BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 188894 ONC=Nc1ccc(N2CCOCC2)c(Cl)c1 InChI=1S/C11H14ClN3O2/c12-10-7-9(13-8-14-16)1-2-11(10)15-3-5-17-6-4-15/h1-2,7-8,16H,3-6H2,(H,13,14) ZTXADXBIGLLOFX-UHFFFAOYSA-N 86694 N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyformamidine::TS-011 Prostaglandin G/H synthase 2 Ovis aries >10000 PDSP Ki 10.1124/jpet.105.083964 10.7270/Q2MW2FQQ 15831442 Miyata, N; Seki, T; Tanaka, Y; Omura, T; Taniguchi, K; Doi, M; Bandou, K; Kametani, S; Sato, M; Okuyama, S; Cambj-Sapunar, L; Harder, DR; Roman, RJ Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86694&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9816527 136352743 ZINC06746071 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252796 Cc1cc(=O)n([nH]1)-c1ccccc1 InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-7,11H,1H3 KZQYIMCESJLPQH-UHFFFAOYSA-N 38550 3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE::5-methyl-2-phenyl-1,2- dihydro-3H-pyrazol-3-one (3)::5-methyl-2-phenyl-2-pyrazolin-3-one::5-methyl-2-phenyl-4H-pyrazol-3-one::MLS000069602::SMR000059020::cid_4021 Prostaglandin G/H synthase 2 Ovis aries 3.500e+4 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38550&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70335 252619456 31530 ZINC18203737 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252797 Cc1[nH]n(-c2ccccc2)c(=O)c1CNC(N)=O InChI=1S/C12H14N4O2/c1-8-10(7-14-12(13)18)11(17)16(15-8)9-5-3-2-4-6-9/h2-6,15H,7H2,1H3,(H3,13,14,18) PVQMEVRMZBBUNY-UHFFFAOYSA-N 123788 1-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4- yl)methyl]urea (5a) Prostaglandin G/H synthase 2 Ovis aries 2.30e+3 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123788&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766198 225150197 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252798 Cc1[nH]n(-c2ccccc2)c(=O)c1CNC(=O)Nc1ccc(Cl)cc1 InChI=1S/C18H17ClN4O2/c1-12-16(17(24)23(22-12)15-5-3-2-4-6-15)11-20-18(25)21-14-9-7-13(19)8-10-14/h2-10,22H,11H2,1H3,(H2,20,21,25) DNVBOLXJRPAFJX-UHFFFAOYSA-N 123789 1-(4-chlorophenyl)-3-[(3-methyl-5-oxo-1-phenyl-4,5- dihydro-1H-pyrazol-4-yl) methyl]urea (5b) Prostaglandin G/H synthase 2 Ovis aries >1.00e+5 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123789&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766199 225150198 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252799 Cc1[nH]n(-c2ccccc2)c(=O)c1CNC(N)=S InChI=1S/C12H14N4OS/c1-8-10(7-14-12(13)18)11(17)16(15-8)9-5-3-2-4-6-9/h2-6,15H,7H2,1H3,(H3,13,14,18) WHFLNDJJRUEOBD-UHFFFAOYSA-N 123790 1-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4- yl)methyl]thiourea (5c) Prostaglandin G/H synthase 2 Ovis aries 8.500e+4 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123790&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766200 225150199 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252800 Cc1[nH]n(-c2ccccc2)c(=O)c1CNC(=S)Nc1ccccc1 InChI=1S/C18H18N4OS/c1-13-16(12-19-18(24)20-14-8-4-2-5-9-14)17(23)22(21-13)15-10-6-3-7-11-15/h2-11,21H,12H2,1H3,(H2,19,20,24) CLWNURLBTVRFAA-UHFFFAOYSA-N 123791 1-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4- yl)methyl]-3-phenylthiourea (5d) Prostaglandin G/H synthase 2 Ovis aries 2.0e+2 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123791&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766201 225150200 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252801 Cc1[nH]n(-c2ccccc2)c(=O)c1CN=C(N)N InChI=1S/C12H15N5O/c1-8-10(7-15-12(13)14)11(18)17(16-8)9-5-3-2-4-6-9/h2-6,16H,7H2,1H3,(H4,13,14,15) WHMRCHFLLHSMQZ-UHFFFAOYSA-N 123792 1-((3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4- yl)methyl)guanidine (5e) Prostaglandin G/H synthase 2 Ovis aries 5.070e+4 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123792&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766202 225150201 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252802 Cc1[nH]n(-c2ccccc2)c(=O)c1CNc1ccc(cc1)S(N)(=O)=O InChI=1S/C17H18N4O3S/c1-12-16(17(22)21(20-12)14-5-3-2-4-6-14)11-19-13-7-9-15(10-8-13)25(18,23)24/h2-10,19-20H,11H2,1H3,(H2,18,23,24) DNGVGHPGBVVYBV-UHFFFAOYSA-N 123793 4-{[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol- 4-yl)methyl]amino} benzene sulfonamide (5f) Prostaglandin G/H synthase 2 Ovis aries 1.00e+3 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123793&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766203 225150202 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252803 Cc1[nH]n(-c2ccccc2)c(=O)c1CNC(=O)NN InChI=1S/C12H15N5O2/c1-8-10(7-14-12(19)15-13)11(18)17(16-8)9-5-3-2-4-6-9/h2-6,16H,7,13H2,1H3,(H2,14,15,19) YAQKPFAJZKTAAS-UHFFFAOYSA-N 123794 N-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol- 4yl)methyl] hydrazine carboxamide (5g) Prostaglandin G/H synthase 2 Ovis aries >1.00e+5 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123794&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766204 225150203 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252804 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 4.0e+2 37.00 C Curated from the literature by BindingDB 10.1111/cbdd.12324 10.7270/Q24M937V 24636540 aid1800496 Dube, PN; Bule, SS; Mokale, SN; Kumbhare, MR; Dighe, PR; Ushir, YV Y.B. Chavan College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252818 NNCC(=O)Nc1ccc(cc1)S(N)(=O)=O InChI=1S/C8H12N4O3S/c9-11-5-8(13)12-6-1-3-7(4-2-6)16(10,14)15/h1-4,11H,5,9H2,(H,12,13)(H2,10,14,15) MVRAZXITQGPJKT-UHFFFAOYSA-N 123795 2-Hydrazinyl-N-(4-sulfamoylphenyl)acetamide (3) Prostaglandin G/H synthase 2 Ovis aries 2.12e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123795&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766205 225150204 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252819 NS(=O)(=O)c1ccc(NC(=O)CN=NCc2ccccc2)cc1 InChI=1S/C15H16N4O3S/c16-23(21,22)14-8-6-13(7-9-14)19-15(20)11-18-17-10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,19,20)(H2,16,21,22) BVLMTOLUWQLBMM-UHFFFAOYSA-N 123796 2-(2-Benzylidenehydrazinyl)-N-(4-sulfamoylphenyl) acetamide (4) Prostaglandin G/H synthase 2 Ovis aries 3.51e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123796&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766206 225150205 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252820 NS(=O)(=O)c1ccc(NC(=O)CN=NCc2ccccc2F)cc1 InChI=1S/C15H15FN4O3S/c16-14-4-2-1-3-11(14)9-18-19-10-15(21)20-12-5-7-13(8-6-12)24(17,22)23/h1-8H,9-10H2,(H,20,21)(H2,17,22,23) QYOQQACKOHAPTB-UHFFFAOYSA-N 123797 2-(2-(2-Fluorobenzylidene)hydrazinyl)-N-(4- sulfamoylphenyl)acetamide (5) Prostaglandin G/H synthase 2 Ovis aries 5.68e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123797&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766207 225150206 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252821 CN(C)c1ccc(CN=NCC(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1 InChI=1S/C17H21N5O3S/c1-22(2)15-7-3-13(4-8-15)11-19-20-12-17(23)21-14-5-9-16(10-6-14)26(18,24)25/h3-10H,11-12H2,1-2H3,(H,21,23)(H2,18,24,25) OMKWYPIVDAOGDB-UHFFFAOYSA-N 123800 2-(2-(4-(Dimethylamino)benzylidene)hydrazinyl)-N- (4-sulfamoylphenyl)acetamide (8) Prostaglandin G/H synthase 2 Ovis aries 2.26e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123800&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766208 225150207 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252822 NS(=O)(=O)c1ccc(NC(=O)CN=NCc2ccc(F)cc2)cc1 InChI=1S/C15H15FN4O3S/c16-12-3-1-11(2-4-12)9-18-19-10-15(21)20-13-5-7-14(8-6-13)24(17,22)23/h1-8H,9-10H2,(H,20,21)(H2,17,22,23) DILMZFPPZQYXFZ-UHFFFAOYSA-N 123801 2-(2-(4-Fluorobenzylidene)hydrazinyl)-N-(4- sulfamoylphenyl)acetamide (9) Prostaglandin G/H synthase 2 Ovis aries 1.73e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123801&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766209 225150208 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252823 COc1ccc(CN=NCC(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1 InChI=1S/C16H18N4O4S/c1-24-14-6-2-12(3-7-14)10-18-19-11-16(21)20-13-4-8-15(9-5-13)25(17,22)23/h2-9H,10-11H2,1H3,(H,20,21)(H2,17,22,23) VRBUINXSTYZOHX-UHFFFAOYSA-N 123802 2-(2-(4-Methoxybenzylidene)hydrazinyl)-N-(4- sulfamoylphenyl)acetamide (10) Prostaglandin G/H synthase 2 Ovis aries 2.65e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123802&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766210 225150209 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252824 NS(=O)(=O)c1ccc(NC(=O)Cn2nc(cc2-c2ccccc2F)-c2ccccc2)cc1 InChI=1S/C23H19FN4O3S/c24-20-9-5-4-8-19(20)22-14-21(16-6-2-1-3-7-16)27-28(22)15-23(29)26-17-10-12-18(13-11-17)32(25,30)31/h1-14H,15H2,(H,26,29)(H2,25,30,31) SPJGCSMEMWLORY-UHFFFAOYSA-N 123804 2-(5-(2-Fluorophenyl)-3-phenyl-1H-pyrazol-1-yl)-N- (4-sulfamoylphenyl)acetamide (12) Prostaglandin G/H synthase 2 Ovis aries 3.64e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123804&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766211 225150210 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252825 NS(=O)(=O)c1ccc(NC(=O)Cn2nc(cc2-c2ccc(Br)cc2)-c2ccccc2)cc1 InChI=1S/C23H19BrN4O3S/c24-18-8-6-17(7-9-18)22-14-21(16-4-2-1-3-5-16)27-28(22)15-23(29)26-19-10-12-20(13-11-19)32(25,30)31/h1-14H,15H2,(H,26,29)(H2,25,30,31) XFRGIMBLVICGOM-UHFFFAOYSA-N 123805 2-(5-(4-Bromophenyl)-3-phenyl-1H-pyrazol-1-yl)-N- (4-sulfamoylphenyl)acetamide (13) Prostaglandin G/H synthase 2 Ovis aries 2.46e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123805&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766212 225150211 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252826 NS(=O)(=O)c1ccc(NC(=O)Cn2nc(cc2-c2ccc(Cl)cc2)-c2ccccc2)cc1 InChI=1S/C23H19ClN4O3S/c24-18-8-6-17(7-9-18)22-14-21(16-4-2-1-3-5-16)27-28(22)15-23(29)26-19-10-12-20(13-11-19)32(25,30)31/h1-14H,15H2,(H,26,29)(H2,25,30,31) LKUITMGIUAIXSR-UHFFFAOYSA-N 123806 2-(5-(4-Chlorophenyl)-3-phenyl-1H-pyrazol-1-yl)-N- (4-sulfamoylphenyl)acetamide (14) Prostaglandin G/H synthase 2 Ovis aries 1.174e+4 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123806&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766213 225150212 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252827 CN(C)c1ccc(cc1)-c1cc(nn1CC(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 InChI=1S/C25H25N5O3S/c1-29(2)21-12-8-19(9-13-21)24-16-23(18-6-4-3-5-7-18)28-30(24)17-25(31)27-20-10-14-22(15-11-20)34(26,32)33/h3-16H,17H2,1-2H3,(H,27,31)(H2,26,32,33) NRMRHFBJZXWBMC-UHFFFAOYSA-N 123807 2-(5-(4-(Dimethylamino)phenyl)-3-phenyl-1Hpyrazol- 1-yl)-N-(4-sulfamoylphenyl)acetamide (15) Prostaglandin G/H synthase 2 Ovis aries 1.68e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123807&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766214 225150213 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252828 NS(=O)(=O)c1ccc(NC(=O)Cn2nc(cc2-c2ccc(F)cc2)-c2ccccc2)cc1 InChI=1S/C23H19FN4O3S/c24-18-8-6-17(7-9-18)22-14-21(16-4-2-1-3-5-16)27-28(22)15-23(29)26-19-10-12-20(13-11-19)32(25,30)31/h1-14H,15H2,(H,26,29)(H2,25,30,31) RLKQSVPJMFNUTQ-UHFFFAOYSA-N 123808 2-(5-(4-Fluorophenyl)-3-phenyl-1H-pyrazol-1-yl)-N- (4-sulfamoylphenyl)acetamide (16) Prostaglandin G/H synthase 2 Ovis aries 2.22e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123808&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766215 225150214 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252829 COc1ccc(cc1)-c1cc(nn1CC(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 InChI=1S/C24H22N4O4S/c1-32-20-11-7-18(8-12-20)23-15-22(17-5-3-2-4-6-17)27-28(23)16-24(29)26-19-9-13-21(14-10-19)33(25,30)31/h2-15H,16H2,1H3,(H,26,29)(H2,25,30,31) QNTMPOMWOURVRJ-UHFFFAOYSA-N 123809 2-(5-(4-Methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl)- N-(4-sulfamoylphenyl)acetamide (17) Prostaglandin G/H synthase 2 Ovis aries 1.76e+3 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123809&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766216 225150215 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 252830 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 2.2e+2 8 25.00 C Curated from the literature by BindingDB 10.1111/cbdd.12336 10.7270/Q20V8BGP 24720475 aid1800497 Mohammed, KO; Nissan, YM Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312450 COc1cc(cc(OC)c1OC)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccc(Br)cc1 InChI=1S/C24H24BrN3O5S/c1-31-22-12-16(13-23(32-2)24(22)33-3)21-14-20(15-4-6-17(25)7-5-15)27-28(21)18-8-10-19(11-9-18)34(26,29)30/h4-13,21H,14H2,1-3H3,(H2,26,29,30) DOSNORRGQWDFAU-UHFFFAOYSA-N 221997 4-[3-(4-Bromo-phenyl)-5-(3,4,5-trimethoxy-phenyl)-4,5-dihydropyrazol- 1-yl]-benzene-sulfonamide (10a) Prostaglandin G/H synthase 2 Ovis aries 780 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221997&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842555 335960867 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312451 COc1cc(cc(OC)c1OC)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccc(Cl)cc1 InChI=1S/C24H24ClN3O5S/c1-31-22-12-16(13-23(32-2)24(22)33-3)21-14-20(15-4-6-17(25)7-5-15)27-28(21)18-8-10-19(11-9-18)34(26,29)30/h4-13,21H,14H2,1-3H3,(H2,26,29,30) YLPUZAVOIIKMGY-UHFFFAOYSA-N 221998 4-[3-(4-Chloro-phenyl)-5-(3,4,5-trimethoxy-phenyl)-4,5-dihydropyrazol-1-yl]-benzene-sulfonamide (10b) Prostaglandin G/H synthase 2 Ovis aries 220 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221998&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842556 335960868 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312452 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(Cl)cc1)c1ccc(Br)cc1 InChI=1S/C21H17BrClN3O2S/c22-16-5-1-14(2-6-16)20-13-21(15-3-7-17(23)8-4-15)26(25-20)18-9-11-19(12-10-18)29(24,27)28/h1-12,21H,13H2,(H2,24,27,28) HXPOPQBBDVWDGK-UHFFFAOYSA-N 221999 4-[3-(4-Bromo-phenyl)-5-(4-chloro-phenyl)-4,5-dihydro-pyrazol-1-yl]-benzene-sulfonamide (10c) Prostaglandin G/H synthase 2 Ovis aries 1430 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=221999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=221999&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842557 335960869 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312453 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(Cl)cc1)c1ccc(Cl)cc1 InChI=1S/C21H17Cl2N3O2S/c22-16-5-1-14(2-6-16)20-13-21(15-3-7-17(23)8-4-15)26(25-20)18-9-11-19(12-10-18)29(24,27)28/h1-12,21H,13H2,(H2,24,27,28) LNFLLBNNTOBDSM-UHFFFAOYSA-N 222000 4-[3-(4-Chloro-phenyl)-5-(4-chloro-phenyl)-4,5-dihydro-pyrazol-1-yl]-benzene-sulfonamide (10d) Prostaglandin G/H synthase 2 Ovis aries 900 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222000&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842558 335960870 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312454 COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccc(Br)cc1 InChI=1S/C22H20BrN3O3S/c1-29-19-10-4-16(5-11-19)22-14-21(15-2-6-17(23)7-3-15)25-26(22)18-8-12-20(13-9-18)30(24,27)28/h2-13,22H,14H2,1H3,(H2,24,27,28) OXUHCJQIOSTMPK-UHFFFAOYSA-N 54643 4-[3-(4-Bromo-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydropyrazol-1-yl]-benzene-sulfonamide (10e)::4-[3-(4-bromophenyl)-5-(4-methoxyphenyl)-2-pyrazolin-1-yl]benzenesulfonamide::4-[5-(4-bromophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide::KUC103396N::UNM-0000306138::cid_44143697 Prostaglandin G/H synthase 2 Ovis aries 630 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54643&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44143697 252634669 ZINC70459608 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312455 COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccc(Cl)cc1 InChI=1S/C22H20ClN3O3S/c1-29-19-10-4-16(5-11-19)22-14-21(15-2-6-17(23)7-3-15)25-26(22)18-8-12-20(13-9-18)30(24,27)28/h2-13,22H,14H2,1H3,(H2,24,27,28) QRIHFWVYVVPTKX-UHFFFAOYSA-N 54640 4-[3-(4-Chloro-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydropyrazol-1-yl]-benzene-sulfonamide (10f)::4-[3-(4-chlorophenyl)-5-(4-methoxyphenyl)-2-pyrazolin-1-yl]benzenesulfonamide::4-[5-(4-chlorophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide::KUC103415N::UNM-0000306132::cid_42628051 Prostaglandin G/H synthase 2 Ovis aries 740 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54640&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42628051 252634666 ZINC61958733 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312456 COc1cc(cc(OC)c1OC)C1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1ccc(Br)cc1 InChI=1S/C25H25BrN2O5S/c1-31-23-13-17(14-24(32-2)25(23)33-3)22-15-21(16-5-7-18(26)8-6-16)27-28(22)19-9-11-20(12-10-19)34(4,29)30/h5-14,22H,15H2,1-4H3 KQSQZUXVXNCFTJ-UHFFFAOYSA-N 222001 3-(4-Bromo-phenyl)-1-(4-methanesulfonyl-phenyl)-5-(3,4,5-trimethoxy-phenyl)-4,5-dihydro-1H-pyrazole (10g) Prostaglandin G/H synthase 2 Ovis aries 980 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222001&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842559 335960871 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312457 COc1cc(cc(OC)c1OC)C1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1ccc(Cl)cc1 InChI=1S/C25H25ClN2O5S/c1-31-23-13-17(14-24(32-2)25(23)33-3)22-15-21(16-5-7-18(26)8-6-16)27-28(22)19-9-11-20(12-10-19)34(4,29)30/h5-14,22H,15H2,1-4H3 ZTMFEJRAAKDUFH-UHFFFAOYSA-N 222002 3-(4-Bromo-phenyl)-5-(4-chloro-phenyl)-1-(4-methanesulfonylphenyl)-4,5-dihydro-1H-pyrazole (10i)::3-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-5-(3,4,5-trimethoxy-phenyl)-4,5-dihydro-1H-pyrazole (10h) Prostaglandin G/H synthase 2 Ovis aries 420 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222002&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842560 335960872 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312458 COc1cc(cc(OC)c1OC)C1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1ccc(Cl)cc1 InChI=1S/C25H25ClN2O5S/c1-31-23-13-17(14-24(32-2)25(23)33-3)22-15-21(16-5-7-18(26)8-6-16)27-28(22)19-9-11-20(12-10-19)34(4,29)30/h5-14,22H,15H2,1-4H3 ZTMFEJRAAKDUFH-UHFFFAOYSA-N 222002 3-(4-Bromo-phenyl)-5-(4-chloro-phenyl)-1-(4-methanesulfonylphenyl)-4,5-dihydro-1H-pyrazole (10i)::3-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-5-(3,4,5-trimethoxy-phenyl)-4,5-dihydro-1H-pyrazole (10h) Prostaglandin G/H synthase 2 Ovis aries 2980 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222002&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842560 335960872 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312459 CS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(Cl)cc1)c1ccc(Cl)cc1 InChI=1S/C22H18Cl2N2O2S/c1-29(27,28)20-12-10-19(11-13-20)26-22(16-4-8-18(24)9-5-16)14-21(25-26)15-2-6-17(23)7-3-15/h2-13,22H,14H2,1H3 XOVUEUILNCXCPG-UHFFFAOYSA-N 222004 3,5-Bis-(4-chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4,5-dihydro-1H-pyrazole (10j) Prostaglandin G/H synthase 2 Ovis aries 1520 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222004&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842561 335960873 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312460 COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1ccc(Br)cc1 InChI=1S/C23H21BrN2O3S/c1-29-20-11-5-17(6-12-20)23-15-22(16-3-7-18(24)8-4-16)25-26(23)19-9-13-21(14-10-19)30(2,27)28/h3-14,23H,15H2,1-2H3 WHKVOHPPRYWKLJ-UHFFFAOYSA-N 222005 3-(4-Bromo-phenyl)-1-(4-methanesulfonyl-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazole (10k) Prostaglandin G/H synthase 2 Ovis aries 630 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222005&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842562 335960874 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312461 COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1ccc(Cl)cc1 InChI=1S/C23H21ClN2O3S/c1-29-20-11-5-17(6-12-20)23-15-22(16-3-7-18(24)8-4-16)25-26(23)19-9-13-21(14-10-19)30(2,27)28/h3-14,23H,15H2,1-2H3 ZZIXESRYXAIDNW-UHFFFAOYSA-N 222006 3-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazole (10l) Prostaglandin G/H synthase 2 Ovis aries 3410 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222006&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842563 335960875 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 312462 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 840 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.11.008 10.7270/Q2WH2NVP 27894776 aid1802571 Abdellatif, KR; Fadaly, WA Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351733 COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C25H20N6O3/c1-33-20-14-12-19(13-15-20)26-24-29-28-21(34-24)16-31-25(32)27-22(17-8-4-2-5-9-17)23(30-31)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,26,29) STOZTMZCUWJXDR-UHFFFAOYSA-N 198171 2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3c) Prostaglandin G/H synthase 2 Ovis aries 7.7e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198171&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198619 318489243 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351734 Clc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C24H17ClN6O2/c25-18-11-13-19(14-12-18)26-23-29-28-20(33-23)15-31-24(32)27-21(16-7-3-1-4-8-16)22(30-31)17-9-5-2-6-10-17/h1-14H,15H2,(H,26,29) UWWQNKCREVHKKT-UHFFFAOYSA-N 198172 2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3d) Prostaglandin G/H synthase 2 Ovis aries 6.5e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198172&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198620 318489244 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351735 [O-][N+](=O)c1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C24H17N7O4/c32-24-26-21(16-7-3-1-4-8-16)22(17-9-5-2-6-10-17)29-30(24)15-20-27-28-23(35-20)25-18-11-13-19(14-12-18)31(33)34/h1-14H,15H2,(H,25,28) SIIQMKKTVDYUCD-UHFFFAOYSA-N 198173 2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3e) Prostaglandin G/H synthase 2 Ovis aries 6.0e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198173&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198621 318489245 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351736 COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1 InChI=1S/C25H20N6O2S/c1-33-20-14-12-19(13-15-20)26-24-29-28-21(34-24)16-31-25(32)27-22(17-8-4-2-5-9-17)23(30-31)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,26,29) RUFINCLRAHCHCC-UHFFFAOYSA-N 198174 2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4c) Prostaglandin G/H synthase 2 Ovis aries 9.0e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198174&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198622 318489246 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351737 Clc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1 InChI=1S/C24H17ClN6OS/c25-18-11-13-19(14-12-18)26-23-29-28-20(33-23)15-31-24(32)27-21(16-7-3-1-4-8-16)22(30-31)17-9-5-2-6-10-17/h1-14H,15H2,(H,26,29) NIWSMJIVUFQTSU-UHFFFAOYSA-N 198175 2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4d) Prostaglandin G/H synthase 2 Ovis aries 1.11e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198175&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198623 318489247 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351738 [O-][N+](=O)c1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1 InChI=1S/C24H17N7O3S/c32-24-26-21(16-7-3-1-4-8-16)22(17-9-5-2-6-10-17)29-30(24)15-20-27-28-23(35-20)25-18-11-13-19(14-12-18)31(33)34/h1-14H,15H2,(H,25,28) WIWJJBQZCRGOAL-UHFFFAOYSA-N 198176 2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4e) Prostaglandin G/H synthase 2 Ovis aries 1.01e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198176&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198624 318489248 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351739 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 3.67e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351740 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 5.4e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802056 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351741 COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C25H20N6O3/c1-33-20-14-12-19(13-15-20)26-24-29-28-21(34-24)16-31-25(32)27-22(17-8-4-2-5-9-17)23(30-31)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,26,29) STOZTMZCUWJXDR-UHFFFAOYSA-N 198171 2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3c) Prostaglandin G/H synthase 2 Ovis aries 6.5e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802057 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198171&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198619 318489243 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351742 Clc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C24H17ClN6O2/c25-18-11-13-19(14-12-18)26-23-29-28-20(33-23)15-31-24(32)27-21(16-7-3-1-4-8-16)22(30-31)17-9-5-2-6-10-17/h1-14H,15H2,(H,26,29) UWWQNKCREVHKKT-UHFFFAOYSA-N 198172 2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3d) Prostaglandin G/H synthase 2 Ovis aries 6.3e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802057 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198172&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198620 318489244 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351743 [O-][N+](=O)c1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C24H17N7O4/c32-24-26-21(16-7-3-1-4-8-16)22(17-9-5-2-6-10-17)29-30(24)15-20-27-28-23(35-20)25-18-11-13-19(14-12-18)31(33)34/h1-14H,15H2,(H,25,28) SIIQMKKTVDYUCD-UHFFFAOYSA-N 198173 2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3e) Prostaglandin G/H synthase 2 Ovis aries 5.0e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802057 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198173&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198621 318489245 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351744 COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1 InChI=1S/C25H20N6O2S/c1-33-20-14-12-19(13-15-20)26-24-29-28-21(34-24)16-31-25(32)27-22(17-8-4-2-5-9-17)23(30-31)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,26,29) RUFINCLRAHCHCC-UHFFFAOYSA-N 198174 2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4c) Prostaglandin G/H synthase 2 Ovis aries 7.7e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802057 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198174&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198622 318489246 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351745 Clc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1 InChI=1S/C24H17ClN6OS/c25-18-11-13-19(14-12-18)26-23-29-28-20(33-23)15-31-24(32)27-21(16-7-3-1-4-8-16)22(30-31)17-9-5-2-6-10-17/h1-14H,15H2,(H,26,29) NIWSMJIVUFQTSU-UHFFFAOYSA-N 198175 2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4d) Prostaglandin G/H synthase 2 Ovis aries 9.6e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802057 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198175&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198623 318489247 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351746 [O-][N+](=O)c1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)s2)cc1 InChI=1S/C24H17N7O3S/c32-24-26-21(16-7-3-1-4-8-16)22(17-9-5-2-6-10-17)29-30(24)15-20-27-28-23(35-20)25-18-11-13-19(14-12-18)31(33)34/h1-14H,15H2,(H,25,28) WIWJJBQZCRGOAL-UHFFFAOYSA-N 198176 2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (4e) Prostaglandin G/H synthase 2 Ovis aries 8.8e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802057 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198176&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198624 318489248 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 351747 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 4.9e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.10.003 10.7270/Q2SB44K0 27750057 aid1802057 Banerjee, AG; Das, N; Shengule, SA; Sharma, PA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388630 [O-][N+](=O)c1ccc(cc1)-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1 InChI=1S/C18H11N3O3/c19-11-16-15(12-4-2-1-3-5-12)10-17(20-18(16)22)13-6-8-14(9-7-13)21(23)24/h1-10H,(H,20,22) IWYDXMMUXOKMRE-UHFFFAOYSA-N 222079 6-(4-nitrophenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (4a) Prostaglandin G/H synthase 2 Ovis aries 3.8e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222079&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842635 335960948 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388631 Cc1ccc(cc1)-c1cc([nH]c(=O)c1C#N)-c1ccc(cc1)[N+]([O-])=O InChI=1S/C19H13N3O3/c1-12-2-4-13(5-3-12)16-10-18(21-19(23)17(16)11-20)14-6-8-15(9-7-14)22(24)25/h2-10H,1H3,(H,21,23) KAOKONAXWPUKKX-UHFFFAOYSA-N 222080 6-(4-Nitrophenyl)-2-oxo-4-(p-tolyl)-1,2-dihydropyridine-3-carbonitrile (4b) Prostaglandin G/H synthase 2 Ovis aries 2.9e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222080&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842636 335960949 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388632 [O-][N+](=O)c1ccc(cc1)-c1cc(-c2ccc(Cl)cc2)c(C#N)c(=O)[nH]1 InChI=1S/C18H10ClN3O3/c19-13-5-1-11(2-6-13)15-9-17(21-18(23)16(15)10-20)12-3-7-14(8-4-12)22(24)25/h1-9H,(H,21,23) IBVFNOVHMFCXSZ-UHFFFAOYSA-N 222081 4-(4-chlorophenyl)-6-(4-nitrophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4c) Prostaglandin G/H synthase 2 Ovis aries 7.3e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222081&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842637 335960950 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388633 [O-][N+](=O)c1ccc(cc1)-c1cc(-c2ccc(F)cc2)c(C#N)c(=O)[nH]1 InChI=1S/C18H10FN3O3/c19-13-5-1-11(2-6-13)15-9-17(21-18(23)16(15)10-20)12-3-7-14(8-4-12)22(24)25/h1-9H,(H,21,23) KIVUYJDZGCXHKP-UHFFFAOYSA-N 222082 4-(4-Fluorophenyl)-6-(4-nitrophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4d) Prostaglandin G/H synthase 2 Ovis aries 4.6e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222082&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842638 335960951 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388634 [O-][N+](=O)c1ccc(cc1)-c1cc(-c2ccco2)c(C#N)c(=O)[nH]1 InChI=1S/C16H9N3O4/c17-9-13-12(15-2-1-7-23-15)8-14(18-16(13)20)10-3-5-11(6-4-10)19(21)22/h1-8H,(H,18,20) YEUOEHHTYFEKIC-UHFFFAOYSA-N 222083 4-(2-Furyl)-6-(4-nitrophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4e) Prostaglandin G/H synthase 2 Ovis aries 1.2e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222083&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842639 335960952 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388635 [O-][N+](=O)c1ccc(cc1)-c1cc(-c2cccs2)c(C#N)c(=O)[nH]1 InChI=1S/C16H9N3O3S/c17-9-13-12(15-2-1-7-23-15)8-14(18-16(13)20)10-3-5-11(6-4-10)19(21)22/h1-8H,(H,18,20) BEDMYRXWCCGKHO-UHFFFAOYSA-N 222084 6-(4-nitrophenyl)-2-oxo-4-(thiophen-2-yl)-1,2-dihydropyridine-3-carbonitrile (4f) Prostaglandin G/H synthase 2 Ovis aries 8.7e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222084&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 78293720 335960953 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388636 CC(C)Cc1ccc(cc1)-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1 InChI=1S/C22H20N2O/c1-15(2)12-16-8-10-18(11-9-16)21-13-19(17-6-4-3-5-7-17)20(14-23)22(25)24-21/h3-11,13,15H,12H2,1-2H3,(H,24,25) PGQADCGAZCNPFE-UHFFFAOYSA-N 222085 6-(4-Isobutylphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (4g) Prostaglandin G/H synthase 2 Ovis aries 3.4e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222085&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842640 335960954 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388637 CC(C)Cc1ccc(cc1)-c1cc(-c2ccc(C)cc2)c(C#N)c(=O)[nH]1 InChI=1S/C23H22N2O/c1-15(2)12-17-6-10-19(11-7-17)22-13-20(21(14-24)23(26)25-22)18-8-4-16(3)5-9-18/h4-11,13,15H,12H2,1-3H3,(H,25,26) KNTFGGMUYHTJKE-UHFFFAOYSA-N 222086 6-(4-Isobutylphenyl)-2-oxo-4-(p-tolyl)-1,2-dihydropyridine-3-carbonitrile (4h) Prostaglandin G/H synthase 2 Ovis aries 2.7e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222086&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842641 335960955 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388638 CC(C)Cc1ccc(cc1)-c1cc(-c2ccc(Cl)cc2)c(C#N)c(=O)[nH]1 InChI=1S/C22H19ClN2O/c1-14(2)11-15-3-5-17(6-4-15)21-12-19(20(13-24)22(26)25-21)16-7-9-18(23)10-8-16/h3-10,12,14H,11H2,1-2H3,(H,25,26) YBMPXPBQIYDROY-UHFFFAOYSA-N 222087 4-(4-Chlorophenyl)-6-(4-isobutylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4i) Prostaglandin G/H synthase 2 Ovis aries 5.1e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222087&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 78291682 335960956 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388639 CC(C)Cc1ccc(cc1)-c1cc(-c2ccc(F)cc2)c(C#N)c(=O)[nH]1 InChI=1S/C22H19FN2O/c1-14(2)11-15-3-5-17(6-4-15)21-12-19(20(13-24)22(26)25-21)16-7-9-18(23)10-8-16/h3-10,12,14H,11H2,1-2H3,(H,25,26) VUDFIJJEYQVMCP-UHFFFAOYSA-N 222088 4-(4-Fluorophenyl)-6-(4-isobutylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4j) Prostaglandin G/H synthase 2 Ovis aries 9.3e+2 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222088&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842642 335960957 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388640 CC(C)Cc1ccc(cc1)-c1cc(-c2ccco2)c(C#N)c(=O)[nH]1 InChI=1S/C20H18N2O2/c1-13(2)10-14-5-7-15(8-6-14)18-11-16(19-4-3-9-24-19)17(12-21)20(23)22-18/h3-9,11,13H,10H2,1-2H3,(H,22,23) QVGFXKYGHPCMFY-UHFFFAOYSA-N 222089 4-(2-Furyl)-6-(4-isobutylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4k) Prostaglandin G/H synthase 2 Ovis aries 1.11e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222089&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842643 335960958 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388641 CC(C)Cc1ccc(cc1)-c1cc(-c2cccs2)c(C#N)c(=O)[nH]1 InChI=1S/C20H18N2OS/c1-13(2)10-14-5-7-15(8-6-14)18-11-16(19-4-3-9-24-19)17(12-21)20(23)22-18/h3-9,11,13H,10H2,1-2H3,(H,22,23) OWZDSQFQTQRAOE-UHFFFAOYSA-N 222090 6-(4-Isobutylphenyl)-2-oxo-4-(2-thienyl)-1,2-dihydropyridine-3-carbonitrile (4l) Prostaglandin G/H synthase 2 Ovis aries 3.7e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222090&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842644 335960959 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388642 CS(=O)(=O)Nc1ccc(cc1)-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1 InChI=1S/C19H15N3O3S/c1-26(24,25)22-15-9-7-14(8-10-15)18-11-16(13-5-3-2-4-6-13)17(12-20)19(23)21-18/h2-11,22H,1H3,(H,21,23) JLMIMPVJQQTMEL-UHFFFAOYSA-N 222091 6-(4-Methanesulfonylaminophenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (4m) Prostaglandin G/H synthase 2 Ovis aries 1.6e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222091&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842645 335960960 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388643 Cc1ccc(cc1)-c1cc([nH]c(=O)c1C#N)-c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C20H17N3O3S/c1-13-3-5-14(6-4-13)17-11-19(22-20(24)18(17)12-21)15-7-9-16(10-8-15)23-27(2,25)26/h3-11,23H,1-2H3,(H,22,24) OHAZAMMTOXHBGM-UHFFFAOYSA-N 222092 6-(4-Methanesulfonylaminophenyl)-2-oxo-4-(4-tolyl)-1,2-dihydropyridine-3-carbonitrile (4n) Prostaglandin G/H synthase 2 Ovis aries 1.3e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222092&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842646 335960961 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388644 CS(=O)(=O)Nc1ccc(cc1)-c1cc(-c2ccc(Cl)cc2)c(C#N)c(=O)[nH]1 InChI=1S/C19H14ClN3O3S/c1-27(25,26)23-15-8-4-13(5-9-15)18-10-16(17(11-21)19(24)22-18)12-2-6-14(20)7-3-12/h2-10,23H,1H3,(H,22,24) IUXDCTUUNOLMQX-UHFFFAOYSA-N 222093 4-(4-Chlorophenyl)-6-(4-methanesulfonylaminophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4o) Prostaglandin G/H synthase 2 Ovis aries 3.4e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222093&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842647 335960962 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388645 CS(=O)(=O)Nc1ccc(cc1)-c1cc(-c2ccc(F)cc2)c(C#N)c(=O)[nH]1 InChI=1S/C19H14FN3O3S/c1-27(25,26)23-15-8-4-13(5-9-15)18-10-16(17(11-21)19(24)22-18)12-2-6-14(20)7-3-12/h2-10,23H,1H3,(H,22,24) SRVMANGSLZVYKG-UHFFFAOYSA-N 222094 4-(4-Fluorophenyl)-6-(4-methanesulfonylaminophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4p) Prostaglandin G/H synthase 2 Ovis aries 2.5e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222094&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842648 335960963 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388646 CS(=O)(=O)Nc1ccc(cc1)-c1cc(-c2ccco2)c(C#N)c(=O)[nH]1 InChI=1S/C17H13N3O4S/c1-25(22,23)20-12-6-4-11(5-7-12)15-9-13(16-3-2-8-24-16)14(10-18)17(21)19-15/h2-9,20H,1H3,(H,19,21) MPKXYQJNTYDUMA-UHFFFAOYSA-N 222095 4-(2-Furyl)-6-(4-methanesulfonylaminophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (4q) Prostaglandin G/H synthase 2 Ovis aries 2.9e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222095&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842649 335960964 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388647 CS(=O)(=O)Nc1ccc(cc1)-c1cc(-c2cccs2)c(C#N)c(=O)[nH]1 InChI=1S/C17H13N3O3S2/c1-25(22,23)20-12-6-4-11(5-7-12)15-9-13(16-3-2-8-24-16)14(10-18)17(21)19-15/h2-9,20H,1H3,(H,19,21) XKMCZXAWEXCZGW-UHFFFAOYSA-N 222096 6-(4-Methanesulfonylaminophenyl)-2-oxo-4-(2-thienyl)-1,2-dihydropyridine-3-carbonitrile (4r) Prostaglandin G/H synthase 2 Ovis aries 1.02e+4 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222096&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842650 335960965 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388648 CS(=O)(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccccc1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C22H22N4O4S2/c1-31(27,28)25-18-9-7-16(8-10-18)21-15-22(17-5-3-2-4-6-17)26(24-21)19-11-13-20(14-12-19)32(23,29)30/h2-14,22,25H,15H2,1H3,(H2,23,29,30) VHYUNHLRPFPUAW-UHFFFAOYSA-N 222097 1-(4-Aminosulfonylphenyl)-3-(4-methanesulfonylaminophenyl)-5-phenyl-4,5-dihydro-1H-pyrazole (6a) Prostaglandin G/H synthase 2 Ovis aries 1.3e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222097&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842651 335960966 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388649 Cc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C23H24N4O4S2/c1-16-3-5-18(6-4-16)23-15-22(17-7-9-19(10-8-17)26-32(2,28)29)25-27(23)20-11-13-21(14-12-20)33(24,30)31/h3-14,23,26H,15H2,1-2H3,(H2,24,30,31) ZHIYXGMKUUSDSE-UHFFFAOYSA-N 222098 1-(4-Aminosulfonylphenyl)-3-(4-methanesulfonylaminophenyl)-5-(4-tolyl)-4,5-dihydro-1H-pyrazole (6b) Prostaglandin G/H synthase 2 Ovis aries 7.5e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222098&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842652 335960967 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388650 CS(=O)(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C22H21ClN4O4S2/c1-32(28,29)26-18-8-4-15(5-9-18)21-14-22(16-2-6-17(23)7-3-16)27(25-21)19-10-12-20(13-11-19)33(24,30)31/h2-13,22,26H,14H2,1H3,(H2,24,30,31) XWODFOHBLAVVBU-UHFFFAOYSA-N 222099 1-(4-Aminosulfonylphenyl)-5-(4-chlorophenyl)-3-(4-methanesulfonylaminophenyl)-4,5-dihydro-1H-pyrazole (6c) Prostaglandin G/H synthase 2 Ovis aries 2.4e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222099&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842653 335960968 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388651 CS(=O)(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccc(F)cc1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C22H21FN4O4S2/c1-32(28,29)26-18-8-4-15(5-9-18)21-14-22(16-2-6-17(23)7-3-16)27(25-21)19-10-12-20(13-11-19)33(24,30)31/h2-13,22,26H,14H2,1H3,(H2,24,30,31) LICMNNDJMFGUGR-UHFFFAOYSA-N 222100 1-(4-Aminosulfonylphenyl)-5-(4-fluorophenyl)-3-(4-methanesulfonylaminophenyl)-4,5-dihydro-1H-pyrazole (6d) Prostaglandin G/H synthase 2 Ovis aries 3.9e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222100&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842654 335960969 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388652 CS(=O)(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccco1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H20N4O5S2/c1-30(25,26)23-15-6-4-14(5-7-15)18-13-19(20-3-2-12-29-20)24(22-18)16-8-10-17(11-9-16)31(21,27)28/h2-12,19,23H,13H2,1H3,(H2,21,27,28) DOZDGWIDSPKSAW-UHFFFAOYSA-N 222101 1-(4-Aminosulfonylphenyl)-5-(2-furyl)-3-(4-methanesulfonylaminophenyl)-4,5-dihydro-1H-pyrazole (6e) Prostaglandin G/H synthase 2 Ovis aries 3.5e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222101&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842655 335960970 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388653 CS(=O)(=O)Nc1ccc(cc1)C1=NN(C(C1)c1cccs1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C20H20N4O4S3/c1-30(25,26)23-15-6-4-14(5-7-15)18-13-19(20-3-2-12-29-20)24(22-18)16-8-10-17(11-9-16)31(21,27)28/h2-12,19,23H,13H2,1H3,(H2,21,27,28) BHJLVVWOTQRLCQ-UHFFFAOYSA-N 222102 1-(4-Aminosulfonylphenyl)-5-(2-thienyl)-3-(4-methanesulfonylaminophenyl)-4,5-dihydro-1H-pyrazole (6f) Prostaglandin G/H synthase 2 Ovis aries 7.8e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222102&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842656 335960971 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 388654 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 1.33e+3 Curated from the literature by BindingDB 10.1016/j.bioorg.2016.12.008 10.7270/Q208645J 28057325 aid1802579 Alsayed, SS; Elshemy, HA; Abdelgawad, MA; Abdel-Latif, MS; Abdellatif, KR Fayoum University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389171 Clc1c(sc2ccccc12)C(=O)NN1C(=O)CSC1=S InChI=1S/C12H7ClN2O2S3/c13-9-6-3-1-2-4-7(6)20-10(9)11(17)14-15-8(16)5-19-12(15)18/h1-4H,5H2,(H,14,17) NYTKUJOBYCJGTC-UHFFFAOYSA-N 222436 3-Chloro-N-(4-oxo-2-thioxothiazolidin-3-yl)benzo[b]thiophene-2-carboxamide (4) Prostaglandin G/H synthase 2 Ovis aries 2430 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222436&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842913 335961300 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389172 Clc1c(sc2ccccc12)C(=O)NN1C(=S)S\C(=C/c2cn(nc2-c2ccccc2)-c2ccccc2)C1=O InChI=1S/C28H17ClN4O2S3/c29-23-20-13-7-8-14-21(20)37-25(23)26(34)31-33-27(35)22(38-28(33)36)15-18-16-32(19-11-5-2-6-12-19)30-24(18)17-9-3-1-4-10-17/h1-16H,(H,31,34)/b22-15- IHLPCDZWFOJMCR-JCMHNJIXSA-N 222437 3-Chloro-N-{5-[(1,3-diphenyl-1H-pyrazol-4-yl)methylene]-4-oxo-2-thioxothiazolidin-3-yl}benzo[b]thiophene-2-carboxamide (5a) Prostaglandin G/H synthase 2 Ovis aries 1490 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222437&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842914 335961301 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389173 COc1ccc(cc1)-c1nn(cc1\C=C1/SC(=S)N(NC(=O)c2sc3ccccc3c2Cl)C1=O)-c1ccccc1 InChI=1S/C29H19ClN4O3S3/c1-37-20-13-11-17(12-14-20)25-18(16-33(31-25)19-7-3-2-4-8-19)15-23-28(36)34(29(38)40-23)32-27(35)26-24(30)21-9-5-6-10-22(21)39-26/h2-16H,1H3,(H,32,35)/b23-15- GGFJRPVPZBJWBV-HAHDFKILSA-N 222438 3-Chloro-N-(5-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-4-oxo-2-thioxothiazolidin-3-yl)benzo[b]thiophene-2-carboxamide (5b) Prostaglandin G/H synthase 2 Ovis aries 2610 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222438&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842915 335961302 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389174 Clc1c(sc2ccccc12)C(=O)NN1C(=S)S\C(=C/c2cn(nc2-c2ccc(Br)cc2)-c2ccccc2)C1=O InChI=1S/C28H16BrClN4O2S3/c29-18-12-10-16(11-13-18)24-17(15-33(31-24)19-6-2-1-3-7-19)14-22-27(36)34(28(37)39-22)32-26(35)25-23(30)20-8-4-5-9-21(20)38-25/h1-15H,(H,32,35)/b22-14- VWSJDFLVTAUARA-HMAPJEAMSA-N 222439 N-(5-{[3-(4-Bromophenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-4-oxo-2-thioxothiazolidin-3-yl)-3-chlorobenzo[b]thiophene-2-carboxamide (5c) Prostaglandin G/H synthase 2 Ovis aries 4880 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222439&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842916 335961303 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389175 Clc1c(sc2ccccc12)C(=O)NN1C(=S)S\C(=C/c2ccccc2)C1=O InChI=1S/C19H11ClN2O2S3/c20-15-12-8-4-5-9-13(12)26-16(15)17(23)21-22-18(24)14(27-19(22)25)10-11-6-2-1-3-7-11/h1-10H,(H,21,23)/b14-10- SZVKFEOOHWBIEP-UVTDQMKNSA-N 222440 N-(5-Benzylidene-4-oxo-2-thioxothiazolidin-3-yl)-3-chlorobenzo[b]thiophene-2-carboxamide (5d) Prostaglandin G/H synthase 2 Ovis aries 3120 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222440&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842917 335961304 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389176 COc1ccc(\C=C2/SC(=S)N(NC(=O)c3sc4ccccc4c3Cl)C2=O)cc1 InChI=1S/C20H13ClN2O3S3/c1-26-12-8-6-11(7-9-12)10-15-19(25)23(20(27)29-15)22-18(24)17-16(21)13-4-2-3-5-14(13)28-17/h2-10H,1H3,(H,22,24)/b15-10- JLJHWIXMXGFJRW-GDNBJRDFSA-N 222441 3-Chloro-N-[5-(4-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]benzo[b]thiophene-2-carboxamide (5e) Prostaglandin G/H synthase 2 Ovis aries 1890 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222441&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842918 335961305 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389177 Clc1c(sc2ccccc12)C(=O)NN1C(=S)S\C(=C/c2ccc(Cl)cc2)C1=O InChI=1S/C19H10Cl2N2O2S3/c20-11-7-5-10(6-8-11)9-14-18(25)23(19(26)28-14)22-17(24)16-15(21)12-3-1-2-4-13(12)27-16/h1-9H,(H,22,24)/b14-9- FMOBCACWVFDQNN-ZROIWOOFSA-N 222442 3-Chloro-N-[5-(4-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]benzo[b]thiophene-2-carboxamide (5f) Prostaglandin G/H synthase 2 Ovis aries 1230 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222442&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842919 335961306 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389178 COc1cc(\C=C2/SC(=S)N(NC(=O)c3sc4ccccc4c3Cl)C2=O)ccc1O InChI=1S/C20H13ClN2O4S3/c1-27-13-8-10(6-7-12(13)24)9-15-19(26)23(20(28)30-15)22-18(25)17-16(21)11-4-2-3-5-14(11)29-17/h2-9,24H,1H3,(H,22,25)/b15-9- DQIKJORLRWFRLD-DHDCSXOGSA-N 222443 3-Chloro-N-[5-(4-hydroxy-3-methoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]benzo [b]thiophene-2-carboxamide (5g) Prostaglandin G/H synthase 2 Ovis aries 4220 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222443&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842920 335961307 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389179 COc1ccc(\C=C2/SC(=S)N(NC(=O)c3sc4ccccc4c3Cl)C2=O)cc1OC InChI=1S/C21H15ClN2O4S3/c1-27-13-8-7-11(9-14(13)28-2)10-16-20(26)24(21(29)31-16)23-19(25)18-17(22)12-5-3-4-6-15(12)30-18/h3-10H,1-2H3,(H,23,25)/b16-10- IEHAYMPXZOGZKG-YBEGLDIGSA-N 222444 3-Chloro-N-[5-(3,4-dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]benzo [b]thiophene-2-carboxamide (5h) Prostaglandin G/H synthase 2 Ovis aries 670 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222444&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842921 335961308 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389180 Clc1c(sc2ccccc12)C(=O)NN1C(=S)S\C(C1=O)=C1\C(=O)Nc2ccccc12 InChI=1S/C20H10ClN3O3S3/c21-14-10-6-2-4-8-12(10)29-16(14)18(26)23-24-19(27)15(30-20(24)28)13-9-5-1-3-7-11(9)22-17(13)25/h1-8H,(H,22,25)(H,23,26)/b15-13+ XOGQTDIYEZUYBC-FYWRMAATSA-N 222445 3-Chloro-N-[4-oxo-5-(2-oxoindolin-3-ylidene)-2-thioxothiazolidin-3-yl]benzo[b]thiophene-2-carboxamide (5i) Prostaglandin G/H synthase 2 Ovis aries 1560 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222445&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842922 335961309 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389181 O=C(NN1C(=O)CSC1=S)c1cc2ccccc2o1 InChI=1S/C12H8N2O3S2/c15-10-6-19-12(18)14(10)13-11(16)9-5-7-3-1-2-4-8(7)17-9/h1-5H,6H2,(H,13,16) LUFQSEOBTYMYTA-UHFFFAOYSA-N 222446 N-(4-Oxo-2-thioxothiazolidin-3-yl)benzofuran-2-carboxamide (9) Prostaglandin G/H synthase 2 Ovis aries 1830 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222446&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842923 335961310 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389182 O=C(NN1C(=S)S\C(=C/c2cn(nc2-c2ccccc2)-c2ccccc2)C1=O)c1cc2ccccc2o1 InChI=1S/C28H18N4O3S2/c33-26(23-15-19-11-7-8-14-22(19)35-23)30-32-27(34)24(37-28(32)36)16-20-17-31(21-12-5-2-6-13-21)29-25(20)18-9-3-1-4-10-18/h1-17H,(H,30,33)/b24-16- SUEDPUSYZXWIGV-JLPGSUDCSA-N 222447 N-{5-[(1,3-Diphenyl-1H-pyrazol-4-yl)methylene]-4-oxo-2-thioxothiazolidin-3-yl}benzofuran2-carboxamide (10a) Prostaglandin G/H synthase 2 Ovis aries 4810 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222447&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842924 335961311 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389183 COc1ccc(cc1)-c1nn(cc1\C=C1/SC(=S)N(NC(=O)c2cc3ccccc3o2)C1=O)-c1ccccc1 InChI=1S/C29H20N4O4S2/c1-36-22-13-11-18(12-14-22)26-20(17-32(30-26)21-8-3-2-4-9-21)16-25-28(35)33(29(38)39-25)31-27(34)24-15-19-7-5-6-10-23(19)37-24/h2-17H,1H3,(H,31,34)/b25-16- PKWBAXUNFRSLFA-XYGWBWBKSA-N 222448 N-(5-{[3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-4-oxo-2-thioxothiazolidin-3-yl)benzofuran-2-carboxamide (10b) Prostaglandin G/H synthase 2 Ovis aries 2740 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222448&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842925 335961312 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389184 Brc1ccc(cc1)-c1nn(cc1\C=C1/SC(=S)N(NC(=O)c2cc3ccccc3o2)C1=O)-c1ccccc1 InChI=1S/C28H17BrN4O3S2/c29-20-12-10-17(11-13-20)25-19(16-32(30-25)21-7-2-1-3-8-21)15-24-27(35)33(28(37)38-24)31-26(34)23-14-18-6-4-5-9-22(18)36-23/h1-16H,(H,31,34)/b24-15- WOUKRSZATLBEJK-IWIPYMOSSA-N 222449 N-(5-{[3-(4-Bromophenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-4-oxo-2-thioxothiazolidin-3-yl)benzofuran-2-carboxamide (10c) Prostaglandin G/H synthase 2 Ovis aries 5320 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=222449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=222449&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126842926 335961313 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 389185 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 1140 Curated from the literature by BindingDB 10.1016/j.bioorg.2017.03.012 10.7270/Q2W9581F 28390993 aid1802609 El-Miligy, MM; Hazzaa, AA; El-Messmary, H; Nassra, RA; El-Hawash, SA Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397368 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 50 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397369 O=C1OC(=N\C1=C/c1ccccc1)c1cccnc1 InChI=1S/C15H10N2O2/c18-15-13(9-11-5-2-1-3-6-11)17-14(19-15)12-7-4-8-16-10-12/h1-10H/b13-9- XGRBJYKRKLNGPY-LCYFTJDESA-N 227568 4-Benzylidene-2-(pyridin-3-yl) oxazol-5(4H)-one (IIIa) Prostaglandin G/H synthase 2 Ovis aries 77 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227568&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122711717 336294635 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397370 Clc1ccc(\C=C2\N=C(OC2=O)c2cccnc2)cc1 InChI=1S/C15H9ClN2O2/c16-12-5-3-10(4-6-12)8-13-15(19)20-14(18-13)11-2-1-7-17-9-11/h1-9H/b13-8+ DHFCHMUWKNXESA-MDWZMJQESA-N 227569 4-(4-Chlorobenzylidene)-2-(pyridin-3-yl)oxazol-5(4H)-one (IIIb) Prostaglandin G/H synthase 2 Ovis aries 106 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227569&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 108936379 336294636 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397371 Oc1ccc(\C=C2\N=C(OC2=O)c2cccnc2)cc1 InChI=1S/C15H10N2O3/c18-12-5-3-10(4-6-12)8-13-15(19)20-14(17-13)11-2-1-7-16-9-11/h1-9,18H/b13-8+ UWTVRSKVEGEACS-MDWZMJQESA-N 227570 4-(4-Hydroxybenzylidene)-2-(pyridin-3-yl)oxazol-5(4H)-one (IIIc) Prostaglandin G/H synthase 2 Ovis aries 24 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227570&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 35594410 336294637 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397372 COc1ccc(\C=C2\N=C(OC2=O)c2cccnc2)cc1 InChI=1S/C16H12N2O3/c1-20-13-6-4-11(5-7-13)9-14-16(19)21-15(18-14)12-3-2-8-17-10-12/h2-10H,1H3/b14-9+ RBURMGNXRDRNQR-NTEUORMPSA-N 227571 4-(4-Methoxybenzylidene)-2-(pyridin-3-yl)oxazol-5(4H)-one (IIId) Prostaglandin G/H synthase 2 Ovis aries 59 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227571&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6112945 336294638 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397373 CN(C)c1ccc(\C=C2\N=C(OC2=O)c2cccnc2)cc1 InChI=1S/C17H15N3O2/c1-20(2)14-7-5-12(6-8-14)10-15-17(21)22-16(19-15)13-4-3-9-18-11-13/h3-11H,1-2H3/b15-10+ XTEDAFQADZLEDX-XNTDXEJSSA-N 227572 4-(4-(Dimethylamino)benzylidene)-2-(pyridin-3-yl)oxazol-5(4H)-one (IIIe) Prostaglandin G/H synthase 2 Ovis aries 19 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227572&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 35594376 336294639 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397374 Oc1ccccc1\C=C1/N=C(OC1=O)c1cccnc1 InChI=1S/C15H10N2O3/c18-13-6-2-1-4-10(13)8-12-15(19)20-14(17-12)11-5-3-7-16-9-11/h1-9,18H/b12-8- ZWRMPTAEEFZYQT-WQLSENKSSA-N 227573 4-(2-Hydroxybenzylidene)-2-(pyridin-3-yl)oxazol-5(4H)-one (IIIf) Prostaglandin G/H synthase 2 Ovis aries 85 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227573&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122711699 336294640 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397375 O=C1OC(=N\C1=C/c1cccnc1)c1cccnc1 InChI=1S/C14H9N3O2/c18-14-12(7-10-3-1-5-15-8-10)17-13(19-14)11-4-2-6-16-9-11/h1-9H/b12-7- RHTZKOFYATXLND-GHXNOFRVSA-N 227574 2-(pyridin-3-yl)-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one (IIIg) Prostaglandin G/H synthase 2 Ovis aries 75 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227574&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963295 336294641 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397376 O=C1NN(C(=N\C1=C\c1ccccc1)c1cccnc1)c1ccccc1 InChI=1S/C21H16N4O/c26-21-19(14-16-8-3-1-4-9-16)23-20(17-10-7-13-22-15-17)25(24-21)18-11-5-2-6-12-18/h1-15H,(H,24,26)/b19-14+ LLGBYQLMKFFCDP-XMHGGMMESA-N 227575 5-Benzylidene-2-phenyl-3-(pyridin-3-yl)-1,2-dihydro-1,2,4-triazin-6(5H)-one (IVa) Prostaglandin G/H synthase 2 Ovis aries 35 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227575&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963296 336294642 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397377 Clc1ccc(\C=C2\N=C(N(NC2=O)c2ccccc2)c2cccnc2)cc1 InChI=1S/C21H15ClN4O/c22-17-10-8-15(9-11-17)13-19-21(27)25-26(18-6-2-1-3-7-18)20(24-19)16-5-4-12-23-14-16/h1-14H,(H,25,27)/b19-13+ IUWJHUYCISYQCS-CPNJWEJPSA-N 227576 5-(4-Chlorobenzylidene)-2-phenyl-3-(pyridin-3-yl)-1,2-dihydro-1,2,4-triazin-6(5H)-one (IVb) Prostaglandin G/H synthase 2 Ovis aries 34 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227576&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963297 336294643 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397378 Oc1ccc(\C=C2\N=C(N(NC2=O)c2ccccc2)c2cccnc2)cc1 InChI=1S/C21H16N4O2/c26-18-10-8-15(9-11-18)13-19-21(27)24-25(17-6-2-1-3-7-17)20(23-19)16-5-4-12-22-14-16/h1-14,26H,(H,24,27)/b19-13+ SSWHBHQMBBUPRN-CPNJWEJPSA-N 227577 5-(4-Hydroxybenzylidene)-2-phenyl-3-(pyridin-3-yl)-1,2-dihydro-1,2,4-triazin-6(5H)-one (IVc) Prostaglandin G/H synthase 2 Ovis aries 19 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227577&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963298 336294644 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397379 COc1ccc(\C=C2\N=C(N(NC2=O)c2ccccc2)c2cccnc2)cc1 InChI=1S/C22H18N4O2/c1-28-19-11-9-16(10-12-19)14-20-22(27)25-26(18-7-3-2-4-8-18)21(24-20)17-6-5-13-23-15-17/h2-15H,1H3,(H,25,27)/b20-14+ BNAKUNINWOCARC-XSFVSMFZSA-N 227578 5-(4-Methoxybenzylidene)-2-phenyl-3-(pyridin-3-yl)-1,2-dihydro-1,2,4-triazin-6(5H)-one (IVd) Prostaglandin G/H synthase 2 Ovis aries 11 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227578&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963299 336294645 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397380 CN(C)c1ccc(\C=C2\N=C(N(NC2=O)c2ccccc2)c2cccnc2)cc1 InChI=1S/C23H21N5O/c1-27(2)19-12-10-17(11-13-19)15-21-23(29)26-28(20-8-4-3-5-9-20)22(25-21)18-7-6-14-24-16-18/h3-16H,1-2H3,(H,26,29)/b21-15+ ZCBORCZXIYDHAE-RCCKNPSSSA-N 227579 5-(4-(Dimethylamino) benzylidene)-2-phenyl-3-(pyridin-3-yl)-1,2-dihydro-1,2,4-triazin-6(5H)-one (IVe) Prostaglandin G/H synthase 2 Ovis aries 19 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227579&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963300 336294646 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397381 Oc1ccccc1\C=C1\N=C(N(NC1=O)c1ccccc1)c1cccnc1 InChI=1S/C21H16N4O2/c26-19-11-5-4-7-15(19)13-18-21(27)24-25(17-9-2-1-3-10-17)20(23-18)16-8-6-12-22-14-16/h1-14,26H,(H,24,27)/b18-13+ CPRAYMNGTODIMN-QGOAFFKASA-N 227580 5-(2-Hydroxybenzylidene)-2-phenyl-3-(pyridin-3-yl)-1,2-dihydro-1,2,4-triazin-6(5H)-one (IVf) Prostaglandin G/H synthase 2 Ovis aries 17 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227580&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963301 336294647 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 397382 O=C1NN(C(=N\C1=C\c1cccnc1)c1cccnc1)c1ccccc1 InChI=1S/C20H15N5O/c26-20-18(12-15-6-4-10-21-13-15)23-19(16-7-5-11-22-14-16)25(24-20)17-8-2-1-3-9-17/h1-14H,(H,24,26)/b18-12+ IJIBGBCHDYJAES-LDADJPATSA-N 227581 2-Phenyl-3-(pyridin-3-yl)-5-(pyridin-3-ylmethylene)-1,2-dihydro-1,2,4-triazin-6(5H)-one (IVg) Prostaglandin G/H synthase 2 Ovis aries 14 8 25.00 C Curated from the literature by BindingDB 10.1016/j.bioorg.2017.04.012 10.7270/Q2WQ02PQ 28500957 aid1802788 Mohamed, LW; El-Badry, OM; El-Ansary, AK; Ismael, A Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=227581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=227581&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 126963302 336294648 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 406529 CC(C)Cc1ccc(cc1)C1=C\C(=C/c2ccccc2Cl)C(=O)O1 InChI=1S/C21H19ClO2/c1-14(2)11-15-7-9-16(10-8-15)20-13-18(21(23)24-20)12-17-5-3-4-6-19(17)22/h3-10,12-14H,11H2,1-2H3/b18-12+ TVBJDDOGYNSNLZ-LDADJPATSA-N 233050 3-(2-Chlorobenzylidene)-5-(4-isobutylphenyl)-2(3H)-furanone (3) Prostaglandin G/H synthase 2 Ovis aries 2.4e+3 Curated from the literature by BindingDB 10.3109/14756360903179435 10.7270/Q26H4G8J 19883244 aid1802934 Alam, MM; Husain, A; Hasan, SM; Khanna, S; Shaquiquzzaman, M Jamia Hamdard http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233050&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 129010584 340093144 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 406530 CC(C)Cc1ccc(cc1)C1=C\C(=C/c2ccc(F)cc2)C(=O)O1 InChI=1S/C21H19FO2/c1-14(2)11-15-3-7-17(8-4-15)20-13-18(21(23)24-20)12-16-5-9-19(22)10-6-16/h3-10,12-14H,11H2,1-2H3/b18-12+ OTQWRISCOPEKGA-LDADJPATSA-N 233051 3-(4-Fluorobenzylidene)-5-(4-isobutylphenyl)-2(3H)-furanone (9) Prostaglandin G/H synthase 2 Ovis aries 3.8e+3 Curated from the literature by BindingDB 10.3109/14756360903179435 10.7270/Q26H4G8J 19883244 aid1802934 Alam, MM; Husain, A; Hasan, SM; Khanna, S; Shaquiquzzaman, M Jamia Hamdard http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233051&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 129010585 340093145 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 406531 CC(C)Cc1ccc(cc1)C1=C\C(=C/c2c(Cl)cccc2Cl)C(=O)O1 InChI=1S/C21H18Cl2O2/c1-13(2)10-14-6-8-15(9-7-14)20-12-16(21(24)25-20)11-17-18(22)4-3-5-19(17)23/h3-9,11-13H,10H2,1-2H3/b16-11+ OPCYGCQJDWJEIA-LFIBNONCSA-N 233052 3-(2,6-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2(3H)-furanone (13) Prostaglandin G/H synthase 2 Ovis aries 1.8e+3 Curated from the literature by BindingDB 10.3109/14756360903179435 10.7270/Q26H4G8J 19883244 aid1802934 Alam, MM; Husain, A; Hasan, SM; Khanna, S; Shaquiquzzaman, M Jamia Hamdard http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233052&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 129010586 340093146 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 406532 CC(C)Cc1ccc(cc1)C1=C\C(=C/c2ccc(Cl)cc2Cl)C(=O)O1 InChI=1S/C21H18Cl2O2/c1-13(2)9-14-3-5-15(6-4-14)20-11-17(21(24)25-20)10-16-7-8-18(22)12-19(16)23/h3-8,10-13H,9H2,1-2H3/b17-10+ ZKLAGEHVLPQVLD-LICLKQGHSA-N 233053 3-(2,4-Dichlorobenzylidene)-5-(4-isobutylphenyl)-2(3H)-furanone (14) Prostaglandin G/H synthase 2 Ovis aries 2.2e+3 Curated from the literature by BindingDB 10.3109/14756360903179435 10.7270/Q26H4G8J 19883244 aid1802934 Alam, MM; Husain, A; Hasan, SM; Khanna, S; Shaquiquzzaman, M Jamia Hamdard http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=233053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=233053&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 129010587 340093147 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410454 O=c1oc2ccccc2cc1-c1nnc(o1)-c1ccccc1 InChI=1S/C17H10N2O3/c20-17-13(10-12-8-4-5-9-14(12)21-17)16-19-18-15(22-16)11-6-2-1-3-7-11/h1-10H XCWSXFUBKNIMTJ-UHFFFAOYSA-N 235660 3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (4a) Prostaglandin G/H synthase 2 Ovis aries 8.7e+3 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235660&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 826603 375077310 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410455 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 30500 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410456 Clc1ccc(cc1)-c1nnc(o1)-c1cc2ccccc2oc1=O InChI=1S/C17H9ClN2O3/c18-12-7-5-10(6-8-12)15-19-20-16(23-15)13-9-11-3-1-2-4-14(11)22-17(13)21/h1-9H BKSIRJBXYHOZTL-UHFFFAOYSA-N 235661 3-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chromen-2-one (4b) Prostaglandin G/H synthase 2 Ovis aries 1.2e+3 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235661&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 767278 375077311 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410457 Cc1ccc(cc1)-c1nnc(o1)-c1cc2ccccc2oc1=O InChI=1S/C18H12N2O3/c1-11-6-8-12(9-7-11)16-19-20-17(23-16)14-10-13-4-2-3-5-15(13)22-18(14)21/h2-10H,1H3 BYOVHLGRJGKKNQ-UHFFFAOYSA-N 235662 3-(5-p-Tolyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (4c) Prostaglandin G/H synthase 2 Ovis aries 1.18e+3 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235662&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2054741 375077304 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410458 Clc1ccc(-c2nnc(o2)-c2cc3ccccc3oc2=O)c(Cl)c1 InChI=1S/C17H8Cl2N2O3/c18-10-5-6-11(13(19)8-10)15-20-21-16(24-15)12-7-9-3-1-2-4-14(9)23-17(12)22/h1-8H SHBVTOCYOSZOQS-UHFFFAOYSA-N 235663 3-[5-(2,4-Dichloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chromen-2-one (4e) Prostaglandin G/H synthase 2 Ovis aries 4e+2 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235663&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5122491 375077313 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410459 Clc1ccc(Nc2nnc(o2)-c2cc3ccccc3oc2=O)cc1 InChI=1S/C17H10ClN3O3/c18-11-5-7-12(8-6-11)19-17-21-20-15(24-17)13-9-10-3-1-2-4-14(10)23-16(13)22/h1-9H,(H,19,21) FYRGUPVXPASVDB-UHFFFAOYSA-N 235664 3-[5-(4-Chloro-phenylamino)-[1,3,4]oxadiazol-2-yl]-chromen-2-one (6b) Prostaglandin G/H synthase 2 Ovis aries >1.00e+5 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235664&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 134686712 375077305 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410460 Cc1ccccc1Nc1nnc(o1)-c1cc2ccccc2oc1=O InChI=1S/C18H13N3O3/c1-11-6-2-4-8-14(11)19-18-21-20-16(24-18)13-10-12-7-3-5-9-15(12)23-17(13)22/h2-10H,1H3,(H,19,21) YRTPDHKRIOWNNC-UHFFFAOYSA-N 235665 3-(5-o-Tolylamino-[1,3,4]oxadiazol-2-yl)-chromen-2-one (6e) Prostaglandin G/H synthase 2 Ovis aries 3.66e+4 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235665&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 134686716 375077314 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410461 Clc1ccc(cc1)C(=O)Nc1nnc(o1)-c1cc2ccccc2oc1=O InChI=1S/C18H10ClN3O4/c19-12-7-5-10(6-8-12)15(23)20-18-22-21-16(26-18)13-9-11-3-1-2-4-14(11)25-17(13)24/h1-9H,(H,20,22,23) DFKQGXFUTINVCQ-UHFFFAOYSA-N 235666 4-Chloro-N-[5-(2-oxo-2H-chromen-3-yl)-[1,3,4]oxadiazol-2-yl]-benzamide (8b) Prostaglandin G/H synthase 2 Ovis aries >1.00e+5 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235666&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 134686713 375077306 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 410462 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 9e+1 8 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.550890 10.7270/Q21J98NP 21314246 aid1803031 Akhter, M; Akhter, N; Alam, MM; Zaman, MS; Saha, R; Kumar, A Jamia Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015965 C[C@@]1(CC=C2C(CCC3[C@](C)(CO)CCC[C@@]23C)C1)C=C InChI=1S/C20H32O/c1-5-18(2)12-9-16-15(13-18)7-8-17-19(3,14-21)10-6-11-20(16,17)4/h5,9,15,17,21H,1,6-8,10-14H2,2-4H3/t15?,17?,18-,19-,20-/m0/s1 YSFNIVKHYKBKHI-SAETXWKOSA-N 50097212 ((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-methanol::CHEMBL115590::acanthol Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097212&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9882419 103994544 CHEMBL115590 ZINC27099820 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015966 C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1)C=C InChI=1S/C20H30O2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h5,9,14,16H,1,6-8,10-13H2,2-4H3,(H,21,22)/t14?,16?,18-,19-,20+/m0/s1 TVHDZSRRHQKNEZ-BDAJPOSXSA-N 50097211 (1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid::CHEMBL152325::acanthoic acid Prostaglandin G/H synthase 2 Ovis aries 790400 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097211&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9861219 103994543 CHEMBL152325 ZINC27639726 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015968 COC(=O)[C@]1(C)CCC[C@]2(C)C1CCC1C[C@](C)(CC=C21)C=C InChI=1S/C21H32O2/c1-6-19(2)13-10-16-15(14-19)8-9-17-20(16,3)11-7-12-21(17,4)18(22)23-5/h6,10,15,17H,1,7-9,11-14H2,2-5H3/t15?,17?,19-,20-,21+/m0/s1 ZDKRUBUMOILNFK-UMYBPNPHSA-N 50097196 (1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid methyl ester::CHEMBL356018 Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097196&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44368677 103994528 CHEMBL356018 ZINC27643384 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015971 C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(=O)NN)C1)C=C InChI=1S/C20H32N2O/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(23)22-21/h5,9,14,16H,1,6-8,10-13,21H2,2-4H3,(H,22,23)/t14?,16?,18-,19-,20+/m0/s1 AURNZDRKZMLHPN-BDAJPOSXSA-N 50097201 (1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid hydrazide::CHEMBL116328 Prostaglandin G/H synthase 2 Ovis aries 41900 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097201&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9948850 103994533 CHEMBL116328 ZINC27093364 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015975 C[C@@]1(CC=C2C(CCC3[C@](C)(CCCC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C23H36O2/c1-5-21(2)15-11-18-17(16-21)9-10-19-22(3,12-6-8-20(24)25)13-7-14-23(18,19)4/h5,11,17,19H,1,6-10,12-16H2,2-4H3,(H,24,25)/t17?,19?,21-,22+,23-/m0/s1 SULJGIKDKXUDLN-LDNYZGLHSA-N 50097207 4-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-butyric acid::CHEMBL117635 Prostaglandin G/H synthase 2 Ovis aries 49400 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097207&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9798239 103994539 CHEMBL117635 ZINC27101320 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015978 C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(=O)NO)C1)C=C InChI=1S/C20H31NO2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(22)21-23/h5,9,14,16,23H,1,6-8,10-13H2,2-4H3,(H,21,22)/t14?,16?,18-,19-,20+/m0/s1 HEFVETXYFDNJSY-BDAJPOSXSA-N 50097194 (1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid hydroxyamide::CHEMBL345533 Prostaglandin G/H synthase 2 Ovis aries 818900 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097194&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9948878 103994526 CHEMBL345533 ZINC27641803 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015980 COCC[C@@]1(C)CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1 InChI=1S/C21H34O3/c1-19(12-13-24-4)11-8-16-15(14-19)6-7-17-20(16,2)9-5-10-21(17,3)18(22)23/h8,15,17H,5-7,9-14H2,1-4H3,(H,22,23)/t15?,17?,19-,20+,21-/m1/s1 RKRKYGRCYRXULL-MHPBUQJSSA-N 50097203 (1R,4aR,7S)-7-(2-Methoxy-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid::CHEMBL153497 Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097203&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9840662 103994535 CHEMBL153497 ZINC27640911 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015981 C[C@@]1(CC=C2C(CCC3[C@](C)(CCC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C22H34O2/c1-5-20(2)13-9-17-16(15-20)7-8-18-21(3,14-10-19(23)24)11-6-12-22(17,18)4/h5,9,16,18H,1,6-8,10-15H2,2-4H3,(H,23,24)/t16?,18?,20-,21-,22-/m0/s1 YVCINYUJSBPRQS-YSDQLLENSA-N 50097210 3-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-propionic acid::CHEMBL324837 Prostaglandin G/H synthase 2 Ovis aries 105000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097210&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9840502 103994542 CHEMBL324837 ZINC27099287 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015984 CC[C@@]1(C)CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1 InChI=1S/C20H32O2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h9,14,16H,5-8,10-13H2,1-4H3,(H,21,22)/t14?,16?,18-,19-,20+/m0/s1 IFKGALZTVMPCIH-BDAJPOSXSA-N 50097205 (1R,4aR,7S)-7-Ethyl-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid::CHEMBL435432 Prostaglandin G/H synthase 2 Ovis aries 425000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097205&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44368313 103994537 CHEMBL435432 ZINC27640934 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015986 C[C@]1(CC(F)F)CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1 InChI=1S/C20H30F2O2/c1-18(12-16(21)22)10-7-14-13(11-18)5-6-15-19(14,2)8-4-9-20(15,3)17(23)24/h7,13,15-16H,4-6,8-12H2,1-3H3,(H,23,24)/t13?,15?,18-,19-,20+/m0/s1 UOSXMUVQMSJAOK-HDLYMOLYSA-N 50097209 (1R,4aR,7S)-7-(2,2-Difluoro-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid::CHEMBL153495 Prostaglandin G/H synthase 2 Ovis aries 796000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097209&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44368376 103994541 CHEMBL153495 ZINC27640423 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015988 C[C@]1(CCF)CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1 InChI=1S/C20H31FO2/c1-18(11-12-21)10-7-15-14(13-18)5-6-16-19(15,2)8-4-9-20(16,3)17(22)23/h7,14,16H,4-6,8-13H2,1-3H3,(H,22,23)/t14?,16?,18-,19+,20-/m1/s1 QILUCABROJMZBR-IAJRKJRPSA-N 50097200 (1R,4aR,7S)-7-(2-Fluoro-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid::CHEMBL151859 Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097200&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44368385 103994532 CHEMBL151859 ZINC27641753 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015991 C[C@@]1(CC=C2C(CCC3[C@](C)(CC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C21H32O2/c1-5-19(2)12-9-16-15(13-19)7-8-17-20(3,14-18(22)23)10-6-11-21(16,17)4/h5,9,15,17H,1,6-8,10-14H2,2-4H3,(H,22,23)/t15?,17?,19-,20-,21-/m0/s1 JPTYTZASFHUDCV-HQIBCSSTSA-N 50097199 ((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-acetic acid::CHEMBL117763 Prostaglandin G/H synthase 2 Ovis aries 82300 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097199&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9797003 103994531 CHEMBL117763 ZINC27096181 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015992 C[C@@]1(C[C@@H]2O[C@]22C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1)C1CO1 InChI=1S/C20H30O4/c1-17(15-11-23-15)9-12-5-6-13-18(2,16(21)22)7-4-8-19(13,3)20(12)14(10-17)24-20/h12-15H,4-11H2,1-3H3,(H,21,22)/t12?,13?,14-,15?,17+,18+,19+,20+/m0/s1 BAVAPCQGJJCZCO-RNDGJMBKSA-N 50097206 2,6,12-trimethyl-12-(2-oxiranyl)-15-oxatetracyclo[8.5.0.01,14.02,7]pentadecane-6-carboxylic acid::CHEMBL357063 Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097206&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44368294 103994538 CHEMBL357063 ZINC40741553 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015993 C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(N)=O)C1)C=C InChI=1S/C20H31NO/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h5,9,14,16H,1,6-8,10-13H2,2-4H3,(H2,21,22)/t14?,16?,18-,19-,20+/m0/s1 FSECCYUGWXZVHQ-BDAJPOSXSA-N 50097208 (1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid amide::CHEMBL345290 Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097208&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9839351 103994540 CHEMBL345290 ZINC27639897 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015995 CC(=O)OCC[C@@]1(C)CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1 InChI=1S/C22H34O4/c1-15(23)26-13-12-20(2)11-8-17-16(14-20)6-7-18-21(17,3)9-5-10-22(18,4)19(24)25/h8,16,18H,5-7,9-14H2,1-4H3,(H,24,25)/t16?,18?,20-,21+,22-/m1/s1 IIPCIWPAEHRPHF-AMXXQORMSA-N 50097202 (1R,4aR,7S)-7-(2-Acetoxy-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid::CHEMBL357965 Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097202&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9820390 103994534 CHEMBL357965 ZINC27640206 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015960 C[C@@]1(CC=C2C(CCC3[C@](C)(CCC\C=C\C(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C25H38O2/c1-5-23(2)17-13-20-19(18-23)11-12-21-24(3,15-9-16-25(20,21)4)14-8-6-7-10-22(26)27/h5,7,10,13,19,21H,1,6,8-9,11-12,14-18H2,2-4H3,(H,26,27)/b10-7+/t19?,21?,23-,24+,25-/m0/s1 RRWSYMHVTCDSNN-FOGCZXIISA-N 50097197 (E)-6-((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-hex-2-enoic acid::CHEMBL324730 Prostaglandin G/H synthase 2 Ovis aries 13200 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097197&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10361821 103994529 CHEMBL324730 ZINC27097997 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015961 C[C@]1(CCO)CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(O)=O)C1 InChI=1S/C20H32O3/c1-18(11-12-21)10-7-15-14(13-18)5-6-16-19(15,2)8-4-9-20(16,3)17(22)23/h7,14,16,21H,4-6,8-13H2,1-3H3,(H,22,23)/t14?,16?,18-,19+,20-/m1/s1 KGLSHOVCCVTFOY-IAJRKJRPSA-N 50097198 (1R,4aR,7S)-7-(2-Hydroxy-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid::CHEMBL359354 Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097198&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44368274 103994530 CHEMBL359354 ZINC27640247 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015962 C[C@]1(CCF)CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(F)=O)C1 InChI=1S/C20H30F2O/c1-18(11-12-21)10-7-15-14(13-18)5-6-16-19(15,2)8-4-9-20(16,3)17(22)23/h7,14,16H,4-6,8-13H2,1-3H3/t14?,16?,18-,19+,20-/m1/s1 KEHIUHIQIPZQRY-IAJRKJRPSA-N 50097195 (1R,4aR,7S)-7-(2-Fluoro-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carbonyl fluoride::CHEMBL357801 Prostaglandin G/H synthase 2 Ovis aries 193700 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097195&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44368275 103994527 CHEMBL357801 ZINC27640270 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50015964 C[C@@]1(CC=C2C(CCC3[C@](C)(CCCCC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C24H38O2/c1-5-22(2)16-12-19-18(17-22)10-11-20-23(3,13-7-6-9-21(25)26)14-8-15-24(19,20)4/h5,12,18,20H,1,6-11,13-17H2,2-4H3,(H,25,26)/t18?,20?,22-,23+,24-/m0/s1 IFIXXFKTBDCXOX-OBWQMAAISA-N 50097204 5-((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-pentanoic acid::CHEMBL116532 Prostaglandin G/H synthase 2 Ovis aries 38700 ChEMBL 10.1016/s0960-894x(01)00004-x 10.7270/Q2FJ2G15 11229771 Suh, YG; Kim, YH; Park, MH; Choi, YH; Lee, HK; Moon, JY; Min, KH; Shin, DY; Jung, JK; Park, OH; Jeon, RO; Park, HS; Kang, SA Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097204&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9906813 103994536 CHEMBL116532 ZINC27093784 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019607 C[C@]1(CCC(=O)NC1=O)N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O InChI=1S/C14H11N3O6/c1-14(5-4-10(18)15-13(14)21)16-11(19)8-3-2-7(17(22)23)6-9(8)12(16)20/h2-3,6H,4-5H2,1H3,(H,15,18,21)/t14-/m1/s1 JYJXLTUJYMFOCC-CQSZACIVSA-N 50111211 2-((R)-3-Methyl-2,6-dioxo-piperidin-3-yl)-5-nitro-isoindole-1,3-dione::CHEMBL8781 Prostaglandin G/H synthase 2 Ovis aries 1510 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111211&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10591552 104005834 CHEMBL8781 ZINC13440207 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019611 O=C1N(C(=O)c2ccccc12)c1c[nH]c(=O)[nH]c1=O InChI=1S/C12H7N3O4/c16-9-8(5-13-12(19)14-9)15-10(17)6-3-1-2-4-7(6)11(15)18/h1-5H,(H2,13,14,16,19) DQCXJNJOELHPGW-UHFFFAOYSA-N 50111220 2-(2,4-Dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-isoindole-1,3-dione::CHEMBL266599 Prostaglandin G/H synthase 2 Ovis aries 3810 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111220&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 316338 104005843 CHEMBL266599 ZINC01764952 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019612 O=C1N(N2CCC(=O)NC2=O)C(=O)c2ccccc12 InChI=1S/C12H9N3O4/c16-9-5-6-14(12(19)13-9)15-10(17)7-3-1-2-4-8(7)11(15)18/h1-4H,5-6H2,(H,13,16,19) OLUNQQVFUJWJHU-UHFFFAOYSA-N 50111207 2-(2,4-Dioxo-tetrahydro-pyrimidin-1-yl)-isoindole-1,3-dione::CHEMBL9123 Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111207&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44265839 104005830 CHEMBL9123 ZINC13440211 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019613 O=C1N(C2CCCNC2=O)C(=O)c2ccccc12 InChI=1S/C13H12N2O3/c16-11-10(6-3-7-14-11)15-12(17)8-4-1-2-5-9(8)13(15)18/h1-2,4-5,10H,3,6-7H2,(H,14,16) ZLYHJKFZUWNUEQ-UHFFFAOYSA-N 50111219 2-(2-Oxo-piperidin-3-yl)-isoindole-1,3-dione::CHEMBL268643 Prostaglandin G/H synthase 2 Ovis aries 1210 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111219&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 135339 104005842 CHEMBL268643 ZINC01410329 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019614 Cc1cc(C)c(C)c(c1)N1C(=O)c2ccccc2C1=O InChI=1S/C17H15NO2/c1-10-8-11(2)12(3)15(9-10)18-16(19)13-6-4-5-7-14(13)17(18)20/h4-9H,1-3H3 FJKRILLXRFSKAR-UHFFFAOYSA-N 50111213 2-(2,3,5-Trimethyl-phenyl)-isoindole-1,3-dione::CHEMBL9254 Prostaglandin G/H synthase 2 Ovis aries 1180 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111213&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44265818 104005836 CHEMBL9254 ZINC13440213 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019620 C[C@]1(CCC(=O)NC1=O)N1C(=O)c2ccccc2C1=O InChI=1S/C14H12N2O4/c1-14(7-6-10(17)15-13(14)20)16-11(18)8-4-2-3-5-9(8)12(16)19/h2-5H,6-7H2,1H3,(H,15,17,20)/t14-/m1/s1 DFCNZYVSWVECOW-CQSZACIVSA-N 50111217 2-((R)-3-Methyl-2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione::CHEMBL8734 Prostaglandin G/H synthase 2 Ovis aries 730 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111217&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 176095 104005840 CHEMBL8734 ZINC03810792 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019622 O=C1N(CCn2ccc(=O)[nH]c2=O)C(=O)c2ccccc12 InChI=1S/C14H11N3O4/c18-11-5-6-16(14(21)15-11)7-8-17-12(19)9-3-1-2-4-10(9)13(17)20/h1-6H,7-8H2,(H,15,18,21) XHEVANCHHPZITL-UHFFFAOYSA-N 50111214 2-[2-(2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-ethyl]-isoindole-1,3-dione::CHEMBL8998 Prostaglandin G/H synthase 2 Ovis aries 650 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111214&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11822197 104005837 CHEMBL8998 ZINC12352327 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019624 COc1cc(OC)nc(n1)-n1c(O)cc2ccccc2c1=O InChI=1S/C15H13N3O4/c1-21-11-8-12(22-2)17-15(16-11)18-13(19)7-9-5-3-4-6-10(9)14(18)20/h3-8,19H,1-2H3 XNZBJPREYBLRJU-UHFFFAOYSA-N 50111212 2-(4,6-Dimethoxy-pyrimidin-2-yl)-4H-isoquinoline-1,3-dione::CHEMBL441214 Prostaglandin G/H synthase 2 Ovis aries 3570 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111212&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91931908 104005835 CHEMBL441214 ZINC13440224 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019625 COc1cc(C)nc(n1)-n1c(O)cc2ccccc2c1=O InChI=1S/C15H13N3O3/c1-9-7-12(21-2)17-15(16-9)18-13(19)8-10-5-3-4-6-11(10)14(18)20/h3-8,19H,1-2H3 PSSGKUUPHRKKJC-UHFFFAOYSA-N 50111215 2-(4-Methoxy-6-methyl-pyrimidin-2-yl)-4H-isoquinoline-1,3-dione::CHEMBL8979 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111215&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91931909 104005838 CHEMBL8979 ZINC13440222 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019626 O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12 InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17) UEJJHQNACJXSKW-UHFFFAOYSA-N 50070114 (+/-)-thalidomide::2-(2,6-Dioxo-piperidin-3-yl)-isoindole-1,3-dione::2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione::CHEMBL468::K-17::THALIDOMIDE::Thalomid::US11059801, Compound D-62::[(R,S)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070114&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search EF2 4CI1,8BC7,5AMI,5AMH,7BQU,5YIZ,7PSO,4V32,4V2Y,5OH1,5AMK,5AMJ,6R13,6R12,6R19,6R18,6R1C,6R1A,6R1W,6R0U,6R0S,5YJ0,4TZC 5426 103964042 74947 CHEMBL468 DB01041 7327 C07910 ZINC01530948 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019627 C[C@]1(CCC(=O)NC1=O)N1C(=O)c2cccc(N)c2C1=O InChI=1S/C14H13N3O4/c1-14(6-5-9(18)16-13(14)21)17-11(19)7-3-2-4-8(15)10(7)12(17)20/h2-4H,5-6,15H2,1H3,(H,16,18,21)/t14-/m1/s1 VZTDWPXKIYLLAT-CQSZACIVSA-N 50111222 4-Amino-2-((R)-3-methyl-2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione::CHEMBL9192 Prostaglandin G/H synthase 2 Ovis aries 1850 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111222&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10755697 104005845 CHEMBL9192 ZINC03940471 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019628 Cc1cc(C)nc(n1)-n1c(O)cc2ccccc2c1=O InChI=1S/C15H13N3O2/c1-9-7-10(2)17-15(16-9)18-13(19)8-11-5-3-4-6-12(11)14(18)20/h3-8,19H,1-2H3 PBJHIRLDZHZRQU-UHFFFAOYSA-N 50111224 2-(4,6-Dimethyl-pyrimidin-2-yl)-4H-isoquinoline-1,3-dione::CHEMBL268215 Prostaglandin G/H synthase 2 Ovis aries 8330 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111224&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91931910 104005847 CHEMBL268215 ZINC13440220 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019629 Cc1cc(C)nc(c1)-n1c(O)cc2ccccc2c1=O InChI=1S/C16H14N2O2/c1-10-7-11(2)17-14(8-10)18-15(19)9-12-5-3-4-6-13(12)16(18)20/h3-9,19H,1-2H3 DPFPSQCDNBOCCL-UHFFFAOYSA-N 50111208 2-(4,6-Dimethyl-pyridin-2-yl)-4H-isoquinoline-1,3-dione::CHEMBL9273 Prostaglandin G/H synthase 2 Ovis aries 6670 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111208&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91931907 104005831 CHEMBL9273 ZINC13440218 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019630 C[C@]1(CCC(=O)NC1=O)N1C(=O)c2cccc(c2C1=O)[N+]([O-])=O InChI=1S/C14H11N3O6/c1-14(6-5-9(18)15-13(14)21)16-11(19)7-3-2-4-8(17(22)23)10(7)12(16)20/h2-4H,5-6H2,1H3,(H,15,18,21)/t14-/m1/s1 SSFKURSGJRBEPO-CQSZACIVSA-N 50111221 2-((R)-3-Methyl-2,6-dioxo-piperidin-3-yl)-4-nitro-isoindole-1,3-dione::CHEMBL9191 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111221&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10829259 104005844 CHEMBL9191 ZINC13440205 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019632 Cc1cc(C)cc(c1)-n1c(O)cc2ccccc2c1=O InChI=1S/C17H15NO2/c1-11-7-12(2)9-14(8-11)18-16(19)10-13-5-3-4-6-15(13)17(18)20/h3-10,19H,1-2H3 NLCVVBLKNZQCIA-UHFFFAOYSA-N 50111210 2-(3,5-Dimethyl-phenyl)-4H-isoquinoline-1,3-dione::CHEMBL8783 Prostaglandin G/H synthase 2 Ovis aries 38500 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111210&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54117161 104005833 CHEMBL8783 ZINC12352320 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019633 Cc1cc(C)c(C)c(N2C(=O)c3ccccc3C2=O)c1C InChI=1S/C18H17NO2/c1-10-9-11(2)13(4)16(12(10)3)19-17(20)14-7-5-6-8-15(14)18(19)21/h5-9H,1-4H3 IPJVHLKFRAXJAQ-UHFFFAOYSA-N 50111209 2-(2,3,5,6-Tetramethyl-phenyl)-isoindole-1,3-dione::CHEMBL9007 Prostaglandin G/H synthase 2 Ovis aries 670 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111209&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10612708 104005832 CHEMBL9007 ZINC13440215 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50019636 Cc1cc(C)cc(c1)N1C(=O)c2ccccc2C1=O InChI=1S/C16H13NO2/c1-10-7-11(2)9-12(8-10)17-15(18)13-5-3-4-6-14(13)16(17)19/h3-9H,1-2H3 QRYFDLJSGLUOCO-UHFFFAOYSA-N 50111223 2-(3,5-Dimethyl-phenyl)-isoindole-1,3-dione::CHEMBL9255 Prostaglandin G/H synthase 2 Ovis aries 13200 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111223&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 693734 104005846 CHEMBL9255 ZINC00065912 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50018787 OC(=O)Cc1cccc(C(=O)c2ccc(Cl)cc2)c1[N+]([O-])=O InChI=1S/C15H10ClNO5/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(8-13(18)19)14(12)17(21)22/h1-7H,8H2,(H,18,19) HGIRZIGBWAKVRS-UHFFFAOYSA-N 50012909 CHEMBL76451::[3-(4-Chloro-benzoyl)-2-nitro-phenyl]-acetic acid Prostaglandin G/H synthase 2 Ovis aries >1000000 ChEMBL 10.1021/jm00170a039 10.7270/Q2MS3RR7 2115589 Walsh, DA; Moran, HW; Shamblee, DA; Welstead, WJ; Nolan, JC; Sancilio, LF; Graff, G A.H. Robins Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012909&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 15634751 103925159 CHEMBL76451 ZINC26386250 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025800 C[C@@]1(CC=C2C(CCC3[C@](C)(CC(=O)NS(=O)(=O)c4ccc(I)cc4)CCC[C@@]23C)C1)C=C InChI=1S/C27H36INO3S/c1-5-25(2)16-13-22-19(17-25)7-12-23-26(3,14-6-15-27(22,23)4)18-24(30)29-33(31,32)21-10-8-20(28)9-11-21/h5,8-11,13,19,23H,1,6-7,12,14-18H2,2-4H3,(H,29,30)/t19?,23?,25-,26-,27-/m0/s1 IQHMKFJZOGUQIL-MEVFAHFPSA-N 50148381 4-Iodo-N-[2-((1S,4aR,7S)-1,4a,7-trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-acetyl]-benzenesulfonamide::CHEMBL323849 Prostaglandin G/H synthase 2 Ovis aries 72200 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148381&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9916297 104036706 CHEMBL323849 ZINC27094907 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025801 C[C@@]1(CC=C2C(CCC3[C@](C)(CCCC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C23H36O2/c1-5-21(2)15-11-18-17(16-21)9-10-19-22(3,12-6-8-20(24)25)13-7-14-23(18,19)4/h5,11,17,19H,1,6-10,12-16H2,2-4H3,(H,24,25)/t17?,19?,21-,22+,23-/m0/s1 SULJGIKDKXUDLN-LDNYZGLHSA-N 50097207 4-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-butyric acid::CHEMBL117635 Prostaglandin G/H synthase 2 Ovis aries 49400 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097207&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9798239 103994539 CHEMBL117635 ZINC27101320 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025802 C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)\C=C\C=C\C(O)=O)C1)C=C InChI=1S/C24H34O2/c1-5-22(2)16-12-19-18(17-22)10-11-20-23(3,13-7-6-9-21(25)26)14-8-15-24(19,20)4/h5-7,9,12-13,18,20H,1,8,10-11,14-17H2,2-4H3,(H,25,26)/b9-6+,13-7+/t18?,20?,22-,23+,24-/m0/s1 KNBVTHPKILKUNJ-GQHULNROSA-N 50148382 (2E,4E)-5-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-penta-2,4-dienoic acid::CHEMBL118011 Prostaglandin G/H synthase 2 Ovis aries 26800 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148382&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44344142 104036707 CHEMBL118011 ZINC27101383 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025803 C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)C(=O)NN)C1)C=C InChI=1S/C20H32N2O/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(23)22-21/h5,9,14,16H,1,6-8,10-13,21H2,2-4H3,(H,22,23)/t14?,16?,18-,19-,20+/m0/s1 AURNZDRKZMLHPN-BDAJPOSXSA-N 50097201 (1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid hydrazide::CHEMBL116328 Prostaglandin G/H synthase 2 Ovis aries 41900 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097201&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9948850 103994533 CHEMBL116328 ZINC27093364 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025804 C[C@@]1(CC=C2C(CCC3[C@@](C)(CCC[C@@]23C)\C=C\C(O)=O)C1)C=C InChI=1S/C22H32O2/c1-5-20(2)13-9-17-16(15-20)7-8-18-21(3,14-10-19(23)24)11-6-12-22(17,18)4/h5,9-10,14,16,18H,1,6-8,11-13,15H2,2-4H3,(H,23,24)/b14-10+/t16?,18?,20-,21-,22-/m0/s1 FNEDWPSYNFYGHZ-RYRDQYGKSA-N 50148384 (E)-3-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-acrylic acid::CHEMBL117222 Prostaglandin G/H synthase 2 Ovis aries 69700 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148384&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9818831 104036709 CHEMBL117222 ZINC27101268 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025805 C[C@@]1(CC=C2C(CCC3[C@](C)(CCCCC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C24H38O2/c1-5-22(2)16-12-19-18(17-22)10-11-20-23(3,13-7-6-9-21(25)26)14-8-15-24(19,20)4/h5,12,18,20H,1,6-11,13-17H2,2-4H3,(H,25,26)/t18?,20?,22-,23+,24-/m0/s1 IFIXXFKTBDCXOX-OBWQMAAISA-N 50097204 5-((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-pentanoic acid::CHEMBL116532 Prostaglandin G/H synthase 2 Ovis aries 38700 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097204&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9906813 103994536 CHEMBL116532 ZINC27093784 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025806 C[C@@]1(CC=C2C(CCC3[C@](C)(CCC\C=C\C(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C25H38O2/c1-5-23(2)17-13-20-19(18-23)11-12-21-24(3,15-9-16-25(20,21)4)14-8-6-7-10-22(26)27/h5,7,10,13,19,21H,1,6,8-9,11-12,14-18H2,2-4H3,(H,26,27)/b10-7+/t19?,21?,23-,24+,25-/m0/s1 RRWSYMHVTCDSNN-FOGCZXIISA-N 50097197 (E)-6-((1R,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-hex-2-enoic acid::CHEMBL324730 Prostaglandin G/H synthase 2 Ovis aries 37800 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097197&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10361821 103994529 CHEMBL324730 ZINC27097997 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025807 C[C@@]1(CC=C2C(CCC3[C@](C)(C\C=C/C(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C23H34O2/c1-5-21(2)15-11-18-17(16-21)9-10-19-22(3,12-6-8-20(24)25)13-7-14-23(18,19)4/h5-6,8,11,17,19H,1,7,9-10,12-16H2,2-4H3,(H,24,25)/b8-6-/t17?,19?,21-,22+,23-/m0/s1 SPAJNWKSKFFRBI-JGQXIVLHSA-N 50148383 (Z)-4-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-but-2-enoic acid::CHEMBL117478 Prostaglandin G/H synthase 2 Ovis aries 32000 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148383&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44343940 104036708 CHEMBL117478 ZINC27095978 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025808 C[C@@]1(CC=C2C(CCC3[C@](C)(CCC(=O)NS(=O)(=O)c4ccc(I)cc4)CCC[C@@]23C)C1)C=C InChI=1S/C28H38INO3S/c1-5-26(2)17-13-23-20(19-26)7-12-24-27(3,15-6-16-28(23,24)4)18-14-25(31)30-34(32,33)22-10-8-21(29)9-11-22/h5,8-11,13,20,24H,1,6-7,12,14-19H2,2-4H3,(H,30,31)/t20?,24?,26-,27-,28-/m0/s1 IAJJMKMHRGKLOD-OUMCUBCUSA-N 50148380 4-Iodo-N-[3-((1S,4aR,7S)-1,4a,7-trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-propionyl]-benzenesulfonamide::CHEMBL324498 Prostaglandin G/H synthase 2 Ovis aries 60700 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50148380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50148380&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9873351 104036705 CHEMBL324498 ZINC27095944 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025809 C[C@@]1(CC=C2C(CCC3[C@](C)(CC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C21H32O2/c1-5-19(2)12-9-16-15(13-19)7-8-17-20(3,14-18(22)23)10-6-11-21(16,17)4/h5,9,15,17H,1,6-8,10-14H2,2-4H3,(H,22,23)/t15?,17?,19-,20-,21-/m0/s1 JPTYTZASFHUDCV-HQIBCSSTSA-N 50097199 ((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-acetic acid::CHEMBL117763 Prostaglandin G/H synthase 2 Ovis aries 82300 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097199&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9797003 103994531 CHEMBL117763 ZINC27096181 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50025810 C[C@@]1(CC=C2C(CCC3[C@](C)(CCC(O)=O)CCC[C@@]23C)C1)C=C InChI=1S/C22H34O2/c1-5-20(2)13-9-17-16(15-20)7-8-18-21(3,14-10-19(23)24)11-6-12-22(17,18)4/h5,9,16,18H,1,6-8,10-15H2,2-4H3,(H,23,24)/t16?,18?,20-,21-,22-/m0/s1 YVCINYUJSBPRQS-YSDQLLENSA-N 50097210 3-((1S,4aR,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-propionic acid::CHEMBL324837 Prostaglandin G/H synthase 2 Ovis aries 105000 ChEMBL 10.1016/j.bmcl.2004.04.054 10.7270/Q20Z72RM 15177458 Suh, YG; Lee, KO; Moon, SH; Seo, SY; Lee, YS; Kim, SH; Paek, SM; Kim, YH; Lee, YS; Jeong, JM; Lee, SJ; Kim, SG Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097210&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9840502 103994542 CHEMBL324837 ZINC27099287 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50026930 C[C@H](C(O)=O)c1ccc(cc1)-c1ccsc1 InChI=1S/C13H12O2S/c1-9(13(14)15)10-2-4-11(5-3-10)12-6-7-16-8-12/h2-9H,1H3,(H,14,15)/t9-/m0/s1 PFLCZHOSQMPCMN-VIFPVBQESA-N 50452027 CHEMBL2096754 Prostaglandin G/H synthase 2 Ovis aries 179700 ChEMBL 10.1016/j.bmcl.2003.11.066 10.7270/Q25M655Z 15013005 Mittal, S; Malde, A; Selvam, C; Arun, KH; Johar, PS; Jachak, SM; Ramarao, P; Bharatam, PV; Chawla, HP National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452027&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10443945 225145556 CHEMBL2096754 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50027895 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries >430 ChEMBL 10.1016/j.bmcl.2004.01.076 10.7270/Q20P0ZFX 15050636 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50027897 CS(=O)(=O)c1ccc(cc1)C1=C(COC1=O)c1ccc(cc1)S(=O)(=O)[N-][N+]#N InChI=1S/C17H13N3O6S2/c1-27(22,23)13-6-4-12(5-7-13)16-15(10-26-17(16)21)11-2-8-14(9-3-11)28(24,25)20-19-18/h2-9H,10H2,1H3 PDSBJCCQUDPGOK-UHFFFAOYSA-N 50143481 4-[4-(4-Methanesulfonyl-phenyl)-5-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonyl azide::CHEMBL353744 Prostaglandin G/H synthase 2 Ovis aries 3100 ChEMBL 10.1016/j.bmcl.2004.01.076 10.7270/Q20P0ZFX 15050636 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143481&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386714 104032675 CHEMBL353744 ZINC28094703 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50027899 CC(=O)NS(=O)(=O)c1ccc(cc1)C1=C(COC1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H17NO7S2/c1-12(21)20-29(25,26)16-9-5-14(6-10-16)18-17(11-27-19(18)22)13-3-7-15(8-4-13)28(2,23)24/h3-10H,11H2,1-2H3,(H,20,21) RLCZTSJLSWOTKF-UHFFFAOYSA-N 50143484 CHEMBL368597::N-Acetyl-4-[4-(4-methanesulfonyl-phenyl)-2-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonamide Prostaglandin G/H synthase 2 Ovis aries 4600 ChEMBL 10.1016/j.bmcl.2004.01.076 10.7270/Q20P0ZFX 15050636 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143484&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386776 104032678 CHEMBL368597 ZINC28106439 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50027901 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccc(cc1)S(=O)(=O)[N-][N+]#N InChI=1S/C17H13N3O6S2/c1-27(22,23)13-6-2-11(3-7-13)15-10-26-17(21)16(15)12-4-8-14(9-5-12)28(24,25)20-19-18/h2-9H,10H2,1H3 OTUPJNOZLMPCEK-UHFFFAOYSA-N 50143485 4-[4-(4-Methanesulfonyl-phenyl)-2-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonyl azide::CHEMBL366723 Prostaglandin G/H synthase 2 Ovis aries 11000 ChEMBL 10.1016/j.bmcl.2004.01.076 10.7270/Q20P0ZFX 15050636 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143485&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386666 104032679 CHEMBL366723 ZINC28086152 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50027903 CC(=O)NS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H17NO7S2/c1-12(21)20-29(25,26)16-9-3-13(4-10-16)17-11-27-19(22)18(17)14-5-7-15(8-6-14)28(2,23)24/h3-10H,11H2,1-2H3,(H,20,21) BRCUVPAXYQULRV-UHFFFAOYSA-N 50143486 CHEMBL366422::N-Acetyl-4-[4-(4-methanesulfonyl-phenyl)-5-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonamide Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1016/j.bmcl.2004.01.076 10.7270/Q20P0ZFX 15050636 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143486&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10003092 104032680 CHEMBL366422 ZINC28089817 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50027905 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C17H15NO6S2/c1-25(20,21)13-6-2-11(3-7-13)15-10-24-17(19)16(15)12-4-8-14(9-5-12)26(18,22)23/h2-9H,10H2,1H3,(H2,18,22,23) KGSKTOKRYIPXDG-UHFFFAOYSA-N 50143482 4-[4-(4-Methanesulfonyl-phenyl)-2-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonamide::CHEMBL368407 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2004.01.076 10.7270/Q20P0ZFX 15050636 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143482&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386669 104032676 CHEMBL368407 ZINC28021627 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50027908 CS(=O)(=O)c1ccc(cc1)C1=C(COC1=O)c1ccc(cc1)S(N)(=O)=O InChI=1S/C17H15NO6S2/c1-25(20,21)13-6-4-12(5-7-13)16-15(10-24-17(16)19)11-2-8-14(9-3-11)26(18,22)23/h2-9H,10H2,1H3,(H2,18,22,23) CARPFYSHHSHYMZ-UHFFFAOYSA-N 50143483 4-[4-(4-Methanesulfonyl-phenyl)-5-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonamide::CHEMBL177972 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2004.01.076 10.7270/Q20P0ZFX 15050636 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143483&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386775 104032677 CHEMBL177972 ZINC28106433 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065527 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065529 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccc(Cl)cc1)\c1ccccc1 InChI=1S/C21H17ClO2S/c1-25(23,24)20-13-9-18(10-14-20)21(17-5-3-2-4-6-17)15-16-7-11-19(22)12-8-16/h2-15H,1H3/b21-15+ SSJFWOVZCDSXFK-RCCKNPSSSA-N 50158193 1-chloro-4-{(E)-2-[4-(methylsulfonyl)phenyl]-2-phenylvinyl}benzene::CHEMBL360310 Prostaglandin G/H synthase 2 Ovis aries 114 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158193&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388916 104044978 CHEMBL360310 ZINC28124460 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065531 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccc(F)c(F)c1)\c1ccccc1 InChI=1S/C21H16F2O2S/c1-26(24,25)18-10-8-17(9-11-18)19(16-5-3-2-4-6-16)13-15-7-12-20(22)21(23)14-15/h2-14H,1H3/b19-13+ YRBVPLSHFFJSHS-CPNJWEJPSA-N 50158190 1,2-Difluoro-4-[2-(4-methanesulfonyl-phenyl)-2-phenyl-vinyl]-benzene::CHEMBL426955 Prostaglandin G/H synthase 2 Ovis aries 790 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158190&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388897 104044975 CHEMBL426955 ZINC28122813 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065541 Cc1ccc(cc1)C(=Cc1ccc(cc1)S(C)(=O)=O)c1ccc(C)cc1 InChI=1S/C23H22O2S/c1-17-4-10-20(11-5-17)23(21-12-6-18(2)7-13-21)16-19-8-14-22(15-9-19)26(3,24)25/h4-16H,1-3H3 RAQUSUKRSYUEMK-UHFFFAOYSA-N 50158194 1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL179204 Prostaglandin G/H synthase 2 Ovis aries 31000 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158194&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388920 104044979 CHEMBL179204 ZINC28118396 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065548 CS(=O)(=O)c1ccc(C=C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1 InChI=1S/C21H16Cl2O2S/c1-26(24,25)20-12-2-15(3-13-20)14-21(16-4-8-18(22)9-5-16)17-6-10-19(23)11-7-17/h2-14H,1H3 QZMXDJPBJZDNMK-UHFFFAOYSA-N 50158189 1-[2,2-bis(4-chlorophenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL361848 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158189&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388811 104044974 CHEMBL361848 ZINC28120468 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065577 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccc(F)cc1)\c1ccccc1 InChI=1S/C21H17FO2S/c1-25(23,24)20-13-9-18(10-14-20)21(17-5-3-2-4-6-17)15-16-7-11-19(22)12-8-16/h2-15H,1H3/b21-15+ BDWYSYFYONHNGL-RCCKNPSSSA-N 50158187 1-fluoro-4-{(E)-2-[4-(methylsulfonyl)phenyl]-2-phenylvinyl}benzene::CHEMBL360720 Prostaglandin G/H synthase 2 Ovis aries 32 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158187&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11291120 104044972 CHEMBL360720 ZINC28126591 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065581 Cc1ccc(\C=C(/c2ccccc2)c2ccc(cc2)S(C)(=O)=O)cc1 InChI=1S/C22H20O2S/c1-17-8-10-18(11-9-17)16-22(19-6-4-3-5-7-19)20-12-14-21(15-13-20)25(2,23)24/h3-16H,1-2H3/b22-16+ OKYHBSFDSASVNT-CJLVFECKSA-N 50158191 1-methyl-4-{(E)-2-[4-(methylsulfonyl)phenyl]-2-phenylvinyl}benzene::CHEMBL178356 Prostaglandin G/H synthase 2 Ovis aries 1200 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158191&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388872 104044976 CHEMBL178356 ZINC28123193 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065591 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccccc1)\c1ccccc1 InChI=1S/C21H18O2S/c1-24(22,23)20-14-12-19(13-15-20)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-16H,1H3/b21-16+ ZPQRRDVDLPNHQM-LTGZKZEYSA-N 50158188 1-(1,2-Diphenyl-vinyl)-4-methanesulfonyl-benzene::CHEMBL178355 Prostaglandin G/H synthase 2 Ovis aries 130 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158188&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388871 104044973 CHEMBL178355 ZINC28123186 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065594 CS(=O)(=O)c1ccc(C=C(c2ccc(F)cc2)c2ccc(F)cc2)cc1 InChI=1S/C21H16F2O2S/c1-26(24,25)20-12-2-15(3-13-20)14-21(16-4-8-18(22)9-5-16)17-6-10-19(23)11-7-17/h2-14H,1H3 AAXDKCSQCFEDKK-UHFFFAOYSA-N 50158192 1-[2,2-bis(4-fluorophenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL179723 Prostaglandin G/H synthase 2 Ovis aries 32000 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158192&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388803 104044977 CHEMBL179723 ZINC28120617 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50065596 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50079155 O=C1CC(Nc2ccccc2Nc2ccc(nn2)N2CCCCC2)=NN1 InChI=1S/C18H21N7O/c26-18-12-16(22-24-18)20-14-7-3-2-6-13(14)19-15-8-9-17(23-21-15)25-10-4-1-5-11-25/h2-3,6-9H,1,4-5,10-12H2,(H,19,21)(H,20,22)(H,24,26) VJCJIBKNIYAJEJ-UHFFFAOYSA-N 50001211 CHEMBL3236731 Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmc.2014.02.042 10.7270/Q2VM4DRX 24631365 Khalil, NA; Ahmed, EM; Mohamed, KO; Nissan, YM; Zaitone, SA Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001211&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90654422 242055934 CHEMBL3236731 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50079156 O=C1CC(Nc2ccccc2Nc2ccc(nn2)N2CCOCC2)=NN1 InChI=1S/C17H19N7O2/c25-17-11-15(21-23-17)19-13-4-2-1-3-12(13)18-14-5-6-16(22-20-14)24-7-9-26-10-8-24/h1-6H,7-11H2,(H,18,20)(H,19,21)(H,23,25) OVBXTCFARXRFSK-UHFFFAOYSA-N 50001212 CHEMBL3236732 Prostaglandin G/H synthase 2 Ovis aries 390 ChEMBL 10.1016/j.bmc.2014.02.042 10.7270/Q2VM4DRX 24631365 Khalil, NA; Ahmed, EM; Mohamed, KO; Nissan, YM; Zaitone, SA Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001212&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90654423 242055935 CHEMBL3236732 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50079157 Clc1ccccc1Nc1ccc(Nc2ccccc2NC2=NNC(=O)C2)nn1 InChI=1S/C19H16ClN7O/c20-12-5-1-2-6-13(12)21-16-9-10-17(25-24-16)22-14-7-3-4-8-15(14)23-18-11-19(28)27-26-18/h1-10H,11H2,(H,21,24)(H,22,25)(H,23,26)(H,27,28) UQIVJMGZEVNQOP-UHFFFAOYSA-N 50001213 CHEMBL3236733 Prostaglandin G/H synthase 2 Ovis aries 720 ChEMBL 10.1016/j.bmc.2014.02.042 10.7270/Q2VM4DRX 24631365 Khalil, NA; Ahmed, EM; Mohamed, KO; Nissan, YM; Zaitone, SA Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001213&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90654424 103915678 CHEMBL3236733 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50079158 Clc1ccc(Nc2ccc(Nc3ccccc3NC3=NNC(=O)C3)nn2)cc1 InChI=1S/C19H16ClN7O/c20-12-5-7-13(8-6-12)21-16-9-10-17(25-24-16)22-14-3-1-2-4-15(14)23-18-11-19(28)27-26-18/h1-10H,11H2,(H,21,24)(H,22,25)(H,23,26)(H,27,28) VIDOLFNUPIHOTH-UHFFFAOYSA-N 50001222 CHEMBL3236734 Prostaglandin G/H synthase 2 Ovis aries 840 ChEMBL 10.1016/j.bmc.2014.02.042 10.7270/Q2VM4DRX 24631365 Khalil, NA; Ahmed, EM; Mohamed, KO; Nissan, YM; Zaitone, SA Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001222&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90654425 103915687 CHEMBL3236734 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50079159 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 220 ChEMBL 10.1016/j.bmc.2014.02.042 10.7270/Q2VM4DRX 24631365 Khalil, NA; Ahmed, EM; Mohamed, KO; Nissan, YM; Zaitone, SA Cairo University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096631 COCOc1cccc2cc(C)c(C(C)=O)c(O)c12 InChI=1S/C15H16O4/c1-9-7-11-5-4-6-12(19-8-18-3)14(11)15(17)13(9)10(2)16/h4-7,17H,8H2,1-3H3 QGVYDKLTHVYTBB-UHFFFAOYSA-N 50015225 CHEMBL3262706 Prostaglandin G/H synthase 2 Ovis aries 19010 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015225&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656717 103927058 CHEMBL3262706 ZINC05999160 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096632 CC(=O)c1c(C)cc2cccc(OCc3ccccc3)c2c1O InChI=1S/C20H18O3/c1-13-11-16-9-6-10-17(19(16)20(22)18(13)14(2)21)23-12-15-7-4-3-5-8-15/h3-11,22H,12H2,1-2H3 IXEYQUSXXQRNNI-UHFFFAOYSA-N 50015226 CHEMBL3262708 Prostaglandin G/H synthase 2 Ovis aries 11210 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015226&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656718 103927059 CHEMBL3262708 ZINC06092496 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096633 CC(=O)c1c(C)cc2cccc(OCc3ccccc3Br)c2c1O InChI=1S/C20H17BrO3/c1-12-10-14-7-5-9-17(19(14)20(23)18(12)13(2)22)24-11-15-6-3-4-8-16(15)21/h3-10,23H,11H2,1-2H3 KYYFKELCZZHVQQ-UHFFFAOYSA-N 50015227 CHEMBL3262710 Prostaglandin G/H synthase 2 Ovis aries 12170 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015227&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656719 103927060 CHEMBL3262710 ZINC06092493 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096634 CC(=O)c1c(C)cc2cccc(OCc3cccc(Cl)c3)c2c1O InChI=1S/C20H17ClO3/c1-12-9-15-6-4-8-17(19(15)20(23)18(12)13(2)22)24-11-14-5-3-7-16(21)10-14/h3-10,23H,11H2,1-2H3 VTDSAQPXSGERTE-UHFFFAOYSA-N 50015228 CHEMBL3262712 Prostaglandin G/H synthase 2 Ovis aries 14230 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015228&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656720 103927061 CHEMBL3262712 ZINC27440320 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096635 Cc1cc(OCC=C)c2C(=O)c3c(OCC=C)cccc3C(=O)c2c1 InChI=1S/C21H18O4/c1-4-9-24-16-8-6-7-14-18(16)21(23)19-15(20(14)22)11-13(3)12-17(19)25-10-5-2/h4-8,11-12H,1-2,9-10H2,3H3 KVSAAEUTDHLDDO-UHFFFAOYSA-N 50015229 CHEMBL3262717 Prostaglandin G/H synthase 2 Ovis aries 11640 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015229&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656721 103927062 CHEMBL3262717 ZINC03785156 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096636 Cc1cc(OCc2ccccc2)c2C(=O)c3c(OCc4ccccc4)cccc3C(=O)c2c1 InChI=1S/C29H22O4/c1-19-15-23-27(25(16-19)33-18-21-11-6-3-7-12-21)29(31)26-22(28(23)30)13-8-14-24(26)32-17-20-9-4-2-5-10-20/h2-16H,17-18H2,1H3 DFRILRPWLNNNDA-UHFFFAOYSA-N 50015230 CHEMBL3262718 Prostaglandin G/H synthase 2 Ovis aries 20010 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015230&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656722 103927063 CHEMBL3262718 ZINC05161687 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096637 Cc1cc(OCc2ccc(I)cc2)c2C(=O)c3c(OCc4ccc(I)cc4)cccc3C(=O)c2c1 InChI=1S/C29H20I2O4/c1-17-13-23-27(25(14-17)35-16-19-7-11-21(31)12-8-19)29(33)26-22(28(23)32)3-2-4-24(26)34-15-18-5-9-20(30)10-6-18/h2-14H,15-16H2,1H3 MJUWTLQYFCGJGC-UHFFFAOYSA-N 50015231 CHEMBL3262720 Prostaglandin G/H synthase 2 Ovis aries 16810 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015231&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656723 103927064 CHEMBL3262720 ZINC06092495 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096638 CC(=O)c1c(C)cc2cccc(O)c2c1O InChI=1S/C13H12O3/c1-7-6-9-4-3-5-10(15)12(9)13(16)11(7)8(2)14/h3-6,15-16H,1-2H3 DMLHPCALHMPJHS-UHFFFAOYSA-N 50015232 CHEBI:7520::NEPODIN Prostaglandin G/H synthase 2 Ovis aries 32280 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015232&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 100780 103927065 C09954 ZINC01552536 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096639 Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1 InChI=1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3 LQGUBLBATBMXHT-UHFFFAOYSA-N 50455992 CHEBI:3687::Chrysophanol Prostaglandin G/H synthase 2 Ovis aries 36120 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455992&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10208 225146908 C10315 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096640 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries >30000 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50096641 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 150 ChEMBL 10.1016/j.ejmech.2014.04.033 10.7270/Q2D22051 24763362 Grover, J; Kumar, V; Singh, V; Bairwa, K; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095711 Clc1cccc(Cl)c1Nc1ccccc1Cc1nn(CN2CCOCC2)c(=S)o1 InChI=1S/C20H20Cl2N4O2S/c21-15-5-3-6-16(22)19(15)23-17-7-2-1-4-14(17)12-18-24-26(20(29)28-18)13-25-8-10-27-11-9-25/h1-7,23H,8-13H2 VKEAJEPLJIBNFA-UHFFFAOYSA-N 50014162 CHEMBL3260859 Prostaglandin G/H synthase 2 Ovis aries 15000 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014162&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656499 103926184 CHEMBL3260859 ZINC26653554 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095712 Clc1cccc(Cl)c1Nc1ccccc1Cc1nn(CN2CCCCC2)c(=S)o1 InChI=1S/C21H22Cl2N4OS/c22-16-8-6-9-17(23)20(16)24-18-10-3-2-7-15(18)13-19-25-27(21(29)28-19)14-26-11-4-1-5-12-26/h2-3,6-10,24H,1,4-5,11-14H2 IOIYMIJFZBAFTJ-UHFFFAOYSA-N 50014163 CHEMBL3260860 Prostaglandin G/H synthase 2 Ovis aries 15000 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014163&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656500 103926185 CHEMBL3260860 ZINC26652886 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095713 CN1CCN(Cn2nc(Cc3ccccc3Nc3c(Cl)cccc3Cl)oc2=S)CC1 InChI=1S/C21H23Cl2N5OS/c1-26-9-11-27(12-10-26)14-28-21(30)29-19(25-28)13-15-5-2-3-8-18(15)24-20-16(22)6-4-7-17(20)23/h2-8,24H,9-14H2,1H3 YVKSIINQVAYIQG-UHFFFAOYSA-N 50014165 CHEMBL3260862 Prostaglandin G/H synthase 2 Ovis aries 14500 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014165&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656501 103926187 CHEMBL3260862 ZINC26646238 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095714 CCN1CCN(Cn2nc(Cc3ccccc3Nc3c(Cl)cccc3Cl)oc2=S)CC1 InChI=1S/C22H25Cl2N5OS/c1-2-27-10-12-28(13-11-27)15-29-22(31)30-20(26-29)14-16-6-3-4-9-19(16)25-21-17(23)7-5-8-18(21)24/h3-9,25H,2,10-15H2,1H3 JWXZCEDDPQFPQQ-UHFFFAOYSA-N 50014166 CHEMBL3260863 Prostaglandin G/H synthase 2 Ovis aries 12500 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014166&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656502 103926188 CHEMBL3260863 ZINC26651970 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095715 Clc1cccc(Cl)c1Nc1ccccc1Cc1nn(CN2CCNCC2)c(=S)o1 InChI=1S/C20H21Cl2N5OS/c21-15-5-3-6-16(22)19(15)24-17-7-2-1-4-14(17)12-18-25-27(20(29)28-18)13-26-10-8-23-9-11-26/h1-7,23-24H,8-13H2 LYVTZCGGMMILJC-UHFFFAOYSA-N 50014167 CHEMBL3260864 Prostaglandin G/H synthase 2 Ovis aries 12000 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014167&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656503 103926189 CHEMBL3260864 ZINC26651646 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095716 Clc1cccc(Cl)c1Nc1ccccc1Cc1nn(CNC2CCCCC2)c(=S)o1 InChI=1S/C22H24Cl2N4OS/c23-17-10-6-11-18(24)21(17)26-19-12-5-4-7-15(19)13-20-27-28(22(30)29-20)14-25-16-8-2-1-3-9-16/h4-7,10-12,16,25-26H,1-3,8-9,13-14H2 LVFQIBCYIICVLI-UHFFFAOYSA-N 50014168 CHEMBL3260867 Prostaglandin G/H synthase 2 Ovis aries 10500 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014168&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656504 103926190 CHEMBL3260867 ZINC26656108 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095717 Clc1ccccc1NCn1nc(Cc2ccccc2Nc2c(Cl)cccc2Cl)oc1=S InChI=1S/C22H17Cl3N4OS/c23-15-7-2-4-11-19(15)26-13-29-22(31)30-20(28-29)12-14-6-1-3-10-18(14)27-21-16(24)8-5-9-17(21)25/h1-11,26-27H,12-13H2 MOMKOOVUTOVGDI-UHFFFAOYSA-N 50014169 CHEMBL3260868 Prostaglandin G/H synthase 2 Ovis aries 13000 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014169&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656505 103926191 CHEMBL3260868 ZINC26655529 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095718 Clc1cccc(NCn2nc(Cc3ccccc3Nc3c(Cl)cccc3Cl)oc2=S)c1 InChI=1S/C22H17Cl3N4OS/c23-15-6-3-7-16(12-15)26-13-29-22(31)30-20(28-29)11-14-5-1-2-10-19(14)27-21-17(24)8-4-9-18(21)25/h1-10,12,26-27H,11,13H2 VJDKRXXRVLAOCJ-UHFFFAOYSA-N 50014170 CHEMBL3260869 Prostaglandin G/H synthase 2 Ovis aries 9000 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014170&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 90656506 103926192 CHEMBL3260869 ZINC26655836 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095719 OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) DCOPUUMXTXDBNB-UHFFFAOYSA-N 13066 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid::CHEMBL139::Diclofenac::US11337935, Compound Diclofenac::US11478464, Compound Diclofenac::{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid Prostaglandin G/H synthase 2 Ovis aries 15000 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13066&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search DIF 1NR6,5U1R,3N8Y,1SV9,3CFQ,4OJ4,4XTA,2WEK,1DVX,8BSG,1PXX,5DBY,2B17,3IB0,4ZBQ,4ZBR,4Z69,4UBS,6HN0,6HN1 3033 46513484 47381 CHEMBL139 DB00586 2714 C01690 ZINC00001281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50095721 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 40 ChEMBL 10.1016/j.bmc.2014.03.043 10.7270/Q26H4JXW 24751552 Palkar, MB; Singhai, AS; Ronad, PM; Vishwanathswamy, AH; Boreddy, TS; Veerapur, VP; Shaikh, MS; Rane, RA; Karpoormath, R K.L.E.U's College of Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50107116 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1021/jm970034q 10.7270/Q2JD4VW7 9484493 Hopper, AT; Witiak, DT; Ziemniak, J OXIS International, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50107123 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 660000 ChEMBL 10.1021/jm970034q 10.7270/Q2JD4VW7 9484493 Hopper, AT; Witiak, DT; Ziemniak, J OXIS International, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182490 CC\C=C/C\C=C/C\C=C/C\C=C/CCSCCCC(O)=O InChI=1S/C19H30O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-22-18-15-16-19(20)21/h3-4,6-7,9-10,12-13H,2,5,8,11,14-18H2,1H3,(H,20,21)/b4-3-,7-6-,10-9-,13-12- JUGSAWFPXQSLMJ-LTKCOYKYSA-N 50242353 5-thia-8,11,14,17-eicosatetraenoic acid::CHEMBL460444 Prostaglandin G/H synthase 2 Ovis aries 3900 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242353&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10019057 104099040 CHEMBL460444 ZINC34093174 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182491 CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15- JAZBEHYOTPTENJ-JLNKQSITSA-N 50242349 (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaenoic acid::(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoic acid::(all-Z)-5,8,11,14,17-eicosapentaenoic acid::5,8,11,14,17-EICOSAPENTAENOIC ACID::5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid::CHEMBL460026::EPA::ICOSAPENT ETHYL::Icosapent::Timnodonic acid::all-cis-icosa-5,8,11,14,17-pentaenoic acid::cis-5,8,11,14,17-eicosapentaenoic acid::cis-Delta(5,8,11,14,17)-eicosapentaenoic acid::omega-3-Eicosapentaenoic Acid::vascepa Prostaglandin G/H synthase 2 Ovis aries 7100 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242349&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search EPA 3GWX,8ID9,6LXA,7BQ4,3HS6,1IGX,5M0O,7WOM 446284 104099038 28364 CHEMBL460026 DB00159 3362 C06428 ZINC04474603 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182492 CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O InChI=1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18- MBMBGCFOFBJSGT-KUBAVDMBSA-N 50210259 (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid::(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid (F4)::CHEMBL367149::DHA::Doconexent::all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Prostaglandin G/H synthase 2 Ovis aries 9800 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210259&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search F22 445580 104086818 28125 CHEMBL367149 C06429 ZINC04474564 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182493 CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-4,6-7,9-10H,2,5,8,11-17H2,1H3,(H,19,20)/b4-3-,7-6-,10-9- DTOSIQBPPRVQHS-PDBXOOCHSA-N 50240347 (9,12,15)-linolenic acid::(9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid::(Z,Z,Z)-9,12,15-octadecatrienoic acid::9-cis,12-cis,15-cis-octadecatrienoic acid::ALA::CHEMBL8739::all-cis-9,12,15-octadecatrienoic acid::alpha-linolenic acid::cid_5280934::cis,cis,cis-9,12,15-octadecatrienoic acid::cis-Delta(9,12,15)-octadecatrienoic acid::linolenic acid Prostaglandin G/H synthase 2 Ovis aries 12000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240347&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search LNL 7FFX,2BYO,1FK6,4E1G 5280934 104098240 27432 CHEMBL8739 DB00132 1049 C06427 ZINC03802189 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182501 CCCCC\C=C/C\C=C/CCCCCCCC(O)=O InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9- OYHQOLUKZRVURQ-HZJYTTRNSA-N 22231 (9Z,12Z)-octadeca-9,12-dienoic acid::CHEMBL267476::Linoleic Acid::Linoleic acid (LA) Prostaglandin G/H synthase 2 Ovis aries 94000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22231&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search EIC 4LKT,8H14,7ZH1,7ODL,7OD3,7XU2,7XU0,7XU1,7XU4,5BVS,2Q9S,4NYQ,7ZH2,7WGV,6CNG,2EVL,4DQ4,7JJI,8H0Z,7CN8,6ZP2,7DWY,7X08,7WDJ,6OGH,8ID4,1IGZ,6ZB4,6ZB5,8H0X,8H0Y,7QUS,7QUR,8H10,5Z0B,7XTZ,4IA6 5280450 49846046 17351 CHEMBL267476 1052 C01595 ZINC04474613 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182502 CC\C=C/C\C=C/C\C=C/CC\C=C\CSCCCC(O)=O InChI=1S/C19H30O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-22-18-15-16-19(20)21/h3-4,6-7,9-10,13-14H,2,5,8,11-12,15-18H2,1H3,(H,20,21)/b4-3-,7-6-,10-9-,14-13+ PFXIXAVMUKVROB-TWMAVKMASA-N 50242355 (7E,11Z,14Z,17Z)-5-thiaeicosa-7,11,14,17-tetraenoic acid::CHEMBL541729 Prostaglandin G/H synthase 2 Ovis aries 120000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242355&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44559942 104099042 CHEMBL541729 ZINC40392562 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182503 CC\C=C/C\C=C/C\C=C/C\C=C/CCSCC(O)=O InChI=1S/C17H26O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20-16-17(18)19/h3-4,6-7,9-10,12-13H,2,5,8,11,14-16H2,1H3,(H,18,19)/b4-3-,7-6-,10-9-,13-12- KBTOOHDAHNWJDH-LTKCOYKYSA-N 50242352 3-thia-6,9,12,15-octadecatetraenoic acid::CHEMBL447250 Prostaglandin G/H synthase 2 Ovis aries 160000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242352&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44559940 104099039 CHEMBL447250 ZINC40834801 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182505 CC\C=C/C\C=C/C\C=C/C\C=C/CC\C=C\COCC(O)=O InChI=1S/C20H30O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-19-20(21)22/h3-4,6-7,9-10,12-13,16-17H,2,5,8,11,14-15,18-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,17-16+ HYRVVXJWCJCBMU-IIFHDYRKSA-N 50242357 (5E,9Z,12Z,15Z,18Z)-3-oxaheneicosa-5,9,12,15,18-pentaenoic acid::CHEMBL460655 Prostaglandin G/H synthase 2 Ovis aries 180000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242357&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44559944 104099044 CHEMBL460655 ZINC40865975 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182506 CCCCCCCC\C=C/CCCCCCCC(O)=O InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9- ZQPPMHVWECSIRJ-KTKRTIGZSA-N 50150484 (Z)-9-octadecenoic acid::(Z)-Octadec-9-enoic acid::CHEMBL8659::OLEATE::Octadec-9-enoic acid::oleaic acid::oleicacid Prostaglandin G/H synthase 2 Ovis aries >500000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150484&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search OLA 1VYF,4JKV,7CRL,7CRI,7CRJ,7CRK,7CRT,7CRS,7CRX,7CRY,4ZJ8,4ZJC,7URD,7FEE,5OM1,5OM4,2FTB,6JYF,5G28,1DKF,4U9N,4X6D,5WIV,5WIU,5NLX,6SU4,6SU3,7BMH,4NYQ,7W7H,3V2R,6PT2,3NY8,7URA,6E12,6ABA,6YT4,7A4P,6C1R,7Z0D,6D26,6D27,5LWY,5OLV,5OLZ,5OLG,5OLH,5OLO,4EA3,6KS1,5DHH,5DHG,7Z09,7SR8,4X5M,6VUM,4Z9G,5NM4,5NM2,1HMS,6WQA,5CGD,5CGC,6LX8,7ZN9,7ZN8,7ZN0,7ZN3,7ZNI,7ZNH,6W25,5ZTY,5ZTL,5ZTK,5UIW,5EE7,3PGU,7ZNE,7ZND,7ZNG,7ZNA,7ZNC,7ZNB,6XYT,2EV1,2EV3,2EV2,2EV4,4DQ3,6XBW,5TGZ,6WGT,6ZG4,7QAA,5DSG,1FE3,6TPG,6TPJ,6TPN,3WEB,4LUR,6BD4,5VRA,7N6R,4N6H,2WQ9,2WQA,3VKK,5G2C,6KQI,1LID,5JTB,6GT3,7O8N,7ZLY,6BQH,6WH4,1ICN,5LXA,5VEW,6ZFZ,4RWD,4S0V,5CE4,1G74,4EIY,7ZL9,3X3B,3X3C,7Z0A,6MXT,6FFH,6FFI,8CU6,8CU7,6KRZ,6M9T,8FYN,4KPP,7T71,5EPQ,2LKK,7WE5,7Q38,7Q35,5MZJ,7OTS,7PX4,4X9X,6MD4,6MD1,6MD0,4NC3,7K15,7ARO,6O1T,1J78,1J7E,6ZDR,6ZDV,5G2D,2JU8,2E9L,2E9M,5LX9,7JNI,6JZH,6V9S,7V3K,6ZG9,7PYR,6ME3,5WS3,7N6Q,6I9F,6RZ8,6RZ9,6RZ6,6RZ7,6RZ4,6RZ5,7YXA,3O19,2MO5,5FJG,5LWE,5UVI,6JY7,6JY6,6JY9,6JY8,6JYE,6JYD,6JYC,6JYB,6JYA,3UG9,5IUA,5IUB,5IU4,5IU7,5IU8,1LFO,6AB9,6ME5,6ME2,8ID6,6S0Q,1GT6,2AF9,6YX9,6YXG,6YXF,6YXD,7AKX,5G54,6OL9,5K2D,5K2B,5K2C,5K2A,5XRA,7ZOV,7ZOW,7ZOU,7ZOY,6FJ3,1GNI,4K5Y,4YZI,7KAY,7KAZ,7WZM,6HLP,6HLO,4OR2,7O8V,7O8T,7O8U,7O8R,7O8S,7O8P,7O8Q,7O8Z,7O8Y,7O8F,7O8G,7O8O,7O8L,7O8M,7O8J,7O8K,7O8H,7O8I,6PS3,6PS2,6PS1,6PS0,6PS7,6PS6,6PS5,6PS4,4IKX,4IKY,4IKV,4IKW,2AG4,1FK5,2FLJ,6DJ6,5UEN,5WQC,7KHR,4U4T,4U4W,4U4V,6B73,5UNG,7SQO,1SX6,3LSP,6PRZ,6AQF,6YC2,6YC0,6YC4,8DU3,5N2R,7Z0C,3ODU,7ZMY,3O22,3O2Y,4OO9,6CSM,6CSN,6CSO,5O9H,1PMP,5MZP,2AG2,6KUX,6KUW,6S0L,5GLI,6CM4,6GPX,2ZOX,6K6K,6K6J,6K6I,6LUQ,6ZZX,6ZZY,4IB4,6DRY,6DRZ 445639 104038909 16196 CHEMBL8659 DB06689 1054 C00712 ZINC06845860 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182507 CCCCCCCCCCCCCCCCCC(O)=O InChI=1S/C18H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H,19,20) QIQXTHQIDYTFRH-UHFFFAOYSA-N 50240485 18:0::C18:0::CH3-[CH2]16-COOH::CHEMBL46403::Octadecanoic acid::Octadecansaeure::Oktadekansaeure::Stearinsaeure::acide octadecanoique::acide stearique::n-octadecanoic acid::octadecoic acid::stearic acid Prostaglandin G/H synthase 2 Ovis aries >500000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240485&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search STE 3WXQ,7R36,7R34,7R35,7R33,4OSD,5C9J,3WVM,3V2P,7RF1,3NYI,4JJ2,6W1O,6W1V,6W1T,6W1R,6W1P,6W1Q,1E7I,6KSM,7Q4J,1HMT,1K4W,6LX7,4RC8,5K53,4FNN,1UVC,3EML,6YRX,6YRZ,6YRU,6YRV,2ZYI,1LIF,6YS2,6YS1,8EZ5,3UEX,8F4J,8F4K,8F4H,8F4I,8F4F,8F4G,8F4D,8F4C,5UWZ,3CJD,4TW3,6T4C,7Z3Z,7QW9,4GF9,6ZH7,7FD2,6P1Z,6W1U,7RJI,1XXS,1FK4,4JIV,6T40,6T48,7RF8,7RF5,7RF4,7RF7,7RF6,7RF3,7RF2,4WBK,2FVA,4KU0,7AV4,5C8C,3FLV,8F4E,3VG9,2WH5,6P2A,6P20,6P22 5281 104098316 28842 CHEMBL46403 DB03193 3377 C01530 ZINC04978673 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182508 CCCCCCCCCCCCCCCC(O)=O InChI=1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18) IPCSVZSSVZVIGE-UHFFFAOYSA-N 50152850 1-HEXYLDECANOIC ACID::CHEMBL82293::Hexadecanoic acid::Hexadecanoic acid anion::Palmitic acid (PA) Prostaglandin G/H synthase 2 Ovis aries >500000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152850&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search FAT 985 104040857 15756 CHEMBL82293 DB03796 1055 C00249 ZINC06072466 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182509 CCCCCCCCCCCCCCC(O)=O InChI=1S/C15H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(16)17/h2-14H2,1H3,(H,16,17) WQEPLUUGTLDZJY-UHFFFAOYSA-N 50242348 CHEMBL460025::pentadecanoic acid Prostaglandin G/H synthase 2 Ovis aries >500000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242348&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search F15 1XVP,1XV9,6GFS,6EOP,7WPW,4Z69 13849 104099037 42504 CHEMBL460025 C16537 ZINC30731069 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182510 CCCCCCCCCCCCCC(O)=O InChI=1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16) TUNFSRHWOTWDNC-UHFFFAOYSA-N 50147581 1-tridecanecarboxylic acid::14:0::CH3-[CH2]12-COOH::CHEMBL111077::Myristinsaeure::acide tetradecanoique::myristic acid::n-Tetradecan-1-oic acid::n-Tetradecoic acid::n-tetradecanoic acid::tetradecoic acid Prostaglandin G/H synthase 2 Ovis aries >500000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50147581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50147581&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search MYR 1VBC,1VBA,1H8T,4GB3,1XDA,1HBK,6O6O,6THN,6THD,7AAE,8A9Q,3EE4,1BKE,4Q4Y,5FVN,4X6R,7WT3,6VVQ,2AG9,1UPH,4HPU,3FXI,7PN6,3V2N,1AL2,4L8U,4LB9,7VR9,1IKU,1H9Z,1H9G,8CKS,2XVV,2XVW,1P42,8I2G,1E7C,1E7G,2PLV,6NOK,6XV0,6PAU,6PAV,1WC9,7Z57,2BAU,2BAO,7C80,7C81,4DFX,1NN8,1DGI,7TBP,1COV,4DG0,4DG2,1EAH,1QA5,1CDK,4TKH,6I3V,6Q2X,8EY5,8AT5,1N5U,1BEV,6DY1,3FS1,5UR9,3EPD,3EPF,2I30,1TED,4DFZ,6HSC,1Z7S,1V26,4NTS,1UVA,1EV1,5IJD,1ASJ,3VQ2,7A9Y,7NXG,2BXO,7VC0,6NM1,5W7B,2GO3,1PIV,2JMG,7QFE,1L7Z,6L65,6HIK,6HIL,2R2I,1ICM,6LQ4,1CMK,1HK4,1HK5,1AYM,1AYN,6Y20,2XSI,6ZKM,6ZKL,6ZKO,6ZKN,6ZKI,6ZKH,6ZKK,6ZKJ,6ZKE,6ZKD,6ZKG,6ZKF,6ZKA,6ZKC,6ZKB,6ZKU,6ZKT,6ZKV,6ZKQ,6ZKP,6ZKS,6ZKR,4IQR,3J9F,1AR8,1AR9,1AR6,1AR7,5EZU,2I2Z,2NA0,4ZFZ,7QSN,6FYJ,5ZVT,6IWN,6IWH,1PZL,2L2E,6IWO,5L7K,7ZDP,2WEW,5HYB,3EPC,7YML,3B9L,3B9M,2E56,2NV3,4CU4,3J3O,5HTD,6NYU,2BXI,2BXK,2BXL,2BXM,2BXN,2BXP,2BXQ,6GK6,7R4G,7R4F,7R4D,7R4C,7R47,7R46,7R45,7R44,7R43,7R42,7R41,7R48,3A73,7OK6,8EW4,8EW7,6GE5,1VBB,1VBE,1VBD,5WOO,8A0U,8A0V,3PXP,5YHJ,2J65,6S6J,6S69,6S60,6S66,6S64,3L94,8A8R,7CB3,6YG9,2FO0,7M2M,6I8W,3IYL,6WUW,6U73,7TQT,1BJ5,7QSK,7QSM,7QSL,7QSO,2H3Q,2H3I,1LA3,7C9X,4G0S,7OWU,7OWO,3SQJ,7QW9,4AC8,7JWN,1POV,6ZCL,6ZCK,3SZ1,7TQS,7TQU,7ZD6,7ZDJ,7WJ3,7ZDM,7AAI,4RE0,5UC9,1CTP,2PWN,6BPP,6BPL,5TVI,5TV4,7ELL,7OV5,7OV6,7OV1,7OVR,6WA3,1TCO,1PVC,3TB8,1QJU,1QJX,1QJY,1ND2,2AF9,3J8F,7ZEB,1HA2,7BYD,4RDZ,6QRM,3UIV,1OOP,2KSQ,1PO2,1PO1,6B80,6Q36,2MV4,1NCR,2K4I,2K4H,5LMY,7EAK,6H6A,3JBG,3JBF,3JBC,5O9V,5O9U,5O9S,2GRX,2AGC,1FK2,7RK3,1QFF,1QFG,3USX,1JSA,6SK2,6SKJ,5T7C,3W9K,1D4M,4D65,3JBE,3JBD,3CX9,6EHJ,4G8A,4KU3,7OVQ,6Q0B,2L90,3UEV,4ZV5,2N1R,2K5U,1OPJ,1OPK,1OPL,3SRA,7ZDH,6IWG,6IWP,6XK0,3TDL,1NFP,1WC8,6GE3,6GE6,6GE4,6GEK,6GEI,6GEC,6GEG,6GEE,5IFO,6RWQ,6RWP,6RWR,5OAQ,8C17,7WOJ,7C9W,7C9V,7C9S,7C9Y,7C9Z,5GTP,5GTO,1HXS,5W78,5W7D,3MLM,2AG2,5LDL,5K06,7WUA,5LKF,5LKE,1O9X 11005 104036073 28875 CHEMBL111077 DB08231 2806 C06424 ZINC01530417 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182511 CC\C=C/C\C=C/C\C=C/C\C=C/CCOCC(O)=O InChI=1S/C17H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20-16-17(18)19/h3-4,6-7,9-10,12-13H,2,5,8,11,14-16H2,1H3,(H,18,19)/b4-3-,7-6-,10-9-,13-12- WBIVEHVMSFVPKF-LTKCOYKYSA-N 50242354 3-oxa-6,9,12,15-octadecatetraenoic acid::CHEMBL460445 Prostaglandin G/H synthase 2 Ovis aries >500000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242354&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44559941 104099041 CHEMBL460445 ZINC40862465 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50182512 CC\C=C/C\C=C/C\C=C/CC\C=C\COCC(O)=O InChI=1S/C17H26O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20-16-17(18)19/h3-4,6-7,9-10,13-14H,2,5,8,11-12,15-16H2,1H3,(H,18,19)/b4-3-,7-6-,10-9-,14-13+ BJYYIZGGYGZMCV-TWMAVKMASA-N 50242356 (5E,9Z,12Z,15Z)-3-oxaoctadeca-5,9,12,15-tetraenoic acid::CHEMBL460654 Prostaglandin G/H synthase 2 Ovis aries >500000 ChEMBL 10.1021/np000620d 10.7270/Q24J0DVJ 11421736 Ringbom, T; Huss, U; Stenholm, A; Flock, S; Skattebol, L; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242356&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44559943 104099043 CHEMBL460654 ZINC40865682 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50193452 CCCCc1ccc(NC=NO)c(C)c1 InChI=1S/C12H18N2O/c1-3-4-5-11-6-7-12(10(2)8-11)13-9-14-15/h6-9,15H,3-5H2,1-2H3,(H,13,14) LYNOGBKNFIHKLE-UHFFFAOYSA-N 50106737 CHEMBL267865::N-(4-Butyl-2-methyl-phenyl)-N'-hydroxy-formamidine::N-(4-butyl-2-methylphenyl)-N''-hydroxyimidoformamide::N-(4-butyl-2-methylphenyl)-N'-hydroxyimidoformamide Prostaglandin G/H synthase 2 Ovis aries 2300 ChEMBL 10.1016/s0960-894x(01)00614-x 10.7270/Q2RB73XW 11714595 Sato, M; Ishii, T; Kobayashi-Matsunaga, Y; Amada, H; Taniguchi, K; Miyata, N; Kameo, K Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106737&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search V16 6C94 2727594 104002202 CHEMBL267865 C02658 ZINC38337299 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236029 Cc1nn(-c2ccccc2)c2c1c(=O)oc1ccccc21 InChI=1S/C17H12N2O2/c1-11-15-16(19(18-11)12-7-3-2-4-8-12)13-9-5-6-10-14(13)21-17(15)20/h2-10H,1H3 XQVHTRBZHCYIDD-UHFFFAOYSA-N 50026583 CHEMBL412610 Prostaglandin G/H synthase 2 Ovis aries 2630 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026583&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2793709 313065283 CHEMBL412610 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236030 Cc1nn(-c2ccc(cc2)C(F)(F)F)c2c1c(=O)oc1ccccc21 InChI=1S/C18H11F3N2O2/c1-10-15-16(13-4-2-3-5-14(13)25-17(15)24)23(22-10)12-8-6-11(7-9-12)18(19,20)21/h2-9H,1H3 HJWQHUKFHOUQIY-UHFFFAOYSA-N 50026582 CHEMBL3331326 Prostaglandin G/H synthase 2 Ovis aries 1790 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026582&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91827649 313065282 CHEMBL3331326 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236031 Cc1nn(-c2ccc(Cl)cc2)c2c1c(=O)oc1ccccc21 InChI=1S/C17H11ClN2O2/c1-10-15-16(13-4-2-3-5-14(13)22-17(15)21)20(19-10)12-8-6-11(18)7-9-12/h2-9H,1H3 MDCDQTYITMCZET-UHFFFAOYSA-N 50026581 CHEMBL103836 Prostaglandin G/H synthase 2 Ovis aries 2430 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026581&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 13949095 313065281 CHEMBL103836 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236032 Cc1nn(-c2ccc(Br)cc2)c2c1c(=O)oc1ccccc21 InChI=1S/C17H11BrN2O2/c1-10-15-16(13-4-2-3-5-14(13)22-17(15)21)20(19-10)12-8-6-11(18)7-9-12/h2-9H,1H3 FAPYQKGKSVFQMX-UHFFFAOYSA-N 50026580 CHEMBL2402696 Prostaglandin G/H synthase 2 Ovis aries 3650 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026580&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71740484 313065280 CHEMBL2402696 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236033 Cc1nn(-c2ccc(F)cc2)c2c1c(=O)oc1ccccc21 InChI=1S/C17H11FN2O2/c1-10-15-16(13-4-2-3-5-14(13)22-17(15)21)20(19-10)12-8-6-11(18)7-9-12/h2-9H,1H3 PNYDGKZOMGYRJF-UHFFFAOYSA-N 50026579 CHEMBL3331330 Prostaglandin G/H synthase 2 Ovis aries 2360 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026579&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 102381531 313065279 CHEMBL3331330 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236034 COc1ccc2c3n(nc(C)c3c(=O)oc2c1)-c1ccc(cc1)C(F)(F)F InChI=1S/C19H13F3N2O3/c1-10-16-17(14-8-7-13(26-2)9-15(14)27-18(16)25)24(23-10)12-5-3-11(4-6-12)19(20,21)22/h3-9H,1-2H3 WVOOIWLLFXXQLM-UHFFFAOYSA-N 50026578 CHEMBL3331333 Prostaglandin G/H synthase 2 Ovis aries 4350 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026578&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118713636 313065278 CHEMBL3331333 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236035 Cc1nn(-c2ccc(cc2)C(F)(F)F)c2c1c(=O)oc1ccc(Cl)cc21 InChI=1S/C18H10ClF3N2O2/c1-9-15-16(13-8-11(19)4-7-14(13)26-17(15)25)24(23-9)12-5-2-10(3-6-12)18(20,21)22/h2-8H,1H3 OMKZSTYXXFFJTK-UHFFFAOYSA-N 50026577 CHEMBL3331339 Prostaglandin G/H synthase 2 Ovis aries 2580 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026577&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118713641 313065277 CHEMBL3331339 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50236036 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 150 ChEMBL 10.1016/j.bmcl.2014.08.050 10.7270/Q2J38V57 25219899 Grover, J; Kumar, V; Sobhia, ME; Jachak, SM National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235615 CC(C)Oc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C21H20O5S/c1-14(2)25-19-13-18(15-7-5-4-6-8-15)20(21(22)26-19)16-9-11-17(12-10-16)27(3,23)24/h4-14H,1-3H3 ZCPKXKQZCABKRQ-UHFFFAOYSA-N 50129497 6-Isopropoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL70106 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129497&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11153330 104021080 CHEMBL70106 ZINC13528593 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235617 Cc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C19H16O4S/c1-13-12-17(14-6-4-3-5-7-14)18(19(20)23-13)15-8-10-16(11-9-15)24(2,21)22/h3-12H,1-2H3 XHLMYDVGYNUWBV-UHFFFAOYSA-N 50129496 3-(4-Methanesulfonyl-phenyl)-6-methyl-4-phenyl-pyran-2-one::CHEMBL69197 Prostaglandin G/H synthase 2 Ovis aries 680.0 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129496&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11175192 104021079 CHEMBL69197 ZINC13528570 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235620 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 57 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235621 COc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C19H16O5S/c1-23-17-12-16(13-6-4-3-5-7-13)18(19(20)24-17)14-8-10-15(11-9-14)25(2,21)22/h3-12H,1-2H3 OIHJIUCRCIYZJQ-UHFFFAOYSA-N 50129501 3-(4-Methanesulfonyl-phenyl)-6-methoxy-4-phenyl-pyran-2-one::CHEMBL71329 Prostaglandin G/H synthase 2 Ovis aries 28300 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129501&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11187406 104021084 CHEMBL71329 ZINC13528584 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235622 CC(C)Sc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C21H20O4S2/c1-14(2)26-19-13-18(15-7-5-4-6-8-15)20(21(22)25-19)16-9-11-17(12-10-16)27(3,23)24/h4-14H,1-3H3 AHJYHOHEXCMRCC-UHFFFAOYSA-N 50129500 6-Isopropylsulfanyl-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL69853 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129500&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11384026 104021083 CHEMBL69853 ZINC13528625 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235625 CCc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C20H18O4S/c1-3-16-13-18(14-7-5-4-6-8-14)19(20(21)24-16)15-9-11-17(12-10-15)25(2,22)23/h4-13H,3H2,1-2H3 XYWPZLZWKITLIO-UHFFFAOYSA-N 50129502 6-Ethyl-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL71203 Prostaglandin G/H synthase 2 Ovis aries 1500 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129502&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11473693 104021085 CHEMBL71203 ZINC13528576 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235626 CSc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C19H16O4S2/c1-24-17-12-16(13-6-4-3-5-7-13)18(19(20)23-17)14-8-10-15(11-9-14)25(2,21)22/h3-12H,1-2H3 LBGUOUZNDJKAIJ-UHFFFAOYSA-N 50129498 3-(4-Methanesulfonyl-phenyl)-6-methylsulfanyl-4-phenyl-pyran-2-one::CHEMBL70835 Prostaglandin G/H synthase 2 Ovis aries 2800 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129498&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11406134 104021081 CHEMBL70835 ZINC13528616 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235627 CCOc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C20H18O5S/c1-3-24-18-13-17(14-7-5-4-6-8-14)19(20(21)25-18)15-9-11-16(12-10-15)26(2,22)23/h4-13H,3H2,1-2H3 CXFWNCNJNGMYQT-UHFFFAOYSA-N 50129503 6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL71200 Prostaglandin G/H synthase 2 Ovis aries 1300 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129503&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11462842 104021086 CHEMBL71200 ZINC13528590 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235628 CC(C)c1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C21H20O4S/c1-14(2)19-13-18(15-7-5-4-6-8-15)20(21(22)25-19)16-9-11-17(12-10-16)26(3,23)24/h4-14H,1-3H3 QPGGNWDUCHINFV-UHFFFAOYSA-N 50129499 6-Isopropyl-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL305282 Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129499&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11485473 104021082 CHEMBL305282 ZINC13528578 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235633 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 428 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50235634 CCSc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C20H18O4S2/c1-3-25-18-13-17(14-7-5-4-6-8-14)19(20(21)24-18)15-9-11-16(12-10-15)26(2,22)23/h4-13H,3H2,1-2H3 UKLQAJUWDDRARX-UHFFFAOYSA-N 50129504 6-Ethylsulfanyl-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL71833 Prostaglandin G/H synthase 2 Ovis aries 3.2 ChEMBL 10.1016/s0960-894x(03)00391-3 10.7270/Q2J102KC 12798335 Rao, PN; Amini, M; Li, H; Habeeb, AG; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129504&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10249568 104021087 CHEMBL71833 ZINC03814526 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257895 COc1ccc2[nH]cc(\C=C\C(=O)c3ccc(cc3)S(C)(=O)=O)c2c1 InChI=1S/C19H17NO4S/c1-24-15-6-9-18-17(11-15)14(12-20-18)5-10-19(21)13-3-7-16(8-4-13)25(2,22)23/h3-12,20H,1-2H3/b10-5+ YPZARZKURMCNSE-BJMVGYQFSA-N 50038394 CHEMBL3361119 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038394&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724705 313067243 CHEMBL3361119 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257899 COc1ccc2[nH]cc(\C=C\C(=O)c3ccc(cc3)C#N)c2c1 InChI=1S/C19H14N2O2/c1-23-16-7-8-18-17(10-16)15(12-21-18)6-9-19(22)14-4-2-13(11-20)3-5-14/h2-10,12,21H,1H3/b9-6+ NDJUZYLKLCDCEB-RMKNXTFCSA-N 50038395 CHEMBL3361120 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038395&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724706 313067244 CHEMBL3361120 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257900 CS(=O)(=O)c1ccc(cc1)C(=O)\C=C\c1c[nH]c2ccc(Cl)cc12 InChI=1S/C18H14ClNO3S/c1-24(22,23)15-6-2-12(3-7-15)18(21)9-4-13-11-20-17-8-5-14(19)10-16(13)17/h2-11,20H,1H3/b9-4+ DIZSZSJJYWHPCV-RUDMXATFSA-N 50038396 CHEMBL3361121 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038396&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724707 313067245 CHEMBL3361121 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257906 Clc1ccc2[nH]cc(\C=C\C(=O)c3ccc(cc3)C#N)c2c1 InChI=1S/C18H11ClN2O/c19-15-6-7-17-16(9-15)14(11-21-17)5-8-18(22)13-3-1-12(10-20)2-4-13/h1-9,11,21H/b8-5+ OYGZBBBNPDOKHM-VMPITWQZSA-N 50038397 CHEMBL3361122 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038397&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724708 313067246 CHEMBL3361122 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257907 CS(=O)(=O)c1ccc(cc1)C(=O)\C=C\c1c[nH]c2ccc(Br)cc12 InChI=1S/C18H14BrNO3S/c1-24(22,23)15-6-2-12(3-7-15)18(21)9-4-13-11-20-17-8-5-14(19)10-16(13)17/h2-11,20H,1H3/b9-4+ GXXSEYSJYRSXCQ-RUDMXATFSA-N 50038398 CHEMBL3361123 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038398&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724709 313067247 CHEMBL3361123 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257909 Brc1ccc2[nH]cc(\C=C\C(=O)c3ccc(cc3)C#N)c2c1 InChI=1S/C18H11BrN2O/c19-15-6-7-17-16(9-15)14(11-21-17)5-8-18(22)13-3-1-12(10-20)2-4-13/h1-9,11,21H/b8-5+ QYEFQRPRWKTQGT-VMPITWQZSA-N 50038399 CHEMBL3361124 Prostaglandin G/H synthase 2 Ovis aries 9.5 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038399&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724710 313067248 CHEMBL3361124 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257912 Cn1cc(\C=C\C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc12 InChI=1S/C19H17NO3S/c1-20-13-15(17-5-3-4-6-18(17)20)9-12-19(21)14-7-10-16(11-8-14)24(2,22)23/h3-13H,1-2H3/b12-9+ YXZTVKMYVWFNDL-FMIVXFBMSA-N 50038400 CHEMBL3361125 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038400&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724711 313067249 CHEMBL3361125 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257913 Cn1cc(\C=C\C(=O)c2ccc(cc2)C#N)c2ccccc12 InChI=1S/C19H14N2O/c1-21-13-16(17-4-2-3-5-18(17)21)10-11-19(22)15-8-6-14(12-20)7-9-15/h2-11,13H,1H3/b11-10+ PRPPJYASQDZTHF-ZHACJKMWSA-N 50038401 CHEMBL3361126 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038401&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724712 313067250 CHEMBL3361126 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257915 CC(=O)Nc1ccc(cc1)C(=O)\C=C\c1cn(C)c2ccccc12 InChI=1S/C20H18N2O2/c1-14(23)21-17-10-7-15(8-11-17)20(24)12-9-16-13-22(2)19-6-4-3-5-18(16)19/h3-13H,1-2H3,(H,21,23)/b12-9+ JFLVDQNITYMTSC-FMIVXFBMSA-N 50038421 CHEMBL3361127 Prostaglandin G/H synthase 2 Ovis aries >10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038421&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118724713 313067251 CHEMBL3361127 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50257916 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 10.0 ChEMBL 10.1016/j.ejmech.2014.10.056 10.7270/Q2PG1TBF 25462246 Özdemir, A; Altintop, MD; Turan-Zitouni, G; Çiftçi, GA; Ertorun, I; Alatas, Ö; Kaplancikli, ZA Anadolu University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252894 NC(=S)N\N=C/c1cn(nc1-c1ccc(Br)cc1)-c1ccccc1 InChI=1S/C17H14BrN5S/c18-14-8-6-12(7-9-14)16-13(10-20-21-17(19)24)11-23(22-16)15-4-2-1-3-5-15/h1-11H,(H3,19,21,24)/b20-10- YEPRCXGNJDVZIP-JMIUGGIZSA-N 50035971 CHEMBL3338718 Prostaglandin G/H synthase 2 Ovis aries 6330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035971&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5532506 103943838 CHEMBL3338718 ZINC13740054 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252896 NC(=S)N\N=C/c1cn(nc1-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C17H14ClN5S/c18-14-8-6-12(7-9-14)16-13(10-20-21-17(19)24)11-23(22-16)15-4-2-1-3-5-15/h1-11H,(H3,19,21,24)/b20-10- RXJSJSZRZCCGNA-JMIUGGIZSA-N 50035979 CHEMBL3338717 Prostaglandin G/H synthase 2 Ovis aries 3330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035979&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5457247 312528633 CHEMBL3338717 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252897 Clc1ccc(cc1)-c1nn(cc1\C=N/NC(=S)Nc1ccccc1)-c1ccccc1 InChI=1S/C23H18ClN5S/c24-19-13-11-17(12-14-19)22-18(16-29(28-22)21-9-5-2-6-10-21)15-25-27-23(30)26-20-7-3-1-4-8-20/h1-16H,(H2,26,27,30)/b25-15- SOTHXVMXJQFBQJ-MYYYXRDXSA-N 50035942 CHEMBL3338720 Prostaglandin G/H synthase 2 Ovis aries 8330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035942&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715493 103943809 CHEMBL3338720 ZINC26646594 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252898 COc1ccc(cc1)-c1nn(cc1\C=N/NC(N)=S)-c1ccccc1 InChI=1S/C18H17N5OS/c1-24-16-9-7-13(8-10-16)17-14(11-20-21-18(19)25)12-23(22-17)15-5-3-2-4-6-15/h2-12H,1H3,(H3,19,21,25)/b20-11- CNWNCQAAPOYYNZ-JAIQZWGSSA-N 50035950 CHEMBL3338719 Prostaglandin G/H synthase 2 Ovis aries 2500 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035950&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 102282946 103943817 CHEMBL3338719 ZINC13516111 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252900 CC(=O)N(C1=NN(C(S1)c1cn(nc1-c1ccc(Br)cc1)-c1ccccc1)C(C)=O)c1ccccc1 InChI=1S/C27H22BrN5O2S/c1-18(34)32(23-11-7-4-8-12-23)27-30-33(19(2)35)26(36-27)24-17-31(22-9-5-3-6-10-22)29-25(24)20-13-15-21(28)16-14-20/h3-17,26H,1-2H3 PAYBXDFCBFUINN-UHFFFAOYSA-N 50035939 CHEMBL3338733 Prostaglandin G/H synthase 2 Ovis aries 6500 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035939&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715506 103943806 CHEMBL3338733 ZINC26649280 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252902 CC(=O)N(C1=NN(C(S1)c1cn(nc1-c1ccc(Cl)cc1)-c1ccccc1)C(C)=O)c1ccccc1 InChI=1S/C27H22ClN5O2S/c1-18(34)32(23-11-7-4-8-12-23)27-30-33(19(2)35)26(36-27)24-17-31(22-9-5-3-6-10-22)29-25(24)20-13-15-21(28)16-14-20/h3-17,26H,1-2H3 WNEKMGMNGQIUNB-UHFFFAOYSA-N 50035941 CHEMBL3338732 Prostaglandin G/H synthase 2 Ovis aries 3330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035941&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715505 103943808 CHEMBL3338732 ZINC26649954 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252905 COc1ccc(cc1)-c1nn(cc1C1SC(=NN1C(C)=O)N(C(C)=O)c1ccccc1)-c1ccccc1 InChI=1S/C28H25N5O3S/c1-19(34)32(23-12-8-5-9-13-23)28-30-33(20(2)35)27(37-28)25-18-31(22-10-6-4-7-11-22)29-26(25)21-14-16-24(36-3)17-15-21/h4-18,27H,1-3H3 TVAYTPOBVFPTPZ-UHFFFAOYSA-N 50035937 CHEMBL3338734 Prostaglandin G/H synthase 2 Ovis aries 3330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035937&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715507 103943804 CHEMBL3338734 ZINC26648596 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252909 Brc1ccc(cc1)-c1nn(cc1\C=N/N=C1/SCC(=O)N1c1ccccc1)-c1ccccc1 InChI=1S/C25H18BrN5OS/c26-20-13-11-18(12-14-20)24-19(16-30(29-24)21-7-3-1-4-8-21)15-27-28-25-31(23(32)17-33-25)22-9-5-2-6-10-22/h1-16H,17H2/b27-15-,28-25+ BLADVKVHODIXOE-JFHWQFGQSA-N 50035934 CHEMBL3338727 Prostaglandin G/H synthase 2 Ovis aries 17500 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035934&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715500 103943801 CHEMBL3338727 ZINC26648958 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252911 CC(=O)NC1=NN(C(S1)c1cn(nc1-c1ccc(Cl)cc1)-c1ccccc1)C(C)=O InChI=1S/C21H18ClN5O2S/c1-13(28)23-21-25-27(14(2)29)20(30-21)18-12-26(17-6-4-3-5-7-17)24-19(18)15-8-10-16(22)11-9-15/h3-12,20H,1-2H3,(H,23,25,28) CYYWJQYFDAJKLO-UHFFFAOYSA-N 50035975 CHEMBL3338729 Prostaglandin G/H synthase 2 Ovis aries 2330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035975&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715502 312528632 CHEMBL3338729 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252913 COc1ccc(cc1)-c1nn(cc1\C=N/N=C1/SCC(=O)N1c1ccccc1)-c1ccccc1 InChI=1S/C26H21N5O2S/c1-33-23-14-12-19(13-15-23)25-20(17-30(29-25)21-8-4-2-5-9-21)16-27-28-26-31(24(32)18-34-26)22-10-6-3-7-11-22/h2-17H,18H2,1H3/b27-16-,28-26+ PEFXOJDIIDCTNT-CYJDQBSTSA-N 50035988 CHEMBL3338728 Prostaglandin G/H synthase 2 Ovis aries 12660 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035988&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715501 103943853 CHEMBL3338728 ZINC27874579 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252915 COc1ccc(cc1)-c1nn(cc1C1SC(NC(C)=O)=NN1C(C)=O)-c1ccccc1 InChI=1S/C22H21N5O3S/c1-14(28)23-22-25-27(15(2)29)21(31-22)19-13-26(17-7-5-4-6-8-17)24-20(19)16-9-11-18(30-3)12-10-16/h4-13,21H,1-3H3,(H,23,25,28) ODRWLHLGKCRXIZ-UHFFFAOYSA-N 50035943 CHEMBL3338731 Prostaglandin G/H synthase 2 Ovis aries 1330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035943&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715504 103943810 CHEMBL3338731 ZINC26646557 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252916 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 3100 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252918 CC(=O)NC1=NN(C(S1)c1cn(nc1-c1ccc(Br)cc1)-c1ccccc1)C(C)=O InChI=1S/C21H18BrN5O2S/c1-13(28)23-21-25-27(14(2)29)20(30-21)18-12-26(17-6-4-3-5-7-17)24-19(18)15-8-10-16(22)11-9-15/h3-12,20H,1-2H3,(H,23,25,28) XRMMYYXAYFELFR-UHFFFAOYSA-N 50035966 CHEMBL3338730 Prostaglandin G/H synthase 2 Ovis aries 2500 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035966&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715503 103943833 CHEMBL3338730 ZINC13740068 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252920 COc1ccc(cc1)-c1nn(cc1\C=N/NC(=S)Nc1ccccc1)-c1ccccc1 InChI=1S/C24H21N5OS/c1-30-22-14-12-18(13-15-22)23-19(17-29(28-23)21-10-6-3-7-11-21)16-25-27-24(31)26-20-8-4-2-5-9-20/h2-17H,1H3,(H2,26,27,31)/b25-16- ZMRFZLPILDJSEV-XYGWBWBKSA-N 50035938 CHEMBL3338722 Prostaglandin G/H synthase 2 Ovis aries 7330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035938&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715495 103943805 CHEMBL3338722 ZINC26647712 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252923 Brc1ccc(cc1)-c1nn(cc1\C=N/NC(=S)Nc1ccccc1)-c1ccccc1 InChI=1S/C23H18BrN5S/c24-19-13-11-17(12-14-19)22-18(16-29(28-22)21-9-5-2-6-10-21)15-25-27-23(30)26-20-7-3-1-4-8-20/h1-16H,(H2,26,27,30)/b25-15- HJTGLOARSHOTKT-MYYYXRDXSA-N 50035940 CHEMBL3338721 Prostaglandin G/H synthase 2 Ovis aries 11660 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035940&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715494 103943807 CHEMBL3338721 ZINC26642859 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252924 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252926 Brc1ccc(cc1)-c1nn(cc1\C=N/NC1=NC(=O)CS1)-c1ccccc1 InChI=1S/C19H14BrN5OS/c20-15-8-6-13(7-9-15)18-14(10-21-23-19-22-17(26)12-27-19)11-25(24-18)16-4-2-1-3-5-16/h1-11H,12H2,(H,22,23,26)/b21-10- WFPMYCBPVMDNJN-FBHDLOMBSA-N 50035935 CHEMBL3338724 Prostaglandin G/H synthase 2 Ovis aries 12660 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035935&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715497 103943802 CHEMBL3338724 ZINC26580166 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252928 Clc1ccc(cc1)-c1nn(cc1\C=N/NC1=NC(=O)CS1)-c1ccccc1 InChI=1S/C19H14ClN5OS/c20-15-8-6-13(7-9-15)18-14(10-21-23-19-22-17(26)12-27-19)11-25(24-18)16-4-2-1-3-5-16/h1-11H,12H2,(H,22,23,26)/b21-10- PXOYCHIZWKBTTH-FBHDLOMBSA-N 50035936 CHEMBL3338723 Prostaglandin G/H synthase 2 Ovis aries 10660 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035936&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715496 103943803 CHEMBL3338723 ZINC26642231 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252929 Clc1ccc(cc1)-c1nn(cc1\C=N/N=C1/SCC(=O)N1c1ccccc1)-c1ccccc1 InChI=1S/C25H18ClN5OS/c26-20-13-11-18(12-14-20)24-19(16-30(29-24)21-7-3-1-4-8-21)15-27-28-25-31(23(32)17-33-25)22-9-5-2-6-10-22/h1-16H,17H2/b27-15-,28-25+ HXBWLGGORIFEFU-JFHWQFGQSA-N 50035990 CHEMBL3338726 Prostaglandin G/H synthase 2 Ovis aries 15330 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035990&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715499 103943855 CHEMBL3338726 ZINC27874586 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50252930 COc1ccc(cc1)-c1nn(cc1\C=N/NC1=NC(=O)CS1)-c1ccccc1 InChI=1S/C20H17N5O2S/c1-27-17-9-7-14(8-10-17)19-15(11-21-23-20-22-18(26)13-28-20)12-25(24-19)16-5-3-2-4-6-16/h2-12H,13H2,1H3,(H,22,23,26)/b21-11- JUCBMIDXALUABN-NHDPSOOVSA-N 50035992 CHEMBL3338725 Prostaglandin G/H synthase 2 Ovis aries 8500 ChEMBL 10.1016/j.bmcl.2014.08.062 10.7270/Q2X92CXH 25444084 Alegaon, SG; Hirpara, MB; Alagawadi, KR; Hullatti, KK; Kashniyal, K KLE University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035992&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118715498 103943857 CHEMBL3338725 ZINC27880147 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50265794 NNC(=O)Cn1c(nc2ccccc12)-c1ccc(CNc2ccncc2)o1 InChI=1S/C19H18N6O2/c20-24-18(26)12-25-16-4-2-1-3-15(16)23-19(25)17-6-5-14(27-17)11-22-13-7-9-21-10-8-13/h1-10H,11-12,20H2,(H,21,22)(H,24,26) GRGQKPUSPPAJKE-UHFFFAOYSA-N 50044257 CHEMBL3337483 Prostaglandin G/H synthase 2 Ovis aries 470 ChEMBL 10.1016/j.ejmech.2014.01.063 10.7270/Q2BK1F0B 24576797 Temirak, A; Shaker, YM; Ragab, FA; Ali, MM; Ali, HI; El Diwani, HI National Research Centre, Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044257&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118714722 313068152 CHEMBL3337483 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50265795 Nn1c(Cn2c(nc3ccccc23)-c2ccco2)n[nH]c1=S InChI=1S/C14H12N6OS/c15-20-12(17-18-14(20)22)8-19-10-5-2-1-4-9(10)16-13(19)11-6-3-7-21-11/h1-7H,8,15H2,(H,18,22) IFYGHFFHFVSPSP-UHFFFAOYSA-N 50044258 CHEMBL3337489 Prostaglandin G/H synthase 2 Ovis aries 360 ChEMBL 10.1016/j.ejmech.2014.01.063 10.7270/Q2BK1F0B 24576797 Temirak, A; Shaker, YM; Ragab, FA; Ali, MM; Ali, HI; El Diwani, HI National Research Centre, Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044258&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118714728 313068153 CHEMBL3337489 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50265796 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 280 ChEMBL 10.1016/j.ejmech.2014.01.063 10.7270/Q2BK1F0B 24576797 Temirak, A; Shaker, YM; Ragab, FA; Ali, MM; Ali, HI; El Diwani, HI National Research Centre, Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276546 CS(=O)(=O)c1ccc(cc1)-c1c(cc(oc1=O)-c1ccc(cc1)[N+]([O-])=O)-c1ccccc1 InChI=1S/C24H17NO6S/c1-32(29,30)20-13-9-18(10-14-20)23-21(16-5-3-2-4-6-16)15-22(31-24(23)26)17-7-11-19(12-8-17)25(27)28/h2-15H,1H3 XJZDQMGPHSDCSY-UHFFFAOYSA-N 50150718 3-(4-Methanesulfonyl-phenyl)-6-(4-nitro-phenyl)-4-phenyl-pyran-2-one::CHEMBL434350 Prostaglandin G/H synthase 2 Ovis aries 7000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150718&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11190068 104039077 CHEMBL434350 ZINC13581320 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276547 CS(=O)(=O)c1ccc(cc1)-c1c(cc(oc1=O)-c1ccccc1)-c1ccccc1 InChI=1S/C24H18O4S/c1-29(26,27)20-14-12-19(13-15-20)23-21(17-8-4-2-5-9-17)16-22(28-24(23)25)18-10-6-3-7-11-18/h2-16H,1H3 SNYOIDHVUOVRHA-UHFFFAOYSA-N 50150719 3-(4-Methanesulfonyl-phenyl)-4,6-diphenyl-pyran-2-one::CHEMBL188262 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150719&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11475133 104039078 CHEMBL188262 ZINC13581284 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276550 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70.0 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276552 CS(=O)(=O)c1ccc(cc1)-c1c(cc(oc1=O)-c1ccc(N)cc1)-c1ccccc1 InChI=1S/C24H19NO4S/c1-30(27,28)20-13-9-18(10-14-20)23-21(16-5-3-2-4-6-16)15-22(29-24(23)26)17-7-11-19(25)12-8-17/h2-15H,25H2,1H3 SMSIQUPBSSSMRC-UHFFFAOYSA-N 50150723 6-(4-Amino-phenyl)-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL184566 Prostaglandin G/H synthase 2 Ovis aries 800 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150723&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11384526 104039082 CHEMBL184566 ZINC13581322 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276553 CSc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccccc2)c(=O)o1 InChI=1S/C25H20O4S2/c1-30-20-12-8-18(9-13-20)23-16-22(17-10-14-21(15-11-17)31(2,27)28)24(25(26)29-23)19-6-4-3-5-7-19/h3-16H,1-2H3 VDKZQYMMGKZJAC-UHFFFAOYSA-N 50150724 4-(4-Methanesulfonyl-phenyl)-6-(4-methylsulfanyl-phenyl)-3-phenyl-pyran-2-one::CHEMBL186351 Prostaglandin G/H synthase 2 Ovis aries 4500 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150724&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11190106 104039083 CHEMBL186351 ZINC13581326 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276558 COc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C25H20O5S/c1-29-20-12-8-18(9-13-20)23-16-22(17-6-4-3-5-7-17)24(25(26)30-23)19-10-14-21(15-11-19)31(2,27)28/h3-16H,1-2H3 AVUUCASFFDRBJI-UHFFFAOYSA-N 50150726 3-(4-Methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-4-phenyl-pyran-2-one::6-(4-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl)-4-phenyl-2H-pyran-2-one::CHEMBL187137 Prostaglandin G/H synthase 2 Ovis aries 20 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150726&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10071460 104039085 CHEMBL187137 ZINC03963001 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276559 CS(=O)(=O)c1ccc(cc1)-c1c(cc(oc1=O)-c1ccc(O)cc1)-c1ccccc1 InChI=1S/C24H18O5S/c1-30(27,28)20-13-9-18(10-14-20)23-21(16-5-3-2-4-6-16)15-22(29-24(23)26)17-7-11-19(25)12-8-17/h2-15,25H,1H3 VIVAKNAVLHNDRM-UHFFFAOYSA-N 50150725 6-(4-Hydroxy-phenyl)-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL363547 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150725&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11154312 104039084 CHEMBL363547 ZINC13581324 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276563 COc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccc(F)cc2)c(=O)o1 InChI=1S/C25H19FO5S/c1-30-20-11-5-17(6-12-20)23-15-22(16-7-13-21(14-8-16)32(2,28)29)24(25(27)31-23)18-3-9-19(26)10-4-18/h3-15H,1-2H3 PRKFAYYSPVLICT-UHFFFAOYSA-N 50150729 3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-pyran-2-one::CHEMBL187177 Prostaglandin G/H synthase 2 Ovis aries 1300 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150729&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11178448 104039088 CHEMBL187177 ZINC13581312 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276564 CCOc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccc(F)cc2)c(=O)o1 InChI=1S/C26H21FO5S/c1-3-31-21-12-6-18(7-13-21)24-16-23(17-8-14-22(15-9-17)33(2,29)30)25(26(28)32-24)19-4-10-20(27)11-5-19/h4-16H,3H2,1-2H3 UBVMIZBRIVTXCS-UHFFFAOYSA-N 50150731 6-(4-Ethoxy-phenyl)-3-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-pyran-2-one::CHEMBL188354 Prostaglandin G/H synthase 2 Ovis aries 14500 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150731&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11431208 104039090 CHEMBL188354 ZINC13581314 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276566 COc1ccc(cc1)-c1cc(-c2ccc(F)cc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C25H19FO5S/c1-30-20-11-5-17(6-12-20)23-15-22(16-3-9-19(26)10-4-16)24(25(27)31-23)18-7-13-21(14-8-18)32(2,28)29/h3-15H,1-2H3 TZZDJFFFVCVOMH-UHFFFAOYSA-N 50150733 4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-pyran-2-one::CHEMBL446888 Prostaglandin G/H synthase 2 Ovis aries 1160 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150733&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11305485 104039092 CHEMBL446888 ZINC13581293 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276568 COc1ccc(cc1)-c1cc(-c2cccnc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C24H19NO5S/c1-29-19-9-5-16(6-10-19)22-14-21(18-4-3-13-25-15-18)23(24(26)30-22)17-7-11-20(12-8-17)31(2,27)28/h3-15H,1-2H3 GSQPAWWGCMVJAH-UHFFFAOYSA-N 50150735 3-(4-Methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-4-pyridin-3-yl-pyran-2-one::CHEMBL184737 Prostaglandin G/H synthase 2 Ovis aries 30 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150735&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11441881 104039094 CHEMBL184737 ZINC13581328 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276570 CS(=O)(=O)c1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccccc2)c(=O)o1 InChI=1S/C24H18O4S/c1-29(26,27)20-14-12-18(13-15-20)22-16-21(17-8-4-2-5-9-17)23(24(25)28-22)19-10-6-3-7-11-19/h2-16H,1H3 ZPJDGHCZBKIRFX-UHFFFAOYSA-N 50150737 6-(4-Methanesulfonyl-phenyl)-3,4-diphenyl-pyran-2-one::CHEMBL187529 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150737&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11304193 104039096 CHEMBL187529 ZINC13581297 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276572 CCOc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccccc2)c(=O)o1 InChI=1S/C26H22O5S/c1-3-30-21-13-9-19(10-14-21)24-17-23(18-11-15-22(16-12-18)32(2,28)29)25(26(27)31-24)20-7-5-4-6-8-20/h4-17H,3H2,1-2H3 XPNPOVQRZAWSCD-UHFFFAOYSA-N 50150741 6-(4-Ethoxy-phenyl)-4-(4-methanesulfonyl-phenyl)-3-phenyl-pyran-2-one::CHEMBL189387 Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150741&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11259380 104039100 CHEMBL189387 ZINC13581308 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276574 CS(=O)(=O)c1ccc(cc1)-c1cc(oc(=O)c1-c1cccnc1)-c1ccccc1 InChI=1S/C23H17NO4S/c1-29(26,27)19-11-9-16(10-12-19)20-14-21(17-6-3-2-4-7-17)28-23(25)22(20)18-8-5-13-24-15-18/h2-15H,1H3 UARYGEVXUVTIKB-UHFFFAOYSA-N 50150739 4-(4-Methanesulfonyl-phenyl)-6-phenyl-3-pyridin-3-yl-pyran-2-one::CHEMBL363971 Prostaglandin G/H synthase 2 Ovis aries 330 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150739&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11235066 104039098 CHEMBL363971 ZINC13581330 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276575 CCOc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)N=[N+]=[N-])c(=O)o1 InChI=1S/C25H19N3O3/c1-2-30-21-14-10-18(11-15-21)23-16-22(17-6-4-3-5-7-17)24(25(29)31-23)19-8-12-20(13-9-19)27-28-26/h3-16H,2H2,1H3 WYBPCMDGHZAMDV-UHFFFAOYSA-N 50150740 3-(4-Azido-phenyl)-6-(4-ethoxy-phenyl)-4-phenyl-pyran-2-one::CHEMBL189546 Prostaglandin G/H synthase 2 Ovis aries 2300 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150740&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11475351 104039099 CHEMBL189546 ZINC13581340 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276576 COc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)N=[N+]=[N-])c(=O)o1 InChI=1S/C24H17N3O3/c1-29-20-13-9-17(10-14-20)22-15-21(16-5-3-2-4-6-16)23(24(28)30-22)18-7-11-19(12-8-18)26-27-25/h2-15H,1H3 HADLCHPZNIUBQY-UHFFFAOYSA-N 50150738 3-(4-Azido-phenyl)-6-(4-methoxy-phenyl)-4-phenyl-pyran-2-one::CHEMBL363052 Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150738&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11406785 104039097 CHEMBL363052 ZINC13581338 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276577 CSc1ccc(cc1)-c1cc(-c2ccc(F)cc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C25H19FO4S2/c1-31-20-11-5-17(6-12-20)23-15-22(16-3-9-19(26)10-4-16)24(25(27)30-23)18-7-13-21(14-8-18)32(2,28)29/h3-15H,1-2H3 DCYGPUNFYABRST-UHFFFAOYSA-N 50150720 4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6-(4-methylsulfanyl-phenyl)-pyran-2-one::CHEMBL188933 Prostaglandin G/H synthase 2 Ovis aries 31600 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150720&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11442695 104039079 CHEMBL188933 ZINC13581318 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276579 CSc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)N=[N+]=[N-])c(=O)o1 InChI=1S/C24H17N3O2S/c1-30-20-13-9-17(10-14-20)22-15-21(16-5-3-2-4-6-16)23(24(28)29-22)18-7-11-19(12-8-18)26-27-25/h2-15H,1H3 ZDIDWNMWMFIASD-UHFFFAOYSA-N 50150722 3-(4-Azido-phenyl)-6-(4-methylsulfanyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL185820 Prostaglandin G/H synthase 2 Ovis aries 380 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150722&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11429814 104039081 CHEMBL185820 ZINC13581342 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276580 CSc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C25H20O4S2/c1-30-20-12-8-18(9-13-20)23-16-22(17-6-4-3-5-7-17)24(25(26)29-23)19-10-14-21(15-11-19)31(2,27)28/h3-16H,1-2H3 AJZNJPCIZIZPPQ-UHFFFAOYSA-N 50150742 3-(4-Methanesulfonyl-phenyl)-6-(4-methylsulfanyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL365699 Prostaglandin G/H synthase 2 Ovis aries 160 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150742&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11476420 104039101 CHEMBL365699 ZINC13581316 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276582 CCOc1ccc(cc1)-c1cc(-c2ccc(F)cc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C26H21FO5S/c1-3-31-21-12-6-18(7-13-21)24-16-23(17-4-10-20(27)11-5-17)25(26(28)32-24)19-8-14-22(15-9-19)33(2,29)30/h4-16H,3H2,1-2H3 ILQQWUVXIGNZFG-UHFFFAOYSA-N 50150745 6-(4-Ethoxy-phenyl)-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyran-2-one::CHEMBL425712 Prostaglandin G/H synthase 2 Ovis aries 158000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150745&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11155507 104039104 CHEMBL425712 ZINC13581295 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276583 CS(=O)(=O)c1ccc(cc1)-c1cc(oc(=O)c1-c1ccccc1)-c1ccc(cc1)C(F)(F)F InChI=1S/C25H17F3O4S/c1-33(30,31)20-13-9-16(10-14-20)21-15-22(17-7-11-19(12-8-17)25(26,27)28)32-24(29)23(21)18-5-3-2-4-6-18/h2-15H,1H3 FYOIVGQPIZYFBS-UHFFFAOYSA-N 50150743 4-(4-Methanesulfonyl-phenyl)-3-phenyl-6-(4-trifluoromethyl-phenyl)-pyran-2-one::CHEMBL184941 Prostaglandin G/H synthase 2 Ovis aries 3200 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150743&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11225183 104039102 CHEMBL184941 ZINC13581304 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276585 Cc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C25H20O4S/c1-17-8-10-19(11-9-17)23-16-22(18-6-4-3-5-7-18)24(25(26)29-23)20-12-14-21(15-13-20)30(2,27)28/h3-16H,1-2H3 KIVVXWMWIFIXDF-UHFFFAOYSA-N 50150744 3-(4-Methanesulfonyl-phenyl)-4-phenyl-6-p-tolyl-pyran-2-one::CHEMBL363769 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150744&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11292953 104039103 CHEMBL363769 ZINC13581286 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276586 CS(=O)(=O)c1ccc(cc1)-c1cc(oc(=O)c1-c1ccncc1)-c1ccccc1 InChI=1S/C23H17NO4S/c1-29(26,27)19-9-7-16(8-10-19)20-15-21(17-5-3-2-4-6-17)28-23(25)22(20)18-11-13-24-14-12-18/h2-15H,1H3 GUMHESOLEAJFOD-UHFFFAOYSA-N 50150746 4-(4-Methanesulfonyl-phenyl)-6-phenyl-3-pyridin-4-yl-pyran-2-one::CHEMBL365274 Prostaglandin G/H synthase 2 Ovis aries 3000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150746&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11395560 104039105 CHEMBL365274 ZINC13581334 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276587 COc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccncc2)c(=O)o1 InChI=1S/C24H19NO5S/c1-29-19-7-3-17(4-8-19)22-15-21(16-5-9-20(10-6-16)31(2,27)28)23(24(26)30-22)18-11-13-25-14-12-18/h3-15H,1-2H3 NVDLDWBUCGDCRR-UHFFFAOYSA-N 50150748 4-(4-Methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-3-pyridin-4-yl-pyran-2-one::CHEMBL186821 Prostaglandin G/H synthase 2 Ovis aries 320 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150748&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11476001 104039107 CHEMBL186821 ZINC13581336 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276588 CCOc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C26H22O5S/c1-3-30-21-13-9-19(10-14-21)24-17-23(18-7-5-4-6-8-18)25(26(27)31-24)20-11-15-22(16-12-20)32(2,28)29/h4-17H,3H2,1-2H3 UPZNCVBAWLLXRV-UHFFFAOYSA-N 50150734 6-(4-Ethoxy-phenyl)-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL184767 Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150734&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11213001 104039093 CHEMBL184767 ZINC03963000 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276589 CS(=O)(=O)c1ccc(cc1)-c1cc(oc(=O)c1-c1ccccc1)-c1ccccc1 InChI=1S/C24H18O4S/c1-29(26,27)20-14-12-17(13-15-20)21-16-22(18-8-4-2-5-9-18)28-24(25)23(21)19-10-6-3-7-11-19/h2-16H,1H3 UECQDYSDNRXIAQ-UHFFFAOYSA-N 50150727 4-(4-Methanesulfonyl-phenyl)-3,6-diphenyl-pyran-2-one::CHEMBL187583 Prostaglandin G/H synthase 2 Ovis aries 1300 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150727&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11292569 104039086 CHEMBL187583 ZINC13581298 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276591 CS(=O)(=O)c1ccc(cc1)-c1c(cc(oc1=O)-c1ccc(cc1)C(F)(F)F)-c1ccccc1 InChI=1S/C25H17F3O4S/c1-33(30,31)20-13-9-18(10-14-20)23-21(16-5-3-2-4-6-16)15-22(32-24(23)29)17-7-11-19(12-8-17)25(26,27)28/h2-15H,1H3 CVCBPGCZOPVFKB-UHFFFAOYSA-N 50150732 3-(4-Methanesulfonyl-phenyl)-4-phenyl-6-(4-trifluoromethyl-phenyl)-pyran-2-one::CHEMBL184025 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150732&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11202223 104039091 CHEMBL184025 ZINC13581289 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276594 Cc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccccc2)c(=O)o1 InChI=1S/C25H20O4S/c1-17-8-10-19(11-9-17)23-16-22(18-12-14-21(15-13-18)30(2,27)28)24(25(26)29-23)20-6-4-3-5-7-20/h3-16H,1-2H3 LRANBAYKACDWTK-UHFFFAOYSA-N 50150749 4-(4-Methanesulfonyl-phenyl)-3-phenyl-6-p-tolyl-pyran-2-one::CHEMBL365662 Prostaglandin G/H synthase 2 Ovis aries 1200 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150749&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11223781 104039108 CHEMBL365662 ZINC13581300 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276596 CCc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccccc2)c(=O)o1 InChI=1S/C26H22O4S/c1-3-18-9-11-20(12-10-18)24-17-23(19-13-15-22(16-14-19)31(2,28)29)25(26(27)30-24)21-7-5-4-6-8-21/h4-17H,3H2,1-2H3 TUCFIJMNDRFCCX-UHFFFAOYSA-N 50150730 6-(4-Ethyl-phenyl)-4-(4-methanesulfonyl-phenyl)-3-phenyl-pyran-2-one::CHEMBL365624 Prostaglandin G/H synthase 2 Ovis aries 1400 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150730&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11327882 104039089 CHEMBL365624 ZINC13581302 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276598 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276603 CS(=O)(=O)c1ccc(cc1)-c1c(cc(oc1=O)-c1ccc(F)cc1)-c1ccccc1 InChI=1S/C24H17FO4S/c1-30(27,28)20-13-9-18(10-14-20)23-21(16-5-3-2-4-6-16)15-22(29-24(23)26)17-7-11-19(25)12-8-17/h2-15H,1H3 HAQQYFIHRGNQLJ-UHFFFAOYSA-N 50150736 6-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL186359 Prostaglandin G/H synthase 2 Ovis aries 5100 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150736&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11396038 104039095 CHEMBL186359 ZINC13581291 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276604 CS(=O)(=O)c1ccc(cc1)-c1c(cc(oc1=O)-c1ccccc1)-c1cccnc1 InChI=1S/C23H17NO4S/c1-29(26,27)19-11-9-17(10-12-19)22-20(18-8-5-13-24-15-18)14-21(28-23(22)25)16-6-3-2-4-7-16/h2-15H,1H3 KBTNUIBNCVVZKJ-UHFFFAOYSA-N 50150721 3-(4-Methanesulfonyl-phenyl)-6-phenyl-4-pyridin-3-yl-pyran-2-one::CHEMBL360200 Prostaglandin G/H synthase 2 Ovis aries 8000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150721&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11475166 104039080 CHEMBL360200 ZINC12352439 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276605 CCc1ccc(cc1)-c1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C26H22O4S/c1-3-18-9-11-20(12-10-18)24-17-23(19-7-5-4-6-8-19)25(26(27)30-24)21-13-15-22(16-14-21)31(2,28)29/h4-17H,3H2,1-2H3 CSONLWUEBYUUKB-UHFFFAOYSA-N 50150747 6-(4-Ethyl-phenyl)-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL440382 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150747&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11396299 104039106 CHEMBL440382 ZINC13581288 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276607 COc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2ccccc2)c(=O)o1 InChI=1S/C25H20O5S/c1-29-20-12-8-18(9-13-20)23-16-22(17-10-14-21(15-11-17)31(2,27)28)24(25(26)30-23)19-6-4-3-5-7-19/h3-16H,1-2H3 JFSOAPWHDSIWHR-UHFFFAOYSA-N 50150750 4-(4-Methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-3-phenyl-pyran-2-one::CHEMBL189133 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150750&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11441846 104039109 CHEMBL189133 ZINC13581306 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276613 COc1ccc(cc1)-c1cc(-c2ccc(cc2)S(C)(=O)=O)c(-c2cccnc2)c(=O)o1 InChI=1S/C24H19NO5S/c1-29-19-9-5-17(6-10-19)22-14-21(16-7-11-20(12-8-16)31(2,27)28)23(24(26)30-22)18-4-3-13-25-15-18/h3-15H,1-2H3 YXJSTNUTCIAVAH-UHFFFAOYSA-N 50150728 4-(4-Methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-3-pyridin-3-yl-pyran-2-one::CHEMBL365497 Prostaglandin G/H synthase 2 Ovis aries 1600 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150728&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11476000 104039087 CHEMBL365497 ZINC13581332 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50276614 CS(=O)(=O)c1ccc(cc1)-c1cc(oc(=O)c1-c1ccccc1)-c1ccc(F)cc1 InChI=1S/C24H17FO4S/c1-30(27,28)20-13-9-16(10-14-20)21-15-22(17-7-11-19(25)12-8-17)29-24(26)23(21)18-5-3-2-4-6-18/h2-15H,1H3 ZRSWEQHAUDNIHG-UHFFFAOYSA-N 50150751 6-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-3-phenyl-pyran-2-one::CHEMBL433562 Prostaglandin G/H synthase 2 Ovis aries 70.0 ChEMBL 10.1021/jm049939b 10.7270/Q22F7MXX 15267236 Rao, PN; Uddin, MJ; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150751&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11281569 104039110 CHEMBL433562 ZINC13581310 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263663 CCC(=C(c1ccccc1)c1ccccc1)c1ccc(cc1)S(=O)(=O)OC InChI=1S/C23H22O3S/c1-3-22(18-14-16-21(17-15-18)27(24,25)26-2)23(19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-17H,3H2,1-2H3 VZAZBBXPIDCFOP-UHFFFAOYSA-N 50143474 4-(1-Benzhydrylidene-propyl)-benzenesulfonic acid methyl ester::CHEMBL450879 Prostaglandin G/H synthase 2 Ovis aries 1250 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143474&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386806 104032668 CHEMBL450879 ZINC28097701 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263665 CCCCCCC(=C(c1ccccc1)c1ccccc1)c1ccc(cc1)S(=O)(=O)OC InChI=1S/C27H30O3S/c1-3-4-5-12-17-26(22-18-20-25(21-19-22)31(28,29)30-2)27(23-13-8-6-9-14-23)24-15-10-7-11-16-24/h6-11,13-16,18-21H,3-5,12,17H2,1-2H3 VKVFVOWWKCPKMH-UHFFFAOYSA-N 50143475 4-(1-Benzhydrylidene-heptyl)-benzenesulfonic acid methyl ester::CHEMBL175686 Prostaglandin G/H synthase 2 Ovis aries 31 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143475&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44387227 104032669 CHEMBL175686 ZINC28110137 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263668 CCCCCC(=C(c1ccccc1)c1ccccc1)c1ccc(cc1)S(=O)(=O)OC InChI=1S/C26H28O3S/c1-3-4-7-16-25(21-17-19-24(20-18-21)30(27,28)29-2)26(22-12-8-5-9-13-22)23-14-10-6-11-15-23/h5-6,8-15,17-20H,3-4,7,16H2,1-2H3 UOOBMYPJLQBYNK-UHFFFAOYSA-N 50143478 4-(1-Benzhydrylidene-hexyl)-benzenesulfonic acid methyl ester::CHEMBL177719 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143478&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44387000 104032672 CHEMBL177719 ZINC28101432 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263670 CCCCCCCCCC(=C(c1ccccc1)c1ccccc1)c1ccc(cc1)S(=O)(=O)OC InChI=1S/C30H36O3S/c1-3-4-5-6-7-8-15-20-29(25-21-23-28(24-22-25)34(31,32)33-2)30(26-16-11-9-12-17-26)27-18-13-10-14-19-27/h9-14,16-19,21-24H,3-8,15,20H2,1-2H3 PXWVXAFLZFNBGY-UHFFFAOYSA-N 50143477 4-(1-Benzhydrylidene-decyl)-benzenesulfonic acid methyl ester::CHEMBL176382 Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143477&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44387029 104032671 CHEMBL176382 ZINC36126979 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263671 COS(=O)(=O)c1ccc(cc1)C(C)=C(c1ccccc1)c1ccccc1 InChI=1S/C22H20O3S/c1-17(18-13-15-21(16-14-18)26(23,24)25-2)22(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-16H,1-2H3 YYGOKGIDPADMQP-UHFFFAOYSA-N 50143479 4-(1-Methyl-2,2-diphenyl-vinyl)-benzenesulfonic acid methyl ester::CHEMBL174756 Prostaglandin G/H synthase 2 Ovis aries 630 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143479&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386654 104032673 CHEMBL174756 ZINC28097142 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263673 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 57.0 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263674 CCCCC(=C(c1ccccc1)c1ccccc1)c1ccc(cc1)S(=O)(=O)OC InChI=1S/C25H26O3S/c1-3-4-15-24(20-16-18-23(19-17-20)29(26,27)28-2)25(21-11-7-5-8-12-21)22-13-9-6-10-14-22/h5-14,16-19H,3-4,15H2,1-2H3 GTDOJZMTDFGYAD-UHFFFAOYSA-N 50143476 4-(1-Benzhydrylidene-pentyl)-benzenesulfonic acid methyl ester::CHEMBL369609 Prostaglandin G/H synthase 2 Ovis aries 14 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143476&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44386951 104032670 CHEMBL369609 ZINC28091697 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263676 CCCCCCCCCCCCCCCC(=C(c1ccccc1)c1ccccc1)c1ccc(cc1)S(=O)(=O)OC InChI=1S/C36H48O3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-21-26-35(31-27-29-34(30-28-31)40(37,38)39-2)36(32-22-17-15-18-23-32)33-24-19-16-20-25-33/h15-20,22-25,27-30H,3-14,21,26H2,1-2H3 APQAAFSQNLMSDJ-UHFFFAOYSA-N 50143480 4-(1-Benzhydrylidene-hexadecyl)-benzenesulfonic acid methyl ester::CHEMBL175028 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143480&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44387091 104032674 CHEMBL175028 ZINC43443391 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50263679 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 430.0 ChEMBL 10.1016/j.bmcl.2004.01.075 10.7270/Q24F1Q46 15050635 Uddin, MJ; Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50265793 Cc1ccc(o1)-c1nc2ccccc2n1CC(=O)NN InChI=1S/C14H14N4O2/c1-9-6-7-12(20-9)14-16-10-4-2-3-5-11(10)18(14)8-13(19)17-15/h2-7H,8,15H2,1H3,(H,17,19) ZZCBCARUXQQBOI-UHFFFAOYSA-N 50044256 CHEMBL3337482 Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.1016/j.ejmech.2014.01.063 10.7270/Q2BK1F0B 24576797 Temirak, A; Shaker, YM; Ragab, FA; Ali, MM; Ali, HI; El Diwani, HI National Research Centre, Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044256&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118714721 313068151 CHEMBL3337482 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286911 CCCC\C(=C(/c1ccccc1)c1ccc(cc1)S(C)(=O)=O)c1ccc(OC(C)=O)cc1 InChI=1S/C27H28O4S/c1-4-5-11-26(21-12-16-24(17-13-21)31-20(2)28)27(22-9-7-6-8-10-22)23-14-18-25(19-15-23)32(3,29)30/h6-10,12-19H,4-5,11H2,1-3H3/b27-26- GSVYNSQUYAMYGY-RQZHXJHFSA-N 50156239 Acetic acid 4-{1-[1-(4-methanesulfonyl-phenyl)-1-phenyl-meth-(Z)-ylidene]-pentyl}-phenyl ester::CHEMBL187654 Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156239&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11178403 104043434 CHEMBL187654 ZINC13585501 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286912 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286917 CCCCCCCC\C(=C(/c1ccccc1)c1ccc(cc1)S(C)(=O)=O)c1ccccc1 InChI=1S/C29H34O2S/c1-3-4-5-6-7-14-19-28(24-15-10-8-11-16-24)29(25-17-12-9-13-18-25)26-20-22-27(23-21-26)32(2,30)31/h8-13,15-18,20-23H,3-7,14,19H2,1-2H3/b29-28- MSQATXNWZSMZKT-ZIADKAODSA-N 50156243 1-((Z)-1,2-Diphenyl-dec-1-enyl)-4-methanesulfonyl-benzene::CHEMBL187384 Prostaglandin G/H synthase 2 Ovis aries 3100 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156243&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11430754 104043438 CHEMBL187384 ZINC36126984 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286920 CC\C(=C(/c1ccccc1)c1ccc(cc1)S(C)(=O)=O)c1ccccc1 InChI=1S/C23H22O2S/c1-3-22(18-10-6-4-7-11-18)23(19-12-8-5-9-13-19)20-14-16-21(17-15-20)26(2,24)25/h4-17H,3H2,1-2H3/b23-22- PFWWRKICQHMOAR-FCQUAONHSA-N 50156240 1-((Z)-1,2-Diphenyl-but-1-enyl)-4-methanesulfonyl-benzene::CHEMBL364663 Prostaglandin G/H synthase 2 Ovis aries 3200 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156240&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11772870 104043435 CHEMBL364663 ZINC13585492 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286921 CCCC\C(=C(/c1ccccc1)c1ccc(cc1)S(C)(=O)=O)c1ccccc1 InChI=1S/C25H26O2S/c1-3-4-15-24(20-11-7-5-8-12-20)25(21-13-9-6-10-14-21)22-16-18-23(19-17-22)28(2,26)27/h5-14,16-19H,3-4,15H2,1-2H3/b25-24- STGWPHUHCYHBDP-IZHYLOQSSA-N 50156245 1-((Z)-1,2-Diphenyl-hex-1-enyl)-4-methanesulfonyl-benzene::CHEMBL188624 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156245&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11773712 104043440 CHEMBL188624 ZINC13585496 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286922 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70.0 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286923 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286926 CCC\C(=C(/c1ccccc1)c1ccc(cc1)S(C)(=O)=O)c1ccccc1 InChI=1S/C24H24O2S/c1-3-10-23(19-11-6-4-7-12-19)24(20-13-8-5-9-14-20)21-15-17-22(18-16-21)27(2,25)26/h4-9,11-18H,3,10H2,1-2H3/b24-23- NNRYGGFTEVJTIV-VHXPQNKSSA-N 50156241 1-((Z)-1,2-Diphenyl-pent-1-enyl)-4-methanesulfonyl-benzene::CHEMBL365432 Prostaglandin G/H synthase 2 Ovis aries 2800 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156241&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11303412 104043436 CHEMBL365432 ZINC13585494 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286927 CC\C(=C(/c1ccccc1)c1ccc(cc1)S(C)(=O)=O)c1ccc(OC(C)=O)cc1 InChI=1S/C25H24O4S/c1-4-24(19-10-14-22(15-11-19)29-18(2)26)25(20-8-6-5-7-9-20)21-12-16-23(17-13-21)30(3,27)28/h5-17H,4H2,1-3H3/b25-24- ZOXHROWEZOQRRD-IZHYLOQSSA-N 50156244 Acetic acid 4-{1-[1-(4-methanesulfonyl-phenyl)-1-phenyl-meth-(Z)-ylidene]-propyl}-phenyl ester::CHEMBL370265 Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156244&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11362161 104043439 CHEMBL370265 ZINC13585499 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50286930 CCCCCC\C(=C(/c1ccccc1)c1ccc(cc1)S(C)(=O)=O)c1ccccc1 InChI=1S/C27H30O2S/c1-3-4-5-12-17-26(22-13-8-6-9-14-22)27(23-15-10-7-11-16-23)24-18-20-25(21-19-24)30(2,28)29/h6-11,13-16,18-21H,3-5,12,17H2,1-2H3/b27-26- PCYCJSPLWWNDPF-RQZHXJHFSA-N 50156242 1-((Z)-1,2-Diphenyl-oct-1-enyl)-4-methanesulfonyl-benzene::CHEMBL187391 Prostaglandin G/H synthase 2 Ovis aries 420 ChEMBL 10.1021/jm049523y 10.7270/Q2MG7P0Z 15537365 Uddin, MJ; Praveen Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156242&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11247111 104043437 CHEMBL187391 ZINC13585497 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291334 CC(=O)N1CCN(CC1)c1c(\C=N\Nc2nc3ccccc3nc2O)c(C)nn1-c1ccccc1 InChI=1S/C25H26N8O2/c1-17-20(16-26-29-23-24(35)28-22-11-7-6-10-21(22)27-23)25(32-14-12-31(13-15-32)18(2)34)33(30-17)19-8-4-3-5-9-19/h3-11,16H,12-15H2,1-2H3,(H,27,29)(H,28,35)/b26-16+ GFECJSAJCVJBKE-WGOQTCKBSA-N 50058832 CHEMBL3325875 Prostaglandin G/H synthase 2 Ovis aries 460 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058832&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711239 103954734 CHEMBL3325875 ZINC26173178 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291335 Cc1nn(c(N2CCNCC2)c1\C=N\Nc1nc2ccccc2nc1O)-c1ccccc1 InChI=1S/C23H24N8O/c1-16-18(15-25-28-21-22(32)27-20-10-6-5-9-19(20)26-21)23(30-13-11-24-12-14-30)31(29-16)17-7-3-2-4-8-17/h2-10,15,24H,11-14H2,1H3,(H,26,28)(H,27,32)/b25-15+ SGWFIJSYEOLUGL-MFKUBSTISA-N 50058833 CHEMBL3325874 Prostaglandin G/H synthase 2 Ovis aries 16000 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058833&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711238 103954735 CHEMBL3325874 ZINC26164757 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291336 Cc1nn(c(N2CCCCC2)c1\C=N\Nc1nc2ccccc2nc1O)-c1ccccc1 InChI=1S/C24H25N7O/c1-17-19(16-25-28-22-23(32)27-21-13-7-6-12-20(21)26-22)24(30-14-8-3-9-15-30)31(29-17)18-10-4-2-5-11-18/h2,4-7,10-13,16H,3,8-9,14-15H2,1H3,(H,26,28)(H,27,32)/b25-16+ HGSCZPFYZGNCLI-PCLIKHOPSA-N 50058834 CHEMBL3325873 Prostaglandin G/H synthase 2 Ovis aries 22000 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058834&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711237 103954736 CHEMBL3325873 ZINC13763200 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291337 Cc1nn(c(N2CCOCC2)c1\C=N\Nc1nc2ccccc2nc1O)-c1ccccc1 InChI=1S/C23H23N7O2/c1-16-18(15-24-27-21-22(31)26-20-10-6-5-9-19(20)25-21)23(29-11-13-32-14-12-29)30(28-16)17-7-3-2-4-8-17/h2-10,15H,11-14H2,1H3,(H,25,27)(H,26,31)/b24-15+ UCWKAKPLVUTIMU-BUVRLJJBSA-N 50058835 CHEMBL3325872 Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058835&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711236 103954737 CHEMBL3325872 ZINC13763202 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291348 CN1CCN(CC1)c1c(\C=N\Nc2nc3ccccc3nc2O)c(C)nn1-c1ccccc1 InChI=1S/C24H26N8O/c1-17-19(16-25-28-22-23(33)27-21-11-7-6-10-20(21)26-22)24(31-14-12-30(2)13-15-31)32(29-17)18-8-4-3-5-9-18/h3-11,16H,12-15H2,1-2H3,(H,26,28)(H,27,33)/b25-16+ UEVINHQDOKZMCM-PCLIKHOPSA-N 50058839 CHEMBL3325729 Prostaglandin G/H synthase 2 Ovis aries 480 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058839&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711145 103954741 CHEMBL3325729 ZINC13763196 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291349 Cc1nn(c(OC2CCCC2)c1\C=N\Nc1nc2ccccc2nc1O)-c1ccccc1 InChI=1S/C24H24N6O2/c1-16-19(15-25-28-22-23(31)27-21-14-8-7-13-20(21)26-22)24(32-18-11-5-6-12-18)30(29-16)17-9-3-2-4-10-17/h2-4,7-10,13-15,18H,5-6,11-12H2,1H3,(H,26,28)(H,27,31)/b25-15+ NZGOUMAHKNZUIT-MFKUBSTISA-N 50058838 CHEMBL3325730 Prostaglandin G/H synthase 2 Ovis aries 8500 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058838&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711146 103954740 CHEMBL3325730 ZINC13763206 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291350 CN(C)c1c(\C=N\Nc2nc3ccccc3nc2O)c(C)nn1-c1ccccc1 InChI=1S/C21H21N7O/c1-14-16(21(27(2)3)28(26-14)15-9-5-4-6-10-15)13-22-25-19-20(29)24-18-12-8-7-11-17(18)23-19/h4-13H,1-3H3,(H,23,25)(H,24,29)/b22-13+ WWNUJJQXWCKCJX-LPYMAVHISA-N 50058837 CHEMBL3325733 Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058837&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711149 103954739 CHEMBL3325733 ZINC13763198 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291351 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 280 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50291338 Cc1nn(c(Cl)c1\C=N\Nc1nc2ccccc2[nH]c1=O)-c1ccccc1 InChI=1S/C19H15ClN6O/c1-12-14(17(20)26(25-12)13-7-3-2-4-8-13)11-21-24-18-19(27)23-16-10-6-5-9-15(16)22-18/h2-11H,1H3,(H,22,24)(H,23,27)/b21-11+ TYZNQCNJYPBIKM-SRZZPIQSSA-N 50058836 CHEMBL3325870 Prostaglandin G/H synthase 2 Ovis aries 32000 ChEMBL 10.1016/j.ejmech.2014.08.048 10.7270/Q2GQ70D7 25147154 Galal, SA; Khairat, SH; Ragab, FA; Abdelsamie, AS; Ali, MM; Soliman, SM; Mortier, J; Wolber, G; El Diwani, HI Dokki http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058836&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118711234 103954738 CHEMBL3325870 ZINC00006897 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50280554 CCCCCC\C(=C/c1ccccc1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H26O2S/c1-3-4-5-9-12-20(17-18-10-7-6-8-11-18)19-13-15-21(16-14-19)24(2,22)23/h6-8,10-11,13-17H,3-5,9,12H2,1-2H3/b20-17+ KLEINUAKRSRGRN-LVZFUZTISA-N 50152543 1-[(E)-1-hexyl-2-phenylvinyl]-4-(methylsulfonyl)benzene::CHEMBL187145 Prostaglandin G/H synthase 2 Ovis aries 770 ChEMBL 10.1016/j.bmcl.2004.07.027 10.7270/Q2348JVS 15341950 Uddin, MJ; Rao, PN; Rahim, MA; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152543&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10472572 104040608 CHEMBL187145 ZINC28390273 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50280555 CC\C(=C/c1ccccc1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C17H18O2S/c1-3-15(13-14-7-5-4-6-8-14)16-9-11-17(12-10-16)20(2,18)19/h4-13H,3H2,1-2H3/b15-13+ IPCCPBABKOALOL-FYWRMAATSA-N 50152544 1-[(E)-1-ethyl-2-phenylvinyl]-4-(methylsulfonyl)benzene::CHEMBL365288 Prostaglandin G/H synthase 2 Ovis aries 8000 ChEMBL 10.1016/j.bmcl.2004.07.027 10.7270/Q2348JVS 15341950 Uddin, MJ; Rao, PN; Rahim, MA; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152544&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44394298 104040609 CHEMBL365288 ZINC28382920 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50280558 CCC\C(=C/c1ccccc1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C18H20O2S/c1-3-7-17(14-15-8-5-4-6-9-15)16-10-12-18(13-11-16)21(2,19)20/h4-6,8-14H,3,7H2,1-2H3/b17-14+ IKRJTJAXZJVDAH-SAPNQHFASA-N 50152547 1-(methylsulfonyl)-4-[(E)-2-phenyl-1-propylvinyl]benzene::CHEMBL187481 Prostaglandin G/H synthase 2 Ovis aries 3100 ChEMBL 10.1016/j.bmcl.2004.07.027 10.7270/Q2348JVS 15341950 Uddin, MJ; Rao, PN; Rahim, MA; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152547&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44394429 104040612 CHEMBL187481 ZINC28390269 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50280562 CCCCCCC\C(=C/c1ccccc1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C22H28O2S/c1-3-4-5-6-10-13-21(18-19-11-8-7-9-12-19)20-14-16-22(17-15-20)25(2,23)24/h7-9,11-12,14-18H,3-6,10,13H2,1-2H3/b21-18+ XWFGDAXZUZIQCJ-DYTRJAOYSA-N 50152546 1-[(E)-1-octyl-2-phenylvinyl]-4-(methylsulfonyl)benzene::CHEMBL365615 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.bmcl.2004.07.027 10.7270/Q2348JVS 15341950 Uddin, MJ; Rao, PN; Rahim, MA; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152546&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44394402 104040611 CHEMBL365615 ZINC36126981 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50280563 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70.0 ChEMBL 10.1016/j.bmcl.2004.07.027 10.7270/Q2348JVS 15341950 Uddin, MJ; Rao, PN; Rahim, MA; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50280565 CC\C(=C/c1ccc(C)cc1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C18H20O2S/c1-4-16(13-15-7-5-14(2)6-8-15)17-9-11-18(12-10-17)21(3,19)20/h5-13H,4H2,1-3H3/b16-13+ VVLBPWQWFNCKLO-DTQAZKPQSA-N 50152545 1-[(E)-1-ethyl-2-(4-methylphenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL184374 Prostaglandin G/H synthase 2 Ovis aries 31000 ChEMBL 10.1016/j.bmcl.2004.07.027 10.7270/Q2348JVS 15341950 Uddin, MJ; Rao, PN; Rahim, MA; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152545&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44394299 104040610 CHEMBL184374 ZINC28382926 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50280567 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmcl.2004.07.027 10.7270/Q2348JVS 15341950 Uddin, MJ; Rao, PN; Rahim, MA; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290361 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccccc1)\c1ccccc1 InChI=1S/C21H18O2S/c1-24(22,23)20-14-12-19(13-15-20)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-16H,1H3/b21-16+ ZPQRRDVDLPNHQM-LTGZKZEYSA-N 50158188 1-(1,2-Diphenyl-vinyl)-4-methanesulfonyl-benzene::CHEMBL178355 Prostaglandin G/H synthase 2 Ovis aries 130 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158188&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388871 104044973 CHEMBL178355 ZINC28123186 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290364 CS(=O)(=O)c1ccc(C=C(c2ccc(F)cc2)c2ccc(F)cc2)cc1 InChI=1S/C21H16F2O2S/c1-26(24,25)20-12-2-15(3-13-20)14-21(16-4-8-18(22)9-5-16)17-6-10-19(23)11-7-17/h2-14H,1H3 AAXDKCSQCFEDKK-UHFFFAOYSA-N 50158192 1-[2,2-bis(4-fluorophenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL179723 Prostaglandin G/H synthase 2 Ovis aries 32000 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158192&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388803 104044977 CHEMBL179723 ZINC28120617 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290365 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccc(F)cc1)\c1ccccc1 InChI=1S/C21H17FO2S/c1-25(23,24)20-13-9-18(10-14-20)21(17-5-3-2-4-6-17)15-16-7-11-19(22)12-8-16/h2-15H,1H3/b21-15+ BDWYSYFYONHNGL-RCCKNPSSSA-N 50158187 1-fluoro-4-{(E)-2-[4-(methylsulfonyl)phenyl]-2-phenylvinyl}benzene::CHEMBL360720 Prostaglandin G/H synthase 2 Ovis aries 32 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158187&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11291120 104044972 CHEMBL360720 ZINC28126591 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290371 Cc1ccc(\C=C(/c2ccccc2)c2ccc(cc2)S(C)(=O)=O)cc1 InChI=1S/C22H20O2S/c1-17-8-10-18(11-9-17)16-22(19-6-4-3-5-7-19)20-12-14-21(15-13-20)25(2,23)24/h3-16H,1-2H3/b22-16+ OKYHBSFDSASVNT-CJLVFECKSA-N 50158191 1-methyl-4-{(E)-2-[4-(methylsulfonyl)phenyl]-2-phenylvinyl}benzene::CHEMBL178356 Prostaglandin G/H synthase 2 Ovis aries 1200 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158191&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388872 104044976 CHEMBL178356 ZINC28123193 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290372 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccc(Cl)cc1)\c1ccccc1 InChI=1S/C21H17ClO2S/c1-25(23,24)20-13-9-18(10-14-20)21(17-5-3-2-4-6-17)15-16-7-11-19(22)12-8-16/h2-15H,1H3/b21-15+ SSJFWOVZCDSXFK-RCCKNPSSSA-N 50158193 1-chloro-4-{(E)-2-[4-(methylsulfonyl)phenyl]-2-phenylvinyl}benzene::CHEMBL360310 Prostaglandin G/H synthase 2 Ovis aries 114 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158193&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388916 104044978 CHEMBL360310 ZINC28124460 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290374 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70.0 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290375 Cc1ccc(cc1)C(=Cc1ccc(cc1)S(C)(=O)=O)c1ccc(C)cc1 InChI=1S/C23H22O2S/c1-17-4-10-20(11-5-17)23(21-12-6-18(2)7-13-21)16-19-8-14-22(15-9-19)26(3,24)25/h4-16H,1-3H3 RAQUSUKRSYUEMK-UHFFFAOYSA-N 50158194 1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL179204 Prostaglandin G/H synthase 2 Ovis aries 31000 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158194&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388920 104044979 CHEMBL179204 ZINC28118396 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290379 CS(=O)(=O)c1ccc(C=C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1 InChI=1S/C21H16Cl2O2S/c1-26(24,25)20-12-2-15(3-13-20)14-21(16-4-8-18(22)9-5-16)17-6-10-19(23)11-7-17/h2-14H,1H3 QZMXDJPBJZDNMK-UHFFFAOYSA-N 50158189 1-[2,2-bis(4-chlorophenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL361848 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158189&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388811 104044974 CHEMBL361848 ZINC28120468 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290388 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50290393 CS(=O)(=O)c1ccc(cc1)C(=C\c1ccc(F)c(F)c1)\c1ccccc1 InChI=1S/C21H16F2O2S/c1-26(24,25)18-10-8-17(9-11-18)19(16-5-3-2-4-6-16)13-15-7-12-20(22)21(23)14-15/h2-14H,1H3/b19-13+ YRBVPLSHFFJSHS-CPNJWEJPSA-N 50158190 1,2-Difluoro-4-[2-(4-methanesulfonyl-phenyl)-2-phenyl-vinyl]-benzene::CHEMBL426955 Prostaglandin G/H synthase 2 Ovis aries 790.0 ChEMBL 10.1016/j.bmcl.2004.10.050 10.7270/Q2GF0T0C 15603969 Uddin, MJ; Rao, PN; McDonald, R; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158190&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44388897 104044975 CHEMBL426955 ZINC28122813 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310099 COc1cc(CN2C(=O)c3ccccc3C2=O)cc(OC)c1OC InChI=1S/C18H17NO5/c1-22-14-8-11(9-15(23-2)16(14)24-3)10-19-17(20)12-6-4-5-7-13(12)18(19)21/h4-9H,10H2,1-3H3 RPGRHGPHWFRJGI-UHFFFAOYSA-N 50070500 CHEMBL3408773 Prostaglandin G/H synthase 2 Ovis aries 33800 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070500&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 12250372 103964365 CHEMBL3408773 ZINC29251383 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310100 COc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C16H13NO3/c1-20-12-8-6-11(7-9-12)10-17-15(18)13-4-2-3-5-14(13)16(17)19/h2-9H,10H2,1H3 KBSAUETWMISGCC-UHFFFAOYSA-N 50070498 CHEMBL1594493 Prostaglandin G/H synthase 2 Ovis aries 40100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070498&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 519849 103964363 CHEMBL1594493 ZINC29251408 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310101 Fc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C15H10FNO2/c16-11-7-5-10(6-8-11)9-17-14(18)12-3-1-2-4-13(12)15(17)19/h1-8H,9H2 WBYPZQIEVABAGS-UHFFFAOYSA-N 50070493 CHEMBL3408774 Prostaglandin G/H synthase 2 Ovis aries 68600 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070493&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2774444 103964358 CHEMBL3408774 ZINC01894985 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310102 COc1cc(CN2C(=O)c3ccc(C)cc3C2=O)cc(OC)c1OC InChI=1S/C19H19NO5/c1-11-5-6-13-14(7-11)19(22)20(18(13)21)10-12-8-15(23-2)17(25-4)16(9-12)24-3/h5-9H,10H2,1-4H3 CVTIIWYEXAPUHO-UHFFFAOYSA-N 50070492 CHEMBL3408775 Prostaglandin G/H synthase 2 Ovis aries 24000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070492&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731147 103964357 CHEMBL3408775 ZINC29247920 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310103 COc1ccc(CN2C(=O)c3ccc(C)cc3C2=O)cc1 InChI=1S/C17H15NO3/c1-11-3-8-14-15(9-11)17(20)18(16(14)19)10-12-4-6-13(21-2)7-5-12/h3-9H,10H2,1-2H3 PTCDANKRMHTDCO-UHFFFAOYSA-N 50070491 CHEMBL3408776 Prostaglandin G/H synthase 2 Ovis aries 36100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070491&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731148 103964356 CHEMBL3408776 ZINC29246328 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310104 Cc1ccc2C(=O)N(Cc3ccc(F)cc3)C(=O)c2c1 InChI=1S/C16H12FNO2/c1-10-2-7-13-14(8-10)16(20)18(15(13)19)9-11-3-5-12(17)6-4-11/h2-8H,9H2,1H3 PXHZVRHUSZNNBN-UHFFFAOYSA-N 50070490 CHEMBL3408777 Prostaglandin G/H synthase 2 Ovis aries 74000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070490&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731149 103964355 31401 CHEMBL3408777 7148 ZINC01552174 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310105 COc1cc(CN2C(=O)c3ccc(cc3C2=O)C(C)(C)C)cc(OC)c1OC InChI=1S/C22H25NO5/c1-22(2,3)14-7-8-15-16(11-14)21(25)23(20(15)24)12-13-9-17(26-4)19(28-6)18(10-13)27-5/h7-11H,12H2,1-6H3 CPPPPTMRZNWMKL-UHFFFAOYSA-N 50070489 CHEMBL3408778 Prostaglandin G/H synthase 2 Ovis aries 32200 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070489&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731150 103964354 CHEMBL3408778 ZINC29247927 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310106 COc1ccc(CN2C(=O)c3ccc(cc3C2=O)C(C)(C)C)cc1 InChI=1S/C20H21NO3/c1-20(2,3)14-7-10-16-17(11-14)19(23)21(18(16)22)12-13-5-8-15(24-4)9-6-13/h5-11H,12H2,1-4H3 SQBLQJAJWNXGHN-UHFFFAOYSA-N 50070488 CHEMBL3408779 Prostaglandin G/H synthase 2 Ovis aries 29100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070488&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731151 103964353 CHEMBL3408779 ZINC29253658 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310107 CC(C)(C)c1ccc2C(=O)N(Cc3ccc(F)cc3)C(=O)c2c1 InChI=1S/C19H18FNO2/c1-19(2,3)13-6-9-15-16(10-13)18(23)21(17(15)22)11-12-4-7-14(20)8-5-12/h4-10H,11H2,1-3H3 UPKDHUDHTGGVQZ-UHFFFAOYSA-N 50070487 CHEMBL3408780 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070487&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731152 103964352 CHEMBL3408780 ZINC29308492 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310108 COc1cc(CN2C(=O)c3ccc(cc3C2=O)[N+]([O-])=O)cc(OC)c1OC InChI=1S/C18H16N2O7/c1-25-14-6-10(7-15(26-2)16(14)27-3)9-19-17(21)12-5-4-11(20(23)24)8-13(12)18(19)22/h4-8H,9H2,1-3H3 VFVWBGPGUDWLHU-UHFFFAOYSA-N 50070486 CHEMBL3408781 Prostaglandin G/H synthase 2 Ovis aries 180 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070486&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731153 103964351 CHEMBL3408781 ZINC01894982 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310109 COc1ccc(CN2C(=O)c3ccc(cc3C2=O)[N+]([O-])=O)cc1 InChI=1S/C16H12N2O5/c1-23-12-5-2-10(3-6-12)9-17-15(19)13-7-4-11(18(21)22)8-14(13)16(17)20/h2-8H,9H2,1H3 GYEAQZHGHYVSGK-UHFFFAOYSA-N 50070485 CHEMBL3408782 Prostaglandin G/H synthase 2 Ovis aries 240 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070485&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 16797324 103964350 CHEMBL3408782 ZINC29243094 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310110 [O-][N+](=O)c1ccc2C(=O)N(Cc3ccc(F)cc3)C(=O)c2c1 InChI=1S/C15H9FN2O4/c16-10-3-1-9(2-4-10)8-17-14(19)12-6-5-11(18(21)22)7-13(12)15(17)20/h1-7H,8H2 FLMVARQXYYHCKO-UHFFFAOYSA-N 50070484 CHEMBL3408783 Prostaglandin G/H synthase 2 Ovis aries 31100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070484&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 1218988 103964349 CHEMBL3408783 ZINC29231317 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310111 COc1cc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc(OC)c1OC InChI=1S/C18H15Cl2NO5/c1-24-14-4-9(5-15(25-2)16(14)26-3)8-21-17(22)10-6-12(19)13(20)7-11(10)18(21)23/h4-7H,8H2,1-3H3 CIDSGDXZKDZTFH-UHFFFAOYSA-N 50070483 CHEMBL3408784 Prostaglandin G/H synthase 2 Ovis aries 280 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070483&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731154 103964348 CHEMBL3408784 ZINC29246335 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310112 COc1ccc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc1 InChI=1S/C16H11Cl2NO3/c1-22-10-4-2-9(3-5-10)8-19-15(20)11-6-13(17)14(18)7-12(11)16(19)21/h2-7H,8H2,1H3 QSRUHEHUTRHBDP-UHFFFAOYSA-N 50070482 CHEMBL3408785 Prostaglandin G/H synthase 2 Ovis aries 360 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070482&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731155 103964347 CHEMBL3408785 ZINC29306753 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310113 Fc1ccc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc1 InChI=1S/C15H8Cl2FNO2/c16-12-5-10-11(6-13(12)17)15(21)19(14(10)20)7-8-1-3-9(18)4-2-8/h1-6H,7H2 GOESPTLWFXTMKF-UHFFFAOYSA-N 50070481 CHEMBL3408786 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070481&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45713866 103964346 CHEMBL3408786 ZINC29243101 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310114 COc1cc(CN2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc(OC)c1OC InChI=1S/C18H13Cl4NO5/c1-26-8-4-7(5-9(27-2)16(8)28-3)6-23-17(24)10-11(18(23)25)13(20)15(22)14(21)12(10)19/h4-5H,6H2,1-3H3 BJEWGLBROXOOFW-UHFFFAOYSA-N 50070480 CHEMBL3408787 Prostaglandin G/H synthase 2 Ovis aries 30700 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070480&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731156 103964345 CHEMBL3408787 ZINC29254624 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310115 COc1ccc(CN2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1 InChI=1S/C16H9Cl4NO3/c1-24-8-4-2-7(3-5-8)6-21-15(22)9-10(16(21)23)12(18)14(20)13(19)11(9)17/h2-5H,6H2,1H3 WWMOURIEUSVACP-UHFFFAOYSA-N 50070479 CHEMBL3408788 Prostaglandin G/H synthase 2 Ovis aries 4100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070479&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731157 103964344 CHEMBL3408788 ZINC29246781 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310116 Fc1ccc(CN2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1 InChI=1S/C15H6Cl4FNO2/c16-10-8-9(11(17)13(19)12(10)18)15(23)21(14(8)22)5-6-1-3-7(20)4-2-6/h1-4H,5H2 XZZIFOYYBUVRFW-UHFFFAOYSA-N 50070478 CHEMBL3408789 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070478&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731158 313072410 CHEMBL3408789 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310117 COc1cc(CN2C(=O)c3nccnc3C2=O)cc(OC)c1OC InChI=1S/C16H15N3O5/c1-22-10-6-9(7-11(23-2)14(10)24-3)8-19-15(20)12-13(16(19)21)18-5-4-17-12/h4-7H,8H2,1-3H3 QWLFCIQLKPEPRR-UHFFFAOYSA-N 50070477 CHEMBL3408790 Prostaglandin G/H synthase 2 Ovis aries 8500 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070477&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731159 103964343 CHEMBL3408790 ZINC03916870 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310118 COc1ccc(CN2C(=O)c3nccnc3C2=O)cc1 InChI=1S/C14H11N3O3/c1-20-10-4-2-9(3-5-10)8-17-13(18)11-12(14(17)19)16-7-6-15-11/h2-7H,8H2,1H3 MJJJYCDTFZMZDH-UHFFFAOYSA-N 50070475 CHEMBL433813 Prostaglandin G/H synthase 2 Ovis aries 38700 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070475&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 16724718 103964341 51221 CHEMBL433813 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310119 Fc1ccc(CN2C(=O)c3nccnc3C2=O)cc1 InChI=1S/C13H8FN3O2/c14-9-3-1-8(2-4-9)7-17-12(18)10-11(13(17)19)16-6-5-15-10/h1-6H,7H2 MEVVJOOKXVSDOL-UHFFFAOYSA-N 50070474 CHEMBL3408791 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070474&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731160 103964340 CHEMBL3408791 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310120 COc1cc(CN2C(=O)c3cccc4cccc(C2=O)c34)cc(OC)c1OC InChI=1S/C22H19NO5/c1-26-17-10-13(11-18(27-2)20(17)28-3)12-23-21(24)15-8-4-6-14-7-5-9-16(19(14)15)22(23)25/h4-11H,12H2,1-3H3 GIKVMAADTSFMLL-UHFFFAOYSA-N 50070433 CHEMBL3408792 Prostaglandin G/H synthase 2 Ovis aries 7300 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070433&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731161 313048452 CHEMBL3408792 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310121 COc1ccc(CN2C(=O)c3cccc4cccc(C2=O)c34)cc1 InChI=1S/C20H15NO3/c1-24-15-10-8-13(9-11-15)12-21-19(22)16-6-2-4-14-5-3-7-17(18(14)16)20(21)23/h2-11H,12H2,1H3 IQOALYXGGXPZQO-UHFFFAOYSA-N 50070432 CHEMBL1299386 Prostaglandin G/H synthase 2 Ovis aries 17100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070432&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2939282 313072409 CHEMBL1299386 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310122 Fc1ccc(CN2C(=O)c3cccc4cccc(C2=O)c34)cc1 InChI=1S/C19H12FNO2/c20-14-9-7-12(8-10-14)11-21-18(22)15-5-1-3-13-4-2-6-16(17(13)15)19(21)23/h1-10H,11H2 JVHUQBLLHSIOMR-UHFFFAOYSA-N 50070431 CHEMBL3408793 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070431&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10614509 313048451 CHEMBL3408793 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310123 COc1cc(cc(OC)c1OC)N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O InChI=1S/C17H14N2O7/c1-24-13-7-10(8-14(25-2)15(13)26-3)18-16(20)11-5-4-9(19(22)23)6-12(11)17(18)21/h4-8H,1-3H3 FCQFHRMDZZRIPV-UHFFFAOYSA-N 50342799 5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770585 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342799&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 52952951 131345735 CHEMBL1770585 ZINC71334509 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310124 OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) DCOPUUMXTXDBNB-UHFFFAOYSA-N 13066 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid::CHEMBL139::Diclofenac::US11337935, Compound Diclofenac::US11478464, Compound Diclofenac::{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid Prostaglandin G/H synthase 2 Ovis aries 4200 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13066&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search DIF 1NR6,5U1R,3N8Y,1SV9,3CFQ,4OJ4,4XTA,2WEK,1DVX,8BSG,1PXX,5DBY,2B17,3IB0,4ZBQ,4ZBR,4Z69,4UBS,6HN0,6HN1 3033 46513484 47381 CHEMBL139 DB00586 2714 C01690 ZINC00001281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310125 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 260 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310630 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310632 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCO\N=[N+](/[O-])N(C)C)c2c1 InChI=1S/C22H23ClN4O6/c1-14-18(12-21(28)32-13-33-24-27(30)25(2)3)19-11-17(31-4)9-10-20(19)26(14)22(29)15-5-7-16(23)8-6-15/h5-11H,12-13H2,1-4H3/b27-24- LRFOMIMOOPCTBY-PNHLSOANSA-N 50168441 ({[(1Z)-2,2-dimethyl-1-oxidohydrazono]amino}oxy)methyl (1-para-chlorobenzoyl-2-methyl-5-methoxy-1H-indol-3-yl)acetate::CHEMBL448156 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168441&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11340481 104053420 CHEMBL448156 ZINC13645635 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310633 CC(=O)Oc1ccccc1C(=O)OCO\N=[N+](/[O-])N1CCCC1 InChI=1S/C14H17N3O6/c1-11(18)23-13-7-3-2-6-12(13)14(19)21-10-22-15-17(20)16-8-4-5-9-16/h2-3,6-7H,4-5,8-10H2,1H3/b17-15- GQYASZUFOLJZBK-ICFOKQHNSA-N 50168440 CHEMBL373231::{[(Z)-2-oxido-2-pyrrolidin-1-yldiazenyl]oxy}methyl 2-(acetyloxy)benzoate Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168440&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11381710 104053419 CHEMBL373231 ZINC13645607 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310635 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 5700 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310636 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCO\N=[N+](/[O-])N3CCCC3)c2c1 InChI=1S/C24H25ClN4O6/c1-16-20(14-23(30)34-15-35-26-29(32)27-11-3-4-12-27)21-13-19(33-2)9-10-22(21)28(16)24(31)17-5-7-18(25)8-6-17/h5-10,13H,3-4,11-12,14-15H2,1-2H3/b29-26- LCHVKQXIWFWJBC-WCTVFOPTSA-N 50168438 CHEMBL192081::{[(Z)-2-oxido-2-pyrrolidin-1-yldiazenyl]oxy}methyl (1-para-chlorobenzoyl-2-methyl-5-methoxy-1H-indol-3-yl)acetate Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168438&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11295010 104053417 CHEMBL192081 ZINC13645630 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310637 CC(C)Cc1ccc(cc1)C(C)C(=O)OCO\N=[N+](/[O-])N(C)C InChI=1S/C16H25N3O4/c1-12(2)10-14-6-8-15(9-7-14)13(3)16(20)22-11-23-17-19(21)18(4)5/h6-9,12-13H,10-11H2,1-5H3/b19-17- GUPNQDAVUGSUQK-ZPHPHTNESA-N 50168439 ({[(1Z)-2,2-dimethyl-1-oxidohydrazono]amino}oxy)methyl 2-(4-isobutylphenyl)propanoate::CHEMBL434725 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168439&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11267269 104053418 CHEMBL434725 ZINC13645626 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310638 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310639 CN(C)[N+](\[O-])=N\OCOC(=O)c1ccccc1OC(C)=O InChI=1S/C12H15N3O6/c1-9(16)21-11-7-5-4-6-10(11)12(17)19-8-20-13-15(18)14(2)3/h4-7H,8H2,1-3H3/b15-13- FCWHFPMBKVUDNL-SQFISAMPSA-N 50168442 ({[(1Z)-2,2-dimethyl-1-oxidohydrazono]amino}oxy)methyl 2-(acetyloxy)benzoate::CHEMBL195388 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168442&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11426474 104053421 CHEMBL195388 ZINC13645610 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310642 CC(C)Cc1ccc(cc1)C(C)C(=O)OCO\N=[N+](/[O-])N1CCCC1 InChI=1S/C18H27N3O4/c1-14(2)12-16-6-8-17(9-7-16)15(3)18(22)24-13-25-19-21(23)20-10-4-5-11-20/h6-9,14-15H,4-5,10-13H2,1-3H3/b21-19- JSRCNCYDUYCLNS-VZCXRCSSSA-N 50168437 CHEMBL192558::{[(Z)-2-oxido-2-pyrrolidin-1-yldiazenyl]oxy}methyl 2-(4-isobutylphenyl)propanoate Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1021/jm050211k 10.7270/Q2FX790B 15943479 Velazquez, C; Praveen Rao, PN; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168437&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11393955 104053416 CHEMBL192558 ZINC13645618 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310060 Fc1ccc(CN2C(=O)C3CC=CCC3C2=O)cc1 InChI=1S/C15H14FNO2/c16-11-7-5-10(6-8-11)9-17-14(18)12-3-1-2-4-13(12)15(17)19/h1-2,5-8,12-13H,3-4,9H2 RNAIGUHTRRILRE-UHFFFAOYSA-N 50070425 CHEMBL3408772 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070425&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42902531 313072405 CHEMBL3408772 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310061 COc1ccc(CN2C(=O)C3CC=CCC3C2=O)cc1 InChI=1S/C16H17NO3/c1-20-12-8-6-11(7-9-12)10-17-15(18)13-4-2-3-5-14(13)16(17)19/h2-3,6-9,13-14H,4-5,10H2,1H3 JCDHRPAEWHIXHB-UHFFFAOYSA-N 50070426 CHEMBL3408771 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070426&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 17126473 313048449 CHEMBL3408771 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310062 COc1cc(CN2C(=O)C3CC=CCC3C2=O)cc(OC)c1OC InChI=1S/C18H21NO5/c1-22-14-8-11(9-15(23-2)16(14)24-3)10-19-17(20)12-6-4-5-7-13(12)18(19)21/h4-5,8-9,12-13H,6-7,10H2,1-3H3 OLEYKPKXSABUOM-UHFFFAOYSA-N 50070427 CHEMBL3408770 Prostaglandin G/H synthase 2 Ovis aries 70600 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070427&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 118731146 313072406 CHEMBL3408770 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310063 Fc1ccc(CN2C(=O)CCC2=O)cc1 InChI=1S/C11H10FNO2/c12-9-3-1-8(2-4-9)7-13-10(14)5-6-11(13)15/h1-4H,5-7H2 UWLXBKCBVKMPAD-UHFFFAOYSA-N 50070428 CHEMBL3408769 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070428&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 22510340 313072407 CHEMBL3408769 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310064 COc1ccc(CN2C(=O)CCC2=O)cc1 InChI=1S/C12H13NO3/c1-16-10-4-2-9(3-5-10)8-13-11(14)6-7-12(13)15/h2-5H,6-8H2,1H3 GXYKEWMYCBTVNR-UHFFFAOYSA-N 50070429 CHEMBL3408768 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070429&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 284094 313072408 CHEMBL3408768 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50310065 COc1cc(CN2C(=O)CCC2=O)cc(OC)c1OC InChI=1S/C14H17NO5/c1-18-10-6-9(7-11(19-2)14(10)20-3)8-15-12(16)4-5-13(15)17/h6-7H,4-5,8H2,1-3H3 SUKLTRWYFFLBHO-UHFFFAOYSA-N 50070430 CHEMBL3408767 Prostaglandin G/H synthase 2 Ovis aries 75100 ChEMBL 10.1016/j.ejmech.2014.12.039 10.7270/Q2GH9KN3 25549551 Alanazi, AM; El-Azab, AS; Al-Suwaidan, IA; ElTahir, KE; Asiri, YA; Abdel-Aziz, NI; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070430&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 94287760 313048450 CHEMBL3408767 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50335892 COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)(F)F InChI=1S/C17H12ClF3N2O/c1-24-14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3 PQUGCKBLVKJMNT-UHFFFAOYSA-N 13065 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole::CHEMBL26915::SC-560 Prostaglandin G/H synthase 2 Ovis aries 74900 ChEMBL 10.1016/j.ejmech.2015.02.049 10.7270/Q2416ZRX 25768707 Perrone, MG; Vitale, P; Panella, A; Fortuna, CG; Scilimati, A Universit£ degli Studi di Bari"A. Moro" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13065&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 4306515 46513483 CHEMBL26915 ZINC02391787 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50335893 COc1ccc(cc1)-c1noc(CC(O)=O)c1-c1ccc(OC)cc1 InChI=1S/C19H17NO5/c1-23-14-7-3-12(4-8-14)18-16(11-17(21)22)25-20-19(18)13-5-9-15(24-2)10-6-13/h3-10H,11H2,1-2H3,(H,21,22) DJEIHHYCDCTAAH-UHFFFAOYSA-N 50376383 CHEMBL259972 Prostaglandin G/H synthase 2 Ovis aries 440 ChEMBL 10.1016/j.ejmech.2015.02.049 10.7270/Q2416ZRX 25768707 Perrone, MG; Vitale, P; Panella, A; Fortuna, CG; Scilimati, A Universit£ degli Studi di Bari"A. Moro" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376383&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 63X 5WBE 4237 160855473 CHEMBL259972 ZINC00003767 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50352070 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 440 ChEMBL 10.1016/j.bmcl.2006.06.036 10.7270/Q2ZS2W33 16814546 Tsai, WJ; Shiao, YJ; Lin, SJ; Chiou, WF; Lin, LC; Yang, TH; Teng, CM; Wu, TS; Yang, LM National Research Institute of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50352073 Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1 InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+ LUKBXSAWLPMMSZ-OWOJBTEDSA-N 23926 (E)-resveratrol::5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol::CHEMBL165::Resveratol::Stilbene, 2f::cid_445154::resveratrol::trans-resveratrol Prostaglandin G/H synthase 2 Ovis aries 3490 ChEMBL 10.1016/j.bmcl.2006.06.036 10.7270/Q2ZS2W33 16814546 Tsai, WJ; Shiao, YJ; Lin, SJ; Chiou, WF; Lin, LC; Yang, TH; Teng, CM; Wu, TS; Yang, LM National Research Institute of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23926&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search STL 6JEM,7WAQ,4QOH,4QOJ,5NZL,1U0W,3MNQ,7K1C,2L98,8ABT,4DPN,2YDX,5CR1,7Q9O,3CKL,1Z1F,1SG0,4PP6,1CGZ,5J54,7CCU,7KD8,4JAZ,1DVS,7CCW,3FTS,5U90,5BTR,4QER,2JIZ,7VB8,4HDA,4Q93 445154 53785926 27881 CHEMBL165 DB02709 C03582 ZINC00006787 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50352076 COc1ccc(cc1OC)\N=N\c1ccc(cc1)S(N)(=O)=O InChI=1S/C14H15N3O4S/c1-20-13-8-5-11(9-14(13)21-2)17-16-10-3-6-12(7-4-10)22(15,18)19/h3-9H,1-2H3,(H2,15,18,19)/b17-16+ BSLAOCJVMOGUKX-WUKNDPDISA-N 50190336 4-((3,4-dimethoxyphenyl)diazenyl)benzenesulfonamide::CHEMBL213326 Prostaglandin G/H synthase 2 Ovis aries 84500 ChEMBL 10.1016/j.bmcl.2006.06.036 10.7270/Q2ZS2W33 16814546 Tsai, WJ; Shiao, YJ; Lin, SJ; Chiou, WF; Lin, LC; Yang, TH; Teng, CM; Wu, TS; Yang, LM National Research Institute of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190336&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 405488 104073649 CHEMBL213326 ZINC06484623 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50352087 CSc1cc(N)ccc1\N=N\c1ccc(cc1)S(N)(=O)=O InChI=1S/C13H14N4O2S2/c1-20-13-8-9(14)2-7-12(13)17-16-10-3-5-11(6-4-10)21(15,18)19/h2-8H,14H2,1H3,(H2,15,18,19)/b17-16+ VKIQIKNZYOSHFW-WUKNDPDISA-N 50140278 4-((E)-4-Amino-2-methylsulfanyl-phenylazo)-benzenesulfonamide::4-(4-amino-2-methylsulfanyl-phenylazo)benzenesulfonamide::CHEMBL17161 Prostaglandin G/H synthase 2 Ovis aries 18000 ChEMBL 10.1016/j.bmcl.2006.06.036 10.7270/Q2ZS2W33 16814546 Tsai, WJ; Shiao, YJ; Lin, SJ; Chiou, WF; Lin, LC; Yang, TH; Teng, CM; Wu, TS; Yang, LM National Research Institute of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140278&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 404198 104029878 CHEMBL17161 ZINC05597162 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50352100 NS(=O)(=O)c1ccc(cc1)N=Nc1ccc(O)c(Cl)c1 InChI=1S/C12H10ClN3O3S/c13-11-7-9(3-6-12(11)17)16-15-8-1-4-10(5-2-8)20(14,18)19/h1-7,17H,(H2,14,18,19) CNOMOEITTQLGJX-UHFFFAOYSA-N 50190335 4-((3-chloro-4-hydroxyphenyl)diazenyl)benzenesulfonamide::CHEMBL215872 Prostaglandin G/H synthase 2 Ovis aries 39700 ChEMBL 10.1016/j.bmcl.2006.06.036 10.7270/Q2ZS2W33 16814546 Tsai, WJ; Shiao, YJ; Lin, SJ; Chiou, WF; Lin, LC; Yang, TH; Teng, CM; Wu, TS; Yang, LM National Research Institute of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190335&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6516154 104073648 CHEMBL215872 ZINC04603519 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50352101 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 340 ChEMBL 10.1016/j.bmcl.2006.06.036 10.7270/Q2ZS2W33 16814546 Tsai, WJ; Shiao, YJ; Lin, SJ; Chiou, WF; Lin, LC; Yang, TH; Teng, CM; Wu, TS; Yang, LM National Research Institute of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50352105 NS(=O)(=O)c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O InChI=1S/C13H11N3O5S/c14-22(20,21)10-4-1-8(2-5-10)15-16-9-3-6-12(17)11(7-9)13(18)19/h1-7,17H,(H,18,19)(H2,14,20,21) NBSRUZQXRUNPNY-UHFFFAOYSA-N 50190337 5-{[4-(aminosulfonyl)phenyl]diazenyl}-2-hydroxybenzoic acid::CHEMBL377353 Prostaglandin G/H synthase 2 Ovis aries 23600 ChEMBL 10.1016/j.bmcl.2006.06.036 10.7270/Q2ZS2W33 16814546 Tsai, WJ; Shiao, YJ; Lin, SJ; Chiou, WF; Lin, LC; Yang, TH; Teng, CM; Wu, TS; Yang, LM National Research Institute of Chinese Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190337&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5351728 104073650 CHEMBL377353 ZINC03953923 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50363832 COc1ccc(cc1)C1=C(COC1=O)c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C18H17NO5S/c1-23-15-9-5-13(6-10-15)17-16(11-24-18(17)20)12-3-7-14(8-4-12)19-25(2,21)22/h3-10,19H,11H2,1-2H3 GUJMAVDSPAQSHW-UHFFFAOYSA-N 50197393 3-(4-methoxyphenyl)-4-(4-methylsulfonamidophenyl)-2(5H)furanone::CHEMBL374170 Prostaglandin G/H synthase 2 Ovis aries 31500 ChEMBL 10.1016/j.bmc.2006.10.023 10.7270/Q2GQ6XD1 17067801 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta Edmonton http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197393&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44422387 104078774 CHEMBL374170 ZINC28640990 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50363833 CS(=O)(=O)Nc1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H15NO4S/c1-23(20,21)18-14-9-7-12(8-10-14)15-11-22-17(19)16(15)13-5-3-2-4-6-13/h2-10,18H,11H2,1H3 SKHGMFMQGDUNDR-UHFFFAOYSA-N 50197394 4-(4-methylsulfonamidophenyl)-3-phenyl-2(5H)furanone::CHEMBL435325 Prostaglandin G/H synthase 2 Ovis aries 1700 ChEMBL 10.1016/j.bmc.2006.10.023 10.7270/Q2GQ6XD1 17067801 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta Edmonton http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197394&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44422372 104078775 CHEMBL435325 ZINC28639931 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50363834 CS(=O)(=O)Nc1ccc(cc1)C1=C(C(=O)OC1)c1ccc(Br)cc1 InChI=1S/C17H14BrNO4S/c1-24(21,22)19-14-8-4-11(5-9-14)15-10-23-17(20)16(15)12-2-6-13(18)7-3-12/h2-9,19H,10H2,1H3 WMMJLFPTJTUTDC-UHFFFAOYSA-N 50197395 3-(4-bromophenyl)-4-(4-methylsulfonamidophenyl)-2(5H)furanone::CHEMBL225476 Prostaglandin G/H synthase 2 Ovis aries 3200 ChEMBL 10.1016/j.bmc.2006.10.023 10.7270/Q2GQ6XD1 17067801 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta Edmonton http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197395&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44422378 104078776 CHEMBL225476 ZINC28640206 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50363837 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmc.2006.10.023 10.7270/Q2GQ6XD1 17067801 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta Edmonton http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50363838 Cc1ccc(cc1)C1=C(COC1=O)c1ccc(NS(C)(=O)=O)cc1 InChI=1S/C18H17NO4S/c1-12-3-5-14(6-4-12)17-16(11-23-18(17)20)13-7-9-15(10-8-13)19-24(2,21)22/h3-10,19H,11H2,1-2H3 RMEOJVZFGHGZJN-UHFFFAOYSA-N 50197396 3-(4-methylphenyl)-4-(4-methylsulfonamidophenyl)-2(5H)furanone::CHEMBL224323 Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.bmc.2006.10.023 10.7270/Q2GQ6XD1 17067801 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta Edmonton http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197396&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 16126757 104078777 CHEMBL224323 ZINC28640988 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50363843 CS(=O)(=O)Nc1ccc(cc1)C1=C(C(=O)OC1)c1ccc(Cl)cc1 InChI=1S/C17H14ClNO4S/c1-24(21,22)19-14-8-4-11(5-9-14)15-10-23-17(20)16(15)12-2-6-13(18)7-3-12/h2-9,19H,10H2,1H3 RGQBWWUZZZBQLU-UHFFFAOYSA-N 50197398 3-(4-chlorophenyl)-4-(4-methylsulfonamidophenyl)-2(5H)furanone::CHEMBL375881 Prostaglandin G/H synthase 2 Ovis aries 800 ChEMBL 10.1016/j.bmc.2006.10.023 10.7270/Q2GQ6XD1 17067801 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta Edmonton http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197398&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44422377 104078779 CHEMBL375881 ZINC28640204 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50363844 CS(=O)(=O)Nc1ccc(cc1)C1=C(C(=O)OC1)c1ccc(F)cc1 InChI=1S/C17H14FNO4S/c1-24(21,22)19-14-8-4-11(5-9-14)15-10-23-17(20)16(15)12-2-6-13(18)7-3-12/h2-9,19H,10H2,1H3 CVOXRVGZXCVEIW-UHFFFAOYSA-N 50197397 3-(4-fluorophenyl)-4-(4-methylsulfonamidophenyl)-2(5H)furanone::CHEMBL224268 Prostaglandin G/H synthase 2 Ovis aries 3200 ChEMBL 10.1016/j.bmc.2006.10.023 10.7270/Q2GQ6XD1 17067801 Zarghi, A; Praveen Rao, PN; Knaus, EE University of Alberta Edmonton http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197397&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44422376 104078778 CHEMBL224268 ZINC28640190 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50364211 CN(c1ccc(N)cc1)S(=O)(=O)c1ccc(Cl)cc1 InChI=1S/C13H13ClN2O2S/c1-16(12-6-4-11(15)5-7-12)19(17,18)13-8-2-10(14)3-9-13/h2-9H,15H2,1H3 GMDIEUYJXFSVPU-UHFFFAOYSA-N 50197704 CHEMBL227544::N-(4-aminophenyl)-4-chloro-N-methylbenzenesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2006.10.029 10.7270/Q2KH0N0X 17079150 Zheng, X; Oda, H; Takamatsu, K; Sugimoto, Y; Tai, A; Akaho, E; Ali, HI; Oshiki, T; Kakuta, H; Sasaki, K Okayama University Graduate School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197704&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 28894546 104078962 CHEMBL227544 ZINC20374281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50364215 CN(c1ccc(N)cc1C)S(=O)(=O)c1ccc(Cl)cc1 InChI=1S/C14H15ClN2O2S/c1-10-9-12(16)5-8-14(10)17(2)20(18,19)13-6-3-11(15)4-7-13/h3-9H,16H2,1-2H3 KQROLVDMBLSYTJ-UHFFFAOYSA-N 50197706 CHEMBL227545::N-(4-amino-2-methylphenyl)-4-chloro-N-methylbenzenesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2006.10.029 10.7270/Q2KH0N0X 17079150 Zheng, X; Oda, H; Takamatsu, K; Sugimoto, Y; Tai, A; Akaho, E; Ali, HI; Oshiki, T; Kakuta, H; Sasaki, K Okayama University Graduate School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197706&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44422670 104078964 CHEMBL227545 ZINC28641954 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50364216 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2006.10.029 10.7270/Q2KH0N0X 17079150 Zheng, X; Oda, H; Takamatsu, K; Sugimoto, Y; Tai, A; Akaho, E; Ali, HI; Oshiki, T; Kakuta, H; Sasaki, K Okayama University Graduate School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50364217 CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccc(N)cc1 InChI=1S/C13H13ClN2O2S/c1-16(12-6-2-10(14)3-7-12)19(17,18)13-8-4-11(15)5-9-13/h2-9H,15H2,1H3 AFQPTMJHMKDDIB-UHFFFAOYSA-N 50197708 4-amino-N-(4-chlorophenyl)-N-methylbenzenesulfonamide::CHEMBL227980 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2006.10.029 10.7270/Q2KH0N0X 17079150 Zheng, X; Oda, H; Takamatsu, K; Sugimoto, Y; Tai, A; Akaho, E; Ali, HI; Oshiki, T; Kakuta, H; Sasaki, K Okayama University Graduate School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197708&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 16126699 104078966 CHEMBL227980 ZINC11757504 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50364220 Nc1ccc(cc1)S(=O)(=O)Nc1ccc(Cl)cc1 InChI=1S/C12H11ClN2O2S/c13-9-1-5-11(6-2-9)15-18(16,17)12-7-3-10(14)4-8-12/h1-8,15H,14H2 RBJGYDGKXTYSSL-UHFFFAOYSA-N 50197705 4-amino-N-(4-chlorophenyl)benzenesulfonamide::CHEMBL227413 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2006.10.029 10.7270/Q2KH0N0X 17079150 Zheng, X; Oda, H; Takamatsu, K; Sugimoto, Y; Tai, A; Akaho, E; Ali, HI; Oshiki, T; Kakuta, H; Sasaki, K Okayama University Graduate School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197705&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 788021 104078963 CHEMBL227413 ZINC00286765 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50364223 COc1cc(N)ccc1N(C)S(=O)(=O)c1ccc(Cl)cc1 InChI=1S/C14H15ClN2O3S/c1-17(13-8-5-11(16)9-14(13)20-2)21(18,19)12-6-3-10(15)4-7-12/h3-9H,16H2,1-2H3 UXLJIKBAHMTBAC-UHFFFAOYSA-N 50197707 CHEMBL389184::N-(4-amino-2-methoxyphenyl)-4-chloro-N-methylbenzenesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2006.10.029 10.7270/Q2KH0N0X 17079150 Zheng, X; Oda, H; Takamatsu, K; Sugimoto, Y; Tai, A; Akaho, E; Ali, HI; Oshiki, T; Kakuta, H; Sasaki, K Okayama University Graduate School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197707&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44422676 104078965 CHEMBL389184 ZINC28642314 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50364224 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 7700 ChEMBL 10.1016/j.bmc.2006.10.029 10.7270/Q2KH0N0X 17079150 Zheng, X; Oda, H; Takamatsu, K; Sugimoto, Y; Tai, A; Akaho, E; Ali, HI; Oshiki, T; Kakuta, H; Sasaki, K Okayama University Graduate School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50386633 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmc.2007.05.009 10.7270/Q23B5ZT7 17509888 Velazquez, CA; Praveen Rao, PN; Citro, ML; Keefer, LK; Knaus, EE National Cancer Institute at Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50386634 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCCN(C)[N+](\[O-])=N\OCOC(C)=O)c2c1 InChI=1S/C25H27ClN4O8/c1-16-21(14-24(32)36-12-11-28(3)30(34)27-38-15-37-17(2)31)22-13-20(35-4)9-10-23(22)29(16)25(33)18-5-7-19(26)8-6-18/h5-10,13H,11-12,14-15H2,1-4H3/b30-27- LYMCMAZLKXOIDD-IKPAITLHSA-N 50213229 CHEMBL229738::O2-acetoxymethyl 1-{N-[2-(2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetoxy)ethyl]-N-methylamino}diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2007.05.009 10.7270/Q23B5ZT7 17509888 Velazquez, CA; Praveen Rao, PN; Citro, ML; Keefer, LK; Knaus, EE National Cancer Institute at Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213229&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44424059 104088714 CHEMBL229738 ZINC28649113 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50386638 CN(CCOC(=O)c1ccccc1OC(C)=O)[N+](\[O-])=N\OCOC(C)=O InChI=1S/C15H19N3O8/c1-11(19)24-10-25-16-18(22)17(3)8-9-23-15(21)13-6-4-5-7-14(13)26-12(2)20/h4-7H,8-10H2,1-3H3/b18-16- UHPWNFBIXMRFMH-VLGSPTGOSA-N 50213231 CHEMBL387966::O2-acetoxymethyl 1-[N-(2-(acetylsalicyloyloxy)ethyl)-N-methylamino]diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2007.05.009 10.7270/Q23B5ZT7 17509888 Velazquez, CA; Praveen Rao, PN; Citro, ML; Keefer, LK; Knaus, EE National Cancer Institute at Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213231&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44424057 104088716 CHEMBL387966 ZINC28649090 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50386640 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 5700 ChEMBL 10.1016/j.bmc.2007.05.009 10.7270/Q23B5ZT7 17509888 Velazquez, CA; Praveen Rao, PN; Citro, ML; Keefer, LK; Knaus, EE National Cancer Institute at Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50386641 CC(C)Cc1ccc(cc1)C(C)C(=O)OCCN(C)[N+](\[O-])=N\OCOC(C)=O InChI=1S/C19H29N3O6/c1-14(2)12-17-6-8-18(9-7-17)15(3)19(24)26-11-10-21(5)22(25)20-28-13-27-16(4)23/h6-9,14-15H,10-13H2,1-5H3/b22-20- SEIAPNZQAXURTQ-XDOYNYLZSA-N 50213230 CHEMBL229737::O2-acetoxymethyl 1-{N-[2-(2-[4-(isobutyl)phenyl]propanoyloxy)ethyl]-N-methylamino}diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2007.05.009 10.7270/Q23B5ZT7 17509888 Velazquez, CA; Praveen Rao, PN; Citro, ML; Keefer, LK; Knaus, EE National Cancer Institute at Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213230&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44424058 104088715 CHEMBL229737 ZINC28649109 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50386643 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1016/j.bmc.2007.05.009 10.7270/Q23B5ZT7 17509888 Velazquez, CA; Praveen Rao, PN; Citro, ML; Keefer, LK; Knaus, EE National Cancer Institute at Frederick http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50410191 CS(=O)(=O)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 InChI=1S/C14H13FN2O3S/c1-21(19,20)13-8-6-12(7-9-13)17-14(18)16-11-4-2-10(15)3-5-11/h2-9H,1H3,(H2,16,17,18) WSZNZRIPAHACAK-UHFFFAOYSA-N 50233178 1-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)urea::CHEMBL252630 Prostaglandin G/H synthase 2 Ovis aries 130 ChEMBL 10.1016/j.bmcl.2008.01.021 10.7270/Q2Z89C4T 18226898 Zarghi, A; Kakhgi, S; Hadipoor, A; Daraee, B; Dadrass, OG; Hedayati, M Shaheed Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233178&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44447100 104055680 CHEMBL252630 ZINC29038900 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50410192 CS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 InChI=1S/C14H13ClN2O3S/c1-21(19,20)13-8-6-12(7-9-13)17-14(18)16-11-4-2-10(15)3-5-11/h2-9H,1H3,(H2,16,17,18) CVTIFAOVBHXURR-UHFFFAOYSA-N 50233179 1-(4-chlorophenyl)-3-(4-(methylsulfonyl)phenyl)urea::CHEMBL253195 Prostaglandin G/H synthase 2 Ovis aries 270 ChEMBL 10.1016/j.bmcl.2008.01.021 10.7270/Q2Z89C4T 18226898 Zarghi, A; Kakhgi, S; Hadipoor, A; Daraee, B; Dadrass, OG; Hedayati, M Shaheed Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233179&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44447101 104055681 CHEMBL253195 ZINC29038902 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50410193 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmcl.2008.01.021 10.7270/Q2Z89C4T 18226898 Zarghi, A; Kakhgi, S; Hadipoor, A; Daraee, B; Dadrass, OG; Hedayati, M Shaheed Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50410194 COc1ccc(NC(=O)Nc2ccc(cc2)S(C)(=O)=O)cc1 InChI=1S/C15H16N2O4S/c1-21-13-7-3-11(4-8-13)16-15(18)17-12-5-9-14(10-6-12)22(2,19)20/h3-10H,1-2H3,(H2,16,17,18) FAHTUCLYYDEVNW-UHFFFAOYSA-N 50233180 1-(4-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl)urea::CHEMBL254465 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.bmcl.2008.01.021 10.7270/Q2Z89C4T 18226898 Zarghi, A; Kakhgi, S; Hadipoor, A; Daraee, B; Dadrass, OG; Hedayati, M Shaheed Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233180&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 25110789 104055682 CHEMBL254465 ZINC29038909 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50410198 Cc1ccc(NC(=O)Nc2ccc(cc2)S(C)(=O)=O)cc1 InChI=1S/C15H16N2O3S/c1-11-3-5-12(6-4-11)16-15(18)17-13-7-9-14(10-8-13)21(2,19)20/h3-10H,1-2H3,(H2,16,17,18) ZWDYDUJTBVZZLR-UHFFFAOYSA-N 50233181 1-(4-(methylsulfonyl)phenyl)-3-p-tolylurea::CHEMBL253402 Prostaglandin G/H synthase 2 Ovis aries 330 ChEMBL 10.1016/j.bmcl.2008.01.021 10.7270/Q2Z89C4T 18226898 Zarghi, A; Kakhgi, S; Hadipoor, A; Daraee, B; Dadrass, OG; Hedayati, M Shaheed Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233181&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44447102 104055683 CHEMBL253402 ZINC29038906 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50410201 CS(=O)(=O)c1ccc(NC(=O)Nc2ccccc2)cc1 InChI=1S/C14H14N2O3S/c1-20(18,19)13-9-7-12(8-10-13)16-14(17)15-11-5-3-2-4-6-11/h2-10H,1H3,(H2,15,16,17) BNCVKEKVEUVIPN-UHFFFAOYSA-N 50233182 1-(4-(methylsulfonyl)phenyl)-3-phenylurea::CHEMBL252433 Prostaglandin G/H synthase 2 Ovis aries 170 ChEMBL 10.1016/j.bmcl.2008.01.021 10.7270/Q2Z89C4T 18226898 Zarghi, A; Kakhgi, S; Hadipoor, A; Daraee, B; Dadrass, OG; Hedayati, M Shaheed Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50233182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50233182&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44447099 104055684 CHEMBL252433 ZINC29038894 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397479 CCN(CC)N([O-])N=[O+]COC(=O)C(=Cc1ccc(cc1)S(C)(=O)=O)c1ccc(F)cc1 InChI=1S/C21H24FN3O6S/c1-4-24(5-2)25(27)23-31-15-30-21(26)20(17-8-10-18(22)11-9-17)14-16-6-12-19(13-7-16)32(3,28)29/h6-14H,4-5,15H2,1-3H3 HLEKIAUAAMFAOC-UHFFFAOYSA-N 50220443 CHEMBL239645::O2-[(E)-2-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)acryloyloxymethyl]-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries 2300 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220443&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44437287 104093424 CHEMBL239645 ZINC28872670 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397480 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397482 CCN(CC)N([O-])N=[O+]COC(=O)C(=Cc1ccc(cc1)S(C)(=O)=O)c1cccc(Br)c1 InChI=1S/C21H24BrN3O6S/c1-4-24(5-2)25(27)23-31-15-30-21(26)20(17-7-6-8-18(22)14-17)13-16-9-11-19(12-10-16)32(3,28)29/h6-14H,4-5,15H2,1-3H3 DKOLCOGGISRIGU-UHFFFAOYSA-N 50220445 CHEMBL239429::O2-[(E)-2-(3-bromophenyl)-3-(4-methanesulfonylphenyl)acryloyloxymethyl]-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries 31600 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220445&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44437280 104093426 CHEMBL239429 ZINC28872657 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397483 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397484 CCN(CC)N([O-])N=[O+]COC(=O)C(=Cc1ccc(cc1)S(C)(=O)=O)c1ccc(NC(C)=O)cc1 InChI=1S/C23H28N4O7S/c1-5-26(6-2)27(30)25-34-16-33-23(29)22(19-9-11-20(12-10-19)24-17(3)28)15-18-7-13-21(14-8-18)35(4,31)32/h7-15H,5-6,16H2,1-4H3,(H,24,28) MHLNDNNSSPWCSE-UHFFFAOYSA-N 50220444 CHEMBL240076::O2-[(E)-2-(4-acetylaminophenyl)-3-(4-methanesulfonylphenyl)acryloyloxymethyl]-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries 16800 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220444&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44437292 104093425 CHEMBL240076 ZINC28872707 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397489 CS(=O)(=O)c1ccc(C=C(C(=O)OC[O+]=NN([O-])N2CCCC2)c2cccc(Br)c2)cc1 InChI=1S/C21H22BrN3O6S/c1-32(28,29)19-9-7-16(8-10-19)13-20(17-5-4-6-18(22)14-17)21(26)30-15-31-23-25(27)24-11-2-3-12-24/h4-10,13-14H,2-3,11-12,15H2,1H3 BPVOZSFVINSYLA-UHFFFAOYSA-N 50220447 CHEMBL239642::O2-[(E)-2-(3-bromophenyl)-3-(4-methanesulfonylphenyl)acryloyloxymethyl]-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries 11500 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220447&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44437281 104093428 CHEMBL239642 ZINC28872661 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397492 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397493 CS(=O)(=O)c1ccc(C=C(C(=O)OC[O+]=NN([O-])N2CCCC2)c2ccc(F)cc2)cc1 InChI=1S/C21H22FN3O6S/c1-32(28,29)19-10-4-16(5-11-19)14-20(17-6-8-18(22)9-7-17)21(26)30-15-31-23-25(27)24-12-2-3-13-24/h4-11,14H,2-3,12-13,15H2,1H3 WURCEDKMKPUVCU-UHFFFAOYSA-N 50220448 CHEMBL239860::O2-[(E)-2-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)acryloyloxymethyl]-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries 10800 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220448&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44437288 104093429 CHEMBL239860 ZINC28872672 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50397495 CC(=O)Nc1ccc(cc1)C(=Cc1ccc(cc1)S(C)(=O)=O)C(=O)OC[O+]=NN([O-])N1CCCC1 InChI=1S/C23H26N4O7S/c1-17(28)24-20-9-7-19(8-10-20)22(15-18-5-11-21(12-6-18)35(2,31)32)23(29)33-16-34-25-27(30)26-13-3-4-14-26/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,24,28) RROONBYRBMMETK-UHFFFAOYSA-N 50220446 CHEMBL392114::O2-[(E)-2-(4-acetylaminophenyl)-3-(4-methanesulfonylphenyl)acryloyloxymethyl]-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries 940 ChEMBL 10.1016/j.bmc.2007.07.021 10.7270/Q28052B9 17764958 Abdellatif, KR; Dong, Y; Chen, QH; Chowdhury, MA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50220446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50220446&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44437293 104093427 CHEMBL392114 ZINC28872712 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50404210 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 40 ChEMBL 10.1016/j.bmc.2007.09.038 10.7270/Q22N520H 17937989 Gadad, AK; Palkar, MB; Anand, K; Noolvi, MN; Boreddy, TS; Wagwade, J The University of the West Indies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50404211 COc1ccc(cc1)-c1c(nc2sc(nn12)S(N)(=O)=O)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C18H16N4O5S3/c1-27-13-7-3-12(4-8-13)16-15(11-5-9-14(10-6-11)29(2,23)24)20-17-22(16)21-18(28-17)30(19,25)26/h3-10H,1-2H3,(H2,19,25,26) PEKDVBCRYQOVTK-UHFFFAOYSA-N 50225131 2-sulfonamido-5-(4'-methoxyphenyl)-6-(4''-(methylsulfonyl)phenyl)imidazo[2,1-b]-1,3,4-thiadiazole::CHEMBL404424 Prostaglandin G/H synthase 2 Ovis aries 3240 ChEMBL 10.1016/j.bmc.2007.09.038 10.7270/Q22N520H 17937989 Gadad, AK; Palkar, MB; Anand, K; Noolvi, MN; Boreddy, TS; Wagwade, J The University of the West Indies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225131&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44445947 104096606 CHEMBL404424 ZINC28975684 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50404214 CS(=O)(=O)c1ccc(cc1)-c1nc2sc(nn2c1-c1ccccc1)C(F)(F)F InChI=1S/C18H12F3N3O2S2/c1-28(25,26)13-9-7-11(8-10-13)14-15(12-5-3-2-4-6-12)24-17(22-14)27-16(23-24)18(19,20)21/h2-10H,1H3 YBKLASQHGUPEDZ-UHFFFAOYSA-N 50225132 2-trifluoromethyl-5-phenyl-6-(4''-(methylsulfonyl)-phenyl)imidazo[2,1-b]-1,3,4-thiadiazole::CHEMBL253725 Prostaglandin G/H synthase 2 Ovis aries 4790 ChEMBL 10.1016/j.bmc.2007.09.038 10.7270/Q22N520H 17937989 Gadad, AK; Palkar, MB; Anand, K; Noolvi, MN; Boreddy, TS; Wagwade, J The University of the West Indies http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225132&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 24882330 104096607 CHEMBL253725 ZINC28975711 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401225 Oc1ccc(-c2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)c(O)c1 InChI=1S/C24H17N5O4/c30-17-11-12-18(19(31)13-17)23-27-26-20(33-23)14-29-24(32)25-21(15-7-3-1-4-8-15)22(28-29)16-9-5-2-6-10-16/h1-13,30-31H,14H2 WVNWXGUPFZZHDX-UHFFFAOYSA-N 50114413 CHEMBL3608346 Prostaglandin G/H synthase 2 Ovis aries 3070 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114413&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186821 104008489 CHEMBL3608346 ZINC00022966 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401226 Nc1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C24H18N6O2/c25-19-13-11-18(12-14-19)23-28-27-20(32-23)15-30-24(31)26-21(16-7-3-1-4-8-16)22(29-30)17-9-5-2-6-10-17/h1-14H,15,25H2 NXUGNUNUQPRQIH-UHFFFAOYSA-N 50114414 CHEMBL3608347 Prostaglandin G/H synthase 2 Ovis aries 3100 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114414&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186822 104008490 CHEMBL3608347 ZINC13442817 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401227 Clc1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C24H16ClN5O2/c25-19-13-11-18(12-14-19)23-28-27-20(32-23)15-30-24(31)26-21(16-7-3-1-4-8-16)22(29-30)17-9-5-2-6-10-17/h1-14H,15H2 QUBLCFFIKVKFME-UHFFFAOYSA-N 50114415 CHEMBL3608348 Prostaglandin G/H synthase 2 Ovis aries 3130 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114415&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10813067 104008491 CHEMBL3608348 ZINC13442827 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401228 COc1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C25H19N5O3/c1-32-20-14-12-19(13-15-20)24-28-27-21(33-24)16-30-25(31)26-22(17-8-4-2-5-9-17)23(29-30)18-10-6-3-7-11-18/h2-15H,16H2,1H3 BLDMCAJCUTWQRV-UHFFFAOYSA-N 50114416 CHEMBL3608351 Prostaglandin G/H synthase 2 Ovis aries 3230 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114416&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186826 104008492 CHEMBL3608351 ZINC00007607 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401229 [O-][N+](=O)c1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C24H16N6O4/c31-24-25-21(16-7-3-1-4-8-16)22(17-9-5-2-6-10-17)28-29(24)15-20-26-27-23(34-20)18-11-13-19(14-12-18)30(32)33/h1-14H,15H2 LCPYSDJBXZLZLO-UHFFFAOYSA-N 50114417 CHEMBL3608353 Prostaglandin G/H synthase 2 Ovis aries 3160 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114417&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186828 104008493 CHEMBL3608353 ZINC13442839 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401230 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 3930 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401231 Oc1ccc(-c2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)c(O)c1 InChI=1S/C24H17N5O4/c30-17-11-12-18(19(31)13-17)23-27-26-20(33-23)14-29-24(32)25-21(15-7-3-1-4-8-15)22(28-29)16-9-5-2-6-10-16/h1-13,30-31H,14H2 WVNWXGUPFZZHDX-UHFFFAOYSA-N 50114413 CHEMBL3608346 Prostaglandin G/H synthase 2 Ovis aries 14510 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114413&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186821 104008489 CHEMBL3608346 ZINC00022966 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401232 Nc1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C24H18N6O2/c25-19-13-11-18(12-14-19)23-28-27-20(32-23)15-30-24(31)26-21(16-7-3-1-4-8-16)22(29-30)17-9-5-2-6-10-17/h1-14H,15,25H2 NXUGNUNUQPRQIH-UHFFFAOYSA-N 50114414 CHEMBL3608347 Prostaglandin G/H synthase 2 Ovis aries 14620 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114414&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186822 104008490 CHEMBL3608347 ZINC13442817 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401233 Clc1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C24H16ClN5O2/c25-19-13-11-18(12-14-19)23-28-27-20(32-23)15-30-24(31)26-21(16-7-3-1-4-8-16)22(29-30)17-9-5-2-6-10-17/h1-14H,15H2 QUBLCFFIKVKFME-UHFFFAOYSA-N 50114415 CHEMBL3608348 Prostaglandin G/H synthase 2 Ovis aries 14710 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114415&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10813067 104008491 CHEMBL3608348 ZINC13442827 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401234 COc1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C25H19N5O3/c1-32-20-14-12-19(13-15-20)24-28-27-21(33-24)16-30-25(31)26-22(17-8-4-2-5-9-17)23(29-30)18-10-6-3-7-11-18/h2-15H,16H2,1H3 BLDMCAJCUTWQRV-UHFFFAOYSA-N 50114416 CHEMBL3608351 Prostaglandin G/H synthase 2 Ovis aries 14750 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114416&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186826 104008492 CHEMBL3608351 ZINC00007607 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401235 [O-][N+](=O)c1ccc(cc1)-c1nnc(Cn2nc(-c3ccccc3)c(nc2=O)-c2ccccc2)o1 InChI=1S/C24H16N6O4/c31-24-25-21(16-7-3-1-4-8-16)22(17-9-5-2-6-10-17)28-29(24)15-20-26-27-23(34-20)18-11-13-19(14-12-18)30(32)33/h1-14H,15H2 LCPYSDJBXZLZLO-UHFFFAOYSA-N 50114417 CHEMBL3608353 Prostaglandin G/H synthase 2 Ovis aries 14790 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50114417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50114417&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122186828 104008493 CHEMBL3608353 ZINC13442839 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50401236 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 9860 ChEMBL 10.1016/j.ejmech.2015.06.020 10.7270/Q2J38VCX 26117820 Banerjee, AG; Das, N; Shengule, SA; Srivastava, RS; Shrivastava, SK Indian Institute of Technology (Banaras Hindu University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50405660 CC1=CC(NC(=S)N1)c1ccccc1[N+]([O-])=O InChI=1S/C11H11N3O2S/c1-7-6-9(13-11(17)12-7)8-4-2-3-5-10(8)14(15)16/h2-6,9H,1H3,(H2,12,13,17) XWBDLWZCHDMKEW-UHFFFAOYSA-N 50116888 CHEMBL3612976 Prostaglandin G/H synthase 2 Ovis aries 50000 ChEMBL 10.1016/j.ejmech.2015.07.003 10.7270/Q20003XZ 26197159 Seebacher, W; Faist, J; Presser, A; Weis, R; Saf, R; Kaserer, T; Temml, V; Schuster, D; Ortmann, S; Otto, N; Bauer, R University of Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116888&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122188615 104010514 CHEMBL3612976 ZINC26487707 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50407776 Cc1ccc(cc1)S(=O)(=O)n1cc(c2ccccc12)[C@@]1(O)C[C@H](CI)OC1=O InChI=1S/C20H18INO5S/c1-13-6-8-15(9-7-13)28(25,26)22-12-17(16-4-2-3-5-18(16)22)20(24)10-14(11-21)27-19(20)23/h2-9,12,14,24H,10-11H2,1H3/t14-,20+/m1/s1 YALVAXXGZAEUBN-VLIAUNLRSA-N 50229317 (3S,5R)-3-hydroxy-5-(iodomethyl)-3-(1-tosyl-1H-indol-3-yl)-dihydrofuran-2(3H)-one::CHEMBL252444 Prostaglandin G/H synthase 2 Ovis aries >10000 ChEMBL 10.1016/j.bmcl.2007.11.010 10.7270/Q21C1WNC 18061444 Singh, P; Mittal, A; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50229317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50229317&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44446901 104098126 CHEMBL252444 ZINC29038261 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50407778 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.bmcl.2007.11.010 10.7270/Q21C1WNC 18061444 Singh, P; Mittal, A; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50407780 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 750 ChEMBL 10.1016/j.bmcl.2007.11.010 10.7270/Q21C1WNC 18061444 Singh, P; Mittal, A; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50431044 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 560 ChEMBL 10.1016/j.bmc.2015.10.007 10.7270/Q22N543P 26455657 Yamamoto, Y; Hisa, T; Arai, J; Saito, Y; Yamamoto, F; Mukai, T; Ohshima, T; Maeda, M; Ohkubo, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50431045 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 11800 ChEMBL 10.1016/j.bmc.2015.10.007 10.7270/Q22N543P 26455657 Yamamoto, Y; Hisa, T; Arai, J; Saito, Y; Yamamoto, F; Mukai, T; Ohshima, T; Maeda, M; Ohkubo, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50431046 COc1ccc(Oc2cc(ccc2NS(C)(=O)=O)[N+]([O-])=O)cc1 InChI=1S/C14H14N2O6S/c1-21-11-4-6-12(7-5-11)22-14-9-10(16(17)18)3-8-13(14)15-23(2,19)20/h3-9,15H,1-2H3 OBTVYILXIRNVAP-UHFFFAOYSA-N 50128688 CHEMBL3628727 Prostaglandin G/H synthase 2 Ovis aries 2310 ChEMBL 10.1016/j.bmc.2015.10.007 10.7270/Q22N543P 26455657 Yamamoto, Y; Hisa, T; Arai, J; Saito, Y; Yamamoto, F; Mukai, T; Ohshima, T; Maeda, M; Ohkubo, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128688&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9884264 104020451 CHEMBL3628727 ZINC36268676 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50431047 COc1cccc(Oc2cc(ccc2NS(C)(=O)=O)[N+]([O-])=O)c1 InChI=1S/C14H14N2O6S/c1-21-11-4-3-5-12(9-11)22-14-8-10(16(17)18)6-7-13(14)15-23(2,19)20/h3-9,15H,1-2H3 MNCWVCGDSFWTPZ-UHFFFAOYSA-N 50128691 CHEMBL3628630 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2015.10.007 10.7270/Q22N543P 26455657 Yamamoto, Y; Hisa, T; Arai, J; Saito, Y; Yamamoto, F; Mukai, T; Ohshima, T; Maeda, M; Ohkubo, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128691&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122193636 104020454 CHEMBL3628630 ZINC36268663 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50431048 COc1ccccc1Oc1cc(ccc1NS(C)(=O)=O)[N+]([O-])=O InChI=1S/C14H14N2O6S/c1-21-12-5-3-4-6-13(12)22-14-9-10(16(17)18)7-8-11(14)15-23(2,19)20/h3-9,15H,1-2H3 CLLIMIGBXYECCK-UHFFFAOYSA-N 50128748 CHEMBL3628629 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2015.10.007 10.7270/Q22N543P 26455657 Yamamoto, Y; Hisa, T; Arai, J; Saito, Y; Yamamoto, F; Mukai, T; Ohshima, T; Maeda, M; Ohkubo, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128748&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122193635 321902705 CHEMBL3628629 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50431049 CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1)[N+]([O-])=O InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3 HYWYRSMBCFDLJT-UHFFFAOYSA-N 50056999 CHEMBL56367::nimesulide Prostaglandin G/H synthase 2 Ovis aries 1920 ChEMBL 10.1016/j.bmc.2015.10.007 10.7270/Q22N543P 26455657 Yamamoto, Y; Hisa, T; Arai, J; Saito, Y; Yamamoto, F; Mukai, T; Ohshima, T; Maeda, M; Ohkubo, Y Tohoku Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056999&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NIM 1ZWP,3N8X,3E9X,2OTH,4EIX 4495 103953101 44445 CHEMBL56367 DB04743 ZINC04617749 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50444561 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 537 ChEMBL 10.1016/j.ejmech.2008.10.039 10.7270/Q27P8Z7F 19084295 Dundar, Y; Unlu, S; Banoqlu, E; Entrena, A; Costantino, G; Nunez, MT; Ledo, F; Sahin, MF; Noyanalpan, N Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50444563 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 398 ChEMBL 10.1016/j.ejmech.2008.10.039 10.7270/Q27P8Z7F 19084295 Dundar, Y; Unlu, S; Banoqlu, E; Entrena, A; Costantino, G; Nunez, MT; Ledo, F; Sahin, MF; Noyanalpan, N Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50444565 Cn1c(c(oc1=O)-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 InChI=1S/C16H14N2O4S/c1-18-14(11-5-3-2-4-6-11)15(22-16(18)19)12-7-9-13(10-8-12)23(17,20)21/h2-10H,1H3,(H2,17,20,21) UUQDSPWZJMNRIR-UHFFFAOYSA-N 50279625 4-(4-Phenyl-3-methyl-2-oxo-3H-1,3-oxazol-5-yl)benzensulfonamide::CHEMBL484814 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/j.ejmech.2008.10.039 10.7270/Q27P8Z7F 19084295 Dundar, Y; Unlu, S; Banoqlu, E; Entrena, A; Costantino, G; Nunez, MT; Ledo, F; Sahin, MF; Noyanalpan, N Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279625&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42632610 104121418 CHEMBL484814 ZINC40938752 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436479 NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(CO)cc1)C(F)(F)F InChI=1S/C17H14F3N3O3S/c18-17(19,20)16-9-15(12-3-1-11(10-24)2-4-12)23(22-16)13-5-7-14(8-6-13)27(21,25)26/h1-9,24H,10H2,(H2,21,25,26) ICRSYPPLGADZKA-UHFFFAOYSA-N 50057538 4-[5-(4-Hydroxymethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::4-[5-(4-Hydroxymethylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide::CHEMBL745::Primary alcohol metabolite of celecoxib Prostaglandin G/H synthase 2 Ovis aries 3700 ChEMBL 10.1016/j.bmc.2008.10.001 10.7270/Q2PN95HK 18930406 Abdellatif, KR; Chowdhury, MA; Dong, Y; Velazquez, C; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057538&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9908776 103953590 CHEMBL745 ZINC13761818 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436480 CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(CO)cc1)C(F)(F)F InChI=1S/C18H15F3N2O3S/c1-27(25,26)15-8-6-14(7-9-15)23-16(10-17(22-23)18(19,20)21)13-4-2-12(11-24)3-5-13/h2-10,24H,11H2,1H3 PZGLSVDHBUNPKY-UHFFFAOYSA-N 50275666 5-(4-Hydroxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole::CHEMBL486763 Prostaglandin G/H synthase 2 Ovis aries 10500 ChEMBL 10.1016/j.bmc.2008.10.001 10.7270/Q2PN95HK 18930406 Abdellatif, KR; Chowdhury, MA; Dong, Y; Velazquez, C; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275666&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44589773 104119073 CHEMBL486763 ZINC40421477 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436481 CC(=O)OCO\N=[N+](/[O-])N1CCC[C@H]1C(=O)OCc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C25H25F3N6O8S/c1-16(35)41-15-42-31-34(37)32-12-2-3-21(32)24(36)40-14-17-4-6-18(7-5-17)22-13-23(25(26,27)28)30-33(22)19-8-10-20(11-9-19)43(29,38)39/h4-11,13,21H,2-3,12,14-15H2,1H3,(H2,29,38,39)/b34-31-/t21-/m0/s1 WICOHTJHTHQKDJ-HKMMODACSA-N 50275667 CHEMBL500062::O2-Acetoxymethyl 1-{2-[4-(1-(4-sulfamoylphenyl)-3-trifluoromethyl-1H-pyrazol-5-yl)phenylmethoxycarbonyl]pyrrolidin-1-yl}diazen-1-ium-1,2-diolate Prostaglandin G/H synthase 2 Ovis aries 4900 ChEMBL 10.1016/j.bmc.2008.10.001 10.7270/Q2PN95HK 18930406 Abdellatif, KR; Chowdhury, MA; Dong, Y; Velazquez, C; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275667&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 25147654 104119074 CHEMBL500062 ZINC49889161 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436482 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2008.10.001 10.7270/Q2PN95HK 18930406 Abdellatif, KR; Chowdhury, MA; Dong, Y; Velazquez, C; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436483 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmc.2008.10.001 10.7270/Q2PN95HK 18930406 Abdellatif, KR; Chowdhury, MA; Dong, Y; Velazquez, C; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436484 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1016/j.bmc.2008.10.001 10.7270/Q2PN95HK 18930406 Abdellatif, KR; Chowdhury, MA; Dong, Y; Velazquez, C; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436716 CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccn(O)c(=O)c1)C(F)(F)F InChI=1S/C16H12F3N3O4S/c1-27(25,26)12-4-2-11(3-5-12)22-13(9-14(20-22)16(17,18)19)10-6-7-21(24)15(23)8-10/h2-9,24H,1H3 OJRVGYNHAYPHOR-UHFFFAOYSA-N 50246473 1-(4-Methylsulfonylphenyl)-3-trifluoromethyl-5-[4-(1-hydroxy-1,2-dihydropyrid-2-one]-1H-pyrazole::1-hydroxy-4-(1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-2(1H)-one::CHEMBL452605 Prostaglandin G/H synthase 2 Ovis aries 7500 ChEMBL 10.1016/j.bmcl.2008.10.009 10.7270/Q2SF2W16 18945614 Chowdhury, MA; Abdellatif, KR; Dong, Y; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246473&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 25168718 104101896 CHEMBL452605 ZINC53282806 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436720 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmcl.2008.10.009 10.7270/Q2SF2W16 18945614 Chowdhury, MA; Abdellatif, KR; Dong, Y; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436721 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmcl.2008.10.009 10.7270/Q2SF2W16 18945614 Chowdhury, MA; Abdellatif, KR; Dong, Y; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50436722 NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccn(O)c(=O)c1)C(F)(F)F InChI=1S/C15H11F3N4O4S/c16-15(17,18)13-8-12(9-5-6-21(24)14(23)7-9)22(20-13)10-1-3-11(4-2-10)27(19,25)26/h1-8,24H,(H2,19,25,26) PJJGQOOKFTZAPT-UHFFFAOYSA-N 50246522 1-(4-Aminosulfonylphenyl)-3-trifluoromethyl-5-[4-(1-hydroxy-1,2-dihydropyrid-2-one]-1H-pyrazole::4-(5-(1-hydroxy-2-oxo-1,2-dihydropyridin-4-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide::CHEMBL462224 Prostaglandin G/H synthase 2 Ovis aries 7500 ChEMBL 10.1016/j.bmcl.2008.10.009 10.7270/Q2SF2W16 18945614 Chowdhury, MA; Abdellatif, KR; Dong, Y; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246522&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 25168853 104101929 CHEMBL462224 ZINC53277608 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50447630 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1016/j.bmcl.2008.12.066 10.7270/Q22R3RJ7 19136259 Chowdhury, MA; Abdellatif, KR; Dong, Y; Rahman, M; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50447631 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmcl.2008.12.066 10.7270/Q22R3RJ7 19136259 Chowdhury, MA; Abdellatif, KR; Dong, Y; Rahman, M; Das, D; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50435877 CCSC[C@@H]1C[C@](C)(O)C[C@@H](O1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C15H21NO4S/c1-3-21-10-13-8-15(2,17)9-14(20-13)11-4-6-12(7-5-11)16(18)19/h4-7,13-14,17H,3,8-10H2,1-2H3/t13-,14+,15-/m0/s1 MPTDFBGZBJDDLK-ZNMIVQPWSA-N 50249340 (2S,4R,6R)-2-(ethylthiomethyl)-4-methyl-6-(4-nitrophenyl)tetrahydro-2H-pyran-4-ol::CHEMBL475582 Prostaglandin G/H synthase 2 Ovis aries >10000 ChEMBL 10.1016/j.ejmech.2008.08.008 10.7270/Q2H41R8Q 18835505 Singh, P; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249340&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42599214 104103662 CHEMBL475582 ZINC40898791 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50435878 C[C@]1(O)C[C@@H](CSC#N)O[C@H](C1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C14H16N2O4S/c1-14(17)6-12(8-21-9-15)20-13(7-14)10-2-4-11(5-3-10)16(18)19/h2-5,12-13,17H,6-8H2,1H3/t12-,13+,14-/m0/s1 AININMBFVYBCEE-MJBXVCDLSA-N 50249341 (2R,4R,6S)-4-methyl-2-(4-nitrophenyl)-6-(thiocyanatomethyl)tetrahydro-2H-pyran-4-ol::CHEMBL475583 Prostaglandin G/H synthase 2 Ovis aries >10000 ChEMBL 10.1016/j.ejmech.2008.08.008 10.7270/Q2H41R8Q 18835505 Singh, P; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249341&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42599215 104103663 CHEMBL475583 ZINC40899275 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50435880 C[C@]1(O)C[C@@H](CSC#N)O[C@H](C1)c1ccc(F)cc1 InChI=1S/C14H16FNO2S/c1-14(17)6-12(8-19-9-16)18-13(7-14)10-2-4-11(15)5-3-10/h2-5,12-13,17H,6-8H2,1H3/t12-,13+,14-/m0/s1 HWEZADQPZOJSED-MJBXVCDLSA-N 50249343 (2R,4R,6S)-2-(4-fluorophenyl)-4-methyl-6-(thiocyanatomethyl)tetrahydro-2H-pyran-4-ol::CHEMBL475350 Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.1016/j.ejmech.2008.08.008 10.7270/Q2H41R8Q 18835505 Singh, P; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249343&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42599216 104103665 CHEMBL475350 ZINC40899136 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50435881 CCSC[C@@H]1C[C@](C)(O)C[C@@H](O1)c1ccc(Cl)cc1 InChI=1S/C15H21ClO2S/c1-3-19-10-13-8-15(2,17)9-14(18-13)11-4-6-12(16)7-5-11/h4-7,13-14,17H,3,8-10H2,1-2H3/t13-,14+,15-/m0/s1 NBAVADMYANAFPV-ZNMIVQPWSA-N 50249344 (2R,4R,6S)-2-(4-chlorophenyl)-6-(ethylthiomethyl)-4-methyltetrahydro-2H-pyran-4-ol::CHEMBL505877 Prostaglandin G/H synthase 2 Ovis aries >10000 ChEMBL 10.1016/j.ejmech.2008.08.008 10.7270/Q2H41R8Q 18835505 Singh, P; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249344&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42599217 104103666 CHEMBL505877 ZINC40834219 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50435882 CCSC[C@@H]1C[C@](C)(O)C[C@@H](O1)c1ccc(Br)cc1 InChI=1S/C15H21BrO2S/c1-3-19-10-13-8-15(2,17)9-14(18-13)11-4-6-12(16)7-5-11/h4-7,13-14,17H,3,8-10H2,1-2H3/t13-,14+,15-/m0/s1 DDRDTFVBIXPAIT-ZNMIVQPWSA-N 50249345 (2R,4R,6S)-2-(4-bromophenyl)-6-(ethylthiomethyl)-4-methyltetrahydro-2H-pyran-4-ol::CHEMBL475423 Prostaglandin G/H synthase 2 Ovis aries >10000 ChEMBL 10.1016/j.ejmech.2008.08.008 10.7270/Q2H41R8Q 18835505 Singh, P; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249345&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42599218 104103667 CHEMBL475423 ZINC40899260 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50435883 C[C@]1(O)C[C@@H](CSC#N)O[C@H](C1)c1ccc(Br)cc1 InChI=1S/C14H16BrNO2S/c1-14(17)6-12(8-19-9-16)18-13(7-14)10-2-4-11(15)5-3-10/h2-5,12-13,17H,6-8H2,1H3/t12-,13+,14-/m0/s1 IHVLVDCCFBGAQA-MJBXVCDLSA-N 50249373 (2R,4R,6S)-2-(4-bromophenyl)-4-methyl-6-(thiocyanatomethyl)tetrahydro-2H-pyran-4-ol::CHEMBL472417 Prostaglandin G/H synthase 2 Ovis aries >10000 ChEMBL 10.1016/j.ejmech.2008.08.008 10.7270/Q2H41R8Q 18835505 Singh, P; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249373&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42599219 104103690 CHEMBL472417 ZINC40914044 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50435884 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.ejmech.2008.08.008 10.7270/Q2H41R8Q 18835505 Singh, P; Bhardwaj, A; Kaur, S; Kumar, S Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50459723 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmcl.2009.04.059 10.7270/Q2CR5T81 19419861 Abdellatif, KR; Chowdhury, MA; Dong, Y; Das, D; Yu, G; Velazquez, CA; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50459724 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 5700 ChEMBL 10.1016/j.bmcl.2009.04.059 10.7270/Q2CR5T81 19419861 Abdellatif, KR; Chowdhury, MA; Dong, Y; Das, D; Yu, G; Velazquez, CA; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50459725 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1016/j.bmcl.2009.04.059 10.7270/Q2CR5T81 19419861 Abdellatif, KR; Chowdhury, MA; Dong, Y; Das, D; Yu, G; Velazquez, CA; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50475758 CC(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C23H20ClN3O/c1-16(28)25-20-13-9-17(10-14-20)22-15-23(18-7-11-19(24)12-8-18)27(26-22)21-5-3-2-4-6-21/h2-14,23H,15H2,1H3,(H,25,28) RHKXSSLIDHBJJW-UHFFFAOYSA-N 50152830 CHEMBL3780916 Prostaglandin G/H synthase 2 Ovis aries 30700 ChEMBL 10.1016/j.bmc.2016.03.032 10.7270/Q2XK8HFX 27025563 Abdel-Sayed, MA; Bayomi, SM; El-Sherbeny, MA; Abdel-Aziz, NI; ElTahir, KE; Shehatou, GS; Abdel-Aziz, AA University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152830&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127031988 340133015 CHEMBL3780916 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50475759 [O-][N+](=O)OCC(=O)N1N=C(CC1c1ccc(cc1)[N+]([O-])=O)c1ccc(F)cc1 InChI=1S/C17H13FN4O6/c18-13-5-1-11(2-6-13)15-9-16(12-3-7-14(8-4-12)21(24)25)20(19-15)17(23)10-28-22(26)27/h1-8,16H,9-10H2 IZJGLXLLLUFYQV-UHFFFAOYSA-N 50152831 CHEMBL3779958 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2016.03.032 10.7270/Q2XK8HFX 27025563 Abdel-Sayed, MA; Bayomi, SM; El-Sherbeny, MA; Abdel-Aziz, NI; ElTahir, KE; Shehatou, GS; Abdel-Aziz, AA University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152831&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127031711 340133016 CHEMBL3779958 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50475760 CC(=O)c1ccc(NCC(=O)N2N=C(CC2c2ccc(cc2)[N+]([O-])=O)c2ccccc2)cc1 InChI=1S/C25H22N4O4/c1-17(30)18-7-11-21(12-8-18)26-16-25(31)28-24(20-9-13-22(14-10-20)29(32)33)15-23(27-28)19-5-3-2-4-6-19/h2-14,24,26H,15-16H2,1H3 SOUWQCNGEBHJRL-UHFFFAOYSA-N 50152832 CHEMBL3781409 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.bmc.2016.03.032 10.7270/Q2XK8HFX 27025563 Abdel-Sayed, MA; Bayomi, SM; El-Sherbeny, MA; Abdel-Aziz, NI; ElTahir, KE; Shehatou, GS; Abdel-Aziz, AA University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152832&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127031712 340133017 CHEMBL3781409 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50475761 CC(=O)c1ccc(NCC(=O)N2N=C(CC2c2ccc(cc2)[N+]([O-])=O)c2ccc(F)cc2)cc1 InChI=1S/C39H50N20O23P4/c40-29-19-33(48-6-44-29)56(10-52-19)1-15(81-85(69,70)76-5-17-23(61)26(64)37(77-17)57-11-53-20-30(41)45-7-49-34(20)57)14(60)2-75-86(71,72)82-28-25(63)16(78-39(28)59-13-55-22-32(43)47-9-51-36(22)59)3-73-83(65)80-27-24(62)18(4-74-84(66,67)68)79-38(27)58-12-54-21-31(42)46-8-50-35(21)58/h6-18,23-28,37-39,60-64,83H,1-5H2,(H,69,70)(H,71,72)(H2,40,44,48)(H2,41,45,49)(H2,42,46,50)(H2,43,47,51)(H2,66,67,68)/p-3/t14-,15+,16-,17-,18-,23-,24-,25-,26-,27-,28-,37-,38-,39-/m1/s1 NBRMDFSUZFIXOQ-SRQDNTBLSA-K 50152833 CHEMBL3781986 Prostaglandin G/H synthase 2 Ovis aries 12100 ChEMBL 10.1016/j.bmc.2016.03.032 10.7270/Q2XK8HFX 27025563 Abdel-Sayed, MA; Bayomi, SM; El-Sherbeny, MA; Abdel-Aziz, NI; ElTahir, KE; Shehatou, GS; Abdel-Aziz, AA University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152833&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127031714 104040854 CHEMBL3781986 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50475762 CC(=O)Nc1ccc(cc1)C1=NN(C(C1)c1ccc(cc1)[N+]([O-])=O)C(C)=O InChI=1S/C39H50N20O23P4/c40-29-19-33(48-6-44-29)56(10-52-19)1-15(14(60)2-73-83(65)80-27-24(62)17(3-74-84(66,67)68)78-38(27)58-12-54-21-31(42)46-8-50-35(21)58)81-85(69,70)75-5-18-25(63)28(39(79-18)59-13-55-22-32(43)47-9-51-36(22)59)82-86(71,72)76-4-16-23(61)26(64)37(77-16)57-11-53-20-30(41)45-7-49-34(20)57/h6-18,23-28,37-39,60-64,83H,1-5H2,(H,69,70)(H,71,72)(H2,40,44,48)(H2,41,45,49)(H2,42,46,50)(H2,43,47,51)(H2,66,67,68)/p-3/t14-,15+,16-,17-,18-,23-,24-,25-,26-,27-,28-,37-,38-,39-/m1/s1 IBDHHNXCJKFLOB-SRQDNTBLSA-K 50152835 CHEMBL3780708 Prostaglandin G/H synthase 2 Ovis aries 14600 ChEMBL 10.1016/j.bmc.2016.03.032 10.7270/Q2XK8HFX 27025563 Abdel-Sayed, MA; Bayomi, SM; El-Sherbeny, MA; Abdel-Aziz, NI; ElTahir, KE; Shehatou, GS; Abdel-Aziz, AA University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152835&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 12843532 104040856 CHEMBL3780708 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50475763 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.bmc.2016.03.032 10.7270/Q2XK8HFX 27025563 Abdel-Sayed, MA; Bayomi, SM; El-Sherbeny, MA; Abdel-Aziz, NI; ElTahir, KE; Shehatou, GS; Abdel-Aziz, AA University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489176 CC(C)Cc1ccc(cc1)[C@H](C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1 HEFNNWSXXWATRW-JTQLQIEISA-N 50169047 (S)-2-(4-Isobutyl-phenyl)-propionic acid::(S)-2-(4-isobutylphenyl)propanoic acid::(S)-ibuprofen::CHEMBL175::DEXIBUPROFEN::IBUPROFEN LYSINE Prostaglandin G/H synthase 2 Ovis aries 265500 ChEMBL 10.1016/j.bmcl.2003.11.066 10.7270/Q25M655Z 15013005 Mittal, S; Malde, A; Selvam, C; Arun, KH; Johar, PS; Jachak, SM; Ramarao, P; Bharatam, PV; Chawla, HP National Institute of Pharmaceutical Education and Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50169047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50169047&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 39912 104053911 5855 CHEMBL175 DB09213 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489308 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489309 NS(=O)(=O)c1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C24H22N4O5S/c25-34(32,33)20-13-11-19(12-14-20)26-21(29)15-16-28-22(30)24(27-23(28)31,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,29)(H,27,31)(H2,25,32,33) IWYSIRLFOMZCSF-UHFFFAOYSA-N 50161267 CHEMBL3785126 Prostaglandin G/H synthase 2 Ovis aries 410 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161267&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127030674 341096868 CHEMBL3785126 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489310 Fc1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C24H20FN3O3/c25-19-11-13-20(14-12-19)26-21(29)15-16-28-22(30)24(27-23(28)31,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14H,15-16H2,(H,26,29)(H,27,31) INQQFIRLBWFBMV-UHFFFAOYSA-N 50161265 CHEMBL3785255 Prostaglandin G/H synthase 2 Ovis aries 10780 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161265&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45901175 341096866 CHEMBL3785255 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489311 COc1ccc(NC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C25H23N3O4/c1-32-21-14-12-20(13-15-21)26-22(29)16-17-28-23(30)25(27-24(28)31,18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16-17H2,1H3,(H,26,29)(H,27,31) IDPGKCGNALPSDI-UHFFFAOYSA-N 50161266 CHEMBL3786019 Prostaglandin G/H synthase 2 Ovis aries 990 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161266&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127031931 341096867 CHEMBL3786019 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489312 COc1cc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc(OC)c1OC InChI=1S/C27H27N3O6/c1-34-21-14-18(15-22(35-2)24(21)36-3)16-28-23(31)17-30-25(32)27(29-26(30)33,19-10-6-4-7-11-19)20-12-8-5-9-13-20/h4-15H,16-17H2,1-3H3,(H,28,31)(H,29,33) WIABGRDVOBDKBC-UHFFFAOYSA-N 50161264 CHEMBL3786688 Prostaglandin G/H synthase 2 Ovis aries 610 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161264&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 27926089 341096865 CHEMBL3786688 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489314 Fc1ccc(cc1)C(=O)CN1C(=O)NC(C1=O)(c1ccccc1)c1ccccc1 InChI=1S/C23H17FN2O3/c24-19-13-11-16(12-14-19)20(27)15-26-21(28)23(25-22(26)29,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14H,15H2,(H,25,29) CUQSBYJYIVHHFX-UHFFFAOYSA-N 50161271 CHEMBL3785540 Prostaglandin G/H synthase 2 Ovis aries 25220 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161271&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 4810444 341096871 CHEMBL3785540 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489315 NS(=O)(=O)c1ccc(NC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C23H20N4O5S/c24-33(31,32)19-13-11-18(12-14-19)25-20(28)15-27-21(29)23(26-22(27)30,16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14H,15H2,(H,25,28)(H,26,30)(H2,24,31,32) JUXFMQGMNJPCTF-UHFFFAOYSA-N 50161259 CHEMBL3785358 Prostaglandin G/H synthase 2 Ovis aries 700 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161259&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2077907 341096861 CHEMBL3785358 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489316 COc1ccc(cc1)C(=O)CN1C(=O)NC(C1=O)(c1ccccc1)c1ccccc1 InChI=1S/C24H20N2O4/c1-30-20-14-12-17(13-15-20)21(27)16-26-22(28)24(25-23(26)29,18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-15H,16H2,1H3,(H,25,29) BZIXIEVSXWQXTK-UHFFFAOYSA-N 50161274 CHEMBL3785696 Prostaglandin G/H synthase 2 Ovis aries 25010 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161274&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search O5J 6P9P 8005518 341096873 CHEMBL3785696 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489317 NS(=O)(=O)c1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C24H22N4O5S/c25-34(32,33)20-13-11-17(12-14-20)15-26-21(29)16-28-22(30)24(27-23(28)31,18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14H,15-16H2,(H,26,29)(H,27,31)(H2,25,32,33) NGZCUAPCJNBUEU-UHFFFAOYSA-N 50161263 CHEMBL3786373 Prostaglandin G/H synthase 2 Ovis aries 440 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161263&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127033959 341096864 CHEMBL3786373 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489318 COc1ccc(CNC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C26H25N3O4/c1-33-22-14-12-19(13-15-22)18-27-23(30)16-17-29-24(31)26(28-25(29)32,20-8-4-2-5-9-20)21-10-6-3-7-11-21/h2-15H,16-18H2,1H3,(H,27,30)(H,28,32) LQYKWDLNENUREX-UHFFFAOYSA-N 50161270 CHEMBL3786565 Prostaglandin G/H synthase 2 Ovis aries 1320 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161270&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127033114 341096870 CHEMBL3786565 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489319 Fc1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C24H20FN3O3/c25-20-13-11-17(12-14-20)15-26-21(29)16-28-22(30)24(27-23(28)31,18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14H,15-16H2,(H,26,29)(H,27,31) FGXHOVIQUSBFGT-UHFFFAOYSA-N 50161260 CHEMBL1702044 Prostaglandin G/H synthase 2 Ovis aries 7210 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161260&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2103639 341096862 CHEMBL1702044 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489320 Fc1ccc(NC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C23H18FN3O3/c24-18-11-13-19(14-12-18)25-20(28)15-27-21(29)23(26-22(27)30,16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14H,15H2,(H,25,28)(H,26,30) ZPYRUOYVPBBTOV-UHFFFAOYSA-N 50161257 CHEMBL3786872 Prostaglandin G/H synthase 2 Ovis aries 14770 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161257&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 8002008 341096859 CHEMBL3786872 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489321 Fc1ccc(CNC(=O)CCN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C25H22FN3O3/c26-21-13-11-18(12-14-21)17-27-22(30)15-16-29-23(31)25(28-24(29)32,19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-14H,15-17H2,(H,27,30)(H,28,32) ILUUXEPPRBUCGF-UHFFFAOYSA-N 50161269 CHEMBL3787062 Prostaglandin G/H synthase 2 Ovis aries 10780 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161269&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127031547 341096869 CHEMBL3787062 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489322 COc1ccc(NC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C24H21N3O4/c1-31-20-14-12-19(13-15-20)25-21(28)16-27-22(29)24(26-23(27)30,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,25,28)(H,26,30) MOLAZBBLMYUCJX-UHFFFAOYSA-N 50161258 CHEMBL1301905 Prostaglandin G/H synthase 2 Ovis aries 6540 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161258&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 8158990 341096860 CHEMBL1301905 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50489324 COc1ccc(CNC(=O)CN2C(=O)NC(C2=O)(c2ccccc2)c2ccccc2)cc1 InChI=1S/C25H23N3O4/c1-32-21-14-12-18(13-15-21)16-26-22(29)17-28-23(30)25(27-24(28)31,19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15H,16-17H2,1H3,(H,26,29)(H,27,31) NRAWEDFFNPLFLY-UHFFFAOYSA-N 50161261 CHEMBL2139982 Prostaglandin G/H synthase 2 Ovis aries 1300 ChEMBL 10.1016/j.ejmech.2016.03.011 10.7270/Q22N545K 26999325 Abdel-Aziz, AA; El-Azab, AS; Abou-Zeid, LA; ElTahir, KE; Abdel-Aziz, NI; Ayyad, RR; Al-Obaid, AM King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161261&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2119655 341096863 CHEMBL2139982 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506240 COc1ccc(\C=C\C(=O)c2sc(nc2C)-c2ccccc2)cc1 InChI=1S/C20H17NO2S/c1-14-19(24-20(21-14)16-6-4-3-5-7-16)18(22)13-10-15-8-11-17(23-2)12-9-15/h3-13H,1-2H3/b13-10+ CDWXQQCOZHDTJF-JLHYYAGUSA-N 50185051 CHEMBL1537950 Prostaglandin G/H synthase 2 Ovis aries 2370 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185051&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5707201 346550506 CHEMBL1537950 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506241 CN(C)\C=N\S(=O)(=O)c1ccc(cc1)-n1ccc(n1)-c1sc(nc1C)-c1ccccc1 InChI=1S/C22H21N5O2S2/c1-16-21(30-22(24-16)17-7-5-4-6-8-17)20-13-14-27(25-20)18-9-11-19(12-10-18)31(28,29)23-15-26(2)3/h4-15H,1-3H3/b23-15+ UFJGBUCTTJVSSD-HZHRSRAPSA-N 50185052 CHEMBL3822637 Prostaglandin G/H synthase 2 Ovis aries 2410 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185052&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127052868 346550507 CHEMBL3822637 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506242 C\C(=N/Nc1ccc(cc1)S(N)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C18H18N4O2S2/c1-12-17(25-18(20-12)14-6-4-3-5-7-14)13(2)21-22-15-8-10-16(11-9-15)26(19,23)24/h3-11,22H,1-2H3,(H2,19,23,24)/b21-13+ MDEFTIHECCJTFN-FYJGNVAPSA-N 50185053 CHEMBL3822602 Prostaglandin G/H synthase 2 Ovis aries 2230 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185053&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127052867 346550508 CHEMBL3822602 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506243 C\C(=N/Nc1ccc(cc1)S(C)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C19H19N3O2S2/c1-13-18(25-19(20-13)15-7-5-4-6-8-15)14(2)21-22-16-9-11-17(12-10-16)26(3,23)24/h4-12,22H,1-3H3/b21-14+ WBZJWJHVENOYEW-KGENOOAVSA-N 50185054 CHEMBL3822882 Prostaglandin G/H synthase 2 Ovis aries 1110 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185054&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127049240 104069296 CHEMBL3822882 ZINC36311014 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506244 Cc1nc(sc1-c1ccnn1-c1ccc(cc1)S(N)(=O)=O)-c1ccccc1 InChI=1S/C19H16N4O2S2/c1-13-18(26-19(22-13)14-5-3-2-4-6-14)17-11-12-21-23(17)15-7-9-16(10-8-15)27(20,24)25/h2-12H,1H3,(H2,20,24,25) CZUQGOKULOSSJO-UHFFFAOYSA-N 50185055 CHEMBL3822900 Prostaglandin G/H synthase 2 Ovis aries 2230 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185055&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127052866 104069297 CHEMBL3822900 ZINC28572697 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506323 Cc1nc(sc1-c1ccnn1-c1ccc(cc1)S(C)(=O)=O)-c1ccccc1 InChI=1S/C20H17N3O2S2/c1-14-19(26-20(22-14)15-6-4-3-5-7-15)18-12-13-21-23(18)16-8-10-17(11-9-16)27(2,24)25/h3-13H,1-2H3 SPIQOKZSPASBRN-UHFFFAOYSA-N 50185056 CHEMBL3824335 Prostaglandin G/H synthase 2 Ovis aries 2970 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185056&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127053152 346550509 CHEMBL3824335 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506324 Cc1nc(sc1-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F)-c1ccccc1 InChI=1S/C20H15F3N4O2S2/c1-12-18(30-19(25-12)13-5-3-2-4-6-13)16-11-17(20(21,22)23)26-27(16)14-7-9-15(10-8-14)31(24,28)29/h2-11H,1H3,(H2,24,28,29) RHBMPLODTPIHHK-UHFFFAOYSA-N 50185121 CHEMBL3823010 Prostaglandin G/H synthase 2 Ovis aries 1710 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185121&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127053151 104069362 CHEMBL3823010 ZINC36088700 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50506325 Cc1nc(sc1-c1cc(nn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F)-c1ccccc1 InChI=1S/C21H16F3N3O2S2/c1-13-19(30-20(25-13)14-6-4-3-5-7-14)17-12-18(21(22,23)24)26-27(17)15-8-10-16(11-9-15)31(2,28)29/h3-12H,1-2H3 COLGOADUHDTEQC-UHFFFAOYSA-N 50185126 CHEMBL3822823 Prostaglandin G/H synthase 2 Ovis aries 980 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185126&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127053150 104069367 CHEMBL3822823 ZINC36088491 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50503368 CS(=O)(=O)Nc1ccc(cc1Oc1ccc(I)cc1)[N+]([O-])=O InChI=1S/C13H11IN2O5S/c1-22(19,20)15-12-7-4-10(16(17)18)8-13(12)21-11-5-2-9(14)3-6-11/h2-8,15H,1H3 ZWLWGYXTOAVBOO-UHFFFAOYSA-N 50182889 CHEMBL3818849 Prostaglandin G/H synthase 2 Ovis aries 470 ChEMBL 10.1016/j.bmc.2016.06.015 10.7270/Q2HX1FMD 27325447 Yamamoto, Y; Arai, J; Hisa, T; Saito, Y; Mukai, T; Ohshima, T; Maeda, M; Yamamoto, F Tohoku Medical and Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182889&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122390407 104067504 CHEMBL3818849 ZINC36286954 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50503369 CS(=O)(=O)Nc1ccc(cc1Oc1cccc(I)c1)[N+]([O-])=O InChI=1S/C13H11IN2O5S/c1-22(19,20)15-12-6-5-10(16(17)18)8-13(12)21-11-4-2-3-9(14)7-11/h2-8,15H,1H3 ZKYYRZLLBBKBDY-UHFFFAOYSA-N 50182989 CHEMBL3819010 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2016.06.015 10.7270/Q2HX1FMD 27325447 Yamamoto, Y; Arai, J; Hisa, T; Saito, Y; Mukai, T; Ohshima, T; Maeda, M; Yamamoto, F Tohoku Medical and Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182989&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122390408 346550137 CHEMBL3819010 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50503370 CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1I)[N+]([O-])=O InChI=1S/C13H11IN2O5S/c1-22(19,20)15-11-7-6-9(16(17)18)8-13(11)21-12-5-3-2-4-10(12)14/h2-8,15H,1H3 HZQVRZWDGULYGT-UHFFFAOYSA-N 50182990 CHEMBL3818762 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2016.06.015 10.7270/Q2HX1FMD 27325447 Yamamoto, Y; Arai, J; Hisa, T; Saito, Y; Mukai, T; Ohshima, T; Maeda, M; Yamamoto, F Tohoku Medical and Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182990&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122390406 346550138 CHEMBL3818762 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50516403 [O-][N+](=O)c1ccc(cc1)-c1nnc(CCC(=O)c2ccc(cc2)-c2ccccc2)o1 InChI=1S/C23H17N3O4/c27-21(18-8-6-17(7-9-18)16-4-2-1-3-5-16)14-15-22-24-25-23(30-22)19-10-12-20(13-11-19)26(28)29/h1-13H,14-15H2 GOTQYRFGMPNASB-UHFFFAOYSA-N 50297558 3-[5-(4-Nitrophenyl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-one::CHEMBL564173 Prostaglandin G/H synthase 2 Ovis aries 8200 ChEMBL 10.1016/j.ejmech.2009.04.009 10.7270/Q2J1036V 19457595 Husain, A; Ahmad, A; Alam, MM; Ajmal, M; Ahuja, P Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297558&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 16656658 104139089 CHEMBL564173 ZINC43074650 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50516404 COc1ccc(cc1)-c1nnc(CCC(=O)c2ccc(cc2)-c2ccccc2)o1 InChI=1S/C24H20N2O3/c1-28-21-13-11-20(12-14-21)24-26-25-23(29-24)16-15-22(27)19-9-7-18(8-10-19)17-5-3-2-4-6-17/h2-14H,15-16H2,1H3 VWPUHMQWDHNIOJ-UHFFFAOYSA-N 50297559 3-[5-(4-Methoxyophenyl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-one::CHEMBL559421 Prostaglandin G/H synthase 2 Ovis aries 1800 ChEMBL 10.1016/j.ejmech.2009.04.009 10.7270/Q2J1036V 19457595 Husain, A; Ahmad, A; Alam, MM; Ajmal, M; Ahuja, P Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297559&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 16656656 104139090 CHEMBL559421 ZINC43076398 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50516405 COc1ccc(cc1OC)-c1nnc(CCC(=O)c2ccc(cc2)-c2ccccc2)o1 InChI=1S/C25H22N2O4/c1-29-22-14-12-20(16-23(22)30-2)25-27-26-24(31-25)15-13-21(28)19-10-8-18(9-11-19)17-6-4-3-5-7-17/h3-12,14,16H,13,15H2,1-2H3 ROCQPPBVFBLOQQ-UHFFFAOYSA-N 50297560 3-[5-(3,4-Dimethoxy phenyl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-one::CHEMBL549802 Prostaglandin G/H synthase 2 Ovis aries 1500 ChEMBL 10.1016/j.ejmech.2009.04.009 10.7270/Q2J1036V 19457595 Husain, A; Ahmad, A; Alam, MM; Ajmal, M; Ahuja, P Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297560&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 16656657 104139091 CHEMBL549802 ZINC43011245 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50516406 O=C(CCc1nnc(COc2ccc3ccccc3c2)o1)c1ccc(cc1)-c1ccccc1 InChI=1S/C28H22N2O3/c31-26(23-12-10-22(11-13-23)20-6-2-1-3-7-20)16-17-27-29-30-28(33-27)19-32-25-15-14-21-8-4-5-9-24(21)18-25/h1-15,18H,16-17,19H2 UAQJGVXATPNYLX-UHFFFAOYSA-N 50297561 3-[(5-(2-Naphthoxymethyl)-1,3,4-oxadiazol-2-yl)-1-(biphenyl-4-yl)propan-1-one::CHEMBL559814 Prostaglandin G/H synthase 2 Ovis aries 2500 ChEMBL 10.1016/j.ejmech.2009.04.009 10.7270/Q2J1036V 19457595 Husain, A; Ahmad, A; Alam, MM; Ajmal, M; Ahuja, P Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297561&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44226773 104139092 CHEMBL559814 ZINC43072075 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50516407 OC(=O)CCC(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19) ZPAKPRAICRBAOD-UHFFFAOYSA-N 50240374 3-(4-biphenylylcarbonyl)propionic acid::3-(4-phenylbenzoyl)propionic acid::4-(4-biphenylyl)-4-oxobutyric acid::4-[1,1'-biphenyl-4-yl]-4-oxobutanoic acid::4-biphenyl-4-yl-4-oxobutanoic acid::CHEMBL277522::Fenbufen::gamma-oxo(1,1'-biphenyl)-4-butanoic acid Prostaglandin G/H synthase 2 Ovis aries 8100 ChEMBL 10.1016/j.ejmech.2009.04.009 10.7270/Q2J1036V 19457595 Husain, A; Ahmad, A; Alam, MM; Ajmal, M; Ahuja, P Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240374&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 3335 104098254 31599 CHEMBL277522 DB08981 ZINC00001427 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50516408 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.ejmech.2009.04.009 10.7270/Q2J1036V 19457595 Husain, A; Ahmad, A; Alam, MM; Ajmal, M; Ahuja, P Hamdard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50510977 CS(=O)(=O)c1ccc(cc1)C1Sc2ccccc2C(=O)N1c1ccccc1 InChI=1S/C21H17NO3S2/c1-27(24,25)17-13-11-15(12-14-17)21-22(16-7-3-2-4-8-16)20(23)18-9-5-6-10-19(18)26-21/h2-14,21H,1H3 AQSYWWXIPBNUSM-UHFFFAOYSA-N 50295360 2-(4-Methylsulfonylphenyl)-3-phenyl-1,3-benzthiazinan-4-one::CHEMBL571455 Prostaglandin G/H synthase 2 Ovis aries 120 ChEMBL 10.1016/j.bmc.2009.06.056 10.7270/Q2XS5VDJ 19596198 Zarghi, A; Zebardast, T; Daraie, B; Hedayati, M Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45272418 104136891 CHEMBL571455 ZINC43023214 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50510978 CS(=O)(=O)c1ccc(cc1)C1Sc2ccccc2C(=O)N1c1ccc(F)cc1 InChI=1S/C21H16FNO3S2/c1-28(25,26)17-12-6-14(7-13-17)21-23(16-10-8-15(22)9-11-16)20(24)18-4-2-3-5-19(18)27-21/h2-13,21H,1H3 CAZFILKGZKZPEU-UHFFFAOYSA-N 50295359 3-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)-1,3-benzthiazinan-4-one::CHEMBL549958 Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1016/j.bmc.2009.06.056 10.7270/Q2XS5VDJ 19596198 Zarghi, A; Zebardast, T; Daraie, B; Hedayati, M Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295359&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44517771 104136890 CHEMBL549958 ZINC43016391 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50510979 Cc1ccc(cc1)N1C(Sc2ccccc2C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C22H19NO3S2/c1-15-7-11-17(12-8-15)23-21(24)19-5-3-4-6-20(19)27-22(23)16-9-13-18(14-10-16)28(2,25)26/h3-14,22H,1-2H3 XCNJIEUIDFBRCJ-UHFFFAOYSA-N 50295358 3-(4-Methylphenyl)-2-(4-methylsulfonylphenyl)-1,3-benzthiazinan-4-one::CHEMBL557908 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmc.2009.06.056 10.7270/Q2XS5VDJ 19596198 Zarghi, A; Zebardast, T; Daraie, B; Hedayati, M Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295358&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45273288 104136889 CHEMBL557908 ZINC43059574 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50510980 COc1ccc(cc1)N1C(Sc2ccccc2C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C22H19NO4S2/c1-27-17-11-9-16(10-12-17)23-21(24)19-5-3-4-6-20(19)28-22(23)15-7-13-18(14-8-15)29(2,25)26/h3-14,22H,1-2H3 UOAHFKDLHQRAHA-UHFFFAOYSA-N 50295357 3-(4-Methoxyphenyl)-2-(4-methylsulfonylphenyl)-1,3-benzthiazinan-4-one::CHEMBL563354 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.bmc.2009.06.056 10.7270/Q2XS5VDJ 19596198 Zarghi, A; Zebardast, T; Daraie, B; Hedayati, M Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295357&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45267271 104136888 CHEMBL563354 ZINC43069008 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50510981 CS(=O)(=O)c1ccc(cc1)C1Sc2ccccc2C(=O)N1Cc1ccccc1 InChI=1S/C22H19NO3S2/c1-28(25,26)18-13-11-17(12-14-18)22-23(15-16-7-3-2-4-8-16)21(24)19-9-5-6-10-20(19)27-22/h2-14,22H,15H2,1H3 YOIIVBKCDGFPTQ-UHFFFAOYSA-N 50295356 3-Benzyl-2-(4-methylsulfonylphenyl)-1,3-benzthiazinan-4-one::CHEMBL561055 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2009.06.056 10.7270/Q2XS5VDJ 19596198 Zarghi, A; Zebardast, T; Daraie, B; Hedayati, M Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295356&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45267272 104136887 CHEMBL561055 ZINC43069016 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50510982 CS(=O)(=O)c1ccc(cc1)C1Sc2ccccc2C(=O)N1CCc1ccccc1 InChI=1S/C23H21NO3S2/c1-29(26,27)19-13-11-18(12-14-19)23-24(16-15-17-7-3-2-4-8-17)22(25)20-9-5-6-10-21(20)28-23/h2-14,23H,15-16H2,1H3 SQDQYYZHLUAFFO-UHFFFAOYSA-N 50295361 2-(4-Methylsulfonylphenyl)-3-phenethyl-1,3-benzthiazinan-4-one::CHEMBL557909 Prostaglandin G/H synthase 2 Ovis aries 80 ChEMBL 10.1016/j.bmc.2009.06.056 10.7270/Q2XS5VDJ 19596198 Zarghi, A; Zebardast, T; Daraie, B; Hedayati, M Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295361&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45273289 104136892 CHEMBL557909 ZINC43060113 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50510983 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmc.2009.06.056 10.7270/Q2XS5VDJ 19596198 Zarghi, A; Zebardast, T; Daraie, B; Hedayati, M Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501580 Sc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C15H13N3OS/c19-14-12-6-1-2-7-13(12)17-15(20)18(14)10-8-11-5-3-4-9-16-11/h1-7,9H,8,10H2,(H,17,20) JRNVKGXYIMWMPQ-UHFFFAOYSA-N 50180629 CHEMBL3814962 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180629&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 4560677 346549715 CHEMBL3814962 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501581 Fc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc2ccccn2)cc1 InChI=1S/C23H19FN4O2S/c24-16-8-10-18(11-9-16)26-21(29)15-31-23-27-20-7-2-1-6-19(20)22(30)28(23)14-12-17-5-3-4-13-25-17/h1-11,13H,12,14-15H2,(H,26,29) UEHUAZSKQBFLTL-UHFFFAOYSA-N 50180630 CHEMBL3814616 Prostaglandin G/H synthase 2 Ovis aries 330 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180630&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127051441 346549716 CHEMBL3814616 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501582 COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc2ccccn2)cc1 InChI=1S/C24H22N4O3S/c1-31-19-11-9-18(10-12-19)26-22(29)16-32-24-27-21-8-3-2-7-20(21)23(30)28(24)15-13-17-6-4-5-14-25-17/h2-12,14H,13,15-16H2,1H3,(H,26,29) IEFZMSHPGLWDFW-UHFFFAOYSA-N 50180631 CHEMBL3813973 Prostaglandin G/H synthase 2 Ovis aries 800 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180631&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127051442 346549717 CHEMBL3813973 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501583 COc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2CCc2ccccn2)cc(OC)c1OC InChI=1S/C26H26N4O5S/c1-33-21-14-18(15-22(34-2)24(21)35-3)28-23(31)16-36-26-29-20-10-5-4-9-19(20)25(32)30(26)13-11-17-8-6-7-12-27-17/h4-10,12,14-15H,11,13,16H2,1-3H3,(H,28,31) YNMXZGHQHZPKPB-UHFFFAOYSA-N 50180632 CHEMBL3813998 Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180632&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127050544 346549718 CHEMBL3813998 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501584 COc1cc(NC(=O)CCSc2nc3ccccc3c(=O)n2CCc2ccccn2)cc(OC)c1OC InChI=1S/C27H28N4O5S/c1-34-22-16-19(17-23(35-2)25(22)36-3)29-24(32)12-15-37-27-30-21-10-5-4-9-20(21)26(33)31(27)14-11-18-8-6-7-13-28-18/h4-10,13,16-17H,11-12,14-15H2,1-3H3,(H,29,32) AQWPREYWIRWXQH-UHFFFAOYSA-N 50180633 CHEMBL3814898 Prostaglandin G/H synthase 2 Ovis aries 700 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180633&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127050546 346549719 CHEMBL3814898 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501585 Fc1ccc(cc1)C(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C23H18FN3O2S/c24-17-10-8-16(9-11-17)21(28)15-30-23-26-20-7-2-1-6-19(20)22(29)27(23)14-12-18-5-3-4-13-25-18/h1-11,13H,12,14-15H2 ZITOWKNWFUMQIP-UHFFFAOYSA-N 50180634 CHEMBL3814371 Prostaglandin G/H synthase 2 Ovis aries 10400 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180634&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127050876 346549720 CHEMBL3814371 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501586 NNC(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C17H17N5O2S/c18-21-15(23)11-25-17-20-14-7-2-1-6-13(14)16(24)22(17)10-8-12-5-3-4-9-19-12/h1-7,9H,8,10-11,18H2,(H,21,23) IAQJJEKONQRALD-UHFFFAOYSA-N 50180635 CHEMBL3815106 Prostaglandin G/H synthase 2 Ovis aries 700 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180635&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127049944 346549721 CHEMBL3815106 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50501587 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.bmc.2016.06.026 10.7270/Q2QV3PDJ 27344214 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KE; Mohamed, MA; Abu El-Enin, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50505996 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50505997 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 1540 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50505998 COc1ccc(cc1)[C@@H]1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C26H24N4O3S2/c1-17-25(34-26(28-17)19-6-4-3-5-7-19)23-16-24(18-8-12-21(33-2)13-9-18)30(29-23)20-10-14-22(15-11-20)35(27,31)32/h3-15,24H,16H2,1-2H3,(H2,27,31,32)/t24-/m0/s1 VUOLWEHRDLZMSR-DEOSSOPVSA-N 50185049 CHEMBL3824017 Prostaglandin G/H synthase 2 Ovis aries 1760 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185049&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127048941 346550505 CHEMBL3824017 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50505999 COc1ccc(cc1)[C@@H]1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C27H25N3O3S2/c1-18-26(34-27(28-18)20-7-5-4-6-8-20)24-17-25(19-9-13-22(33-2)14-10-19)30(29-24)21-11-15-23(16-12-21)35(3,31)32/h4-16,25H,17H2,1-3H3/t25-/m0/s1 IKOCQRADEXXKQB-VWLOTQADSA-N 50185050 CHEMBL3823621 Prostaglandin G/H synthase 2 Ovis aries 1140 ChEMBL 10.1016/j.ejmech.2016.04.049 10.7270/Q2X350D9 27131067 Abdelall, EK; Kamel, GM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50185050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50185050&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127048940 104069295 CHEMBL3823621 ZINC35933813 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512428 Oc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2 FVYXIJYOAGAUQK-UHFFFAOYSA-N 50157304 3',5-di-2-propenyl-1,1'-biphenyl-2,4'-diol::3',5-diallylbiphenyl-2,4'-diol::5,3''-Diallyl-biphenyl-2,4''-diol::5,3'-diallyl-biphenyl-2,4'-diol::CHEMBL16901::HONOKIOL::Honokiol, HO::cid_72303 Prostaglandin G/H synthase 2 Ovis aries 2100 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157304&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 72303 104044313 CHEMBL16901 C10630 ZINC00001536 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512429 COc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O InChI=1S/C19H20O2/c1-4-6-14-8-10-18(20)17(12-14)15-9-11-19(21-3)16(13-15)7-5-2/h4-5,8-13,20H,1-2,6-7H2,3H3 OQFHJKZVOALSPV-UHFFFAOYSA-N 50295926 4'-O-methylhonokiol, MH::4-methoxyhonokiol::5,3'-Diallyl-4'-methoxy-biphenyl-2-ol::CHEMBL89700::Magreth-14a::Methylhonokiol Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295926&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155160 104137457 CHEMBL89700 ZINC01566147 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512430 COc1ccc(cc1CC=C)-c1cc(CC=C)ccc1OC InChI=1S/C20H22O2/c1-5-7-15-9-11-20(22-4)18(13-15)16-10-12-19(21-3)17(14-16)8-6-2/h5-6,9-14H,1-2,7-8H2,3-4H3 GDCJELDNRAWYTE-UHFFFAOYSA-N 50295927 2,4'-Dimethoxy-5,3'-di-(2-propenyl)-biphenyl::5,3'-Diallyl-2,4'-dimethoxy-biphenyl::CHEMBL89828 Prostaglandin G/H synthase 2 Ovis aries 7700 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295927&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 325144 104137458 CHEMBL89828 ZINC01566148 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512431 CCCc1ccc(O)c(c1)-c1ccc(O)c(CCC)c1 InChI=1S/C18H22O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h7-12,19-20H,3-6H2,1-2H3 PJBHWFHBOPMXAM-UHFFFAOYSA-N 50157312 5,3''-Dipropyl-biphenyl-2,4''-diol::5,3'-Dipropyl-biphenyl-2,4'-diol::CHEMBL330227::Magreth-2 Prostaglandin G/H synthase 2 Ovis aries 2100 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157312&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9900113 104044314 CHEMBL330227 ZINC26578728 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512432 CCCc1ccc(OC)c(c1)-c1ccc(OC)c(CCC)c1 InChI=1S/C20H26O2/c1-5-7-15-9-11-20(22-4)18(13-15)16-10-12-19(21-3)17(14-16)8-6-2/h9-14H,5-8H2,1-4H3 GLDMMYBVNSMLGE-UHFFFAOYSA-N 50295928 2,4'-Dimethoxy-5,3'-dipropyl-biphenyl::CHEMBL560262 Prostaglandin G/H synthase 2 Ovis aries 6900 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295928&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45267390 104137459 CHEMBL560262 ZINC43078155 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512433 COc1ccc(cc1CC=C)-c1cc(CC=C)ccc1OC(C)=O InChI=1S/C21H22O3/c1-5-7-16-9-11-21(24-15(3)22)19(13-16)17-10-12-20(23-4)18(14-17)8-6-2/h5-6,9-14H,1-2,7-8H2,3-4H3 AFIDLYJKMRNHGQ-UHFFFAOYSA-N 50295921 2-Acetoxy-4'-methoxy-5,3'-di-(2-propenyl)-biphenyl::CHEMBL551195 Prostaglandin G/H synthase 2 Ovis aries 4900 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295921&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45269977 104137452 CHEMBL551195 ZINC42920618 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512434 COc1ccc(cc1\C=C\C)-c1cc(CC=C)ccc1O InChI=1S/C19H20O2/c1-4-6-14-8-10-18(20)17(12-14)15-9-11-19(21-3)16(13-15)7-5-2/h4-5,7-13,20H,1,6H2,2-3H3/b7-5+ IDZDKMNEPBYXQX-FNORWQNLSA-N 50295923 4'-Methoxy-3'-(E)-propenyl)-5-(2-propenyl)-biphenyl-2-ol::CHEMBL549698::Magreth-3a::Magreth-3b Prostaglandin G/H synthase 2 Ovis aries 200 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295923&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44241602 104137454 CHEMBL549698 ZINC43013277 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512435 COc1ccc(cc1\C=C/C)-c1cc(CC=C)ccc1O InChI=1S/C19H20O2/c1-4-6-14-8-10-18(20)17(12-14)15-9-11-19(21-3)16(13-15)7-5-2/h4-5,7-13,20H,1,6H2,2-3H3/b7-5- IDZDKMNEPBYXQX-ALCCZGGFSA-N 50295924 4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-biphenyl-2-ol::CHEMBL557713 Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295924&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45273399 104137455 CHEMBL557713 ZINC42921414 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512436 C\C=C\c1cc(ccc1O)-c1cc(CC=C)ccc1O InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,6-12,19-20H,1,5H2,2H3/b6-4+ MHZPQXNOHIORFI-GQCTYLIASA-N 50295925 (E)-3'-Propenyl)-5-(2-propenyl)-biphenyl-2,4'-diol::CHEMBL569136::Magreth-4 Prostaglandin G/H synthase 2 Ovis aries 2700 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295925&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44241601 104137456 CHEMBL569136 ZINC43011338 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50512437 CS(=O)(=O)Nc1ccc(cc1OC1CCCCC1)[N+]([O-])=O InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 KTDZCOWXCWUPEO-UHFFFAOYSA-N 50029593 CHEMBL7162::N-(2-(cyclohexyloxy)-4-nitrophenyl)methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide(NS-398)::N-[2-(cyclohexyloxy)-4-nitrophenyl]methane sulfonamide::N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulfonamide::N-{2-(cyclohexyloxy)-4-[hydroxy(oxido)amino]phenyl}methanesulfonamide::NS-398::NS398 Prostaglandin G/H synthase 2 Ovis aries 2600 ChEMBL 10.1016/j.bmc.2009.05.018 10.7270/Q2SX6D9B 19481465 Schuhly, W; Hufner, A; Pferschy-Wenzig, EM; Prettner, E; Adams, M; Bodensieck, A; Kunert, O; Oluwemimo, A; Haslinger, E; Bauer, R Karl-Franzens-Universit£t Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029593&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NS4 3QMO 4553 103938654 73458 CHEMBL7162 ZINC03791739 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50549052 CS(=O)(=O)c1ccc(cc1)-c1nc2ccccc2cc1-c1ccccc1 InChI=1S/C22H17NO2S/c1-26(24,25)19-13-11-17(12-14-19)22-20(16-7-3-2-4-8-16)15-18-9-5-6-10-21(18)23-22/h2-15H,1H3 OPLJPOZQZWTQDV-UHFFFAOYSA-N 50306353 2-(4-(methylsulfonyl)phenyl)-3-phenylquinoline::CHEMBL598330 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.bmc.2009.12.060 10.7270/Q2V40V94 20061161 Ghodsi, R; Zarghi, A; Daraei, B; Hedayati, M Shahid Beheshti University MC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306353&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46232132 104160714 CHEMBL598330 ZINC45366712 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50549054 Cc1c(-c2ccccc2)c(nc2ccccc12)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C23H19NO2S/c1-16-20-10-6-7-11-21(20)24-23(22(16)17-8-4-3-5-9-17)18-12-14-19(15-13-18)27(2,25)26/h3-15H,1-2H3 XQCBMHKEPWWBCB-UHFFFAOYSA-N 50306354 4-methyl-2-(4-methylsulfonyl)phenyl)-3-phenylquinoline::CHEMBL598331 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.bmc.2009.12.060 10.7270/Q2V40V94 20061161 Ghodsi, R; Zarghi, A; Daraei, B; Hedayati, M Shahid Beheshti University MC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306354&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46232133 104160715 CHEMBL598331 ZINC45366716 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50549056 CS(=O)(=O)c1ccc(cc1)-c1nc2ccccc2c(-c2ccccc2)c1-c1ccccc1 InChI=1S/C28H21NO2S/c1-32(30,31)23-18-16-22(17-19-23)28-27(21-12-6-3-7-13-21)26(20-10-4-2-5-11-20)24-14-8-9-15-25(24)29-28/h2-19H,1H3 LUROKNODFIRYMB-UHFFFAOYSA-N 50306355 3,4-diphenyl-2-(4-methylsulfonyl)phenyl)-quinoline::CHEMBL597903 Prostaglandin G/H synthase 2 Ovis aries 130 ChEMBL 10.1016/j.bmc.2009.12.060 10.7270/Q2V40V94 20061161 Ghodsi, R; Zarghi, A; Daraei, B; Hedayati, M Shahid Beheshti University MC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306355&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46232185 104160716 CHEMBL597903 ZINC45356492 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50549058 CS(=O)(=O)c1ccc(cc1)-c1nc2ccccc2c(N)c1-c1ccccc1 InChI=1S/C22H18N2O2S/c1-27(25,26)17-13-11-16(12-14-17)22-20(15-7-3-2-4-8-15)21(23)18-9-5-6-10-19(18)24-22/h2-14H,1H3,(H2,23,24) DQFDBTGRKSFVFQ-UHFFFAOYSA-N 50306356 4-amino-2-(4-(methylsulfonyl)phenyl)-3-phenylquinoline::CHEMBL597901 Prostaglandin G/H synthase 2 Ovis aries 80 ChEMBL 10.1016/j.bmc.2009.12.060 10.7270/Q2V40V94 20061161 Ghodsi, R; Zarghi, A; Daraei, B; Hedayati, M Shahid Beheshti University MC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306356&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46232186 104160717 CHEMBL597901 ZINC45356482 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50549060 CS(=O)(=O)c1ccc(cc1)-c1nc2ccccc2c(C(O)=O)c1-c1ccccc1 InChI=1S/C23H17NO4S/c1-29(27,28)17-13-11-16(12-14-17)22-20(15-7-3-2-4-8-15)21(23(25)26)18-9-5-6-10-19(18)24-22/h2-14H,1H3,(H,25,26) QIPZVWKUJCEWTF-UHFFFAOYSA-N 50306357 2-(4-(methylsulfonyl)phenyl)-3-phenylquinoline-4-carboxylic acid::CHEMBL597902 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2009.12.060 10.7270/Q2V40V94 20061161 Ghodsi, R; Zarghi, A; Daraei, B; Hedayati, M Shahid Beheshti University MC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306357&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46232187 104160718 CHEMBL597902 ZINC45356487 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50549062 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmc.2009.12.060 10.7270/Q2V40V94 20061161 Ghodsi, R; Zarghi, A; Daraei, B; Hedayati, M Shahid Beheshti University MC http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536294 COc1ccc2[nH]c(cc2c1)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C16H15NO3S/c1-20-13-5-8-15-12(9-13)10-16(17-15)11-3-6-14(7-4-11)21(2,18)19/h3-10,17H,1-2H3 RQIQNXKCKAJTPF-UHFFFAOYSA-N 50300864 5-methoxy-2-(4-(methylsulfonyl)phenyl)-1H-indole::CHEMBL565567 Prostaglandin G/H synthase 2 Ovis aries 80 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300864&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45484514 104155225 CHEMBL565567 ZINC45245531 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536295 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536297 CS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2ccc3CCCCc3c2n1 InChI=1S/C21H19NO4S/c1-27(25,26)15-9-6-14(7-10-15)19-12-18(21(23)24)17-11-8-13-4-2-3-5-16(13)20(17)22-19/h6-12H,2-5H2,1H3,(H,23,24) JDDCHQYJQPPDNS-UHFFFAOYSA-N 50300865 7,8,9,10-Tetrahydro-2-(4-(methylsulfonyl)phenyl)benzo[h]quinoline-4-carboxylic acid::CHEMBL583020 Prostaglandin G/H synthase 2 Ovis aries 43 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300865&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45484462 104155226 CHEMBL583020 ZINC45316436 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536299 CS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2ccc3ccccc3c2n1 InChI=1S/C21H15NO4S/c1-27(25,26)15-9-6-14(7-10-15)19-12-18(21(23)24)17-11-8-13-4-2-3-5-16(13)20(17)22-19/h2-12H,1H3,(H,23,24) YBLFBBGJHIUGBI-UHFFFAOYSA-N 50300866 2-(4-(Methylsulfonyl)phenyl)benzo[h]quinoline-4-carboxylic acid::CHEMBL568433 Prostaglandin G/H synthase 2 Ovis aries 54 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300866&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45484461 104155227 CHEMBL568433 ZINC45254673 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536301 CS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2cccc(-c3ccccc3)c2n1 InChI=1S/C23H17NO4S/c1-29(27,28)17-12-10-16(11-13-17)21-14-20(23(25)26)19-9-5-8-18(22(19)24-21)15-6-3-2-4-7-15/h2-14H,1H3,(H,25,26) MLQPRQDMBSYVDQ-UHFFFAOYSA-N 50300867 2-(4-(Methylsulfonyl)phenyl)-8-phenyl-quinoline-4-carboxylic acid::CHEMBL576416 Prostaglandin G/H synthase 2 Ovis aries 71 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300867&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45484442 104155228 CHEMBL576416 ZINC45291309 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536303 Cc1ccc2c(cc(nc2c1C)-c1ccc(cc1)S(C)(=O)=O)C(O)=O InChI=1S/C19H17NO4S/c1-11-4-9-15-16(19(21)22)10-17(20-18(15)12(11)2)13-5-7-14(8-6-13)25(3,23)24/h4-10H,1-3H3,(H,21,22) XINSVPZIHDLZSQ-UHFFFAOYSA-N 50300868 7,8-Dimethyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-carboxylic acid::CHEMBL568681 Prostaglandin G/H synthase 2 Ovis aries 75 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300868&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45484428 104155229 CHEMBL568681 ZINC45259530 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536305 Cc1cccc2c(cc(nc12)-c1ccc(cc1)S(C)(=O)=O)C(O)=O InChI=1S/C18H15NO4S/c1-11-4-3-5-14-15(18(20)21)10-16(19-17(11)14)12-6-8-13(9-7-12)24(2,22)23/h3-10H,1-2H3,(H,20,21) GBDGUBHVIYESKW-UHFFFAOYSA-N 50300869 8-Methyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-carboxylic acid::CHEMBL565939 Prostaglandin G/H synthase 2 Ovis aries 86 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300869&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45484427 104155230 CHEMBL565939 ZINC45245434 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50536307 CS(=O)(=O)c1ccc(cc1)-c1cc(C(O)=O)c2ccccc2n1 InChI=1S/C17H13NO4S/c1-23(21,22)12-8-6-11(7-9-12)16-10-14(17(19)20)13-4-2-3-5-15(13)18-16/h2-10H,1H3,(H,19,20) RKFNSQLVEUDBPY-UHFFFAOYSA-N 50300870 2-(4-(methylsulfonyl)phenyl)-quinoline-4-carboxylic acid::CHEMBL579203 Prostaglandin G/H synthase 2 Ovis aries 91 ChEMBL 10.1016/j.bmc.2009.05.084 10.7270/Q2NS0TZX 19560931 Zarghi, A; Ghodsi, R; Azizi, E; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300870&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45484408 104155231 CHEMBL579203 ZINC45303085 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50557112 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1016/j.bmcl.2009.12.073 10.7270/Q22V2G63 20045320 Yu, G; Chowdhury, MA; Abdellatif, KR; Dong, Y; Praveen Rao, PN; Das, D; Velazquez, CA; Suresh, MR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50569793 CS(=O)(=O)Nc1ccc(cc1OC1CCCCC1)[N+]([O-])=O InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 KTDZCOWXCWUPEO-UHFFFAOYSA-N 50029593 CHEMBL7162::N-(2-(cyclohexyloxy)-4-nitrophenyl)methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide(NS-398)::N-[2-(cyclohexyloxy)-4-nitrophenyl]methane sulfonamide::N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulfonamide::N-{2-(cyclohexyloxy)-4-[hydroxy(oxido)amino]phenyl}methanesulfonamide::NS-398::NS398 Prostaglandin G/H synthase 2 Ovis aries 2600 ChEMBL 10.1016/j.bmc.2009.10.031 10.7270/Q2MG7PNG 20236826 Blunder, M; Pferschy-Wenzig, EM; Fabian, WM; Hufner, A; Kunert, O; Saf, R; Schuhly, W; Bauer, R University of Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029593&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NS4 3QMO 4553 103938654 73458 CHEMBL7162 ZINC03791739 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50569794 CC(O)C1(C)Cc2cc(O)c(O)c(O)c2-c2c(C1)cc(O)c(O)c2O InChI=1S/C18H20O7/c1-7(19)18(2)5-8-3-10(20)14(22)16(24)12(8)13-9(6-18)4-11(21)15(23)17(13)25/h3-4,7,19-25H,5-6H2,1-2H3 BOXWNEZQGRBMFD-UHFFFAOYSA-N 50315284 CHEMBL1089510::aR-6,7-Dihydro-6-(10-hydroxyethyl)-6-methyl-5H-dibenzo[a,c]cycloheptene-1,2,3,9,10,11-hexaol Prostaglandin G/H synthase 2 Ovis aries 32100 ChEMBL 10.1016/j.bmc.2009.10.031 10.7270/Q2MG7PNG 20236826 Blunder, M; Pferschy-Wenzig, EM; Fabian, WM; Hufner, A; Kunert, O; Saf, R; Schuhly, W; Bauer, R University of Graz http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50315284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50315284&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46866296 104149645 CHEMBL1089510 ZINC49066972 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575938 CCSC[C@@H]1C[C@](O)(C[C@H](C)O1)c1ccccc1 InChI=1S/C15H22O2S/c1-3-18-11-14-10-15(16,9-12(2)17-14)13-7-5-4-6-8-13/h4-8,12,14,16H,3,9-11H2,1-2H3/t12-,14-,15+/m0/s1 CZONFANKYNQMCS-AEGPPILISA-N 50317917 (2S*,4R*,6S*)-2-((Ethylthio)methyl)tetrahydro-6-methyl-4-phenyl-2H-pyran-4-ol::CHEMBL1096320 Prostaglandin G/H synthase 2 Ovis aries 175 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317917&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46223819 104152278 CHEMBL1096320 ZINC49052513 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575940 C[C@H]1C[C@@](O)(C[C@@H](CSC#N)O1)c1ccccc1 InChI=1S/C14H17NO2S/c1-11-7-14(16,12-5-3-2-4-6-12)8-13(17-11)9-18-10-15/h2-6,11,13,16H,7-9H2,1H3/t11-,13-,14+/m0/s1 XZRWEDLKBUWJEV-FPMFFAJLSA-N 50317918 (2S*,4R*,6S*)-Tetrahydro-2-methyl-4-phenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1096383 Prostaglandin G/H synthase 2 Ovis aries 117 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317918&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46223820 104152279 CHEMBL1096383 ZINC49781462 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575942 CCSC[C@@H]1C[C@](O)(C[C@@H](O1)c1ccccc1)c1ccccc1 InChI=1S/C20H24O2S/c1-2-23-15-18-13-20(21,17-11-7-4-8-12-17)14-19(22-18)16-9-5-3-6-10-16/h3-12,18-19,21H,2,13-15H2,1H3/t18-,19+,20-/m0/s1 BVUBEKFQTZZYPI-ZCNNSNEGSA-N 50317919 (2S*,4R*,6R*)-2-((Ethylthio)methyl)tetrahydro-4,6-diphenyl-2H-pyran-4-ol::CHEMBL1096384 Prostaglandin G/H synthase 2 Ovis aries 2.07 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317919&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46224069 104152280 CHEMBL1096384 ZINC49111957 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575944 O[C@]1(C[C@@H](CSC#N)O[C@H](C1)c1ccccc1)c1ccccc1 InChI=1S/C19H19NO2S/c20-14-23-13-17-11-19(21,16-9-5-2-6-10-16)12-18(22-17)15-7-3-1-4-8-15/h1-10,17-18,21H,11-13H2/t17-,18+,19-/m0/s1 WIEIKACUUNKAQD-OTWHNJEPSA-N 50317920 (2R*,4R*,6S*)-Tetrahydro-2,4-diphenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1096036 Prostaglandin G/H synthase 2 Ovis aries 1.47 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317920&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46224070 104152281 CHEMBL1096036 ZINC49112653 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575946 CCSC[C@@H]1C[C@](O)(C[C@@H](O1)c1ccc(F)cc1)c1ccccc1 InChI=1S/C20H23FO2S/c1-2-24-14-18-12-20(22,16-6-4-3-5-7-16)13-19(23-18)15-8-10-17(21)11-9-15/h3-11,18-19,22H,2,12-14H2,1H3/t18-,19+,20-/m0/s1 CBOPNSRBBJCEGV-ZCNNSNEGSA-N 50317921 (2S*,4R*,6R*)-2-((Ethylthio)methyl)-6-(4-fluorophenyl)tetrahydro-4-phenyl-2H-pyran-4-ol::CHEMBL1096037 Prostaglandin G/H synthase 2 Ovis aries 2.05 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317921&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46224071 104152282 CHEMBL1096037 ZINC49784971 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575948 O[C@]1(C[C@@H](CSC#N)O[C@H](C1)c1ccc(F)cc1)c1ccccc1 InChI=1S/C19H18FNO2S/c20-16-8-6-14(7-9-16)18-11-19(22,15-4-2-1-3-5-15)10-17(23-18)12-24-13-21/h1-9,17-18,22H,10-12H2/t17-,18+,19-/m0/s1 WAMFUOJWQQDDMD-OTWHNJEPSA-N 50317922 (2R*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-4-phenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1096385 Prostaglandin G/H synthase 2 Ovis aries 3.57 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317922&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46224072 104152283 CHEMBL1096385 ZINC49783677 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575950 CCSC[C@@H]1C[C@](O)(C[C@@H](O1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C20H23ClO2S/c1-2-24-14-18-12-20(22,16-6-4-3-5-7-16)13-19(23-18)15-8-10-17(21)11-9-15/h3-11,18-19,22H,2,12-14H2,1H3/t18-,19+,20-/m0/s1 FPGNAQGJVPLCGL-ZCNNSNEGSA-N 50317923 (2R*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)methyl)tetrahydro-4-phenyl-2H-pyran-4-ol::CHEMBL1095082 Prostaglandin G/H synthase 2 Ovis aries 1.82 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317923&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46224073 104152284 CHEMBL1095082 ZINC49070729 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575952 O[C@]1(C[C@@H](CSC#N)O[C@H](C1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C19H18ClNO2S/c20-16-8-6-14(7-9-16)18-11-19(22,15-4-2-1-3-5-15)10-17(23-18)12-24-13-21/h1-9,17-18,22H,10-12H2/t17-,18+,19-/m0/s1 FZAPPHMXVLWNFB-OTWHNJEPSA-N 50317924 (2R*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-4-phenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1095083 Prostaglandin G/H synthase 2 Ovis aries 0.9 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317924&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46224074 104152285 CHEMBL1095083 ZINC49070730 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575954 CCSC[C@@H]1C[C@](O)(C[C@@H](O1)c1ccc(Br)cc1)c1ccccc1 InChI=1S/C20H23BrO2S/c1-2-24-14-18-12-20(22,16-6-4-3-5-7-16)13-19(23-18)15-8-10-17(21)11-9-15/h3-11,18-19,22H,2,12-14H2,1H3/t18-,19+,20-/m0/s1 ZEBVEZWCKJNDFY-ZCNNSNEGSA-N 50317925 (2R*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)methyl)tetrahydro-4-phenyl-2H-pyran-4-ol::CHEMBL1095084 Prostaglandin G/H synthase 2 Ovis aries 5.49 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317925&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46224075 104152286 CHEMBL1095084 ZINC49068768 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575956 O[C@]1(C[C@@H](CSC#N)O[C@H](C1)c1ccc(Br)cc1)c1ccccc1 InChI=1S/C19H18BrNO2S/c20-16-8-6-14(7-9-16)18-11-19(22,15-4-2-1-3-5-15)10-17(23-18)12-24-13-21/h1-9,17-18,22H,10-12H2/t17-,18+,19-/m0/s1 PBQRRRNLLBVHCJ-OTWHNJEPSA-N 50317926 (2R*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-4-phenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1094096 Prostaglandin G/H synthase 2 Ovis aries 4.01 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317926&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220727 104152287 CHEMBL1094096 ZINC49112390 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575958 CCSC[C@@H]1C[C@@](O)([C@H]([C@@H](O1)c1ccccc1)c1ccccc1)c1ccccc1 InChI=1S/C26H28O2S/c1-2-29-19-23-18-26(27,22-16-10-5-11-17-22)24(20-12-6-3-7-13-20)25(28-23)21-14-8-4-9-15-21/h3-17,23-25,27H,2,18-19H2,1H3/t23-,24-,25-,26-/m0/s1 UPTSZZUOIGQJNC-CQJMVLFOSA-N 50317927 (2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)tetrahydro-2,3,4-triphenyl-2H-pyran-4-ol::CHEMBL1094097 Prostaglandin G/H synthase 2 Ovis aries 1.72 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317927&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220728 104152288 CHEMBL1094097 ZINC49072496 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575960 O[C@@]1(C[C@@H](CSC#N)O[C@H]([C@@H]1c1ccccc1)c1ccccc1)c1ccccc1 InChI=1S/C25H23NO2S/c26-18-29-17-22-16-25(27,21-14-8-3-9-15-21)23(19-10-4-1-5-11-19)24(28-22)20-12-6-2-7-13-20/h1-15,22-24,27H,16-17H2/t22-,23-,24-,25-/m0/s1 ASFZJMRECGOZIJ-QORCZRPOSA-N 50317928 (2R*,3S*,4R*,6S*)-Tetrahydro-2,3,4-triphenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1094412 Prostaglandin G/H synthase 2 Ovis aries 1.55 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317928&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220729 104152289 CHEMBL1094412 ZINC49115292 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575962 CCSC[C@@H]1C[C@@](O)([C@H]([C@@H](O1)c1ccc(F)cc1)c1ccccc1)c1ccccc1 InChI=1S/C26H27FO2S/c1-2-30-18-23-17-26(28,21-11-7-4-8-12-21)24(19-9-5-3-6-10-19)25(29-23)20-13-15-22(27)16-14-20/h3-16,23-25,28H,2,17-18H2,1H3/t23-,24-,25-,26-/m0/s1 FSXDGPMVZPSKCM-CQJMVLFOSA-N 50317929 (2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)-2-(4-fluorophenyl)-tetrahydro-3,4-diphenyl-2H-pyran-4-ol::CHEMBL1094413 Prostaglandin G/H synthase 2 Ovis aries 1.28 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317929&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220730 104152290 CHEMBL1094413 ZINC49073192 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575964 O[C@@]1(C[C@@H](CSC#N)O[C@H]([C@@H]1c1ccccc1)c1ccc(F)cc1)c1ccccc1 InChI=1S/C25H22FNO2S/c26-21-13-11-19(12-14-21)24-23(18-7-3-1-4-8-18)25(28,20-9-5-2-6-10-20)15-22(29-24)16-30-17-27/h1-14,22-24,28H,15-16H2/t22-,23-,24-,25-/m0/s1 LKLSPOXUXUIYBW-QORCZRPOSA-N 50317930 (2R*,3S*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-3,4-diphenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1098066 Prostaglandin G/H synthase 2 Ovis aries 1.11 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317930&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220731 104152291 CHEMBL1098066 ZINC49115120 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575966 CCSC[C@@H]1C[C@@](O)([C@H]([C@@H](O1)c1ccc(Cl)cc1)c1ccccc1)c1ccccc1 InChI=1S/C26H27ClO2S/c1-2-30-18-23-17-26(28,21-11-7-4-8-12-21)24(19-9-5-3-6-10-19)25(29-23)20-13-15-22(27)16-14-20/h3-16,23-25,28H,2,17-18H2,1H3/t23-,24-,25-,26-/m0/s1 SSSTXMLNHBBEBR-CQJMVLFOSA-N 50317931 (2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)methyl)-tetrahydro-3,4-diphenyl-2H-pyran-4-ol::CHEMBL1096723 Prostaglandin G/H synthase 2 Ovis aries 0.57 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317931&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220732 104152292 CHEMBL1096723 ZINC49114751 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575968 O[C@@]1(C[C@@H](CSC#N)O[C@H]([C@@H]1c1ccccc1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C25H22ClNO2S/c26-21-13-11-19(12-14-21)24-23(18-7-3-1-4-8-18)25(28,20-9-5-2-6-10-20)15-22(29-24)16-30-17-27/h1-14,22-24,28H,15-16H2/t22-,23-,24-,25-/m0/s1 XTFRSVRWDKFVGA-QORCZRPOSA-N 50317932 (2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-3,4-diphenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1096724 Prostaglandin G/H synthase 2 Ovis aries 0.65 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317932&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220944 104152293 CHEMBL1096724 ZINC49784235 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575970 CCSC[C@@H]1C[C@@](O)([C@H]([C@@H](O1)c1ccc(Br)cc1)c1ccccc1)c1ccccc1 InChI=1S/C26H27BrO2S/c1-2-30-18-23-17-26(28,21-11-7-4-8-12-21)24(19-9-5-3-6-10-19)25(29-23)20-13-15-22(27)16-14-20/h3-16,23-25,28H,2,17-18H2,1H3/t23-,24-,25-,26-/m0/s1 GJKDCSBFEHBUOJ-CQJMVLFOSA-N 50317933 (2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)methyl)-tetrahydro-3,4-diphenyl-2H-pyran-4-ol)::CHEMBL1096725 Prostaglandin G/H synthase 2 Ovis aries 2.8 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317933&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220945 104152294 CHEMBL1096725 ZINC49784236 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575972 O[C@@]1(C[C@@H](CSC#N)O[C@H]([C@@H]1c1ccccc1)c1ccc(Br)cc1)c1ccccc1 InChI=1S/C25H22BrNO2S/c26-21-13-11-19(12-14-21)24-23(18-7-3-1-4-8-18)25(28,20-9-5-2-6-10-20)15-22(29-24)16-30-17-27/h1-14,22-24,28H,15-16H2/t22-,23-,24-,25-/m0/s1 VAARSVSQTNZNIE-QORCZRPOSA-N 50317934 (2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-3,4-diphenyl-6-(thiocyanatomethyl)-2H-pyran-4-ol::CHEMBL1095094 Prostaglandin G/H synthase 2 Ovis aries 4.03 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317934&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46220946 104152295 CHEMBL1095094 ZINC49111183 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575974 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50575976 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1021/jm1001327 10.7270/Q2NP24KF 20387815 Singh, P; Bhardwaj, A Guru Nanak Dev University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598098 CS(=O)(=O)c1ccc(cc1)C(=O)C(=C\c1ccccc1)\c1ccccc1 InChI=1S/C22H18O3S/c1-26(24,25)20-14-12-19(13-15-20)22(23)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-16H,1H3/b21-16+ QAAXGHXQLIVPJE-LTGZKZEYSA-N 50326308 (E)-1-(4-(Methylsulfonyl)phenyl)-2,3-diphenylprop-2-en-1-one::CHEMBL1243082 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326308&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46933946 123105423 CHEMBL1243082 ZINC64532150 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598099 CS(=O)(=O)c1ccc(cc1)C(=O)C(=C/c1ccccc1)\c1ccccc1 InChI=1S/C22H18O3S/c1-26(24,25)20-14-12-19(13-15-20)22(23)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17/h2-16H,1H3/b21-16- QAAXGHXQLIVPJE-PGMHBOJBSA-N 50326309 (Z)-1-(4-(Methylsulfonyl)phenyl)-2,3-diphenylprop-2-en-1-one::CHEMBL1243083 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326309&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934094 123105424 CHEMBL1243083 ZINC64553425 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598100 CS(=O)(=O)c1ccc(cc1)C(=O)C(=C\c1ccc(F)cc1)\c1ccccc1 InChI=1S/C22H17FO3S/c1-27(25,26)20-13-9-18(10-14-20)22(24)21(17-5-3-2-4-6-17)15-16-7-11-19(23)12-8-16/h2-15H,1H3/b21-15+ BGECTZFWNCWETG-RCCKNPSSSA-N 50326310 (E)-3-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-2-phenylprop-2-en-1-one::CHEMBL1243118 Prostaglandin G/H synthase 2 Ovis aries 190 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326310&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934095 123105425 CHEMBL1243118 ZINC64553907 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598101 CS(=O)(=O)c1ccc(cc1)C(=O)C(=C/c1ccc(F)cc1)\c1ccccc1 InChI=1S/C22H17FO3S/c1-27(25,26)20-13-9-18(10-14-20)22(24)21(17-5-3-2-4-6-17)15-16-7-11-19(23)12-8-16/h2-15H,1H3/b21-15- BGECTZFWNCWETG-QNGOZBTKSA-N 50326311 (Z)-3-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-2-phenylprop-2-en-1-one::CHEMBL1243119 Prostaglandin G/H synthase 2 Ovis aries 160 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326311&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934096 123105426 CHEMBL1243119 ZINC64553780 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598102 Cc1ccc(\C=C(\C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc2)cc1 InChI=1S/C23H20O3S/c1-17-8-10-18(11-9-17)16-22(19-6-4-3-5-7-19)23(24)20-12-14-21(15-13-20)27(2,25)26/h3-16H,1-2H3/b22-16+ JIUDLNXREYFIAA-CJLVFECKSA-N 50326312 (E)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-p-tolylprop-2-en-1-one::CHEMBL1243145 Prostaglandin G/H synthase 2 Ovis aries 280 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326312&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934097 123105427 CHEMBL1243145 ZINC64564909 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598103 Cc1ccc(\C=C(/C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc2)cc1 InChI=1S/C23H20O3S/c1-17-8-10-18(11-9-17)16-22(19-6-4-3-5-7-19)23(24)20-12-14-21(15-13-20)27(2,25)26/h3-16H,1-2H3/b22-16- JIUDLNXREYFIAA-JWGURIENSA-N 50326313 (Z)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-p-tolylprop-2-en-1-one::CHEMBL1243146 Prostaglandin G/H synthase 2 Ovis aries 210 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326313&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934098 123105428 CHEMBL1243146 ZINC64479820 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598104 COc1ccc(\C=C(\C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc2)cc1 InChI=1S/C23H20O4S/c1-27-20-12-8-17(9-13-20)16-22(18-6-4-3-5-7-18)23(24)19-10-14-21(15-11-19)28(2,25)26/h3-16H,1-2H3/b22-16+ PSPGWQBSEPDIST-CJLVFECKSA-N 50326314 (E)-3-(4-Methoxyphenyl)-1-(4-(methylsulfonyl)phenyl)-2-phenylprop-2-en-1-one::CHEMBL1243176 Prostaglandin G/H synthase 2 Ovis aries 220 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326314&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934099 123105429 CHEMBL1243176 ZINC64564701 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598105 COc1ccc(\C=C(/C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc2)cc1 InChI=1S/C23H20O4S/c1-27-20-12-8-17(9-13-20)16-22(18-6-4-3-5-7-18)23(24)19-10-14-21(15-11-19)28(2,25)26/h3-16H,1-2H3/b22-16- PSPGWQBSEPDIST-JWGURIENSA-N 50326315 (Z)-3-(4-Methoxyphenyl)-1-(4-(methylsulfonyl)phenyl)-2-phenylprop-2-en-1-one::CHEMBL1243177 Prostaglandin G/H synthase 2 Ovis aries 210 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326315&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934100 123105430 CHEMBL1243177 ZINC64454247 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598106 CS(=O)(=O)c1ccc(cc1)C(=O)C(=C\c1ccc(O)cc1)\c1ccccc1 InChI=1S/C22H18O4S/c1-27(25,26)20-13-9-18(10-14-20)22(24)21(17-5-3-2-4-6-17)15-16-7-11-19(23)12-8-16/h2-15,23H,1H3/b21-15+ HEUSNEARDHIKKU-RCCKNPSSSA-N 50326316 (E)-3-(4-Hydroxyphenyl)-1-(4-(methylsulfonyl)phenyl)-2-phenylprop-2-en-1-one::CHEMBL1243209 Prostaglandin G/H synthase 2 Ovis aries 80 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326316&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46933944 123105431 CHEMBL1243209 ZINC64564740 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598107 CS(=O)(=O)c1ccc(cc1)C(=O)C(=C\c1cccs1)\c1ccccc1 InChI=1S/C20H16O3S2/c1-25(22,23)18-11-9-16(10-12-18)20(21)19(14-17-8-5-13-24-17)15-6-3-2-4-7-15/h2-14H,1H3/b19-14+ AKODJYWXZQXLMX-XMHGGMMESA-N 50326317 (E)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-(thiophen-2-yl)prop-2-en-1-one::CHEMBL1243210 Prostaglandin G/H synthase 2 Ovis aries 130 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326317&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934235 123105432 CHEMBL1243210 ZINC64574068 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598108 CS(=O)(=O)c1ccc(cc1)C(=O)C(=Cc1ccncc1)c1ccccc1 InChI=1S/C21H17NO3S/c1-26(24,25)19-9-7-18(8-10-19)21(23)20(17-5-3-2-4-6-17)15-16-11-13-22-14-12-16/h2-15H,1H3 QGVVRVXIAQZHAX-UHFFFAOYSA-N 50326318 (E/Z)-1-(4-(Methylsulfonyl)phenyl)-2-phenyl-3-(pyridin-4-yl)prop-2-en-1-one::CHEMBL1243242 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326318&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46933945 123105433 CHEMBL1243242 ZINC64479847 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598109 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.ejmech.2010.05.058 10.7270/Q2G1612W 20691338 Arfaie, S; Zarghi, A Shahid Beheshti University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50600300 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 5700 ChEMBL 10.1016/j.bmcl.2010.07.132 10.7270/Q2765FJ9 20727750 Chowdhury, MA; Huang, Z; Abdellatif, KR; Dong, Y; Yu, G; Velazquez, CA; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598558 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 780 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598559 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598560 CC(C)Cc1ccc(cc1)[C@H](C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m0/s1 HEFNNWSXXWATRW-JTQLQIEISA-N 50169047 (S)-2-(4-Isobutyl-phenyl)-propionic acid::(S)-2-(4-isobutylphenyl)propanoic acid::(S)-ibuprofen::CHEMBL175::DEXIBUPROFEN::IBUPROFEN LYSINE Prostaglandin G/H synthase 2 Ovis aries 1500 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50169047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50169047&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 39912 104053911 5855 CHEMBL175 DB09213 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598561 CS(=O)(=O)Nc1ccc(cc1OC1CCCCC1)[N+]([O-])=O InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 KTDZCOWXCWUPEO-UHFFFAOYSA-N 50029593 CHEMBL7162::N-(2-(cyclohexyloxy)-4-nitrophenyl)methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide(NS-398)::N-[2-(cyclohexyloxy)-4-nitrophenyl]methane sulfonamide::N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulfonamide::N-{2-(cyclohexyloxy)-4-[hydroxy(oxido)amino]phenyl}methanesulfonamide::NS-398::NS398 Prostaglandin G/H synthase 2 Ovis aries 73200 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029593&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NS4 3QMO 4553 103938654 73458 CHEMBL7162 ZINC03791739 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598562 CS(=O)(=O)c1ccc(cc1)-n1ccc2ccccc12 InChI=1S/C15H13NO2S/c1-19(17,18)14-8-6-13(7-9-14)16-11-10-12-4-2-3-5-15(12)16/h2-11H,1H3 XRGCFRFZQVGLLT-UHFFFAOYSA-N 50326520 1-(4-(methylsulfonyl)phenyl)-1H-indole::CHEMBL1240964 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326520&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11958319 123105635 CHEMBL1240964 ZINC64475267 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598563 CS(=O)(=O)c1ccc(cc1)-n1cccc1 InChI=1S/C11H11NO2S/c1-15(13,14)11-6-4-10(5-7-11)12-8-2-3-9-12/h2-9H,1H3 NIVLUABJSRHBFE-UHFFFAOYSA-N 50326521 1-(4-(methylsulfonyl)phenyl)-1H-pyrrole::CHEMBL1240963 Prostaglandin G/H synthase 2 Ovis aries 8500 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326521&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 22316981 123105636 CHEMBL1240963 ZINC35120168 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598564 CS(=O)(=O)c1ccc(cc1)N1CCN(CC1)c1ccc(F)cc1 InChI=1S/C17H19FN2O2S/c1-23(21,22)17-8-6-16(7-9-17)20-12-10-19(11-13-20)15-4-2-14(18)3-5-15/h2-9H,10-13H2,1H3 JUBVJXZAZSUNAT-UHFFFAOYSA-N 50326522 1-(4-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)piperazine::CHEMBL1243100 Prostaglandin G/H synthase 2 Ovis aries 18800 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326522&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 52943220 123105637 CHEMBL1243100 ZINC64485510 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598565 CS(=O)(=O)c1ccc(Nc2ccc(F)cc2)cc1 InChI=1S/C13H12FNO2S/c1-18(16,17)13-8-6-12(7-9-13)15-11-4-2-10(14)3-5-11/h2-9,15H,1H3 QTRCGPBYCSHGJM-UHFFFAOYSA-N 50326523 4-fluoro-N-(4-(methylsulfonyl)phenyl)aniline::CHEMBL1240925 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326523&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46937407 123105638 CHEMBL1240925 ZINC64479826 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598566 CS(=O)(=O)c1ccc(cc1)C1Oc2ccccc2-n2cccc12 InChI=1S/C18H15NO3S/c1-23(20,21)14-10-8-13(9-11-14)18-16-6-4-12-19(16)15-5-2-3-7-17(15)22-18/h2-12,18H,1H3 SFTNUIFOMNGJMA-UHFFFAOYSA-N 50326524 4-(4-(methylsulfonyl)phenyl)-4H-benzo[b]pyrrolo[1,2-d][1,4]oxazine::CHEMBL1243099 Prostaglandin G/H synthase 2 Ovis aries 26500 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326524&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46938389 123105639 CHEMBL1243099 ZINC64532198 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598567 CS(=O)(=O)c1ccc(cc1)-c1ccccn1 InChI=1S/C12H11NO2S/c1-16(14,15)11-7-5-10(6-8-11)12-4-2-3-9-13-12/h2-9H,1H3 PCRZBBOIGHSIEX-UHFFFAOYSA-N 50326525 2-(4-(methylsulfonyl)phenyl)pyridine::CHEMBL1240924 Prostaglandin G/H synthase 2 Ovis aries 1300 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326525&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46937403 123105640 CHEMBL1240924 ZINC64479744 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598568 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccc(F)cc1 InChI=1S/C14H11FO3S/c1-19(17,18)13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3 HYUDUBGICRHDPP-UHFFFAOYSA-N 50326526 (4-fluorophenyl)(4-(methylsulfonyl)phenyl)methanone::CHEMBL1240923 Prostaglandin G/H synthase 2 Ovis aries 7700 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326526&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10107581 123105641 CHEMBL1240923 ZINC34220290 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598569 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccc(Br)cc1 InChI=1S/C14H11BrO3S/c1-19(17,18)13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3 MDJBMCZZYBLPTR-UHFFFAOYSA-N 50326527 (4-bromophenyl)(4-(methylsulfonyl)phenyl)methanone::CHEMBL1240922 Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326527&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 21262853 123105642 CHEMBL1240922 ZINC36941786 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598570 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccsc1 InChI=1S/C12H10O3S2/c1-17(14,15)11-4-2-9(3-5-11)12(13)10-6-7-16-8-10/h2-8H,1H3 UINJFISXUJQXRO-UHFFFAOYSA-N 50326528 (4-(methylsulfonyl)phenyl)(thiophen-3-yl)methanone::CHEMBL1240889 Prostaglandin G/H synthase 2 Ovis aries 15200 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326528&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46938387 123105643 CHEMBL1240889 ZINC64490659 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598571 CS(=O)(=O)c1ccc(cc1)C(=O)c1cccs1 InChI=1S/C12H10O3S2/c1-17(14,15)10-6-4-9(5-7-10)12(13)11-3-2-8-16-11/h2-8H,1H3 XYKMPECPWAFYIN-UHFFFAOYSA-N 50326529 2-(p-Methylsulfonylbenzoyl)thiophene::CHEMBL1240888 Prostaglandin G/H synthase 2 Ovis aries 23100 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326529&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 21262955 123105644 CHEMBL1240888 ZINC34976754 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598572 CS(=O)(=O)c1ccc(cc1)C(=O)c1c[nH]c2ccccc12 InChI=1S/C16H13NO3S/c1-21(19,20)12-8-6-11(7-9-12)16(18)14-10-17-15-5-3-2-4-13(14)15/h2-10,17H,1H3 RKEQYMMBIKIYDW-UHFFFAOYSA-N 50326530 (1H-indol-3-yl)(4-(methylsulfonyl)phenyl)methanone::CHEMBL1243098 Prostaglandin G/H synthase 2 Ovis aries 9400 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326530&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 43339272 123105645 CHEMBL1243098 ZINC37361506 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598573 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccn(c1)-c1ccccc1F InChI=1S/C18H14FNO3S/c1-24(22,23)15-8-6-13(7-9-15)18(21)14-10-11-20(12-14)17-5-3-2-4-16(17)19/h2-12H,1H3 DAUXFNDEYXUIPZ-UHFFFAOYSA-N 50326531 (1-(2-fluorophenyl)-1H-pyrrol-3-yl)(4-(methylsulfonyl)phenyl)methanone::CHEMBL1243067 Prostaglandin G/H synthase 2 Ovis aries 19700 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326531&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46939840 123105646 CHEMBL1243067 ZINC64479799 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50593625 Cn1c2ccc(cc2oc1=O)-c1cc(nn1-c1ccc(F)cc1)C(F)(F)F InChI=1S/C18H11F4N3O2/c1-24-13-7-2-10(8-15(13)27-17(24)26)14-9-16(18(20,21)22)23-25(14)12-5-3-11(19)4-6-12/h2-9H,1H3 YKOUXSMVMVBXAV-UHFFFAOYSA-N 50325643 1-(4-Fluorophenyl)-3-trifluoromethyl-5-(3-methyl-2-oxo-3H-benzoxazole-6-yl)-1H-pyrazole::CHEMBL1224099 Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.1016/j.bmc.2010.07.009 10.7270/Q2VH5P15 20692174 Eren, G; Unlu, S; Nunez, MT; Labeaga, L; Ledo, F; Entrena, A; Banoglu, E; Costantino, G; Sahin, MF Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325643&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 49865883 117646964 CHEMBL1224099 ZINC58590915 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50593626 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 537 ChEMBL 10.1016/j.bmc.2010.07.009 10.7270/Q2VH5P15 20692174 Eren, G; Unlu, S; Nunez, MT; Labeaga, L; Ledo, F; Entrena, A; Banoglu, E; Costantino, G; Sahin, MF Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50593627 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 398 ChEMBL 10.1016/j.bmc.2010.07.009 10.7270/Q2VH5P15 20692174 Eren, G; Unlu, S; Nunez, MT; Labeaga, L; Ledo, F; Entrena, A; Banoglu, E; Costantino, G; Sahin, MF Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50593628 COc1ccc(cc1)C1=C(COC1=O)c1ccc2n(C)c(=O)oc2c1 InChI=1S/C19H15NO5/c1-20-15-8-5-12(9-16(15)25-19(20)22)14-10-24-18(21)17(14)11-3-6-13(23-2)7-4-11/h3-9H,10H2,1-2H3 DDGISTTYWXJFQT-UHFFFAOYSA-N 50325645 3-(4-Methoxyphenyl)-4-(3-methyl-2-oxo-3H-benzoxazole-6-yl)-2-oxo-5H-furane::CHEMBL1223901 Prostaglandin G/H synthase 2 Ovis aries 325 ChEMBL 10.1016/j.bmc.2010.07.009 10.7270/Q2VH5P15 20692174 Eren, G; Unlu, S; Nunez, MT; Labeaga, L; Ledo, F; Entrena, A; Banoglu, E; Costantino, G; Sahin, MF Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325645&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934725 117646966 CHEMBL1223901 ZINC58581333 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50593631 Cn1c2ccc(cc2oc1=O)-c1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F InChI=1S/C18H11ClF3N3O2/c1-24-13-7-2-10(8-15(13)27-17(24)26)14-9-16(18(20,21)22)23-25(14)12-5-3-11(19)4-6-12/h2-9H,1H3 WDIGEJBRJMLFMX-UHFFFAOYSA-N 50325644 1-(4-Chlorophenyl)-3-trifluoromethyl-5-(3-methyl-2-oxo-3H-benzoxazole-6-yl)-1H-pyrazole::CHEMBL1224098 Prostaglandin G/H synthase 2 Ovis aries 11 ChEMBL 10.1016/j.bmc.2010.07.009 10.7270/Q2VH5P15 20692174 Eren, G; Unlu, S; Nunez, MT; Labeaga, L; Ledo, F; Entrena, A; Banoglu, E; Costantino, G; Sahin, MF Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325644&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46912219 117646965 CHEMBL1224098 ZINC58591384 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50593632 COc1ccc(cc1)-n1nc(cc1-c1ccc2n(C)c(=O)oc2c1)C(F)(F)F InChI=1S/C19H14F3N3O3/c1-24-14-8-3-11(9-16(14)28-18(24)26)15-10-17(19(20,21)22)23-25(15)12-4-6-13(27-2)7-5-12/h3-10H,1-2H3 XAXSEOKNXMOLKL-UHFFFAOYSA-N 50325646 1-(4-Methoxyphenyl)-3-trifluoromethyl-5-(3-methyl-2-oxo-3H-benzoxazole-6-yl)-1H-pyrazole::CHEMBL1224097 Prostaglandin G/H synthase 2 Ovis aries 11 ChEMBL 10.1016/j.bmc.2010.07.009 10.7270/Q2VH5P15 20692174 Eren, G; Unlu, S; Nunez, MT; Labeaga, L; Ledo, F; Entrena, A; Banoglu, E; Costantino, G; Sahin, MF Gazi University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325646&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46934868 117646967 CHEMBL1224097 ZINC58581450 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598574 CS(=O)(=O)c1ccc(cc1)C(=O)c1cccn1-c1ccccc1F InChI=1S/C18H14FNO3S/c1-24(22,23)14-10-8-13(9-11-14)18(21)17-7-4-12-20(17)16-6-3-2-5-15(16)19/h2-12H,1H3 HDAZWIGBPLCLOR-UHFFFAOYSA-N 50326532 (1-(2-fluorophenyl)-1H-pyrrol-2-yl)(4-(methylsulfonyl)phenyl)methanone::CHEMBL1243066 Prostaglandin G/H synthase 2 Ovis aries 43300 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326532&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46939839 123105647 CHEMBL1243066 ZINC64564565 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598575 Cn1cc(C(=O)c2ccc(cc2)S(C)(=O)=O)c2ccccc12 InChI=1S/C17H15NO3S/c1-18-11-15(14-5-3-4-6-16(14)18)17(19)12-7-9-13(10-8-12)22(2,20)21/h3-11H,1-2H3 FOEUPKDQBBKJIV-UHFFFAOYSA-N 50326533 (1-methyl-1H-indol-3-yl)(4-(methylsulfonyl)phenyl)methanone::CHEMBL1243065 Prostaglandin G/H synthase 2 Ovis aries 36800 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326533&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46939838 123105648 CHEMBL1243065 ZINC64574035 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598576 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccoc1 InChI=1S/C12H10O4S/c1-17(14,15)11-4-2-9(3-5-11)12(13)10-6-7-16-8-10/h2-8H,1H3 ULFFSZMVURLRPK-UHFFFAOYSA-N 50326534 CHEMBL1240537::furan-3-yl(4-(methylsulfonyl)phenyl)methanone Prostaglandin G/H synthase 2 Ovis aries 4100 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326534&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46939837 123105649 CHEMBL1240537 ZINC64490658 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50598577 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccco1 InChI=1S/C12H10O4S/c1-17(14,15)10-6-4-9(5-7-10)12(13)11-3-2-8-16-11/h2-8H,1H3 CWRZECMEZICAFW-UHFFFAOYSA-N 50326535 2-(p-Methylsulfonylbenzoyl)furan::CHEMBL1240887 Prostaglandin G/H synthase 2 Ovis aries 19200 ChEMBL 10.1021/jm100398z 10.7270/Q21R6QQW 20804197 Harrak, Y; Casula, G; Basset, J; Rosell, G; Plescia, S; Raffa, D; Cusimano, MG; Pouplana, R; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326535&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 12701751 123105650 CHEMBL1240887 ZINC39270244 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627629 COC1(CCOCC1)c1cccc(CS(=O)(=O)Nc2ccccc2OCc2ccccc2)c1 InChI=1S/C26H29NO5S/c1-30-26(14-16-31-17-15-26)23-11-7-10-22(18-23)20-33(28,29)27-24-12-5-6-13-25(24)32-19-21-8-3-2-4-9-21/h2-13,18,27H,14-17,19-20H2,1H3 HKPIWFACSRKLEV-UHFFFAOYSA-N 50338754 CHEMBL1684380::N-(2-(Benzyloxy)phenyl)-1-(3-(4-methoxytetrahydro-2H-pyran-4-yl)phenyl)methanesulfonamide Prostaglandin G/H synthase 2 Ovis aries 2300 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338754&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53322158 125088856 CHEMBL1684380 ZINC66078730 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627630 COC1(CCOCC1)c1cccc(CS(=O)(=O)Nc2ccc(Cl)cc2OCc2ccccc2)c1 InChI=1S/C26H28ClNO5S/c1-31-26(12-14-32-15-13-26)22-9-5-8-21(16-22)19-34(29,30)28-24-11-10-23(27)17-25(24)33-18-20-6-3-2-4-7-20/h2-11,16-17,28H,12-15,18-19H2,1H3 XMFVNJNIFLJNSM-UHFFFAOYSA-N 50338755 CHEMBL1684381::N-(2-(Benzyloxy)-4-chlorophenyl)-1-(3-(4-methoxytetrahydro-2H-pyran-4-yl)phenyl)methane-sulfonamide Prostaglandin G/H synthase 2 Ovis aries 3700 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338755&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53320298 125088857 CHEMBL1684381 ZINC66078731 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627631 COC1(CCOCC1)c1cccc(CS(=O)(=O)Nc2cc(Cl)ccc2OCc2ccccc2)c1 InChI=1S/C26H28ClNO5S/c1-31-26(12-14-32-15-13-26)22-9-5-8-21(16-22)19-34(29,30)28-24-17-23(27)10-11-25(24)33-18-20-6-3-2-4-7-20/h2-11,16-17,28H,12-15,18-19H2,1H3 CJNKIYYDXORXNP-UHFFFAOYSA-N 50338756 CHEMBL1684382::N-(2-(Benzyloxy)-5-chlorophenyl)-1-(3-(4-methoxytetrahydro-2H-pyran-4-yl)phenyl)methane-sulfonamide Prostaglandin G/H synthase 2 Ovis aries 2900 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338756&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53326086 125088858 CHEMBL1684382 ZINC66102933 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627632 COC1(CCOCC1)c1cccc(CS(=O)(=O)Nc2cc(C)ccc2OCc2ccccc2)c1 InChI=1S/C27H31NO5S/c1-21-11-12-26(33-19-22-7-4-3-5-8-22)25(17-21)28-34(29,30)20-23-9-6-10-24(18-23)27(31-2)13-15-32-16-14-27/h3-12,17-18,28H,13-16,19-20H2,1-2H3 NUXWSNCIGDLGKG-UHFFFAOYSA-N 50338757 CHEMBL1684383::N-(2-(Benzyloxy)-5-methylphenyl)-1-(3-(4-methoxytetrahydro-2H-pyran-4-yl)phenyl)methane-sulfonamide Prostaglandin G/H synthase 2 Ovis aries 4900 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338757&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53324232 125088859 CHEMBL1684383 ZINC66102936 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627633 COC1(CCOCC1)c1cccc(CS(=O)(=O)Nc2ccc(cc2OCc2ccccc2)[N+]([O-])=O)c1 InChI=1S/C26H28N2O7S/c1-33-26(12-14-34-15-13-26)22-9-5-8-21(16-22)19-36(31,32)27-24-11-10-23(28(29)30)17-25(24)35-18-20-6-3-2-4-7-20/h2-11,16-17,27H,12-15,18-19H2,1H3 CGKQOPCAOCOGDW-UHFFFAOYSA-N 50338758 CHEMBL1684384::N-(2-(benzyloxy)-4-nitrophenyl)-1-(3-(4-methoxytetrahydro-2H-pyran-4-yl)phenyl)methanesulfonamide Prostaglandin G/H synthase 2 Ovis aries 1500 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338758&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53323500 125088860 CHEMBL1684384 ZINC66102938 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627634 CCOC(=O)c1ccc(OCc2ccccc2)c(NS(=O)(=O)Cc2cccc(c2)C2(CCOCC2)OC)c1 InChI=1S/C29H33NO7S/c1-3-36-28(31)24-12-13-27(37-20-22-8-5-4-6-9-22)26(19-24)30-38(32,33)21-23-10-7-11-25(18-23)29(34-2)14-16-35-17-15-29/h4-13,18-19,30H,3,14-17,20-21H2,1-2H3 SCHTUKZESKGPOR-UHFFFAOYSA-N 50338759 CHEMBL1684385::Ethyl 4-(benzyloxy)-3-((3-(4-methoxytetrahydro-2Hpyran-4-yl)phenyl)methylsulfonamido)benzoate Prostaglandin G/H synthase 2 Ovis aries 970 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338759&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53322159 125088861 CHEMBL1684385 ZINC66073915 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627635 COC1(CCOCC1)c1cccc(CN(c2ccccc2OCc2ccccc2)S(C)(=O)=O)c1 InChI=1S/C27H31NO5S/c1-31-27(15-17-32-18-16-27)24-12-8-11-23(19-24)20-28(34(2,29)30)25-13-6-7-14-26(25)33-21-22-9-4-3-5-10-22/h3-14,19H,15-18,20-21H2,1-2H3 QQVPHDTXMGWCCI-UHFFFAOYSA-N 50338760 CHEMBL1684386::N-(2-(Benzyloxy)phenyl)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)methanesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338760&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53324810 125088862 CHEMBL1684386 ZINC66074255 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627636 COC1(CCOCC1)c1cccc(CN(c2ccc(Cl)cc2OCc2ccccc2)S(C)(=O)=O)c1 InChI=1S/C27H30ClNO5S/c1-32-27(13-15-33-16-14-27)23-10-6-9-22(17-23)19-29(35(2,30)31)25-12-11-24(28)18-26(25)34-20-21-7-4-3-5-8-21/h3-12,17-18H,13-16,19-20H2,1-2H3 JOUJSWZHVMSGGA-UHFFFAOYSA-N 50338761 CHEMBL1684387::N-(2-(Benzyloxy)-4-chlorophenyl)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)methanesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338761&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53322985 125088863 CHEMBL1684387 ZINC66074256 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627637 COC1(CCOCC1)c1cccc(CN(c2cc(Cl)ccc2OCc2ccccc2)S(C)(=O)=O)c1 InChI=1S/C27H30ClNO5S/c1-32-27(13-15-33-16-14-27)23-10-6-9-22(17-23)19-29(35(2,30)31)25-18-24(28)11-12-26(25)34-20-21-7-4-3-5-8-21/h3-12,17-18H,13-16,19-20H2,1-2H3 QJAIKMCJSPKJBX-UHFFFAOYSA-N 50338762 CHEMBL1684388::N-(2-(Benzyloxy)-5-chlorophenyl)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)methanesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338762&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53323501 125088864 CHEMBL1684388 ZINC66105001 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627638 COC1(CCOCC1)c1cccc(CN(c2cc(C)ccc2OCc2ccccc2)S(C)(=O)=O)c1 InChI=1S/C28H33NO5S/c1-22-12-13-27(34-21-23-8-5-4-6-9-23)26(18-22)29(35(3,30)31)20-24-10-7-11-25(19-24)28(32-2)14-16-33-17-15-28/h4-13,18-19H,14-17,20-21H2,1-3H3 PAWZSNPAHOLHJM-UHFFFAOYSA-N 50338763 CHEMBL1684389::N-(2-(Benzyloxy)-5-methylphenyl)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)methanesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338763&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53320827 125088865 CHEMBL1684389 ZINC66105003 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627639 COC1(CCOCC1)c1cccc(CN(c2ccc(cc2OCc2ccccc2)[N+]([O-])=O)S(C)(=O)=O)c1 InChI=1S/C27H30N2O7S/c1-34-27(13-15-35-16-14-27)23-10-6-9-22(17-23)19-28(37(2,32)33)25-12-11-24(29(30)31)18-26(25)36-20-21-7-4-3-5-8-21/h3-12,17-18H,13-16,19-20H2,1-2H3 GGPMFHZDIZOOTM-UHFFFAOYSA-N 50338764 CHEMBL1684390::N-(2-(benzyloxy)-4-nitrophenyl)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)methanesulfonamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338764&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53324233 125088866 CHEMBL1684390 ZINC66105005 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627640 COC1(CCOCC1)c1cccc(CNc2ccccc2OCc2ccccc2)c1 InChI=1S/C26H29NO3/c1-28-26(14-16-29-17-15-26)23-11-7-10-22(18-23)19-27-24-12-5-6-13-25(24)30-20-21-8-3-2-4-9-21/h2-13,18,27H,14-17,19-20H2,1H3 BLNOQDIJOUQSBO-UHFFFAOYSA-N 50338765 2-(Benzyloxy)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)aniline::CHEMBL1684391 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338765&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53316868 125088867 CHEMBL1684391 ZINC66074655 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627641 COC1(CCOCC1)c1cccc(CNc2ccc(Cl)cc2OCc2ccccc2)c1 InChI=1S/C26H28ClNO3/c1-29-26(12-14-30-15-13-26)22-9-5-8-21(16-22)18-28-24-11-10-23(27)17-25(24)31-19-20-6-3-2-4-7-20/h2-11,16-17,28H,12-15,18-19H2,1H3 MVOJRCPNRMAZTO-UHFFFAOYSA-N 50338766 2-(Benzyloxy)-4-chloro-N-(3-(4-methoxytetrahydro-2Hpyran-4-yl)benzyl)aniline::CHEMBL1684392 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338766&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53322160 125088868 CHEMBL1684392 ZINC66074657 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627642 COC1(CCOCC1)c1cccc(CNc2cc(Cl)ccc2OCc2ccccc2)c1 InChI=1S/C26H28ClNO3/c1-29-26(12-14-30-15-13-26)22-9-5-8-21(16-22)18-28-24-17-23(27)10-11-25(24)31-19-20-6-3-2-4-7-20/h2-11,16-17,28H,12-15,18-19H2,1H3 ULQIXNNBCPCBFB-UHFFFAOYSA-N 50338767 2-(Benzyloxy)-5-chloro-N-(3-(4-methoxytetrahydro-2Hpyran-4-yl)benzyl)aniline::CHEMBL1684393 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338767&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53316869 125088869 CHEMBL1684393 ZINC66074659 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627643 COC1(CCOCC1)c1cccc(CNc2cc(C)ccc2OCc2ccccc2)c1 InChI=1S/C27H31NO3/c1-21-11-12-26(31-20-22-7-4-3-5-8-22)25(17-21)28-19-23-9-6-10-24(18-23)27(29-2)13-15-30-16-14-27/h3-12,17-18,28H,13-16,19-20H2,1-2H3 NGGVYDTUHQDIHZ-UHFFFAOYSA-N 50338768 2-(Benzyloxy)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)-5-methylaniline::CHEMBL1684394 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338768&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53318188 125088870 CHEMBL1684394 ZINC66077856 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627644 COC1(CCOCC1)c1cccc(CNc2ccc(cc2OCc2ccccc2)[N+]([O-])=O)c1 InChI=1S/C26H28N2O5/c1-31-26(12-14-32-15-13-26)22-9-5-8-21(16-22)18-27-24-11-10-23(28(29)30)17-25(24)33-19-20-6-3-2-4-7-20/h2-11,16-17,27H,12-15,18-19H2,1H3 FHXVUPSSYZRGCU-UHFFFAOYSA-N 50338769 2-(benzyloxy)-N-(3-(4-methoxytetrahydro-2H-pyran-4-yl)benzyl)-4-nitroaniline::CHEMBL1684395 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338769&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53319539 125088871 CHEMBL1684395 ZINC66077857 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627645 COC1(CCOCC1)c1cccc(COc2ccccc2OCc2ccccc2)c1 InChI=1S/C26H28O4/c1-27-26(14-16-28-17-15-26)23-11-7-10-22(18-23)20-30-25-13-6-5-12-24(25)29-19-21-8-3-2-4-9-21/h2-13,18H,14-17,19-20H2,1H3 LMFJAGUTULBTEC-UHFFFAOYSA-N 50338770 4-(3-((2-(Benzyloxy)phenoxy)methyl)phenyl)-4-methoxytetrahydro-2H-pyran::CHEMBL1684396 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338770&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53326087 125088872 CHEMBL1684396 ZINC66078495 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627646 COC1(CCOCC1)c1cccc(COc2ccc(Cl)cc2OCc2ccccc2)c1 InChI=1S/C26H27ClO4/c1-28-26(12-14-29-15-13-26)22-9-5-8-21(16-22)19-30-24-11-10-23(27)17-25(24)31-18-20-6-3-2-4-7-20/h2-11,16-17H,12-15,18-19H2,1H3 KMKLLICJOBGWGD-UHFFFAOYSA-N 50338771 4-(3-((2-(Benzyloxy)-4-chlorophenoxy)methyl)phenyl)-4-methoxytetrahydro-2H-pyran::CHEMBL1684397 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338771&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53326088 125088873 CHEMBL1684397 ZINC66066374 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627647 COC1(CCOCC1)c1cccc(COc2ccc(Br)cc2OCc2ccccc2)c1 InChI=1S/C26H27BrO4/c1-28-26(12-14-29-15-13-26)22-9-5-8-21(16-22)19-30-24-11-10-23(27)17-25(24)31-18-20-6-3-2-4-7-20/h2-11,16-17H,12-15,18-19H2,1H3 ZNOFUECSUAGUDH-UHFFFAOYSA-N 50338772 4-(3-((2-(Benzyloxy)-4-bromophenoxy)methyl)phenyl)-4-methoxytetrahydro-2H-pyran::CHEMBL1684398 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338772&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53322897 125088874 CHEMBL1684398 ZINC66073623 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627648 CCOC(=O)c1ccc(OCc2cccc(c2)C2(CCOCC2)OC)c(OCc2ccccc2)c1 InChI=1S/C29H32O6/c1-3-33-28(30)24-12-13-26(27(19-24)35-20-22-8-5-4-6-9-22)34-21-23-10-7-11-25(18-23)29(31-2)14-16-32-17-15-29/h4-13,18-19H,3,14-17,20-21H2,1-2H3 JFDYMAYITSPEBQ-UHFFFAOYSA-N 50338773 CHEMBL1684399::Ethyl 3-(benzyloxy)-4-(3-(4-methoxytetrahydro-2Hpyran4-yl)benzyloxy)benzoate Prostaglandin G/H synthase 2 Ovis aries 38800 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50338773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50338773&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53318189 125088875 CHEMBL1684399 ZINC66073624 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627649 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50627650 CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1)[N+]([O-])=O InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3 HYWYRSMBCFDLJT-UHFFFAOYSA-N 50056999 CHEMBL56367::nimesulide Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.1016/j.bmc.2011.01.043 10.7270/Q2GF0TSP 21349729 Li, Y; Chen, SH; Ou, TM; Tan, JH; Li, D; Gu, LQ; Huang, ZS Sun Yat-sen University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056999&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NIM 1ZWP,3N8X,3E9X,2OTH,4EIX 4495 103953101 44445 CHEMBL56367 DB04743 ZINC04617749 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616921 Fc1ccc(NC(=O)c2ccc[nH]c2=O)cc1 InChI=1S/C12H9FN2O2/c13-8-3-5-9(6-4-8)15-12(17)10-2-1-7-14-11(10)16/h1-7H,(H,14,16)(H,15,17) JCKDFUZFSKZSQI-UHFFFAOYSA-N 50334320 CHEMBL1643002::N-(4-fluorophenyl)-2-hydroxynicotinamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334320&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 42053506 125084422 CHEMBL1643002 ZINC11595490 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616922 Clc1ccc(NC(=O)c2ccc[nH]c2=O)cc1 InChI=1S/C12H9ClN2O2/c13-8-3-5-9(6-4-8)15-12(17)10-2-1-7-14-11(10)16/h1-7H,(H,14,16)(H,15,17) WGBFNTLEPRSHQA-UHFFFAOYSA-N 50334321 CHEMBL1643003::N-(4-chlorophenyl)-2-hydroxynicotinamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334321&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53323386 125084423 CHEMBL1643003 ZINC60617296 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616923 Fc1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1 InChI=1S/C12H9FN2O2/c13-9-2-4-10(5-3-9)15-12(17)8-1-6-11(16)14-7-8/h1-7H,(H,14,16)(H,15,17) HQLPHPCOVPGBEA-UHFFFAOYSA-N 50334322 CHEMBL1643016::N-(4-fluorophenyl)-6-hydroxynicotinamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334322&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 8745096 125084424 CHEMBL1643016 ZINC07639070 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616924 Clc1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1 InChI=1S/C12H9ClN2O2/c13-9-2-4-10(5-3-9)15-12(17)8-1-6-11(16)14-7-8/h1-7H,(H,14,16)(H,15,17) RCNOFDYZWOTAOC-UHFFFAOYSA-N 50334323 CHEMBL1643017::N-(4-chlorophenyl)-6-hydroxynicotinamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334323&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 8762448 125084425 CHEMBL1643017 ZINC14429371 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616925 Brc1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1 InChI=1S/C12H9BrN2O2/c13-9-2-4-10(5-3-9)15-12(17)8-1-6-11(16)14-7-8/h1-7H,(H,14,16)(H,15,17) LYMMDLUNGQCQDB-UHFFFAOYSA-N 50334324 CHEMBL1643018::N-(4-bromophenyl)-6-hydroxynicotinamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334324&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 17419961 125084426 CHEMBL1643018 ZINC15613642 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616926 COc1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1 InChI=1S/C13H12N2O3/c1-18-11-5-3-10(4-6-11)15-13(17)9-2-7-12(16)14-8-9/h2-8H,1H3,(H,14,16)(H,15,17) LYMQJIFMOXVDLL-UHFFFAOYSA-N 50334325 6-Hydroxy-N-(4-methoxyphenyl)nicotinamide::CHEMBL1643020 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334325&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 7988040 125084427 CHEMBL1643020 ZINC16598121 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616927 Cc1ccc(cn1)C(=O)Nc1ccc(F)cc1 InChI=1S/C13H11FN2O/c1-9-2-3-10(8-15-9)13(17)16-12-6-4-11(14)5-7-12/h2-8H,1H3,(H,16,17) UJCATKQYYWSMJP-UHFFFAOYSA-N 50334326 CHEMBL1643021::N-(4-fluorophenyl)-6-methylnicotinamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334326&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 18148012 125084428 CHEMBL1643021 ZINC32895350 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616928 Fc1ccc(NC(=O)c2c[nH]c(=O)c(Cl)c2)cc1 InChI=1S/C12H8ClFN2O2/c13-10-5-7(6-15-12(10)18)11(17)16-9-3-1-8(14)2-4-9/h1-6H,(H,15,18)(H,16,17) UDEPTCPFQXBOGX-UHFFFAOYSA-N 50334327 5-Chloro-N-(4-fluorophenyl)-6-hydroxynicotinamide::CHEMBL1642990 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334327&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 47293680 125084429 CHEMBL1642990 ZINC48666796 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616929 Clc1ccc(NC(=O)c2c[nH]c(=O)c(Cl)c2)cc1 InChI=1S/C12H8Cl2N2O2/c13-8-1-3-9(4-2-8)16-11(17)7-5-10(14)12(18)15-6-7/h1-6H,(H,15,18)(H,16,17) MKMPGKHNIPIEAL-UHFFFAOYSA-N 50334328 5-Chloro-N-(4-chlorophenyl)-6-hydroxynicotinamide::CHEMBL1642991 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334328&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 47299609 125084430 CHEMBL1642991 ZINC48666896 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616930 Clc1cc(c[nH]c1=O)C(=O)Nc1ccc(Br)cc1 InChI=1S/C12H8BrClN2O2/c13-8-1-3-9(4-2-8)16-11(17)7-5-10(14)12(18)15-6-7/h1-6H,(H,15,18)(H,16,17) BPWPNIKIZZGMGO-UHFFFAOYSA-N 50334329 CHEMBL1642992::N-(4-bromophenyl)-5-chloro-6-hydroxynicotinamide Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334329&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53318085 125084431 CHEMBL1642992 ZINC54348013 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616931 Cc1ccc(NC(=O)c2c[nH]c(=O)c(Cl)c2)cc1 InChI=1S/C13H11ClN2O2/c1-8-2-4-10(5-3-8)16-12(17)9-6-11(14)13(18)15-7-9/h2-7H,1H3,(H,15,18)(H,16,17) YIDXVQYPMCXTOW-UHFFFAOYSA-N 50334330 5-Chloro-6-hydroxy-N-p-tolylnicotinamide::CHEMBL1642993 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334330&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 47292592 125084432 CHEMBL1642993 ZINC48666864 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616932 COc1ccc(NC(=O)c2c[nH]c(=O)c(Cl)c2)cc1 InChI=1S/C13H11ClN2O3/c1-19-10-4-2-9(3-5-10)16-12(17)8-6-11(14)13(18)15-7-8/h2-7H,1H3,(H,15,18)(H,16,17) WRGAORQJBHERPH-UHFFFAOYSA-N 50334331 5-Chloro-6-hydroxy-N-(4-methoxyphenyl)nicotinamide::CHEMBL1642994 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334331&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 47292593 125084433 CHEMBL1642994 ZINC48666869 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616933 Clc1ccc(NC(=O)c2c[nH]c(=O)c(Cl)c2)c(Cl)c1 InChI=1S/C12H7Cl3N2O2/c13-7-1-2-10(8(14)4-7)17-11(18)6-3-9(15)12(19)16-5-6/h1-5H,(H,16,19)(H,17,18) PGAAWBFRYWDGPK-UHFFFAOYSA-N 50334332 5-Chloro-N-(2,4-dichlorophenyl)-6-hydroxynicotinamide::CHEMBL1642995 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334332&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53324704 125084434 CHEMBL1642995 ZINC66104727 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616934 Clc1cc(Cl)cc(NC(=O)c2c[nH]c(=O)c(Cl)c2)c1 InChI=1S/C12H7Cl3N2O2/c13-7-2-8(14)4-9(3-7)17-11(18)6-1-10(15)12(19)16-5-6/h1-5H,(H,16,19)(H,17,18) YKUWFTPGUOAXPB-UHFFFAOYSA-N 50334333 5-Chloro-N-(3,5-dichlorophenyl)-6-hydroxynicotinamide::CHEMBL1642996 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334333&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53318086 125084435 CHEMBL1642996 ZINC66157211 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50616935 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.bmcl.2010.11.062 10.7270/Q2571C83 21144750 Shi, L; Li, ZL; Yang, Y; Zhu, ZW; Zhu, HL Nanjing University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50613315 CCCCCCCCCCCC(=O)O[C@H]1[C@H](C)O[C@@H](O[C@H]2[C@H](C)O[C@@H](O[C@H]3[C@H](C)O[C@H]4O[C@@H]5[C@@H](O)[C@@H](O)[C@@H](C)O[C@H]5O[C@@H](CCCCC)CCCCCCCCCC(=O)O[C@@H]4[C@@H]3O)[C@H](O)[C@@H]2OC(=O)CCCCCCCCC)[C@H](OC(=O)\C=C\c2ccccc2)[C@@H]1O InChI=1S/C71H116O21/c1-8-11-14-16-18-19-23-27-34-41-52(72)86-61-47(5)83-70(66(58(61)78)89-55(75)45-44-50-37-31-29-32-38-50)91-63-49(7)82-68(60(80)64(63)87-53(73)42-35-26-21-17-15-12-9-2)90-62-48(6)84-71-67(59(62)79)88-54(74)43-36-28-24-20-22-25-33-40-51(39-30-13-10-3)85-69-65(92-71)57(77)56(76)46(4)81-69/h29,31-32,37-38,44-49,51,56-71,76-80H,8-28,30,33-36,39-43H2,1-7H3/b45-44+/t46-,47+,48+,49+,51+,56+,57+,58-,59-,60-,61+,62+,63+,64+,65-,66-,67-,68+,69+,70+,71+/m1/s1 RWELBFDBNJXLOK-RQSNGXSLSA-N 50332939 (S)-jalapinolic acid 11-O-(2-O-trans-cinnamoyl)-[(4-O-n-dodecanoyl)]-alpha-L-rhamnopyranosyl-(1->4)-O-(3-O-n-decanoyl)-alpha-L-rhamnopyranosyl-(1->4)-O-alpha-L-rhamnopyranosyl-(1->2)-O-beta-D-fucopyranoside 1,2'' ester::CHEMBL1631409 Prostaglandin G/H synthase 2 Ovis aries 14500 ChEMBL 10.1021/np100283t 10.7270/Q2JW8F4R 20961090 Yoshikawa, K; Yagi, C; Hama, H; Tanaka, M; Arihara, S; Hashimoto, T Tokushima Bunri University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332939&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 50900934 125083041 70318 CHEMBL1631409 C06357 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50613317 CCCCCCCCCCCC(=O)O[C@H]1[C@H](C)O[C@@H](O[C@H]2[C@H](C)O[C@@H](O[C@H]3[C@H](C)O[C@H]4O[C@@H]5[C@@H](O)[C@@H](O)[C@@H](C)O[C@H]5O[C@@H](CCCCC)CCCCCCCCCC(=O)O[C@@H]4[C@@H]3O)[C@H](OC(=O)CCCCCCCCCCC)[C@@H]2O)[C@H](OC(=O)\C=C\c2ccccc2)[C@@H]1O InChI=1S/C73H120O21/c1-8-11-14-16-18-20-24-28-36-43-54(74)88-63-49(5)84-71(67(60(63)80)91-57(77)47-46-52-39-33-31-34-40-52)92-64-50(6)85-72(68(61(64)81)89-55(75)44-37-29-25-21-19-17-15-12-9-2)93-65-51(7)86-73-69(62(65)82)90-56(76)45-38-30-26-22-23-27-35-42-53(41-32-13-10-3)87-70-66(94-73)59(79)58(78)48(4)83-70/h31,33-34,39-40,46-51,53,58-73,78-82H,8-30,32,35-38,41-45H2,1-7H3/b47-46+/t48-,49+,50+,51+,53+,58+,59+,60-,61-,62-,63+,64+,65+,66-,67-,68-,69-,70+,71+,72+,73+/m1/s1 FSDJTONUQZBFFY-QSAXEEFWSA-N 50332940 (S)-jalapinolic acid 11-O-(2-O-trans-cinnamoyl)-[(4-O-n-dodecanoyl)]-alpha-L-rhamnopyranosyl-(1->4)-O-(2-O-n-dodecanoyl)-alpha-L-rhamnopyranosyl-(1->4)-O-alpha-L-rhamnopyranosyl-(1->2)-O-beta-D-fucopyranoside 1,2'' ester::CHEMBL1631410 Prostaglandin G/H synthase 2 Ovis aries 147000 ChEMBL 10.1021/np100283t 10.7270/Q2JW8F4R 20961090 Yoshikawa, K; Yagi, C; Hama, H; Tanaka, M; Arihara, S; Hashimoto, T Tokushima Bunri University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332940&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 50901029 125083042 70319 CHEMBL1631410 C06357 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50613319 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 13900 ChEMBL 10.1021/np100283t 10.7270/Q2JW8F4R 20961090 Yoshikawa, K; Yagi, C; Hama, H; Tanaka, M; Arihara, S; Hashimoto, T Tokushima Bunri University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50644695 CS(=O)(=O)c1ccc(cc1)C1SCCC(=O)N1Cc1ccccc1 InChI=1S/C18H19NO3S2/c1-24(21,22)16-9-7-15(8-10-16)18-19(17(20)11-12-23-18)13-14-5-3-2-4-6-14/h2-10,18H,11-13H2,1H3 USOQSXIGNMPKGV-UHFFFAOYSA-N 50346138 3-benzyl-2-(4-(methylsulfonyl)phenyl)-1,3-thiazinan-4-one::CHEMBL1782322 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmcl.2009.04.125 10.7270/Q2XG9RGM 19447036 Zebardast, T; Zarghi, A; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346138&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44224202 131349069 CHEMBL1782322 ZINC71296095 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50644696 CS(=O)(=O)c1ccc(cc1)C1SCCC(=O)N1CCc1ccccc1 InChI=1S/C19H21NO3S2/c1-25(22,23)17-9-7-16(8-10-17)19-20(18(21)12-14-24-19)13-11-15-5-3-2-4-6-15/h2-10,19H,11-14H2,1H3 WNYAMJLZANBXDA-UHFFFAOYSA-N 50346139 2-(4-(methylsulfonyl)phenyl)-3-phenethyl-1,3-thiazinan-4-one::CHEMBL1782323 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmcl.2009.04.125 10.7270/Q2XG9RGM 19447036 Zebardast, T; Zarghi, A; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346139&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54584102 131349070 CHEMBL1782323 ZINC71281315 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50644697 CCCN1C(SCCC1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C14H19NO3S2/c1-3-9-15-13(16)8-10-19-14(15)11-4-6-12(7-5-11)20(2,17)18/h4-7,14H,3,8-10H2,1-2H3 ZAJCFIDMYFWECY-UHFFFAOYSA-N 50346140 2-(4-(methylsulfonyl)phenyl)-3-propyl-1,3-thiazinan-4-one::CHEMBL1782325 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.bmcl.2009.04.125 10.7270/Q2XG9RGM 19447036 Zebardast, T; Zarghi, A; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346140&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54582153 131349071 CHEMBL1782325 ZINC71295734 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50644698 CCCCN1C(SCCC1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C15H21NO3S2/c1-3-4-10-16-14(17)9-11-20-15(16)12-5-7-13(8-6-12)21(2,18)19/h5-8,15H,3-4,9-11H2,1-2H3 ATHPXLRNNFYYKT-UHFFFAOYSA-N 50346141 3-butyl-2-(4-(methylsulfonyl)phenyl)-1,3-thiazinan-4-one::CHEMBL1782326 Prostaglandin G/H synthase 2 Ovis aries 80 ChEMBL 10.1016/j.bmcl.2009.04.125 10.7270/Q2XG9RGM 19447036 Zebardast, T; Zarghi, A; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346141&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54583106 131349072 CHEMBL1782326 ZINC71295883 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50644699 CCCCCN1C(SCCC1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C16H23NO3S2/c1-3-4-5-11-17-15(18)10-12-21-16(17)13-6-8-14(9-7-13)22(2,19)20/h6-9,16H,3-5,10-12H2,1-2H3 VHPQDQVJBTUVDC-UHFFFAOYSA-N 50346142 2-(4-(methylsulfonyl)phenyl)-3-pentyl-1,3-thiazinan-4-one::CHEMBL1782327 Prostaglandin G/H synthase 2 Ovis aries 80 ChEMBL 10.1016/j.bmcl.2009.04.125 10.7270/Q2XG9RGM 19447036 Zebardast, T; Zarghi, A; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346142&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54586995 131349073 CHEMBL1782327 ZINC71296184 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50644700 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmcl.2009.04.125 10.7270/Q2XG9RGM 19447036 Zebardast, T; Zarghi, A; Daraie, B; Hedayati, M; Dadrass, OG Shahid Beheshti University (M.C) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637099 COc1cc(cc(OC)c1OC)-n1c(O)ccc1O InChI=1S/C13H15NO5/c1-17-9-6-8(7-10(18-2)13(9)19-3)14-11(15)4-5-12(14)16/h4-7,15-16H,1-3H3 IPSZGSLMVFLLPP-UHFFFAOYSA-N 50342791 1-(3,4,5-Trimethoxyphenyl)pyrrolidine-2,5-dione::CHEMBL1770577 Prostaglandin G/H synthase 2 Ovis aries 40000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342791&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91932444 131345727 CHEMBL1770577 ZINC71418552 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637100 Oc1ccc(O)n1-c1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C10H6Cl3NO2/c11-6-3-5(4-7(12)10(6)13)14-8(15)1-2-9(14)16/h1-4,15-16H QTZFBPDLVCLKIL-UHFFFAOYSA-N 50342792 1-(3,4,5-trichlorophenyl)pyrrolidine-2,5-dione::CHEMBL1770578 Prostaglandin G/H synthase 2 Ovis aries 40000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342792&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54247034 131345728 CHEMBL1770578 ZINC06091202 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637101 COc1cc(cc(OC)c1OC)-n1c(O)c2CC=CCc2c1O InChI=1S/C17H19NO5/c1-21-13-8-10(9-14(22-2)15(13)23-3)18-16(19)11-6-4-5-7-12(11)17(18)20/h4-5,8-9,19-20H,6-7H2,1-3H3 HKDMCINAXZWWPG-UHFFFAOYSA-N 50342793 CHEMBL1770579::cis-2-(3,4,5-Trimethoxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342793&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91932445 131345729 CHEMBL1770579 ZINC71340712 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637102 Oc1c2CC=CCc2c(O)n1-c1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C14H10Cl3NO2/c15-10-5-7(6-11(16)12(10)17)18-13(19)8-3-1-2-4-9(8)14(18)20/h1-2,5-6,19-20H,3-4H2 KCOGFQYCYKLUDK-UHFFFAOYSA-N 50342794 CHEMBL1770580::cis-2-(3,4,5-Trichlorophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342794&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91932446 131345730 CHEMBL1770580 ZINC71341714 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637103 COc1cc(cc(OC)c1OC)N1C(=O)c2nccnc2C1=O InChI=1S/C15H13N3O5/c1-21-9-6-8(7-10(22-2)13(9)23-3)18-14(19)11-12(15(18)20)17-5-4-16-11/h4-7H,1-3H3 JNESZYJVSXNOJC-UHFFFAOYSA-N 50342795 6-(3,4,5-trimethoxyphenyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione::CHEMBL1770581 Prostaglandin G/H synthase 2 Ovis aries 5200 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342795&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231774 131345731 CHEMBL1770581 ZINC71332291 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637104 Clc1cc(cc(Cl)c1Cl)N1C(=O)c2nccnc2C1=O InChI=1S/C12H4Cl3N3O2/c13-6-3-5(4-7(14)8(6)15)18-11(19)9-10(12(18)20)17-2-1-16-9/h1-4H YMNSMFPTKNHFBB-UHFFFAOYSA-N 50342796 6-(3,4,5-Trichlorophenyl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione::CHEMBL1770582 Prostaglandin G/H synthase 2 Ovis aries 10500 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342796&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231775 131345732 CHEMBL1770582 ZINC71335347 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637105 COc1cc(cc(OC)c1OC)N1C(=O)c2ccccc2C1=O InChI=1S/C17H15NO5/c1-21-13-8-10(9-14(22-2)15(13)23-3)18-16(19)11-6-4-5-7-12(11)17(18)20/h4-9H,1-3H3 XEQSSIABKLVMDD-UHFFFAOYSA-N 50342797 2-(3,4,5-Trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770583 Prostaglandin G/H synthase 2 Ovis aries 6400 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342797&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231776 131345733 CHEMBL1770583 ZINC71340471 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637106 Clc1cc(cc(Cl)c1Cl)N1C(=O)c2ccccc2C1=O InChI=1S/C14H6Cl3NO2/c15-10-5-7(6-11(16)12(10)17)18-13(19)8-3-1-2-4-9(8)14(18)20/h1-6H STAUHFKKYJZTIX-UHFFFAOYSA-N 50342798 2-(3,4,5-Trichlorophenyl)isoindoline-1,3-dione::CHEMBL1770584 Prostaglandin G/H synthase 2 Ovis aries 9100 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342798&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231777 131345734 CHEMBL1770584 ZINC71341299 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637107 COc1cc(cc(OC)c1OC)N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O InChI=1S/C17H14N2O7/c1-24-13-7-10(8-14(25-2)15(13)26-3)18-16(20)11-5-4-9(19(22)23)6-12(11)17(18)21/h4-8H,1-3H3 FCQFHRMDZZRIPV-UHFFFAOYSA-N 50342799 5-Nitro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770585 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342799&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 52952951 131345735 CHEMBL1770585 ZINC71334509 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637108 [O-][N+](=O)c1ccc2C(=O)N(C(=O)c2c1)c1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C14H5Cl3N2O4/c15-10-4-7(5-11(16)12(10)17)18-13(20)8-2-1-6(19(22)23)3-9(8)14(18)21/h1-5H CKUHUIXBEJDSQR-UHFFFAOYSA-N 50342800 5-Nitro-2-(3,4,5-trichlorophenyl)isoindoline-1,3-dione::CHEMBL1770586 Prostaglandin G/H synthase 2 Ovis aries 40000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342800&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231778 131345736 CHEMBL1770586 ZINC71405032 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637109 COc1cc(cc(OC)c1OC)N1C(=O)c2ccc(C)cc2C1=O InChI=1S/C18H17NO5/c1-10-5-6-12-13(7-10)18(21)19(17(12)20)11-8-14(22-2)16(24-4)15(9-11)23-3/h5-9H,1-4H3 LYZAOROCZZOGTL-UHFFFAOYSA-N 50342801 5-Methyl-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770587 Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342801&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 3528757 131345737 CHEMBL1770587 ZINC02795867 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637110 Cc1ccc2C(=O)N(C(=O)c2c1)c1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C15H8Cl3NO2/c1-7-2-3-9-10(4-7)15(21)19(14(9)20)8-5-11(16)13(18)12(17)6-8/h2-6H,1H3 UAQIZUOPEZZQCR-UHFFFAOYSA-N 50342802 5-Methyl-2-(3,4,5-trichlorophenyl)isoindoline-1,3-dione::CHEMBL1770588 Prostaglandin G/H synthase 2 Ovis aries 19500 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342802&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231887 131345738 CHEMBL1770588 ZINC71341748 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637111 COc1cc(cc(OC)c1OC)N1C(=O)c2ccc(cc2C1=O)C(C)(C)C InChI=1S/C21H23NO5/c1-21(2,3)12-7-8-14-15(9-12)20(24)22(19(14)23)13-10-16(25-4)18(27-6)17(11-13)26-5/h7-11H,1-6H3 UCKCQKFFYZEKJR-UHFFFAOYSA-N 50342803 5-Tert-Butyl-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770589 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342803&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231889 131345739 CHEMBL1770589 ZINC71342100 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637112 CC(C)(C)c1ccc2C(=O)N(C(=O)c2c1)c1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C18H14Cl3NO2/c1-18(2,3)9-4-5-11-12(6-9)17(24)22(16(11)23)10-7-13(19)15(21)14(20)8-10/h4-8H,1-3H3 ZRXYOWQFZOBFSN-UHFFFAOYSA-N 50342804 5-tert-Butyl-2-(3,4,5-trichlorophenyl)isoindoline-1,3-dione::CHEMBL1770590 Prostaglandin G/H synthase 2 Ovis aries 20700 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342804&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231890 131345740 CHEMBL1770590 ZINC71331646 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637113 COc1cc(cc(OC)c1OC)N1C(=O)c2cc(Cl)c(Cl)cc2C1=O InChI=1S/C17H13Cl2NO5/c1-23-13-4-8(5-14(24-2)15(13)25-3)20-16(21)9-6-11(18)12(19)7-10(9)17(20)22/h4-7H,1-3H3 DRRPERJPOWCAOA-UHFFFAOYSA-N 50342805 5,6-Dichloro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770591 Prostaglandin G/H synthase 2 Ovis aries 12400 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342805&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231891 131345741 CHEMBL1770591 ZINC71341005 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637114 Clc1cc2C(=O)N(C(=O)c2cc1Cl)c1cc(Cl)c(Cl)c(Cl)c1 InChI=1S/C14H4Cl5NO2/c15-8-3-6-7(4-9(8)16)14(22)20(13(6)21)5-1-10(17)12(19)11(18)2-5/h1-4H WIBREDYTHGOZCE-UHFFFAOYSA-N 50342806 5,6-Dichloro-2-(3,4,5-trichlorophenyl)isoindoline-1,3-dione::CHEMBL1770592 Prostaglandin G/H synthase 2 Ovis aries 30100 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342806&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231892 131345742 CHEMBL1770592 ZINC71341700 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637115 COc1cc(cc(OC)c1OC)N1C(=O)c2c(C1=O)c(Cl)c(Cl)c(Cl)c2Cl InChI=1S/C17H11Cl4NO5/c1-25-7-4-6(5-8(26-2)15(7)27-3)22-16(23)9-10(17(22)24)12(19)14(21)13(20)11(9)18/h4-5H,1-3H3 RWNGNXIMUOVWHV-UHFFFAOYSA-N 50342807 4,5,6,7-Tetrachloro-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770593 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342807&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53231893 131345743 CHEMBL1770593 ZINC71341964 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637116 Clc1cc(cc(Cl)c1Cl)N1C(=O)c2c(C1=O)c(Cl)c(Cl)c(Cl)c2Cl InChI=1S/C14H2Cl7NO2/c15-4-1-3(2-5(16)8(4)17)22-13(23)6-7(14(22)24)10(19)12(21)11(20)9(6)18/h1-2H DQYUYLGCWJEMPF-UHFFFAOYSA-N 50342808 4,5,6,7-Tetrachloro-2-(3,4,5-trichlorophenyl)isoindoline-1,3-dione::CHEMBL1770594 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342808&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53232012 131345744 CHEMBL1770594 ZINC71341480 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637117 COc1cc(cc(OC)c1OC)N1C(=O)c2c(C1=O)c(Br)c(Br)c(Br)c2Br InChI=1S/C17H11Br4NO5/c1-25-7-4-6(5-8(26-2)15(7)27-3)22-16(23)9-10(17(22)24)12(19)14(21)13(20)11(9)18/h4-5H,1-3H3 FUJSFYORJDNWNJ-UHFFFAOYSA-N 50342809 4,5,6,7-Tetrabromo-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione::CHEMBL1770595 Prostaglandin G/H synthase 2 Ovis aries 65000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342809&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53232014 131345745 CHEMBL1770595 ZINC72106065 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637118 Clc1cc(cc(Cl)c1Cl)N1C(=O)c2c(C1=O)c(Br)c(Br)c(Br)c2Br InChI=1S/C14H2Br4Cl3NO2/c15-8-6-7(9(16)11(18)10(8)17)14(24)22(13(6)23)3-1-4(19)12(21)5(20)2-3/h1-2H XIAWFLUXPLYMDH-UHFFFAOYSA-N 50342810 4,5,6,7-Tetrabromo-2-(3,4,5-trichlorophenyl)isoindoline-1,3-dione::CHEMBL1770596 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342810&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54586700 131345746 CHEMBL1770596 ZINC72134091 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637119 COc1cc(cc(OC)c1OC)N1C(=O)c2cccc3cccc(C1=O)c23 InChI=1S/C21H17NO5/c1-25-16-10-13(11-17(26-2)19(16)27-3)22-20(23)14-8-4-6-12-7-5-9-15(18(12)14)21(22)24/h4-11H,1-3H3 IJCJOPTZJRPDFW-UHFFFAOYSA-N 50342811 2-(3,4,5-Trimethoxyphenyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione::CHEMBL1770597 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342811&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 52952987 131345747 CHEMBL1770597 ZINC71331210 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637120 Clc1cc(cc(Cl)c1Cl)N1C(=O)c2cccc3cccc(C1=O)c23 InChI=1S/C18H8Cl3NO2/c19-13-7-10(8-14(20)16(13)21)22-17(23)11-5-1-3-9-4-2-6-12(15(9)11)18(22)24/h1-8H KVJQOJJVSPXGPN-UHFFFAOYSA-N 50342812 2-(3,4,5-Trichlorophenyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione::CHEMBL1770156 Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342812&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 52952988 131345748 CHEMBL1770156 ZINC71418529 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637121 COc1cc(cc(OC)c1OC)-n1c(=O)c2ccccc2c2ccccc2c1=O InChI=1S/C23H19NO5/c1-27-19-12-14(13-20(28-2)21(19)29-3)24-22(25)17-10-6-4-8-15(17)16-9-5-7-11-18(16)23(24)26/h4-13H,1-3H3 NINRJZJPPYEPHU-UHFFFAOYSA-N 50342813 6-(3,4,5-Trimethoxyphenyl)-5H-dibenzo[c,e]azepine-5,7(6H)-dione::CHEMBL1770598 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342813&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 52952989 131345749 CHEMBL1770598 ZINC71331658 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637122 Clc1cc(cc(Cl)c1Cl)-n1c(=O)c2ccccc2c2ccccc2c1=O InChI=1S/C20H10Cl3NO2/c21-16-9-11(10-17(22)18(16)23)24-19(25)14-7-3-1-5-12(14)13-6-2-4-8-15(13)20(24)26/h1-10H VVBLTHNPQQVKDZ-UHFFFAOYSA-N 50342814 6-(3,4,5-Trichlorophenyl)-5H-dibenzo[c,e]azepine-5,7(6H)-dione::CHEMBL1770599 Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342814&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 52952990 131345750 CHEMBL1770599 ZINC71342041 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637123 COc1cc(cc(OC)c1OC)-n1c(O)c2c(c1O)C1(Cl)C(Cl)=C(Cl)C2(Cl)C1(Cl)Cl InChI=1S/C18H13Cl6NO5/c1-28-7-4-6(5-8(29-2)11(7)30-3)25-14(26)9-10(15(25)27)17(22)13(20)12(19)16(9,21)18(17,23)24/h4-5,26-27H,1-3H3 IPUBNLWPIQSOQV-UHFFFAOYSA-N 50342815 4,5,6,7,8,8-Hexachloro-2-(3,4,5-trimethoxyphenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione::CHEMBL1770600 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342815&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91932447 131345751 CHEMBL1770600 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637124 Oc1c2c(c(O)n1-c1cc(Cl)c(Cl)c(Cl)c1)C1(Cl)C(Cl)=C(Cl)C2(Cl)C1(Cl)Cl InChI=1S/C15H4Cl9NO2/c16-4-1-3(2-5(17)8(4)18)25-11(26)6-7(12(25)27)14(22)10(20)9(19)13(6,21)15(14,23)24/h1-2,26-27H VJYMILNUGRYJNQ-UHFFFAOYSA-N 50342816 4,5,6,7,8,8-Hexachloro-2-(3,4,5-trichlorophenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione::CHEMBL1770601 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342816&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91932448 131345752 CHEMBL1770601 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50637125 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.ejmech.2011.02.013 10.7270/Q29P31ZD 21388719 Abdel-Aziz, AA; ElTahir, KE; Asiri, YA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642106 FC(F)(F)c1nn(c(c1C=C1CCCCC1=O)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C23H18ClF3N2O/c24-17-12-10-15(11-13-17)21-19(14-16-6-4-5-9-20(16)30)22(23(25,26)27)28-29(21)18-7-2-1-3-8-18/h1-3,7-8,10-14H,4-6,9H2 OUCNFMVVGJIKBT-UHFFFAOYSA-N 50344873 2-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)cyclohexanone::CHEMBL1780078 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344873&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54584589 131347809 CHEMBL1780078 ZINC71331925 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642107 CN1CCC(=O)C(C1)=Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F InChI=1S/C23H19ClF3N3O/c1-29-12-11-20(31)16(14-29)13-19-21(15-7-9-17(24)10-8-15)30(18-5-3-2-4-6-18)28-22(19)23(25,26)27/h2-10,13H,11-12,14H2,1H3 JEFGGEGJSIGIPK-UHFFFAOYSA-N 50344874 3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-1-methylpiperidin-4-one::CHEMBL1780079 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344874&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54583599 131347810 CHEMBL1780079 ZINC71333259 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642108 CCN1CCC(=O)C(C1)=Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F InChI=1S/C24H21ClF3N3O/c1-2-30-13-12-21(32)17(15-30)14-20-22(16-8-10-18(25)11-9-16)31(19-6-4-3-5-7-19)29-23(20)24(26,27)28/h3-11,14H,2,12-13,15H2,1H3 JWMFCUROZUDFLT-UHFFFAOYSA-N 50344875 3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-1-ethylpiperidin-4-one::CHEMBL1780080 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344875&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53248924 131347811 CHEMBL1780080 ZINC71410724 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642109 FC(F)(F)c1nn(c(c1\C=C\C(=O)c1ccccc1)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C25H16ClF3N2O/c26-19-13-11-18(12-14-19)23-21(15-16-22(32)17-7-3-1-4-8-17)24(25(27,28)29)30-31(23)20-9-5-2-6-10-20/h1-16H/b16-15+ DXUUXOCHRBRBJJ-FOCLMDBBSA-N 50344876 3-(5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one::CHEMBL1780081 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344876&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54581654 131347812 CHEMBL1780081 ZINC71410945 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642110 FC(F)(F)c1nn(c(c1\C=C\C(=O)c1ccc(Cl)cc1)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C25H15Cl2F3N2O/c26-18-10-6-16(7-11-18)22(33)15-14-21-23(17-8-12-19(27)13-9-17)32(20-4-2-1-3-5-20)31-24(21)25(28,29)30/h1-15H/b15-14+ ZYNLHWCHBUPFHG-CCEZHUSRSA-N 50344877 1-(4-Chlorophenyl)-3-(5-(4-chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl))prop-2-en-1-one::CHEMBL1780082 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344877&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54580643 131347813 CHEMBL1780082 ZINC71340652 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642111 [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)/p-1 DCOPUUMXTXDBNB-UHFFFAOYSA-M 50174201 ARTHROTEC::GP 45840::SOLARAZE::Sodium; [2-(2,6-dichloro-phenylamino)-phenyl]-acetate::US11173137, Compound Diclofenac::VOLTAREN::VOLTAREN-XR::diclofenac sodium::sodium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate Prostaglandin G/H synthase 2 Ovis aries 2500 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174201&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 3032 104060023 4509 C01690 ZINC00001281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642112 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642113 FC(F)(F)c1nn(c(c1C=O)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C17H10ClF3N2O/c18-12-8-6-11(7-9-12)15-14(10-24)16(17(19,20)21)22-23(15)13-4-2-1-3-5-13/h1-10H YEBAWYVHPNUTJE-UHFFFAOYSA-N 50344878 5-(4-chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde::CHEMBL1780083 Prostaglandin G/H synthase 2 Ovis aries 550 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344878&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53248948 131347814 CHEMBL1780083 ZINC71340392 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642114 FC(F)(F)c1nn(c(c1C=C1CCCC1=O)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C22H16ClF3N2O/c23-16-11-9-14(10-12-16)20-18(13-15-5-4-8-19(15)29)21(22(24,25)26)27-28(20)17-6-2-1-3-7-17/h1-3,6-7,9-13H,4-5,8H2 RWQYQVMSGMZBAT-UHFFFAOYSA-N 50344879 2-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)cyclopentanone::CHEMBL1780077 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344879&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53248946 131347815 CHEMBL1780077 ZINC71341092 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642136 FC(F)(F)C(=O)C(=NNc1ccccc1Cl)C(=O)c1ccc(Cl)cc1 InChI=1S/C16H9Cl2F3N2O2/c17-10-7-5-9(6-8-10)14(24)13(15(25)16(19,20)21)23-22-12-4-2-1-3-11(12)18/h1-8,22H JXNBUXGRRAFKGY-UHFFFAOYSA-N 50344880 1-(4-Chlorophenyl)-2-(2-(2-chlorophenyl)hydrazone)-4,4,4-trifuorobutane-1,3-dione::CHEMBL1780065 Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344880&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54587536 131347816 CHEMBL1780065 ZINC71331097 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642137 FC(F)(F)C(=O)C(=NNc1ccc(Cl)cc1)C(=O)c1ccc(Cl)cc1 InChI=1S/C16H9Cl2F3N2O2/c17-10-3-1-9(2-4-10)14(24)13(15(25)16(19,20)21)23-22-12-7-5-11(18)6-8-12/h1-8,22H APVXNWRBIHZKNF-UHFFFAOYSA-N 50344881 1-(4-Chlorophenyl)-2-(2-(4-chlorophenyl)hydrazone)-4,4,4-trifuorobutane-1,3-dione::CHEMBL1780066 Prostaglandin G/H synthase 2 Ovis aries 910 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344881&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54587537 131347817 CHEMBL1780066 ZINC71334732 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642138 FC(F)(F)C(=O)C(=NNc1ccc(Br)cc1)C(=O)c1ccc(Cl)cc1 InChI=1S/C16H9BrClF3N2O2/c17-10-3-7-12(8-4-10)22-23-13(15(25)16(19,20)21)14(24)9-1-5-11(18)6-2-9/h1-8,22H IVMKFVZQGSPMEU-UHFFFAOYSA-N 50344882 1-(4-Chlorophenyl)-2-(2-(4-bromophenyl)hydrazone)-4,4,4-trifuorobutane-1,3-dione::CHEMBL1780067 Prostaglandin G/H synthase 2 Ovis aries 910 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344882&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54587538 131347818 CHEMBL1780067 ZINC71333149 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642139 [O-][N+](=O)c1ccc(NN=C(C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1 InChI=1S/C16H9ClF3N3O4/c17-10-3-1-9(2-4-10)14(24)13(15(25)16(18,19)20)22-21-11-5-7-12(8-6-11)23(26)27/h1-8,21H PSGKERPUNLRSLF-UHFFFAOYSA-N 50344883 1-(4-Chlorophenyl)-2-(2-(4-nitrophenyl)hydrazone)-4,4,4-trifuorobutane-1,3-dione::CHEMBL1780068 Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344883&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54586500 131347819 CHEMBL1780068 ZINC71335073 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642140 COc1ccc(NN=C(C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1 InChI=1S/C17H12ClF3N2O3/c1-26-13-8-6-12(7-9-13)22-23-14(16(25)17(19,20)21)15(24)10-2-4-11(18)5-3-10/h2-9,22H,1H3 NSOPECLWMQEDGD-UHFFFAOYSA-N 50344884 1-(4-Chlorophenyl)-2-(2-(4-methoxyphenyl)hydrazone)-4,4,4-trifuorobutane-1,3-dione::CHEMBL1780069 Prostaglandin G/H synthase 2 Ovis aries 2950 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344884&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 34306369 131347820 CHEMBL1780069 ZINC27015737 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642141 FC(F)(F)C(=O)C(=NNc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1ccc(Cl)cc1 InChI=1S/C18H8ClF9N2O2/c19-11-3-1-8(2-4-11)14(31)13(15(32)18(26,27)28)30-29-12-6-9(16(20,21)22)5-10(7-12)17(23,24)25/h1-7,29H KYHGSDBZLLKHSB-UHFFFAOYSA-N 50344885 1-(4-Chlorophenyl)-2-(2-(3,5-bis(trifluoromethyl)phenyl)hydrazone)-4,4,4-trifuorobutane-1,3-dione::CHEMBL1780070 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344885&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54584587 131347821 CHEMBL1780070 ZINC71334907 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642142 FC(F)(F)c1[nH]nc(c1N=Nc1ccccc1Cl)-c1ccc(Cl)cc1 InChI=1S/C16H9Cl2F3N4/c17-10-7-5-9(6-8-10)13-14(15(25-23-13)16(19,20)21)24-22-12-4-2-1-3-11(12)18/h1-8H,(H,23,25) AJFBMOKKTRIOQI-UHFFFAOYSA-N 50344886 3-(4-Chlorophenyl)-4-(2-(2-chlorophenyl)hydrazono)-5-trifuoromethyl)-4H-pyrazole::CHEMBL1780071 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344886&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54584588 131347822 CHEMBL1780071 ZINC71333402 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642143 FC(F)(F)c1[nH]nc(c1N=Nc1ccc(Cl)cc1)-c1ccc(Cl)cc1 InChI=1S/C16H9Cl2F3N4/c17-10-3-1-9(2-4-10)13-14(15(25-23-13)16(19,20)21)24-22-12-7-5-11(18)6-8-12/h1-8H,(H,23,25) JUBHQKJYIACFSX-UHFFFAOYSA-N 50344887 3-(4-Chlorophenyl)-4-(2-(4-chlorophenyl)hydrazono)-5-trifuoromethyl)-4H-pyrazole::CHEMBL1780072 Prostaglandin G/H synthase 2 Ovis aries 40000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344887&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54587539 131347823 CHEMBL1780072 ZINC71333201 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642144 FC(F)(F)c1[nH]nc(c1N=Nc1ccc(Br)cc1)-c1ccc(Cl)cc1 InChI=1S/C16H9BrClF3N4/c17-10-3-7-12(8-4-10)22-24-14-13(9-1-5-11(18)6-2-9)23-25-15(14)16(19,20)21/h1-8H,(H,23,25) PGLHQUUZHFYPRO-UHFFFAOYSA-N 50344888 3-(4-Chlorophenyl)-4-(2-(4-bromophenyl)hydrazono)-5-trifuoromethyl)-4H-pyrazole::CHEMBL1780073 Prostaglandin G/H synthase 2 Ovis aries 3000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344888&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54586501 131347824 CHEMBL1780073 ZINC71333428 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642145 [O-][N+](=O)c1ccc(cc1)\[NH+]=N\c1c(n[n-]c1C(F)(F)F)-c1ccc(Cl)cc1 InChI=1S/C16H8ClF3N5O2/c17-10-3-1-9(2-4-10)13-14(15(24-22-13)16(18,19)20)23-21-11-5-7-12(8-6-11)25(26)27/h1-8H/q-1/p+1/b23-21+ FGTMXVGVXKGSHA-XTQSDGFTSA-O 50344889 3-(4-Chlorophenyl)-4-(2-(4-nitrophenyl)hydrazono)-5-trifuoromethyl)-4H-pyrazole::CHEMBL1780074 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344889&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54583598 131347825 CHEMBL1780074 ZINC71333411 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642146 COc1ccc(cc1)N=Nc1c(n[nH]c1C(F)(F)F)-c1ccc(Cl)cc1 InChI=1S/C17H12ClF3N4O/c1-26-13-8-6-12(7-9-13)22-24-15-14(10-2-4-11(18)5-3-10)23-25-16(15)17(19,20)21/h2-9H,1H3,(H,23,25) CFGNKNVPDRHWLV-UHFFFAOYSA-N 50344890 3-(4-Chlorophenyl)-4-(2-(4-methoxyphenyl)hydrazono)-5-trifuoromethyl)-4H-pyrazole::CHEMBL1780075 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344890&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54585526 131347826 CHEMBL1780075 ZINC71332082 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50642147 FC(F)(F)c1[nH]nc(c1N=Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)-c1ccc(Cl)cc1 InChI=1S/C18H8ClF9N4/c19-11-3-1-8(2-4-11)13-14(15(32-30-13)18(26,27)28)31-29-12-6-9(16(20,21)22)5-10(7-12)17(23,24)25/h1-7H,(H,30,32) ZWPDQYNOPRFFFD-UHFFFAOYSA-N 50344891 3-(4-Chlorophenyl)-4-(2-(3,5-bis(trifluoromethyl)phenyl)hydrazono)-5-trifuoromethyl)-4H-pyrazole::CHEMBL1780076 Prostaglandin G/H synthase 2 Ovis aries 45000 ChEMBL 10.1016/j.bmc.2011.04.027 10.7270/Q2JM29ZT 21570309 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; Asiri, YA; Eltahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344891&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54580642 131347827 CHEMBL1780076 ZINC71334836 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664681 CC(=O)Oc1ccccc1-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C18H14F3N3O4S/c1-11(25)28-16-5-3-2-4-14(16)15-10-17(18(19,20)21)23-24(15)12-6-8-13(9-7-12)29(22,26)27/h2-10H,1H3,(H2,22,26,27) LPICFAXAKWQDEP-UHFFFAOYSA-N 50355028 CHEMBL1835472 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355028&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56663369 136361714 CHEMBL1835472 ZINC72128696 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664687 CC(=O)Oc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C18H14F3N3O4S/c1-11(25)28-14-6-2-12(3-7-14)16-10-17(18(19,20)21)23-24(16)13-4-8-15(9-5-13)29(22,26)27/h2-10H,1H3,(H2,22,26,27) JJVIZYYWELEUHH-UHFFFAOYSA-N 50355026 CHEMBL1835055 Prostaglandin G/H synthase 2 Ovis aries 38000 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355026&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56659302 136361712 CHEMBL1835055 ZINC72125186 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664688 CC(=O)Oc1cccc(c1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C18H14F3N3O4S/c1-11(25)28-14-4-2-3-12(9-14)16-10-17(18(19,20)21)23-24(16)13-5-7-15(8-6-13)29(22,26)27/h2-10H,1H3,(H2,22,26,27) NUPUXBPWNYDLDR-UHFFFAOYSA-N 50355027 CHEMBL1835056 Prostaglandin G/H synthase 2 Ovis aries 17100 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355027&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56673152 136361713 CHEMBL1835056 ZINC72125783 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664689 Cc1ccc(-c2cc(nn2-c2ccc(cc2)S(N)(=O)=O)C(F)(F)F)c(O)c1 InChI=1S/C17H14F3N3O3S/c1-10-2-7-13(15(24)8-10)14-9-16(17(18,19)20)22-23(14)11-3-5-12(6-4-11)27(21,25)26/h2-9,24H,1H3,(H2,21,25,26) MGUKBYXVNDLSKG-UHFFFAOYSA-N 50355035 CHEMBL1835473 Prostaglandin G/H synthase 2 Ovis aries 3000 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355035&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56680394 136361721 CHEMBL1835473 ZINC72128697 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664690 CC(=O)Oc1cc(C)ccc1-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C19H16F3N3O4S/c1-11-3-8-15(17(9-11)29-12(2)26)16-10-18(19(20,21)22)24-25(16)13-4-6-14(7-5-13)30(23,27)28/h3-10H,1-2H3,(H2,23,27,28) KWTWBRGTMDMOBY-UHFFFAOYSA-N 50355029 CHEMBL1835474 Prostaglandin G/H synthase 2 Ovis aries 2100 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355029&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56670236 136361715 CHEMBL1835474 ZINC72140931 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664691 Cc1ccc(cc1O)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O3S/c1-10-2-3-11(8-15(10)24)14-9-16(17(18,19)20)22-23(14)12-4-6-13(7-5-12)27(21,25)26/h2-9,24H,1H3,(H2,21,25,26) HFVPKBNDNRVBHU-UHFFFAOYSA-N 50355030 CHEMBL1835475 Prostaglandin G/H synthase 2 Ovis aries 1700 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355030&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56666807 136361716 CHEMBL1835475 ZINC72128516 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664692 CC(=O)Oc1cc(ccc1C)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C19H16F3N3O4S/c1-11-3-4-13(9-17(11)29-12(2)26)16-10-18(19(20,21)22)24-25(16)14-5-7-15(8-6-14)30(23,27)28/h3-10H,1-2H3,(H2,23,27,28) WMFYHRNNFCLTGX-UHFFFAOYSA-N 50355031 CHEMBL1835476 Prostaglandin G/H synthase 2 Ovis aries 7300 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355031&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56683731 136361717 CHEMBL1835476 ZINC72128544 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664693 CC(=O)Oc1cc(F)ccc1-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C18H13F4N3O4S/c1-10(26)29-16-8-11(19)2-7-14(16)15-9-17(18(20,21)22)24-25(15)12-3-5-13(6-4-12)30(23,27)28/h2-9H,1H3,(H2,23,27,28) GUFZZSOUPUDNIF-UHFFFAOYSA-N 50355036 CHEMBL1835477 Prostaglandin G/H synthase 2 Ovis aries 15 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355036&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54753433 136361722 CHEMBL1835477 ZINC72123112 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664694 CC(=O)Oc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C19H15F3N2O4S/c1-12(25)28-15-7-3-13(4-8-15)17-11-18(19(20,21)22)23-24(17)14-5-9-16(10-6-14)29(2,26)27/h3-11H,1-2H3 BGGDLYCFNNWGEW-UHFFFAOYSA-N 50355037 CHEMBL1835478 Prostaglandin G/H synthase 2 Ovis aries 4100 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355037&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56677069 136361723 CHEMBL1835478 ZINC72127768 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664695 CC(=O)Oc1cccc(c1)-c1cc(nn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C19H15F3N2O4S/c1-12(25)28-15-5-3-4-13(10-15)17-11-18(19(20,21)22)23-24(17)14-6-8-16(9-7-14)29(2,26)27/h3-11H,1-2H3 WTCCFVDOATVWAS-UHFFFAOYSA-N 50355032 CHEMBL1835479 Prostaglandin G/H synthase 2 Ovis aries 22300 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355032&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56680395 136361718 CHEMBL1835479 ZINC72124630 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664696 CC(=O)Oc1cc(C)ccc1-c1cc(nn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C20H17F3N2O4S/c1-12-4-9-16(18(10-12)29-13(2)26)17-11-19(20(21,22)23)24-25(17)14-5-7-15(8-6-14)30(3,27)28/h4-11H,1-3H3 FEJHXMDTVILOGN-UHFFFAOYSA-N 50355033 CHEMBL1835481 Prostaglandin G/H synthase 2 Ovis aries 7500 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355033&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56670237 136361719 CHEMBL1835481 ZINC72127770 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664697 CC(=O)Oc1cc(F)ccc1-c1cc(nn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F InChI=1S/C19H14F4N2O4S/c1-11(26)29-17-9-12(20)3-8-15(17)16-10-18(19(21,22)23)24-25(16)13-4-6-14(7-5-13)30(2,27)28/h3-10H,1-2H3 VTEDUDNKJZPEBX-UHFFFAOYSA-N 50355034 CHEMBL1835483 Prostaglandin G/H synthase 2 Ovis aries 18700 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355034&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56666808 136361720 CHEMBL1835483 ZINC72128539 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664698 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664699 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50664701 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1100 ChEMBL 10.1016/j.bmcl.2011.08.053 10.7270/Q2NK3FD8 21890358 Abdur Rahim, M; Praveen Rao, PN; Bhardwaj, A; Kaur, J; Huang, Z; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50717349 Cc1cc(O)c(C2=NN(C(C2)c2ccc(Cl)cc2)c2ccc(cc2)S(N)(=O)=O)c(C)c1Cl InChI=1S/C23H21Cl2N3O3S/c1-13-11-21(29)22(14(2)23(13)25)19-12-20(15-3-5-16(24)6-4-15)28(27-19)17-7-9-18(10-8-17)32(26,30)31/h3-11,20,29H,12H2,1-2H3,(H2,26,30,31) VMRAHOINNVRMNQ-UHFFFAOYSA-N 50363998 CHEMBL1950245 Prostaglandin G/H synthase 2 Ovis aries 87710 ChEMBL 10.1016/j.ejmech.2011.08.015 10.7270/Q2QN6770 22019186 Bano, S; Javed, K; Ahmad, S; Rathish, IG; Singh, S; Alam, MS Jamia Hamdard (Hamdard University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50363998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50363998&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 54613047 136968060 CHEMBL1950245 ZINC82152961 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50717350 Cc1cc(O)c(C2=NN(C(C2)c2ccccc2O)c2ccc(cc2)S(N)(=O)=O)c(C)c1Cl InChI=1S/C23H22ClN3O4S/c1-13-11-21(29)22(14(2)23(13)24)18-12-19(17-5-3-4-6-20(17)28)27(26-18)15-7-9-16(10-8-15)32(25,30)31/h3-11,19,28-29H,12H2,1-2H3,(H2,25,30,31) WXEFPXUPLWBEIJ-UHFFFAOYSA-N 50363999 CHEMBL1950247 Prostaglandin G/H synthase 2 Ovis aries 88210 ChEMBL 10.1016/j.ejmech.2011.08.015 10.7270/Q2QN6770 22019186 Bano, S; Javed, K; Ahmad, S; Rathish, IG; Singh, S; Alam, MS Jamia Hamdard (Hamdard University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50363999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50363999&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56649613 136968061 CHEMBL1950247 ZINC73386555 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50717351 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 360 ChEMBL 10.1016/j.ejmech.2011.08.015 10.7270/Q2QN6770 22019186 Bano, S; Javed, K; Ahmad, S; Rathish, IG; Singh, S; Alam, MS Jamia Hamdard (Hamdard University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832681 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832683 CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(F)c(F)c1 InChI=1S/C16H10F2O3S/c1-22(20,21)13-6-2-11(3-7-13)4-9-16(19)12-5-8-14(17)15(18)10-12/h2-3,5-8,10H,1H3 ZYQKSSGGSWACEA-UHFFFAOYSA-N 22352 1,3-Diarylprop-2-yn-1-one, 13i::1-(3,4-difluorophenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL197573 Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22352&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11544269 49846167 51723 CHEMBL197573 ZINC13683346 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832685 COc1ccc(cc1O)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C17H14O5S/c1-22-17-10-6-13(11-16(17)19)15(18)9-5-12-3-7-14(8-4-12)23(2,20)21/h3-4,6-8,10-11,19H,1-2H3 WJSBSGFLLJDNNO-UHFFFAOYSA-N 22365 1,3-Diarylprop-2-yn-1-one, 23b::1-(3-hydroxy-4-methoxyphenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL196084 Prostaglandin G/H synthase 2 Ovis aries 3200 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22365&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11558987 49846180 51723 CHEMBL196084 ZINC13683388 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832687 CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(F)cc1 InChI=1S/C16H11FO3S/c1-21(19,20)15-9-2-12(3-10-15)4-11-16(18)13-5-7-14(17)8-6-13/h2-3,5-10H,1H3 MLUHCMRZZNXKAQ-UHFFFAOYSA-N 22351 1,3-Diarylprop-2-yn-1-one, 13h::1-(4-fluorophenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL427356 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22351&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11587524 49846166 51723 CHEMBL427356 ZINC13683342 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832689 COc1cccc(c1)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C17H14O4S/c1-21-15-5-3-4-14(12-15)17(18)11-8-13-6-9-16(10-7-13)22(2,19)20/h3-7,9-10,12H,1-2H3 VQAPSMWGGKSMKB-UHFFFAOYSA-N 22355 1,3-Diarylprop-2-yn-1-one, 13l::3-(4-methanesulfonylphenyl)-1-(3-methoxyphenyl)prop-2-yn-1-one::CHEMBL194298 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22355&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11659658 49846170 51723 CHEMBL194298 ZINC13683355 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832699 COc1cc(cc(OC)c1OC)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C19H18O6S/c1-23-17-11-14(12-18(24-2)19(17)25-3)16(20)10-7-13-5-8-15(9-6-13)26(4,21)22/h5-6,8-9,11-12H,1-4H3 QUSHLFKUHGFZFA-UHFFFAOYSA-N 22358 1,3-Diarylprop-2-yn-1-one, 13o::3-(4-methanesulfonylphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-one::CHEMBL194891 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22358&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11675181 49846173 51723 CHEMBL194891 ZINC13683368 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832702 CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccccc1 InChI=1S/C16H12O3S/c1-20(18,19)15-10-7-13(8-11-15)9-12-16(17)14-5-3-2-4-6-14/h2-8,10-11H,1H3 OIHHELVXIPDXIK-UHFFFAOYSA-N 22344 1,3-Diarylprop-2-yn-1-one, 13a::3-(4-methanesulfonylphenyl)-1-phenylprop-2-yn-1-one::CHEMBL193856 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22344&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11231439 49846159 51723 CHEMBL193856 ZINC13683316 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832703 CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1cccc(O)c1 InChI=1S/C16H12O4S/c1-21(19,20)15-8-5-12(6-9-15)7-10-16(18)13-3-2-4-14(17)11-13/h2-6,8-9,11,17H,1H3 SPIXUCBYSFERMW-UHFFFAOYSA-N 22356 1,3-Diarylprop-2-yn-1-one, 13m::1-(3-hydroxyphenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL364739 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22356&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11543953 49846171 51723 CHEMBL364739 ZINC13683360 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832705 CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(cc1)C#N InChI=1S/C17H11NO3S/c1-22(20,21)16-9-4-13(5-10-16)6-11-17(19)15-7-2-14(12-18)3-8-15/h2-5,7-10H,1H3 SOAPFIVAYXWGKD-UHFFFAOYSA-N 22350 1,3-Diarylprop-2-yn-1-one, 13g::4-[3-(4-methanesulfonylphenyl)prop-2-ynoyl]benzonitrile::CHEMBL362923 Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22350&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11688142 49846165 51723 CHEMBL362923 ZINC13683338 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50825611 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 265500 ChEMBL 10.1016/j.bmcl.2005.02.039 10.7270/Q20V8DJD 15780608 Selvam, C; Jachak, SM; Thilagavathi, R; Chakraborti, AK National Institute of Pharmaceutical Education and Research (NIPER) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50825612 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 2050 ChEMBL 10.1016/j.bmcl.2005.02.039 10.7270/Q20V8DJD 15780608 Selvam, C; Jachak, SM; Thilagavathi, R; Chakraborti, AK National Institute of Pharmaceutical Education and Research (NIPER) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832716 CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(cc1)C(F)(F)F InChI=1S/C17H11F3O3S/c1-24(22,23)15-9-2-12(3-10-15)4-11-16(21)13-5-7-14(8-6-13)17(18,19)20/h2-3,5-10H,1H3 GJFAJGZOLWWKBV-UHFFFAOYSA-N 22349 1,3-Diarylprop-2-yn-1-one, 13f::3-(4-methanesulfonylphenyl)-1-[4-(trifluoromethyl)phenyl]prop-2-yn-1-one::CHEMBL194273 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22349&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11508598 49846164 51723 CHEMBL194273 ZINC13683334 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832721 COc1ccc(cc1)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C17H14O4S/c1-21-15-8-6-14(7-9-15)17(18)12-5-13-3-10-16(11-4-13)22(2,19)20/h3-4,6-11H,1-2H3 LMOLTVREAPCOOR-UHFFFAOYSA-N 22353 1,3-Diarylprop-2-yn-1-one, 13j::3-(4-methanesulfonylphenyl)-1-(4-methoxyphenyl)prop-2-yn-1-one::CHEMBL371191 Prostaglandin G/H synthase 2 Ovis aries 31500 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22353&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11370434 49846168 51723 CHEMBL371191 ZINC13683349 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832729 Cc1ccc(cc1)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C17H14O3S/c1-13-3-8-15(9-4-13)17(18)12-7-14-5-10-16(11-6-14)21(2,19)20/h3-6,8-11H,1-2H3 MVEXLQMDJOVCFZ-UHFFFAOYSA-N 22345 1,3-Diarylprop-2-yn-1-one, 13b::3-(4-methanesulfonylphenyl)-1-(4-methylphenyl)prop-2-yn-1-one::CHEMBL194897 Prostaglandin G/H synthase 2 Ovis aries 33000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22345&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11565642 49846160 51723 CHEMBL194897 ZINC13683319 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832730 COc1cc(ccc1O)C(=O)C#Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C17H14O5S/c1-22-17-11-13(6-10-16(17)19)15(18)9-5-12-3-7-14(8-4-12)23(2,20)21/h3-4,6-8,10-11,19H,1-2H3 JTZACODMRDSWHQ-UHFFFAOYSA-N 22364 1,3-Diarylprop-2-yn-1-one, 23a::1-(4-hydroxy-3-methoxyphenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL372548 Prostaglandin G/H synthase 2 Ovis aries 3000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22364&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11645624 49846179 51723 CHEMBL372548 ZINC13683385 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50832732 CS(=O)(=O)c1ccc(cc1)C#CC(=O)c1ccc(O)cc1 InChI=1S/C16H12O4S/c1-21(19,20)15-9-2-12(3-10-15)4-11-16(18)13-5-7-14(17)8-6-13/h2-3,5-10,17H,1H3 NGUFATXOGLRQTH-UHFFFAOYSA-N 22354 1,3-Diarylprop-2-yn-1-one, 13k::1-(4-hydroxyphenyl)-3-(4-methanesulfonylphenyl)prop-2-yn-1-one::CHEMBL194297 Prostaglandin G/H synthase 2 Ovis aries 10000 ChEMBL 10.1016/j.bmcl.2005.07.036 10.7270/Q2RJ4K7N 16143531 Rao, PN; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22354&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11680988 49846169 51723 CHEMBL194297 ZINC13683351 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862931 CS(=O)(=O)c1ccc(\C=C(\C(=O)OCCO[N+]([O-])=O)c2ccccc2)cc1 InChI=1S/C18H17NO7S/c1-27(23,24)16-9-7-14(8-10-16)13-17(15-5-3-2-4-6-15)18(20)25-11-12-26-19(21)22/h2-10,13H,11-12H2,1H3/b17-13+ AOKALBTYQDYDLS-GHRIWEEISA-N 50374768 CHEMBL260539 Prostaglandin G/H synthase 2 Ovis aries 180 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374768&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451297 160853858 CHEMBL260539 ZINC29059971 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862932 CS(=O)(=O)c1ccc(\C=C(\C(O)=O)c2ccc(Br)cc2)cc1 InChI=1S/C16H13BrO4S/c1-22(20,21)14-8-2-11(3-9-14)10-15(16(18)19)12-4-6-13(17)7-5-12/h2-10H,1H3,(H,18,19)/b15-10+ JTFOMMOBIVAERG-XNTDXEJSSA-N 50374769 CHEMBL259402 Prostaglandin G/H synthase 2 Ovis aries 3600 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374769&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451435 160853859 CHEMBL259402 ZINC29060932 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862933 CS(=O)(=O)c1ccc(\C=C(\C(O)=O)c2ccc(F)cc2)cc1 InChI=1S/C16H13FO4S/c1-22(20,21)14-8-2-11(3-9-14)10-15(16(18)19)12-4-6-13(17)7-5-12/h2-10H,1H3,(H,18,19)/b15-10+ PERMQNUWKOEGBE-XNTDXEJSSA-N 50374770 CHEMBL407035 Prostaglandin G/H synthase 2 Ovis aries 36000 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374770&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451433 160853860 CHEMBL407035 ZINC29060923 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862934 COc1ccc(cc1)C(=C/c1ccc(cc1)S(C)(=O)=O)\C(O)=O InChI=1S/C17H16O5S/c1-22-14-7-5-13(6-8-14)16(17(18)19)11-12-3-9-15(10-4-12)23(2,20)21/h3-11H,1-2H3,(H,18,19)/b16-11+ BDTOGQQVLQOSBE-LFIBNONCSA-N 50374771 CHEMBL259401 Prostaglandin G/H synthase 2 Ovis aries 1900 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374771&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451434 160853861 CHEMBL259401 ZINC29060927 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862936 CS(=O)(=O)c1ccc(\C=C(\C(O)=O)c2ccccc2)cc1 InChI=1S/C16H14O4S/c1-21(19,20)14-9-7-12(8-10-14)11-15(16(17)18)13-5-3-2-4-6-13/h2-11H,1H3,(H,17,18)/b15-11+ SGXOPFUROYPPEL-RVDMUPIBSA-N 50374772 CHEMBL405127 Prostaglandin G/H synthase 2 Ovis aries 3000 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374772&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451451 160853862 CHEMBL405127 ZINC29061047 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862945 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862946 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862947 CS(=O)(=O)c1ccc(\C=C(\C(=O)OCCO[N+]([O-])=O)c2ccc(Br)cc2)cc1 InChI=1S/C18H16BrNO7S/c1-28(24,25)16-8-2-13(3-9-16)12-17(14-4-6-15(19)7-5-14)18(21)26-10-11-27-20(22)23/h2-9,12H,10-11H2,1H3/b17-12+ PJTHMBZWJABPOK-SFQUDFHCSA-N 50374775 CHEMBL260841 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374775&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 24939229 160853865 CHEMBL260841 ZINC29059675 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862948 COc1ccc(cc1)C(=C/c1ccc(cc1)S(C)(=O)=O)\C(=O)OCCO[N+]([O-])=O InChI=1S/C19H19NO8S/c1-26-16-7-5-15(6-8-16)18(19(21)27-11-12-28-20(22)23)13-14-3-9-17(10-4-14)29(2,24)25/h3-10,13H,11-12H2,1-2H3/b18-13+ MWDBEBHNBQDZDR-QGOAFFKASA-N 50374774 CHEMBL405095 Prostaglandin G/H synthase 2 Ovis aries 1400 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374774&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451279 160853864 CHEMBL405095 ZINC29059846 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862951 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50862952 CS(=O)(=O)c1ccc(\C=C(\C(=O)OCCO[N+]([O-])=O)c2ccc(F)cc2)cc1 InChI=1S/C18H16FNO7S/c1-28(24,25)16-8-2-13(3-9-16)12-17(14-4-6-15(19)7-5-14)18(21)26-10-11-27-20(22)23/h2-9,12H,10-11H2,1H3/b17-12+ UJPPTJDIXOBGGH-SFQUDFHCSA-N 50374773 CHEMBL261054 Prostaglandin G/H synthase 2 Ovis aries 2800 ChEMBL 10.1016/j.bmc.2007.12.006 10.7270/Q2DN45XK 18096394 Abdellatif, KR; Chowdhury, MA; Dong, Y; Chen, QH; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374773&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451262 160853863 CHEMBL261054 ZINC29059686 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872350 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 1710000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872352 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 164000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872357 C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-24,26-29H,1H3/t7-,15-,17+,18+,21-/m0/s1 XHIUPRGKXRAZCR-HQBVPOQASA-N 84978 Quercitrin::cid_5280459 Prostaglandin G/H synthase 2 Ovis aries >2000000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84978&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5280459 136351078 17558 C02757 ZINC04175638 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872359 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries >5000000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872360 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 370000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872367 C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-24,26-29H,1H3/t7-,15-,17+,18+,21-/m0/s1 XHIUPRGKXRAZCR-HQBVPOQASA-N 84978 Quercitrin::cid_5280459 Prostaglandin G/H synthase 2 Ovis aries >2000000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84978&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5280459 136351078 17558 C02757 ZINC04175638 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872369 CS(=O)(=O)Nc1ccc(cc1OC1CCCCC1)[N+]([O-])=O InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 KTDZCOWXCWUPEO-UHFFFAOYSA-N 50029593 CHEMBL7162::N-(2-(cyclohexyloxy)-4-nitrophenyl)methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide(NS-398)::N-[2-(cyclohexyloxy)-4-nitrophenyl]methane sulfonamide::N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulfonamide::N-{2-(cyclohexyloxy)-4-[hydroxy(oxido)amino]phenyl}methanesulfonamide::NS-398::NS398 Prostaglandin G/H synthase 2 Ovis aries 53000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029593&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NS4 3QMO 4553 103938654 73458 CHEMBL7162 ZINC03791739 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872370 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries >5000000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872371 COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 CMWTZPSULFXXJA-VIFPVBQESA-N 50339185 (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid::(S)-2-(6-Methoxy-naphthalen-2-yl)-propionic acid::(S)-2-(6-methoxynaphthalen-2-yl)propanoic acid::(S)-naproxen::2-(6-Methoxy-naphthalen-2-yl)-propionic acid::2-(6-Methoxy-naphthalen-2-yl)-propionic acid(naproxen)::2-(6-methoxy-2-naphthyl)propanoic acid::2-(6-methoxynaphthalen-2-yl)propanoic acid::Aleve::Anaprox::CHEMBL154::Ec-naprosyn::Equiproxen::Naprelan::Naprosyn::Naproxen::Naproxen2-(6-Methoxy-naphthalen-2-yl)-propionic acid::RS-3540::S-NAPROXEN::US11459295, Compound S-Naproxen (1)::naproxene Prostaglandin G/H synthase 2 Ovis aries 1015000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339185&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NPS 3NT1,4PO0,4OT2,2VDB,4JQ1,3R58,5DBY,4OR0,4ZBR,4FJP 156391 125089287 7476 CHEMBL154 DB00788 5230 C01517 ZINC00105216 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872372 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1030000 ChEMBL 10.1021/np970343j 10.7270/Q2JS9RBH 9461646 Noreen, Y; Ringbom, T; Perera, P; Danielson, H; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872378 COc1cc(cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1OC)-c1coc2cc(O)cc(O)c2c1=O InChI=1S/C23H24O12/c1-31-14-3-9(11-8-33-13-6-10(25)5-12(26)17(13)18(11)27)4-15(22(14)32-2)34-23-21(30)20(29)19(28)16(7-24)35-23/h3-6,8,16,19-21,23-26,28-30H,7H2,1-2H3/t16-,19-,20+,21-,23-/m1/s1 PIUYQFXGNHWGBD-JTLUYSSBSA-N 50250508 5-hydroxy-7,4',5'-trimethoxyisoflavone 3'-O-beta-D-glucoside::CHEMBL462878 Prostaglandin G/H synthase 2 Ovis aries 1200000 ChEMBL 10.1021/np970198+ 10.7270/Q2F190NX 9461647 Noreen, Y; el-Seedi, H; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250508&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44566588 104104232 CHEMBL462878 C03400 ZINC40873953 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50872379 COc1cc(cc(O)c1OC)-c1coc2cc(O)cc(O)c2c1=O InChI=1S/C17H14O7/c1-22-14-4-8(3-12(20)17(14)23-2)10-7-24-13-6-9(18)5-11(19)15(13)16(10)21/h3-7,18-20H,1-2H3 LVBRSTWDERQTLT-UHFFFAOYSA-N 50250509 5,3'-dihydroxy-7,4',5'-trimethoxyisoflavone::CHEMBL504481 Prostaglandin G/H synthase 2 Ovis aries 900000 ChEMBL 10.1021/np970198+ 10.7270/Q2F190NX 9461647 Noreen, Y; el-Seedi, H; Perera, P; Bohlin, L Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250509&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44566589 104104233 CHEMBL504481 ZINC40846222 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864240 NS(=O)(=O)c1ccc(cc1)C#Cc1ccccn1 InChI=1S/C13H10N2O2S/c14-18(16,17)13-8-5-11(6-9-13)4-7-12-3-1-2-10-15-12/h1-3,5-6,8-10H,(H2,14,16,17) GZRBQSAJFPOMOT-UHFFFAOYSA-N 50375395 CHEMBL265444 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375395&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452471 160854485 CHEMBL265444 ZINC29124035 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864256 CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 RZJQGNCSTQAWON-UHFFFAOYSA-N 22369 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one::CHEMBL122::MK 0966::Rofecoxib::US11478464, Compound Rofecoxib Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search RCX 5KIR 5090 49846184 8887 CHEMBL122 DB00533 2893 C07590 ZINC00007455 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864257 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864258 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864259 Cc1cccnc1C#Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C15H13NO2S/c1-12-4-3-11-16-15(12)10-7-13-5-8-14(9-6-13)19(2,17)18/h3-6,8-9,11H,1-2H3 NZHNYRIYMSYVMQ-UHFFFAOYSA-N 50375396 CHEMBL407568 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375396&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452383 160854486 CHEMBL407568 ZINC29123781 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864260 CS(=O)(=O)c1ccc(cc1)C#Cc1cccnc1 InChI=1S/C14H11NO2S/c1-18(16,17)14-8-6-12(7-9-14)4-5-13-3-2-10-15-11-13/h2-3,6-11H,1H3 LIQIAGAWOFOYKG-UHFFFAOYSA-N 50375397 CHEMBL262849 Prostaglandin G/H synthase 2 Ovis aries 40 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375397&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 25099141 160854487 CHEMBL262849 ZINC29123821 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864261 CS(=O)(=O)c1ccc(cc1)C#Cc1ccccn1 InChI=1S/C14H11NO2S/c1-18(16,17)14-9-6-12(7-10-14)5-8-13-4-2-3-11-15-13/h2-4,6-7,9-11H,1H3 NRQIPDCRWJKDSJ-UHFFFAOYSA-N 50375398 CHEMBL408370 Prostaglandin G/H synthase 2 Ovis aries 330 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375398&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452400 160854488 CHEMBL408370 ZINC29123819 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864262 CS(=O)(=O)c1cccc(c1)C#Cc1ccncc1 InChI=1S/C14H11NO2S/c1-18(16,17)14-4-2-3-13(11-14)6-5-12-7-9-15-10-8-12/h2-4,7-11H,1H3 QXVFOSASOGEQBR-UHFFFAOYSA-N 50375399 CHEMBL262852 Prostaglandin G/H synthase 2 Ovis aries 320 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375399&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452403 160854489 CHEMBL262852 ZINC29123825 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864263 CS(=O)(=O)c1cccc(c1)C#Cc1cccnc1 InChI=1S/C14H11NO2S/c1-18(16,17)14-6-2-4-12(10-14)7-8-13-5-3-9-15-11-13/h2-6,9-11H,1H3 TWNBFYCRGGZRDI-UHFFFAOYSA-N 50375400 CHEMBL262851 Prostaglandin G/H synthase 2 Ovis aries 31600 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375400&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452402 160854490 CHEMBL262851 ZINC29123823 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864264 CS(=O)(=O)c1cccc(c1)C#Cc1ccccn1 InChI=1S/C14H11NO2S/c1-18(16,17)14-7-4-5-12(11-14)8-9-13-6-2-3-10-15-13/h2-7,10-11H,1H3 HEAFZXABQFXKMB-UHFFFAOYSA-N 50375401 CHEMBL260943 Prostaglandin G/H synthase 2 Ovis aries 200 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375401&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452428 160854491 CHEMBL260943 ZINC29123897 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864265 Cc1cccnc1C#Cc1ccccc1S(C)(=O)=O InChI=1S/C15H13NO2S/c1-12-6-5-11-16-14(12)10-9-13-7-3-4-8-15(13)19(2,17)18/h3-8,11H,1-2H3 LFQPWZLFQKDVHB-UHFFFAOYSA-N 50375402 CHEMBL404927 Prostaglandin G/H synthase 2 Ovis aries 420 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375402&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452427 160854492 CHEMBL404927 ZINC29123896 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864266 CS(=O)(=O)c1ccccc1C#Cc1ccncc1 InChI=1S/C14H11NO2S/c1-18(16,17)14-5-3-2-4-13(14)7-6-12-8-10-15-11-9-12/h2-5,8-11H,1H3 VNELCQYKANNPCF-UHFFFAOYSA-N 50375403 CHEMBL260944 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375403&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452430 160854493 CHEMBL260944 ZINC29123899 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864267 CS(=O)(=O)c1ccccc1C#Cc1cccnc1 InChI=1S/C14H11NO2S/c1-18(16,17)14-7-3-2-6-13(14)9-8-12-5-4-10-15-11-12/h2-7,10-11H,1H3 RQNKLZMHVJIRLX-UHFFFAOYSA-N 50375404 CHEMBL265185 Prostaglandin G/H synthase 2 Ovis aries 31600 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375404&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452449 160854494 CHEMBL265185 ZINC29123959 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864268 CS(=O)(=O)c1ccccc1C#Cc1ccccn1 InChI=1S/C14H11NO2S/c1-18(16,17)14-8-3-2-6-12(14)9-10-13-7-4-5-11-15-13/h2-8,11H,1H3 KVZRFZQSUUZUIV-UHFFFAOYSA-N 50375405 CHEMBL404928 Prostaglandin G/H synthase 2 Ovis aries 210 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375405&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452451 160854495 CHEMBL404928 ZINC29123961 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864269 Cc1cccnc1C#Cc1ccc(cc1)S(N)(=O)=O InChI=1S/C14H12N2O2S/c1-11-3-2-10-16-14(11)9-6-12-4-7-13(8-5-12)19(15,17)18/h2-5,7-8,10H,1H3,(H2,15,17,18) UXYCXVOSKMVQHR-UHFFFAOYSA-N 50375406 CHEMBL259429 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375406&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452453 160854496 CHEMBL259429 ZINC29123971 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50864270 NS(=O)(=O)c1ccc(cc1)C#Cc1ccncc1 InChI=1S/C13H10N2O2S/c14-18(16,17)13-5-3-11(4-6-13)1-2-12-7-9-15-10-8-12/h3-10H,(H2,14,16,17) WAURLAKEIUZSMJ-UHFFFAOYSA-N 50375407 CHEMBL406989 Prostaglandin G/H synthase 2 Ovis aries 26800 ChEMBL 10.1016/j.bmc.2007.11.003 10.7270/Q2VH5PPP 18023187 Chowdhury, MA; Dong, Y; Chen, QH; Abdellatif, KR; Knaus, EE University of Alberta http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375407&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44452472 160854497 CHEMBL406989 ZINC29124037 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867798 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) VUSRFTDIRYHHTA-UHFFFAOYSA-N 50376853 CHEMBL258986 Prostaglandin G/H synthase 2 Ovis aries 1400 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376853&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9866143 160855936 CHEMBL258986 ZINC03973408 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867820 NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1c[nH]c2ccccc12)C(F)(F)F InChI=1S/C18H13F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-10,23H,(H2,22,26,27) WKTKZNZWBRSPNY-UHFFFAOYSA-N 50376854 CHEMBL261143::US8741944, 44 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376854&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10409042 160855937 CHEMBL261143 ZINC29060968 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867821 Nc1cccc2c(c[nH]c12)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C18H16F3N5O2S/c19-18(20,21)16-8-15(13-9-24-17-12(13)2-1-3-14(17)22)26(25-16)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8,22H2,(H2,23,27,28) XFZUDWXLTJPSDK-UHFFFAOYSA-N 50376855 CHEMBL412315 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376855&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451439 160855938 CHEMBL412315 ZINC29060962 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867822 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2c(cccc12)[N+]([O-])=O)C(F)(F)F InChI=1S/C18H14F3N5O4S/c19-18(20,21)16-8-15(13-9-23-17-12(13)2-1-3-14(17)26(27)28)25(24-16)10-4-6-11(7-5-10)31(22,29)30/h1-7,9,15,23H,8H2,(H2,22,29,30) DKVMUSUBWRUPMT-UHFFFAOYSA-N 50376856 CHEMBL259881 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376856&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451440 160855939 CHEMBL259881 ZINC29060984 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867823 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)C(O)=O)C(F)(F)F InChI=1S/C19H15F3N4O4S/c20-19(21,22)17-8-16(14-9-24-15-6-1-10(18(27)28)7-13(14)15)26(25-17)11-2-4-12(5-3-11)31(23,29)30/h1-7,9,16,24H,8H2,(H,27,28)(H2,23,29,30) HLYJTUSOTOYTMX-UHFFFAOYSA-N 50376857 CHEMBL412286 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376857&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451455 160855940 CHEMBL412286 ZINC29061094 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867824 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)[N+]([O-])=O)C(F)(F)F InChI=1S/C18H14F3N5O4S/c19-18(20,21)17-8-16(14-9-23-15-6-3-11(26(27)28)7-13(14)15)25(24-17)10-1-4-12(5-2-10)31(22,29)30/h1-7,9,16,23H,8H2,(H2,22,29,30) NBBMIJGROOZDFJ-UHFFFAOYSA-N 50376858 CHEMBL265200 Prostaglandin G/H synthase 2 Ovis aries 57200 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376858&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451454 160855941 CHEMBL265200 ZINC29061085 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867825 Nc1ccc2c(c[nH]c2c1)C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C18H16F3N5O2S/c19-18(20,21)17-8-16(14-9-24-15-7-10(22)1-6-13(14)15)26(25-17)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8,22H2,(H2,23,27,28) NWCCEPXMALICKQ-UHFFFAOYSA-N 50376859 CHEMBL408971 Prostaglandin G/H synthase 2 Ovis aries 7500 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451467 160855942 CHEMBL408971 ZINC29061248 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867826 COc1cccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c12 InChI=1S/C19H17F3N4O3S/c1-29-16-4-2-3-14-18(16)13(10-24-14)15-9-17(19(20,21)22)25-26(15)11-5-7-12(8-6-11)30(23,27)28/h2-8,10,15,24H,9H2,1H3,(H2,23,27,28) TTZOLICNMMLGGH-UHFFFAOYSA-N 50376860 CHEMBL411032 Prostaglandin G/H synthase 2 Ovis aries 8700 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376860&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451468 160855943 CHEMBL411032 ZINC29061265 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867827 Cc1[nH]c2cc(Cl)ccc2c1C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C19H16ClF3N4O2S/c1-10-18(14-7-2-11(20)8-15(14)25-10)16-9-17(19(21,22)23)26-27(16)12-3-5-13(6-4-12)30(24,28)29/h2-8,16,25H,9H2,1H3,(H2,24,28,29) GOTJJVYMGLJGDI-UHFFFAOYSA-N 50376861 CHEMBL411719 Prostaglandin G/H synthase 2 Ovis aries 6000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376861&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451479 160855944 CHEMBL411719 ZINC29061370 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867828 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(ccc12)[N+]([O-])=O)C(F)(F)F InChI=1S/C18H14F3N5O4S/c19-18(20,21)17-8-16(14-9-23-15-7-11(26(27)28)3-6-13(14)15)25(24-17)10-1-4-12(5-2-10)31(22,29)30/h1-7,9,16,23H,8H2,(H2,22,29,30) HQFMQWRLYXYQNZ-UHFFFAOYSA-N 50376862 CHEMBL258988 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376862&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451481 160855945 CHEMBL258988 ZINC29061386 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867829 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(ccc12)C#N)C(F)(F)F InChI=1S/C19H14F3N5O2S/c20-19(21,22)18-8-17(15-10-25-16-7-11(9-23)1-6-14(15)16)27(26-18)12-2-4-13(5-3-12)30(24,28)29/h1-7,10,17,25H,8H2,(H2,24,28,29) ZBPAMZHJZRFIDC-UHFFFAOYSA-N 50376863 CHEMBL263383 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376863&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451488 160855946 CHEMBL263383 ZINC29061492 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867830 Nc1cccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c12 InChI=1S/C18H16F3N5O2S/c19-18(20,21)16-8-15(12-9-24-14-3-1-2-13(22)17(12)14)26(25-16)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8,22H2,(H2,23,27,28) SQXDTRVNXAYNGU-UHFFFAOYSA-N 50376864 CHEMBL263640 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376864&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451490 160855947 CHEMBL263640 ZINC29061507 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867831 Nc1ccc2[nH]cc(C3CC(=NN3c3ccc(cc3)S(N)(=O)=O)C(F)(F)F)c2c1 InChI=1S/C18H16F3N5O2S/c19-18(20,21)17-8-16(14-9-24-15-6-1-10(22)7-13(14)15)26(25-17)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8,22H2,(H2,23,27,28) BRHFADVAYPHTRK-UHFFFAOYSA-N 50376865 CHEMBL412100 Prostaglandin G/H synthase 2 Ovis aries 850 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376865&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451251 160855948 CHEMBL412100 ZINC29059595 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867832 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(Br)ccc12)C(F)(F)F InChI=1S/C18H14BrF3N4O2S/c19-10-1-6-13-14(9-24-15(13)7-10)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28) BFOQXQJHELRPCL-UHFFFAOYSA-N 50376866 CHEMBL261067 Prostaglandin G/H synthase 2 Ovis aries 4400 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376866&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451268 160855949 CHEMBL261067 ZINC29059756 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867833 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(cc12)C#N)C(F)(F)F InChI=1S/C19H14F3N5O2S/c20-19(21,22)18-8-17(15-10-25-16-6-1-11(9-23)7-14(15)16)27(26-18)12-2-4-13(5-3-12)30(24,28)29/h1-7,10,17,25H,8H2,(H2,24,28,29) NHUSSNSETPOHAT-UHFFFAOYSA-N 50376867 CHEMBL412054 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376867&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451267 160855950 CHEMBL412054 ZINC29059744 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867834 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2c(Cl)cccc12)C(F)(F)F InChI=1S/C18H14ClF3N4O2S/c19-14-3-1-2-12-13(9-24-17(12)14)15-8-16(18(20,21)22)25-26(15)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8H2,(H2,23,27,28) NDGPUMDPTVGJCG-UHFFFAOYSA-N 50376868 CHEMBL261429 Prostaglandin G/H synthase 2 Ovis aries 3900 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376868&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451247 160855951 CHEMBL261429 ZINC29059569 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867835 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(Cl)ccc12)C(F)(F)F InChI=1S/C18H14ClF3N4O2S/c19-10-1-6-13-14(9-24-15(13)7-10)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28) OXJNPSXOCUYXDJ-UHFFFAOYSA-N 50376869 CHEMBL261255 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376869&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451302 160855952 CHEMBL261255 ZINC29060016 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867836 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2cc(F)ccc12)C(F)(F)F InChI=1S/C18H14F4N4O2S/c19-10-1-6-13-14(9-24-15(13)7-10)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28) QVBQBEIKCJDTGR-UHFFFAOYSA-N 50376870 CHEMBL261474 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376870&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451304 160855953 CHEMBL261474 ZINC29060031 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867837 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(Cl)cc12)C(F)(F)F InChI=1S/C18H14ClF3N4O2S/c19-10-1-6-15-13(7-10)14(9-24-15)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28) LAKINFLQZJZQCE-UHFFFAOYSA-N 50376871 CHEMBL409268 Prostaglandin G/H synthase 2 Ovis aries 38700 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376871&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451328 160855954 CHEMBL409268 ZINC29060191 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867838 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccc(F)cc12)C(F)(F)F InChI=1S/C18H14F4N4O2S/c19-10-1-6-15-13(7-10)14(9-24-15)16-8-17(18(20,21)22)25-26(16)11-2-4-12(5-3-11)29(23,27)28/h1-7,9,16,24H,8H2,(H2,23,27,28) NZUVPFWKEMFFNG-UHFFFAOYSA-N 50376872 CHEMBL260691 Prostaglandin G/H synthase 2 Ovis aries 13500 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376872&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451327 160855955 CHEMBL260691 ZINC29060181 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867842 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2c(Cl)cccc12)C(F)(F)F InChI=1S/C18H14ClF3N4O2S/c19-14-3-1-2-12-13(9-24-17(12)14)15-8-16(18(20,21)22)25-26(15)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8H2,(H2,23,27,28) NDGPUMDPTVGJCG-UHFFFAOYSA-N 50376868 CHEMBL261429 Prostaglandin G/H synthase 2 Ovis aries 3900 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376868&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451247 160855951 CHEMBL261429 ZINC29059569 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867843 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2c(Cl)cccc12)C(F)(F)F InChI=1S/C18H14ClF3N4O2S/c19-14-3-1-2-12-13(9-24-17(12)14)15-8-16(18(20,21)22)25-26(15)10-4-6-11(7-5-10)29(23,27)28/h1-7,9,15,24H,8H2,(H2,23,27,28) NDGPUMDPTVGJCG-UHFFFAOYSA-N 50376868 CHEMBL261429 Prostaglandin G/H synthase 2 Ovis aries 84000 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376868&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44451247 160855951 CHEMBL261429 ZINC29059569 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867844 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) VUSRFTDIRYHHTA-UHFFFAOYSA-N 50376853 CHEMBL258986 Prostaglandin G/H synthase 2 Ovis aries 1400 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376853&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9866143 160855936 CHEMBL258986 ZINC03973408 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867846 NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1c[nH]c2ccccc12)C(F)(F)F InChI=1S/C18H15F3N4O2S/c19-18(20,21)17-9-16(14-10-23-15-4-2-1-3-13(14)15)25(24-17)11-5-7-12(8-6-11)28(22,26)27/h1-8,10,16,23H,9H2,(H2,22,26,27) VUSRFTDIRYHHTA-UHFFFAOYSA-N 50376853 CHEMBL258986 Prostaglandin G/H synthase 2 Ovis aries 850 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376853&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9866143 160855936 CHEMBL258986 ZINC03973408 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50867819 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 1710 ChEMBL 10.1016/j.bmc.2008.01.047 10.7270/Q2S46SV4 18272371 Reddy, MV; Billa, VK; Pallela, VR; Mallireddigari, MR; Boominathan, R; Gabriel, JL; Reddy, EP Temple University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905755 COc1cc(cc2OCOc12)C1C(C)C2(OC)C=C(CC=C)C(=O)C1(OC)C2O InChI=1S/C22H26O7/c1-6-7-13-10-21(26-4)12(2)17(22(27-5,19(13)23)20(21)24)14-8-15(25-3)18-16(9-14)28-11-29-18/h6,8-10,12,17,20,24H,1,7,11H2,2-5H3 WEUKJHJYSZGNIC-UHFFFAOYSA-N 50378548 CINERIN C Prostaglandin G/H synthase 2 Ovis aries 356000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378548&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56674808 160857631 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905756 COc1cc(cc2OCOc12)[C@@H]1[C@@H](C)[C@@]2(OC)C=C(CC=C)[C@H](O)[C@]1(OC)C2=O InChI=1S/C22H26O7/c1-6-7-13-10-21(26-4)12(2)17(22(27-5,19(13)23)20(21)24)14-8-15(25-3)18-16(9-14)28-11-29-18/h6,8-10,12,17,19,23H,1,7,11H2,2-5H3/t12-,17+,19+,21+,22+/m1/s1 XLIOFFLNGANYEP-RDKBRGHYSA-N 50303135 (7S,8R,2'R,3'S,5'R)-Delta(8')-2'-hydroxy-5,5'-dimethoxy-3,4-methylenedioxy-2',3',4',5'-tetrahydro-4'-oxo-7.3',8.5'-neolignan::CHEMBL558110::Cinerin D Prostaglandin G/H synthase 2 Ovis aries 92100 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303135&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45273291 104157496 CHEMBL558110 ZINC45242050 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905757 CO[C@@]12C=C(CC=C)C(=O)[C@H]([C@H]1O)[C@@H]([C@H]2C)c1ccc2OCOc2c1 InChI=1S/C20H22O5/c1-4-5-13-9-20(23-3)11(2)16(17(18(13)21)19(20)22)12-6-7-14-15(8-12)25-10-24-14/h4,6-9,11,16-17,19,22H,1,5,10H2,2-3H3/t11-,16+,17-,19-,20-/m1/s1 ARFBOYDNJXQGTO-IXYCQQMVSA-N 50303136 CHEMBL585724::Ocophylol A Prostaglandin G/H synthase 2 Ovis aries 312000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303136&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487110 104157497 CHEMBL585724 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905758 COc1ccc(cc1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@H]2O InChI=1S/C21H26O5/c1-6-7-14-11-21(26-5)12(2)17(18(19(14)22)20(21)23)13-8-9-15(24-3)16(10-13)25-4/h6,8-12,17-18,20,23H,1,7H2,2-5H3/t12-,17+,18-,20-,21-/m1/s1 YYEUHNBQISBESB-VVUBONQESA-N 50303137 CHEMBL583036::Ocophylol B Prostaglandin G/H synthase 2 Ovis aries 288000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303137&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487111 104157498 CHEMBL583036 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905759 COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@H]2O InChI=1S/C22H28O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-18,21,24H,1,8H2,2-6H3/t12-,17+,18-,21-,22-/m1/s1 OXBOQKXJZRJDAW-UXPMNEGVSA-N 50303138 CHEMBL570318::Ocophylol C Prostaglandin G/H synthase 2 Ovis aries 245000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303138&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487119 104157499 CHEMBL570318 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905761 COc1cc(cc(OC)c1OC)[C@H]1[C@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@]1(OC)[C@@H]2O InChI=1S/C23H30O7/c1-8-9-14-12-22(29-6)13(2)18(23(30-7,20(14)24)21(22)25)15-10-16(26-3)19(28-5)17(11-15)27-4/h8,10-13,18,21,25H,1,9H2,2-7H3/t13-,18+,21+,22+,23-/m0/s1 IKLPDXKPWBONDW-GAGXKEPLSA-N 50303140 CHEMBL571892::Nectamazin B Prostaglandin G/H synthase 2 Ovis aries 255000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303140&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487121 104157501 CHEMBL571892 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905762 COc1cc(cc(OC)c1OC)[C@H]1[C@H](C)[C@]2(OC)C=C(CC=C)[C@H](O)[C@]1(OC)[C@H]2O InChI=1S/C23H32O7/c1-8-9-14-12-22(29-6)13(2)18(23(30-7,20(14)24)21(22)25)15-10-16(26-3)19(28-5)17(11-15)27-4/h8,10-13,18,20-21,24-25H,1,9H2,2-7H3/t13-,18+,20-,21-,22+,23-/m0/s1 OHVTXDBRSOSKKO-BHIPVSGSSA-N 50303141 CHEMBL570290::Nectamazin C Prostaglandin G/H synthase 2 Ovis aries 6830 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303141&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487137 104157502 CHEMBL570290 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905763 COc1ccc(cc1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)[C@@H]1[C@@H]2O InChI=1S/C21H26O5/c1-6-7-14-11-21(26-5)12(2)17(18(19(14)22)20(21)23)13-8-9-15(24-3)16(10-13)25-4/h6,8-12,17-18,20,23H,1,7H2,2-5H3/t12-,17+,18-,20+,21-/m1/s1 YYEUHNBQISBESB-LOPMHCFQSA-N 50303142 CHEMBL571615::Kadsurenin C Prostaglandin G/H synthase 2 Ovis aries 312000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303142&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487142 104157503 CHEMBL571615 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905764 COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)C(=O)C1C2=O InChI=1S/C22H26O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-18H,1,8H2,2-6H3/t12-,17+,18?,22-/m1/s1 FLIHMBQDBZWUAD-VQNGQWKISA-N 50303143 4'-oxo-macrophyllin B::CHEMBL584539 Prostaglandin G/H synthase 2 Ovis aries 844000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303143&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487143 104157504 CHEMBL584539 ZINC45316217 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905765 COc1cc(cc(OC)c1OC)[C@@H]1[C@@H](C)[C@]2(OC)C=C(CC=C)[C@@H](O)C1C2=O InChI=1S/C22H28O6/c1-7-8-13-11-22(28-6)12(2)17(18(19(13)23)21(22)24)14-9-15(25-3)20(27-5)16(10-14)26-4/h7,9-12,17-19,23H,1,8H2,2-6H3/t12-,17+,18?,19-,22-/m1/s1 NWXSUVZITFIXOL-FXNKJGLGSA-N 50303144 CHEMBL585912::Macrophyllin B Prostaglandin G/H synthase 2 Ovis aries 65400 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303144&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487148 104157505 CHEMBL585912 ZINC45335023 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905766 C[C@@H]1[C@H](C2[C@H](O)[C@@]1(CC=C)C=C(CC=C)C2=O)c1ccc2OCOc2c1 InChI=1S/C22H24O4/c1-4-6-15-11-22(9-5-2)13(3)18(19(20(15)23)21(22)24)14-7-8-16-17(10-14)26-12-25-16/h4-5,7-8,10-11,13,18-19,21,24H,1-2,6,9,12H2,3H3/t13-,18+,19?,21+,22+/m1/s1 IELYWLBCFOCUNW-KUXMWZRESA-N 50303145 2'-epi-guianin::CHEMBL570978 Prostaglandin G/H synthase 2 Ovis aries 326000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303145&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487149 104157506 CHEMBL570978 ZINC45258238 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905767 COc1cc(CC=C)cc2cc(oc12)-c1ccc2OCOc2c1 InChI=1S/C19H16O4/c1-3-4-12-7-14-10-16(23-19(14)18(8-12)20-2)13-5-6-15-17(9-13)22-11-21-15/h3,5-10H,1,4,11H2,2H3 QHQQIGTXXBIMFB-UHFFFAOYSA-N 50303146 CHEMBL571199::Neolignan 9-nor-7,8-dehydro-isolicarin B Prostaglandin G/H synthase 2 Ovis aries 3320 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303146&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11243755 104157507 CHEMBL571199 ZINC13341310 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905768 COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc2OCOc2c1 InChI=1S/C20H20O4/c1-4-5-13-8-15-12(2)19(24-20(15)18(9-13)21-3)14-6-7-16-17(10-14)23-11-22-16/h4-10,12,19H,11H2,1-3H3/b5-4+/t12-,19-/m0/s1 DMMQXURQRMNSBM-NSWCWGQASA-N 50303147 (-)-licarin B::CHEMBL578403 Prostaglandin G/H synthase 2 Ovis aries 25600 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303147&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10860310 104157508 CHEMBL578403 ZINC05554720 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905769 COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc2OCOc2c1 InChI=1S/C20H20O4/c1-4-5-13-8-15-12(2)19(24-20(15)18(9-13)21-3)14-6-7-16-17(10-14)23-11-22-16/h4-10,12,19H,11H2,1-3H3/b5-4+/t12-,19-/m1/s1 DMMQXURQRMNSBM-YZAYTREXSA-N 50303148 (+)-licarin B::CHEMBL259386::licarine B Prostaglandin G/H synthase 2 Ovis aries 52100 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303148&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6441061 104157509 CHEMBL259386 ZINC01587485 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905770 COc1cc(\C=C\C)cc2[C@H](C)[C@H](Oc12)c1ccc(O)c(OC)c1 InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3/b6-5+/t12-,19-/m0/s1 ITDOFWOJEDZPCF-FNINDUDTSA-N 50303149 (-)-licarin A::CHEMBL463526::Licarin A Prostaglandin G/H synthase 2 Ovis aries 32100 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303149&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5281836 104157510 CHEMBL463526 C10650 ZINC04098822 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905771 COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc(O)c(OC)c1 InChI=1S/C20H22O4/c1-5-6-13-9-15-12(2)19(24-20(15)18(10-13)23-4)14-7-8-16(21)17(11-14)22-3/h5-12,19,21H,1-4H3/b6-5+/t12-,19-/m1/s1 ITDOFWOJEDZPCF-OTBILJLCSA-N 50303150 (+)-licarin A::CHEMBL259731::licarin A::licarine A Prostaglandin G/H synthase 2 Ovis aries 66400 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303150&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6442393 104157511 CHEMBL259731 ZINC00900152 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905772 COc1cc(cc(OC)c1OC)[C@H]1OC2=CC(=O)C(CC=C)=C[C@]2(OC)[C@@H]1C InChI=1S/C22H26O6/c1-7-8-14-12-22(27-6)13(2)20(28-19(22)11-16(14)23)15-9-17(24-3)21(26-5)18(10-15)25-4/h7,9-13,20H,1,8H2,2-6H3/t13-,20+,22+/m1/s1 MRRHZTMSIVTFSK-XOJPMGEXSA-N 50303151 CHEMBL570291::Mirandin A Prostaglandin G/H synthase 2 Ovis aries 126000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303151&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487138 104157512 CHEMBL570291 ZINC14594410 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905773 COc1cc(C=O)cc2c(C)c(oc12)-c1ccc2OCOc2c1 InChI=1S/C18H14O5/c1-10-13-5-11(8-19)6-16(20-2)18(13)23-17(10)12-3-4-14-15(7-12)22-9-21-14/h3-8H,9H2,1-2H3 HCCYBFOBGKSPJH-UHFFFAOYSA-N 50303152 CHEMBL571616::Ocophyllals A Prostaglandin G/H synthase 2 Ovis aries 16800 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303152&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44470605 104157513 CHEMBL571616 ZINC45285978 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905774 COc1cc(cc(OC)c1OC)-c1oc2c(OC)cc(C=O)cc2c1C InChI=1S/C20H20O6/c1-11-14-6-12(10-21)7-15(22-2)19(14)26-18(11)13-8-16(23-3)20(25-5)17(9-13)24-4/h6-10H,1-5H3 ABGNFLATGXMICB-UHFFFAOYSA-N 50303153 CHEMBL571617::Ocophyllals B Prostaglandin G/H synthase 2 Ovis aries 12700 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303153&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44470606 104157514 CHEMBL571617 ZINC45285980 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905775 COc1cc(\C=C\C)cc2[C@@H](C)[C@@H](Oc12)c1ccc(OC)c(OC)c1 InChI=1S/C21H24O4/c1-6-7-14-10-16-13(2)20(25-21(16)19(11-14)24-5)15-8-9-17(22-3)18(12-15)23-4/h6-13,20H,1-5H3/b7-6+/t13-,20-/m1/s1 ITFKWUHXYCXXFF-XSOBDOKWSA-N 50303154 (+)-Acuminatin::CHEMBL571195::acuminatin Prostaglandin G/H synthase 2 Ovis aries 28700 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303154&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6441048 104157515 CHEMBL571195 ZINC05132927 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905776 COc1ccc(cc1OC)[C@@H]1OC2=CC(=O)C(CC=C)=C[C@@]2(OC)[C@@H]1C InChI=1S/C21H24O5/c1-6-7-15-12-21(25-5)13(2)20(26-19(21)11-16(15)22)14-8-9-17(23-3)18(10-14)24-4/h6,8-13,20H,1,7H2,2-5H3/t13-,20-,21-/m1/s1 VDYACOATPFOZIO-OBVPDXSSSA-N 50303155 (+)-Denudatin B::CHEMBL571196 Prostaglandin G/H synthase 2 Ovis aries 446000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303155&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 40617444 104157516 CHEMBL571196 ZINC06468453 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905777 COc1ccc(cc1OC)[C@H]1OC2=CC(=O)C(CC=C)=C[C@]2(OC)[C@@H]1C InChI=1S/C21H24O5/c1-6-7-15-12-21(25-5)13(2)20(26-19(21)11-16(15)22)14-8-9-17(23-3)18(10-14)24-4/h6,8-13,20H,1,7H2,2-5H3/t13-,20+,21+/m1/s1 VDYACOATPFOZIO-UBWHGVKJSA-N 50001747 (+)-Kadsurenone::(Kadsurenone)5-Allyl-2-(3,4-dimethoxy-phenyl)-3a-methoxy-3-methyl-3,3a-dihydro-2H-benzofuran-6-one::5-Allyl-2-(3,4-dimethoxy-phenyl)-3a-methoxy-3-methyl-3,3a-dihydro-2H-benzofuran-6-one::CHEMBL296958::KADSURENONE Prostaglandin G/H synthase 2 Ovis aries 246000 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001747&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122159 103916141 CHEMBL296958 C10638 ZINC04098814 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905778 C[C@@H]1[C@H](Oc2cc(O)c(CC=C)cc12)c1ccc2OCOc2c1 InChI=1S/C19H18O4/c1-3-4-12-7-14-11(2)19(23-17(14)9-15(12)20)13-5-6-16-18(8-13)22-10-21-16/h3,5-9,11,19-20H,1,4,10H2,2H3/t11-,19-/m0/s1 ZEACHMAUZGHOTQ-WLRWDXFRSA-N 50303156 CHEMBL578402::Liliflol A Prostaglandin G/H synthase 2 Ovis aries 98700 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303156&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 45487097 104157517 CHEMBL578402 ZINC45299099 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905779 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 113 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50905780 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2530 ChEMBL 10.1016/j.bmcl.2009.10.069 10.7270/Q2J1043X 19880317 Coy, ED; Cuca, LE; Sefkow, M Universidad Nacional de Colombia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931586 Oc1ccccc1\C=C(\C(=O)c1ccc(Cl)cc1)C(=O)C(F)(F)F InChI=1S/C17H10ClF3O3/c18-12-7-5-10(6-8-12)15(23)13(16(24)17(19,20)21)9-11-3-1-2-4-14(11)22/h1-9,22H/b13-9- LXLKZFQUMRLIRI-LCYFTJDESA-N 50382198 CHEMBL2021951 Prostaglandin G/H synthase 2 Ovis aries 46000 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382198&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70694044 160861281 CHEMBL2021951 ZINC84618614 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931587 Oc1ccc(\C=C(\C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1 InChI=1S/C17H10ClF3O3/c18-12-5-3-11(4-6-12)15(23)14(16(24)17(19,20)21)9-10-1-7-13(22)8-2-10/h1-9,22H/b14-9- FSFVVJZMYYWZHX-ZROIWOOFSA-N 50382196 CHEMBL2024214 Prostaglandin G/H synthase 2 Ovis aries 1200 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382196&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70692007 160861279 CHEMBL2024214 ZINC84618616 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931588 COc1ccc(\C=C(\C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1 InChI=1S/C18H12ClF3O3/c1-25-14-8-2-11(3-9-14)10-15(17(24)18(20,21)22)16(23)12-4-6-13(19)7-5-12/h2-10H,1H3/b15-10- DOIFCHKIVPLCDT-GDNBJRDFSA-N 50382199 CHEMBL2024215 Prostaglandin G/H synthase 2 Ovis aries 3300 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382199&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70681441 160861282 CHEMBL2024215 ZINC84618623 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931589 COc1ccc(\C=C(\C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1OC InChI=1S/C19H14ClF3O4/c1-26-15-8-3-11(10-16(15)27-2)9-14(18(25)19(21,22)23)17(24)12-4-6-13(20)7-5-12/h3-10H,1-2H3/b14-9- XUTFFBUIEICGLR-ZROIWOOFSA-N 50382200 CHEMBL2024216 Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382200&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70694045 160861283 CHEMBL2024216 ZINC84618625 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931590 [O-][N+](=O)c1cccc(\C=C(\C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)c1 InChI=1S/C17H9ClF3NO4/c18-12-6-4-11(5-7-12)15(23)14(16(24)17(19,20)21)9-10-2-1-3-13(8-10)22(25)26/h1-9H/b14-9- LRHDXZKXRBZPNR-ZROIWOOFSA-N 50382201 CHEMBL2024217 Prostaglandin G/H synthase 2 Ovis aries 660 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382201&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70692008 160861284 CHEMBL2024217 ZINC84618628 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931591 FC(F)(F)C(=O)C(=C/c1ccco1)\C(=O)c1ccc(Cl)cc1 InChI=1S/C15H8ClF3O3/c16-10-5-3-9(4-6-10)13(20)12(14(21)15(17,18)19)8-11-2-1-7-22-11/h1-8H/b12-8- QWFHPNNHULOHCL-WQLSENKSSA-N 50382202 CHEMBL2024218 Prostaglandin G/H synthase 2 Ovis aries 40200 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382202&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70689855 160861285 CHEMBL2024218 ZINC84618630 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931592 Oc1ccccc1\C=C1/C(=NN=C1C(F)(F)F)c1ccc(Cl)cc1 InChI=1S/C17H10ClF3N2O/c18-12-7-5-10(6-8-12)15-13(16(23-22-15)17(19,20)21)9-11-3-1-2-4-14(11)24/h1-9,24H/b13-9+ KRBNVUDQZNNBOL-UKTHLTGXSA-N 50382203 CHEMBL2024219 Prostaglandin G/H synthase 2 Ovis aries 44400 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382203&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70696171 160861286 CHEMBL2024219 ZINC84616536 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931593 COc1ccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)cc1 InChI=1S/C18H12ClF3N2O/c1-25-14-8-2-11(3-9-14)10-15-16(12-4-6-13(19)7-5-12)23-24-17(15)18(20,21)22/h2-10H,1H3/b15-10+ KZNLGDUIZXDGQF-XNTDXEJSSA-N 50382205 CHEMBL2024221 Prostaglandin G/H synthase 2 Ovis aries 2100 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382205&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70685664 160861288 CHEMBL2024221 ZINC84616539 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931594 COc1ccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)cc1OC InChI=1S/C19H14ClF3N2O2/c1-26-15-8-3-11(10-16(15)27-2)9-14-17(12-4-6-13(20)7-5-12)24-25-18(14)19(21,22)23/h3-10H,1-2H3/b14-9+ LGQHDQJKEAWBIH-NTEUORMPSA-N 50382206 CHEMBL2024222 Prostaglandin G/H synthase 2 Ovis aries 290 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382206&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70685665 160861289 CHEMBL2024222 ZINC84616542 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931595 [O-][N+](=O)c1cccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)c1 InChI=1S/C17H9ClF3N3O2/c18-12-6-4-11(5-7-12)15-14(16(23-22-15)17(19,20)21)9-10-2-1-3-13(8-10)24(25)26/h1-9H/b14-9+ GVXODOYJNPGYIR-NTEUORMPSA-N 50382207 CHEMBL2024223 Prostaglandin G/H synthase 2 Ovis aries 430 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382207&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70696172 160861290 CHEMBL2024223 ZINC84616544 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931596 FC(F)(F)C1=NN=C(\C1=C/c1ccco1)c1ccc(Cl)cc1 InChI=1S/C15H8ClF3N2O/c16-10-5-3-9(4-6-10)13-12(8-11-2-1-7-22-11)14(21-20-13)15(17,18)19/h1-8H/b12-8+ VXIIXHJENNKTRA-XYOKQWHBSA-N 50382197 CHEMBL2024224 Prostaglandin G/H synthase 2 Ovis aries 48000 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382197&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70694046 160861280 CHEMBL2024224 ZINC84602591 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931597 FC(F)(F)c1[nH]nc(c1Cc1ccccc1)-c1ccc(Cl)cc1 InChI=1S/C17H12ClF3N2/c18-13-8-6-12(7-9-13)15-14(10-11-4-2-1-3-5-11)16(23-22-15)17(19,20)21/h1-9H,10H2,(H,22,23) BVIZPUHJNAGZAS-UHFFFAOYSA-N 50382208 CHEMBL2024225 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382208&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70685666 160861291 CHEMBL2024225 ZINC84602866 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931598 FC(F)(F)c1nn(c(c1\C=N\c1ccc(Br)cc1)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C23H14BrClF3N3/c24-16-8-12-18(13-9-16)29-14-20-21(15-6-10-17(25)11-7-15)31(19-4-2-1-3-5-19)30-22(20)23(26,27)28/h1-14H/b29-14+ NMRMYYXVNUPSSC-IPPBACCNSA-N 50382209 CHEMBL2024226 Prostaglandin G/H synthase 2 Ovis aries 3200 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382209&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70683559 160861292 CHEMBL2024226 ZINC84602867 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931599 FC(F)(F)c1nn(c(c1\C=N\c1ccccc1Cl)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C23H14Cl2F3N3/c24-16-12-10-15(11-13-16)21-18(14-29-20-9-5-4-8-19(20)25)22(23(26,27)28)30-31(21)17-6-2-1-3-7-17/h1-14H/b29-14+ OIIOWPYWGOKJOG-IPPBACCNSA-N 50382210 CHEMBL2024227 Prostaglandin G/H synthase 2 Ovis aries 49000 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382210&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70689857 160861293 CHEMBL2024227 ZINC84596047 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931600 [O-][N+](=O)c1ccc(cc1)\N=C\c1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F InChI=1S/C23H14ClF3N4O2/c24-16-8-6-15(7-9-16)21-20(14-28-17-10-12-19(13-11-17)31(32)33)22(23(25,26)27)29-30(21)18-4-2-1-3-5-18/h1-14H/b28-14+ SMYVRIMKKSRXII-CCVNUDIWSA-N 50382211 CHEMBL2024228 Prostaglandin G/H synthase 2 Ovis aries 410 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382211&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70696173 160861294 CHEMBL2024228 ZINC84596048 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931601 FC(F)(F)c1nn(c(c1\C=N\c1cc(cc(c1)C(F)(F)F)C(F)(F)F)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C25H13ClF9N3/c26-17-8-6-14(7-9-17)21-20(22(25(33,34)35)37-38(21)19-4-2-1-3-5-19)13-36-18-11-15(23(27,28)29)10-16(12-18)24(30,31)32/h1-13H/b36-13+ OEROYCLIMCWHCA-FIFHTESVSA-N 50382212 CHEMBL2024229 Prostaglandin G/H synthase 2 Ovis aries 260 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382212&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 60150528 160861295 CHEMBL2024229 ZINC84596053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931602 FC(F)(F)c1nn(c(c1C=C(C#N)C#N)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C20H10ClF3N4/c21-15-8-6-14(7-9-15)18-17(10-13(11-25)12-26)19(20(22,23)24)27-28(18)16-4-2-1-3-5-16/h1-10H HIZHSGYULNVIOT-UHFFFAOYSA-N 50382213 CHEMBL2024230 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382213&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70683560 160861296 CHEMBL2024230 ZINC84596055 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931603 Fc1ccc2NC(=O)C3(CC(N=N3)c3ccc(Br)cc3)c2c1 InChI=1S/C16H11BrFN3O/c17-10-3-1-9(2-4-10)14-8-16(21-20-14)12-7-11(18)5-6-13(12)19-15(16)22/h1-7,14H,8H2,(H,19,22) MPHVQQSSNCKSTG-UHFFFAOYSA-N 50382214 CHEMBL2024452 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382214&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91929829 160861297 CHEMBL2024452 ZINC84633933 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931604 Cc1ccc(cc1)C1CC2(N=N1)C(=O)Nc1ccc(F)cc21 InChI=1S/C17H14FN3O/c1-10-2-4-11(5-3-10)15-9-17(21-20-15)13-8-12(18)6-7-14(13)19-16(17)22/h2-8,15H,9H2,1H3,(H,19,22) RMRHGQDUILZSMX-UHFFFAOYSA-N 50382215 CHEMBL2024453 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382215&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91929830 160861298 CHEMBL2024453 ZINC84633937 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931605 [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)/p-1 DCOPUUMXTXDBNB-UHFFFAOYSA-M 50174201 ARTHROTEC::GP 45840::SOLARAZE::Sodium; [2-(2,6-dichloro-phenylamino)-phenyl]-acetate::US11173137, Compound Diclofenac::VOLTAREN::VOLTAREN-XR::diclofenac sodium::sodium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate Prostaglandin G/H synthase 2 Ovis aries 3100 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174201&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 3032 104060023 4509 C01690 ZINC00001281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931606 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 280 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931607 FC(F)(F)c1nn(c(c1C=C1CCCC1=O)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C22H16ClF3N2O/c23-16-11-9-14(10-12-16)20-18(13-15-5-4-8-19(15)29)21(22(24,25)26)27-28(20)17-6-2-1-3-7-17/h1-3,6-7,9-13H,4-5,8H2 RWQYQVMSGMZBAT-UHFFFAOYSA-N 50344879 2-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)cyclopentanone::CHEMBL1780077 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344879&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53248946 131347815 CHEMBL1780077 ZINC71341092 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931608 FC(F)(F)c1nn(c(c1C=O)-c1ccc(Cl)cc1)-c1ccccc1 InChI=1S/C17H10ClF3N2O/c18-12-8-6-11(7-9-12)15-14(10-24)16(17(19,20)21)22-23(15)13-4-2-1-3-5-13/h1-10H YEBAWYVHPNUTJE-UHFFFAOYSA-N 50344878 5-(4-chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde::CHEMBL1780083 Prostaglandin G/H synthase 2 Ovis aries 550 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344878&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53248948 131347814 CHEMBL1780083 ZINC71340392 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931609 Oc1ccc(\C=C2/C(=NN=C2C(F)(F)F)c2ccc(Cl)cc2)cc1 InChI=1S/C17H10ClF3N2O/c18-12-5-3-11(4-6-12)15-14(16(23-22-15)17(19,20)21)9-10-1-7-13(24)8-2-10/h1-9,24H/b14-9+ DIFPGBHWDPCWCQ-NTEUORMPSA-N 50382204 CHEMBL2024220 Prostaglandin G/H synthase 2 Ovis aries 480 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382204&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70689856 160861287 CHEMBL2024220 ZINC84616538 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50931610 CCN1CCC(=O)C(C1)=Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccccc1)C(F)(F)F InChI=1S/C24H21ClF3N3O/c1-2-30-13-12-21(32)17(15-30)14-20-22(16-8-10-18(25)11-9-16)31(19-6-4-3-5-7-19)29-23(20)24(26,27)28/h3-11,14H,2,12-13,15H2,1H3 JWMFCUROZUDFLT-UHFFFAOYSA-N 50344875 3-((5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-1-ethylpiperidin-4-one::CHEMBL1780080 Prostaglandin G/H synthase 2 Ovis aries 450 ChEMBL 10.1016/j.bmc.2012.03.044 10.7270/Q2MK6DWZ 22516672 El-Sayed, MA; Abdel-Aziz, NI; Abdel-Aziz, AA; El-Azab, AS; ElTahir, KE University of Mansoura http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344875&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53248924 131347811 CHEMBL1780080 ZINC71410724 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50937505 OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) DCOPUUMXTXDBNB-UHFFFAOYSA-N 13066 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid::CHEMBL139::Diclofenac::US11337935, Compound Diclofenac::US11478464, Compound Diclofenac::{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1021/jm201090k 10.7270/Q2W95B6H 22091869 Viegas, A; Manso, J; Corvo, MC; Marques, MM; Cabrita, EJ Faculdade de Ci�ncias e Tecnologia-UNL http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13066&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search DIF 1NR6,5U1R,3N8Y,1SV9,3CFQ,4OJ4,4XTA,2WEK,1DVX,8BSG,1PXX,5DBY,2B17,3IB0,4ZBQ,4ZBR,4Z69,4UBS,6HN0,6HN1 3033 46513484 47381 CHEMBL139 DB00586 2714 C01690 ZINC00001281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50937510 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 9000 ChEMBL 10.1021/jm201090k 10.7270/Q2W95B6H 22091869 Viegas, A; Manso, J; Corvo, MC; Marques, MM; Cabrita, EJ Faculdade de Ci�ncias e Tecnologia-UNL http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954932 C\C=C\c1ccc2O[C@H]([C@H](C)c2c1)c1ccc(O)cc1 InChI=1S/C18H18O2/c1-3-4-13-5-10-17-16(11-13)12(2)18(20-17)14-6-8-15(19)9-7-14/h3-12,18-19H,1-2H3/b4-3+/t12-,18-/m1/s1 GXJSAHXNLJFDPO-CGBXWHSCSA-N 50391886 CHEMBL2147421 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391886&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10999992 163340910 CHEMBL2147421 ZINC13407126 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954933 C\C=C\c1ccc2oc(cc2c1)-c1ccc(O)cc1 InChI=1S/C17H14O2/c1-2-3-12-4-9-16-14(10-12)11-17(19-16)13-5-7-15(18)8-6-13/h2-11,18H,1H3/b3-2+ OAMUEWCGJSSPRS-NSCUHMNNSA-N 50391887 CHEMBL2147422 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391887&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53483951 163340911 69252 CHEMBL2147422 ZINC95563210 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954934 COc1cc(O)ccc1-c1cc2cc(\C=C\C)ccc2o1 InChI=1S/C18H16O3/c1-3-4-12-5-8-16-13(9-12)10-18(21-16)15-7-6-14(19)11-17(15)20-2/h3-11,19H,1-2H3/b4-3+ LYELQAFKYBUWAN-ONEGZZNKSA-N 50391880 CHEMBL2147423 Prostaglandin G/H synthase 2 Ovis aries 7600 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391880&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 14213215 163340904 69253 CHEMBL2147423 ZINC95563939 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954937 C[C@H]1[C@@H](C)[C@H](O[C@@H]1c1ccc(O)cc1)c1ccc(O)cc1 InChI=1S/C18H20O3/c1-11-12(2)18(14-5-9-16(20)10-6-14)21-17(11)13-3-7-15(19)8-4-13/h3-12,17-20H,1-2H3/t11-,12+,17-,18-/m0/s1 PIBJADPEZQHMQS-CMKMFDCUSA-N 50391882 CHEMBL2147416 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391882&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 26389403 163340906 69246 CHEMBL2147416 ZINC15054423 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954938 COc1ccc(-c2cc3cc(\C=C\C)ccc3o2)c(O)c1 InChI=1S/C18H16O3/c1-3-4-12-5-8-17-13(9-12)10-18(21-17)15-7-6-14(20-2)11-16(15)19/h3-11,19H,1-2H3/b4-3+ VSRAHYZSNLDBKG-ONEGZZNKSA-N 50391883 CHEMBL2147424 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391883&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6440631 163340907 69254 CHEMBL2147424 ZINC05132937 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954939 C\C=C\c1ccc2oc(c(C)c2c1)-c1ccc(O)cc1 InChI=1S/C18H16O2/c1-3-4-13-5-10-17-16(11-13)12(2)18(20-17)14-6-8-15(19)9-7-14/h3-11,19H,1-2H3/b4-3+ KNFUWJAIDVAYOV-ONEGZZNKSA-N 50391884 CHEMBL463574 Prostaglandin G/H synthase 2 Ovis aries 1700 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391884&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6261723 163340908 69255 CHEMBL463574 ZINC00338268 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954947 COc1cc(O)ccc1-c1cc2cc(CCCO)ccc2o1 InChI=1S/C18H18O4/c1-21-17-11-14(20)5-6-15(17)18-10-13-9-12(3-2-8-19)4-7-16(13)22-18/h4-7,9-11,19-20H,2-3,8H2,1H3 CLYYUOMSXIPPJS-UHFFFAOYSA-N 50391881 CHEMBL2147415 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391881&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 14213209 163340905 69245 CHEMBL2147415 ZINC13339718 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954954 CS(=O)(=O)Nc1ccc(cc1OC1CCCCC1)[N+]([O-])=O InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 KTDZCOWXCWUPEO-UHFFFAOYSA-N 50029593 CHEMBL7162::N-(2-(cyclohexyloxy)-4-nitrophenyl)methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide::N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide(NS-398)::N-[2-(cyclohexyloxy)-4-nitrophenyl]methane sulfonamide::N-[2-(cyclohexyloxy)-4-nitrophenyl]methanesulfonamide::N-{2-(cyclohexyloxy)-4-[hydroxy(oxido)amino]phenyl}methanesulfonamide::NS-398::NS398 Prostaglandin G/H synthase 2 Ovis aries 2100 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029593&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NS4 3QMO 4553 103938654 73458 CHEMBL7162 ZINC03791739 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954957 C\C=C\c1ccc2O[C@@H]([C@@H](CO)c2c1)c1ccc(O)cc1 InChI=1S/C18H18O3/c1-2-3-12-4-9-17-15(10-12)16(11-19)18(21-17)13-5-7-14(20)8-6-13/h2-10,16,18-20H,11H2,1H3/b3-2+/t16-,18+/m0/s1 OGRAMAAKQPETEE-TYZWSJGGSA-N 50391888 CHEMBL2147418 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391888&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71460125 163340912 CHEMBL2147418 ZINC13461796 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954958 COc1ccc(-c2cc3cc(CCCO)ccc3o2)c(O)c1 InChI=1S/C18H18O4/c1-21-14-5-6-15(16(20)11-14)18-10-13-9-12(3-2-8-19)4-7-17(13)22-18/h4-7,9-11,19-20H,2-3,8H2,1H3 DZMMGSFVLBBPIA-UHFFFAOYSA-N 50391889 CHEMBL2147419 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391889&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 14213211 163340913 69249 CHEMBL2147419 ZINC13339721 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954960 C\C=C\c1ccc2oc(cc2c1)-c1ccc(O)cc1O InChI=1S/C17H14O3/c1-2-3-11-4-7-16-12(8-11)9-17(20-16)14-6-5-13(18)10-15(14)19/h2-10,18-19H,1H3/b3-2+ SDWZWUUOXFFJSA-NSCUHMNNSA-N 50391890 CHEMBL2147420 Prostaglandin G/H synthase 2 Ovis aries 7100 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391890&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10355545 163340914 69250 CHEMBL2147420 ZINC31159791 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50954963 C[C@H]1[C@@H](C)[C@@H](O[C@@H]1c1ccc(O)cc1)c1ccc(O)cc1 InChI=1S/C18H20O3/c1-11-12(2)18(14-5-9-16(20)10-6-14)21-17(11)13-3-7-15(19)8-4-13/h3-12,17-20H,1-2H3/t11-,12+,17-,18+ PIBJADPEZQHMQS-FRVJLOGJSA-N 50391885 CHEMBL2147417 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1021/np200343t 10.7270/Q26974ND 21800856 Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H University of Innsbruck http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391885&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 14213224 163340909 69247 CHEMBL2147417 ZINC13485957 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967988 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 20000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967989 COc1cccc2c(CC(O)=O)c(C)n(C(=O)c3ccc(Cl)cc3)c12 InChI=1S/C19H16ClNO4/c1-11-15(10-17(22)23)14-4-3-5-16(25-2)18(14)21(11)19(24)12-6-8-13(20)9-7-12/h3-9H,10H2,1-2H3,(H,22,23) IWQHEVHMLSWZRR-UHFFFAOYSA-N 50396890 CHEMBL2170686 Prostaglandin G/H synthase 2 Ovis aries >400000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396890&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 19697016 163345914 CHEMBL2170686 ZINC95554223 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967990 COc1ccc2c(CC(O)=O)c(C)n(C(=O)c3ccc(Cl)cc3)c2c1 InChI=1S/C19H16ClNO4/c1-11-16(10-18(22)23)15-8-7-14(25-2)9-17(15)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) BHDFWIHNHCVURQ-UHFFFAOYSA-N 50396891 CHEMBL2170687 Prostaglandin G/H synthase 2 Ovis aries 49000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396891&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 20361784 163345915 CHEMBL2170687 ZINC60156804 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967991 CCc1cccc2c(CC(O)=O)cn(C(=O)c3ccc(Cl)cc3)c12 InChI=1S/C19H16ClNO3/c1-2-12-4-3-5-16-14(10-17(22)23)11-21(18(12)16)19(24)13-6-8-15(20)9-7-13/h3-9,11H,2,10H2,1H3,(H,22,23) HUUDENONFAELRY-UHFFFAOYSA-N 50396892 CHEMBL2170688 Prostaglandin G/H synthase 2 Ovis aries >400000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396892&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70677689 163345916 CHEMBL2170688 ZINC95556931 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967992 Cc1cccc2c(CC(O)=O)cn(C(=O)c3ccc(Cl)cc3)c12 InChI=1S/C18H14ClNO3/c1-11-3-2-4-15-13(9-16(21)22)10-20(17(11)15)18(23)12-5-7-14(19)8-6-12/h2-8,10H,9H2,1H3,(H,21,22) ZZYDJJSXJIUDJV-UHFFFAOYSA-N 50396893 CHEMBL2170689 Prostaglandin G/H synthase 2 Ovis aries >400000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50396893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50396893&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 70677541 163345917 CHEMBL2170689 ZINC95553024 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967993 OC(=O)Cc1c(-c2ccccc2)n(C(=O)c2ccc(Cl)cc2)c2ccccc12 InChI=1S/C23H16ClNO3/c24-17-12-10-16(11-13-17)23(28)25-20-9-5-4-8-18(20)19(14-21(26)27)22(25)15-6-2-1-3-7-15/h1-13H,14H2,(H,26,27) CTOLGLQYKWARIE-UHFFFAOYSA-N 50362894 CHEMBL1946749 Prostaglandin G/H synthase 2 Ovis aries >400000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362894&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 57393522 136966956 CHEMBL1946749 ZINC73199688 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967994 CCc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(Cl)cc1 InChI=1S/C19H16ClNO3/c1-2-16-15(11-18(22)23)14-5-3-4-6-17(14)21(16)19(24)12-7-9-13(20)10-8-12/h3-10H,2,11H2,1H3,(H,22,23) PXAOCNSFMKXJLV-UHFFFAOYSA-N 50362893 CHEMBL1946565 Prostaglandin G/H synthase 2 Ovis aries >400000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362893&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53249089 136966955 CHEMBL1946565 ZINC84567131 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967995 Cc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(Cl)cc1 InChI=1S/C18H14ClNO3/c1-11-15(10-17(21)22)14-4-2-3-5-16(14)20(11)18(23)12-6-8-13(19)9-7-12/h2-9H,10H2,1H3,(H,21,22) QDAPWMKWLVMBBU-UHFFFAOYSA-N 50326129 Indometacin Prostaglandin G/H synthase 2 Ovis aries 39000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326129&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9945282 123105244 ZINC13831351 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50967996 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 20000 ChEMBL 10.1021/jm301084z 10.7270/Q2BC40NJ 22916727 Arisawa, M; Kasaya, Y; Obata, T; Sasaki, T; Nakamura, T; Araki, T; Yamamoto, K; Sasaki, A; Yamano, A; Ito, M; Abe, H; Ito, Y; Shuto, S Hokkaido University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50969246 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc1ncccc1C InChI=1S/C19H24N2O/c1-13(2)12-16-7-9-17(10-8-16)15(4)19(22)21-18-14(3)6-5-11-20-18/h5-11,13,15H,12H2,1-4H3,(H,20,21,22) ZBKGVYYUEQPQPO-UHFFFAOYSA-N 50307794 2-(4-isobutylphenyl)-N-(3-methylpyridin-2-yl)propanamide::CHEMBL596757::ibu-am5 (2) Prostaglandin G/H synthase 2 Ovis aries 20000 ChEMBL 10.1021/jm3011146 10.7270/Q2G161ZJ 23043222 Favia, AD; Habrant, D; Scarpelli, R; Migliore, M; Albani, C; Bertozzi, SM; Dionisi, M; Tarozzo, G; Piomelli, D; Cavalli, A; De Vivo, M Istituto Italiano di Tecnologia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307794&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6612586 104162155 CHEMBL596757 ZINC00753168 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50588092 Cc1cccc(C)c1N1C(=O)c2ccccc2C1=O InChI=1S/C16H13NO2/c1-10-6-5-7-11(2)14(10)17-15(18)12-8-3-4-9-13(12)16(17)19/h3-9H,1-2H3 KDCNGAZTEPFIKL-UHFFFAOYSA-N 50066441 2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione::2-(2,6-dimethylphenyl)isoindoline-1,3-dione::CHEMBL8916 Prostaglandin G/H synthase 2 Ovis aries <1 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066441&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73324 103961079 CHEMBL8916 ZINC00406630 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50588093 Cc1ccccc1N1C(=O)c2ccccc2C1=O InChI=1S/C15H11NO2/c1-10-6-2-5-9-13(10)16-14(17)11-7-3-4-8-12(11)15(16)18/h2-9H,1H3 KPYGHQALDAITMY-UHFFFAOYSA-N 50219329 CHEMBL8968 Prostaglandin G/H synthase 2 Ovis aries <1 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219329&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 94776 377007673 CHEMBL8968 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50588094 C[C@]1(CCC(=O)NC1=O)N1C(=O)c2ccc(N)cc2C1=O InChI=1S/C14H13N3O4/c1-14(5-4-10(18)16-13(14)21)17-11(19)8-3-2-7(15)6-9(8)12(17)20/h2-3,6H,4-5,15H2,1H3,(H,16,18,21)/t14-/m1/s1 RZLLVQVNEFVJBK-CQSZACIVSA-N 50111216 5-Amino-2-((R)-3-methyl-2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione::CHEMBL9197 Prostaglandin G/H synthase 2 Ovis aries <10 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111216&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10517380 104005839 CHEMBL9197 ZINC13440209 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50588131 O=C1N(C(=O)c2ccccc12)c1ccccc1 InChI=1S/C14H9NO2/c16-13-11-8-4-5-9-12(11)14(17)15(13)10-6-2-1-3-7-10/h1-9H MFUPLJQNEXUUDW-UHFFFAOYSA-N 50088679 2-Phenyl-isoindole-1,3-dione::2-phenyl-1H-isoindole-1,3(2H)-dione::2-phenylisoindoline-1,3-dione::CHEMBL9020::N-Phenylphtalimide Prostaglandin G/H synthase 2 Ovis aries <1 ChEMBL 10.1016/s0960-894x(02)00084-7 10.7270/Q28K78D9 11909713 Noguchi, T; Shimazawa, R; Nagasawa, K; Hashimoto, Y The University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088679&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 68215 103987556 CHEMBL9020 ZINC00133969 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50797703 O=C(Nc1ccccc1)N1CCc2ccccc2[C@@H]1c1ccccc1 InChI=1S/C22H20N2O/c25-22(23-19-12-5-2-6-13-19)24-16-15-17-9-7-8-14-20(17)21(24)18-10-3-1-4-11-18/h1-14,21H,15-16H2,(H,23,25)/t21-/m0/s1 ANGTYJQSMCLDLI-NRFANRHFSA-N 50254170 CHEMBL4095678 Prostaglandin G/H synthase 2 Ovis aries 470 ChEMBL 10.1016/j.bmcl.2017.06.002 10.7270/Q2NK3HG0 28610982 Guan, LP; Xia, YN; Jin, QH; Liu, BY; Wang, SH Zhejiang Ocean University Engineering Technology Research Center of Marine Biomedical Products http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254170&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 135391620 402359912 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50797704 Brc1cccc(NC(=O)N2CCc3ccccc3[C@@H]2c2ccccc2)c1 InChI=1S/C22H19BrN2O/c23-18-10-6-11-19(15-18)24-22(26)25-14-13-16-7-4-5-12-20(16)21(25)17-8-2-1-3-9-17/h1-12,15,21H,13-14H2,(H,24,26)/t21-/m0/s1 HZKHOMFILDGTQV-NRFANRHFSA-N 50254169 CHEMBL4063827 Prostaglandin G/H synthase 2 Ovis aries 1630 ChEMBL 10.1016/j.bmcl.2017.06.002 10.7270/Q2NK3HG0 28610982 Guan, LP; Xia, YN; Jin, QH; Liu, BY; Wang, SH Zhejiang Ocean University Engineering Technology Research Center of Marine Biomedical Products http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254169&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 135391666 402359911 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50797712 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 660 ChEMBL 10.1016/j.bmcl.2017.06.002 10.7270/Q2NK3HG0 28610982 Guan, LP; Xia, YN; Jin, QH; Liu, BY; Wang, SH Zhejiang Ocean University Engineering Technology Research Center of Marine Biomedical Products http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50971887 COc1ccc(cc1)-c1noc(CC(O)=O)c1-c1ccc(OC)cc1 InChI=1S/C19H17NO5/c1-23-14-7-3-12(4-8-14)18-16(11-17(21)22)25-20-19(18)13-5-9-15(24-2)10-6-13/h3-10H,11H2,1-2H3,(H,21,22) DJEIHHYCDCTAAH-UHFFFAOYSA-N 50376383 CHEMBL259972 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1016/j.ejmech.2017.06.045 10.7270/Q2D2215F 28710965 Cingolani, G; Panella, A; Perrone, MG; Vitale, P; Di Mauro, G; Fortuna, CG; Armen, RS; Ferorelli, S; Smith, WL; Scilimati, A Thomas Jefferson University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50376383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50376383&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 63X 5WBE 4237 160855473 CHEMBL259972 ZINC00003767 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 50971890 Cc1onc(-c2ccc(Cl)o2)c1-c1ccccc1 InChI=1S/C14H10ClNO2/c1-9-13(10-5-3-2-4-6-10)14(16-18-9)11-7-8-12(15)17-11/h2-8H,1H3 IPAVFMUBTIUYBW-UHFFFAOYSA-N 50153040 3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazole::CHEMBL363228 Prostaglandin G/H synthase 2 Ovis aries >50000 ChEMBL 10.1016/j.ejmech.2017.06.045 10.7270/Q2D2215F 28710965 Cingolani, G; Panella, A; Perrone, MG; Vitale, P; Di Mauro, G; Fortuna, CG; Armen, RS; Ferorelli, S; Smith, WL; Scilimati, A Thomas Jefferson University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50153040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50153040&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search P6A 5U6X 10355223 104041029 CHEMBL363228 ZINC13583263 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128571 COc1ccc2cc(ccc2c1)S(C)(=O)=O InChI=1S/C12H12O3S/c1-15-11-5-3-10-8-12(16(2,13)14)6-4-9(10)7-11/h3-8H,1-2H3 WPJQZSOSBHCSBT-UHFFFAOYSA-N 50462860 CHEMBL4241735 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462860&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 15434622 433930125 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128573 CC(C)Cc1ccc(cc1)C(C)C(O)=O InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) HEFNNWSXXWATRW-UHFFFAOYSA-N 50009859 (+-)-2-(p-isobutylphenyl)propionic acid::(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid::(+-)-ibuprofen::(+-)-p-isobutylhydratropic acid::(4-isobutylphenyl)-alpha-methylacetic acid::(RS)-ibuprofen::2-(4-isobutylphenyl)propanoic acid::2-[4-(2-methylpropyl)phenyl]propanoic acid::4-isobutylhydratropic acid::Advil::Brufen::CHEMBL521::IBUPROFEN LYSINE::Ibuprofen::Ibuprofen (1)::Motrin::alpha-(4-isobutylphenyl)propionic acid::alpha-(p-isobutylphenyl)propionic acid Prostaglandin G/H synthase 2 Ovis aries 1400 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009859&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IBP 6OCI,2WD9,1EQG,5JQB,2PWS,2BXG,3P6H,6U4X,3IB2,4RS0,4JTR,7FC4,4PH9 3672 103922841 5855 CHEMBL521 DB01050 2713 C01588 ZINC38141759 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128574 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccc(Cl)cc1 InChI=1S/C14H11ClO3S/c1-19(17,18)13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3 GLXFJTWHBIOAOX-UHFFFAOYSA-N 50462862 CHEMBL4243293 Prostaglandin G/H synthase 2 Ovis aries 11370 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462862&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11748443 433930127 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128575 COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 CMWTZPSULFXXJA-VIFPVBQESA-N 50339185 (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid::(S)-2-(6-Methoxy-naphthalen-2-yl)-propionic acid::(S)-2-(6-methoxynaphthalen-2-yl)propanoic acid::(S)-naproxen::2-(6-Methoxy-naphthalen-2-yl)-propionic acid::2-(6-Methoxy-naphthalen-2-yl)-propionic acid(naproxen)::2-(6-methoxy-2-naphthyl)propanoic acid::2-(6-methoxynaphthalen-2-yl)propanoic acid::Aleve::Anaprox::CHEMBL154::Ec-naprosyn::Equiproxen::Naprelan::Naprosyn::Naproxen::Naproxen2-(6-Methoxy-naphthalen-2-yl)-propionic acid::RS-3540::S-NAPROXEN::US11459295, Compound S-Naproxen (1)::naproxene Prostaglandin G/H synthase 2 Ovis aries 3360 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339185&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search NPS 3NT1,4PO0,4OT2,2VDB,4JQ1,3R58,5DBY,4OR0,4ZBR,4FJP 156391 125089287 7476 CHEMBL154 DB00788 5230 C01517 ZINC00105216 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128579 CC(C)Cc1ccc(cc1)S(C)(=O)=O InChI=1S/C11H16O2S/c1-9(2)8-10-4-6-11(7-5-10)14(3,12)13/h4-7,9H,8H2,1-3H3 HRHZVFKTPFMCPP-UHFFFAOYSA-N 50462864 CHEMBL4242712 Prostaglandin G/H synthase 2 Ovis aries 22040 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462864&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 23559478 433930129 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128580 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 51 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128581 CS(=O)(=O)c1ccc(cc1)C(=O)c1ccoc1 InChI=1S/C12H10O4S/c1-17(14,15)11-4-2-9(3-5-11)12(13)10-6-7-16-8-10/h2-8H,1H3 ULFFSZMVURLRPK-UHFFFAOYSA-N 50326534 CHEMBL1240537::furan-3-yl(4-(methylsulfonyl)phenyl)methanone Prostaglandin G/H synthase 2 Ovis aries 710 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326534&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 46939837 123105649 CHEMBL1240537 ZINC64490658 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128582 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(c2c1)S(C)(=O)=O InChI=1S/C18H16ClNO4S/c1-11-17(25(3,22)23)15-10-14(24-2)8-9-16(15)20(11)18(21)12-4-6-13(19)7-5-12/h4-10H,1-3H3 ZDDZDNUQSOAFAI-UHFFFAOYSA-N 50462863 CHEMBL4247064 Prostaglandin G/H synthase 2 Ovis aries 760 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462863&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145985544 433930128 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128583 CN1c2ccccc2Sc2ccc(CC(O)=O)cc12 InChI=1S/C15H13NO2S/c1-16-11-4-2-3-5-13(11)19-14-7-6-10(8-12(14)16)9-15(17)18/h2-8H,9H2,1H3,(H,17,18) LMINNBXUMGNKMM-UHFFFAOYSA-N 50462865 CHEBI:31838::Metiazinic Acid::RP-16091 Prostaglandin G/H synthase 2 Ovis aries 10450 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462865&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 4164 433930130 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128584 CN1c2ccccc2Sc2ccc(cc12)S(C)(=O)=O InChI=1S/C14H13NO2S2/c1-15-11-5-3-4-6-13(11)18-14-8-7-10(9-12(14)15)19(2,16)17/h3-9H,1-2H3 TYNAHQFPCDVDAX-UHFFFAOYSA-N 50462861 CHEMBL4248484 Prostaglandin G/H synthase 2 Ovis aries 1790 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462861&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145985095 433930126 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128585 CC(C(O)=O)c1cccc(Oc2ccccc2)c1 InChI=1S/C15H14O3/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13/h2-11H,1H3,(H,16,17) RDJGLLICXDHJDY-UHFFFAOYSA-N 54705 CHEMBL1297::Fenoprofen::UNM-0000306101::calcium;2-(3-phenoxyphenyl)propanoic acid;hydrate::calcium;2-(3-phenoxyphenyl)propionic acid;hydrate::cid_16219353 Prostaglandin G/H synthase 2 Ovis aries 26300 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54705&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search PFN 2X7H,4NED 3342 252634731 5004 CHEMBL1297 DB00573 C06997 ZINC00402909 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128586 CS(=O)(=O)c1cccc(Oc2ccccc2)c1 InChI=1S/C13H12O3S/c1-17(14,15)13-9-5-8-12(10-13)16-11-6-3-2-4-7-11/h2-10H,1H3 HPPBBUUVYFUWQJ-UHFFFAOYSA-N 50462866 CHEMBL4238821 Prostaglandin G/H synthase 2 Ovis aries 280 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462866&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 57675723 433930131 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128594 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51128595 CC(C(O)=O)c1cccc(c1)C(=O)c1ccccc1 InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) DKYWVDODHFEZIM-UHFFFAOYSA-N 50022271 2-(3-Benzoylphenyl)propionic acid::2-(3-benzoylphenyl)propanoic acid::3-Benzoyl-alpha-methylbenzeneacetic acid::3-Benzoylhydratropic acid::CHEMBL571::Dexketoprofen trometamol::KETOPROFEN::L'Acide (benzoyl-3-phenyl)-2-propionique::Orudis (TN)::m-Benzoylhydratropic acid Prostaglandin G/H synthase 2 Ovis aries 180 ChEMBL 10.1016/j.bmc.2018.06.038 10.7270/Q2S1855F 29980364 Navarro, L; Rosell, G; Sánchez, S; Boixareu, N; Pors, K; Pouplana, R; Campanera, JM; Pujol, MD Universitat de Barcelona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022271&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 9KL 6OCK,5ZWR,7JWN,6U4R 3825 103932891 6128 CHEMBL571 DB01009 4795 C01716 ZINC00005560 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51133015 CCCCC(=C(c1ccccc1)c1ccccc1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C25H26O2S/c1-3-4-15-24(20-16-18-23(19-17-20)28(2,26)27)25(21-11-7-5-8-12-21)22-13-9-6-10-14-22/h5-14,16-19H,3-4,15H2,1-2H3 QQERLQWDENETQT-UHFFFAOYSA-N 50324804 (2-(4-(methylsulfonyl)phenyl)hex-1-ene-1,1-diyl)dibenzene::CHEMBL1221731 Prostaglandin G/H synthase 2 Ovis aries 14 ChEMBL 10.1016/j.ejmech.2017.11.056 10.7270/Q21V5HMQ 29207335 Shagufta, na; Ahmad, I American University of Ras Al Khaimah http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324804&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10408088 117646125 CHEMBL1221731 ZINC38796096 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139909 COc1ccc2cc(ccc2c1)C(C)C(=O)NN1C(=O)CCC1=O InChI=1S/C18H18N2O4/c1-11(18(23)19-20-16(21)7-8-17(20)22)12-3-4-14-10-15(24-2)6-5-13(14)9-12/h3-6,9-11H,7-8H2,1-2H3,(H,19,23) VASYFZOESRJRPL-UHFFFAOYSA-N 50467258 CHEMBL4276853 Prostaglandin G/H synthase 2 Ovis aries 6990 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467258&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145983915 433934523 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139910 COc1ccc2cc(ccc2c1)C(C)c1nnc(o1)-c1ccc(O)cc1 InChI=1S/C21H18N2O3/c1-13(15-3-4-17-12-19(25-2)10-7-16(17)11-15)20-22-23-21(26-20)14-5-8-18(24)9-6-14/h3-13,24H,1-2H3 HFZLCNDKTHEBPC-UHFFFAOYSA-N 50467259 CHEMBL4280674 Prostaglandin G/H synthase 2 Ovis aries 650 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467259&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145981725 433934524 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139911 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139914 COc1ccc2cc(ccc2c1)C(C)c1nnc(SC2CCCC2)o1 InChI=1S/C20H22N2O2S/c1-13(19-21-22-20(24-19)25-18-5-3-4-6-18)14-7-8-16-12-17(23-2)10-9-15(16)11-14/h7-13,18H,3-6H2,1-2H3 BFNPSMLIEHPAQY-UHFFFAOYSA-N 50467262 CHEMBL4292225 Prostaglandin G/H synthase 2 Ovis aries 2790 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467262&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145988082 433934527 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139919 COc1ccc2cc(ccc2c1)C(C)C(=O)NN=C1CCCCCC1 InChI=1S/C21H26N2O2/c1-15(21(24)23-22-19-7-5-3-4-6-8-19)16-9-10-18-14-20(25-2)12-11-17(18)13-16/h9-15H,3-8H2,1-2H3,(H,23,24) QNNACOLQONIBRB-UHFFFAOYSA-N 50467265 CHEMBL4280289 Prostaglandin G/H synthase 2 Ovis aries 3500 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467265&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145980123 433934530 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139921 COc1ccc2cc(ccc2c1)C(C)c1nnc(SC)o1 InChI=1S/C16H16N2O2S/c1-10(15-17-18-16(20-15)21-3)11-4-5-13-9-14(19-2)7-6-12(13)8-11/h4-10H,1-3H3 HZPVSTUURYBPHC-UHFFFAOYSA-N 50467266 CHEMBL4288814 Prostaglandin G/H synthase 2 Ovis aries 2790 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467266&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145991645 433934531 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139922 COc1ccc2cc(ccc2c1)C(C)c1nnc(o1)-c1ccc(C)cc1 InChI=1S/C22H20N2O2/c1-14-4-6-16(7-5-14)22-24-23-21(26-22)15(2)17-8-9-19-13-20(25-3)11-10-18(19)12-17/h4-13,15H,1-3H3 WYIKBKIRYZNULO-UHFFFAOYSA-N 50467260 CHEMBL4288580 Prostaglandin G/H synthase 2 Ovis aries 1290 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467260&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145992751 433934525 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139931 COc1ccc2cc(ccc2c1)C(C)C(=O)NN=C1CCCCC1 InChI=1S/C20H24N2O2/c1-14(20(23)22-21-18-6-4-3-5-7-18)15-8-9-17-13-19(24-2)11-10-16(17)12-15/h8-14H,3-7H2,1-2H3,(H,22,23) SALISVVUWBLVQU-UHFFFAOYSA-N 50467261 CHEMBL4277073 Prostaglandin G/H synthase 2 Ovis aries 1200 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467261&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145982711 433934526 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139932 COc1ccc2cc(ccc2c1)C(C)C(=O)NN1C(=O)C=CC1=O InChI=1S/C18H16N2O4/c1-11(18(23)19-20-16(21)7-8-17(20)22)12-3-4-14-10-15(24-2)6-5-13(14)9-12/h3-11H,1-2H3,(H,19,23) ANQREWKDRHPVLP-UHFFFAOYSA-N 50467267 CHEMBL4287499 Prostaglandin G/H synthase 2 Ovis aries 5700 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467267&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145990924 433934532 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139933 COc1ccc2cc(ccc2c1)C(C)C(=O)NN1C(=O)c2ccccc2C1=O InChI=1S/C22H18N2O4/c1-13(14-7-8-16-12-17(28-2)10-9-15(16)11-14)20(25)23-24-21(26)18-5-3-4-6-19(18)22(24)27/h3-13H,1-2H3,(H,23,25) LJXMYXRQNQFLRF-UHFFFAOYSA-N 50467268 CHEMBL4292002 Prostaglandin G/H synthase 2 Ovis aries 6990 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467268&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 49787660 433934533 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139934 COc1ccc2cc(ccc2c1)C(C)c1nnc(o1)-c1ccc(cc1)[N+]([O-])=O InChI=1S/C21H17N3O4/c1-13(15-3-4-17-12-19(27-2)10-7-16(17)11-15)20-22-23-21(28-20)14-5-8-18(9-6-14)24(25)26/h3-13H,1-2H3 GZKDLJLTNJCZQV-UHFFFAOYSA-N 50467264 CHEMBL4284126 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467264&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145992789 433934529 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139935 COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1N InChI=1S/C15H16N4OS/c1-9(14-17-18-15(21)19(14)16)10-3-4-12-8-13(20-2)6-5-11(12)7-10/h3-9H,16H2,1-2H3,(H,18,21) PEENUFMKGXFWCW-UHFFFAOYSA-N 50467269 CHEMBL3754769 Prostaglandin G/H synthase 2 Ovis aries 2500 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467269&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10518322 433934534 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139936 COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1\N=C\c1ccccc1 InChI=1S/C22H20N4OS/c1-15(17-8-9-19-13-20(27-2)11-10-18(19)12-17)21-24-25-22(28)26(21)23-14-16-6-4-3-5-7-16/h3-15H,1-2H3,(H,25,28)/b23-14+ IMLTVIQBQHAEMA-OEAKJJBVSA-N 50467270 CHEMBL4286289 Prostaglandin G/H synthase 2 Ovis aries 890 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467270&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145990224 433934535 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139937 COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1\N=C\c1cccc(Br)c1 InChI=1S/C22H19BrN4OS/c1-14(16-6-7-18-12-20(28-2)9-8-17(18)11-16)21-25-26-22(29)27(21)24-13-15-4-3-5-19(23)10-15/h3-14H,1-2H3,(H,26,29)/b24-13+ SBKOJJJDLUQJCV-ZMOGYAJESA-N 50467271 CHEMBL4293512 Prostaglandin G/H synthase 2 Ovis aries 800 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467271&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145987910 433934536 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51139938 COc1ccc2cc(ccc2c1)C(C)c1n[nH]c(=S)n1\N=C\c1ccc(O)cc1 InChI=1S/C22H20N4O2S/c1-14(16-5-6-18-12-20(28-2)10-7-17(18)11-16)21-24-25-22(29)26(21)23-13-15-3-8-19(27)9-4-15/h3-14,27H,1-2H3,(H,25,29)/b23-13+ DVLQVUDXBQKALS-YDZHTSKRSA-N 50467263 CHEMBL4282907 Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.1016/j.ejmech.2018.09.007 10.7270/Q2RF5XQD 30216848 El-Husseiny, WM; El-Sayed, MA; Abdel-Aziz, NI; El-Azab, AS; Asiri, YA; Abdel-Aziz, AA Mansoura University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50467263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50467263&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145979101 433934528 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169998 Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1 InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H KZNIFHPLKGYRTM-UHFFFAOYSA-N 7458 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one::5,7-dihydroxy-2-(4-hydroxyphenyl)-chromen-4-one::Apigenin::Apigenin (2)::Apigenin (3)::Apigenin (7)::Apigenin, 13::CHEMBL28::Naringenin, 18::US10278929, Apigenin::US11337935, Compound Apigenin::acs.jmedchem.1c00409_ST.789::cid_5280443::jm5b01461, Compound 90 Prostaglandin G/H synthase 2 Ovis aries >370000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7458&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AGI 4HKK,4DGM,5I2H,5AUV,4DER,7D3A,3AMY,4WO0,3CF9,5UQT 5280443 11108249 18388 CHEMBL28 DB07352 4136 C01477 ZINC03871576 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169999 COc1cc(O)cc(CCc2cccc(O)c2)c1 InChI=1S/C15H16O3/c1-18-15-9-12(8-14(17)10-15)6-5-11-3-2-4-13(16)7-11/h2-4,7-10,16-17H,5-6H2,1H3 VYQXIUVIYICVCM-UHFFFAOYSA-N 246487 Batatasin III (4) Prostaglandin G/H synthase 2 Ovis aries >409000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246487&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10466989 341104274 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51170001 COc1cc(O)cc2CCc3ccccc3Oc12 InChI=1S/C15H14O3/c1-17-14-9-12(16)8-11-7-6-10-4-2-3-5-13(10)18-15(11)14/h2-5,8-9,16H,6-7H2,1H3 OZBWMOVXDLPRHR-UHFFFAOYSA-N 50479916 CHEMBL474975 Prostaglandin G/H synthase 2 Ovis aries >412000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50479916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50479916&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44572329 433947181 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51170003 Oc1ccc(\C=C\C=C\C(=O)\C=C\c2ccc(O)cc2)cc1 InChI=1S/C19H16O3/c20-17(10-7-16-8-13-19(22)14-9-16)4-2-1-3-15-5-11-18(21)12-6-15/h1-14,21-22H/b3-1+,4-2+,10-7+ PALMCMYYFAHUGA-BPTNNVFMSA-N 246499 (1E,4E,6E)-1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one (19) Prostaglandin G/H synthase 2 Ovis aries 10900 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246499&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10447050 341104286 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51170005 COc1ccc(CCc2ccccc2O)cc1OC InChI=1S/C16H18O3/c1-18-15-10-8-12(11-16(15)19-2)7-9-13-5-3-4-6-14(13)17/h3-6,8,10-11,17H,7,9H2,1-2H3 RIRTUCMKBRKEEJ-UHFFFAOYSA-N 50479919 2-(3,4-Dimethoxyphenethyl)Phenol::CHEMBL472762 Prostaglandin G/H synthase 2 Ovis aries >387000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50479919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50479919&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 19423878 433947184 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51170006 COc1c(O)cc(CCc2ccccc2)cc1O InChI=1S/C15H16O3/c1-18-15-13(16)9-12(10-14(15)17)8-7-11-5-3-2-4-6-11/h2-6,9-10,16-17H,7-8H2,1H3 UXZPELIPQAUZMK-UHFFFAOYSA-N 246488 2',4-Dihydroxy-3,5-dihydroxy-4-methoxybibenzyl (6) Prostaglandin G/H synthase 2 Ovis aries >409000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246488&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44572212 341104275 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183422 CS(=O)(=O)c1ccc(cc1)-c1nc2CCCCc2n1-c1ccc(F)cc1 InChI=1S/C20H19FN2O2S/c1-26(24,25)17-12-6-14(7-13-17)20-22-18-4-2-3-5-19(18)23(20)16-10-8-15(21)9-11-16/h6-13H,2-5H2,1H3 ZBNGNOLIDKZAJR-UHFFFAOYSA-N 50486702 CHEMBL2234963 Prostaglandin G/H synthase 2 Ovis aries 340 ChEMBL 10.1007/s00044-011-9709-y 10.7270/Q21J9DNB n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486702&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 66561080 433953967 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183423 CS(=O)(=O)c1ccc(cc1)-c1nc2CCCCc2n1-c1ccc(Cl)cc1 InChI=1S/C20H19ClN2O2S/c1-26(24,25)17-12-6-14(7-13-17)20-22-18-4-2-3-5-19(18)23(20)16-10-8-15(21)9-11-16/h6-13H,2-5H2,1H3 FATSHCYJTBOXKX-UHFFFAOYSA-N 50486703 CHEMBL2234964 Prostaglandin G/H synthase 2 Ovis aries 670 ChEMBL 10.1007/s00044-011-9709-y 10.7270/Q21J9DNB n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486703&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76333333 433953968 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183428 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1007/s00044-011-9709-y 10.7270/Q21J9DNB n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183429 Cc1ccc(cc1)-n1c2CCCCc2nc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H22N2O2S/c1-15-7-11-17(12-8-15)23-20-6-4-3-5-19(20)22-21(23)16-9-13-18(14-10-16)26(2,24)25/h7-14H,3-6H2,1-2H3 LJZJTKSTSCITFW-UHFFFAOYSA-N 50486704 CHEMBL2234965 Prostaglandin G/H synthase 2 Ovis aries 620 ChEMBL 10.1007/s00044-011-9709-y 10.7270/Q21J9DNB n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486704&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76315158 433953969 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183431 CC(=O)Nc1ccc(cc1)-n1c2CCCCc2nc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C22H23N3O3S/c1-15(26)23-17-9-11-18(12-10-17)25-21-6-4-3-5-20(21)24-22(25)16-7-13-19(14-8-16)29(2,27)28/h7-14H,3-6H2,1-2H3,(H,23,26) UFLPQYIOKNNSLX-UHFFFAOYSA-N 50486707 CHEMBL2234967 Prostaglandin G/H synthase 2 Ovis aries 690 ChEMBL 10.1007/s00044-011-9709-y 10.7270/Q21J9DNB n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486707&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76318804 433953972 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183432 CS(=O)(=O)c1ccc(cc1)-c1nc2CCCCc2n1-c1ccccc1 InChI=1S/C20H20N2O2S/c1-25(23,24)17-13-11-15(12-14-17)20-21-18-9-5-6-10-19(18)22(20)16-7-3-2-4-8-16/h2-4,7-8,11-14H,5-6,9-10H2,1H3 IFOINKMDDYWPES-UHFFFAOYSA-N 50486706 CHEMBL2234962 Prostaglandin G/H synthase 2 Ovis aries 550 ChEMBL 10.1007/s00044-011-9709-y 10.7270/Q21J9DNB n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486706&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76311589 433953971 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183433 COc1ccc(cc1)-n1c2CCCCc2nc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H22N2O3S/c1-26-17-11-9-16(10-12-17)23-20-6-4-3-5-19(20)22-21(23)15-7-13-18(14-8-15)27(2,24)25/h7-14H,3-6H2,1-2H3 ABLUKBSGCHZFDL-UHFFFAOYSA-N 50486705 CHEMBL2234966 Prostaglandin G/H synthase 2 Ovis aries 370 ChEMBL 10.1007/s00044-011-9709-y 10.7270/Q21J9DNB n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486705&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76307995 433953970 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183436 Cc1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C23H20N2O2S/c1-16-8-10-19(11-9-16)23-24-21(17-6-4-3-5-7-17)22(25-23)18-12-14-20(15-13-18)28(2,26)27/h3-15H,1-2H3,(H,24,25) RDKAJDWVGICSPW-UHFFFAOYSA-N 50486708 CHEMBL2234972 Prostaglandin G/H synthase 2 Ovis aries 240 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486708&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76322469 433953973 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183437 CS(=O)(=O)c1ccc(cc1)-c1nc([nH]c1-c1ccccc1)-c1ccc(Cl)cc1 InChI=1S/C22H17ClN2O2S/c1-28(26,27)19-13-9-16(10-14-19)21-20(15-5-3-2-4-6-15)24-22(25-21)17-7-11-18(23)12-8-17/h2-14H,1H3,(H,24,25) YFKXWONBIRMKRC-UHFFFAOYSA-N 50486709 CHEMBL2234971 Prostaglandin G/H synthase 2 Ovis aries 350 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486709&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76333335 433953974 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183439 CS(=O)(=O)c1ccc(cc1)-c1nc([nH]c1-c1ccccc1)-c1ccc(F)cc1 InChI=1S/C22H17FN2O2S/c1-28(26,27)19-13-9-16(10-14-19)21-20(15-5-3-2-4-6-15)24-22(25-21)17-7-11-18(23)12-8-17/h2-14H,1H3,(H,24,25) YNOHGDVJTWYICE-UHFFFAOYSA-N 50486711 CHEMBL2234973 Prostaglandin G/H synthase 2 Ovis aries 160 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486711&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76318806 433953976 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183440 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183441 CS(=O)(=O)c1ccc(cc1)-c1nc([nH]c1-c1ccccc1)-c1ccccc1 InChI=1S/C22H18N2O2S/c1-27(25,26)19-14-12-17(13-15-19)21-20(16-8-4-2-5-9-16)23-22(24-21)18-10-6-3-7-11-18/h2-15H,1H3,(H,23,24) VTDFZODTERQBTH-UHFFFAOYSA-N 50486712 CHEMBL2234974 Prostaglandin G/H synthase 2 Ovis aries 230 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486712&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76311590 433953977 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183446 COc1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C23H20N2O3S/c1-28-19-12-8-18(9-13-19)23-24-21(16-6-4-3-5-7-16)22(25-23)17-10-14-20(15-11-17)29(2,26)27/h3-15H,1-2H3,(H,24,25) QAEACDAIKHMHKE-UHFFFAOYSA-N 50486714 CHEMBL2234970 Prostaglandin G/H synthase 2 Ovis aries 200 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486714&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76318805 433953979 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183449 CC(=O)Nc1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccc(cc1)S(C)(=O)=O InChI=1S/C24H21N3O3S/c1-16(28)25-20-12-8-19(9-13-20)24-26-22(17-6-4-3-5-7-17)23(27-24)18-10-14-21(15-11-18)31(2,29)30/h3-15H,1-2H3,(H,25,28)(H,26,27) OCTWYSMPGBBJET-UHFFFAOYSA-N 50486710 CHEMBL2234968 Prostaglandin G/H synthase 2 Ovis aries 310 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486710&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76333334 433953975 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51183451 CS(=O)(=O)c1ccc(cc1)-c1nc([nH]c1-c1ccccc1)-c1ccc(O)cc1 InChI=1S/C22H18N2O3S/c1-28(26,27)19-13-9-16(10-14-19)21-20(15-5-3-2-4-6-15)23-22(24-21)17-7-11-18(25)12-8-17/h2-14,25H,1H3,(H,23,24) VNXZPOBIDSDMPU-UHFFFAOYSA-N 50486713 CHEMBL2234969 Prostaglandin G/H synthase 2 Ovis aries 150 ChEMBL 10.1007/s00044-011-9710-5 10.7270/Q2WS8X35 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50486713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50486713&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 136228192 433953978 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169970 O[C@H](CCc1ccc(O)cc1)C[C@H](O)CCc1ccc(O)cc1 InChI=1S/C19H24O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-4,7-10,18-23H,5-6,11-13H2/t18-,19-/m1/s1 GZVIQGVWSNEONZ-RTBURBONSA-N 246502 (3R,5R)-3,5-dihydroxy-1,7-bis(4-hydroxyphenyl)-3,5-heptanediol (22) Prostaglandin G/H synthase 2 Ovis aries >316000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246502&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11034432 341104289 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169971 COc1cc(O)cc(CCc2ccccc2O)c1 InChI=1S/C15H16O3/c1-18-14-9-11(8-13(16)10-14)6-7-12-4-2-3-5-15(12)17/h2-5,8-10,16-17H,6-7H2,1H3 IUMFLNFLJUUODE-UHFFFAOYSA-N 50211956 2-(3-hydroxy-5-methoxyphenethyl)phenol::Batatasin IV (5)::CHEMBL228126::batatasin IV Prostaglandin G/H synthase 2 Ovis aries >409000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50211956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50211956&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 8KW 5N3W 181271 104088027 CHEMBL228126 C10247 ZINC04098623 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169972 COc1cc(CC[C@@H](O)C[C@H](O)CCc2ccc(O)c(OC)c2)ccc1O InChI=1S/C21H28O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,16-17,22-25H,3-4,7-8,13H2,1-2H3/t16-,17-/m1/s1 OELMAFBLFOKZJD-IAGOWNOFSA-N 246503 (3R,5R)-1,7-bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanediol Prostaglandin G/H synthase 2 Ovis aries >265000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246503&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10883331 341104290 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169973 COc1cc(O)cc2CCc3cccc(O)c3-c12 InChI=1S/C15H14O3/c1-18-13-8-11(16)7-10-6-5-9-3-2-4-12(17)14(9)15(10)13/h2-4,7-8,16-17H,5-6H2,1H3 UZIPEBBTICXJHN-UHFFFAOYSA-N 246495 Hircinol (13) Prostaglandin G/H synthase 2 Ovis aries >412000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246495&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 442705 341104282 C10261 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169974 COc1cc(CCc2ccccc2O)cc(OC)c1O InChI=1S/C16H18O4/c1-19-14-9-11(10-15(20-2)16(14)18)7-8-12-5-3-4-6-13(12)17/h3-6,9-10,17-18H,7-8H2,1-2H3 JCRLULKCRHDSOL-UHFFFAOYSA-N 50479917 CHEMBL475651 Prostaglandin G/H synthase 2 Ovis aries >364000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50479917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50479917&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 14731336 433947182 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169975 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 558 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169977 COc1cc2c(ccc3cc(O)cc(OC)c23)cc1O InChI=1S/C16H14O4/c1-19-14-8-12-9(6-13(14)18)3-4-10-5-11(17)7-15(20-2)16(10)12/h3-8,17-18H,1-2H3 YKFWCNBTQYCJQV-UHFFFAOYSA-N 246493 3,5-Dimethoxy-2,7-phenanthrenediol (11) Prostaglandin G/H synthase 2 Ovis aries 9980 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246493&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44572330 341104280 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169979 COc1cc(CCc2cc(O)cc(O)c2)ccc1O InChI=1S/C15H16O4/c1-19-15-8-10(4-5-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h4-9,16-18H,2-3H2,1H3 KPFFMALTIRFAHW-UHFFFAOYSA-N 246485 Tristin (1) Prostaglandin G/H synthase 2 Ovis aries 18000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246485&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 15736297 341104272 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169980 Oc1ccc(CCC(=O)\C=C\C=C\c2ccc(O)cc2)cc1 InChI=1S/C19H18O3/c20-17(10-7-16-8-13-19(22)14-9-16)4-2-1-3-15-5-11-18(21)12-6-15/h1-6,8-9,11-14,21-22H,7,10H2/b3-1+,4-2+ QIROPQQWKBMABC-ZPUQHVIOSA-N 246500 (4E,6E)-1,7-bis(4-hydroxyphenyl)-4,6-heptadien-3-one (20) Prostaglandin G/H synthase 2 Ovis aries 16600 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246500&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10613719 341104287 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169982 COc1cc(O)c-2c(CCc3cc(O)ccc-23)c1 InChI=1S/C15H14O3/c1-18-12-7-10-3-2-9-6-11(16)4-5-13(9)15(10)14(17)8-12/h4-8,16-17H,2-3H2,1H3 RDKDIPDDUFMMMT-UHFFFAOYSA-N 246496 2,5-Dihydroxy-7-methoxy-9,10-dihydrophenanthrene (14) Prostaglandin G/H synthase 2 Ovis aries 45400 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246496&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 442702 341104283 C10257 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169983 Oc1cc(O)cc(CCc2ccccc2O)c1 InChI=1S/C14H14O3/c15-12-7-10(8-13(16)9-12)5-6-11-3-1-2-4-14(11)17/h1-4,7-9,15-17H,5-6H2 QNLYZTMYRVYPMN-UHFFFAOYSA-N 64584 2',3,5-Trihydroxybibenzyl (2) Prostaglandin G/H synthase 2 Ovis aries 86800 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64584&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 442699 341103325 C10253 ZINC06519558 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169991 Oc1cc(O)c2Oc3ccccc3CCc2c1 InChI=1S/C14H12O3/c15-11-7-10-6-5-9-3-1-2-4-13(9)17-14(10)12(16)8-11/h1-4,7-8,15-16H,5-6H2 CYFMLBQMCKMNJT-UHFFFAOYSA-N 50479918 CHEMBL474974 Prostaglandin G/H synthase 2 Ovis aries 28000 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50479918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50479918&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44572328 433947183 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169993 COc1c(O)cccc1CCc1cc(O)cc(O)c1 InChI=1S/C15H16O4/c1-19-15-11(3-2-4-14(15)18)6-5-10-7-12(16)9-13(17)8-10/h2-4,7-9,16-18H,5-6H2,1H3 FNNQAZPVTHKZOI-UHFFFAOYSA-N 246486 3,3',5-Trihydroxy-2'-methoxybibenzyl (3) Prostaglandin G/H synthase 2 Ovis aries 6910 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246486&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 44156958 341104273 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51169995 COc1cc(\C=C\C=C\C(=O)CCc2ccc(O)cc2)ccc1O InChI=1S/C20H20O4/c1-24-20-14-16(9-13-19(20)23)4-2-3-5-17(21)10-6-15-7-11-18(22)12-8-15/h2-5,7-9,11-14,22-23H,6,10H2,1H3/b4-2+,5-3+ VJBQUBGTUNBGDY-ZUVMSYQZSA-N 246501 (4E,6E)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-4,6-heptadien-3-one (21) Prostaglandin G/H synthase 2 Ovis aries 23700 ChEMBL 10.1016/j.bmc.2009.02.057 10.7270/Q2RF5XTR 19303782 Yang, MH; Yoon, KD; Chin, YW; Park, JH; Kim, J Seoul National University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=246501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=246501&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 24901215 341104288 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192941 Cc1ccc2C(=O)N(Cc3ccc(cc3)S(N)(=O)=O)C(=O)c2c1 InChI=1S/C16H14N2O4S/c1-10-2-7-13-14(8-10)16(20)18(15(13)19)9-11-3-5-12(6-4-11)23(17,21)22/h2-8H,9H2,1H3,(H2,17,21,22) OIRLQQUZMRVLNZ-UHFFFAOYSA-N 50035681 CHEMBL2377787 Prostaglandin G/H synthase 2 Ovis aries 50000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035681&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602412 313066677 CHEMBL2377787 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192944 OC(=O)c1ccc(cc1)N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O InChI=1S/C15H8N2O6/c18-13-11-6-5-10(17(22)23)7-12(11)14(19)16(13)9-3-1-8(2-4-9)15(20)21/h1-7H,(H,20,21) MRRDXZGCMXRGFR-UHFFFAOYSA-N 50035678 CHEMBL2377774 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035678&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 746816 313066675 CHEMBL2377774 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192945 NS(=O)(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O InChI=1S/C30H24N4S/c35-30(33-21-8-2-1-3-9-21)34-22-16-14-20(15-17-22)29(25-18-31-27-12-6-4-10-23(25)27)26-19-32-28-13-7-5-11-24(26)28/h1-19,29,31-32H,(H2,33,34,35) YSJYDNVXXPFJIF-UHFFFAOYSA-N 152638 4-(1,3-Dioxoisoindolin-2-yl)benzenesulphonamide (1)::BDBM50222606 Prostaglandin G/H synthase 2 Ovis aries 25000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=152638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=152638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 91937818 252826889 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192946 NS(=O)(=O)c1ccc(cc1)N1C(=O)c2cccc3cccc(C1=O)c23 InChI=1S/C18H12N2O4S/c19-25(23,24)13-9-7-12(8-10-13)20-17(21)14-5-1-3-11-4-2-6-15(16(11)14)18(20)22/h1-10H,(H2,19,23,24) MZZZNXUNTMXPRZ-UHFFFAOYSA-N 50035698 CHEMBL2377779 Prostaglandin G/H synthase 2 Ovis aries 4000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035698&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 1124687 313066693 CHEMBL2377779 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192949 NS(=O)(=O)c1ccc(cc1)N1C(=O)c2cc(Cl)c(Cl)cc2C1=O InChI=1S/C14H8Cl2N2O4S/c15-11-5-9-10(6-12(11)16)14(20)18(13(9)19)7-1-3-8(4-2-7)23(17,21)22/h1-6H,(H2,17,21,22) OFKBAUDTUFJYFH-UHFFFAOYSA-N 50035671 CHEMBL2377794 Prostaglandin G/H synthase 2 Ovis aries 500 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035671&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73350410 313066668 CHEMBL2377794 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192951 OC(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O InChI=1S/C15H9NO4/c17-13-11-3-1-2-4-12(11)14(18)16(13)10-7-5-9(6-8-10)15(19)20/h1-8H,(H,19,20) HBXCMGPWVGKNRS-UHFFFAOYSA-N 45791 4-(1,3-dioxo-2-isoindolyl)benzoic acid::4-(1,3-dioxoisoindol-2-yl)benzoic acid::4-[1,3-bis(oxidanylidene)isoindol-2-yl]benzoic acid::4-phthalimidobenzoic acid::MLS-0091937.0001::cid_246499 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=45791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=45791&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 246499 252626384 ZINC00186368 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192952 NS(=O)(=O)c1ccc(cc1)N1C(=O)[C@H]2CC=CC[C@H]2C1=O InChI=1S/C14H14N2O4S/c15-21(19,20)10-7-5-9(6-8-10)16-13(17)11-3-1-2-4-12(11)14(16)18/h1-2,5-8,11-12H,3-4H2,(H2,15,19,20)/t11-,12+ YPFHKBFGEADHCD-TXEJJXNPSA-N 50035684 CHEMBL2377784 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035684&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 742873 313066680 CHEMBL2377784 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192953 NS(=O)(=O)c1ccc(CN2C(=O)CCC2=O)cc1 InChI=1S/C11H12N2O4S/c12-18(16,17)9-3-1-8(2-4-9)7-13-10(14)5-6-11(13)15/h1-4H,5-7H2,(H2,12,16,17) AYNHSSHRIRNWEB-UHFFFAOYSA-N 50035688 CHEMBL2377780 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035688&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602410 313066684 CHEMBL2377780 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192960 OC(=O)c1ccc(cc1)N1C(=O)c2cccc3cccc(C1=O)c23 InChI=1S/C19H11NO4/c21-17-14-5-1-3-11-4-2-6-15(16(11)14)18(22)20(17)13-9-7-12(8-10-13)19(23)24/h1-10H,(H,23,24) ONCKFUWLVNQAFK-UHFFFAOYSA-N 50035699 CHEMBL1501298 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035699&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 716763 313066694 CHEMBL1501298 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192961 NS(=O)(=O)c1ccc(cc1)N1C(=O)c2nccnc2C1=O InChI=1S/C12H8N4O4S/c13-21(19,20)8-3-1-7(2-4-8)16-11(17)9-10(12(16)18)15-6-5-14-9/h1-6H,(H2,13,19,20) WFYXAVWBBGFCFS-UHFFFAOYSA-N 50035680 CHEMBL2377776 Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035680&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602539 312528631 CHEMBL2377776 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192962 NS(=O)(=O)c1ccc(CN2C(=O)c3ccc(cc3C2=O)[N+]([O-])=O)cc1 InChI=1S/C15H11N3O6S/c16-25(23,24)11-4-1-9(2-5-11)8-17-14(19)12-6-3-10(18(21)22)7-13(12)15(17)20/h1-7H,8H2,(H2,16,23,24) TYCSMGJLSZYOCY-UHFFFAOYSA-N 50035676 CHEMBL2377772 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035676&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602537 313066673 CHEMBL2377772 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192963 NS(=O)(=O)c1ccc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc1 InChI=1S/C15H10Cl2N2O4S/c16-12-5-10-11(6-13(12)17)15(21)19(14(10)20)7-8-1-3-9(4-2-8)24(18,22)23/h1-6H,7H2,(H2,18,22,23) LQCOMFWTPKKPBD-UHFFFAOYSA-N 50035694 CHEMBL2377793 Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035694&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73347324 313066690 CHEMBL2377793 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192964 CC(C)(C)c1ccc2C(=O)N(Cc3ccc(cc3)S(N)(=O)=O)C(=O)c2c1 InChI=1S/C19H20N2O4S/c1-19(2,3)13-6-9-15-16(10-13)18(23)21(17(15)22)11-12-4-7-14(8-5-12)26(20,24)25/h4-10H,11H2,1-3H3,(H2,20,24,25) KZMYUJCSCDCHAA-UHFFFAOYSA-N 50035691 CHEMBL2377790 Prostaglandin G/H synthase 2 Ovis aries 50000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035691&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602471 313066687 CHEMBL2377790 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192966 NS(=O)(=O)c1ccc(CN2C(=O)c3c(C2=O)c(Cl)c(Cl)c(Cl)c3Cl)cc1 InChI=1S/C15H8Cl4N2O4S/c16-10-8-9(11(17)13(19)12(10)18)15(23)21(14(8)22)5-6-1-3-7(4-2-6)26(20,24)25/h1-4H,5H2,(H2,20,24,25) QANGVWSVBMPVJM-UHFFFAOYSA-N 50035673 CHEMBL2377796 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035673&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602476 313066670 CHEMBL2377796 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192968 NS(=O)(=O)c1ccc(CN2C(=O)[C@H]3CC=CC[C@H]3C2=O)cc1 InChI=1S/C15H16N2O4S/c16-22(20,21)11-7-5-10(6-8-11)9-17-14(18)12-3-1-2-4-13(12)15(17)19/h1-2,5-8,12-13H,3-4,9H2,(H2,16,20,21)/t12-,13+ DHQMCIMTRYMGID-BETUJISGSA-N 50035685 CHEMBL2377783 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035685&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602411 313066681 CHEMBL2377783 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192969 NS(=O)(=O)c1ccc(cc1)N1C(=O)CCC1=O InChI=1S/C10H10N2O4S/c11-17(15,16)8-3-1-7(2-4-8)12-9(13)5-6-10(12)14/h1-4H,5-6H2,(H2,11,15,16) CXYJOKAZIWXRHN-UHFFFAOYSA-N 50035687 CHEMBL2377781 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035687&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 79611 313066683 CHEMBL2377781 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192970 OC(=O)c1ccc(cc1)N1C(=O)c2c(C1=O)c(Cl)c(Cl)c(Cl)c2Cl InChI=1S/C15H5Cl4NO4/c16-9-7-8(10(17)12(19)11(9)18)14(22)20(13(7)21)6-3-1-5(2-4-6)15(23)24/h1-4H,(H,23,24) ISKWQHYKQGPESR-UHFFFAOYSA-N 50035675 CHEMBL2377771 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035675&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 983751 313066672 CHEMBL2377771 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192971 [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)/p-1 DCOPUUMXTXDBNB-UHFFFAOYSA-M 50174201 ARTHROTEC::GP 45840::SOLARAZE::Sodium; [2-(2,6-dichloro-phenylamino)-phenyl]-acetate::US11173137, Compound Diclofenac::VOLTAREN::VOLTAREN-XR::diclofenac sodium::sodium 2-(2-(2,6-dichlorophenylamino)phenyl)acetate Prostaglandin G/H synthase 2 Ovis aries 4200 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50174201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50174201&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 3032 104060023 4509 C01690 ZINC00001281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192975 OC(=O)c1ccc(cc1)N1C(=O)CCC1=O InChI=1S/C11H9NO4/c13-9-5-6-10(14)12(9)8-3-1-7(2-4-8)11(15)16/h1-4H,5-6H2,(H,15,16) ZFHIOWPHEFPSPA-UHFFFAOYSA-N 50035686 CHEMBL2377782 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035686&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 351361 313066682 CHEMBL2377782 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51187751 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 57 ChEMBL 10.1007/s00044-012-0244-2 10.7270/Q2C250B3 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51187752 COc1ccc(\C=C\C2=C(C(NC(=O)N2)c2ccc(OC)cc2)C(O)=O)cc1 InChI=1S/C21H20N2O5/c1-27-15-8-3-13(4-9-15)5-12-17-18(20(24)25)19(23-21(26)22-17)14-6-10-16(28-2)11-7-14/h3-12,19H,1-2H3,(H,24,25)(H2,22,23,26)/b12-5+ DBEKTLKGMNFWQP-LFYBBSHMSA-N 50488361 CHEMBL2281618 Prostaglandin G/H synthase 2 Ovis aries 48 ChEMBL 10.1007/s00044-012-0244-2 10.7270/Q2C250B3 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488361&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71722001 433955626 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51187754 COc1ccc(\C=C\C2=C(C(NC(=S)N2)c2ccc(OC)cc2)C(O)=O)cc1 InChI=1S/C21H20N2O4S/c1-26-15-8-3-13(4-9-15)5-12-17-18(20(24)25)19(23-21(28)22-17)14-6-10-16(27-2)11-7-14/h3-12,19H,1-2H3,(H,24,25)(H2,22,23,28)/b12-5+ UQSXRGKTUXAZOC-LFYBBSHMSA-N 50488362 CHEMBL2281619 Prostaglandin G/H synthase 2 Ovis aries 41 ChEMBL 10.1007/s00044-012-0244-2 10.7270/Q2C250B3 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488362&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71722005 433955627 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51193196 CC(C)(C)C1=CC(C=C(C1=O)C(C)(C)C)=NNC(=O)c1ccccc1 InChI=1S/C21H26N2O2/c1-20(2,3)16-12-15(13-17(18(16)24)21(4,5)6)22-23-19(25)14-10-8-7-9-11-14/h7-13H,1-6H3,(H,23,25) LJSCPVBDGOFMAT-UHFFFAOYSA-N 50491245 CHEMBL2380929 Prostaglandin G/H synthase 2 Ovis aries 9500 ChEMBL 10.1016/j.bmc.2013.02.033 10.7270/Q2H41VBV 23517721 Misra, S; Ghatak, S; Patil, N; Dandawate, P; Ambike, V; Adsule, S; Unni, D; Venkateswara Swamy, K; Padhye, S Medical University of South Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491245&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 3590533 433958510 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51193197 CC(C)(C)c1cc(\C=C2/SC(N)=NC2=O)cc(c1O)C(C)(C)C InChI=1S/C18H24N2O2S/c1-17(2,3)11-7-10(8-12(14(11)21)18(4,5)6)9-13-15(22)20-16(19)23-13/h7-9,21H,1-6H3,(H2,19,20,22)/b13-9- AKTXOQVMWSFEBQ-LCYFTJDESA-N 50491246 Darbufelone Prostaglandin G/H synthase 2 Ovis aries 480 ChEMBL 10.1016/j.bmc.2013.02.033 10.7270/Q2H41VBV 23517721 Misra, S; Ghatak, S; Patil, N; Dandawate, P; Ambike, V; Adsule, S; Unni, D; Venkateswara Swamy, K; Padhye, S Medical University of South Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491246&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6444826 433958511 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51193199 CC(C)(C)C1=CC(C=C(C1=O)C(C)(C)C)=NNC(=O)c1ccncc1 InChI=1S/C20H25N3O2/c1-19(2,3)15-11-14(12-16(17(15)24)20(4,5)6)22-23-18(25)13-7-9-21-10-8-13/h7-12H,1-6H3,(H,23,25) HCSMEIDSTDGNNY-UHFFFAOYSA-N 50491247 CHEMBL527577::TCMDC-123490 Prostaglandin G/H synthase 2 Ovis aries 7600 ChEMBL 10.1016/j.bmc.2013.02.033 10.7270/Q2H41VBV 23517721 Misra, S; Ghatak, S; Patil, N; Dandawate, P; Ambike, V; Adsule, S; Unni, D; Venkateswara Swamy, K; Padhye, S Medical University of South Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491247&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2189542 433958512 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51193201 CC(C)(C)C1=CC(C=C(C1=O)C(C)(C)C)=NNC(=O)c1cccnc1 InChI=1S/C20H25N3O2/c1-19(2,3)15-10-14(11-16(17(15)24)20(4,5)6)22-23-18(25)13-8-7-9-21-12-13/h7-12H,1-6H3,(H,23,25) MCYFPBQWTYELOJ-UHFFFAOYSA-N 50491244 CHEMBL2380930 Prostaglandin G/H synthase 2 Ovis aries 9300 ChEMBL 10.1016/j.bmc.2013.02.033 10.7270/Q2H41VBV 23517721 Misra, S; Ghatak, S; Patil, N; Dandawate, P; Ambike, V; Adsule, S; Unni, D; Venkateswara Swamy, K; Padhye, S Medical University of South Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50491244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50491244&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 914562 433958509 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189359 CS(=O)(=O)c1ccc(cc1)[C@@H]1[C@H](Oc2ccccc2)C(=O)N1c1ccc(Cl)cc1 InChI=1S/C22H18ClNO4S/c1-29(26,27)19-13-7-15(8-14-19)20-21(28-18-5-3-2-4-6-18)22(25)24(20)17-11-9-16(23)10-12-17/h2-14,20-21H,1H3/t20-,21+/m1/s1 OLGIBJSHMWDFOA-RTWAWAEBSA-N 50488925 CHEMBL2298394 Prostaglandin G/H synthase 2 Ovis aries 68 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488925&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76327765 433956190 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189360 CCCCCN1[C@@H]([C@H](Oc2ccccc2)C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C21H25NO4S/c1-3-4-8-15-22-19(16-11-13-18(14-12-16)27(2,24)25)20(21(22)23)26-17-9-6-5-7-10-17/h5-7,9-14,19-20H,3-4,8,15H2,1-2H3/t19-,20+/m1/s1 GEPFHSWMJJNRBR-UXHICEINSA-N 50488926 CHEMBL2298390 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488926&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76331417 433956191 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189363 CS(=O)(=O)c1ccc(cc1)[C@@H]1[C@H](Oc2ccccc2)C(=O)N1C1CCCCC1 InChI=1S/C22H25NO4S/c1-28(25,26)19-14-12-16(13-15-19)20-21(27-18-10-6-3-7-11-18)22(24)23(20)17-8-4-2-5-9-17/h3,6-7,10-15,17,20-21H,2,4-5,8-9H2,1H3/t20-,21+/m1/s1 SIGLNTNWQQHXFN-RTWAWAEBSA-N 50488929 CHEMBL2298391 Prostaglandin G/H synthase 2 Ovis aries 57 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488929&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76320554 433956194 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189365 COc1ccc(cc1)N1[C@@H]([C@H](Oc2ccccc2)C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C23H21NO5S/c1-28-18-12-10-17(11-13-18)24-21(16-8-14-20(15-9-16)30(2,26)27)22(23(24)25)29-19-6-4-3-5-7-19/h3-15,21-22H,1-2H3/t21-,22+/m1/s1 GIPJJKDAYCSIOL-YADHBBJMSA-N 50488924 CHEMBL2298524 Prostaglandin G/H synthase 2 Ovis aries 54 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488924&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76324218 433956189 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189366 Cc1ccc(cc1)N1[C@@H]([C@H](Oc2ccccc2)C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C23H21NO4S/c1-16-8-12-18(13-9-16)24-21(17-10-14-20(15-11-17)29(2,26)27)22(23(24)25)28-19-6-4-3-5-7-19/h3-15,21-22H,1-2H3/t21-,22+/m1/s1 BWNYGJPUEOVPHB-YADHBBJMSA-N 50488931 CHEMBL2298395 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488931&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76327766 433956196 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189367 CS(=O)(=O)c1ccc(cc1)[C@@H]1[C@H](Oc2ccccc2)C(=O)N1c1ccc(F)cc1 InChI=1S/C22H18FNO4S/c1-29(26,27)19-13-7-15(8-14-19)20-21(28-18-5-3-2-4-6-18)22(25)24(20)17-11-9-16(23)10-12-17/h2-14,20-21H,1H3/t20-,21+/m1/s1 JMDKUTQQCRLPKG-RTWAWAEBSA-N 50488928 CHEMBL2298393 Prostaglandin G/H synthase 2 Ovis aries 56 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488928&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76335016 433956193 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189368 CS(=O)(=O)c1ccc(cc1)[C@@H]1[C@H](Oc2ccccc2)C(=O)N1c1ccccc1 InChI=1S/C22H19NO4S/c1-28(25,26)19-14-12-16(13-15-19)20-21(27-18-10-6-3-7-11-18)22(24)23(20)17-8-4-2-5-9-17/h2-15,20-21H,1H3/t20-,21+/m1/s1 OBYCOCIOYZNVCP-RTWAWAEBSA-N 50488930 CHEMBL2298392 Prostaglandin G/H synthase 2 Ovis aries 72 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488930&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76309619 433956195 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189369 CCCCN1[C@@H]([C@H](Oc2ccccc2)C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C20H23NO4S/c1-3-4-14-21-18(15-10-12-17(13-11-15)26(2,23)24)19(20(21)22)25-16-8-6-5-7-9-16/h5-13,18-19H,3-4,14H2,1-2H3/t18-,19+/m1/s1 VBVLDHQWGISOJW-MOPGFXCFSA-N 50488932 CHEMBL2298389 Prostaglandin G/H synthase 2 Ovis aries 80 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488932&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76320553 433956197 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189370 CC(C)N1[C@@H]([C@H](Oc2ccccc2)C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H21NO4S/c1-13(2)20-17(14-9-11-16(12-10-14)25(3,22)23)18(19(20)21)24-15-7-5-4-6-8-15/h4-13,17-18H,1-3H3/t17-,18+/m1/s1 QGBAWXKTUGBPFG-MSOLQXFVSA-N 50488933 CHEMBL2298388 Prostaglandin G/H synthase 2 Ovis aries 84 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488933&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76331416 433956198 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189376 CCCN1[C@@H]([C@H](Oc2ccccc2)C1=O)c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H21NO4S/c1-3-13-20-17(14-9-11-16(12-10-14)25(2,22)23)18(19(20)21)24-15-7-5-4-6-8-15/h4-12,17-18H,3,13H2,1-2H3/t17-,18+/m1/s1 DWXKGZDXBKCCFJ-MSOLQXFVSA-N 50488927 CHEMBL2298387 Prostaglandin G/H synthase 2 Ovis aries 95 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488927&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 76327764 433956192 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51189378 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1007/s00044-012-0387-1 10.7270/Q2DR2ZDN n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51195976 COc1cc(\C=C\C(=O)c2c(O)cc(C)c(Cl)c2C)cc(OC)c1OC InChI=1S/C20H21ClO5/c1-11-8-15(23)18(12(2)19(11)21)14(22)7-6-13-9-16(24-3)20(26-5)17(10-13)25-4/h6-10,23H,1-5H3/b7-6+ GFCYNCSDFDPESB-VOTSOKGWSA-N 50492324 CHEMBL2402595 Prostaglandin G/H synthase 2 Ovis aries 87000 ChEMBL 10.1016/j.ejmech.2013.04.056 10.7270/Q2GM8B7G 23693150 Bano, S; Javed, K; Ahmad, S; Rathish, IG; Singh, S; Chaitanya, M; Arunasree, KM; Alam, MS Jamia Hamdard (Hamdard University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492324&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71741030 433959589 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51195977 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 480 ChEMBL 10.1016/j.ejmech.2013.04.056 10.7270/Q2GM8B7G 23693150 Bano, S; Javed, K; Ahmad, S; Rathish, IG; Singh, S; Chaitanya, M; Arunasree, KM; Alam, MS Jamia Hamdard (Hamdard University) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197161 COC1Oc2ccccc2-c2c1oc1c(OC)c(O)c(C)c(O)c1c2=O InChI=1S/C19H16O7/c1-8-13(20)12-15(22)11-9-6-4-5-7-10(9)25-19(24-3)17(11)26-16(12)18(23-2)14(8)21/h4-7,19-21H,1-3H3 JWYNDRGBQXDNPV-UHFFFAOYSA-N 50492736 CHEMBL2408964 Prostaglandin G/H synthase 2 Ovis aries 31400 ChEMBL 10.1021/np300899w 10.7270/Q2611381 23914900 Bairwa, K; Singh, IN; Roy, SK; Grover, J; Srivastava, A; Jachak, SM National Institute of Pharmaceutical Education and Research-NIPER http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492736&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 72190429 433960001 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197162 OC1Oc2cc(O)ccc2-c2c1oc1cc(O)cc(O)c1c2=O InChI=1S/C16H10O7/c17-6-1-2-8-10(4-6)23-16(21)15-12(8)14(20)13-9(19)3-7(18)5-11(13)22-15/h1-5,16-19,21H GEMHDCJCWRUUDD-UHFFFAOYSA-N 50492738 CHEMBL2408966 Prostaglandin G/H synthase 2 Ovis aries 25500 ChEMBL 10.1021/np300899w 10.7270/Q2611381 23914900 Bairwa, K; Singh, IN; Roy, SK; Grover, J; Srivastava, A; Jachak, SM National Institute of Pharmaceutical Education and Research-NIPER http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492738&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 72190431 433960003 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197175 NC(=S)c1ccc(cc1)-n1nc(cc1-c1ccco1)C(F)(F)F InChI=1S/C15H10F3N3OS/c16-15(17,18)13-8-11(12-2-1-7-22-12)21(20-13)10-5-3-9(4-6-10)14(19)23/h1-8H,(H2,19,23) QOMKEZLUCGAMMC-UHFFFAOYSA-N 50492743 CHEMBL2413419 Prostaglandin G/H synthase 2 Ovis aries 9070 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492743&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727535 433960008 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197176 COc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)C(N)=S)C(F)(F)F InChI=1S/C18H14F3N3OS/c1-25-14-8-4-11(5-9-14)15-10-16(18(19,20)21)23-24(15)13-6-2-12(3-7-13)17(22)26/h2-10H,1H3,(H2,22,26) AFARHEIZDYGPLQ-UHFFFAOYSA-N 50492744 CHEMBL2413430 Prostaglandin G/H synthase 2 Ovis aries 1940 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492744&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727532 433960009 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197177 NC(=S)c1ccc(cc1)-n1nc(cc1-c1ccc(Br)cc1)C(F)(F)F InChI=1S/C17H11BrF3N3S/c18-12-5-1-10(2-6-12)14-9-15(17(19,20)21)23-24(14)13-7-3-11(4-8-13)16(22)25/h1-9H,(H2,22,25) WDNPSNKOLYFIGV-UHFFFAOYSA-N 50492745 CHEMBL2413429 Prostaglandin G/H synthase 2 Ovis aries 2870 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492745&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727435 433960010 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197178 COc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)C#N)C(F)(F)F InChI=1S/C18H12F3N3O/c1-25-15-8-4-13(5-9-15)16-10-17(18(19,20)21)23-24(16)14-6-2-12(11-22)3-7-14/h2-10H,1H3 CGIFDCBIWRRZLD-UHFFFAOYSA-N 50492746 CHEMBL2413421 Prostaglandin G/H synthase 2 Ovis aries >30000 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492746&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 21090956 433960011 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197185 FC(F)(F)c1cc(-c2ccc(Br)cc2)n(n1)-c1ccc(cc1)C#N InChI=1S/C17H9BrF3N3/c18-13-5-3-12(4-6-13)15-9-16(17(19,20)21)23-24(15)14-7-1-11(10-22)2-8-14/h1-9H RRGORDHJLLMSHA-UHFFFAOYSA-N 50492750 CHEMBL2413420 Prostaglandin G/H synthase 2 Ovis aries 19220 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492750&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727325 433960015 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197186 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 150 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197188 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries >30000 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197189 NC(=S)c1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)(F)F InChI=1S/C17H11ClF3N3S/c18-12-5-1-10(2-6-12)14-9-15(17(19,20)21)23-24(14)13-7-3-11(4-8-13)16(22)25/h1-9H,(H2,22,25) BJNCMKBTDSALPM-UHFFFAOYSA-N 50492747 CHEMBL2413428 Prostaglandin G/H synthase 2 Ovis aries 1440 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492747&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727434 433960012 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197190 NC(=S)c1ccc(cc1)-n1nc(cc1-c1ccccc1)C(F)(F)F InChI=1S/C17H12F3N3S/c18-17(19,20)15-10-14(11-4-2-1-3-5-11)23(22-15)13-8-6-12(7-9-13)16(21)24/h1-10H,(H2,21,24) UAWUBIOHSLQWDB-UHFFFAOYSA-N 50492749 CHEMBL2413425 Prostaglandin G/H synthase 2 Ovis aries 23560 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492749&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727431 433960014 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197194 FC(F)(F)c1cc(-c2ccccc2)n(n1)-c1ccc(cc1)C#N InChI=1S/C17H10F3N3/c18-17(19,20)16-10-15(13-4-2-1-3-5-13)23(22-16)14-8-6-12(11-21)7-9-14/h1-10H YABDXTKSSATXMB-UHFFFAOYSA-N 50492752 CHEMBL2413433 Prostaglandin G/H synthase 2 Ovis aries >30000 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492752&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727322 433960017 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197197 NC(=S)c1ccc(cc1)-n1nc(cc1-c1ccc(F)cc1)C(F)(F)F InChI=1S/C17H11F4N3S/c18-12-5-1-10(2-6-12)14-9-15(17(19,20)21)23-24(14)13-7-3-11(4-8-13)16(22)25/h1-9H,(H2,22,25) UWBPJLSLAOHMJB-UHFFFAOYSA-N 50492751 CHEMBL2413427 Prostaglandin G/H synthase 2 Ovis aries 17430 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492751&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727433 433960016 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51197198 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)C(N)=S)C(F)(F)F InChI=1S/C18H14F3N3S/c1-11-2-4-12(5-3-11)15-10-16(18(19,20)21)23-24(15)14-8-6-13(7-9-14)17(22)25/h2-10H,1H3,(H2,22,25) DLUIPPLWXZORGW-UHFFFAOYSA-N 50492748 CHEMBL2413426 Prostaglandin G/H synthase 2 Ovis aries 7070 ChEMBL 10.1016/j.bmc.2013.05.029 10.7270/Q2SQ93B4 23769654 Chandna, N; Kumar, S; Kaushik, P; Kaushik, D; Roy, SK; Gupta, GK; Jachak, SM; Kapoor, JK; Sharma, PK Kurukshetra University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492748&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71727432 433960013 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192915 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 260 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192916 NS(=O)(=O)c1ccc(CN2C(=O)c3cccc4cccc(C2=O)c34)cc1 InChI=1S/C19H14N2O4S/c20-26(24,25)14-9-7-12(8-10-14)11-21-18(22)15-5-1-3-13-4-2-6-16(17(13)15)19(21)23/h1-10H,11H2,(H2,20,24,25) CNFAHVNPEUHGNP-UHFFFAOYSA-N 50035697 CHEMBL2377778 Prostaglandin G/H synthase 2 Ovis aries 3000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035697&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602540 313066692 CHEMBL2377778 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192917 OC(=O)c1ccc(cc1)N1C(=O)c2nccnc2C1=O InChI=1S/C13H7N3O4/c17-11-9-10(15-6-5-14-9)12(18)16(11)8-3-1-7(2-4-8)13(19)20/h1-6H,(H,19,20) XDAJHYFGFMWBOF-UHFFFAOYSA-N 50035695 CHEMBL2377777 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035695&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 4583704 313066691 CHEMBL2377777 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192918 NS(=O)(=O)c1ccc(CN2C(=O)c3nccnc3C2=O)cc1 InChI=1S/C13H10N4O4S/c14-22(20,21)9-3-1-8(2-4-9)7-17-12(18)10-11(13(17)19)16-6-5-15-10/h1-6H,7H2,(H2,14,20,21) RDIYOFSCIVXRIX-UHFFFAOYSA-N 50035679 CHEMBL2377775 Prostaglandin G/H synthase 2 Ovis aries 800 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035679&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602538 313066676 CHEMBL2377775 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192919 NS(=O)(=O)c1ccc(cc1)N1C(=O)c2ccc(cc2C1=O)[N+]([O-])=O InChI=1S/C14H9N3O6S/c15-24(22,23)10-4-1-8(2-5-10)16-13(18)11-6-3-9(17(20)21)7-12(11)14(16)19/h1-7H,(H2,15,22,23) ODIGCXXQQQBPBI-UHFFFAOYSA-N 50035677 CHEMBL2377773 Prostaglandin G/H synthase 2 Ovis aries 300 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035677&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 3133127 313066674 CHEMBL2377773 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192920 NS(=O)(=O)c1ccc(cc1)N1C(=O)c2c(C1=O)c(Cl)c(Cl)c(Cl)c2Cl InChI=1S/C14H6Cl4N2O4S/c15-9-7-8(10(16)12(18)11(9)17)14(22)20(13(7)21)5-1-3-6(4-2-5)25(19,23)24/h1-4H,(H2,19,23,24) VOULHARHCIQTLL-UHFFFAOYSA-N 50035674 CHEMBL2377770 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035674&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 13177311 313066671 CHEMBL2377770 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192921 OC(=O)c1ccc(cc1)N1C(=O)c2cc(Cl)c(Cl)cc2C1=O InChI=1S/C15H7Cl2NO4/c16-11-5-9-10(6-12(11)17)14(20)18(13(9)19)8-3-1-7(2-4-8)15(21)22/h1-6H,(H,21,22) YNOBZDKRXIQORN-UHFFFAOYSA-N 50035672 CHEMBL2377795 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035672&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 767467 313066669 CHEMBL2377795 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192922 CC(C)(C)c1ccc2C(=O)N(C(=O)c2c1)c1ccc(cc1)C(O)=O InChI=1S/C19H17NO4/c1-19(2,3)12-6-9-14-15(10-12)17(22)20(16(14)21)13-7-4-11(5-8-13)18(23)24/h4-10H,1-3H3,(H,23,24) QIZDHZMUNRZKRJ-UHFFFAOYSA-N 50035693 CHEMBL2377792 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035693&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 1211700 313066689 CHEMBL2377792 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192923 CC(C)(C)c1ccc2C(=O)N(C(=O)c2c1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C18H18N2O4S/c1-18(2,3)11-4-9-14-15(10-11)17(22)20(16(14)21)12-5-7-13(8-6-12)25(19,23)24/h4-10H,1-3H3,(H2,19,23,24) ARZLYRMAMRPNLV-UHFFFAOYSA-N 50035692 CHEMBL2377791 Prostaglandin G/H synthase 2 Ovis aries 50000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035692&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 71602472 313066688 CHEMBL2377791 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192924 Cc1ccc2C(=O)N(C(=O)c2c1)c1ccc(cc1)C(O)=O InChI=1S/C16H11NO4/c1-9-2-7-12-13(8-9)15(19)17(14(12)18)11-5-3-10(4-6-11)16(20)21/h2-8H,1H3,(H,20,21) HENFOGMTHOCWFJ-UHFFFAOYSA-N 50035690 CHEMBL2377789 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035690&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 1211699 313066686 CHEMBL2377789 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192925 Cc1ccc2C(=O)N(C(=O)c2c1)c1ccc(cc1)S(N)(=O)=O InChI=1S/C15H12N2O4S/c1-9-2-7-12-13(8-9)15(19)17(14(12)18)10-3-5-11(6-4-10)22(16,20)21/h2-8H,1H3,(H2,16,20,21) KQTVCJUOCVKUGE-UHFFFAOYSA-N 50035689 CHEMBL2377788 Prostaglandin G/H synthase 2 Ovis aries 50000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035689&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73350409 313066685 CHEMBL2377788 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192926 NS(=O)(=O)c1ccc(CN2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C15H12N2O4S/c16-22(20,21)11-7-5-10(6-8-11)9-17-14(18)12-3-1-2-4-13(12)15(17)19/h1-8H,9H2,(H2,16,20,21) RSINXGPYLWVADR-UHFFFAOYSA-N 50035682 CHEMBL2377786 Prostaglandin G/H synthase 2 Ovis aries 20000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035682&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 323350 313066678 CHEMBL2377786 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51192927 OC(=O)c1ccc(cc1)N1C(=O)[C@H]2CC=CC[C@H]2C1=O InChI=1S/C15H13NO4/c17-13-11-3-1-2-4-12(11)14(18)16(13)10-7-5-9(6-8-10)15(19)20/h1-2,5-8,11-12H,3-4H2,(H,19,20)/t11-,12+ XELUDRMLYBRSSE-TXEJJXNPSA-N 50035683 CHEMBL2377785 Prostaglandin G/H synthase 2 Ovis aries >100000 ChEMBL 10.1016/j.bmcl.2013.02.107 10.7270/Q2SJ1PHN 23528298 Al-Suwaidan, IA; Alanazi, AM; El-Azab, AS; Al-Obaid, AM; ElTahir, KE; Maarouf, AR; Abu El-Enin, MA; Abdel-Aziz, AA King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035683&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 702292 313066679 CHEMBL2377785 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51204700 CSc1nnc(-c2ccc(cc2)S(C)(=O)=O)c(n1)-c1ccc(C)cc1 InChI=1S/C18H17N3O2S2/c1-12-4-6-13(7-5-12)16-17(20-21-18(19-16)24-2)14-8-10-15(11-9-14)25(3,22)23/h4-11H,1-3H3 PKNUPUGKNKCISE-UHFFFAOYSA-N 50495222 CHEMBL3103782 Prostaglandin G/H synthase 2 Ovis aries 180 ChEMBL 10.1016/j.bmc.2013.12.002 10.7270/Q2319ZV3 24361187 Irannejad, H; Kebriaieezadeh, A; Zarghi, A; Montazer-Sadegh, F; Shafiee, A; Assadieskandar, A; Amini, M Mazandaran University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50495222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50495222&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73334667 433962487 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51204702 COc1ccc(cc1)-c1nc(SC)nnc1-c1ccc(cc1)S(C)(=O)=O InChI=1S/C18H17N3O3S2/c1-24-14-8-4-12(5-9-14)16-17(20-21-18(19-16)25-2)13-6-10-15(11-7-13)26(3,22)23/h4-11H,1-3H3 ATDQDQLMBRWASH-UHFFFAOYSA-N 50495223 CHEMBL3103779 Prostaglandin G/H synthase 2 Ovis aries 170 ChEMBL 10.1016/j.bmc.2013.12.002 10.7270/Q2319ZV3 24361187 Irannejad, H; Kebriaieezadeh, A; Zarghi, A; Montazer-Sadegh, F; Shafiee, A; Assadieskandar, A; Amini, M Mazandaran University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50495223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50495223&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73334567 433962488 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51204703 CSc1nnc(-c2ccc(cc2)S(C)(=O)=O)c(n1)-c1ccc(F)cc1 InChI=1S/C17H14FN3O2S2/c1-24-17-19-15(11-3-7-13(18)8-4-11)16(20-21-17)12-5-9-14(10-6-12)25(2,22)23/h3-10H,1-2H3 BFZUEWTTWCIRBM-UHFFFAOYSA-N 50495224 CHEMBL3103781 Prostaglandin G/H synthase 2 Ovis aries 150 ChEMBL 10.1016/j.bmc.2013.12.002 10.7270/Q2319ZV3 24361187 Irannejad, H; Kebriaieezadeh, A; Zarghi, A; Montazer-Sadegh, F; Shafiee, A; Assadieskandar, A; Amini, M Mazandaran University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50495224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50495224&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73334566 433962489 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51204704 CSc1nnc(-c2ccc(cc2)S(C)(=O)=O)c(n1)-c1ccc(Cl)cc1 InChI=1S/C17H14ClN3O2S2/c1-24-17-19-15(11-3-7-13(18)8-4-11)16(20-21-17)12-5-9-14(10-6-12)25(2,22)23/h3-10H,1-2H3 ODAPOIHAXWDMLE-UHFFFAOYSA-N 50495225 CHEMBL3103780 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.bmc.2013.12.002 10.7270/Q2319ZV3 24361187 Irannejad, H; Kebriaieezadeh, A; Zarghi, A; Montazer-Sadegh, F; Shafiee, A; Assadieskandar, A; Amini, M Mazandaran University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50495225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50495225&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73334565 433962490 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51204705 CSc1nnc(-c2ccc(cc2)S(C)(=O)=O)c(n1)-c1ccccc1 InChI=1S/C17H15N3O2S2/c1-23-17-18-15(12-6-4-3-5-7-12)16(19-20-17)13-8-10-14(11-9-13)24(2,21)22/h3-11H,1-2H3 BBTYLLKCHFAWIF-UHFFFAOYSA-N 50495226 CHEMBL3103783 Prostaglandin G/H synthase 2 Ovis aries 190 ChEMBL 10.1016/j.bmc.2013.12.002 10.7270/Q2319ZV3 24361187 Irannejad, H; Kebriaieezadeh, A; Zarghi, A; Montazer-Sadegh, F; Shafiee, A; Assadieskandar, A; Amini, M Mazandaran University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50495226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50495226&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 73334451 433962491 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51204708 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmc.2013.12.002 10.7270/Q2319ZV3 24361187 Irannejad, H; Kebriaieezadeh, A; Zarghi, A; Montazer-Sadegh, F; Shafiee, A; Assadieskandar, A; Amini, M Mazandaran University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51206021 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 280 ChEMBL 10.1016/j.ejmech.2013.12.023 10.7270/Q2SF305M 24531199 Vitale, P; Perrone, MG; Malerba, P; Lavecchia, A; Scilimati, A University of Bari "A. Moro" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51206029 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 4200 ChEMBL 10.1016/j.ejmech.2013.12.023 10.7270/Q2SF305M 24531199 Vitale, P; Perrone, MG; Malerba, P; Lavecchia, A; Scilimati, A University of Bari "A. Moro" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252627 Cc1cc(-c2ccccc2)n(n1)C(=O)C(N1C(=O)c2ccccc2S1(=O)=O)C(=O)n1nc(C)cc1-c1ccccc1 InChI=1S/C30H23N5O5S/c1-19-17-24(21-11-5-3-6-12-21)33(31-19)29(37)27(35-28(36)23-15-9-10-16-26(23)41(35,39)40)30(38)34-25(18-20(2)32-34)22-13-7-4-8-14-22/h3-18,27H,1-2H3 SETSXTRBUALZTE-UHFFFAOYSA-N 50512155 CHEMBL4582722 Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512155&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155561899 440720737 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252636 Nn1c(S)nnc1-c1ccccc1S(=O)(=O)NCc1ccccc1 InChI=1S/C15H15N5O2S2/c16-20-14(18-19-15(20)23)12-8-4-5-9-13(12)24(21,22)17-10-11-6-2-1-3-7-11/h1-9,17H,10,16H2,(H,19,23) CKXCTDNPVGVMSU-UHFFFAOYSA-N 50512164 CHEMBL4536217 Prostaglandin G/H synthase 2 Ovis aries 230 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512164&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155548106 440720746 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252637 Sc1nnc(-c2ccccc2S(=O)(=O)NCc2ccccc2)n1\N=C\c1ccccc1 InChI=1S/C22H19N5O2S2/c28-31(29,24-16-18-11-5-2-6-12-18)20-14-8-7-13-19(20)21-25-26-22(30)27(21)23-15-17-9-3-1-4-10-17/h1-15,24H,16H2,(H,26,30)/b23-15+ YAQBNVNYLHGFKP-HZHRSRAPSA-N 50512154 CHEMBL4546681 Prostaglandin G/H synthase 2 Ovis aries 530 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512154&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155552151 440720736 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252638 Sc1nnc(-c2ccccc2S(=O)(=O)NCc2ccccc2)n1\N=C\c1ccc(Br)cc1 InChI=1S/C22H18BrN5O2S2/c23-18-12-10-17(11-13-18)14-24-28-21(26-27-22(28)31)19-8-4-5-9-20(19)32(29,30)25-15-16-6-2-1-3-7-16/h1-14,25H,15H2,(H,27,31)/b24-14+ FSILUXZMSXESHT-ZVHZXABRSA-N 50512158 CHEMBL4440760 Prostaglandin G/H synthase 2 Ovis aries 380 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512158&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155514801 440720740 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252639 COc1ccc(\C=N\n2c(S)nnc2-c2ccccc2S(=O)(=O)NCc2ccccc2)cc1 InChI=1S/C23H21N5O3S2/c1-31-19-13-11-18(12-14-19)15-24-28-22(26-27-23(28)32)20-9-5-6-10-21(20)33(29,30)25-16-17-7-3-2-4-8-17/h2-15,25H,16H2,1H3,(H,27,32)/b24-15+ VZMSIUKHXRSPSY-BUVRLJJBSA-N 50512159 CHEMBL4451727 Prostaglandin G/H synthase 2 Ovis aries 470 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512159&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155522240 440720741 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252640 CC(C)NS(=O)(=O)c1ccccc1C(=O)n1nc(C)cc1-c1ccccc1 InChI=1S/C20H21N3O3S/c1-14(2)22-27(25,26)19-12-8-7-11-17(19)20(24)23-18(13-15(3)21-23)16-9-5-4-6-10-16/h4-14,22H,1-3H3 IHLULQPNWKSKNZ-UHFFFAOYSA-N 50512160 CHEMBL4554694 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512160&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155556415 440720742 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252641 Fc1ccc(\C=N\NC(=O)C(N2C(=O)c3ccccc3S2(=O)=O)C(=O)N\N=C\c2ccc(F)cc2)cc1 InChI=1S/C24H17F2N5O5S/c25-17-9-5-15(6-10-17)13-27-29-22(32)21(23(33)30-28-14-16-7-11-18(26)12-8-16)31-24(34)19-3-1-2-4-20(19)37(31,35)36/h1-14,21H,(H,29,32)(H,30,33)/b27-13+,28-14+ FWBQOZBRJWWAJN-OCHFTUDZSA-N 50512162 CHEMBL4483027 Prostaglandin G/H synthase 2 Ovis aries 120 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512162&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155539974 440720744 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252642 Clc1ccc(\C=N\NC(=O)C(N2C(=O)c3ccccc3S2(=O)=O)C(=O)N\N=C\c2ccc(Cl)cc2)cc1 InChI=1S/C24H17Cl2N5O5S/c25-17-9-5-15(6-10-17)13-27-29-22(32)21(23(33)30-28-14-16-7-11-18(26)12-8-16)31-24(34)19-3-1-2-4-20(19)37(31,35)36/h1-14,21H,(H,29,32)(H,30,33)/b27-13+,28-14+ KTRDQCWNYCBFLW-OCHFTUDZSA-N 50512163 CHEMBL4453713 Prostaglandin G/H synthase 2 Ovis aries 610 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512163&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155522811 440720745 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252644 Sc1nnc(o1)-c1ccccc1S(=O)(=O)NCc1ccccc1 InChI=1S/C15H13N3O3S2/c19-23(20,16-10-11-6-2-1-3-7-11)13-9-5-4-8-12(13)14-17-18-15(22)21-14/h1-9,16H,10H2,(H,18,22) AYEJGGHTKVRWMX-UHFFFAOYSA-N 50512156 CHEMBL4538703 Prostaglandin G/H synthase 2 Ovis aries 520 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512156&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155548811 440720738 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252645 CC(C)NS(=O)(=O)c1ccccc1C(=O)N1N=C(CC1=O)c1ccccc1 InChI=1S/C19H19N3O4S/c1-13(2)21-27(25,26)17-11-7-6-10-15(17)19(24)22-18(23)12-16(20-22)14-8-4-3-5-9-14/h3-11,13,21H,12H2,1-2H3 RAXNKYKXORWLNN-UHFFFAOYSA-N 50512165 CHEMBL4569545 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512165&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155550654 440720747 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252648 O=S(=O)(NCc1ccccc1)c1ccccc1-c1nnc(SCc2ccccc2)o1 InChI=1S/C22H19N3O3S2/c26-30(27,23-15-17-9-3-1-4-10-17)20-14-8-7-13-19(20)21-24-25-22(28-21)29-16-18-11-5-2-6-12-18/h1-14,23H,15-16H2 URELNCVQYCCURB-UHFFFAOYSA-N 50512167 CHEMBL4442875 Prostaglandin G/H synthase 2 Ovis aries 390 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512167&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155516199 440720749 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252649 Sc1nnc(-c2ccccc2S(=O)(=O)NCc2ccccc2)n1\N=C\c1ccc(Cl)cc1 InChI=1S/C22H18ClN5O2S2/c23-18-12-10-17(11-13-18)14-24-28-21(26-27-22(28)31)19-8-4-5-9-20(19)32(29,30)25-15-16-6-2-1-3-7-16/h1-14,25H,15H2,(H,27,31)/b24-14+ GDQNCUBECPBLHJ-ZVHZXABRSA-N 50512166 CHEMBL4562177 Prostaglandin G/H synthase 2 Ovis aries 650 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512166&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155559033 440720748 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252650 O=C(N\N=C\c1ccccc1)C(N1C(=O)c2ccccc2S1(=O)=O)C(=O)N\N=C\c1ccccc1 InChI=1S/C24H19N5O5S/c30-22(27-25-15-17-9-3-1-4-10-17)21(23(31)28-26-16-18-11-5-2-6-12-18)29-24(32)19-13-7-8-14-20(19)35(29,33)34/h1-16,21H,(H,27,30)(H,28,31)/b25-15+,26-16+ MJTAIJKIQBWBCR-RYQLWAFASA-N 50512161 CHEMBL4472378 Prostaglandin G/H synthase 2 Ovis aries 290 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512161&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155535759 440720743 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252651 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51252653 CCSc1nnc(o1)-c1ccccc1S(=O)(=O)NCc1ccccc1 InChI=1S/C17H17N3O3S2/c1-2-24-17-20-19-16(23-17)14-10-6-7-11-15(14)25(21,22)18-12-13-8-4-3-5-9-13/h3-11,18H,2,12H2,1H3 QFNYLGWLXRAGSC-UHFFFAOYSA-N 50512157 CHEMBL4573574 Prostaglandin G/H synthase 2 Ovis aries 710 ChEMBL 10.1016/j.ejmech.2019.03.042 10.7270/Q24T6NP7 30928709 Taher, ES; Ibrahim, TS; Fares, M; Al-Mahmoudy, AMM; Radwan, AF; Orabi, KY; El-Sabbagh, OI Al-Azhar University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50512157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50512157&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155563588 440720739 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245746 Cl.Cc1ccc(cc1)-n1cc(COc2ccc(\C=N\Nc3c4CCCCc4nc4ccccc34)cc2)nn1 InChI=1S/C30H28N6O.ClH/c1-21-10-14-24(15-11-21)36-19-23(33-35-36)20-37-25-16-12-22(13-17-25)18-31-34-30-26-6-2-4-8-28(26)32-29-9-5-3-7-27(29)30;/h2,4,6,8,10-19H,3,5,7,9,20H2,1H3,(H,32,34);1H/b31-18+; YBGWJPILCGRFJW-PYDDSSFOSA-N 50509701 CHEMBL4592037 Prostaglandin G/H synthase 2 Ovis aries 61 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509701&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155569041 440718286 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245751 Cl.Brc1ccc(cc1)-n1cc(COc2ccc(\C=N\Nc3c4CCCCc4nc4ccccc34)cc2)nn1 InChI=1S/C29H25BrN6O.ClH/c30-21-11-13-23(14-12-21)36-18-22(33-35-36)19-37-24-15-9-20(10-16-24)17-31-34-29-25-5-1-3-7-27(25)32-28-8-4-2-6-26(28)29;/h1,3,5,7,9-18H,2,4,6,8,19H2,(H,32,34);1H/b31-17+; FTVVNLRUNUGQAH-DCJTZURGSA-N 50509706 CHEMBL4526428 Prostaglandin G/H synthase 2 Ovis aries 41 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509706&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155544057 440718291 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245752 S=C(NCc1ccccc1)NNc1c2CCCCc2nc2ccccc12 InChI=1S/C21H22N4S/c26-21(22-14-15-8-2-1-3-9-15)25-24-20-16-10-4-6-12-18(16)23-19-13-7-5-11-17(19)20/h1-4,6,8-10,12H,5,7,11,13-14H2,(H,23,24)(H2,22,25,26) GHGXCYPXBDQVRC-UHFFFAOYSA-N 50509708 CHEMBL4458648 Prostaglandin G/H synthase 2 Ovis aries 110 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509708&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155526939 440718293 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245753 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245754 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 490 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239387 CC1N(C)OC(=C1c1ccc(F)cc1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C18H18FNO3S/c1-12-17(13-4-8-15(19)9-5-13)18(23-20(12)2)14-6-10-16(11-7-14)24(3,21)22/h4-12H,1-3H3 CARDZWUJKAFXIX-UHFFFAOYSA-N 50103314 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2,3-dimethyl-2,3-dihydro-isoxazole::CHEMBL322240 Prostaglandin G/H synthase 2 Ovis aries 32 ChEMBL 10.1016/j.ejmech.2018.10.054 10.7270/Q2FX7DSW 30396033 Ramajayam, R The M.S University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103314&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10020588 103999613 CHEMBL322240 ZINC03940663 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239402 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)N=[N+]=[N-])C(F)(F)F InChI=1S/C17H12F3N5/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)23-25(15)14-8-6-13(7-9-14)22-24-21/h2-10H,1H3 UBOLXNPTLLXANI-UHFFFAOYSA-N 50103509 1-(4-Azido-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-pyrazole::CHEMBL104502 Prostaglandin G/H synthase 2 Ovis aries 1550 ChEMBL 10.1016/j.ejmech.2018.10.054 10.7270/Q2FX7DSW 30396033 Ramajayam, R The M.S University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103509&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10472597 103999713 CHEMBL104502 ZINC13863990 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239403 [N-]=[N+]=Nc1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 InChI=1S/C16H11N3O2/c17-19-18-13-8-6-11(7-9-13)14-10-21-16(20)15(14)12-4-2-1-3-5-12/h1-9H,10H2 APCWFZNDCFEDOA-UHFFFAOYSA-N 50103510 4-(4-Azido-phenyl)-3-phenyl-5H-furan-2-one::CHEMBL102223 Prostaglandin G/H synthase 2 Ovis aries 196 ChEMBL 10.1016/j.ejmech.2018.10.054 10.7270/Q2FX7DSW 30396033 Ramajayam, R The M.S University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103510&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10084869 103999714 CHEMBL102223 ZINC13863991 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239418 CCOc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1 InChI=1S/C20H18O5S/c1-3-24-18-13-17(14-7-5-4-6-8-14)19(20(21)25-18)15-9-11-16(12-10-15)26(2,22)23/h4-13H,3H2,1-2H3 CXFWNCNJNGMYQT-UHFFFAOYSA-N 50129503 6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL71200 Prostaglandin G/H synthase 2 Ovis aries 1300 ChEMBL 10.1016/j.ejmech.2018.10.054 10.7270/Q2FX7DSW 30396033 Ramajayam, R The M.S University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129503&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 11462842 104021086 CHEMBL71200 ZINC13528590 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51243657 CC[C@@H](\C=C\[C@@H](C)[C@H]1CC[C@H]2C3=CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-9,11,19-23,25-27,30H,7,10,12-18H2,1-6H3/b9-8+/t20-,21+,22+,23+,25-,26+,27+,28+,29-/m1/s1 JZVFJDZBLUFKCA-INYURWPISA-N 50508997 CHEMBL4538181 Prostaglandin G/H synthase 2 Ovis aries 7800 ChEMBL 10.1016/j.ejmech.2019.07.040 10.7270/Q2222Z25 31401465 Rodríguez-Soacha, DA; Scheiner, M; Decker, M Julius Maximilian University of W£rzburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50508997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50508997&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5283663 440717582 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239679 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 540 ChEMBL 10.1016/j.ejmech.2018.11.027 10.7270/Q2DZ0CMM 30469039 Marín-Ocampo, L; Veloza, LA; Abonia, R; Sepúlveda-Arias, JC Universidad Tecnol£gica de Pereira http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239685 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 3670 ChEMBL 10.1016/j.ejmech.2018.11.027 10.7270/Q2DZ0CMM 30469039 Marín-Ocampo, L; Veloza, LA; Abonia, R; Sepúlveda-Arias, JC Universidad Tecnol£gica de Pereira http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239686 Clc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C24H17ClN6O2/c25-18-11-13-19(14-12-18)26-23-29-28-20(33-23)15-31-24(32)27-21(16-7-3-1-4-8-16)22(30-31)17-9-5-2-6-10-17/h1-14H,15H2,(H,26,29) UWWQNKCREVHKKT-UHFFFAOYSA-N 198172 2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3d) Prostaglandin G/H synthase 2 Ovis aries 600 ChEMBL 10.1016/j.ejmech.2018.11.027 10.7270/Q2DZ0CMM 30469039 Marín-Ocampo, L; Veloza, LA; Abonia, R; Sepúlveda-Arias, JC Universidad Tecnol£gica de Pereira http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198172&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198620 318489244 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239687 COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C25H20N6O3/c1-33-20-14-12-19(13-15-20)26-24-29-28-21(34-24)16-31-25(32)27-22(17-8-4-2-5-9-17)23(30-31)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,26,29) STOZTMZCUWJXDR-UHFFFAOYSA-N 198171 2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3c) Prostaglandin G/H synthase 2 Ovis aries 600 ChEMBL 10.1016/j.ejmech.2018.11.027 10.7270/Q2DZ0CMM 30469039 Marín-Ocampo, L; Veloza, LA; Abonia, R; Sepúlveda-Arias, JC Universidad Tecnol£gica de Pereira http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198171&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198619 318489243 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239688 O=c1nc(-c2ccccc2)c(nn1Cc1nnc(Nc2ccccc2)o1)-c1ccccc1 InChI=1S/C24H18N6O2/c31-24-26-21(17-10-4-1-5-11-17)22(18-12-6-2-7-13-18)29-30(24)16-20-27-28-23(32-20)25-19-14-8-3-9-15-19/h1-15H,16H2,(H,25,28) OIANUMKKTLMDKM-UHFFFAOYSA-N 50507265 CHEMBL4536074 Prostaglandin G/H synthase 2 Ovis aries 600 ChEMBL 10.1016/j.ejmech.2018.11.027 10.7270/Q2DZ0CMM 30469039 Marín-Ocampo, L; Veloza, LA; Abonia, R; Sepúlveda-Arias, JC Universidad Tecnol£gica de Pereira http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50507265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50507265&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155548629 440715850 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239690 [O-][N+](=O)c1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C24H17N7O4/c32-24-26-21(16-7-3-1-4-8-16)22(17-9-5-2-6-10-17)29-30(24)15-20-27-28-23(35-20)25-18-11-13-19(14-12-18)31(33)34/h1-14H,15H2,(H,25,28) SIIQMKKTVDYUCD-UHFFFAOYSA-N 198173 2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3e) Prostaglandin G/H synthase 2 Ovis aries 600 ChEMBL 10.1016/j.ejmech.2018.11.027 10.7270/Q2DZ0CMM 30469039 Marín-Ocampo, L; Veloza, LA; Abonia, R; Sepúlveda-Arias, JC Universidad Tecnol£gica de Pereira http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198173&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198621 318489245 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51239691 Cc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C25H20N6O2/c1-17-12-14-20(15-13-17)26-24-29-28-21(33-24)16-31-25(32)27-22(18-8-4-2-5-9-18)23(30-31)19-10-6-3-7-11-19/h2-15H,16H2,1H3,(H,26,29) HTQSWIAIGAFUSA-UHFFFAOYSA-N 50507267 CHEMBL4444061 Prostaglandin G/H synthase 2 Ovis aries 600 ChEMBL 10.1016/j.ejmech.2018.11.027 10.7270/Q2DZ0CMM 30469039 Marín-Ocampo, L; Veloza, LA; Abonia, R; Sepúlveda-Arias, JC Universidad Tecnol£gica de Pereira http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50507267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50507267&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155517025 440715852 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245801 Cl.Clc1ccc(cc1)-n1cc(COc2ccc(\C=N\Nc3c4CCCCc4nc4ccccc34)cc2)nn1 InChI=1S/C29H25ClN6O.ClH/c30-21-11-13-23(14-12-21)36-18-22(33-35-36)19-37-24-15-9-20(10-16-24)17-31-34-29-25-5-1-3-7-27(25)32-28-8-4-2-6-26(28)29;/h1,3,5,7,9-18H,2,4,6,8,19H2,(H,32,34);1H/b31-17+; JDGKIDASPZLAPL-DCJTZURGSA-N 50509704 CHEMBL4443988 Prostaglandin G/H synthase 2 Ovis aries 43 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509704&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155516605 440718289 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245804 Cl.COc1ccc(cc1)-n1cc(COc2ccc(\C=N\Nc3c4CCCCc4nc4ccccc34)cc2)nn1 InChI=1S/C30H28N6O2.ClH/c1-37-24-16-12-23(13-17-24)36-19-22(33-35-36)20-38-25-14-10-21(11-15-25)18-31-34-30-26-6-2-4-8-28(26)32-29-9-5-3-7-27(29)30;/h2,4,6,8,10-19H,3,5,7,9,20H2,1H3,(H,32,34);1H/b31-18+; AVRHOZJIMGJSDK-PYDDSSFOSA-N 50509707 CHEMBL4553902 Prostaglandin G/H synthase 2 Ovis aries 74 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509707&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155555576 440718292 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51245805 OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19) DCOPUUMXTXDBNB-UHFFFAOYSA-N 13066 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid::CHEMBL139::Diclofenac::US11337935, Compound Diclofenac::US11478464, Compound Diclofenac::{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid Prostaglandin G/H synthase 2 Ovis aries 800 ChEMBL 10.1016/j.ejmech.2019.02.012 10.7270/Q2V69NVX 30771604 AlFadly, ED; Elzahhar, PA; Tramarin, A; Elkazaz, S; Shaltout, H; Abu-Serie, MM; Janockova, J; Soukup, O; Ghareeb, DA; El-Yazbi, AF; Rafeh, RW; Bakkar, NZ; Kobeissy, F; Iriepa, I; Moraleda, I; Saudi, MNS; Bartolini, M; Belal, ASF Alexandria University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13066&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search DIF 1NR6,5U1R,3N8Y,1SV9,3CFQ,4OJ4,4XTA,2WEK,1DVX,8BSG,1PXX,5DBY,2B17,3IB0,4ZBQ,4ZBR,4Z69,4UBS,6HN0,6HN1 3033 46513484 47381 CHEMBL139 DB00586 2714 C01690 ZINC00001281 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51285706 CC(=O)NS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccc(cc1)S(C)(=O)=O InChI=1S/C19H17NO7S2/c1-12(21)20-29(25,26)16-9-3-13(4-10-16)17-11-27-19(22)18(17)14-5-7-15(8-6-14)28(2,23)24/h3-10H,11H2,1-2H3,(H,20,21) BRCUVPAXYQULRV-UHFFFAOYSA-N 50143486 CHEMBL366422::N-Acetyl-4-[4-(4-methanesulfonyl-phenyl)-5-oxo-2,5-dihydro-furan-3-yl]-benzenesulfonamide Prostaglandin G/H synthase 2 Ovis aries 50 ChEMBL 10.1016/j.ejmech.2019.03.021 10.7270/Q2X92FQN 30909021 Husain, A; Khan, SA; Iram, F; Iqbal, MA; Asif, M Jamia Hamdard http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143486&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10003092 104032680 CHEMBL366422 ZINC28089817 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51319923 FC(F)(F)c1cccc(c1)N1CCN(Cc2ccc3OCCOc3c2)CC1 InChI=1S/C20H21F3N2O2/c21-20(22,23)16-2-1-3-17(13-16)25-8-6-24(7-9-25)14-15-4-5-18-19(12-15)27-11-10-26-18/h1-5,12-13H,6-11,14H2 BWLSPMQJSCACLH-UHFFFAOYSA-N 50534148 CHEMBL4524501 Prostaglandin G/H synthase 2 Ovis aries 120 ChEMBL 10.1016/j.bmc.2016.09.023 10.7270/Q20V8H9H 27658794 Sun, J; Wang, S; Sheng, GH; Lian, ZM; Liu, HY; Zhu, HL Shandong University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50534148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50534148&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 2845193 440742730 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51319924 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 40 ChEMBL 10.1016/j.bmc.2016.09.023 10.7270/Q20V8H9H 27658794 Sun, J; Wang, S; Sheng, GH; Lian, ZM; Liu, HY; Zhu, HL Shandong University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51319925 OC(=O)\C=C\c1ccc2O[C@H]([C@H](Oc2c1)c1cc(O)cc(O)c1)C(O)=O InChI=1S/C18H14O8/c19-11-6-10(7-12(20)8-11)16-17(18(23)24)25-13-3-1-9(2-4-15(21)22)5-14(13)26-16/h1-8,16-17,19-20H,(H,21,22)(H,23,24)/b4-2+/t16-,17-/m1/s1 DCEUKJMFFBNQJQ-HTYNWGMWSA-N 50362661 CHEMBL1939435 Prostaglandin G/H synthase 2 Ovis aries 7500 ChEMBL 10.1016/j.bmc.2016.09.023 10.7270/Q20V8H9H 27658794 Sun, J; Wang, S; Sheng, GH; Lian, ZM; Liu, HY; Zhu, HL Shandong University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362661&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 56951565 136966723 CHEMBL1939435 ZINC73240659 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296360 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)cc3)O[C@H](CO)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@H]1O InChI=1S/C34H44O18/c1-16-24(41)28(51-33-30(44)34(45,14-36)15-47-33)25(42)32(48-16)52-29-26(43)31(46-11-10-17-2-6-19(37)7-3-17)49-22(13-35)27(29)50-23(40)9-5-18-4-8-20(38)21(39)12-18/h2-9,12,16,22,24-33,35-39,41-45H,10-11,13-15H2,1H3/b9-5+/t16-,22+,24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+/m0/s1 WQVJDAHWKMESAS-MOSLXDOWSA-N 50528353 CHEMBL4576547 Prostaglandin G/H synthase 2 Ovis aries 36000 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528353&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155554047 440736935 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296363 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O[C@@H]3OC[C@](O)(CO)[C@H]3O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C34H44O19/c1-15-24(42)25(43)26(44)31(49-15)52-28-27(51-23(41)7-4-16-2-5-18(37)20(39)10-16)22(12-35)50-32(47-9-8-17-3-6-19(38)21(40)11-17)29(28)53-33-30(45)34(46,13-36)14-48-33/h2-7,10-11,15,22,24-33,35-40,42-46H,8-9,12-14H2,1H3/b7-4+/t15-,22+,24-,25+,26+,27+,28-,29+,30-,31-,32+,33-,34+/m0/s1 UXPCJXXUGGXVGI-PQYLUDDISA-N 50528356 CHEMBL4467432 Prostaglandin G/H synthase 2 Ovis aries 18200 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528356&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 102019408 440736938 C02757 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296365 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O[C@@H]3OC[C@](O)(CO)[C@H]3O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](COC(C)=O)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C36H46O20/c1-16-26(44)27(45)28(46)33(52-16)55-30-29(54-25(43)8-5-18-3-6-20(39)22(41)11-18)24(13-50-17(2)38)53-34(49-10-9-19-4-7-21(40)23(42)12-19)31(30)56-35-32(47)36(48,14-37)15-51-35/h3-8,11-12,16,24,26-35,37,39-42,44-48H,9-10,13-15H2,1-2H3/b8-5+/t16-,24+,26-,27+,28+,29+,30-,31+,32-,33-,34+,35-,36+/m0/s1 CHCBSUXEBKZFGJ-RLCKCSFISA-N 50528357 CHEMBL4530118 Prostaglandin G/H synthase 2 Ovis aries 16000 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528357&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155545808 440736939 C02757 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296368 CC(C)C(=O)c1c(O)cc(O)c(C\C=C(/C)CCC=C(C)C)c1O InChI=1S/C20H28O4/c1-12(2)7-6-8-14(5)9-10-15-16(21)11-17(22)18(20(15)24)19(23)13(3)4/h7,9,11,13,21-22,24H,6,8,10H2,1-5H3/b14-9+ TXDNBNXWWCEVMG-NTEUORMPSA-N 50528359 CHEMBL524326 Prostaglandin G/H synthase 2 Ovis aries 29900000 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528359&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10426888 440736941 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296374 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 710000 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296380 OC[C@H]1O[C@@H](Oc2ccc(O)c(O)c2)[C@H](O[C@@H]2OC[C@](O)(COC(=O)c3ccc(O)c(O)c3)[C@H]2O)[C@@H](O)[C@@H]1O InChI=1S/C24H28O15/c25-7-16-17(30)18(31)19(22(38-16)37-11-2-4-13(27)15(29)6-11)39-23-20(32)24(34,9-36-23)8-35-21(33)10-1-3-12(26)14(28)5-10/h1-6,16-20,22-23,25-32,34H,7-9H2/t16-,17-,18+,19-,20+,22-,23+,24-/m1/s1 CPLPOIPKVDPNOQ-JALRXJJFSA-N 50528368 CHEMBL4465765 Prostaglandin G/H synthase 2 Ovis aries 24700 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528368&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155531339 440736950 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296381 CCOC(=O)[C@H](CO)NC(=O)c1cccc(O)c1O InChI=1S/C12H15NO6/c1-2-19-12(18)8(6-14)13-11(17)7-4-3-5-9(15)10(7)16/h3-5,8,14-16H,2,6H2,1H3,(H,13,17)/t8-/m0/s1 ZNAULGVROLOSBS-QMMMGPOBSA-N 50528369 CHEMBL4472111 Prostaglandin G/H synthase 2 Ovis aries 2800000 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 139588023 440736951 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296383 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](COC(C)=O)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@H]1O InChI=1S/C36H46O20/c1-16-26(44)30(55-35-32(47)36(48,14-37)15-51-35)27(45)34(52-16)56-31-28(46)33(49-10-9-19-4-7-21(40)23(42)12-19)53-24(13-50-17(2)38)29(31)54-25(43)8-5-18-3-6-20(39)22(41)11-18/h3-8,11-12,16,24,26-35,37,39-42,44-48H,9-10,13-15H2,1-2H3/b8-5+/t16-,24+,26-,27+,28+,29+,30+,31+,32-,33+,34-,35-,36+/m0/s1 FLAZJQRJUKGAHZ-MKYGSDTQSA-N 50528370 CHEMBL4452548 Prostaglandin G/H synthase 2 Ovis aries 19600 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528370&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155522596 440736952 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296386 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@H]1O InChI=1S/C34H44O19/c1-15-24(42)28(52-33-30(45)34(46,13-36)14-48-33)25(43)32(49-15)53-29-26(44)31(47-9-8-17-3-6-19(38)21(40)11-17)50-22(12-35)27(29)51-23(41)7-4-16-2-5-18(37)20(39)10-16/h2-7,10-11,15,22,24-33,35-40,42-46H,8-9,12-14H2,1H3/b7-4+/t15-,22+,24-,25+,26+,27+,28+,29+,30-,31+,32-,33-,34+/m0/s1 KAKUSAKVVYFENV-SBLIKUSGSA-N 50528372 CHEMBL4455571 Prostaglandin G/H synthase 2 Ovis aries 21500 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528372&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5281784 440736954 C10479 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296388 COc1cc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@@H]2OC[C@](O)(COC(=O)c3ccc(O)c(O)c3)[C@H]2O)ccc1O InChI=1S/C25H30O15/c1-35-16-7-12(3-5-14(16)28)38-23-20(19(31)18(30)17(8-26)39-23)40-24-21(32)25(34,10-37-24)9-36-22(33)11-2-4-13(27)15(29)6-11/h2-7,17-21,23-24,26-32,34H,8-10H2,1H3/t17-,18-,19+,20-,21+,23-,24+,25-/m1/s1 XHGRGZDCRMCJEW-KXQNOTADSA-N 50528374 CHEMBL4556386 Prostaglandin G/H synthase 2 Ovis aries 29200 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528374&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155556784 440736956 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296391 CC(C)=CCCC(C1CNC(=N)N1)C(O)=O InChI=1S/C11H19N3O2/c1-7(2)4-3-5-8(10(15)16)9-6-13-11(12)14-9/h4,8-9H,3,5-6H2,1-2H3,(H,15,16)(H3,12,13,14) WVCALCYXKSQZFA-UHFFFAOYSA-N 50528367 CHEMBL4444825 Prostaglandin G/H synthase 2 Ovis aries 830000 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528367&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 53328941 440736949 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296392 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1 FBSKJMQYURKNSU-ZLSOWSIRSA-N 50241867 ((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-3-yl) 3-(3,4-dihydroxyphenyl)acrylate::((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)tetrahydro-2H-pyran-3-yl)3-(3,4-dihydroxyphenyl)acrylate::ACETOSIDE::CHEMBL231853::cid_24978601::cid_5281800::verbacoside::verbascoside Prostaglandin G/H synthase 2 Ovis aries 11300 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241867&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5281800 104098883 CHEMBL231853 C02757 ZINC08234351 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51296393 C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](COC(C)=O)[C@H]2OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C31H38O16/c1-14-24(38)25(39)26(40)31(44-14)47-29-27(41)30(42-10-9-17-4-7-19(34)21(36)12-17)45-22(13-43-15(2)32)28(29)46-23(37)8-5-16-3-6-18(33)20(35)11-16/h3-8,11-12,14,22,24-31,33-36,38-41H,9-10,13H2,1-2H3/b8-5+/t14-,22+,24-,25+,26+,27+,28+,29+,30+,31-/m0/s1 JBGBPOYDCGQCJC-MWKLXWFVSA-N 50528376 CHEMBL4473793 Prostaglandin G/H synthase 2 Ovis aries 9400 ChEMBL 10.1016/j.ejmech.2019.06.034 10.7270/Q2FX7DXP 31255927 Kishore, N; Kumar, P; Shanker, K; Verma, AK University of Delhi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528376&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 10462068 440736958 C02757 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51333194 COc1cc(OC)c2c(O)c3c(oc(C)cc3=O)c(-c3c(O)cc4cc(O)c5c(oc(C)cc5=O)c4c3OC)c2c1 InChI=1S/C31H24O10/c1-12-6-17(32)25-19(34)8-14-9-20(35)26(29(39-5)22(14)30(25)40-12)24-16-10-15(37-3)11-21(38-4)23(16)28(36)27-18(33)7-13(2)41-31(24)27/h6-11,34-36H,1-5H3 XZZGTSQLYYUXTL-UHFFFAOYSA-N 50539729 ASPERPYRONE A Prostaglandin G/H synthase 2 Ovis aries 6400 ChEMBL 10.1021/acs.jnatprod.9b00560 10.7270/Q23T9MRJ 32163284 Kim, MJ; Kim, DC; Kwon, J; Ryu, SM; Kwon, H; Guo, Y; Hong, SB; Kim, YC; Oh, H; Lee, D Korea University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539729&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 637172 442141292 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51343691 CS(=O)(=O)c1ccc(cc1)-c1cc(Cn2ccnc2)c2ccc(C3CCCCC3)c(C3CCCCC3)c2n1 InChI=1S/C32H37N3O2S/c1-38(36,37)27-14-12-24(13-15-27)30-20-26(21-35-19-18-33-22-35)29-17-16-28(23-8-4-2-5-9-23)31(32(29)34-30)25-10-6-3-7-11-25/h12-20,22-23,25H,2-11,21H2,1H3 OTCISVMRODWWLR-UHFFFAOYSA-N 50543860 CHEMBL4163720 Prostaglandin G/H synthase 2 Ovis aries 63 ChEMBL 10.1016/j.bmc.2020.115549 10.7270/Q22F7S0W 32503692 Gonçalves, DS; de S Melo, SM; Jacomini, AP; J V da Silva, M; Pianoski, KE; Ames, FQ; Aguiar, RP; Oliveira, AF; Volpato, H; Bidóia, DL; Nakamura, CV; Bersani-Amado, CA; Back, DF; Moura, S; Paula, FR; Rosa, FA Universidade Estadual de Maring£ (UEM) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50543860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50543860&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 145959011 442145423 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51340055 Cc1nc2ccccc2c(-c2ccccc2)c1C(=O)\C=C\c1ccc(F)cc1 InChI=1S/C25H18FNO/c1-17-24(23(28)16-13-18-11-14-20(26)15-12-18)25(19-7-3-2-4-8-19)21-9-5-6-10-22(21)27-17/h2-16H,1H3/b16-13+ ZXXQYHUKPNBJPO-DTQAZKPQSA-N 50542435 CHEMBL4642218 Prostaglandin G/H synthase 2 Ovis aries 290 ChEMBL 10.1016/j.bmcl.2020.127173 10.7270/Q2D79FZ3 32278513 Huang, ZH; Yin, LQ; Guan, LP; Li, ZH; Tan, C China-Japan Union Hospital of Jilin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50542435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50542435&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 51134246 442143998 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51340056 Cc1nc2ccccc2c(-c2ccccc2)c1C(=O)\C=C\c1ccccc1Br InChI=1S/C25H18BrNO/c1-17-24(23(28)16-15-18-9-5-7-13-21(18)26)25(19-10-3-2-4-11-19)20-12-6-8-14-22(20)27-17/h2-16H,1H3/b16-15+ HPIMFYMYLWAHOL-FOCLMDBBSA-N 50542436 CHEMBL4644802 Prostaglandin G/H synthase 2 Ovis aries 190 ChEMBL 10.1016/j.bmcl.2020.127173 10.7270/Q2D79FZ3 32278513 Huang, ZH; Yin, LQ; Guan, LP; Li, ZH; Tan, C China-Japan Union Hospital of Jilin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50542436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50542436&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 156018346 442143999 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51340057 CC(C)c1ccc(\C=C\C(=O)c2c(C)nc3ccccc3c2-c2ccccc2)cc1 InChI=1S/C28H25NO/c1-19(2)22-16-13-21(14-17-22)15-18-26(30)27-20(3)29-25-12-8-7-11-24(25)28(27)23-9-5-4-6-10-23/h4-19H,1-3H3/b18-15+ FIPMUXBLEXJJMY-OBGWFSINSA-N 50542437 CHEMBL4641093 Prostaglandin G/H synthase 2 Ovis aries 320 ChEMBL 10.1016/j.bmcl.2020.127173 10.7270/Q2D79FZ3 32278513 Huang, ZH; Yin, LQ; Guan, LP; Li, ZH; Tan, C China-Japan Union Hospital of Jilin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50542437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50542437&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 156015715 442144000 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51340058 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.bmcl.2020.127173 10.7270/Q2D79FZ3 32278513 Huang, ZH; Yin, LQ; Guan, LP; Li, ZH; Tan, C China-Japan Union Hospital of Jilin University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381113 CCn1c(S)nnc1CSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C20H20N6OS2/c1-2-25-17(23-24-19(25)28)13-29-20-22-16-9-4-3-8-15(16)18(27)26(20)12-10-14-7-5-6-11-21-14/h3-9,11H,2,10,12-13H2,1H3,(H,24,28) YQTXWWBGTDHSAT-UHFFFAOYSA-N 50558298 CHEMBL4752680 Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558298&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162653237 461828690 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381114 CCNC(=S)NNC(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C20H22N6O2S2/c1-2-21-19(29)25-24-17(27)13-30-20-23-16-9-4-3-8-15(16)18(28)26(20)12-10-14-7-5-6-11-22-14/h3-9,11H,2,10,12-13H2,1H3,(H,24,27)(H2,21,25,29) PJTFRIRBVFGSRR-UHFFFAOYSA-N 50558299 CHEMBL4755987 Prostaglandin G/H synthase 2 Ovis aries 700 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558299&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162655946 461828691 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381115 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 330 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381116 COc1ccc(cc1)C(=O)NNC(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C25H23N5O4S/c1-34-19-11-9-17(10-12-19)23(32)29-28-22(31)16-35-25-27-21-8-3-2-7-20(21)24(33)30(25)15-13-18-6-4-5-14-26-18/h2-12,14H,13,15-16H2,1H3,(H,28,31)(H,29,32) MFBCHBZOJNOKLL-UHFFFAOYSA-N 50558300 CHEMBL4757723 Prostaglandin G/H synthase 2 Ovis aries 700 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558300&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162656507 461828692 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381117 O=C(CSc1nc2ccccc2c(=O)n1CCc1ccccn1)NNC(=O)c1ccccc1 InChI=1S/C24H21N5O3S/c30-21(27-28-22(31)17-8-2-1-3-9-17)16-33-24-26-20-12-5-4-11-19(20)23(32)29(24)15-13-18-10-6-7-14-25-18/h1-12,14H,13,15-16H2,(H,27,30)(H,28,31) NHVRFKZMNQDRCY-UHFFFAOYSA-N 50558301 CHEMBL4763609 Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558301&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162661428 461828693 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381118 CCC(=O)NNC(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C20H21N5O3S/c1-2-17(26)23-24-18(27)13-29-20-22-16-9-4-3-8-15(16)19(28)25(20)12-10-14-7-5-6-11-21-14/h3-9,11H,2,10,12-13H2,1H3,(H,23,26)(H,24,27) KBOORFVZFYBCNP-UHFFFAOYSA-N 50558302 CHEMBL4776534 Prostaglandin G/H synthase 2 Ovis aries 860 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558302&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162643455 461828694 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381119 NNC(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C17H17N5O2S/c18-21-15(23)11-25-17-20-14-7-2-1-6-13(14)16(24)22(17)10-8-12-5-3-4-9-19-12/h1-7,9H,8,10-11,18H2,(H,21,23) IAQJJEKONQRALD-UHFFFAOYSA-N 50180635 CHEMBL3815106 Prostaglandin G/H synthase 2 Ovis aries 700 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180635&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 127049944 346549721 CHEMBL3815106 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381120 Clc1ccc(CSc2nc3ccccc3c(=O)n2CCc2ccccn2)cc1 InChI=1S/C22H18ClN3OS/c23-17-10-8-16(9-11-17)15-28-22-25-20-7-2-1-6-19(20)21(27)26(22)14-12-18-5-3-4-13-24-18/h1-11,13H,12,14-15H2 FOLUUDDUIGTFQD-UHFFFAOYSA-N 50558303 CHEMBL4761906 Prostaglandin G/H synthase 2 Ovis aries 10400 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558303&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155811275 461828695 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381121 CCSc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C17H17N3OS/c1-2-22-17-19-15-9-4-3-8-14(15)16(21)20(17)12-10-13-7-5-6-11-18-13/h3-9,11H,2,10,12H2,1H3 DSLUIBBKXHVEQM-UHFFFAOYSA-N 50558304 CHEMBL4795856 Prostaglandin G/H synthase 2 Ovis aries 12600 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558304&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162672933 461828696 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381122 Sc1nc2ccccc2c(=O)n1CCc1ccccn1 InChI=1S/C15H13N3OS/c19-14-12-6-1-2-7-13(12)17-15(20)18(14)10-8-11-5-3-4-9-16-11/h1-7,9H,8,10H2,(H,17,20) JRNVKGXYIMWMPQ-UHFFFAOYSA-N 50180629 CHEMBL3814962 Prostaglandin G/H synthase 2 Ovis aries 2000 ChEMBL 10.1016/j.ejmech.2016.05.066 10.7270/Q2BV7M9G 27318118 Abdel-Aziz, AA; Abou-Zeid, LA; ElTahir, KEH; Ayyad, RR; El-Sayed, MA; El-Azab, AS King Saud University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180629&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 4560677 346549715 CHEMBL3814962 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380727 COc1cc(cc(OC)c1OC)[C@@H]1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C28H28N4O5S2/c1-17-27(38-28(30-17)18-8-6-5-7-9-18)22-16-23(19-14-24(35-2)26(37-4)25(15-19)36-3)32(31-22)20-10-12-21(13-11-20)39(29,33)34/h5-15,23H,16H2,1-4H3,(H2,29,33,34)/t23-/m0/s1 CEODGYUMMDOZBN-QHCPKHFHSA-N 50558131 CHEMBL4778023 Prostaglandin G/H synthase 2 Ovis aries 1140 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558131&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162644118 461828523 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380728 COC(=O)c1cc(nn1-c1ccc(cc1)S(C)(=O)=O)-c1sc(nc1C)-c1ccccc1 InChI=1S/C22H19N3O4S2/c1-14-20(30-21(23-14)15-7-5-4-6-8-15)18-13-19(22(26)29-2)25(24-18)16-9-11-17(12-10-16)31(3,27)28/h4-13H,1-3H3 OCSYHELEJDCLND-UHFFFAOYSA-N 50558130 CHEMBL4798825 Prostaglandin G/H synthase 2 Ovis aries 1760 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558130&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162675037 461828522 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380729 COC(=O)c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)-c1sc(nc1C)-c1ccccc1 InChI=1S/C21H18N4O4S2/c1-13-19(30-20(23-13)14-6-4-3-5-7-14)17-12-18(21(26)29-2)25(24-17)15-8-10-16(11-9-15)31(22,27)28/h3-12H,1-2H3,(H2,22,27,28) OIVAQRZSLJMUMK-UHFFFAOYSA-N 50558129 CHEMBL4787167 Prostaglandin G/H synthase 2 Ovis aries 1400 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558129&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162667055 461828521 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380730 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 1540 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380731 CC(=O)Oc1ccccc1C(O)=O InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) BSYNRYMUTXBXSQ-UHFFFAOYSA-N 22360 2-(acetyloxy)benzoate::2-(acetyloxy)benzoic acid::Acetylsalicylic acid::Aspirin::Endosprin::Polopirin::Zorprin::acetylsalicylate::cid_2244 Prostaglandin G/H synthase 2 Ovis aries 2400 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search AIN 3GCL,4NSB,1TGM,1OXR,2QQT,6MQF,3IAZ 2244 49846175 15365 DB00945 4139 C01405 ZINC00000053 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381296 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 1540 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381297 C(c1ccccc1)n1cc(\C=N\n2cnnc2)c2ccccc12 InChI=1S/C18H15N5/c1-2-6-15(7-3-1)11-22-12-16(10-21-23-13-19-20-14-23)17-8-4-5-9-18(17)22/h1-10,12-14H,11H2/b21-10+ BLLNHWPEWLAAOP-UFFVCSGVSA-N 50558360 CHEMBL3212526 Prostaglandin G/H synthase 2 Ovis aries 2010 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558360&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 6858802 461828752 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381298 O=C(c1ccccc1)n1cc(\C=N\n2cnnc2)c2ccccc12 InChI=1S/C18H13N5O/c24-18(14-6-2-1-3-7-14)23-11-15(10-21-22-12-19-20-13-22)16-8-4-5-9-17(16)23/h1-13H/b21-10+ AUALVZIOMIIYHX-UFFVCSGVSA-N 50558353 CHEMBL4785230 Prostaglandin G/H synthase 2 Ovis aries 2190 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558353&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162666699 461828745 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381299 Cc1c(\N=C\c2cn(C(=O)c3ccccc3)c3ccccc23)c(=O)n(-c2ccccc2)n1C InChI=1S/C27H22N4O2/c1-19-25(27(33)31(29(19)2)22-13-7-4-8-14-22)28-17-21-18-30(24-16-10-9-15-23(21)24)26(32)20-11-5-3-6-12-20/h3-18H,1-2H3/b28-17+ XURGLESUGRETAB-OGLMXYFKSA-N 50558357 CHEMBL4777572 Prostaglandin G/H synthase 2 Ovis aries 1060 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558357&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162644404 461828749 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381300 Cc1c(\N=C\c2cn(C(=O)c3ccc(C)cc3)c3ccccc23)c(=O)n(-c2ccccc2)n1C InChI=1S/C28H24N4O2/c1-19-13-15-21(16-14-19)27(33)31-18-22(24-11-7-8-12-25(24)31)17-29-26-20(2)30(3)32(28(26)34)23-9-5-4-6-10-23/h4-18H,1-3H3/b29-17+ VYCWJDLADUPZMK-STBIYBPSSA-N 50558358 CHEMBL4795272 Prostaglandin G/H synthase 2 Ovis aries 2230 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558358&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162672410 461828750 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381301 Cc1ccc(cc1)C(=O)n1cc(\C=N\n2cnnc2)c2ccccc12 InChI=1S/C19H15N5O/c1-14-6-8-15(9-7-14)19(25)24-11-16(10-22-23-12-20-21-13-23)17-4-2-3-5-18(17)24/h2-13H,1H3/b22-10+ FBBMRTIYSYHNBF-LSHDLFTRSA-N 50558354 CHEMBL4777014 Prostaglandin G/H synthase 2 Ovis aries 980 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558354&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162642933 461828746 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381302 Cc1c(\N=C\c2cn(C(=O)c3ccc(Cl)cc3)c3ccccc23)c(=O)n(-c2ccccc2)n1C InChI=1S/C27H21ClN4O2/c1-18-25(27(34)32(30(18)2)22-8-4-3-5-9-22)29-16-20-17-31(24-11-7-6-10-23(20)24)26(33)19-12-14-21(28)15-13-19/h3-17H,1-2H3/b29-16+ VMNXVJFACODTCJ-MUFRIFMGSA-N 50558359 CHEMBL4778301 Prostaglandin G/H synthase 2 Ovis aries 1740 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558359&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162644243 461828751 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381303 Clc1ccc(cc1)C(=O)n1cc(\C=N\n2cnnc2)c2ccccc12 InChI=1S/C18H12ClN5O/c19-15-7-5-13(6-8-15)18(25)24-10-14(9-22-23-11-20-21-12-23)16-3-1-2-4-17(16)24/h1-12H/b22-9+ HXXRQLAGMACDMA-LSFURLLWSA-N 50558355 CHEMBL4762884 Prostaglandin G/H synthase 2 Ovis aries 1230 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558355&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162660367 461828747 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381304 Cc1c(\N=C\c2cn(Cc3ccccc3)c3ccccc23)c(=O)n(-c2ccccc2)n1C InChI=1S/C27H24N4O/c1-20-26(27(32)31(29(20)2)23-13-7-4-8-14-23)28-17-22-19-30(18-21-11-5-3-6-12-21)25-16-10-9-15-24(22)25/h3-17,19H,18H2,1-2H3/b28-17+ VKBRVOQNTMKLML-OGLMXYFKSA-N 50558356 CHEMBL4747604 Prostaglandin G/H synthase 2 Ovis aries 2610 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558356&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 1250444 461828748 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51381305 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 11360 ChEMBL 10.1016/j.ejmech.2016.08.013 10.7270/Q2KD22K7 27541263 Lamie, PF; Ali, WAM; Bazgier, V; Rárová, L Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380732 COc1ccc(cc1OC)[C@@H]1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C27H26N4O4S2/c1-17-26(36-27(29-17)18-7-5-4-6-8-18)22-16-23(19-9-14-24(34-2)25(15-19)35-3)31(30-22)20-10-12-21(13-11-20)37(28,32)33/h4-15,23H,16H2,1-3H3,(H2,28,32,33)/t23-/m0/s1 BIMKYGKNVQPJLZ-QHCPKHFHSA-N 50558121 CHEMBL4765087 Prostaglandin G/H synthase 2 Ovis aries 2370 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558121&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162662221 461828513 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380733 COc1cccc([C@@H]2CC(=NN2c2ccc(cc2)S(N)(=O)=O)c2sc(nc2C)-c2ccccc2)c1OC InChI=1S/C27H26N4O4S2/c1-17-26(36-27(29-17)18-8-5-4-6-9-18)22-16-23(21-10-7-11-24(34-2)25(21)35-3)31(30-22)19-12-14-20(15-13-19)37(28,32)33/h4-15,23H,16H2,1-3H3,(H2,28,32,33)/t23-/m0/s1 GGRWEHVYGXFMCS-QHCPKHFHSA-N 50558122 CHEMBL4764950 Prostaglandin G/H synthase 2 Ovis aries 3210 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558122&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162660957 461828514 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380734 COc1cc(cc(OC)c1OC)[C@@H]1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C29H29N3O5S2/c1-18-28(38-29(30-18)19-9-7-6-8-10-19)23-17-24(20-15-25(35-2)27(37-4)26(16-20)36-3)32(31-23)21-11-13-22(14-12-21)39(5,33)34/h6-16,24H,17H2,1-5H3/t24-/m0/s1 CCIBBPPUXWTGSL-DEOSSOPVSA-N 50558123 CHEMBL4789069 Prostaglandin G/H synthase 2 Ovis aries 1980 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558123&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162670273 461828515 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380735 COc1ccc(cc1OC)[C@@H]1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1sc(nc1C)-c1ccccc1 InChI=1S/C28H27N3O4S2/c1-18-27(36-28(29-18)19-8-6-5-7-9-19)23-17-24(20-10-15-25(34-2)26(16-20)35-3)31(30-23)21-11-13-22(14-12-21)37(4,32)33/h5-16,24H,17H2,1-4H3/t24-/m0/s1 JBMGVHAZCBSQAT-DEOSSOPVSA-N 50558124 CHEMBL4764063 Prostaglandin G/H synthase 2 Ovis aries 2900 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558124&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162661016 461828516 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380736 COc1cccc([C@@H]2CC(=NN2c2ccc(cc2)S(C)(=O)=O)c2sc(nc2C)-c2ccccc2)c1OC InChI=1S/C28H27N3O4S2/c1-18-27(36-28(29-18)19-9-6-5-7-10-19)23-17-24(22-11-8-12-25(34-2)26(22)35-3)31(30-23)20-13-15-21(16-14-20)37(4,32)33/h5-16,24H,17H2,1-4H3/t24-/m0/s1 ABKNIHGPAJUXHY-DEOSSOPVSA-N 50558125 CHEMBL4785437 Prostaglandin G/H synthase 2 Ovis aries 1230 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558125&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162665589 461828517 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380737 COc1cc(\C=C\C(=O)c2sc(nc2C)-c2ccccc2)cc(OC)c1OC InChI=1S/C22H21NO4S/c1-14-21(28-22(23-14)16-8-6-5-7-9-16)17(24)11-10-15-12-18(25-2)20(27-4)19(13-15)26-3/h5-13H,1-4H3/b11-10+ LBYQXORIPKEJMJ-ZHACJKMWSA-N 50558126 CHEMBL4789752 Prostaglandin G/H synthase 2 Ovis aries 1460 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558126&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162669057 461828518 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380738 COc1ccc(\C=C\C(=O)c2sc(nc2C)-c2ccccc2)cc1OC InChI=1S/C21H19NO3S/c1-14-20(26-21(22-14)16-7-5-4-6-8-16)17(23)11-9-15-10-12-18(24-2)19(13-15)25-3/h4-13H,1-3H3/b11-9+ HHYPJPCORPKTMP-PKNBQFBNSA-N 50558127 CHEMBL4750876 Prostaglandin G/H synthase 2 Ovis aries 740 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558127&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 5707206 461828519 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51380739 COc1cccc(\C=C\C(=O)c2sc(nc2C)-c2ccccc2)c1OC InChI=1S/C21H19NO3S/c1-14-20(26-21(22-14)16-8-5-4-6-9-16)17(23)13-12-15-10-7-11-18(24-2)19(15)25-3/h4-13H,1-3H3/b13-12+ MCXANCHXENDGOC-OUKQBFOZSA-N 50558128 CHEMBL4746534 Prostaglandin G/H synthase 2 Ovis aries 1890 ChEMBL 10.1016/j.bmcl.2016.04.046 10.7270/Q2WW7NC3 27158139 Abdelall, EKA; Lamie, PF; Ali, WAM Beni-Suef University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558128&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162648755 461828520 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51367101 CS(=O)(=O)c1ccc(cc1)C1C(=NOC11Cc2ccccc2C1=O)c1ccccc1 InChI=1S/C24H19NO4S/c1-30(27,28)19-13-11-16(12-14-19)21-22(17-7-3-2-4-8-17)25-29-24(21)15-18-9-5-6-10-20(18)23(24)26/h2-14,21H,15H2,1H3 LXPJJFLQNSDWPH-UHFFFAOYSA-N 50552656 CHEMBL4781457 Prostaglandin G/H synthase 2 Ovis aries 150 ChEMBL 10.1016/j.bmc.2020.115960 10.7270/Q2SX6HVR 33477020 Abolhasani, H; Zarghi, A; Komeili Movahhed, T; Abolhasani, A; Daraei, B; Dastmalchi, S Qom University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50552656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50552656&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162664224 461691424 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51367102 CS(=O)(=O)c1ccc(cc1)C1C(=NOC11Cc2ccccc2C1=O)c1ccc(F)cc1 InChI=1S/C24H18FNO4S/c1-31(28,29)19-12-8-15(9-13-19)21-22(16-6-10-18(25)11-7-16)26-30-24(21)14-17-4-2-3-5-20(17)23(24)27/h2-13,21H,14H2,1H3 ZILVDQSEUOVSBZ-UHFFFAOYSA-N 50552657 CHEMBL4794538 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.bmc.2020.115960 10.7270/Q2SX6HVR 33477020 Abolhasani, H; Zarghi, A; Komeili Movahhed, T; Abolhasani, A; Daraei, B; Dastmalchi, S Qom University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50552657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50552657&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162673305 461691425 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51367103 CS(=O)(=O)c1ccc(cc1)C1C(=NOC11Cc2ccccc2C1=O)c1ccc(Cl)cc1 InChI=1S/C24H18ClNO4S/c1-31(28,29)19-12-8-15(9-13-19)21-22(16-6-10-18(25)11-7-16)26-30-24(21)14-17-4-2-3-5-20(17)23(24)27/h2-13,21H,14H2,1H3 HMRZPWLQURMUMV-UHFFFAOYSA-N 50552658 CHEMBL4789526 Prostaglandin G/H synthase 2 Ovis aries 160 ChEMBL 10.1016/j.bmc.2020.115960 10.7270/Q2SX6HVR 33477020 Abolhasani, H; Zarghi, A; Komeili Movahhed, T; Abolhasani, A; Daraei, B; Dastmalchi, S Qom University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50552658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50552658&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162670056 461691426 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51367104 COc1ccc(cc1)C1=NOC2(Cc3ccccc3C2=O)C1c1ccc(cc1)S(C)(=O)=O InChI=1S/C25H21NO5S/c1-30-19-11-7-17(8-12-19)23-22(16-9-13-20(14-10-16)32(2,28)29)25(31-26-23)15-18-5-3-4-6-21(18)24(25)27/h3-14,22H,15H2,1-2H3 VYMRXQYAXKOZGL-UHFFFAOYSA-N 50552660 CHEMBL4762017 Prostaglandin G/H synthase 2 Ovis aries 120 ChEMBL 10.1016/j.bmc.2020.115960 10.7270/Q2SX6HVR 33477020 Abolhasani, H; Zarghi, A; Komeili Movahhed, T; Abolhasani, A; Daraei, B; Dastmalchi, S Qom University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50552660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50552660&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162659549 461691428 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51367105 COc1ccc(cc1OC)C1=NOC2(Cc3ccccc3C2=O)C1c1ccc(cc1)S(C)(=O)=O InChI=1S/C26H23NO6S/c1-31-21-13-10-17(14-22(21)32-2)24-23(16-8-11-19(12-9-16)34(3,29)30)26(33-27-24)15-18-6-4-5-7-20(18)25(26)28/h4-14,23H,15H2,1-3H3 RUFUWPLGKAUIDT-UHFFFAOYSA-N 50552661 CHEMBL4759813 Prostaglandin G/H synthase 2 Ovis aries 70 ChEMBL 10.1016/j.bmc.2020.115960 10.7270/Q2SX6HVR 33477020 Abolhasani, H; Zarghi, A; Komeili Movahhed, T; Abolhasani, A; Daraei, B; Dastmalchi, S Qom University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50552661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50552661&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162658286 461691429 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51367106 COc1cc(cc(OC)c1OC)C1=NOC2(Cc3ccccc3C2=O)C1c1ccc(cc1)S(C)(=O)=O InChI=1S/C27H25NO7S/c1-32-21-13-18(14-22(33-2)25(21)34-3)24-23(16-9-11-19(12-10-16)36(4,30)31)27(35-28-24)15-17-7-5-6-8-20(17)26(27)29/h5-14,23H,15H2,1-4H3 HUQAZAVIOXCLDE-UHFFFAOYSA-N 50552662 CHEMBL4781751 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.1016/j.bmc.2020.115960 10.7270/Q2SX6HVR 33477020 Abolhasani, H; Zarghi, A; Komeili Movahhed, T; Abolhasani, A; Daraei, B; Dastmalchi, S Qom University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50552662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50552662&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 162664415 461691430 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51367107 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 60 ChEMBL 10.1016/j.bmc.2020.115960 10.7270/Q2SX6HVR 33477020 Abolhasani, H; Zarghi, A; Komeili Movahhed, T; Abolhasani, A; Daraei, B; Dastmalchi, S Qom University of Medical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,3KK6,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51413226 COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1 InChI=1S/C25H20N6O3/c1-33-20-14-12-19(13-15-20)26-24-29-28-21(34-24)16-31-25(32)27-22(17-8-4-2-5-9-17)23(30-31)18-10-6-3-7-11-18/h2-15H,16H2,1H3,(H,26,29) STOZTMZCUWJXDR-UHFFFAOYSA-N 198171 2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3c) Prostaglandin G/H synthase 2 Ovis aries 900 ChEMBL 10.1016/j.ejmech.2021.113457 10.7270/Q2VM4H26 33892270 Ghanim, AM; Rezq, S; Ibrahim, TS; Romero, DG; Kothayer, H Zagazig University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=198171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=198171&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 122198619 318489243 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51413227 COc1ccc(\C=C2/N=C(N(NC2=O)c2ccccc2)c2cccnc2)cc1 InChI=1S/C22H18N4O2/c1-28-19-11-9-16(10-12-19)14-20-22(27)25-26(18-7-3-2-4-8-18)21(24-20)17-6-5-13-23-15-17/h2-15H,1H3,(H,25,27)/b20-14- BNAKUNINWOCARC-ZHZULCJRSA-N 50570875 CHEMBL4865603 Prostaglandin G/H synthase 2 Ovis aries 11 ChEMBL 10.1016/j.ejmech.2021.113457 10.7270/Q2VM4H26 33892270 Ghanim, AM; Rezq, S; Ibrahim, TS; Romero, DG; Kothayer, H Zagazig University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570875&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 155809809 471061020 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51413229 CCOC(=O)c1cnn(C(=O)c2cc(nc3ccc(OC)cc23)-c2ccc(Cl)cc2)c1N InChI=1S/C23H19ClN4O4/c1-3-32-23(30)18-12-26-28(21(18)25)22(29)17-11-20(13-4-6-14(24)7-5-13)27-19-9-8-15(31-2)10-16(17)19/h4-12H,3,25H2,1-2H3 NNOGPQHEKLDSBU-UHFFFAOYSA-N 50570876 CHEMBL4867924 Prostaglandin G/H synthase 2 Ovis aries 260 ChEMBL 10.1016/j.ejmech.2021.113457 10.7270/Q2VM4H26 33892270 Ghanim, AM; Rezq, S; Ibrahim, TS; Romero, DG; Kothayer, H Zagazig University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570876&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 164620988 471061021 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51413234 COc1ccc(cc1)-c1nn(cc1\C=C\c1cc(C(=O)N2CCOCC2)c2cc(Cl)ccc2n1)-c1ccc(Cl)cc1 InChI=1S/C32H26Cl2N4O3/c1-40-27-11-3-21(4-12-27)31-22(20-38(36-31)26-9-5-23(33)6-10-26)2-8-25-19-29(32(39)37-14-16-41-17-15-37)28-18-24(34)7-13-30(28)35-25/h2-13,18-20H,14-17H2,1H3/b8-2+ UTIFXRVYZVJPBY-KRXBUXKQSA-N 50570879 CHEMBL4859626 Prostaglandin G/H synthase 2 Ovis aries 100 ChEMBL 10.1016/j.ejmech.2021.113457 10.7270/Q2VM4H26 33892270 Ghanim, AM; Rezq, S; Ibrahim, TS; Romero, DG; Kothayer, H Zagazig University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570879&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 164617094 471061024 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51527318 CCOC(=O)[C@H](CO)NC(=O)c1cccc(O)c1O InChI=1S/C12H15NO6/c1-2-19-12(18)8(6-14)13-11(17)7-4-3-5-9(15)10(7)16/h3-5,8,14-16H,2,6H2,1H3,(H,13,17)/t8-/m0/s1 ZNAULGVROLOSBS-QMMMGPOBSA-N 50528369 CHEMBL4472111 Prostaglandin G/H synthase 2 Ovis aries 2800 ChEMBL 10.7270/Q28W3JJ0 36880830 Ju, Z; Shang, Z; Mahmud, T; Fang, J; Liu, Y; Pan, Q; Lin, X; Chen, F Zhejiang University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528369&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 139588023 440736951 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51510958 Cc1[nH]n(-c2ccccc2)c(=O)c1CNC(=S)Nc1ccccc1 InChI=1S/C18H18N4OS/c1-13-16(12-19-18(24)20-14-8-4-2-5-9-14)17(23)22(21-13)15-10-6-3-7-11-15/h2-11,21H,12H2,1H3,(H2,19,20,24) CLWNURLBTVRFAA-UHFFFAOYSA-N 123791 1-[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4- yl)methyl]-3-phenylthiourea (5d) Prostaglandin G/H synthase 2 Ovis aries 200 ChEMBL 10.7270/Q2DR30QG 31761383 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123791&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766201 225150200 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51510959 Cc1[nH]n(-c2ccccc2)c(=O)c1CNc1ccc(cc1)S(N)(=O)=O InChI=1S/C17H18N4O3S/c1-12-16(17(22)21(20-12)14-5-3-2-4-6-14)11-19-13-7-9-15(10-8-13)25(18,23)24/h2-10,19-20H,11H2,1H3,(H2,18,23,24) DNGVGHPGBVVYBV-UHFFFAOYSA-N 123793 4-{[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol- 4-yl)methyl]amino} benzene sulfonamide (5f) Prostaglandin G/H synthase 2 Ovis aries 1000 ChEMBL 10.7270/Q2DR30QG 31761383 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=123793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=123793&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 86766203 225150202 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51510960 O=C1CC(Nc2ccccc2NC(=S)NC2CCCCC2)=NN1 InChI=1S/C16H21N5OS/c22-15-10-14(20-21-15)18-12-8-4-5-9-13(12)19-16(23)17-11-6-2-1-3-7-11/h4-5,8-9,11H,1-3,6-7,10H2,(H,18,20)(H,21,22)(H2,17,19,23) VUDPSVOXBVXJAE-UHFFFAOYSA-N 50608300 CHEMBL5282305 Prostaglandin G/H synthase 2 Ovis aries 2.8 ChEMBL 10.7270/Q2DR30QG 31761383 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608300&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171355012 494498048 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51510961 CCCCNc1nc2ccccc2n1C1=NN=C(O)C1 InChI=1S/C14H17N5O/c1-2-3-8-15-14-16-10-6-4-5-7-11(10)19(14)12-9-13(20)18-17-12/h4-7H,2-3,8-9H2,1H3,(H,15,16)(H,18,20) RCXZCYBEONCORL-UHFFFAOYSA-N 50608301 CHEMBL5269492 Prostaglandin G/H synthase 2 Ovis aries 4.7 ChEMBL 10.7270/Q2DR30QG 31761383 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608301&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171342812 494498049 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51510962 NS(=O)(=O)c1ccc(cc1)N1N=C\C(=N\Nc2ccccc2C(O)=O)C1=O InChI=1S/C16H13N5O5S/c17-27(25,26)11-7-5-10(6-8-11)21-15(22)14(9-18-21)20-19-13-4-2-1-3-12(13)16(23)24/h1-9,19H,(H,23,24)(H2,17,25,26)/b20-14- VHNWYITXUYHPTH-ZHZULCJRSA-N 50608302 CHEMBL5278316 Prostaglandin G/H synthase 2 Ovis aries 770 ChEMBL 10.7270/Q2DR30QG 31761383 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608302&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 170847393 494498050 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51510963 NS(=O)(=O)c1ccc(cc1)N1N=C\C(=N\Nc2ccc(cc2)C(O)=O)C1=O InChI=1S/C16H13N5O5S/c17-27(25,26)13-7-5-12(6-8-13)21-15(22)14(9-18-21)20-19-11-3-1-10(2-4-11)16(23)24/h1-9,19H,(H,23,24)(H2,17,25,26)/b20-14- VHLMYGKIBYSFSH-ZHZULCJRSA-N 50608303 CHEMBL5274726 Prostaglandin G/H synthase 2 Ovis aries 720 ChEMBL 10.7270/Q2DR30QG 31761383 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608303&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171352847 494498051 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51510964 NS(=O)(=O)c1ccc(N\N=C2\C=NN(C2=O)c2ccccc2C(O)=O)cc1 InChI=1S/C16H13N5O5S/c17-27(25,26)11-7-5-10(6-8-11)19-20-13-9-18-21(15(13)22)14-4-2-1-3-12(14)16(23)24/h1-9,19H,(H,23,24)(H2,17,25,26)/b20-13- SXKXNSIRUQIHKZ-MOSHPQCFSA-N 50608304 CHEMBL5286507 Prostaglandin G/H synthase 2 Ovis aries 660 ChEMBL 10.7270/Q2DR30QG 31761383 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50608304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50608304&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171346754 494498052 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518759 COc1ccnc(Nc2n[nH]c(N)c2C#N)c1 InChI=1S/C10H10N6O/c1-17-6-2-3-13-8(4-6)14-10-7(5-11)9(12)15-16-10/h2-4H,1H3,(H4,12,13,14,15,16) LGYGNOQKNCICNN-UHFFFAOYSA-N 50611377 CHEMBL5278118 Prostaglandin G/H synthase 2 Ovis aries 4700 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611377&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171356592 494501125 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518760 COc1ccnc(Nc2nn3c(SC)c(C#N)c(N)nc3c2C#N)c1 InChI=1S/C15H12N8OS/c1-24-8-3-4-19-11(5-8)20-13-10(7-17)14-21-12(18)9(6-16)15(25-2)23(14)22-13/h3-5H,1-2H3,(H2,18,21)(H,19,20,22) RMSJQJOHBDAMEL-UHFFFAOYSA-N 50611378 CHEMBL5274868 Prostaglandin G/H synthase 2 Ovis aries 4400 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611378&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171357232 494501126 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518761 COc1ccnc(Nc2nn3c(SC)c(C#N)c(O)nc3c2C#N)c1 InChI=1S/C15H11N7O2S/c1-24-8-3-4-18-11(5-8)19-12-9(6-16)13-20-14(23)10(7-17)15(25-2)22(13)21-12/h3-5H,1-2H3,(H,20,23)(H,18,19,21) ZZHPMCXUYDLUON-UHFFFAOYSA-N 50611379 CHEMBL5275045 Prostaglandin G/H synthase 2 Ovis aries 1400 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611379&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171352207 494501127 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518762 COc1ccnc(Nc2nn3c(C)cc(C)nc3c2C#N)c1 InChI=1S/C15H14N6O/c1-9-6-10(2)21-15(18-9)12(8-16)14(20-21)19-13-7-11(22-3)4-5-17-13/h4-7H,1-3H3,(H,17,19,20) MWJHAGJIVBGATF-UHFFFAOYSA-N 50611380 CHEMBL5280862 Prostaglandin G/H synthase 2 Ovis aries 1110 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611380&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171353785 494501128 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518763 CCOc1cc(C)nc2c(C#N)c(Nc3cc(OC)ccn3)nn12 InChI=1S/C16H16N6O2/c1-4-24-14-7-10(2)19-16-12(9-17)15(21-22(14)16)20-13-8-11(23-3)5-6-18-13/h5-8H,4H2,1-3H3,(H,18,20,21) KYOSHYZHJHZGQB-UHFFFAOYSA-N 50611381 CHEMBL5266517 Prostaglandin G/H synthase 2 Ovis aries 2700 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611381&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171351310 494501129 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518764 CCOc1cc(N)n2nc(Nc3cc(OC)ccn3)c(C#N)c2n1 InChI=1S/C15H15N7O2/c1-3-24-13-7-11(17)22-15(20-13)10(8-16)14(21-22)19-12-6-9(23-2)4-5-18-12/h4-7H,3,17H2,1-2H3,(H,18,19,21) PSVVFOKDFJMUAF-UHFFFAOYSA-N 50611382 CHEMBL5267419 Prostaglandin G/H synthase 2 Ovis aries 2200 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611382&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171351488 494501130 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518765 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US11786535, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 1110 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518766 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US11786535, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 3650 ChEMBL 10.7270/Q2WW7NX8 36325400 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518478 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC(=S)Nc3ccccc3)c2c1 InChI=1S/C26H22ClN3O3S/c1-16-21(15-24(31)29-26(34)28-19-6-4-3-5-7-19)22-14-20(33-2)12-13-23(22)30(16)25(32)17-8-10-18(27)11-9-17/h3-14H,15H2,1-2H3,(H2,28,29,31,34) JKDBKHTYLIFOGH-UHFFFAOYSA-N 50611277 CHEMBL5276908 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611277&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171354402 494501025 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518479 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC(=S)Nc3ccc(F)cc3)c2c1 InChI=1S/C26H21ClFN3O3S/c1-15-21(14-24(32)30-26(35)29-19-9-7-18(28)8-10-19)22-13-20(34-2)11-12-23(22)31(15)25(33)16-3-5-17(27)6-4-16/h3-13H,14H2,1-2H3,(H2,29,30,32,35) JJTWXUGJJCQZTD-UHFFFAOYSA-N 50611278 CHEMBL5290545 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611278&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171358630 494501026 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518480 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC(=S)Nc3ccc(Cl)cc3)c2c1 InChI=1S/C26H21Cl2N3O3S/c1-15-21(14-24(32)30-26(35)29-19-9-7-18(28)8-10-19)22-13-20(34-2)11-12-23(22)31(15)25(33)16-3-5-17(27)6-4-16/h3-13H,14H2,1-2H3,(H2,29,30,32,35) CKVDXPYUDXZVST-UHFFFAOYSA-N 50611279 CHEMBL5266123 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611279&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171350154 494501027 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518481 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC(=S)Nc3ccc(C)cc3)c2c1 InChI=1S/C27H24ClN3O3S/c1-16-4-10-20(11-5-16)29-27(35)30-25(32)15-22-17(2)31(24-13-12-21(34-3)14-23(22)24)26(33)18-6-8-19(28)9-7-18/h4-14H,15H2,1-3H3,(H2,29,30,32,35) OQOQKNZFRFFKNQ-UHFFFAOYSA-N 50611280 CHEMBL5268937 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611280&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171343835 494501028 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518482 COc1ccc(NC(=S)NC(=O)Cc2c(C)n(C(=O)c3ccc(Cl)cc3)c3ccc(OC)cc23)cc1 InChI=1S/C27H24ClN3O4S/c1-16-22(15-25(32)30-27(36)29-19-8-10-20(34-2)11-9-19)23-14-21(35-3)12-13-24(23)31(16)26(33)17-4-6-18(28)7-5-17/h4-14H,15H2,1-3H3,(H2,29,30,32,36) WTALRFJFXVIOTJ-UHFFFAOYSA-N 50611281 CHEMBL5270337 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611281&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171344237 494501029 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518483 COC(=O)c1ccc(NC(=S)NC(=O)Cc2c(C)n(C(=O)c3ccc(Cl)cc3)c3ccc(OC)cc23)cc1 InChI=1S/C28H24ClN3O5S/c1-16-22(15-25(33)31-28(38)30-20-10-6-18(7-11-20)27(35)37-3)23-14-21(36-2)12-13-24(23)32(16)26(34)17-4-8-19(29)9-5-17/h4-14H,15H2,1-3H3,(H2,30,31,33,38) WJJBVVABDFZQLH-UHFFFAOYSA-N 50611282 CHEMBL5280219 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611282&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171356379 494501030 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518484 CCOC(=O)c1ccc(NC(=S)NC(=O)Cc2c(C)n(C(=O)c3ccc(Cl)cc3)c3ccc(OC)cc23)cc1 InChI=1S/C29H26ClN3O5S/c1-4-38-28(36)19-7-11-21(12-8-19)31-29(39)32-26(34)16-23-17(2)33(25-14-13-22(37-3)15-24(23)25)27(35)18-5-9-20(30)10-6-18/h5-15H,4,16H2,1-3H3,(H2,31,32,34,39) CNWMVFFPTJIZQZ-UHFFFAOYSA-N 50611283 CHEMBL5282951 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611283&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171354678 494501031 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518485 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NNC(=O)CC#N)c2c1 InChI=1S/C22H19ClN4O4/c1-13-17(12-21(29)26-25-20(28)9-10-24)18-11-16(31-2)7-8-19(18)27(13)22(30)14-3-5-15(23)6-4-14/h3-8,11H,9,12H2,1-2H3,(H,25,28)(H,26,29) LAZXOKRZXFPFEC-UHFFFAOYSA-N 50611284 CHEMBL5282735 Prostaglandin G/H synthase 2 Ovis aries 400 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611284&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171355029 494501032 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518486 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)Nn3c(C)cc(C)c(C#N)c3=O)c2c1 InChI=1S/C27H23ClN4O4/c1-15-11-16(2)32(27(35)23(15)14-29)30-25(33)13-21-17(3)31(24-10-9-20(36-4)12-22(21)24)26(34)18-5-7-19(28)8-6-18/h5-12H,13H2,1-4H3,(H,30,33) MFAOGOLWUXCFFL-UHFFFAOYSA-N 50611285 CHEMBL5277594 Prostaglandin G/H synthase 2 Ovis aries 310 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611285&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171355552 494501033 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518487 COc1ccc2n(C(=O)c3ccc(cc3)N3CCCCC3)c(C)c(CC(=O)Nn3c(N)c(C#N)c(-c4ccccc4)c(C#N)c3=O)c2c1 InChI=1S/C37H33N7O4/c1-23-28(20-33(45)41-44-35(40)30(21-38)34(31(22-39)37(44)47)24-9-5-3-6-10-24)29-19-27(48-2)15-16-32(29)43(23)36(46)25-11-13-26(14-12-25)42-17-7-4-8-18-42/h3,5-6,9-16,19H,4,7-8,17-18,20,40H2,1-2H3,(H,41,45) WWGRQDNBWICVDH-UHFFFAOYSA-N 50611286 CHEMBL5278619 Prostaglandin G/H synthase 2 Ovis aries 150 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611286&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171355255 494501034 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518488 COc1ccc2n(C(=O)c3ccc(cc3)N3CCCCC3)c(C)c(CC(=O)Nn3c(N)c(C#N)c(-c4ccc(Cl)cc4)c(C#N)c3=O)c2c1 InChI=1S/C37H32ClN7O4/c1-22-28(19-33(46)42-45-35(41)30(20-39)34(31(21-40)37(45)48)23-6-10-25(38)11-7-23)29-18-27(49-2)14-15-32(29)44(22)36(47)24-8-12-26(13-9-24)43-16-4-3-5-17-43/h6-15,18H,3-5,16-17,19,41H2,1-2H3,(H,42,46) XQWLZRKDKNNUOC-UHFFFAOYSA-N 50611287 CHEMBL5278592 Prostaglandin G/H synthase 2 Ovis aries 90 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611287&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171354070 494501035 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518489 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US11786535, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 890 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518490 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) CGIGDMFJXJATDK-UHFFFAOYSA-N 17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US11786535, Compound Indomethacin::US9271961, Indomethacin::indometacin Prostaglandin G/H synthase 2 Ovis aries 87 ChEMBL 10.7270/Q2JM2FV4 35685617 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17638&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search IMN 3ADS,3ADX,4YIA,1Z9H,4XUM,7FCG,2ZB8,2BXK,2BXM,2BXQ,3H1X,4COX,1S2A,4JQ4,2DM6,3UGR,3UG8,3IB1,4KYK,4IKI,4IK7,2OTH,3FO7,4EIX 3715 46517802 49662 CHEMBL6 DB00328 1909 C01926 ZINC00601283 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518592 O[C@H]1O[C@@](O)(CNC2=C(C#N)C(c3ccc(Cl)cc3)c3c(O2)[nH]c(=S)[nH]c3=O)[C@H](O)[C@H](O)[C@@H]1O InChI=1S/C20H19ClN4O8S/c21-8-3-1-7(2-4-8)10-9(5-22)16(32-17-11(10)15(29)24-19(34)25-17)23-6-20(31)14(28)12(26)13(27)18(30)33-20/h1-4,10,12-14,18,23,26-28,30-31H,6H2,(H2,24,25,29,34)/t10?,12-,13+,14-,18+,20+/m1/s1 DNWQRABCPKVEES-IGMJBKBHSA-N 50611335 CHEMBL5279318 Prostaglandin G/H synthase 2 Ovis aries 40 ChEMBL 10.7270/Q2DV1Q3C 35694689 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611335&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171353728 494501083 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518593 Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) RZEKVGVHFLEQIL-UHFFFAOYSA-N 11639 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide::CHEMBL118::CLX::Celebrex::Celecoxib::US10322118, Urea-Based Scaffold Entry 9::US11478464, Compound Celecoxib::US11786535, Compound Celecoxib::US8741944, Comparative Compound::US9388139, Celecoxib::cid_2662 Prostaglandin G/H synthase 2 Ovis aries 40 ChEMBL 10.7270/Q2DV1Q3C 35694689 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11639&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search CEL 3LN1,5JW1,7ZEJ,4FIM,1OQ5 2662 46512162 41423 CHEMBL118 DB00482 2892 C07589 ZINC02570895 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208 51518594 Clc1ccc(cc1)C1c2c(Oc3ncn(-c4ccccc4)c(=N)c13)[nH]c(=S)[nH]c2=O InChI=1S/C21H14ClN5O2S/c22-12-8-6-11(7-9-12)14-15-17(23)27(13-4-2-1-3-5-13)10-24-19(15)29-20-16(14)18(28)25-21(30)26-20/h1-10,14,23H,(H2,25,26,28,30) WPBQNKZVDYIKSC-UHFFFAOYSA-N 50611336 CHEMBL5274256 Prostaglandin G/H synthase 2 Ovis aries 40 ChEMBL 10.7270/Q2DV1Q3C 35694689 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=6274&target=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611336&enzyme=Prostaglandin+G%2FH+synthase+2&column=ki&startPg=0&Increment=50&submit=Search 171355426 494501084 1 MLARALLLCAAVVCGAANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCTTPEFLTRIKLLLKPTPDTVHYILTHFKGVWNIVNKISFLRNMIMRYVLTSRSHLIESPPTYNVHYSYKSWEAFSNLSYYTRALPPVPDDCPTPMGVKGRKELPDSKEVVKKVLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTDIERGPAFTKGKNHGVDLSHVYGESLERQHNRRLFKDGKMKYQMINGEMYPPTVKDTQVEMIYPPHIPEHLKFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNQQFQYQNRIAAEFNTLYHWHPLLPDVFQIDGQEYNYQQFIYNNSVLLEHGVTQFVESFTRQIAGRVAGRRNLPAAVEKVSKASLDQSREMKYQSFNEYRKRFLLKPYESFEELTGEKEMAAELEALYGDIDAMELYPALLVEKPAPDAIFGETMVEAGAPFSLKGLMGNPICSPEYWKPSTFGGEVGFKIINTASIQSLICSNVKGCPFTSFSVQDAHLTKTVTINASSSHSGLDDINPTVLLKERSTEL 1DDX,3NTG,4M11 Prostaglandin G/H synthase 2 PGH2_SHEEP P79208