BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
322590	CCOc1ccc(\C=C2/SC(=S)N(CCN)C2=O)cc1	InChI=1S/C14H16N2O2S2/c1-2-18-11-5-3-10(4-6-11)9-12-13(17)16(8-7-15)14(19)20-12/h3-6,9H,2,7-8,15H2,1H3/b12-9-	GYJTUKQKGFMUTI-XFXZXTDPSA-N	176672	US9115122, 76	Mitogen-activated protein kinase 1 [T157A]				 6100						US Patent		10.7270/Q2ZW1JP7		aid1801536	US9115122	Shapiro, PS; MacKerell, Jr., AD; Fletcher, S	University of Maryland, Baltimore	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=176672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=66&target=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=176672&enzyme=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search			71697073	313044404							1	MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNATCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS	2ZOQ,4QTB,6GES,7E73,7E75	Mitogen-activated protein kinase 1	MK01_MOUSE	P63085	P27703 Q3V1U6						
322591	NCCN1C(=S)S\C(=C/C=C/c2ccccc2)C1=O	InChI=1S/C14H14N2OS2/c15-9-10-16-13(17)12(19-14(16)18)8-4-7-11-5-2-1-3-6-11/h1-8H,9-10,15H2/b7-4+,12-8-	LTNMFFICGCDWIR-JHLWKMQHSA-N	176673	US9115122, 76.2	Mitogen-activated protein kinase 1 [T157A]				 2400						US Patent		10.7270/Q2ZW1JP7		aid1801536	US9115122	Shapiro, PS; MacKerell, Jr., AD; Fletcher, S	University of Maryland, Baltimore	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=176673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=66&target=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=176673&enzyme=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search			118986977	313044405							1	MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNATCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS	2ZOQ,4QTB,6GES,7E73,7E75	Mitogen-activated protein kinase 1	MK01_MOUSE	P63085	P27703 Q3V1U6						
322592	NCCN1C(=S)S\C(=C/c2ccc3OCOc3c2)C1=O	InChI=1S/C13H12N2O3S2/c14-3-4-15-12(16)11(20-13(15)19)6-8-1-2-9-10(5-8)18-7-17-9/h1-2,5-6H,3-4,7,14H2/b11-6-	BUBDMZSKWQUTPR-WDZFZDKYSA-N	176674	US9115122, 76.3	Mitogen-activated protein kinase 1 [T157A]				 8100						US Patent		10.7270/Q2ZW1JP7		aid1801536	US9115122	Shapiro, PS; MacKerell, Jr., AD; Fletcher, S	University of Maryland, Baltimore	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=176674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=66&target=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=176674&enzyme=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search			96869421	313044406							1	MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNATCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS	2ZOQ,4QTB,6GES,7E73,7E75	Mitogen-activated protein kinase 1	MK01_MOUSE	P63085	P27703 Q3V1U6						
322593	COc1ccc(\C=C2/SC(=S)N(CCN)C2=O)cc1OC	InChI=1S/C14H16N2O3S2/c1-18-10-4-3-9(7-11(10)19-2)8-12-13(17)16(6-5-15)14(20)21-12/h3-4,7-8H,5-6,15H2,1-2H3/b12-8-	URVWPCBRRQVMJC-WQLSENKSSA-N	176675	US9115122, 76.4	Mitogen-activated protein kinase 1 [T157A]				 3000						US Patent		10.7270/Q2ZW1JP7		aid1801536	US9115122	Shapiro, PS; MacKerell, Jr., AD; Fletcher, S	University of Maryland, Baltimore	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=176675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=66&target=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=176675&enzyme=Mitogen-activated+protein+kinase+1+%5BT157A%5D&column=ki&startPg=0&Increment=50&submit=Search			118986978	313044407							1	MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNATCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS	2ZOQ,4QTB,6GES,7E73,7E75	Mitogen-activated protein kinase 1	MK01_MOUSE	P63085	P27703 Q3V1U6