9-19)14-20(23)18-10-12-22(13-11-18)15-17-4-2-1-3-5-17/h1-9,18,20,23H,10-15H2 GGLXYEKODZVCAR-UHFFFAOYSA-N 50002187 1-(1-Benzyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-ethanol; hydrochloride;0.25hydrate::CHEMBL545546 D(2) dopamine receptor 789 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10066435 103916493 CHEMBL545546 ZINC13729985 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761869 CSc1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H25NOS/c1-24-20-9-7-19(8-10-20)21(23)15-17-11-13-22(14-12-17)16-18-5-3-2-4-6-18/h2-10,17H,11-16H2,1H3 CQTIFTMVBRSADW-UHFFFAOYSA-N 50002226 2-(1-Benzyl-piperidin-4-yl)-1-(4-methylsulfanyl-phenyl)-ethanone::CHEMBL136789 D(2) dopamine receptor 715 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002226&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020103 103916532 CHEMBL136789 ZINC13729895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761878 OC(CC1CCN(Cc2ccccc2)CC1)c1cccs1 InChI=1S/C18H23NOS/c20-17(18-7-4-12-21-18)13-15-8-10-19(11-9-15)14-16-5-2-1-3-6-16/h1-7,12,15,17,20H,8-11,13-14H2 YRZCOTAEWIJNFD-UHFFFAOYSA-N 50002264 2-(1-Benzyl-piperidin-4-yl)-1-thiophen-2-yl-ethanol;0.25hydrate::CHEMBL139370 D(2) dopamine receptor 3717 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002264&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9972102 103916570 CHEMBL139370 ZINC13730176 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761879 Fc1ccc(COCC2CCN(CC3CCCCC3)CC2)cc1 InChI=1S/C20H30FNO/c21-20-8-6-18(7-9-20)15-23-16-19-10-12-22(13-11-19)14-17-4-2-1-3-5-17/h6-9,17,19H,1-5,10-16H2 MCUMVFJXBCETBP-UHFFFAOYSA-N 50002263 1-Cyclohexylmethyl-4-(4-fluoro-benzyloxymethyl)-piperidine; hydrochloride::CHEMBL542737 D(2) dopamine receptor 3350 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002263&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10313896 103916569 CHEMBL542737 ZINC00014960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761880 OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C20H24FNO/c21-19-8-6-18(7-9-19)20(23)14-16-10-12-22(13-11-16)15-17-4-2-1-3-5-17/h1-9,16,20,23H,10-15H2 ZYRWINLYTSWVNM-UHFFFAOYSA-N 50002291 2-(1-Benzyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-ethanol; hydrochloride::CHEMBL555443 D(2) dopamine receptor 5658 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10337918 103916597 CHEMBL555443 ZINC13729957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761881 Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccc(Cl)cc2)CC1 InChI=1S/C21H23ClFNO/c22-19-5-1-16(2-6-19)9-12-24-13-10-17(11-14-24)15-21(25)18-3-7-20(23)8-4-18/h1-8,17H,9-15H2 IHZMBRPMQIFTMC-UHFFFAOYSA-N 50002242 2-{1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-4-yl}-1-(4-fluoro-phenyl)-ethanone::CHEMBL139963 D(2) dopamine receptor 14 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002242&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10316441 103916548 CHEMBL139963 ZINC13729943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761884 COc1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C18H25NO2/c1-21-17-6-4-16(5-7-17)18(20)12-14-8-10-19(11-9-14)13-15-2-3-15/h4-7,14-15H,2-3,8-13H2,1H3 SOBSFPZFIBOWGB-UHFFFAOYSA-N 50002253 2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-methoxy-phenyl)-ethanone; hydrobromide::CHEMBL543910 D(2) dopamine receptor 1802 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10384384 103916559 CHEMBL543910 ZINC13729915 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761886 C(CCc1ccccc1)COCC1CCN(Cc2ccccc2)CC1 InChI=1S/C23H31NO/c1-3-9-21(10-4-1)11-7-8-18-25-20-23-14-16-24(17-15-23)19-22-12-5-2-6-13-22/h1-6,9-10,12-13,23H,7-8,11,14-20H2 CSCXMSDQXSMINC-UHFFFAOYSA-N 50002232 1-Benzyl-4-(4-phenyl-butoxymethyl)-piperidine; hydrochloride::CHEMBL554678 D(2) dopamine receptor 4340 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002232&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11724647 103916538 CHEMBL554678 ZINC13730147 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761888 Fc1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H22FNO/c21-19-8-6-18(7-9-19)20(23)14-16-10-12-22(13-11-16)15-17-4-2-1-3-5-17/h1-9,16H,10-15H2 WJDNTXQROCWPDH-UHFFFAOYSA-N 50002254 2-(1-Benzyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-ethanone; compound with but-2-enedioic acid;0.25hydrate::CHEMBL342267 D(2) dopamine receptor 1550 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9926747 103916560 CHEMBL342267 ZINC00005172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761890 OCc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C17H25NO2/c19-12-15-3-5-17(6-4-15)20-13-16-7-9-18(10-8-16)11-14-1-2-14/h3-6,14,16,19H,1-2,7-13H2 DRHLUSIUCNGTDR-UHFFFAOYSA-N 50002299 CHEMBL136877::[4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-phenyl]-methanol;0.3hydrate D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10356045 103916605 CHEMBL136877 ZINC13730019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761893 C(Oc1ccccn1)C1CCN(CC2CC2)CC1 InChI=1S/C15H22N2O/c1-2-8-16-15(3-1)18-12-14-6-9-17(10-7-14)11-13-4-5-13/h1-3,8,13-14H,4-7,9-12H2 QBEQOIRJXCLYNQ-UHFFFAOYSA-N 50002231 2-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-pyridine; hydrochloride::CHEMBL540066 D(2) dopamine receptor 4667 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002231&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10467116 103916537 CHEMBL540066 ZINC13730194 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761896 C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1 InChI=1S/C21H27N3/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3/t16-,17+ GUDVQJXODNJRIJ-CALCHBBNSA-N 50019742 9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-(3-(3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-[3-((3R,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3S,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole (Rimcazole) (BW234U)::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole(rimcazole)::CHEMBL275707::RIMCAZOLE D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53389 103930665 CHEMBL275707 ZINC22920326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761899 C(OCc1ccccc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C20H25NO/c1-3-7-18(8-4-1)15-21-13-11-20(12-14-21)17-22-16-19-9-5-2-6-10-19/h1-10,20H,11-17H2 CHUMPFKYVVLYMQ-UHFFFAOYSA-N 50002222 1-Benzyl-4-benzyloxymethyl-piperidine; hydrochloride::CHEMBL544146 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063111 103916528 CHEMBL544146 ZINC13730114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761901 Oc1ccc(CN2CCC(COCc3ccc(F)cc3)CC2)cc1 InChI=1S/C20H24FNO2/c21-19-5-1-17(2-6-19)14-24-15-18-9-11-22(12-10-18)13-16-3-7-20(23)8-4-16/h1-8,18,23H,9-15H2 OMXNVQLATBAEOI-UHFFFAOYSA-N 50002295 4-[4-(4-Fluoro-benzyloxymethyl)-piperidin-1-ylmethyl]-phenol; hydrochloride::CHEMBL544147 D(2) dopamine receptor 3135 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002295&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11724125 103916601 CHEMBL544147 ZINC00014961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761906 Fc1ccc(cc1)C(=O)CC1CCN(CCC2CC2)CC1 InChI=1S/C18H24FNO/c19-17-5-3-16(4-6-17)18(21)13-15-8-11-20(12-9-15)10-7-14-1-2-14/h3-6,14-15H,1-2,7-13H2 SIVYVSDTKDABLS-UHFFFAOYSA-N 50002298 2-[1-(2-Cyclopropyl-ethyl)-piperidin-4-yl]-1-(4-fluoro-phenyl)-ethanone; hydrobromide::CHEMBL544616 D(2) dopamine receptor 220 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002298&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10248560 103916604 CHEMBL544616 ZINC13729949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761907 CC(C)(C)c1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C21H31NO/c1-21(2,3)19-8-6-18(7-9-19)20(23)14-16-10-12-22(13-11-16)15-17-4-5-17/h6-9,16-17H,4-5,10-15H2,1-3H3 CSTCXYFZARVQDX-UHFFFAOYSA-N 50002302 1-(4-tert-Butyl-phenyl)-2-(1-cyclopropylmethyl-piperidin-4-yl)-ethanone; hydrobromide;0.5hydrate::CHEMBL555975 D(2) dopamine receptor 1573 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430713 103916608 CHEMBL555975 ZINC13729918 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761916 COc1ccc(COCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C21H27NO2/c1-23-21-9-7-19(8-10-21)16-24-17-20-11-13-22(14-12-20)15-18-5-3-2-4-6-18/h2-10,20H,11-17H2,1H3 MQWNWBIMTZBMCY-UHFFFAOYSA-N 50002267 1-Benzyl-4-(4-methoxy-benzyloxymethyl)-piperidine; compound with but-2-enedioic acid::CHEMBL136429 D(2) dopamine receptor 26000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10336465 103916573 CHEMBL136429 ZINC13730108 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761917 Clc1ccc(OCC2CCN(CC3CC3)CC2)cc1Cl InChI=1S/C16H21Cl2NO/c17-15-4-3-14(9-16(15)18)20-11-13-5-7-19(8-6-13)10-12-1-2-12/h3-4,9,12-13H,1-2,5-8,10-11H2 JBOSNMFKECOBMB-UHFFFAOYSA-N 50002212 1-Cyclopropylmethyl-4-(3,4-dichloro-phenoxymethyl)-piperidine; hydrochloride::CHEMBL543439 D(2) dopamine receptor 1652 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002212&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10383267 103916518 CHEMBL543439 ZINC13730069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761918 OCc1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H25NO2/c23-16-19-6-8-20(9-7-19)21(24)14-17-10-12-22(13-11-17)15-18-4-2-1-3-5-18/h1-9,17,23H,10-16H2 FLJUGLHPEGJBNI-UHFFFAOYSA-N 50002188 2-(1-Benzyl-piperidin-4-yl)-1-(4-hydroxymethyl-phenyl)-ethanone;0.5hydrate::CHEMBL136388 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002188&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10019100 103916494 CHEMBL136388 ZINC13729903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761922 OC(Cc1ccc(F)cc1)C1CCN(CCCc2ccccc2)CC1 InChI=1S/C22H28FNO/c23-21-10-8-19(9-11-21)17-22(25)20-12-15-24(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,22,25H,4,7,12-17H2 NWHFTMRBTIYJST-UHFFFAOYSA-N 50002265 2-(4-Fluoro-phenyl)-1-[1-(3-phenyl-propyl)-piperidin-4-yl]-ethanol;0.1hydrate::CHEMBL136701 D(2) dopamine receptor 1700 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10315281 103916571 CHEMBL136701 ZINC13729997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761923 C(Oc1ccc(cc1)-c1ccccc1)C1CCN(CC2CC2)CC1 InChI=1S/C22H27NO/c1-2-4-20(5-3-1)21-8-10-22(11-9-21)24-17-19-12-14-23(15-13-19)16-18-6-7-18/h1-5,8-11,18-19H,6-7,12-17H2 ZTJKKEYVPLJHEN-UHFFFAOYSA-N 50002273 4-(Biphenyl-4-yloxymethyl)-1-cyclopropylmethyl-piperidine;0.1hydrate::CHEMBL335019 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10448770 103916579 CHEMBL335019 ZINC13730017 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761925 COc1cc(OCC2CCN(CC3CC3)CC2)cc(OC)c1OC InChI=1S/C19H29NO4/c1-21-17-10-16(11-18(22-2)19(17)23-3)24-13-15-6-8-20(9-7-15)12-14-4-5-14/h10-11,14-15H,4-9,12-13H2,1-3H3 OPIIETNQMDQTFZ-UHFFFAOYSA-N 50002296 1-Cyclopropylmethyl-4-(3,4,5-trimethoxy-phenoxymethyl)-piperidine; hydrochloride::CHEMBL541603 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10339224 103916602 CHEMBL541603 ZINC13730036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761926 COc1ccc(OCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C20H25NO2/c1-22-19-7-9-20(10-8-19)23-16-18-11-13-21(14-12-18)15-17-5-3-2-4-6-17/h2-10,18H,11-16H2,1H3 XJQOYNYWSCZFJK-UHFFFAOYSA-N 50002284 1-Benzyl-4-(4-methoxy-phenoxymethyl)-piperidine::CHEMBL137159 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002284&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10018369 103916590 CHEMBL137159 ZINC13730096 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761927 Fc1ccc(cc1)C(=O)CC1CCCN(CC2CC2)C1 InChI=1S/C17H22FNO/c18-16-7-5-15(6-8-16)17(20)10-14-2-1-9-19(12-14)11-13-3-4-13/h5-8,13-14H,1-4,9-12H2 WUTBBDJCGXNAOM-UHFFFAOYSA-N 50002297 2-(1-Cyclopropylmethyl-piperidin-3-yl)-1-(4-fluoro-phenyl)-ethanone::CHEMBL136743 D(2) dopamine receptor 185 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002297&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12364511 103916603 CHEMBL136743 ZINC27438188 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761929 Fc1ccc(CCN2CCC(CC(=O)c3ccc(F)cc3)CC2)cc1 InChI=1S/C21H23F2NO/c22-19-5-1-16(2-6-19)9-12-24-13-10-17(11-14-24)15-21(25)18-3-7-20(23)8-4-18/h1-8,17H,9-15H2 LDOQDGKJZFBHAG-UHFFFAOYSA-N 50002198 1-(4-Fluoro-phenyl)-2-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-ethanone::CHEMBL337337 D(2) dopamine receptor 57 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002198&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10360079 103916504 CHEMBL337337 ZINC13729939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761933 O=C(CC1CCN(CC2CC2)CC1)c1ccc(cc1)-c1ccccc1 InChI=1S/C23H27NO/c25-23(16-18-12-14-24(15-13-18)17-19-6-7-19)22-10-8-21(9-11-22)20-4-2-1-3-5-20/h1-5,8-11,18-19H,6-7,12-17H2 YOTNUCOJHZBCRU-UHFFFAOYSA-N 50002278 1-Biphenyl-4-yl-2-(1-cyclopropylmethyl-piperidin-4-yl)-ethanone; hydrobromide::CHEMBL544372 D(2) dopamine receptor 1718 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742510 103916584 CHEMBL544372 ZINC01493035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761938 Fc1ccc(OCCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C20H24FNO/c21-19-6-8-20(9-7-19)23-15-12-17-10-13-22(14-11-17)16-18-4-2-1-3-5-18/h1-9,17H,10-16H2 IRGCLOHNAHIYPC-UHFFFAOYSA-N 50002290 1-Benzyl-4-[2-(4-fluoro-phenoxy)-ethyl]-piperidine; hydrochloride;0.2hydrate::CHEMBL540585 D(2) dopamine receptor 114 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9926836 103916596 CHEMBL540585 ZINC00014957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761940 FC(F)(F)c1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H22F3NO/c22-21(23,24)19-8-6-18(7-9-19)20(26)14-16-10-12-25(13-11-16)15-17-4-2-1-3-5-17/h1-9,16H,10-15H2 JWAIMOQKOOQZSI-UHFFFAOYSA-N 50002249 2-(1-Benzyl-piperidin-4-yl)-1-(4-trifluoromethyl-phenyl)-ethanone;0.25hydrate::CHEMBL136068 D(2) dopamine receptor 4667 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10089975 103916555 CHEMBL136068 ZINC13729889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761941 CC(C)(C)c1ccc(COCCC2CCN(Cc3ccccc3)CC2)cc1 InChI=1S/C25H35NO/c1-25(2,3)24-11-9-23(10-12-24)20-27-18-15-21-13-16-26(17-14-21)19-22-7-5-4-6-8-22/h4-12,21H,13-20H2,1-3H3 ZSDRHKRYDSPJQZ-UHFFFAOYSA-N 50002225 1-Benzyl-4-[2-(4-tert-butyl-benzyloxy)-ethyl]-piperidine; hydrochloride::CHEMBL539553 D(2) dopamine receptor 6753 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002225&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9976112 103916531 CHEMBL539553 ZINC13730153 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761945 CN(C)c1cccc(OCC2CCN(CC3CC3)CC2)c1 InChI=1S/C18H28N2O/c1-19(2)17-4-3-5-18(12-17)21-14-16-8-10-20(11-9-16)13-15-6-7-15/h3-5,12,15-16H,6-11,13-14H2,1-2H3 QGAPHPYAEAZBIR-UHFFFAOYSA-N 50002286 CHEMBL439609::[3-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-phenyl]-dimethyl-amine;0.1hydrate D(2) dopamine receptor 7326 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10401867 103916592 CHEMBL439609 ZINC13730066 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761946 Fc1ccc(OCC2CCN(CC3CC3)CC2)cc1F InChI=1S/C16H21F2NO/c17-15-4-3-14(9-16(15)18)20-11-13-5-7-19(8-6-13)10-12-1-2-12/h3-4,9,12-13H,1-2,5-8,10-11H2 JCZXZJHHGGQSSI-UHFFFAOYSA-N 50002303 1-Cyclopropylmethyl-4-(3,4-difluoro-phenoxymethyl)-piperidine; hydrochloride::CHEMBL538532 D(2) dopamine receptor 2836 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973146 103916609 CHEMBL538532 ZINC13730030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761947 Fc1ccc(CC(=O)C2CCN(CCCC(=O)c3ccc(F)cc3)CC2)cc1 InChI=1S/C23H25F2NO2/c24-20-7-3-17(4-8-20)16-23(28)19-11-14-26(15-12-19)13-1-2-22(27)18-5-9-21(25)10-6-18/h3-10,19H,1-2,11-16H2 YRVVMHBYSCLKFD-UHFFFAOYSA-N 50002234 1-(4-Fluoro-phenyl)-4-{4-[2-(4-fluoro-phenyl)-acetyl]-piperidin-1-yl}-butan-1-one::CHEMBL136509 D(2) dopamine receptor 55 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10407739 103916540 CHEMBL136509 ZINC13730010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761954 CS(=O)(=O)c1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H25NO3S/c1-26(24,25)20-9-7-19(8-10-20)21(23)15-17-11-13-22(14-12-17)16-18-5-3-2-4-6-18/h2-10,17H,11-16H2,1H3 ZFNICZSXJSDSLP-UHFFFAOYSA-N 50002201 2-(1-Benzyl-piperidin-4-yl)-1-(4-methanesulfonyl-phenyl)-ethanone::CHEMBL342948 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002201&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9976497 103916507 CHEMBL342948 ZINC13729906 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761957 Fc1ccc(SCC2CCN(CCC3CC3)CC2)cc1 InChI=1S/C17H24FNS/c18-16-3-5-17(6-4-16)20-13-15-8-11-19(12-9-15)10-7-14-1-2-14/h3-6,14-15H,1-2,7-13H2 OFCRYZNFAWFDNB-UHFFFAOYSA-N 50002216 1-(2-Cyclopropyl-ethyl)-4-(4-fluoro-phenylsulfanylmethyl)-piperidine::CHEMBL137321 D(2) dopamine receptor 1702 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002216&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15147193 103916522 CHEMBL137321 ZINC27431626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761961 Fc1ccc(cc1)C(=O)CC1CCCCN1Cc1ccccc1 InChI=1S/C20H22FNO/c21-18-11-9-17(10-12-18)20(23)14-19-8-4-5-13-22(19)15-16-6-2-1-3-7-16/h1-3,6-7,9-12,19H,4-5,8,13-15H2 SEKACYIABBPRDN-UHFFFAOYSA-N 50002304 2-(1-Benzyl-piperidin-2-yl)-1-(4-fluoro-phenyl)-ethanone; compound with but-2-enedioic acid::CHEMBL136589 D(2) dopamine receptor 3344 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002304&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425590 103916610 CHEMBL136589 ZINC27441626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761962 Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccc(cc2)C(F)(F)F)CC1 InChI=1S/C22H23F4NO/c23-20-7-3-18(4-8-20)21(28)15-17-10-13-27(14-11-17)12-9-16-1-5-19(6-2-16)22(24,25)26/h1-8,17H,9-15H2 JXDNMESNLICMIF-UHFFFAOYSA-N 50002288 1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phenyl)-ethyl]-piperidin-4-yl}-ethanone::CHEMBL136794 D(2) dopamine receptor 10 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002288&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10023485 103916594 CHEMBL136794 ZINC13729946 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761967 CCCCCN1CCC(COCc2ccc(F)cc2)CC1 InChI=1S/C18H28FNO/c1-2-3-4-11-20-12-9-17(10-13-20)15-21-14-16-5-7-18(19)8-6-16/h5-8,17H,2-4,9-15H2,1H3 UFCJKZJIFJHWCB-UHFFFAOYSA-N 50002277 4-(4-Fluoro-benzyloxymethyl)-1-pentyl-piperidine; hydrochloride::CHEMBL555093 D(2) dopamine receptor 1321 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10108459 103916583 CHEMBL555093 ZINC13730138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761968 Fc1ccc(cc1)C(=O)CC1CCN(CCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25FN2O/c24-20-7-5-18(6-8-20)23(27)15-17-9-12-26(13-10-17)14-11-19-16-25-22-4-2-1-3-21(19)22/h1-8,16-17,25H,9-15H2 CDSLIIIUAQZQPQ-UHFFFAOYSA-N 50002213 1-(4-Fluoro-phenyl)-2-{1-[2-(1H-indol-3-yl)-ethyl]-piperidin-4-yl}-ethanone;monohydrate::CHEMBL136064 D(2) dopamine receptor 7 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002213&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10384175 103916519 CHEMBL136064 ZINC13729936 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761973 O=C(CC1CCN(Cc2ccccc2)CC1)c1ccc(cc1)-c1ccccc1 InChI=1S/C26H27NO/c28-26(25-13-11-24(12-14-25)23-9-5-2-6-10-23)19-21-15-17-27(18-16-21)20-22-7-3-1-4-8-22/h1-14,21H,15-20H2 NBVKYCVNARXEHZ-UHFFFAOYSA-N 50002258 CHEMBL422627::c2-(1-Benzyl-piperidin-4-yl)-1-biphenyl-4-yl-ethanone D(2) dopamine receptor 3009 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10317034 103916564 CHEMBL422627 ZINC13729900 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761976 C(Oc1ccc2ccccc2c1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C23H25NO/c1-2-6-19(7-3-1)17-24-14-12-20(13-15-24)18-25-23-11-10-21-8-4-5-9-22(21)16-23/h1-11,16,20H,12-15,17-18H2 BQNYHHARNBWQMF-UHFFFAOYSA-N 50002247 1-Benzyl-4-(naphthalen-2-yloxymethyl)-piperidine;0.75hydrate::CHEMBL424281 D(2) dopamine receptor 1022 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10471910 103916553 CHEMBL424281 ZINC13730200 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761978 COC(=O)c1ccc(CN2CCC(COCc3ccc(F)cc3)CC2)cc1 InChI=1S/C22H26FNO3/c1-26-22(25)20-6-2-17(3-7-20)14-24-12-10-19(11-13-24)16-27-15-18-4-8-21(23)9-5-18/h2-9,19H,10-16H2,1H3 PHEZTZVFWVWYHP-UHFFFAOYSA-N 50002255 4-[4-(4-Fluoro-benzyloxymethyl)-piperidin-1-ylmethyl]-benzoic acid methyl ester; hydrochloride::CHEMBL558819 D(2) dopamine receptor 1980 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10022118 103916561 CHEMBL558819 ZINC13730124 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761983 Fc1ccc(COCC2CCN(Cc3cccc4ccccc34)CC2)cc1 InChI=1S/C24H26FNO/c25-23-10-8-19(9-11-23)17-27-18-20-12-14-26(15-13-20)16-22-6-3-5-21-4-1-2-7-24(21)22/h1-11,20H,12-18H2 CCVCUCIRQWESOG-UHFFFAOYSA-N 50002301 4-(4-Fluoro-benzyloxymethyl)-1-naphthalen-1-ylmethyl-piperidine; hydrochloride::CHEMBL545552 D(2) dopamine receptor 219 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473916 103916607 CHEMBL545552 ZINC00599619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761988 Fc1ccc(COCC2CCN(Cc3ccc4ccccc4c3)CC2)cc1 InChI=1S/C24H26FNO/c25-24-9-6-19(7-10-24)17-27-18-20-11-13-26(14-12-20)16-21-5-8-22-3-1-2-4-23(22)15-21/h1-10,15,20H,11-14,16-18H2 RCIYLLFFBXNPBQ-UHFFFAOYSA-N 50002256 4-(4-Fluoro-benzyloxymethyl)-1-naphthalen-2-ylmethyl-piperidine; hydrochloride::CHEMBL542740 D(2) dopamine receptor 305 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406416 103916562 CHEMBL542740 ZINC13730135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761989 CS(=O)(=O)c1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C17H25NO3S/c1-22(19,20)17-6-4-16(5-7-17)21-13-15-8-10-18(11-9-15)12-14-2-3-14/h4-7,14-15H,2-3,8-13H2,1H3 ZAQNWWFJFHEQJS-UHFFFAOYSA-N 50002191 1-Cyclopropylmethyl-4-(4-methanesulfonyl-phenoxymethyl)-piperidine::CHEMBL136590 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10041895 103916497 CHEMBL136590 ZINC13730042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761991 Fc1ccc(CC(=O)C2CCN(Cc3ccncc3)CC2)cc1 InChI=1S/C19H21FN2O/c20-18-3-1-15(2-4-18)13-19(23)17-7-11-22(12-8-17)14-16-5-9-21-10-6-16/h1-6,9-10,17H,7-8,11-14H2 OIOZNWCZHDMAHS-UHFFFAOYSA-N 50002227 2-(4-Fluoro-phenyl)-1-(1-pyridin-4-ylmethyl-piperidin-4-yl)-ethanone; compound with dibut-2-enedioic acid;0.75hydrate::CHEMBL337124 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002227&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10437382 103916533 CHEMBL337124 ZINC00014994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761995 Fc1ccc(COCC2CCN(CCc3ccccc3)CC2)cc1 InChI=1S/C21H26FNO/c22-21-8-6-19(7-9-21)16-24-17-20-11-14-23(15-12-20)13-10-18-4-2-1-3-5-18/h1-9,20H,10-17H2 QXYCLOCXKREGEY-UHFFFAOYSA-N 50002194 4-(4-Fluoro-benzyloxymethyl)-1-phenethyl-piperidine; compound with but-2-enedioic acid::CHEMBL136963 D(2) dopamine receptor 560 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002194&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381798 103916500 CHEMBL136963 ZINC00014956 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761999 C(Oc1ccccc1)C1CCN(CC2CC2)CC1 InChI=1S/C16H23NO/c1-2-4-16(5-3-1)18-13-15-8-10-17(11-9-15)12-14-6-7-14/h1-5,14-15H,6-13H2 LBTGMWREZZLOAH-UHFFFAOYSA-N 50002196 1-Cyclopropylmethyl-4-phenoxymethyl-piperidine::CHEMBL139110 D(2) dopamine receptor 3169 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002196&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10421988 103916502 CHEMBL139110 ZINC13730063 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762004 C(Oc1ccc2[nH]ccc2c1)C1CCN(CC2CC2)CC1 InChI=1S/C18H24N2O/c1-2-14(1)12-20-9-6-15(7-10-20)13-21-17-3-4-18-16(11-17)5-8-19-18/h3-5,8,11,14-15,19H,1-2,6-7,9-10,12-13H2 GYBWSNJGOJUGRI-UHFFFAOYSA-N 50002192 5-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-1H-indole::CHEMBL423355 D(2) dopamine receptor 2349 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10062442 103916498 CHEMBL423355 ZINC13730197 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762005 C(Oc1ccnc2ccccc12)C1CCN(CC2CC2)CC1 InChI=1S/C19H24N2O/c1-2-4-18-17(3-1)19(7-10-20-18)22-14-16-8-11-21(12-9-16)13-15-5-6-15/h1-4,7,10,15-16H,5-6,8-9,11-14H2 UWSDQWLPHZNNBG-UHFFFAOYSA-N 50002261 4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-quinoline;0.75hydrate::CHEMBL137502 D(2) dopamine receptor 4847 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002261&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379834 103916567 CHEMBL137502 ZINC13730189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762007 COc1ccc(CN2CCC(COc3ccc(F)cc3)CC2)cc1 InChI=1S/C20H24FNO2/c1-23-19-6-2-16(3-7-19)14-22-12-10-17(11-13-22)15-24-20-8-4-18(21)5-9-20/h2-9,17H,10-15H2,1H3 LEBJQHZCSIQTPM-UHFFFAOYSA-N 50002306 4-(4-Fluoro-phenoxymethyl)-1-(4-methoxy-benzyl)-piperidine; compound with but-2-enedioic acid;0.5hydrate::CHEMBL343802 D(2) dopamine receptor 1340 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9996676 103916612 CHEMBL343802 ZINC00014952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762012 Clc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C16H22ClNO/c17-15-3-5-16(6-4-15)19-12-14-7-9-18(10-8-14)11-13-1-2-13/h3-6,13-14H,1-2,7-12H2 SQRXAJRZEFTEFS-UHFFFAOYSA-N 50002293 4-(4-Chloro-phenoxymethyl)-1-cyclopropylmethyl-piperidine; hydrochloride::CHEMBL539302 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381019 103916599 CHEMBL539302 ZINC00013939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762015 Fc1ccc(OCC2CCN(CCc3ccc(Cl)cc3)CC2)cc1 InChI=1S/C20H23ClFNO/c21-18-3-1-16(2-4-18)9-12-23-13-10-17(11-14-23)15-24-20-7-5-19(22)6-8-20/h1-8,17H,9-15H2 DHCOINUZJXKBOU-UHFFFAOYSA-N 50002221 1-[2-(4-Chloro-phenyl)-ethyl]-4-(4-fluoro-phenoxymethyl)-piperidine; hydrochloride::CHEMBL555865 D(2) dopamine receptor 368 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10427805 103916527 CHEMBL555865 ZINC13730099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762017 OC(Cc1ccc(F)cc1)C1CCN(CCCCc2ccccc2)CC1 InChI=1S/C23H30FNO/c24-22-11-9-20(10-12-22)18-23(26)21-13-16-25(17-14-21)15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,9-12,21,23,26H,4-5,8,13-18H2 FIFLUTNSIVHHPL-UHFFFAOYSA-N 50002271 2-(4-Fluoro-phenyl)-1-[1-(4-phenyl-butyl)-piperidin-4-yl]-ethanol::CHEMBL136622 D(2) dopamine receptor 900 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10089567 103916577 CHEMBL136622 ZINC13730003 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762019 C(COC1CCN(Cc2ccccc2)CC1)Cc1ccccc1 InChI=1S/C21H27NO/c1-3-8-19(9-4-1)12-7-17-23-21-13-15-22(16-14-21)18-20-10-5-2-6-11-20/h1-6,8-11,21H,7,12-18H2 OVLUKWRGJXXOHA-UHFFFAOYSA-N 50002275 1-Benzyl-4-(3-phenyl-propoxy)-piperidine; compound with but-2-enedioic acid::CHEMBL136642 D(2) dopamine receptor 8100 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002275&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10448066 103916581 CHEMBL136642 ZINC13730141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762020 Clc1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C17H22ClNO/c18-16-5-3-15(4-6-16)17(20)11-13-7-9-19(10-8-13)12-14-1-2-14/h3-6,13-14H,1-2,7-12H2 LJRYGMQGFOOAQO-UHFFFAOYSA-N 50002279 1-(4-Chloro-phenyl)-2-(1-cyclopropylmethyl-piperidin-4-yl)-ethanone; hydrobromide::CHEMBL544614 D(2) dopamine receptor 2004 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10429392 103916585 CHEMBL544614 ZINC00013937 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762022 OC(Cc1ccccc1)C1CCN(Cc2ccccc2)CC1 InChI=1S/C20H25NO/c22-20(15-17-7-3-1-4-8-17)19-11-13-21(14-12-19)16-18-9-5-2-6-10-18/h1-10,19-20,22H,11-16H2 IXJFAZPPIDOJGE-UHFFFAOYSA-N 50002300 1-(1-Benzyl-piperidin-4-yl)-2-phenyl-ethanol; hydrochloride::CHEMBL544375 D(2) dopamine receptor 8300 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10088108 103916606 CHEMBL544375 ZINC13729991 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762024 OC(CC1CCN(Cc2ccccc2)CC1)c1ccc2ccccc2c1 InChI=1S/C24H27NO/c26-24(23-11-10-21-8-4-5-9-22(21)17-23)16-19-12-14-25(15-13-19)18-20-6-2-1-3-7-20/h1-11,17,19,24,26H,12-16,18H2 AXUFIAPYKHZLJF-UHFFFAOYSA-N 50002270 2-(1-Benzyl-piperidin-4-yl)-1-naphthalen-2-yl-ethanol;0.25hydrate::CHEMBL137250 D(2) dopamine receptor 3329 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002270&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043199 103916576 CHEMBL137250 ZINC13730170 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762027 O=C(CC1CCN(CC2CC2)CC1)c1ccc(cc1)C#N InChI=1S/C18H22N2O/c19-12-15-3-5-17(6-4-15)18(21)11-14-7-9-20(10-8-14)13-16-1-2-16/h3-6,14,16H,1-2,7-11,13H2 PEWGDLTXNPKKLN-UHFFFAOYSA-N 50002245 4-[2-(1-Cyclopropylmethyl-piperidin-4-yl)-acetyl]-benzonitrile; compound with but-2-enedioic acid::CHEMBL130356::CHEMBL137776 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9795762 103916551 CHEMBL137776CHEMBL130356 ZINC00005428 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762028 CSc1ccc(cc1)C(O)CC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H27NOS/c1-24-20-9-7-19(8-10-20)21(23)15-17-11-13-22(14-12-17)16-18-5-3-2-4-6-18/h2-10,17,21,23H,11-16H2,1H3 KTYAFUISADDFOQ-UHFFFAOYSA-N 50002305 2-(1-Benzyl-piperidin-4-yl)-1-(4-methylsulfanyl-phenyl)-ethanol::CHEMBL136594 D(2) dopamine receptor 7364 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10042965 103916611 CHEMBL136594 ZINC13729963 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762030 Fc1ccc(cc1)C(=O)CC1CCCN(Cc2ccccc2)C1 InChI=1S/C20H22FNO/c21-19-10-8-18(9-11-19)20(23)13-17-7-4-12-22(15-17)14-16-5-2-1-3-6-16/h1-3,5-6,8-11,17H,4,7,12-15H2 DIQOZLFXPKMDDS-UHFFFAOYSA-N 50002283 2-(1-Benzyl-piperidin-3-yl)-1-(4-fluoro-phenyl)-ethanone::CHEMBL136781 D(2) dopamine receptor 34 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9972752 103916589 CHEMBL136781 ZINC27441638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762037 N#Cc1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C17H22N2O/c18-11-14-3-5-17(6-4-14)20-13-16-7-9-19(10-8-16)12-15-1-2-15/h3-6,15-16H,1-2,7-10,12-13H2 IOFBNVAOCHKHPO-UHFFFAOYSA-N 50002257 4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-benzonitrile::CHEMBL46463 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11777930 103916563 CHEMBL46463 ZINC13730045 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50762040 CC(O)c1ccc(OCC2CCN(CC3CC3)CC2)cc1 InChI=1S/C18H27NO2/c1-14(20)17-4-6-18(7-5-17)21-13-16-8-10-19(11-9-16)12-15-2-3-15/h4-7,14-16,20H,2-3,8-13H2,1H3 GTKCLGFNNRQQBP-UHFFFAOYSA-N 50002308 1-[4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-phenyl]-ethanol::CHEMBL136702 D(2) dopamine receptor >10000 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002308&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10085583 103916614 CHEMBL136702 ZINC13730027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761985 C(COCC1CCN(Cc2ccccc2)CC1)Cc1ccccc1 InChI=1S/C22H29NO/c1-3-8-20(9-4-1)12-7-17-24-19-22-13-15-23(16-14-22)18-21-10-5-2-6-11-21/h1-6,8-11,22H,7,12-19H2 CSHFTPUNJFOMTD-UHFFFAOYSA-N 50002268 1-Benzyl-4-(3-phenyl-propoxymethyl)-piperidine; compound with but-2-enedioic acid::CHEMBL337810::CHEMBL80656 D(2) dopamine receptor 839 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10426373 103916574 CHEMBL80656CHEMBL337810 ZINC13730144 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9 50761986 Fc1ccc(CN2CCC(COc3ccc(F)cc3)CC2)cc1 InChI=1S/C19H21F2NO/c20-17-3-1-15(2-4-17)13-22-11-9-16(10-12-22)14-23-19-7-5-18(21)6-8-19/h1-8,16H,9-14H2 PYTWTUIMYMLYEF-UHFFFAOYSA-N 50002269 1-(4-Fluoro-benzyl)-4-(4-fluoro-phenoxymethyl)-piperidine::CHEMBL136835 D(2) dopamine receptor 1070 ChEMBL 10.1021/jm00101a012 10.7270/Q28P614G 1360026 Gilligan, PJ; Cain, GA; Christos, TE; Cook, L; Drummond, S; Johnson, AL; Kergaye, AA; McElroy, JF; Rohrbach, KW; Schmidt, WK DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=7891&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002269&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425960 103916575 CHEMBL136835 ZINC00014949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS,7JVR,8IRS D(2) dopamine receptor DRD2_MOUSE P61168 P13953 Q0VGH9